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Antti Pertovaara

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Hong Wei; Hanna Viisanen; Diana Amorim; Ari Koivisto; Antti Pertovaara
Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy.
Hong Wei; Antti Pertovaara
Regulation of neuropathic hypersensitivity by α(2) -adrenoceptors in the pontine A7 cell group.
Hugo Leite-Almeida; Antti Pertovaara; Nuno Ribeiro-Costa; Nuno Sousa; Hong Wei; Helena Anjos-Martins; João J Cerqueira; Armando Almeida
Differential effects of left/right neuropathy on rats' anxiety and cognitive behavior.

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All Publications

2013: Hong Wei; Hanna Viisanen; Diana Amorim; Ari Koivisto; Antti Pertovaara
Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy.
Pharmacology, biochemistry, and behavior 2013;104():90-6.
2013: Hong Wei; Antti Pertovaara
Regulation of neuropathic hypersensitivity by α(2) -adrenoceptors in the pontine A7 cell group.
Basic & clinical pharmacology & toxicology 2013;112(2):90-5.
2012: Hugo Leite-Almeida; Antti Pertovaara; Nuno Ribeiro-Costa; Nuno Sousa; Hong Wei; Helena Anjos-Martins; João J Cerqueira; Armando Almeida
Differential effects of left/right neuropathy on rats' anxiety and cognitive behavior.
Pain 2012;153(11):2218-25.
2012: Hanna Viisanen; Osei B Ansah; Antti Pertovaara
The role of the dopamine D2 receptor in descending control of pain induced by motor cortex stimulation in the neuropathic rat.
Brain research bulletin 2012;89(3-4):133-43.
2012: Nora Hagelberg; Jarmo Hietala; Sargo Aalto; Kjell Någren; Antti Pertovaara; Ullamari Pesonen; Harry Scheinin; Lauri Tuominen; Ilkka K Martikainen
Striatal μ-opioid receptor availability predicts cold pressor pain threshold in healthy human subjects.
Neuroscience letters 2012;521(1):11-4.
2012: Hong Wei; Mari Karimaa; Ari Koivisto; Timo Korjamo; Antti Pertovaara
Transient receptor potential ankyrin 1 ion channel contributes to guarding pain and mechanical hypersensitivity in a rat model of postoperative pain.
Anesthesiology 2012;117(1):137-48.
2012: Ari Koivisto; Katja Kuokkanen; Ken Lindstedt; Karl E Akerman; Hugh Chapman; Mika Hukkanen; Marja Saarnilehto; Hanna Viisanen; Hong Wei; Antti Pertovaara
Inhibiting TRPA1 ion channel reduces loss of cutaneous nerve fiber function in diabetic animals: sustained activation of the TRPA1 channel contributes to the pathogenesis of peripheral diabetic neuropathy.
Pharmacological research : the official journal of the Italian Pharmacological Society 2012;65(1):149-58.
2011: Antti Pertovaara; Ari Koivisto
TRPA1 ion channel in the spinal dorsal horn as a therapeutic target in central pain hypersensitivity and cutaneous neurogenic inflammation.
European journal of pharmacology 2011;666(1-3):1-4.
2011: Filipa Pinto-Ribeiro; Armando Almeida; Osei B Ansah; Antti Pertovaara
Response properties of nociceptive neurons in the caudal ventrolateral medulla (CVLM) in monoarthritic and healthy control rats: modulation of responses by the paraventricular nucleus of the hypothalamus (PVN).
Brain research bulletin 2011;86(1-2):82-90.
2011: Petri Savolainen; Synnöve Carlson; Robert Boldt; Tuomas Neuvonen; Henri Hannula; Jaana Hiltunen; Oili Salonen; Yuan-Ye Ma; Antti Pertovaara
Facilitation of tactile working memory by top-down suppression from prefrontal to primary somatosensory cortex during sensory interference.
Behavioural brain research 2011;219(2):387-90.
2011: Hong Wei; Ari Koivisto; Marja Saarnilehto; Hugh Chapman; Katja Kuokkanen; Bin Hao; Jin-Lu Huang; Yong-Xiang Wang; Antti Pertovaara
Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat.
Pain 2011;152(3):582-91.
2010: Hong Wei; Bin Hao; Jin-Lu Huang; Ai-Niu Ma; Xin-Yan Li; Yong-Xiang Wang; Antti Pertovaara
Intrathecal administration of a gap junction decoupler, an inhibitor of Na(+)-K(+)-2Cl(-) cotransporter 1, or a GABA(A) receptor agonist attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat.
Pharmacology, biochemistry, and behavior 2010;97(2):377-83.
2010: O Kambur; R Talka; O B Ansah; V K Kontinen; Antti Pertovaara; Eija Kalso; P T Männistö
Inhibitors of catechol-O-methyltransferase sensitize mice to pain.
British journal of pharmacology 2010;161(7):1553-65.
2010: Nora Bourbia; Osei B Ansah; Antti Pertovaara
Corticotropin-releasing factor in the rat amygdala differentially influences sensory-discriminative and emotional-like pain response in peripheral neuropathy.
The journal of pain : official journal of the American Pain Society 2010;11(12):1461-71.
2010: Hong Wei; Ari Koivisto; Antti Pertovaara
Spinal TRPA1 ion channels contribute to cutaneous neurogenic inflammation in the rat.
Neuroscience letters 2010;479(3):253-6.
2010: Hanna Viisanen; Antti Pertovaara
Roles of the rostroventromedial medulla and the spinal 5-HT(1A) receptor in descending antinociception induced by motor cortex stimulation in the neuropathic rat.
Neuroscience letters 2010;476(3):133-7.
2010: D Tikhonravov; Tuomas Neuvonen; Antti Pertovaara; K Savioja; Timo Ruusuvirta; Risto Näätänen; Synnöve Carlson
Dose-related effects of memantine on a mismatch negativity-like response in anesthetized rats.
Neuroscience 2010;167(4):1175-82.
2010: Osei B Ansah; Nora BOURBIA; Leonor Gonçalves; Armando Almeida; Antti Pertovaara
Influence of amygdaloid glutamatergic receptors on sensory and emotional pain-related behavior in the neuropathic rat.
Behavioural brain research 2010;209(1):174-8.
2010: Hong Wei; Hugh Chapman; Marja Saarnilehto; Katja Kuokkanen; Ari Koivisto; Antti Pertovaara
Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat.
Neuropharmacology 2010;58(3):578-84.
2010: Hanna Viisanen; Antti Pertovaara
Antinociception by motor cortex stimulation in the neuropathic rat: does the locus coeruleus play a role?
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2010;201(2):283-96.
2010: Henri Hannula; Tuomas Neuvonen; Petri Savolainen; Jukka Hiltunen; Yuan-Ye Ma; Hanne Antila; Oili Salonen; Synnöve Carlson; Antti Pertovaara
Increasing top-down suppression from prefrontal cortex facilitates tactile working memory.
NeuroImage 2010;49(1):1091-8.
2009: Ilkka K Martikainen; Jussi Hirvonen; Ullamari Pesonen; Nora Hagelberg; Heikki Laurikainen; Heikki Tuikkala; Jaana Kajander; Kjell Någren; Jarmo Hietala; Antti Pertovaara
Differential associations between brain 5-HT(1A) receptor binding and response to pain versus touch.
Journal of neural transmission (Vienna, Austria : 1996) 2009;116(7):821-30.
2009: Hong Wei; Minna M Hämäläinen; Marja Saarnilehto; Ari Koivisto; Antti Pertovaara
Attenuation of mechanical hypersensitivity by an antagonist of the TRPA1 ion channel in diabetic animals.
Anesthesiology 2009;111(1):147-54.
2009: Hugo Leite-Almeida; Luis Almeida-Torres; Ana Raquel Mesquita; Antti Pertovaara; Nuno Sousa; João J Cerqueira; Armando Almeida
The impact of age on emotional and cognitive behaviours triggered by experimental neuropathy in rats.
Pain 2009;144(1-2):57-65.
2009: Tuija H Nieminen; Nora M Hagelberg; Teijo I Saari; Antti Pertovaara; Mikko Neuvonen; Kari Laine; Pertti J Neuvonen; Klaus T Olkkola
Rifampin greatly reduces the plasma concentrations of intravenous and oral oxycodone.
Anesthesiology 2009;110(6):1371-8.
2009: Hong Wei; Hanna Viisanen; Antti Pertovaara
Descending modulation of neuropathic hypersensitivity by dopamine D2 receptors in or adjacent to the hypothalamic A11 cell group.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;59(5):355-63.
2009: Tanja Valmunen; Antti Pertovaara; Tero Taiminen; Arja Virtanen; Riitta Parkkola; Satu Jääskeläinen
Modulation of facial sensitivity by navigated rTMS in healthy subjects.
Pain 2009;142(1-2):149-58.
2009: Osei B Ansah; Leonor Gonçalves; Armando Almeida; Antti Pertovaara
Enhanced pronociception by amygdaloid group I metabotropic glutamate receptors in nerve-injured animals.
Experimental neurology 2009;216(1):66-74.
2008: Leonor Gonçalves; Rui Silva; Filipa Pinto-Ribeiro; José M Pêgo; João M Bessa; Antti Pertovaara; Nuno Sousa; Armando Almeida
Neuropathic pain is associated with depressive behaviour and induces neuroplasticity in the amygdala of the rat.
Experimental neurology 2008;213(1):48-56.
2008: Antti Pertovaara; Hong Wei
Dual influence of the striatum on neuropathic hypersensitivity.
Pain 2008;137(1):50-9.
2008: Hong Wei; Ainiu Ma; Yong-Xiang Wang; Antti Pertovaara
Role of spinal 5-HT receptors in cutaneous hypersensitivity induced by REM sleep deprivation.
Pharmacological research : the official journal of the Italian Pharmacological Society 2008;57(6):469-75.
2008: Henri Hannula; Tuomas Neuvonen; Petri Savolainen; Taru Tukiainen; Oili Salonen; Synnöve Carlson; Antti Pertovaara
Navigated transcranial magnetic stimulation of the primary somatosensory cortex impairs perceptual processing of tactile temporal discrimination.
Neuroscience letters 2008;437(2):144-7.
2008: Dmitry Tikhonravov; Tuomas Neuvonen; Antti Pertovaara; Kati Savioja; Timo Ruusuvirta; Risto Näätänen; Synnöve Carlson
Effects of an NMDA-receptor antagonist MK-801 on an MMN-like response recorded in anesthetized rats.
Brain research 2008;1203():97-102.
2008: Filipa Pinto-Ribeiro; Osei B Ansah; Armando Almeida; Antti Pertovaara
Influence of arthritis on descending modulation of nociception from the paraventricular nucleus of the hypothalamus.
Brain research 2008;1197():63-75.
2007: Ilkka K Martikainen; Jussi Hirvonen; Jaana Kajander; Nora Hagelberg; Heikki Mansikka; Kjell Någren; Jarmo Hietala; Antti Pertovaara
Correlation of human cold pressor pain responses with 5-HT(1A) receptor binding in the brain.
Brain research 2007;1172():21-31.
2007: Leonor Gonçalves; Armando Almeida; Antti Pertovaara
Pronociceptive changes in response properties of rostroventromedial medullary neurons in a rat model of peripheral neuropathy.
The European journal of neuroscience 2007;26(8):2188-95.
2007: Osei B Ansah; Antti Pertovaara
Peripheral suppression of arthritic pain by intraarticular fadolmidine, an alpha 2-adrenoceptor agonist, in the rat.
Anesthesia and analgesia 2007;105(1):245-50.
2007: Hanna Viisanen; Antti Pertovaara
Influence of peripheral nerve injury on response properties of locus coeruleus neurons and coeruleospinal antinociception in the rat.
Neuroscience 2007;146(4):1785-94.
2007: Osei B Ansah; Hugo Leite-Almeida; Hong Wei; Antti Pertovaara
Striatal dopamine D2 receptors attenuate neuropathic hypersensitivity in the rat.
Experimental neurology 2007;205(2):536-46.
2006: Hong Wei; Antti Pertovaara
Spinal and pontine alpha2-adrenoceptors have opposite effects on pain-related behavior in the neuropathic rat.
European journal of pharmacology 2006;551(1-3):41-9.
2006: Antti Pertovaara
Noradrenergic pain modulation.
Progress in neurobiology 2006;80(2):53-83.
2006: Hong Wei; Antti Pertovaara
5-HT(1A) receptors in endogenous regulation of neuropathic hypersensitivity in the rat.
European journal of pharmacology 2006;535(1-3):157-65.
2006: Shelley Ylioja; Synnöve Carlson; Tuukka T Raij; Antti Pertovaara
Localization of touch versus heat pain in the human hand: a dissociative effect of temporal parameters on discriminative capacity and decision strategy.
Pain 2006;121(1-2):6-13.
2006: Antti Pertovaara; Armando Almeida
Chapter 13 Descending inhibitory systems.
Handbook of clinical neurology 2006;81():179-92.
2005: Henri Hannula; Shelley Ylioja; Antti Pertovaara; Antti Korvenoja; Jarmo Ruohonen; Risto Juhani Ilmoniemi; Synnöve Carlson
Somatotopic blocking of sensation with navigated transcranial magnetic stimulation of the primary somatosensory cortex.
Human brain mapping 2005;26(2):100-9.
2005: Heikki Mansikka; Eric Erbs; Emiliana Borrelli; Antti Pertovaara
Influence of the dopamine D2 receptor knockout on pain-related behavior in the mouse.
Brain research 2005;1052(1):82-7.
2005: Ilkka K Martikainen; Nora Hagelberg; Heikki Mansikka; Jarmo Hietala; Kjell Någren; Harry Scheinin; Antti Pertovaara
Association of striatal dopamine D2/D3 receptor binding potential with pain but not tactile sensitivity or placebo analgesia.
Neuroscience letters 2005;376(3):149-53.
2005: Antti Pertovaara; Antti Haapalinna; Jouni Sirviö; Raine Virtanen
Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist.
CNS drug reviews 2005;11(3):273-88.
2005: Antti Pertovaara; Maria Ostergård; Minna-Liisa Ankö; S Lehti-Koivunen; A Brandt; W Hong; Esa R Korpi; Pertti Panula
RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat.
Neuroscience 2005;134(3):1023-32.
2004: Nora Hagelberg; Satu Jääskeläinen; Ilkka K Martikainen; Heikki Mansikka; Heli Forssell; Harry Scheinin; Jarmo Hietala; Antti Pertovaara
Striatal dopamine D2 receptors in modulation of pain in humans: a review.
European journal of pharmacology 2004;500(1-3):187-92.
2004: Antti Pertovaara; Ilkka Linnankoski; Denis Artchakov; Pia Rämä; Synnöve Carlson
A potential aphrodisiac for female macaques.
Pharmacology, biochemistry, and behavior 2004;79(1):137-41.
2004: Antti Pertovaara; Ilkka K Martikainen; Nora Hagelberg; Heikki Mansikka; Kjell Någren; Jarmo Hietala; Harry Scheinin
Striatal dopamine D2/D3 receptor availability correlates with individual response characteristics to pain.
The European journal of neuroscience 2004;20(6):1587-92.
2004: Jaakko Kalmari; Antti Pertovaara
Colorectal distension-induced suppression of a nociceptive somatic reflex response in the rat: modulation by tissue injury or inflammation.
Brain research 2004;1018(1):106-10.
2004: Heikki Mansikka; Janne Lähdesmäki; Mika Scheinin; Antti Pertovaara
Alpha(2A) adrenoceptors contribute to feedback inhibition of capsaicin-induced hyperalgesia.
Anesthesiology 2004;101(1):185-90.
2004: Ilkka K Martikainen; Matti V Närhi; Antti Pertovaara
Spatial integration of cold pressor pain sensation in humans.
Neuroscience letters 2004;361(1-3):140-3.
2004: Shelley Ylioja; Antti Pertovaara; Juha Koivisto; Antti Korvenoja; Denis Artchakov; Synnöve Carlson
The effect of interstimulus interval on somatosensory point localization.
Somatosensory & motor research 2004;21(1):3-7.
2004: Maija-Liisa Kalliomäki; Antti Pertovaara; Annika Brandt; Hong Wei; Pirjo Pietilä; Jaakko Kalmari; Mei Xu; Eija Kalso; Pertti Panula
Prolactin-releasing peptide affects pain, allodynia and autonomic reflexes through medullary mechanisms.
Neuropharmacology 2004;46(3):412-24.
2004: Antti Pertovaara
Antinociceptive properties of fadolmidine (MPV-2426), a novel alpha2-adrenoceptor agonist.
CNS drug reviews 2004;10(2):117-26.
2003: Janne Lähdesmäki; Mika Scheinin; Antti Pertovaara; Heikki Mansikka
The alpha2A-adrenoceptor subtype is not involved in inflammatory hyperalgesia or morphine-induced antinociception.
European journal of pharmacology 2003;468(3):183-9.
2003: Antti Pertovaara; Hong Wei
A dissociative change in the efficacy of supraspinal versus spinal morphine in the neuropathic rat.
Pain 2003;101(3):237-50.
2003: Sirkku Niissalo; Göran Hampf; Jarkko Hietanen; Maria Malmström; Svetlana Solovieva; Antti Pertovaara; Yrjö T Konttinen
Thermal sensation and pain in oral lichen planus and lichenoid reaction.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2003;32(1):41-5.
2003: Antti Pertovaara; Jaakko Kalmari
Comparison of the visceral antinociceptive effects of spinally administered MPV-2426 (fadolmidine) and clonidine in the rat.
Anesthesiology 2003;98(1):189-94.
2002: Nora Hagelberg; Ilkka K Martikainen; Heikki Mansikka; Susanna Hinkka; Kjell Någren; Jarmo Hietala; Harry Scheinin; Antti Pertovaara
Dopamine D2 receptor binding in the human brain is associated with the response to painful stimulation and pain modulatory capacity.
Pain 2002;99(1-2):273-9.
2002: Ilkka K Martikainen; Antti Pertovaara
Spatial discrimination of one versus two test stimuli in the human skin: dissociation of mechanisms depending on the task and the modality of stimulation.
Neuroscience letters 2002;328(3):322-4.
2002: Antti Pertovaara; Jaakko Kalmari
Neuropathy reduces viscero-somatic inhibition via segmental mechanisms in rats.
Neuroreport 2002;13(8):1047-50.
2002: Tiina J Kauppila; Vesa K Kontinen; Hong Wei; Erkki Jyväsjärvi; Antti Pertovaara
Cutaneous vascular responses evoked by noxious stimulation in rats with the spinal nerve ligation-induced model of neuropathy.
Brain research bulletin 2002;58(1):21-6.
2002: Hong Wei; Erkki Jyväsjärvi; Sirkku Niissalo; Mika Hukkanen; Eero Waris; Yrjö T Konttinen; Antti Pertovaara
The influence of chemical sympathectomy on pain responsivity and alpha 2-adrenergic antinociception in neuropathic animals.
Neuroscience 2002;114(3):655-68.
2002: Heikki Mansikka; Li Zhou; David M Donovan; Antti Pertovaara; Srinivasa N Raja
The role of mu-opioid receptors in inflammatory hyperalgesia and alpha 2-adrenoceptor-mediated antihyperalgesia.
Neuroscience 2002;113(2):339-49.
2001: Antti Pertovaara; Hong Wei
Peripheral effects of morphine in neuropathic rats: role of sympathetic postganglionic nerve fibers.
European journal of pharmacology 2001;429(1-3):139-45.
2001: Hong Wei; Pertti Panula; Antti Pertovaara
Modulation of pain by [1DMe]NPYF, a stable analogue of neuropeptide FF, in neuropathic rats.
Brain research 2001;900(2):234-43.
2001: Jaakko Kalmari; Sirkku Niissalo; Yrjö T Konttinen; Antti Pertovaara
Modulation of visceral nociceptive responses of rat spinal dorsal horn neurons by sympathectomy.
Neuroreport 2001;12(4):797-801.
2001: Antti Pertovaara; Hong Wei; Jaakko Kalmari; Mirja Ruotsalainen
Pain behavior and response properties of spinal dorsal horn neurons following experimental diabetic neuropathy in the rat: modulation by nitecapone, a COMT inhibitor with antioxidant properties.
Experimental neurology 2001;167(2):425-34.
2001: Antti Pertovaara; U Keski-Vakkuri; Jaakko Kalmari; Hong Wei; Pertti Panula
Response properties of neurons in the rostroventromedial medulla of neuropathic rats: attempted modulation of responses by [1DMe]NPYF, a neuropeptide FF analogue.
Neuroscience 2001;105(2):457-68.
2001: Pentti Kemppainen; I Vaalamo; N Leppälä; Antti Pertovaara
Changes in tooth pulpal detection and pain thresholds in relation to jaw movement in man.
Archives of oral biology 2001;46(1):33-7.
2000: T Onttonen; Jaakko Kalmari; Antti Pertovaara
Selective and segmentally restricted antinociception induced by MPV-2426, a novel alpha-2-adrenoceptor agonist, following intrathecal administration in the rat.
Acta anaesthesiologica Scandinavica 2000;44(9):1077-82.
2000: M Xu; Hong Wei; Vesa K Kontinen; Eija Kalso; Antti Pertovaara
The dissociation of sedative from spinal antinociceptive effects following administration of a novel alpha-2-adrenoceptor agonist, MPV-2426, in the locus coeruleus in the rat.
Acta anaesthesiologica Scandinavica 2000;44(6):648-55.
2000: J Mäntyvaara; T Sjöholm; Antti Pertovaara
Perioral and dental perception of mechanical stimulus among subjects with and without awareness of bruxism.
Acta odontologica Scandinavica 2000;58(3):125-8.
2000: T Onttonen; Antti Pertovaara
The mechanical antihyperalgesic effect of intrathecally administered MPV-2426, a novel alpha2 -adrenoceptor agonist, in a rat model of postoperative pain.
Anesthesiology 2000;92(6):1740-5.
2000: Antti Pertovaara; Hong Wei
Attenuation of ascending nociceptive signals to the rostroventromedial medulla induced by a novel alpha2-adrenoceptor agonist, MPV-2426, following intrathecal application in neuropathic rats.
Anesthesiology 2000;92(4):1082-92.
2000: Antti Pertovaara
Plasticity in descending pain modulatory systems.
Progress in brain research 2000;129():231-42.
1999: Heikki Mansikka; Erkki Jyväsjärvi; Antti Pertovaara; Tiina J Kauppila
Allodynia induced by regenerating axons is not positively correlated with degree of autotomy in the rat.
Neuroscience letters 1999;276(2):115-8.
1999: Pertti Panula; Eija Kalso; M Nieminen; Vesa K Kontinen; A Brandt; Antti Pertovaara
Neuropeptide FF and modulation of pain.
Brain research 1999;848(1-2):191-6.
1999: Hong Wei; Antti Pertovaara
MK-801, an NMDA receptor antagonist, in the rostroventromedial medulla attenuates development of neuropathic symptoms in the rat.
Neuroreport 1999;10(14):2933-7.
1999: Hong Wei; Antti Pertovaara
Influence of preemptive treatment with MK-801, an N-methyl-D-aspartate receptor antagonist, on development of neuropathic symptoms induced by spinal nerve ligation in the rat.
Anesthesiology 1999;91(1):313-6.
1999: Antti Pertovaara
The influence of stimulus temperature rise rate, adapting temperature, and stimulus duration on suprathreshold responses evoked by noxious heat in the glabrous skin of the limb. Comparison of neuronal discharge in the rat spinal dorsal horn with human sensations.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1999;126(4):482-94.
1999: Vesa K Kontinen; Tiina J Kauppila; S Paananen; Antti Pertovaara; Eija Kalso
Behavioural measures of depression and anxiety in rats with spinal nerve ligation-induced neuropathy.
Pain 1999;80(1-2):341-6.
1999: Matias Röyttä; Hong Wei; Antti Pertovaara
Spinal nerve ligation-induced neuropathy in the rat: sensory disorders and correlation between histology of the peripheral nerves.
Pain 1999;80(1-2):161-70.
1999: J Mäntyvaara; T Sjöholm; Turkka Kirjavainen; Antti Waltimo; M Iivonen; Pentti Kemppainen; Antti Pertovaara
Altered control of submaximal bite force during bruxism in humans.
European journal of applied physiology and occupational physiology 1999;79(4):325-30.
1998: Hong Wei; Pertti Panula; Antti Pertovaara
A differential modulation of allodynia, hyperalgesia and nociception by neuropeptide FF in the periaqueductal gray of neuropathic rats: interactions with morphine and naloxone.
Neuroscience 1998;86(1):311-9.
1998: Tiina J Kauppila; Vesa K Kontinen; Antti Pertovaara
Influence of spinalization on spinal withdrawal reflex responses varies depending on the submodality of the test stimulus and the experimental pathophysiological condition in the rat.
Brain research 1998;797(2):234-42.
1998: Tiina J Kauppila; Erkki Jyväsjärvi; M M Hämäläinen; Antti Pertovaara
The effect of a selective alpha2-adrenoceptor antagonist on pain behavior of the rat varies, depending on experimental parameters.
Pharmacology, biochemistry, and behavior 1998;59(2):477-85.
1998: Antti Pertovaara; M M Hämäläinen; Tiina J Kauppila; Pertti Panula
Carrageenan-induced changes in spinal nociception and its modulation by the brain stem.
Neuroreport 1998;9(2):351-5.
1998: Tiina J Kauppila; Vesa K Kontinen; Antti Pertovaara
Weight bearing of the limb as a confounding factor in assessment of mechanical allodynia in the rat.
Pain 1998;74(1):55-9.
1998: Antti Pertovaara
A neuronal correlate of secondary hyperalgesia in the rat spinal dorsal horn is submodality selective and facilitated by supraspinal influence.
Experimental neurology 1998;149(1):193-202.
1997: Hong Wei; Antti Pertovaara
Peripherally administered alpha2-adrenoceptor agonist in the modulation of chronic allodynia induced by spinal nerve ligation in the rat.
Anesthesia and analgesia 1997;85(5):1122-7.
1997: Antti Pertovaara; Vesa K Kontinen; Eija Kalso
Chronic spinal nerve ligation induces changes in response characteristics of nociceptive spinal dorsal horn neurons and in their descending regulation originating in the periaqueductal gray in the rat.
Experimental neurology 1997;147(2):428-36.
1997: Tiina J Kauppila; Erkki Jyväsjärvi; S Murtomäki; Heikki Mansikka; Antti Pertovaara; I Virtanen; Päivi Liesi
Use of paper for treatment of a peripheral nerve trauma in the rat.
Neuroreport 1997;8(14):3151-5.
1997: Pentti Kemppainen; Antti Waltimo; Tuomas Waltimo; Mauno Könönen; Antti Pertovaara
Differential effects of noxious conditioning stimulation of the cheek by capsaicin on human sensory and inhibitory masseter reflex responses evoked by tooth pulp stimulation.
Journal of dental research 1997;76(9):1561-8.
1997: Heikki Mansikka; Antti Pertovaara
Submodality-selective hyperalgesia adjacent to partially injured sciatic nerve in the rat is dependent on capsaicin-sensitive afferent fibers and independent of collateral sprouting or a dorsal root reflex.
Brain research bulletin 1997;44(3):237-45.
1997: Heikki Mansikka; Antti Pertovaara
Supraspinal influence on hindlimb withdrawal thresholds and mustard oil-induced secondary allodynia in rats.
Brain research bulletin 1997;42(5):359-65.
1996: Pia Rämä; Ilkka Linnankoski; H Tanila; Antti Pertovaara; Synnöve Carlson
Medetomidine, atipamezole, and guanfacine in delayed response performance of aged monkeys.
Pharmacology, biochemistry, and behavior 1996;55(3):415-22.
1996: Antti Pertovaara; Hong Wei; MM Hämäläinen
Lidocaine in the rostroventromedial medulla and the periaqueductal gray attenuates allodynia in neuropathic rats.
Neuroscience letters 1996;218(2):127-30.
1996: M Grönroos; T Reunala; Antti Pertovaara
Influence of selective nerve fiber blocks on argon laser-induced thermal pain in the human skin.
Neuroscience letters 1996;211(2):143-5.
1996: Heikki Mansikka; Juhana J. Idänpään-Heikkilä; Antti Pertovaara
Different roles of alpha 2-adrenoceptors of the medulla versus the spinal cord in modulation of mustard oil-induced central hyperalgesia in rats.
European journal of pharmacology 1996;297(1-2):19-26.
1996: MM Hämäläinen; Tiina J Kauppila; T Taira; Antti Pertovaara
A noninvasive method for studying quantitatively heat-evoked nocifensive hindlimb withdrawal reflexes in lightly anesthetized rats.
Physiology & behavior 1996;59(2):389-92.
1996: Antti Pertovaara; Tiina J Kauppila; MM Hämäläinen
Influence of skin temperature on heat pain threshold in humans.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1996;107(3):497-503.
1995: Tiina J Kauppila; M Grönroos; Antti Pertovaara
An attempt to attenuate experimental pain in humans by dextromethorphan, an NMDA receptor antagonist.
Pharmacology, biochemistry, and behavior 1995;52(3):641-4.
1995: Ilkka Linnankoski; M Grönroos; Synnöve Carlson; Antti Pertovaara
Effect of cocaine on sexual behaviour in male stumptail macaques (Macaca arctoides).
Pharmacology, biochemistry, and behavior 1995;52(1):211-6.
1995: MM Hämäläinen; Erkki Jyväsjärvi; Antti Pertovaara
Can the alpha 2-adrenoceptor agonist-mediated suppression of nocifensive reflex responses be due to action on motoneurons or peripheral nociceptors?
Neuroscience letters 1995;196(1-2):29-32.
1995: Heikki Mansikka; Antti Pertovaara
Influence of selective alpha 2-adrenergic agents on mustard oil-induced central hyperalgesia in rats.
European journal of pharmacology 1995;281(1):43-8.
1995: T Taira; H Tanila; Erkki Jyväsjärvi; Antti Pertovaara; Tiina J Kauppila
Activation of alpha 2-adrenergic receptors decreases nerve trauma-induced afferent barrage but not autotomy.
Brain research bulletin 1995;36(6):563-7.
1995: Heikki Mansikka; Antti Pertovaara
The role of alpha 2-adrenoceptors of the medullary lateral reticular nucleus in spinal antinociception in rats.
Brain research bulletin 1995;37(6):633-8.
1995: MM Hämäläinen; Antti Pertovaara
The antinociceptive action of an alpha 2-adrenoceptor agonist in the spinal dorsal horn is due to a direct spinal action and not to activation of descending inhibition.
Brain research bulletin 1995;37(6):581-7.
1994: M Grönroos; Hannu Naukkarinen; Antti Pertovaara
Capsaicin-induced central facilitation of a sympathetic vasoconstrictor response to painful stimulation in humans.
Neuroscience letters 1994;182(2):163-6.
1994: Antti Pertovaara; MM Hämäläinen
Spinal potentiation and supraspinal additivity in the antinociceptive interaction between systemically administered alpha 2-adrenoceptor agonist and cocaine in the rat.
Anesthesia and analgesia 1994;79(2):261-6.
1994: M Luukko; Y Konttinen; P Kemppinen; Antti Pertovaara
Influence of various experimental parameters on the incidence of thermal and mechanical hyperalgesia induced by a constriction mononeuropathy of the sciatic nerve in lightly anesthetized rats.
Experimental neurology 1994;128(1):143-54.
1994: Yrjö T Konttinen; P Kemppinen; M Segerberg; Mika Hukkanen; R Rees; Seppo Santavirta; Timo Sorsa; Antti Pertovaara; Julia M Polak
Peripheral and spinal neural mechanisms in arthritis, with particular reference to treatment of inflammation and pain.
Arthritis and rheumatism 1994;37(7):965-82.
1994: R Helminen; Heikki Mansikka; Antti Pertovaara
Lowered or increased cutaneous sensitivity during movement depends on stimulus intensity.
Perceptual and motor skills 1994;78(3 Pt 1):721-2.
1994: Antti Pertovaara; MM Hämäläinen; Tiina J Kauppila; E Mecke; Synnöve Carlson
Dissociation of the alpha 2-adrenergic antinociception from sedation following microinjection of medetomidine into the locus coeruleus in rats.
Pain 1994;57(2):207-15.
1994: Pentti Kemppainen; H Leppänen; Erkki Jyväsjärvi; Antti Pertovaara
Blood flow increase in the orofacial area of humans induced by painful stimulation.
Brain research bulletin 1994;33(6):655-62.
1994: M Grönroos; Antti Pertovaara
A selective suppression of human pain sensitivity by carbon dioxide: central mechanisms implicated.
European journal of applied physiology and occupational physiology 1994;68(1):74-9.
1994: Antti Pertovaara; R R Helminen; Heikki Mansikka
The movement-induced modulation in discriminability between cutaneous nonpainful stimuli depends on test stimulus intensity.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1994;101(3):506-12.
1993: MM Hämäläinen; Antti Pertovaara
The rostroventromedial medulla is not involved in alpha 2-adrenoceptor-mediated antinociception in the rat.
Neuropharmacology 1993;32(12):1411-8.
1993: M Luukko; Antti Pertovaara
Influence of an experimental peripheral mononeuropathy on the responses of medial bulboreticular neurons to noxious skin stimulation and the modulation of the responses by an alpha 2-adrenoceptor agonist in the rat.
Experimental neurology 1993;124(2):390-4.
1993: M Grönroos; Antti Pertovaara
Capsaicin-induced central facilitation of a nociceptive flexion reflex in humans.
Neuroscience letters 1993;159(1-2):215-8.
1993: Antti Pertovaara
Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies.
Progress in neurobiology 1993;40(6):691-709.
1993: Pentti Kemppainen; H Leppänen; Antti Waltimo; Antti Pertovaara
Effects of jaw clenching, jaw movement and static jaw position on facial skin sensitivity to non-painful electrical stimulation in man.
Archives of oral biology 1993;38(4):303-8.
1993: Ilkka Linnankoski; M Grönroos; Antti Pertovaara
Eye contact as a trigger of male sexual arousal in stump-tailed macaques (Macaca arctoides).
Folia primatologica; international journal of primatology 1993;60(3):181-4.
1992: Tiina J Kauppila; E Mecke; Antti Pertovaara
Enhancement of morphine-induced analgesia and attenuation of morphine-induced side-effects by cocaine in rats.
Pharmacology & toxicology 1992;71(3 Pt 1):173-8.
1992: Synnöve Carlson; H Tanila; Pia Rämä; E Mecke; Antti Pertovaara
Effects of medetomidine, an alpha-2 adrenoceptor agonist, and atipamezole, an alpha-2 antagonist, on spatial memory performance in adult and aged rats.
Behavioral and neural biology 1992;58(2):113-9.
1992: Tiina J Kauppila; Erkki Jyväsjärvi; Antti Pertovaara
Effects of atipamezole, an alpha 2-adrenoceptor antagonist, on the anesthesia induced by barbiturates and medetomidine.
Anesthesia and analgesia 1992;75(3):416-20.
1992: Ilkka Linnankoski; M Grönroos; Synnöve Carlson; Antti Pertovaara
Increased sexual behavior in male Macaca arctoides monkeys produced by atipamezole, a selective alpha 2-adrenoceptor antagonist.
Pharmacology, biochemistry, and behavior 1992;42(1):197-200.
1992: T Huopaniemi; Erkki Jyväsjärvi; Synnöve Carlson; F Lindroos; Antti Pertovaara
Response characteristics of tooth pulp-driven postsynaptic neurons in the spinal trigeminal subnucleus oralis of the cat.
Acta physiologica Scandinavica 1992;144(2):177-83.
1992: Antti Pertovaara; Pentti Kemppainen; H Leppänen
Lowered cutaneous sensitivity to nonpainful electrical stimulation during isometric exercise in humans.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1992;89(2):447-52.
1991: Antti Pertovaara
Antinociception in bulboreticular neurons of the rat produced by spinally administered medetomidine, an alpha 2-adrenoceptor agonist.
European journal of pharmacology 1991;204(1):9-14.
1991: Antti Pertovaara; Tiina J Kauppila; E Mecke
An attempted reversal of cocaine-induced analgesia by dexamethasone.
Pharmacology & toxicology 1991;68(2):93-5.
1991: Antti Pertovaara; Pentti Kemppainen; Tiina J Kauppila
The effects of medetomidine, an alpha-2-adrenoceptor agonist, and cocaine on the tooth pulp-evoked jaw-opening reflex in cat.
Pharmacology, biochemistry, and behavior 1991;38(2):287-92.
1991: Antti Pertovaara; E Mecke; Synnöve Carlson
Attempted reversal of cocaine-induced antinociceptive effects with naloxone, an opioid antagonist.
European journal of pharmacology 1991;192(3):349-53.
1991: P Paalasmaa; Pentti Kemppainen; Antti Pertovaara
Modulation of skin sensitivity by dynamic and isometric exercise in man.
European journal of applied physiology and occupational physiology 1991;62(4):279-85.
1991: Tiina J Kauppila; Antti Pertovaara
Effects of different sensory and behavioral manipulations on autotomy caused by a sciatic lesion in rats.
Experimental neurology 1991;111(1):128-30.
1991: Antti Pertovaara; Tiina J Kauppila; Erkki Jyväsjärvi; Eija Kalso
Involvement of supraspinal and spinal segmental alpha-2-adrenergic mechanisms in the medetomidine-induced antinociception.
Neuroscience 1991;44(3):705-14.
1991: Tiina J Kauppila; Pentti Kemppainen; H Tanila; Antti Pertovaara
Effect of systemic medetomidine, an alpha 2 adrenoceptor agonist, on experimental pain in humans.
Anesthesiology 1991;74(1):3-8.
1990: Synnöve Carlson; H Tanila; Antti Pertovaara; A Lähteenmäki
Vertical and horizontal coding of space in the monkey dorsolateral prefrontal cortex.
Brain research 1990;527(1):145-9.
1990: Antti Pertovaara; T Tukeva
Cocaine: effect on spinal projection neurons in the rat.
Brain research bulletin 1990;25(1):1-6.
1990: Pentti Kemppainen; P Paalasmaa; Antti Pertovaara; A Alila; G Johansson
Dexamethasone attenuates exercise-induced dental analgesia in man.
Brain research 1990;519(1-2):329-32.
1990: Antti Pertovaara; Tiina J Kauppila; T Tukeva
The effect of medetomidine, an alpha 2-adrenoceptor agonist, in various pain tests.
European journal of pharmacology 1990;179(3):323-8.
1990: J Kekoni; I Tikkala; Antti Pertovaara; Heikki Hämäläinen
Spatial features of vibrotactile masking effects on airpuff-elicited sensations in the human hand.
Somatosensory & motor research 1990;7(4):353-63.
1989: Antti Pertovaara; T Tukeva
Effect of subcutaneous formalin treatment on responses to bulboreticular nociceptive neurons in the rat.
Brain research bulletin 1989;23(6):457-62.
1989: Antti Pertovaara; Tiina J Kauppila
Effect of chronic sciatic nerve section on saphenous nerve input to midline bulboreticular formation in the rat.
Neuroscience letters 1989;105(1-2):68-72.
1989: Synnöve Carlson; H Tanila; Ilkka Linnankoski; Antti Pertovaara; A Kehr
Comparison of tactile discrimination ability of visually deprived and normal monkeys.
Acta physiologica Scandinavica 1989;135(3):405-10.
1988: T Huopaniemi; Antti Pertovaara; Erkki Jyväsjärvi; Synnöve Carlson
Effect of naloxone on tooth pulp-evoked jaw-opening reflex in the barbiturate-anaesthetized cat.
Acta physiologica Scandinavica 1988;134(3):327-31.
1987: Antti Pertovaara; T Huopaniemi; Synnöve Carlson; Erkki Jyväsjärvi
Response characteristics of tooth pulp-driven postsynaptic neurons in the spinal trigeminal subnucleus interpolaris of the cat: comparison with primary afferent fiber, subnucleus caudalis, reflex, and sensory responses.
Brain research 1987;422(2):205-17.
1987: A S Virtanen; T Huopaniemi; M V Närhi; Antti Pertovaara; K Wallgren
The effect of temporal parameters on subjective sensations evoked by electrical tooth stimulation.
Pain 1987;30(3):361-71.
1987: Pentti Kemppainen; Antti Pertovaara; T Huopaniemi; O Hämäläinen; M Grönblad
Human pain thresholds after the application of lypressin, a vasopressin analogue.
Pharmacology & toxicology 1987;61(1):16-9.
1987: Synnöve Carlson; Antti Pertovaara; H Tanila
Late effects of early binocular visual deprivation on the function of Brodmann's area 7 of monkeys (Macaca arctoides).
Brain research 1987;430(1):101-11.
1987: Antti Pertovaara; T Huopaniemi; K Aukee; Synnöve Carlson
Tooth pulp-evoked activity in the spinal trigeminal nucleus caudalis of cat: comparison to primary afferent fiber, reflex, and sensory responses.
Experimental neurology 1987;95(1):155-66.
1987: J Kekoni; Antti Pertovaara; Heikki Hämäläinen
Vibrotactile masking effects on airpuff-elicited sensations vary with skin region in the human hand.
Somatosensory research 1987;5(2):93-105.
1987: Antti Pertovaara; Pentti Kemppainen; T Huopaniemi; G Johansson
Pain and stress: correlation of stress hormone release to pain modulation in man.
Annals of clinical research 1987;19(2):83-6.
1986: Pentti Kemppainen; Antti Pertovaara; T Huopaniemi; G Johansson
Elevation of dental pain threshold induced in man by physical exercise is not reversed by cyproheptadine-mediated suppression of growth hormone release.
Neuroscience letters 1986;70(3):388-92.
1986: Antti Pertovaara; T Huopaniemi; K Aukee
Tooth pulp-evoked jaw-opening reflex in the cat: evidence for central facilitation induced by noxious discharge in the intradental nerve fibers.
Experimental neurology 1986;92(1):207-19.
1985: Pentti Kemppainen; Antti Pertovaara; T Huopaniemi; G Johansson; S L Karonen
Modification of dental pain and cutaneous thermal sensitivity by physical exercise in man.
Brain research 1985;360(1-2):33-40.
1984: Antti Pertovaara; T Huopaniemi; A Virtanen; G Johansson
The influence of exercise on dental pain thresholds and the release of stress hormones.
Physiology & behavior 1984;33(6):923-6.
1982: Antti Pertovaara; Pentti Kemppainen; G Johansson; S L Karonen
Ischemic pain nonsegmentally produces a predominant reduction of pain and thermal sensitivity in man: a selective role for endogenous opioids.
Brain research 1982;251(1):83-92.
1982: Antti Pertovaara; Pentti Kemppainen; G Johansson; S L Karonen
Dental analgesia produced by non-painful low-frequency stimulation is not influenced by stress or reversed by naloxone.
Pain 1982;13(4):379-84.