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Richard Pestell
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69
Lisanti, Michael
54
Wang, Chenguang
41
Albanese, Chris
37
Fu, Maofu
22
Wu, Kongming
20
Sotgia, Federica
18
Bouzahzah, Boumediene
17
Li, Zhiping
14
Casimiro, Mathew
13
Liu, Manran
12
Mercier, Isabelle
12
Hulit, James
12
Jiao, Xuanmao
12
Frank, Philippe
12
Di Vizio, Dolores
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All Publications
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2009: Genander Maria; Halford Michael M; Xu Nan-Jie; Eriksson Malin; Yu Zuoren; Qiu Zhaozhu; Martling Anna; Greicius Gedas; Thakar Sonal; Catchpole Timothy; Chumley Michael J; Zdunek Sofia; Wang Chenguang; Holm Torbjörn; Goff Stephen P; Pettersson Sven; Pestell Richard G; Henkemeyer Mark; Frisén Jonas
Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression.
Cell 2009;139(4):679-92.
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2009: Liu Manran; Casimiro Mathew C; Wang Chenguang; Shirley L Andrew; Jiao Xuanmao; Katiyar Sanjay; Ju Xiaoming; Li Zhiping; Yu Zuoren; Zhou Jie; Johnson Michael; Fortina Paolo; Hyslop Terry; Windle Jolene J; Pestell Richard G
p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(45):19035-9.
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2009: Zhou Jie; Zhang Wei; Liang Bing; Casimiro Mathew C; Whitaker-Menezes Diana; Wang Min; Lisanti Michael P; Lanza-Jacoby Susan; Pestell Richard G; Wang Chenguang
PPARgamma activation induces autophagy in breast cancer cells.
The international journal of biochemistry & cell biology 2009;41(11):2334-42.
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2009: Di Vizio Dolores; Morello Matteo; Sotgia Federica; Pestell Richard G; Freeman Michael R; Lisanti Michael P
An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation.
Cell cycle (Georgetown, Tex.) 2009;8(15):2420-4.
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2009: Nan Fangfang; Lü Qingtao; Zhou Jie; Cheng Lei; Popov Vladimir M; Wei Shuangyan; Kong Beihua; Pestell Richard G; Lisanti Michael P; Jiang Jie; Wang Chenguang
Altered expression of DACH1 and cyclin D1 in endometrial cancer.
Cancer biology & therapy 2009;8(16):1534-9.
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2009: Popov Vladimir M; Zhou Jie; Shirley L Andrew; Quong Judy; Yeow Wen-Shuz; Wright Jennifer A; Wu Kongming; Rui Hallgeir; Vadlamudi Ratna K; Jiang Jie; Kumar Rakesh; Wang Chenguang; Pestell Richard G
The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling.
Cancer research 2009;69(14):5752-60.
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2009: Witkiewicz Agnieszka K; Dasgupta Abhijit; Nguyen Katherine H; Liu Chengbao; Kovatich Albert J; Schwartz Gordon F; Pestell Richard G; Sotgia Federica; Rui Hallgeir; Lisanti Michael P
Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer.
Cancer biology & therapy 2009;8(11):1071-9.
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2009: Witkiewicz Agnieszka K; Casimiro Mathew C; Dasgupta Abhijit; Mercier Isabelle; Wang Chenguang; Bonuccelli Gloria; Jasmin Jean-François; Frank Philippe G; Pestell Richard G; Kleer Celina G; Sotgia Federica; Lisanti Michael P
Towards a new "stromal-based" classification system for human breast cancer prognosis and therapy.
Cell cycle (Georgetown, Tex.) 2009;8(11):1654-8.
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2009: Witkiewicz Agnieszka K; Dasgupta Abhijit; Sotgia Federica; Mercier Isabelle; Pestell Richard G; Sabel Michael; Kleer Celina G; Brody Jonathan R; Lisanti Michael P
An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers.
The American journal of pathology 2009;174(6):2023-34.
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2009: Mercier Isabelle; Jasmin Jean-Francois; Pavlides Stephanos; Minetti Carlo; Flomenberg Neal; Pestell Richard G; Frank Philippe G; Sotgia Federica; Lisanti Michael P
Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders.
Laboratory investigation; a journal of technical methods and pathology 2009;89(6):614-23.
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2009: Bonuccelli Gloria; Casimiro Mathew C; Sotgia Federica; Wang Chenguang; Liu Manran; Katiyar Sanjay; Zhou Jie; Dew Elliott; Capozza Franco; Daumer Kristin M; Minetti Carlo; Milliman Janet N; Alpy Fabien; Rio Marie-Christine; Tomasetto Catherine; Mercier Isabelle; Flomenberg Neal; Frank Philippe G; Pestell Richard G; Lisanti Michael P
Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.
The American journal of pathology 2009;174(5):1650-62.
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2009: Liu Manran; Ju Xiaoming; Willmarth Nicole E; Casimiro Mathew C; Ojeifo John; Sakamaki Toshiyuki; Katiyar Sanjay; Jiao Xuanmao; Popov Vladimir M; Yu Zuoren; Wu Kongming; Joyce David; Wang Chenguang; Pestell Richard G
Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo.
The American journal of pathology 2009;174(5):1910-20.
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2009: Mercier Isabelle; Bryant Kelly G; Sotgia Federica; Bonuccelli Gloria; Witkiewicz Agnieszka K; Dasgupta Abhijit; Jasmin Jean-François; Pestell Richard G; Lisanti Michael P
Using Caveolin-1 epithelial immunostaining patterns to stratify human breast cancer patients and predict the Caveolin-1 (P132L) mutation.
Cell cycle (Georgetown, Tex.) 2009;8(9):1396-401.
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2009: Wu Kongming; Katiyar Sanjay; Witkiewicz Agnes; Li Anping; McCue Peter; Song Liang-Nian; Tian Lifeng; Jin Ming; Pestell Richard G
The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth.
Cancer research 2009;69(8):3347-55.
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2009: Mercier Isabelle; Casimiro Mathew C; Zhou Jie; Wang Chenguang; Plymire Christopher; Bryant Kelly G; Daumer Kristin M; Sotgia Federica; Bonuccelli Gloria; Witkiewicz Agnieszka K; Lin Justin; Tran Thai Hong; Milliman Janet; Frank Philippe G; Jasmin Jean-François; Rui Hallgeir; Pestell Richard G; Lisanti Michael P
Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions.
The American journal of pathology 2009;174(4):1172-90.
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2009: Velasco-Velázquez Marco A; Yu Zuoren; Jiao Xuanmao; Pestell Richard G
Cancer stem cells and the cell cycle: targeting the drive behind breast cancer.
Expert review of anticancer therapy 2009;9(3):275-9.
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2009: Marampon Francesco; Bossi Gianluca; Ciccarelli Carmela; Di Rocco Agnese; Sacchi Ada; Pestell Richard G; Zani Bianca M
MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.
Molecular cancer therapeutics 2009;8(3):543-51.
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2009: Sotgia Federica; Del Galdo Francesco; Casimiro Mathew C; Bonuccelli Gloria; Mercier Isabelle; Whitaker-Menezes Diana; Daumer Kristin M; Zhou Jie; Wang Chenguang; Katiyar Sanjay; Xu Huan; Bosco Emily; Quong Andrew A; Aronow Bruce; Witkiewicz Agnieszka K; Minetti Carlo; Frank Philippe G; Jimenez Sergio A; Knudsen Erik S; Pestell Richard G; Lisanti Michael P
Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts.
The American journal of pathology 2009;174(3):746-61.
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2009: Sotgia Federica; Casimiro Mathew C; Bonuccelli Gloria; Liu Manran; Whitaker-Menezes Diana; Er Ozlem; Daumer Kristin M; Mercier Isabelle; Witkiewicz Agnieszka K; Minetti Carlo; Capozza Franco; Gormley Michael; Quong Andrew A; Rui Hallgeir; Frank Philippe G; Milliman Janet N; Knudsen Erik S; Zhou Jie; Wang Chenguang; Pestell Richard G; Lisanti Michael P
Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation.
The American journal of pathology 2009;174(2):613-29.
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2008: Augustus Ayanna S; Buchanan Jonathan; Gutman Ellen; Rengo Giuseppe; Pestell Richard G; Fortina Paolo; Koch Walter J; Bensadoun Andre; Abel E Dale; Lisanti Michael P
Hearts lacking caveolin-1 develop hypertrophy with normal cardiac substrate metabolism.
Cell cycle (Georgetown, Tex.) 2008;7(16):2509-18.
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2008: Yu Zuoren; Wang Chenguang; Wang Min; Li Zhiping; Casimiro Mathew C; Liu Manran; Wu Kongming; Whittle James; Ju Xiaoming; Hyslop Terry; McCue Peter; Pestell Richard G
A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation.
The Journal of cell biology 2008;182(3):509-17.
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2008: Augustus Ayanna S; Buchanan Jonathan; Addya Sankar; Rengo Giuseppe; Pestell Richard G; Fortina Paolo; Koch Walter J; Bensadoun Andre; Abel E Dale; Lisanti Michael P
Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts.
American journal of physiology. Heart and circulatory physiology 2008;295(2):H657-66.
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2008: Mercier Isabelle; Casimiro Mathew C; Wang Chenguang; Rosenberg Anne L; Quong Judy; Minkeu Alimatou; Allen Kathleen G; Danilo Christiane; Sotgia Federica; Bonuccelli Gloria; Jasmin Jean-François; Xu Huan; Bosco Emily; Aronow Bruce; Witkiewicz Agnieszka; Pestell Richard G; Knudsen Erik S; Lisanti Michael P
Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy.
Cancer biology & therapy 2008;7(8):1212-25.
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2008: Pezo Rossanna C; Gandhi Saumil J; Shirley L Andrew; Pestell Richard G; Augenlicht Leonard H; Singer Robert H
Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors.
Cancer research 2008;68(13):4977-82.
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2008: Mercier Isabelle; Vuolo Magalis; Jasmin Jean-Francois; Medina Christina M; Williams Mark; Mariadason John M; Qian Hong; Xue Xiaonan; Pestell Richard G; Lisanti Michael P; Kitsis Richard N
ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer.
Cell cycle (Georgetown, Tex.) 2008;7(11):1640-7.
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2008: Marampon Francesco; Casimiro Mathew C; Fu Maofu; Powell Michael J; Popov Vladimir M; Lindsay Jaime; Zani Bianca M; Ciccarelli Carmela; Watanabe Genichi; Lee Richard J; Pestell Richard G
Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB.
Molecular biology of the cell 2008;19(6):2566-78.
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2008: Wu Kongming; Katiyar Sanjay; Li Anping; Liu Manran; Ju Xiaoming; Popov Vladimir M; Jiao Xuanmao; Lisanti Michael P; Casola Antonella; Pestell Richard G
Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):6924-9.
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2008: Jiao Xuanmao; Katiyar Sanjay; Liu Manran; Mueller Susette C; Lisanti Michael P; Li Anping; Pestell Timothy G; Wu Kongming; Ju Xiaoming; Li Zhiping; Wagner Erwin F; Takeya Tatsuo; Wang Chenguang; Pestell Richard G
Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase.
Molecular biology of the cell 2008;19(4):1378-90.
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2008: Sundaram Kumaran; Mani Santhosh K; Kitatani Kazuyuki; Wu Kongming; Pestell Richard G; Reddy Sakamuri V
DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells.
Journal of cellular biochemistry 2008;103(6):1747-59.
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2008: Rao Mahadev; Casimiro Mathew C; Lisanti Michael P; D'Amico Mark; Wang Chenguang; Shirley L Andrew; Leader Jennifer E; Liu Manran; Stallcup Michael; Engel Daniel A; Murphy Daniel J; Pestell Richard G
Inhibition of cyclin D1 gene transcription by Brg-1.
Cell cycle (Georgetown, Tex.) 2008;7(5):647-55.
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2008: Li Zhiping; Wang Chenguang; Jiao Xuanmao; Katiyar Sanjay; Casimiro Mathew C; Prendergast George C; Powell Michael J; Pestell Richard G
Alternate cyclin D1 mRNA splicing modulates p27KIP1 binding and cell migration.
The Journal of biological chemistry 2008;283(11):7007-15.
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2008: Wang Chenguang; Powell Michael J; Popov Vladimir M; Pestell Richard G
Acetylation in nuclear receptor signaling and the role of sirtuins.
Molecular endocrinology (Baltimore, Md.) 2008;22(3):539-45.
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2008: Bouzahzah Boumediene; Yurchenko Vyacheslav; Nagajyothi Fnu; Hulit James; Sadofsky Moshe; Braunstein Vicki L; Mukherjee Shankar; Weiss Hannah; Machado Fabiana S; Pestell Richard G; Lisanti Michael P; Tanowitz Herbert B; Albanese Chris
Regulation of host cell cyclin D1 by Trypanosoma cruzi in myoblasts.
Cell cycle (Georgetown, Tex.) 2008;7(4):500-3.
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2007: Whittle James R; Powell Michael J; Popov Vladimir M; Shirley L Andrew; Wang Chenguang; Pestell Richard G
Sirtuins, nuclear hormone receptor acetylation and transcriptional regulation.
Trends in endocrinology and metabolism: TEM 2007;18(9):356-64.
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2007: Yao Dachun; Taguchi Tetsuya; Matsumura Takeshi; Pestell Richard; Edelstein Diane; Giardino Ida; Suske Guntram; Rabbani Naila; Thornalley Paul J; Sarthy Vijay P; Hammes Hans-Peter; Brownlee Michael
High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.
The Journal of biological chemistry 2007;282(42):31038-45.
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2007: Fernando Romaine; Foster James S; Bible Amber; Ström Anders; Pestell Richard G; Rao Mahadev; Saxton Arnold; Baek Seung Joon; Yamaguchi Kiyoshi; Donnell Robert; Cekanova Maria; Wimalasena Jay
Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1.
The Journal of biological chemistry 2007;282(39):28864-73.
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2007: Di Vizio Dolores; Sotgia Federica; Williams Terence M; Hassan Ghada S; Capozza Franco; Frank Philippe G; Pestell Richard G; Loda Massimo; Freeman Michael R; Lisanti Michael P
Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression.
Cancer biology & therapy 2007;6(8):1263-8.
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2007: Avvisato Christopher L; Yang Xiang; Shah Salim; Hoxter Becky; Li Weiqun; Gaynor Richard; Pestell Richard; Tozeren Aydin; Byers Stephen W
Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells.
Journal of cell science 2007;120(Pt 15):2672-82.
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2007: Casimiro Mathew; Rodriguez Olga; Pootrakul Llana; Aventian Maral; Lushina Nadia; Cromelin Caroline; Ferzli Georgina; Johnson Kevin; Fricke Stanley; Diba Fantahun; Kallakury Bhaskar; Ohanyerenwa Chioma; Chen Maxine; Ostrowski Michael; Hung Mien-Chie; Rabbani Shafaat A; Datar Ram; Cote Richard; Pestell Richard; Albanese Chris
ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo.
Cancer research 2007;67(9):4364-72.
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2007: Ju Xiaoming; Katiyar Sanjay; Wang Chenguang; Liu Manran; Jiao Xuanmao; Li Shengwen; Zhou Jie; Turner Jacob; Lisanti Michael P; Russell Robert G; Mueller Susette C; Ojeifo John; Chen William S; Hay Nissim; Pestell Richard G
Akt1 governs breast cancer progression in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7438-43.
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2007: Ozaki Iwata; Zhang Hao; Mizuta Toshihiko; Ide Yasushi; Eguchi Yuichiro; Yasutake Tsutomu; Sakamaki Toshiyuki; Pestell Richard G; Yamamoto Kyosuke
Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor kappaB activation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):2236-45.
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2007: Wu Kongming; Liu Manran; Li Anping; Donninger Howard; Rao Mahadev; Jiao Xuanmao; Lisanti Michael P; Cvekl Ales; Birrer Michael; Pestell Richard G
Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
Molecular biology of the cell 2007;18(3):755-67.
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2007: Yao Dachun; Taguchi Tetsuya; Matsumura Takeshi; Pestell Richard; Edelstein Diane; Giardino Ida; Suske Guntram; Ahmed Naila; Thornalley Paul J; Sarthy Vijay P; Hammes Hans-Peter; Brownlee Michael
Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription.
Cell 2007;128(3):625.
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2007: Popov Vladimir M; Wang Chenguang; Shirley L Andrew; Rosenberg Anne; Li Shengwen; Nevalainen Marja; Fu Maofu; Pestell Richard G
The functional significance of nuclear receptor acetylation.
Steroids 2007;72(2):221-30.
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2007: Katiyar Sanjay; Jiao Xuanmao; Wagner Erwin; Lisanti Michael P; Pestell Richard G
Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.
Molecular and cellular biology 2007;27(4):1356-69.
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2007: Pavithra Lakshminarasimhan; Rampalli Shravanti; Sinha Surajit; Sreenath Kadreppa; Pestell Richard G; Chattopadhyay Samit
Stabilization of SMAR1 mRNA by PGA2 involves a stem loop structure in the 5' UTR.
Nucleic acids research 2007;35(18):6004-16.
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2006: Medina Freddy A; de Almeida Cecilia J; Dew Elliott; Li Jiangwei; Bonuccelli Gloria; Williams Terence M; Cohen Alex W; Pestell Richard G; Frank Philippe G; Tanowitz Herbert B; Lisanti Michael P
Caveolin-1-deficient mice show defects in innate immunity and inflammatory immune response during Salmonella enterica serovar Typhimurium infection.
Infection and immunity 2006;74(12):6665-74.
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2006: Leader Jennifer E; Wang Chenguang; Popov Vladimir M; Fu Maofu; Pestell Richard G
Epigenetics and the estrogen receptor.
Annals of the New York Academy of Sciences 2006;1089():73-87.
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2006: Sotgia Federica; Rui Hallgeir; Bonuccelli Gloria; Mercier Isabelle; Pestell Richard G; Lisanti Michael P
Caveolin-1, mammary stem cells, and estrogen-dependent breast cancers.
Cancer research 2006;66(22):10647-51.
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2006: Li Zhiping; Wang Chenguang; Prendergast George C; Pestell Richard G
Cyclin D1 functions in cell migration.
Cell cycle (Georgetown, Tex.) 2006;5(21):2440-2.
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2006: Williams Terence M; Sotgia Federica; Lee Hyangkyu; Hassan Ghada; Di Vizio Dolores; Bonuccelli Gloria; Capozza Franco; Mercier Isabelle; Rui Hallgeir; Pestell Richard G; Lisanti Michael P
Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells.
The American journal of pathology 2006;169(5):1784-801.
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2006: Fu Maofu; Liu Manran; Sauve Anthony A; Jiao Xuanmao; Zhang Xueping; Wu Xiaofang; Powell Michael J; Yang Tianle; Gu Wei; Avantaggiati Maria Laura; Pattabiraman Nagarajan; Pestell Timothy G; Wang Fang; Quong Andrew A; Wang Chenguang; Pestell Richard G
Hormonal control of androgen receptor function through SIRT1.
Molecular and cellular biology 2006;26(21):8122-35.
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2006: Leader Jennifer E; Wang Chenguang; Fu Maofu; Pestell Richard G
Epigenetic regulation of nuclear steroid receptors.
Biochemical pharmacology 2006;72(11):1589-96.
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2006: Chang Ya-Jen; Wu Ming-Shiang; Lin Jaw-Town; Pestell Richard G; Blaser Martin J; Chen Ching-Chow
Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle.
Cellular microbiology 2006;8(11):1740-52.
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2006: Bouzahzah Boumediene; Nagajyothi Fnu; Desruisseaux Mahalia S; Krishnamachary Mohan; Factor Stephen M; Cohen Alex W; Lisanti Michael P; Petkova Stefka B; Pestell Richard G; Wittner Murray; Mukherjee Shankar; Weiss Louis M; Jelicks Linda A; Albanese Chris; Tanowitz Herbert B
Cell cycle regulatory proteins in the liver in murine Trypanosoma cruzi infection.
Cell cycle (Georgetown, Tex.) 2006;5(20):2396-400.
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2006: Li Zhiping; Jiao Xuanmao; Wang Chenguang; Ju Xiaoming; Lu Yinan; Yuan Liangping; Lisanti Michael P; Katiyar Sanjay; Pestell Richard G
Cyclin D1 induction of cellular migration requires p27(KIP1).
Cancer research 2006;66(20):9986-94.
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2006: Wu Kongming; Li Anping; Rao Mahadev; Liu Manran; Dailey Vernon; Yang Ying; Di Vizio Dolores; Wang Chenguang; Lisanti Michael P; Sauter Guido; Russell Robert G; Cvekl Ales; Pestell Richard G
DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth.
Molecular and cellular biology 2006;26(19):7116-29.
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2006: Hulit James; Lee Richard J; Li Zhiping; Wang Chenguang; Katiyar Sanjay; Yang Jianguo; Quong Andrew A; Wu Kongming; Albanese Chris; Russell Robert; Di Vizio Dolores; Koff Andrew; Thummala Saiinder; Zhang Hui; Harrell Jennifer; Sun Hong; Muller William J; Inghirami Giorgio; Lisanti Michael P; Pestell Richard G
p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.
Cancer research 2006;66(17):8529-41.
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2006: Sunde Jan S; Donninger Howard; Wu Kongming; Johnson Michael E; Pestell Richard G; Rose G Scott; Mok Samuel C; Brady John; Bonome Tomas; Birrer Michael J
Expression profiling identifies altered expression of genes that contribute to the inhibition of transforming growth factor-beta signaling in ovarian cancer.
Cancer research 2006;66(17):8404-12.
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2006: Cui Yukun; Niu Airu; Pestell Richard; Kumar Rakesh; Curran Edward M; Liu Yunde; Fuqua Suzanne A W
Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells.
Molecular endocrinology (Baltimore, Md.) 2006;20(9):2020-35.
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2006: Pestell Richard G; Li Zhiping
Antisense to cyclin D1 inhibits VEGF-stimulated growth of vascular endothelial cells: implication of tumor vascularization.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(15):4459-62.
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2006: Stahl Mark; Ge Changhui; Shi Shaolin; Pestell Richard G; Stanley Pamela
Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1.
Cancer research 2006;66(15):7562-70.
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2006: Wang Chenguang; Li Zhiping; Lu Yinan; Du Runlei; Katiyar Sanjay; Yang Jianguo; Fu Maofu; Leader Jennifer E; Quong Andrew; Novikoff Phyllis M; Pestell Richard G
Cyclin D1 repression of nuclear respiratory factor 1 integrates nuclear DNA synthesis and mitochondrial function.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(31):11567-72.
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2006: Sakamaki Toshiyuki; Casimiro Mathew C; Ju Xiaoming; Quong Andrew A; Katiyar Sanjay; Liu Manran; Jiao Xuanmao; Li Anping; Zhang Xueping; Lu Yinan; Wang Chenguang; Byers Stephen; Nicholson Robert; Link Todd; Shemluck Melvin; Yang Jianguo; Fricke Stanley T; Novikoff Phyllis M; Papanikolaou Alexandros; Arnold Andrew; Albanese Christopher; Pestell Richard
Cyclin D1 determines mitochondrial function in vivo.
Molecular and cellular biology 2006;26(14):5449-69.
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2006: Yang Tianle; Fu Maofu; Pestell Richard; Sauve Anthony A
SIRT1 and endocrine signaling.
Trends in endocrinology and metabolism: TEM 2006;17(5):186-91.
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2006: Li Tianhong; Sotgia Federica; Vuolo Magalis A; Li Maomi; Yang Wan Cai; Pestell Richard G; Sparano Joseph A; Lisanti Michael P
Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status.
The American journal of pathology 2006;168(6):1998-2013.
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2006: Li Zhiping; Wang Chenguang; Jiao Xuanmao; Lu Yinan; Fu Maofu; Quong Andrew A; Dye Chip; Yang Jianguo; Dai Maozheng; Ju Xiaoming; Zhang Xueping; Li Anping; Burbelo Peter; Stanley E Richard; Pestell Richard G
Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling.
Molecular and cellular biology 2006;26(11):4240-56.
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2006: Knights Chad D; Catania Jason; Di Giovanni Simone; Muratoglu Selen; Perez Ricardo; Swartzbeck Amber; Quong Andrew A; Zhang Xiaojing; Beerman Terry; Pestell Richard G; Avantaggiati Maria Laura
Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.
The Journal of cell biology 2006;173(4):533-44.
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2006: Yang Ying; Stopka Tomás; Golestaneh Nady; Wang Yan; Wu Kongming; Li Anping; Chauhan Bharesh K; Gao Chun Y; Cveklová Kveta; Duncan Melinda K; Pestell Richard G; Chepelinsky Ana B; Skoultchi Arthur I; Cvekl Ales
Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin.
The EMBO journal 2006;25(10):2107-18.
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2006: Seki Yosuke; Yamamoto Hirofumi; Ngan Chew Yee; Yasui Masayoshi; Tomita Naruya; Kitani Kotaro; Takemasa Ichiro; Ikeda Masataka; Sekimoto Mitsugu; Matsuura Nariaki; Albanese Chris; Kaneda Yasufumi; Pestell Richard G; Monden Morito
Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway.
Molecular cancer therapeutics 2006;5(4):985-94.
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2006: Pestell Richard
Remembering team science is for the patients.
Cancer biology & therapy 2006;5(4):449-52.
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2006: Leslie Kenneth; Lang Cynthia; Devgan Geeta; Azare Janeen; Berishaj Marjan; Gerald William; Kim Young Bae; Paz Keren; Darnell James E; Albanese Christopher; Sakamaki Toshiyuki; Pestell Richard; Bromberg Jacqueline
Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3.
Cancer research 2006;66(5):2544-52.
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2006: Sourisseau Tony; Georgiadis Anastasios; Tsapara Anna; Ali Robin R; Pestell Richard; Matter Karl; Balda Maria S
Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA.
Molecular and cellular biology 2006;26(6):2387-98.
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2006: Sotgia Federica; Schubert William; Pestell Richard G; Lisanti Michael P
Genetic ablation of caveolin-1 in mammary epithelial cells increases milk production and hyper-activates STAT5a signaling.
Cancer biology & therapy 2006;5(3):292-7.
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2006: Yin Yuzhi; Yuan Hongyan; Wang Chenguang; Pattabiraman Nagarajan; Rao Mahadev; Pestell Richard G; Glazer Robert I
3-phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor-gamma and promotes adipocyte differentiation.
Molecular endocrinology (Baltimore, Md.) 2006;20(2):268-78.
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2006: Yao Dachun; Taguchi Tetsuya; Matsumura Takeshi; Pestell Richard; Edelstein Diane; Giardino Ida; Suske Guntram; Ahmed Naila; Thornalley Paul J; Sarthy Vijay P; Hammes Hans-Peter; Brownlee Michael
Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription.
Cell 2006;124(2):275-86.
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2006: Sotgia Federica; Williams Terence M; Schubert William; Medina Freddy; Minetti Carlo; Pestell Richard G; Lisanti Michael P
Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness.
The American journal of pathology 2006;168(1):292-309.
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2006: Hassan Ghada S; Mukherjee Shankar; Nagajyothi Fnu; Weiss Louis M; Petkova Stefka B; de Almeida Cecilia J; Huang Huan; Desruisseaux Mahalia S; Bouzahzah Boumediene; Pestell Richard G; Albanese Chris; Christ George J; Lisanti Michael P; Tanowitz Herbert B
Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells.
Infection and immunity 2006;74(1):152-9.
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2006: Katiyar Pragati; Ma Yongxian; Fan Saijun; Pestell Richard G; Furth Priscilla A; Rosen Eliot M
Regulation of progesterone receptor signaling by BRCA1 in mammary cancer.
Nuclear receptor signaling 2006;4():e006.
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2005: Li Jiangwei; Hassan Ghada S; Williams Terence M; Minetti Carlo; Pestell Richard G; Tanowitz Herbert B; Frank Philippe G; Sotgia Federica; Lisanti Michael P
Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation.
Cell cycle (Georgetown, Tex.) 2005;4(12):1817-25.
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2005: Sotgia Federica; Williams Terence M; Cohen Alex W; Minetti Carlo; Pestell Richard G; Lisanti Michael P
Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling.
Cell cycle (Georgetown, Tex.) 2005;4(12):1808-16.
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2005: Xiao Dongmei; Chinnappan Dharmaraj; Pestell Richard; Albanese Christopher; Weber Horst Christian
Bombesin regulates cyclin D1 expression through the early growth response protein Egr-1 in prostate cancer cells.
Cancer research 2005;65(21):9934-42.
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2005: Giampuzzi Monia; Oleggini Roberta; Albanese Chris; Pestell Richard; Di Donato Armando
beta-catenin signaling and regulation of cyclin D1 promoter in NRK-49F cells transformed by down-regulation of the tumor suppressor lysyl oxidase.
Biochimica et biophysica acta 2005;1745(3):370-81.
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2005: Wang Chenguang; Fan Saijun; Li Zhiping; Fu Maofu; Rao Mahadev; Ma Yongxian; Lisanti Michael P; Albanese Chris; Katzenellenbogen Benita S; Kushner Peter J; Weber Barbara; Rosen Eliot M; Pestell Richard G
Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity.
Cancer research 2005;65(15):6557-67.
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2005: Wu Kongming; D'Amico Mark; Wang Chenguang; Albanese Chris; Pestell Richard G; Mani Sridhar
A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines.
Investigational new drugs 2005;23(4):299-309.
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2005: Fu Maofu; Wang Chenguang; Rao Mahadev; Wu Xiaofang; Bouras Toula; Zhang Xueping; Li Zhiping; Jiao Xuanmao; Yang Jianguo; Li Anping; Perkins Neil D; Thimmapaya Bayar; Kung Andrew L; Munoz Alberto; Giordano Antonio; Lisanti Michael P; Pestell Richard G
Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism.
The Journal of biological chemistry 2005;280(33):29728-42.
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2005: Williams Terence M; Hassan Ghada S; Li Jiangwei; Cohen Alex W; Medina Freddy; Frank Philippe G; Pestell Richard G; Di Vizio Dolores; Loda Massimo; Lisanti Michael P
Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice.
The Journal of biological chemistry 2005;280(26):25134-45.
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2005: Ho Yuan-Soon; Chen Chien-Ho; Wang Ying-Jan; Pestell Richard G; Albanese Chris; Chen Rong-Jane; Chang Mei-Chi; Jeng Jiiang-Huei; Lin Shyr-Yi; Liang Yu-Chih; Tseng How; Lee Wen-Sen; Lin Jen-Kun; Chu Jan-Show; Chen Li-Ching; Lee Chia-Hwa; Tso Wei-Ling; Lai Yann-Chwen; Wu Chih-Hsiung
Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation.
Toxicology and applied pharmacology 2005;205(2):133-48.
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2005: Iyengar Puneeth; Espina Virginia; Williams Terence W; Lin Ying; Berry David; Jelicks Linda A; Lee Hyangkyu; Temple Karla; Graves Reed; Pollard Jeffrey; Chopra Neeru; Russell Robert G; Sasisekharan Ram; Trock Bruce J; Lippman Marc; Calvert Valerie S; Petricoin Emanuel F; Liotta Lance; Dadachova Ekaterina; Pestell Richard G; Lisanti Michael P; Bonaldo Paolo; Scherer Philipp E
Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment.
The Journal of clinical investigation 2005;115(5):1163-76.
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2005: Song D H; Kaufman J C; Borodyansky L; Albanese C; Pestell R G; Wolfe M Michael
Gastrin stabilises beta-catenin protein in mouse colorectal cancer cells.
British journal of cancer 2005;92(8):1581-7.
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2005: Fu Maofu; Rao Mahadev; Bouras Toula; Wang Chenguang; Wu Kongming; Zhang Xueping; Li Zhiping; Yao Tso-Pang; Pestell Richard G
Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.
The Journal of biological chemistry 2005;280(17):16934-41.
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2005: Xiao Guang-Hui; Gallagher Ryan; Shetler Justin; Skele Kristine; Altomare Deborah A; Pestell Richard G; Jhanwar Suresh; Testa Joseph R
The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.
Molecular and cellular biology 2005;25(6):2384-94.
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2005: Bu Xia; Avraham Hava Karsenty; Li Xiaoyu; Lim Bing; Jiang Shuxian; Fu Yigong; Pestell Richard G; Avraham Shalom
Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells.
Oncogene 2005;24(14):2398-409.
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2005: Fan Saijun; Gao Min; Meng Qinghui; Laterra John J; Symons Marc H; Coniglio Sal; Pestell Richard G; Goldberg Itzhak D; Rosen Eliot M
Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection.
Oncogene 2005;24(10):1749-66.
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2005: Bouras Toula; Fu Maofu; Sauve Anthony A; Wang Fang; Quong Andrew A; Perkins Neil D; Hay Ronald T; Gu Wei; Pestell Richard G
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.
The Journal of biological chemistry 2005;280(11):10264-76.
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2005: Moadel Renee M; Weldon Richard H; Katz Ellen B; Lu Ping; Mani Joseph; Stahl Mark; Blaufox M Donald; Pestell Richard G; Charron Maureen J; Dadachova Ekaterina
Positherapy: targeted nuclear therapy of breast cancer with 18F-2-deoxy-2-fluoro-D-glucose.
Cancer research 2005;65(3):698-702.
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2005: Lewis Joan S; Thomas T J; Pestell Richard G; Albanese Chris; Gallo Michael A; Thomas Thresia
Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells.
Journal of molecular endocrinology 2005;34(1):91-105.
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2005: Lewis Joan S; Vijayanathan Veena; Thomas T J; Pestell Richard G; Albanese Chris; Gallo Michael A; Thomas Thresia
Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: a mechanism involving the p38 MAP kinase and phosphorylation of ATF-2.
Oncology research 2005;15(3):113-28.
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2004: Hilakivi-Clarke L; Wang C; Kalil M; Riggins R; Pestell R G
Nutritional modulation of the cell cycle and breast cancer.
Endocrine-related cancer 2004;11(4):603-22.
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2004: Cui Yukun; Zhang Mao; Pestell Richard; Curran Edward M; Welshons Wade V; Fuqua Suzanne A W
Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity.
Cancer research 2004;64(24):9199-208.
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2004: Williams Terence M; Medina Freddy; Badano Ines; Hazan Rachel B; Hutchinson John; Muller William J; Chopra Neeru G; Scherer Philipp E; Pestell Richard G; Lisanti Michael P
Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion.
The Journal of biological chemistry 2004;279(49):51630-46.
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2004: Fu Maofu; Wang Chenguang; Li Zhiping; Sakamaki Toshiyuki; Pestell Richard G
Minireview: Cyclin D1: normal and abnormal functions.
Endocrinology 2004;145(12):5439-47.
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2004: Bouras Toula; Lisanti Michael P; Pestell Richard G
Caveolin-1 in breast cancer.
Cancer biology & therapy 2004;3(10):931-41.
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2004: Guha Udayan; Mecklenburg Lars; Cowin Pamela; Kan Lixin; O'Guin W Michael; D'Vizio Dolores; Pestell Richard G; Paus Ralf; Kessler John A
Bone morphogenetic protein signaling regulates postnatal hair follicle differentiation and cycling.
The American journal of pathology 2004;165(3):729-40.
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2004: Mukherjee Shankar; Huang Huan; Petkova Stefka B; Albanese Chris; Pestell Richard G; Braunstein Vicki L; Christ George J; Wittner Murray; Lisanti Michael P; Berman Joan W; Weiss Louis M; Tanowitz Herbert B
Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells.
Infection and immunity 2004;72(9):5274-82.
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2004: Hulit James; Wang Chenguang; Li Zhiping; Albanese Chris; Rao Mahadev; Di Vizio Dolores; Shah Salimuddin; Byers Stephen W; Mahmood Radma; Augenlicht Leonard H; Russell Robert; Pestell Richard G
Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice.
Molecular and cellular biology 2004;24(17):7598-611.
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2004: Fu Maofu; Wang Chenguang; Zhang Xueping; Pestell Richard G
Acetylation of nuclear receptors in cellular growth and apoptosis.
Biochemical pharmacology 2004;68(6):1199-208.
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2004: Fu Maofu; Rao Mahadev; Wu Kongming; Wang Chenguang; Zhang Xueping; Hessien Mohamed; Yeung Yee-Guide; Gioeli Daniel; Weber Michael J; Pestell Richard G
The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity.
The Journal of biological chemistry 2004;279(28):29436-49.
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2004: D'Amico Mark; Wu Kongming; Fu Maofu; Rao Mahadev; Albanese Chris; Russell Robert G; Lian Hanzhou; Bregman David; White Michael A; Pestell Richard G
The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements.
Cancer research 2004;64(12):4122-30.
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2004: Williams Terence M; Lee Hyangkyu; Cheung Michelle W-C; Cohen Alex W; Razani Babak; Iyengar Puneeth; Scherer Philipp E; Pestell Richard G; Lisanti Michael P
Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.
The Journal of biological chemistry 2004;279(23):24745-56.
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2004: Pradeep Anamika; Sharma Chandan; Sathyanarayana Pradeep; Albanese Chris; Fleming John V; Wang Timothy C; Wolfe M Michael; Baker Kenneth M; Pestell Richard G; Rana Basabi
Gastrin-mediated activation of cyclin D1 transcription involves beta-catenin and CREB pathways in gastric cancer cells.
Oncogene 2004;23(20):3689-99.
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2004: Sharma Chandan; Pradeep Anamika; Pestell Richard G; Rana Basabi
Peroxisome proliferator-activated receptor gamma activation modulates cyclin D1 transcription via beta-catenin-independent and cAMP-response element-binding protein-dependent pathways in mouse hepatocytes.
The Journal of biological chemistry 2004;279(17):16927-38.
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2004: Burbelo Peter; Wellstein Anton; Pestell Richard G
Altered Rho GTPase signaling pathways in breast cancer cells.
Breast cancer research and treatment 2004;84(1):43-8.
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2004: Bateman Nicholas W; Tan Dongfeng; Pestell Richard G; Black Jennifer D; Black Adrian R
Intestinal tumor progression is associated with altered function of KLF5.
The Journal of biological chemistry 2004;279(13):12093-101.
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2004: Matsuo Tomoko; Matsumura Takeshi; Sakai Masakazu; Senokuchi Takafumi; Yano Miyuki; Kiritoshi Shinsuke; Sonoda Kazuhiro; Kukidome Daisuke; Pestell Richard G; Brownlee Michael; Nishikawa Takeshi; Araki Eiichi
15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-kappaB.
Biochemical and biophysical research communications 2004;314(3):817-23.
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2004: Balasenthil Seetharaman; Sahin Aysegul A; Barnes Christopher J; Wang Rui-An; Pestell Richard G; Vadlamudi Ratna K; Kumar Rakesh
p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells.
The Journal of biological chemistry 2004;279(2):1422-8.
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2004: Fu Maofu; Wang Chenguang; Zhang Xueping; Pestell Richard G
Signal transduction inhibitors in cellular function.
Methods in molecular biology (Clifton, N.J.) 2004;284():15-36.
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2004: Wang Chenguang; Li Zhiping; Fu Maofu; Bouras Toula; Pestell Richard G
Signal transduction mediated by cyclin D1: from mitogens to cell proliferation: a molecular target with therapeutic potential.
Cancer treatment and research 2004;119():217-37.
-
2004: Wang Chenguang; Fu Maofu; Pestell Richard G
Histone acetylation/deacetylation as a regulator of cell cycle gene expression.
Methods in molecular biology (Clifton, N.J.) 2004;241():207-16.
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2003: Xiong Jingbo; Fan Saijun; Meng Qinghui; Schramm Laura; Wang Chenguang; Bouzahza Boumedienne; Zhou Jinnian; Zafonte Brian; Goldberg Itzhak D; Haddad Bassem R; Pestell Richard G; Rosen Eliot M
BRCA1 inhibition of telomerase activity in cultured cells.
Molecular and cellular biology 2003;23(23):8668-90.
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2003: Fu Maofu; Rao Mahadev; Wang Chenguang; Sakamaki Toshiyuki; Wang Jian; Di Vizio Dolores; Zhang Xueping; Albanese Chris; Balk Steven; Chang Chawnshang; Fan Saijun; Rosen Eliot; Palvimo Jorma J; Jänne Olli A; Muratoglu Selen; Avantaggiati Maria Laura; Pestell Richard G
Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth.
Molecular and cellular biology 2003;23(23):8563-75.
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2003: Wu Kongming; Yang Ying; Wang Chenguang; Davoli Maria A; D'Amico Mark; Li Anping; Cveklova Kveta; Kozmik Zbynek; Lisanti Michael P; Russell Robert G; Cvekl Ales; Pestell Richard G
DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.
The Journal of biological chemistry 2003;278(51):51673-84.
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2003: Shah Salimuddin; Hecht Andreas; Pestell Richard; Byers Stephen W
Trans-repression of beta-catenin activity by nuclear receptors.
The Journal of biological chemistry 2003;278(48):48137-45.
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2003: Cai Dongpo; Iyer Anita; Felekkis Kyriacos N; Near Richard I; Luo Zhijun; Chernoff Jonathan; Albanese Chris; Pestell Richard G; Lerner Adam
AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter.
Cancer research 2003;63(20):6802-8.
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2003: Rosen Eliot M; Fan Saijun; Pestell Richard G; Goldberg Itzhak D
BRCA1 in hormone-responsive cancers.
Trends in endocrinology and metabolism: TEM 2003;14(8):378-85.
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2003: Iyengar Puneeth; Combs Terry P; Shah Shalin J; Gouon-Evans Valérie; Pollard Jeffrey W; Albanese Chris; Flanagan Louise; Tenniswood Martin P; Guha Chandan; Lisanti Michael P; Pestell Richard G; Scherer Philipp E
Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization.
Oncogene 2003;22(41):6408-23.
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2003: Rowlands Tracey M; Pechenkina Irina V; Hatsell Sarah J; Pestell Richard G; Cowin Pamela
Dissecting the roles of beta-catenin and cyclin D1 during mammary development and neoplasia.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11400-5.
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2003: Wang Chenguang; Pattabiraman Nagarajan; Zhou Jian Nian; Fu Maofu; Sakamaki Toshiyuki; Albanese Chris; Li Zhiping; Wu Kongming; Hulit James; Neumeister Peter; Novikoff Phyllis M; Brownlee Michael; Scherer Philipp E; Jones Joan G; Whitney Kathleen D; Donehower Lawrence A; Harris Emily L; Rohan Thomas; Johns David C; Pestell Richard G
Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.
Molecular and cellular biology 2003;23(17):6159-73.
-
2003: Rosen Eliot M; Fan Saijun; Pestell Richard G; Goldberg Itzhak D
BRCA1 gene in breast cancer.
Journal of cellular physiology 2003;196(1):19-41.
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2003: Nelsen Christopher J; Rickheim David G; Tucker Melissa M; McKenzie Travis J; Hansen Linda K; Pestell Richard G; Albrecht Jeffrey H
Amino acids regulate hepatocyte proliferation through modulation of cyclin D1 expression.
The Journal of biological chemistry 2003;278(28):25853-8.
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2003: Song Diane H; Rana Basabi; Wolfe Jessica R; Crimmins Geoffrey; Choi Caroline; Albanese Chris; Wang Timothy C; Pestell Richard G; Wolfe M Michael
Gastrin-induced gastric adenocarcinoma growth is mediated through cyclin D1.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(1):G217-22.
-
2003: Fu Maofu; Wang Chenguang; Zhang Xueping; Pestell Richard
Nuclear receptor modifications and endocrine cell proliferation.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):133-8.
-
2003: D'Amico Mark; Wu Kongming; Di Vizio Dolores; Reutens Anne T; Stahl Mark; Fu Maofu; Albanese Chris; Russell Robert G; Muller William J; White Michael; Negassa Abdissa; Lee Han-Woong; DePinho Ronald A; Pestell Richard G
The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
Cancer research 2003;63(12):3395-402.
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2003: Huang Erich; Ishida Seiichi; Pittman Jennifer; Dressman Holly; Bild Andrea; Kloos Mark; D'Amico Mark; Pestell Richard G; West Mike; Nevins Joseph R
Gene expression phenotypic models that predict the activity of oncogenic pathways.
Nature genetics 2003;34(2):226-30.
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2003: Neumeister Peter; Pixley Fiona J; Xiong Ying; Xie Huafeng; Wu Kongming; Ashton Anthony; Cammer Michael; Chan Amanda; Symons Marc; Stanley E Richard; Pestell Richard G
Cyclin D1 governs adhesion and motility of macrophages.
Molecular biology of the cell 2003;14(5):2005-15.
-
2003: Hu Yu-Long; Albanese Chris; Pestell Richard G; Jaffe Robert B
Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells.
Journal of the National Cancer Institute 2003;95(10):733-40.
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2003: Huang Huan; Petkova Stefka B; Cohen Alex W; Bouzahzah Boumediene; Chan John; Zhou Jian-nian; Factor Stephen M; Weiss Louis M; Krishnamachary Mohan; Mukherjee Shankar; Wittner Murray; Kitsis Richard N; Pestell Richard G; Lisanti Michael P; Albanese Chris; Tanowitz Herbert B
Activation of transcription factors AP-1 and NF-kappa B in murine Chagasic myocarditis.
Infection and immunity 2003;71(5):2859-67.
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2003: Williams Terence M; Cheung Michelle W-C; Park David S; Razani Babak; Cohen Alex W; Muller William J; Di Vizio Dolores; Chopra Neeru G; Pestell Richard G; Lisanti Michael P
Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice.
Molecular biology of the cell 2003;14(3):1027-42.
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2003: Albanese Chris; Wu Kongming; D'Amico Mark; Jarrett Christy; Joyce David; Hughes Julian; Hulit James; Sakamaki Toshiyuki; Fu Maofu; Ben-Ze'ev Avri; Bromberg Jacqueline F; Lamberti Carmela; Verma Udit; Gaynor Richard B; Byers Stephen W; Pestell Richard G
IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.
Molecular biology of the cell 2003;14(2):585-99.
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2003: Xian Ma Yong; Fan Saijun; Xiong Jingbo; Yuan Ren-Qi; Meng Qinghui; Gao Min; Goldberg Itzhak D; Fuqua Suzanne A; Pestell Richard G; Rosen Eliot M
Role of BRCA1 in heat shock response.
Oncogene 2003;22(1):10-27.
-
2002: Lin Weiying; Albanese Chris; Pestell Richard G; Lawrence David S
Spatially discrete, light-driven protein expression.
Chemistry & biology 2002;9(12):1347-53.
-
2002: Lin Huei-Min; Pestell Richard G; Raz Avraham; Kim Hyeong-Reh Choi
Galectin-3 enhances cyclin D(1) promoter activity through SP1 and a cAMP-responsive element in human breast epithelial cells.
Oncogene 2002;21(52):8001-10.
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2002: Holnthoner Wolfgang; Pillinger Manuela; Groger Marion; Wolff Klaus; Ashton Anthony W; Albanese Chris; Neumeister Peter; Pestell Richard G; Petzelbauer Peter
Fibroblast growth factor-2 induces Lef/Tcf-dependent transcription in human endothelial cells.
The Journal of biological chemistry 2002;277(48):45847-53.
-
2002: Neumeister Peter; Albanese Chris; Balent Beate; Greally John; Pestell Richard G
Senescence and epigenetic dysregulation in cancer.
The international journal of biochemistry & cell biology 2002;34(11):1475-90.
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2002: Park David S; Lee Hyangkyu; Frank Philippe G; Razani Babak; Nguyen Andrew V; Parlow Albert F; Russell Robert G; Hulit James; Pestell Richard G; Lisanti Michael P
Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.
Molecular biology of the cell 2002;13(10):3416-30.
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2002: Lee Hyangkyu; Park David S; Razani Babak; Russell Robert G; Pestell Richard G; Lisanti Michael P
Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia.
The American journal of pathology 2002;161(4):1357-69.
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2002: Guha Udayan; Gomes William A; Kobayashi Tatsuya; Pestell Richard G; Kessler John A
In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb.
Developmental biology 2002;249(1):108-20.
-
2002: Hulit James; Lee Richard J; Russell Robert G; Pestell Richard G
ErbB-2-induced mammary tumor growth: the role of cyclin D1 and p27Kip1.
Biochemical pharmacology 2002;64(5-6):827-36.
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2002: Huang Huan; Yanagisawa Masashi; Kisanuki Yaz Y; Jelicks Linda A; Chandra Madhulika; Factor Stephen M; Wittner Murray; Weiss Louis M; Pestell Richard G; Shtutin Vitaliy; Shirani Jamshid; Tanowitz Herbert B
Role of cardiac myocyte-derived endothelin-1 in chagasic cardiomyopathy: molecular genetic evidence.
Clinical science (London, England : 1979) 2002;103 Suppl 48():263S-266S.
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2002: Page Kristen; Li Jing; Corbit Kevin C; Rumilla Kandelaria M; Soh Jae-Won; Weinstein I Bernard; Albanese Chris; Pestell Richard G; Rosner Marsha R; Hershenson Marc B
Regulation of airway smooth muscle cyclin D1 transcription by protein kinase C-delta.
American journal of respiratory cell and molecular biology 2002;27(2):204-13.
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2002: Zhang Zhi-Kai; Davies Kelvin P; Allen Jeffrey; Zhu Liang; Pestell Richard G; Zagzag David; Kalpana Ganjam V
Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.
Molecular and cellular biology 2002;22(16):5975-88.
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2002: Wu Kongming; Wang Chenguang; D'Amico Mark; Lee Richard J; Albanese Chris; Pestell Richard G; Mani Sridhar
Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways.
Molecular cancer therapeutics 2002;1(9):695-706.
-
2002: Suzui Masumi; Masuda Muneyuki; Lim Jin T E; Albanese Chris; Pestell Richard G; Weinstein I Bernard
Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1.
Cancer research 2002;62(14):3997-4006.
-
2002: Liu Meng-Min; Albanese Chris; Anderson Carol M; Hilty Kristin; Webb Paul; Uht Rosalie M; Price Richard H; Pestell Richard G; Kushner Peter J
Opposing action of estrogen receptors alpha and beta on cyclin D1 gene expression.
The Journal of biological chemistry 2002;277(27):24353-60.
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2002: Fu Maofu; Wang Chenguang; Wang Jian; Zafonte Brian T; Lisanti Michael P; Pestell Richard G
Acetylation in hormone signaling and the cell cycle.
Cytokine & growth factor reviews 2002;13(3):259-76.
-
2002: Kim Mee-Ohk; Si Qiusheng; Zhou Jian Nian; Pestell Richard G; Brosnan Celia F; Locker Joseph; Lee Sunhee C
Interferon-beta activates multiple signaling cascades in primary human microglia.
Journal of neurochemistry 2002;81(6):1361-71.
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2002: Shivakumar Latha; Minna John; Sakamaki Toshiyuki; Pestell Richard; White Michael A
The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.
Molecular and cellular biology 2002;22(12):4309-18.
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2002: Tanaka Hirokazu; Matsumura Itaru; Ezoe Sachiko; Satoh Yusuke; Sakamaki Toshiyuki; Albanese Chris; Machii Takashi; Pestell Richard G; Kanakura Yuzuru
E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination.
Molecular cell 2002;9(5):1017-29.
-
2002: Fu Maofu; Wang Chenguang; Wang Jian; Zhang Xueping; Sakamaki Toshiyuki; Yeung Y G; Chang Chawnshang; Hopp Torsten; Fuqua Suzanne A W; Jaffray Ellis; Hay Ron T; Palvimo Jorma J; Jänne Olli A; Pestell Richard G
Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function.
Molecular and cellular biology 2002;22(10):3373-88.
-
2002: Hanai Jun-ichi; Dhanabal Mohan; Karumanchi S Ananth; Albanese Chris; Waterman Matthew; Chan Barden; Ramchandran Ramani; Pestell Richard; Sukhatme Vikas P
Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1.
The Journal of biological chemistry 2002;277(19):16464-9.
-
2002: Albanese Chris; Hulit James; Sakamaki Toshiyuki; Pestell Richard G
Recent advances in inducible expression in transgenic mice.
Seminars in cell & developmental biology 2002;13(2):129-41.
-
2002: Bearss David J; Lee Richard J; Troyer Dean A; Pestell Richard G; Windle Jolene J
Differential effects of p21(WAF1/CIP1) deficiency on MMTV-ras and MMTV-myc mammary tumor properties.
Cancer research 2002;62(7):2077-84.
-
2002: Amanatullah D F; Zafonte B T; Pestell R G
The cell cycle in steroid hormone regulated proliferation and differentiation.
Minerva endocrinologica 2002;27(1):7-20.
-
2002: Fan Saijun; Ma Yong Xian; Wang Chenguang; Yuan Ren-Qi; Meng Qinghui; Wang Ji-An; Erdos Michael; Goldberg Itzhak D; Webb Paul; Kushner Peter J; Pestell Richard G; Rosen Eliot M
p300 Modulates the BRCA1 inhibition of estrogen receptor activity.
Cancer research 2002;62(1):141-51.
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2002: Hawcroft Gillian; D'Amico Mark; Albanese Chris; Markham Alexander F; Pestell Richard G; Hull Mark A
Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells.
Carcinogenesis 2002;23(1):107-14.
-
2001: Bouzahzah B; Albanese C; Ahmed F; Pixley F; Lisanti M P; Segall J D; Condeelis J; Joyce D; Minden A; Der C J; Chan A; Symons M; Pestell R G
Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways.
Molecular medicine (Cambridge, Mass.) 2001;7(12):816-30.
-
2001: Razani B; Engelman J A; Wang X B; Schubert W; Zhang X L; Marks C B; Macaluso F; Russell R G; Li M; Pestell R G; Di Vizio D; Hou H; Kneitz B; Lagaud G; Christ G J; Edelmann W; Lisanti M P
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.
The Journal of biological chemistry 2001;276(41):38121-38.
-
2001: Fan S; Yuan R; Ma Y X; Xiong J; Meng Q; Erdos M; Zhao J N; Goldberg I D; Pestell R G; Rosen E M
Disruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein binding.
Oncogene 2001;20(35):4827-41.
-
2001: Galbiati F; Volonté D; Liu J; Capozza F; Frank P G; Zhu L; Pestell R G; Lisanti M P
Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.
Molecular biology of the cell 2001;12(8):2229-44.
-
2001: Petkova S B; Huang H; Factor S M; Pestell R G; Bouzahzah B; Jelicks L A; Weiss L M; Douglas S A; Wittner M; Tanowitz H B
The role of endothelin in the pathogenesis of Chagas' disease.
International journal for parasitology 2001;31(5-6):499-511.
-
2001: Reutens A T; Fu M; Wang C; Albanese C; McPhaul M J; Sun Z; Balk S P; Jänne O A; Palvimo J J; Pestell R G
Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner.
Molecular endocrinology (Baltimore, Md.) 2001;15(5):797-811.
-
2001: Wang C; Fu M; Angeletti R H; Siconolfi-Baez L; Reutens A T; Albanese C; Lisanti M P; Katzenellenbogen B S; Kato S; Hopp T; Fuqua S A; Lopez G N; Kushner P J; Pestell R G
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity.
The Journal of biological chemistry 2001;276(21):18375-83.
-
2001: Condeelis J S; Wyckoff J B; Bailly M; Pestell R; Lawrence D; Backer J; Segall J E
Lamellipodia in invasion.
Seminars in cancer biology 2001;11(2):119-28.
-
2001: Wang C; Fu M; Mani S; Wadler S; Senderowicz A M; Pestell R G
Histone acetylation and the cell-cycle in cancer.
Frontiers in bioscience : a journal and virtual library 2001;6():D610-29.
-
2001: Joyce D; Albanese C; Steer J; Fu M; Bouzahzah B; Pestell R G
NF-kappaB and cell-cycle regulation: the cyclin connection.
Cytokine & growth factor reviews 2001;12(1):73-90.
-
2001: Volonté D; Galbiati F; Pestell R G; Lisanti M P
Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress.
The Journal of biological chemistry 2001;276(11):8094-103.
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2001: Fan S; Ma Y X; Wang C; Yuan R Q; Meng Q; Wang J A; Erdos M; Goldberg I D; Webb P; Kushner P J; Pestell R G; Rosen E M
Role of direct interaction in BRCA1 inhibition of estrogen receptor activity.
Oncogene 2001;20(1):77-87.
-
2001: Hulit J; Di Vizio D; Pestell R G
Inducible transgenics. New lessons on events governing the induction and commitment in mammary tumorigenesis.
Breast cancer research : BCR 2001;3(4):209-12.
-
2001: Zafonte B T; Amanatullah D F; Sage D; Augenlicht L H; Pestell R G
Ras regulation of cyclin-dependent immunoprecipitation kinase assays.
Methods in enzymology 2001;333():127-38.
-
2001: Amanatullah D F; Zafonte B T; Albanese C; Fu M; Messiers C; Hassell J; Pestell R G
Ras regulation of cyclin D1 promoter.
Methods in enzymology 2001;333():116-27.
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2000: Zafonte B T; Hulit J; Amanatullah D F; Albanese C; Wang C; Rosen E; Reutens A; Sparano J A; Lisanti M P; Pestell R G
Cell-cycle dysregulation in breast cancer: breast cancer therapies targeting the cell cycle.
Frontiers in bioscience : a journal and virtual library 2000;5():D938-61.
-
2000: Schlegel A; Pestell R G; Lisanti M P
Caveolins in cholesterol trafficking and signal transduction: implications for human disease.
Frontiers in bioscience : a journal and virtual library 2000;5():D929-37.
-
2000: Wang C; Francis R; Harirchian S; Batlle D; Mayhew B; Bassett M; Rainey W E; Pestell R G
The application of high density microarray for analysis of mitogenic signaling and cell-cycle in the adrenal.
Endocrine research 2000;26(4):807-23.
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2000: Huang H; Petkova S B; Pestell R G; Bouzahzah B; Chan J; Magazine H; Weiss L M; Christ G J; Lisanti M P; Douglas S A; Shtutin V; Halonen S K; Wittner M; Tanowitz H B
Trypanosoma cruzi infection (Chagas' disease) of mice causes activation of the mitogen-activated protein kinase cascade and expression of endothelin-1 in the myocardium.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S148-50.
-
2000: Razani B; Altschuler Y; Zhu L; Pestell R G; Mostov K E; Lisanti M P
Caveolin-1 expression is down-regulated in cells transformed by the human papilloma virus in a p53-dependent manner. Replacement of caveolin-1 expression suppresses HPV-mediated cell transformation.
Biochemistry 2000;39(45):13916-24.
-
2000: Lee H; Volonte D; Galbiati F; Iyengar P; Lublin D M; Bregman D B; Wilson M T; Campos-Gonzalez R; Bouzahzah B; Pestell R G; Scherer P E; Lisanti M P
Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette.
Molecular endocrinology (Baltimore, Md.) 2000;14(11):1750-75.
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2000: Bailly M; Wyckoff J; Bouzahzah B; Hammerman R; Sylvestre V; Cammer M; Pestell R; Segall J E
Epidermal growth factor receptor distribution during chemotactic responses.
Molecular biology of the cell 2000;11(11):3873-83.
-
2000: Henry D O; Moskalenko S A; Kaur K J; Fu M; Pestell R G; Camonis J H; White M A
Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB.
Molecular and cellular biology 2000;20(21):8084-92.
-
2000: Page K; Li J; Wang Y; Kartha S; Pestell R G; Hershenson M B
Regulation of cyclin D(1) expression and DNA synthesis by phosphatidylinositol 3-kinase in airway smooth muscle cells.
American journal of respiratory cell and molecular biology 2000;23(4):436-43.
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2000: Shie J L; Chen Z Y; O'Brien M J; Pestell R G; Lee M E; Tseng C C
Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(4):G806-14.
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2000: D'Amico M; Hulit J; Amanatullah D F; Zafonte B T; Albanese C; Bouzahzah B; Fu M; Augenlicht L H; Donehower L A; Takemaru K; Moon R T; Davis R; Lisanti M P; Shtutman M; Zhurinsky J; Ben-Ze'ev A; Troussard A A; Dedhar S; Pestell R G
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.
The Journal of biological chemistry 2000;275(42):32649-57.
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2000: Petkova S B; Tanowitz H B; Magazine H I; Factor S M; Chan J; Pestell R G; Bouzahzah B; Douglas S A; Shtutin V; Morris S A; Tsang E; Weiss L M; Christ G J; Wittner M; Huang H
Myocardial expression of endothelin-1 in murine Trypanosoma cruzi infection.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2000;9(5):257-65.
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2000: Bouzahzah B; Fu M; Iavarone A; Factor V M; Thorgeirsson S S; Pestell R G
Transforming growth factor-beta1 recruits histone deacetylase 1 to a p130 repressor complex in transgenic mice in vivo.
Cancer research 2000;60(16):4531-7.
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2000: Shie J L; Chen Z Y; Fu M; Pestell R G; Tseng C C
Gut-enriched Krüppel-like factor represses cyclin D1 promoter activity through Sp1 motif.
Nucleic acids research 2000;28(15):2969-76.
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2000: Galbiati F; Volonte D; Brown A M; Weinstein D E; Ben-Ze'ev A; Pestell R G; Lisanti M P
Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains.
The Journal of biological chemistry 2000;275(30):23368-77.
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2000: Fu M; Wang C; Reutens A T; Wang J; Angeletti R H; Siconolfi-Baez L; Ogryzko V; Avantaggiati M L; Pestell R G
p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation.
The Journal of biological chemistry 2000;275(27):20853-60.
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2000: Zhang W; Razani B; Altschuler Y; Bouzahzah B; Mostov K E; Pestell R G; Lisanti M P
Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1.
The Journal of biological chemistry 2000;275(27):20717-25.
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2000: Hulit J; Bash T; Fu M; Galbiati F; Albanese C; Sage D R; Schlegel A; Zhurinsky J; Shtutman M; Ben-Ze'ev A; Lisanti M P; Pestell R G
The cyclin D1 gene is transcriptionally repressed by caveolin-1.
The Journal of biological chemistry 2000;275(28):21203-9.
-
2000: Zahler M H; Irani A; Malhi H; Reutens A T; Albanese C; Bouzahzah B; Joyce D; Gupta S; Pestell R G
The application of a lentiviral vector for gene transfer in fetal human hepatocytes.
The journal of gene medicine 2000;2(3):186-93.
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2000: Albanese C; Reutens A T; Bouzahzah B; Fu M; D'Amico M; Link T; Nicholson R; Depinho R A; Pestell R G
Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(7):877-84.
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2000: Petkova S B; Ashton A; Bouzahzah B; Huang H; Pestell R G; Tanowitz H B
Cell cycle molecules and diseases of the cardiovascular system.
Frontiers in bioscience : a journal and virtual library 2000;5():D452-60.
-
2000: Amanatullah D F; Reutens A T; Zafonte B T; Fu M; Mani S; Pestell R G
Cell-cycle dysregulation and the molecular mechanisms of prostate cancer.
Frontiers in bioscience : a journal and virtual library 2000;5():D372-90.
-
2000: Lin S Y; Xia W; Wang J C; Kwong K Y; Spohn B; Wen Y; Pestell R G; Hung M C
Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4262-6.
-
2000: Shambaugh G E; Haines G K; Koch A; Lee E J; Zhou J n; Pestell R
Immunohistochemical examination of the INK4 and Cip inhibitors in the rat neonatal cerebellum: cellular localization and the impact of protein calorie malnutrition.
Brain research 2000;855(1):11-22.
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1999: Albanese C; D'Amico M; Reutens A T; Fu M; Watanabe G; Lee R J; Kitsis R N; Henglein B; Avantaggiati M; Somasundaram K; Thimmapaya B; Pestell R G
Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis.
The Journal of biological chemistry 1999;274(48):34186-95.
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1999: Schlegel A; Wang C; Katzenellenbogen B S; Pestell R G; Lisanti M P
Caveolin-1 potentiates estrogen receptor alpha (ERalpha) signaling. caveolin-1 drives ligand-independent nuclear translocation and activation of ERalpha.
The Journal of biological chemistry 1999;274(47):33551-6.
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1999: Engelman J A; Zhang X L; Razani B; Pestell R G; Lisanti M P
p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity.
The Journal of biological chemistry 1999;274(45):32333-41.
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1999: Joyce D; Bouzahzah B; Fu M; Albanese C; D'Amico M; Steer J; Klein J U; Lee R J; Segall J E; Westwick J K; Der C J; Pestell R G
Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway.
The Journal of biological chemistry 1999;274(36):25245-9.
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1999: Bromberg J F; Wrzeszczynska M H; Devgan G; Zhao Y; Pestell R G; Albanese C; Darnell J E
Stat3 as an oncogene.
Cell 1999;98(3):295-303.
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1999: Pestell R G; Albanese C; Reutens A T; Segall J E; Lee R J; Arnold A
The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation.
Endocrine reviews 1999;20(4):501-34.
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1999: Pena P; Reutens A T; Albanese C; D'Amico M; Watanabe G; Donner A; Shu I W; Williams T; Pestell R G
Activator protein-2 mediates transcriptional activation of the CYP11A1 gene by interaction with Sp1 rather than binding to DNA.
Molecular endocrinology (Baltimore, Md.) 1999;13(8):1402-16.
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1999: Page K; Li J; Hodge J A; Liu P T; Vanden Hoek T L; Becker L B; Pestell R G; Rosner M R; Hershenson M B
Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells.
The Journal of biological chemistry 1999;274(31):22065-71.
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1999: Fan S; Wang J; Yuan R; Ma Y; Meng Q; Erdos M R; Pestell R G; Yuan F; Auborn K J; Goldberg I D; Rosen E M
BRCA1 inhibition of estrogen receptor signaling in transfected cells.
Science (New York, N.Y.) 1999;284(5418):1354-6.
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1999: Shtutman M; Zhurinsky J; Simcha I; Albanese C; D'Amico M; Pestell R; Ben-Ze'ev A
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5522-7.
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1999: Matsumura I; Kitamura T; Wakao H; Tanaka H; Hashimoto K; Albanese C; Downward J; Pestell R G; Kanakura Y
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells.
The EMBO journal 1999;18(5):1367-77.
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1999: Musa N L; Ramakrishnan M; Li J; Kartha S; Liu P; Pestell R G; Hershenson M B
Forskolin inhibits cyclin D1 expression in cultured airway smooth-muscle cells.
American journal of respiratory cell and molecular biology 1999;20(2):352-8.
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1998: Engelman J A; Zhang X; Galbiati F; Volonte D; Sotgia F; Pestell R G; Minetti C; Scherer P E; Okamoto T; Lisanti M P
Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy.
American journal of human genetics 1998;63(6):1578-87.
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1998: Galbiati F; Volonte D; Engelman J A; Watanabe G; Burk R; Pestell R G; Lisanti M P
Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade.
The EMBO journal 1998;17(22):6633-48.
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1998: Engelman J A; Lee R J; Karnezis A; Bearss D J; Webster M; Siegel P; Muller W J; Windle J J; Pestell R G; Lisanti M P
Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer.
The Journal of biological chemistry 1998;273(32):20448-55.
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1998: Watanabe G; Pena P; Shambaugh G E; Haines G K; Pestell R G
Regulation of cyclin dependent kinase inhibitor proteins during neonatal cerebella development.
Brain research. Developmental brain research 1998;108(1-2):77-87.
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1998: Ramakrishnan M; Musa N L; Li J; Liu P T; Pestell R G; Hershenson M B
Catalytic activation of extracellular signal-regulated kinases induces cyclin D1 expression in primary tracheal myocytes.
American journal of respiratory cell and molecular biology 1998;18(6):736-40.
-
1998: Watanabe G; Albanese C; Lee R J; Reutens A; Vairo G; Henglein B; Pestell R G
Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1.
Molecular and cellular biology 1998;18(6):3212-22.
-
1997: Xiong W; Pestell R; Rosner M R
Role of cyclins in neuronal differentiation of immortalized hippocampal cells.
Molecular and cellular biology 1997;17(11):6585-97.
-
1997: Watanabe G; Pena P; Albanese C; Wilsbacher L D; Young J B; Pestell R G
Adrenocorticotropin induction of stress-activated protein kinase in the adrenal cortex in vivo.
The Journal of biological chemistry 1997;272(32):20063-9.
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1996: Watanabe G; Howe A; Lee R J; Albanese C; Shu I W; Karnezis A N; Zon L; Kyriakis J; Rundell K; Pestell R G
Induction of cyclin D1 by simian virus 40 small tumor antigen.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):12861-6.
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1996: Pestell R G; Albanese C; Watanabe G; Lee R J; Lastowiecki P; Zon L; Ostrowski M; Jameson J L
Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways.
Molecular endocrinology (Baltimore, Md.) 1996;10(9):1084-94.
-
1995: Albanese C; Johnson J; Watanabe G; Eklund N; Vu D; Arnold A; Pestell R G
Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions.
The Journal of biological chemistry 1995;270(40):23589-97.
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1995: Pestell R G; Albanese C; Watanabe G; Johnson J; Eklund N; Lastowiecki P; Jameson J L
Epidermal growth factor and c-Jun act via a common DNA regulatory element to stimulate transcription of the ovine P-450 cholesterol side chain cleavage (CYP11A1) promoter.
The Journal of biological chemistry 1995;270(31):18301-8.
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1994: Pestell R G; Hollenberg A N; Albanese C; Jameson J L
c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs.
The Journal of biological chemistry 1994;269(49):31090-6.
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1994: Hollenberg A N; Pestell R G; Albanese C; Boers M E; Jameson J L
Multiple promoter elements in the human chorionic gonadotropin beta subunit genes distinguish their expression from the luteinizing hormone beta gene.
Molecular and cellular endocrinology 1994;106(1-2):111-9.
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