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John Peters

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Nicholas M Barnes; Tim G Hales; Sarah C R Lummis; John A Peters
The 5-HT3 receptor--the relationship between structure and function.
Matthew R Livesey; Michelle A Cooper; Tarek Z Deeb; Jane E Carland; Janna Kozuska; Tim G Hales; Jeremy J Lambert; John A Peters
Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor.
Tarek Z Deeb; Jane E Carland; Michelle A Cooper; Matthew R Livesey; Jeremy J Lambert; John A Peters; Tim G Hales
Dynamic modification of a mutant cytoplasmic cysteine residue modulates the conductance of the human 5-HT3A receptor.

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All Publications

2009: Nicholas M Barnes; Tim G Hales; Sarah C R Lummis; John A Peters
The 5-HT3 receptor--the relationship between structure and function.
Neuropharmacology 2009;56(1):273-84.
2008: Matthew R Livesey; Michelle A Cooper; Tarek Z Deeb; Jane E Carland; Janna Kozuska; Tim G Hales; Jeremy J Lambert; John A Peters
Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor.
The Journal of biological chemistry 2008;283(28):19301-13.
2007: Tarek Z Deeb; Jane E Carland; Michelle A Cooper; Matthew R Livesey; Jeremy J Lambert; John A Peters; Tim G Hales
Dynamic modification of a mutant cytoplasmic cysteine residue modulates the conductance of the human 5-HT3A receptor.
The Journal of biological chemistry 2007;282(9):6172-82.
2006: John A Peters; Jane E Carland; M A Cooper; M R Livesey; Tarek Z Deeb; Tim G Hales; Jeremy J Lambert
Novel structural determinants of single-channel conductance in nicotinic acetylcholine and 5-hydroxytryptamine type-3 receptors.
Biochemical Society transactions 2006;34(Pt 5):882-6.
2006: Tim G Hales; James I Dunlop; Tarek Z Deeb; Jane E Carland; Stephen P Kelley; Jeremy J Lambert; John A Peters
Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors.
The Journal of biological chemistry 2006;281(12):8062-71.
2005: John A Peters; Tim G Hales; Jeremy J Lambert
Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family: insights from the 5-HT3 receptor.
Trends in pharmacological sciences 2005;26(11):587-94.
2004: Barbara A Spruce; Lorna A Campbell; Niall McTavish; Michelle A Cooper; M Virginia L Appleyard; Mary O'Neill; Jacqueline Howie; Jayne Samson; Stephen Watt; Karen Murray; Doris McLean; Nick R Leslie; Steve Safrany; Michelle J Ferguson; John A Peters; Alan R Prescott; Gary Box; Angela Hayes; Bernard P Nutley; Florence I Raynaud; C Peter Downes; Jeremy J Lambert; Alastair Thompson; Suzanne A Eccles
Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo.
Cancer research 2004;64(14):4875-86.
2004: John A Peters; Stephen P Kelley; James I Dunlop; Ewen F Kirkness; Tim G Hales; Jeremy J Lambert
The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance.
Biochemical Society transactions 2004;32(Pt3):547-52.
2003: Jeremy J Lambert; Delia Belelli; Dianne R Peden; Audrey W Vardy; John A Peters
Neurosteroid modulation of GABAA receptors.
Progress in neurobiology 2003;71(1):67-80.
2003: Stephen P Kelley; James I Dunlop; Ewen F Kirkness; Jeremy J Lambert; John A Peters
A cytoplasmic region determines single-channel conductance in 5-HT3 receptors.
Nature 2003;424(6946):321-4.
2003: Delia Belelli; Anna-Lisa Muntoni; Simon D Merrywest; Luc J Gentet; Anna Casula; Helen Callachan; Paola Madau; David K Gemmell; Niall M Hamilton; Jeremy J Lambert; Keith T Sillar; John A Peters
The in vitro and in vivo enantioselectivity of etomidate implicates the GABAA receptor in general anaesthesia.
Neuropharmacology 2003;45(1):57-71.
2002: Gary W Boyd; Pamela Low; James I Dunlop; Laura A Robertson; Audrey W Vardy; Jeremy J Lambert; John A Peters; Christopher N Connolly
Assembly and cell surface expression of homomeric and heteromeric 5-HT3 receptors: the role of oligomerization and chaperone proteins.
Molecular and cellular neurosciences 2002;21(1):38-50.
2001: Alison Anderson; Delia Belelli; D Jonathan Bennett; K I Buchanan; Anna Casula; Andrew Cooke; Helen Feilden; David K Gemmell; Niall M Hamilton; E J Hutchinson; Jeremy J Lambert; Maurice S Maidment; R McGuire; Petula McPhail; S Miller; Anna-Lisa Muntoni; John A Peters; F H Sansbury; Donald Stevenson; Hardy Sundaram
Alpha-amino acid phenolic ester derivatives: novel water-soluble general anesthetic agents which allosterically modulate GABA(A) receptors.
Journal of medicinal chemistry 2001;44(22):3582-91.
1999: Delia Belelli; Marco Pistis; John A Peters; Jeremy J Lambert
General anaesthetic action at transmitter-gated inhibitory amino acid receptors.
Trends in pharmacological sciences 1999;20(12):496-502.
1999: Delia Belelli; D Pau; G Cabras; John A Peters; Jeremy J Lambert
A single amino acid confers barbiturate sensitivity upon the GABA rho 1 receptor.
British journal of pharmacology 1999;127(3):601-4.
1999: AG Hope; Delia Belelli; I D Mair; Jeremy J Lambert; John A Peters
Molecular determinants of (+)-tubocurarine binding at recombinant 5-hydroxytryptamine3A receptor subunits.
Molecular pharmacology 1999;55(6):1037-43.
1999: Delia Belelli; Marco Pistis; John A Peters; Jeremy J Lambert
The interaction of general anaesthetics and neurosteroids with GABA(A) and glycine receptors.
Neurochemistry international 1999;34(5):447-52.
1999: Marco Pistis; Delia Belelli; KA McGurk; John A Peters; Jeremy J Lambert
Complementary regulation of anaesthetic activation of human (alpha6beta3gamma2L) and Drosophila (RDL) GABA receptors by a single amino acid residue.
The Journal of physiology 1999;515 ( Pt 1)():3-18.
1999: Paul Davies; Marco Pistis; MC Hanna; John A Peters; Jeremy J Lambert; Tim G Hales; Ewen F Kirkness
The 5-HT3B subunit is a major determinant of serotonin-receptor function.
Nature 1999;397(6717):359-63.
1998: I D Mair; Jeremy J Lambert; J Yang; John Dempster; John A Peters
Pharmacological characterization of a rat 5-hydroxytryptamine type3 receptor subunit (r5-HT3A(b)) expressed in Xenopus laevis oocytes.
British journal of pharmacology 1998;124(8):1667-74.
1998: A M Brown; AG Hope; Jeremy J Lambert; John A Peters
Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A).
The Journal of physiology 1998;507 ( Pt 3)():653-65.
1997: John A Peters; Jeremy J Lambert
Anaesthetics in a bind?
Trends in pharmacological sciences 1997;18(12):454-5.
1997: Marco Pistis; Delia Belelli; John A Peters; Jeremy J Lambert
The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study.
British journal of pharmacology 1997;122(8):1707-19.
1997: Delia Belelli; Jeremy J Lambert; John A Peters; Keith A Wafford; Paul J Whiting
The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):11031-6.
1997: Alison Anderson; A C Boyd; Alan Byford; A C Campbell; David K Gemmell; Niall M Hamilton; David R Hill; C Hill-Venning; Jeremy J Lambert; Maurice S Maidment; V May; R J Marshall; John A Peters; David C Rees; Donald Stevenson; Hardy Sundaram
Anesthetic activity of novel water-soluble 2 beta-morpholinyl steroids and their modulatory effects at GABAA receptors.
Journal of medicinal chemistry 1997;40(11):1668-81.
1996: A G Hope; John A Peters; A M Brown; Jeremy J Lambert; Thomas Blackburn
Characterization of a human 5-hydroxytryptamine3 receptor type A (h5-HT3R-AS) subunit stably expressed in HEK 293 cells.
British journal of pharmacology 1996;118(5):1237-45.
1996: Delia Belelli; H Callachan; C Hill-Venning; John A Peters; Jeremy J Lambert
Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes.
British journal of pharmacology 1996;118(3):563-76.
1996: Jeremy J Lambert; Delia Belelli; C Hill-Venning; H Callachan; John A Peters
Neurosteroid modulation of native and recombinant GABAA receptors.
Cellular and molecular neurobiology 1996;16(2):155-74.
1996: Delia Belelli; Jeremy J Lambert; John A Peters; Kelvin W Gee; NC Lan
Modulation of human recombinant GABAA receptors by pregnanediols.
Neuropharmacology 1996;35(9-10):1223-31.
1996: C Hill-Venning; John A Peters; H Callachan; Jeremy J Lambert; D K Gemmell; A Anderson; A Byford; N Hamilton; D R Hill; R J Marshall; A C Campbell
The anaesthetic action and modulation of GABAA receptor activity by the novel water-soluble aminosteroid Org 20599.
Neuropharmacology 1996;35(9-10):1209-22.
1995: Delia Belelli; J M Balcarek; A G Hope; John A Peters; Jeremy J Lambert; Thomas Blackburn
Cloning and functional expression of a human 5-hydroxytryptamine type 3AS receptor subunit.
Molecular pharmacology 1995;48(6):1054-62.
1995: L J Steward; J Ge; K R Bentley; PC Barber; A G Hope; Jeremy J Lambert; John A Peters; Thomas Blackburn; Nicholas M Barnes
Evidence that the atypical 5-HT3 receptor ligand, [3H]-BRL46470, labels additional 5-HT3 binding sites compared to [3H]-granisetron.
British journal of pharmacology 1995;116(2):1781-8.
1995: Jeremy J Lambert; Delia Belelli; C Hill-Venning; John A Peters
Neurosteroids and GABAA receptor function.
Trends in pharmacological sciences 1995;16(9):295-303.
1995: D L Downie; A G Hope; Delia Belelli; Jeremy J Lambert; John A Peters; K R Bentley; L J Steward; C Y Chen; Nicholas M Barnes
The interaction of trichloroethanol with murine recombinant 5-HT3 receptors.
British journal of pharmacology 1995;114(8):1641-51.
1995: C H Gill; John A Peters; Jeremy J Lambert
An electrophysiological investigation of the properties of a murine recombinant 5-HT3 receptor stably expressed in HEK 293 cells.
British journal of pharmacology 1995;114(6):1211-21.
1994: R Chen; Delia Belelli; Jeremy J Lambert; John A Peters; A Reyes; NC Lan
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):6069-73.
1994: D L Downie; A G Hope; Jeremy J Lambert; John A Peters; Thomas Blackburn; B J Jones
Pharmacological characterization of the apparent splice variants of the murine 5-HT3 R-A subunit expressed in Xenopus laevis oocytes.
Neuropharmacology 1994;33(3-4):473-82.
1993: John A Peters; H M Malone; Jeremy J Lambert
An electrophysiological investigation of the properties of 5-HT3 receptors of rabbit nodose ganglion neurones in culture.
British journal of pharmacology 1993;110(2):665-76.
1993: A G Hope; D L Downie; L Sutherland; Jeremy J Lambert; John A Peters; Brian Burchell
Cloning and functional expression of an apparent splice variant of the murine 5-HT3 receptor A subunit.
European journal of pharmacology 1993;245(2):187-92.
1992: John A Peters; H M Malone; Jeremy J Lambert
Recent advances in the electrophysiological characterization of 5-HT3 receptors.
Trends in pharmacological sciences 1992;13(10):391-7.
1992: J M Nooney; John A Peters; Jeremy J Lambert
A patch clamp study of the nicotinic acetylcholine receptor of bovine adrenomedullary chromaffin cells in culture.
The Journal of physiology 1992;455():503-27.
1992: C Hill-Venning; Jeremy J Lambert; John A Peters; Tim G Hales; C Gill; H Callachan; N C Sturgess
The actions of endogenous and synthetic pregnane steroids on GABAA receptors.
Advances in biochemical psychopharmacology 1992;47():93-102.
1992: C Hill-Venning; John A Peters; Jeremy J Lambert
The interaction of steroids with inhibitory and excitatory amino acid receptors.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():683A-684A.
1991: John A Peters; H M Malone; Jeremy J Lambert
Ketamine potentiates 5-HT3 receptor-mediated currents in rabbit nodose ganglion neurones.
British journal of pharmacology 1991;103(3):1623-5.
1991: H M Malone; John A Peters; Jeremy J Lambert
Physiological and pharmacological properties of 5-HT3 receptors--a patch clamp-study.
Neuropeptides 1991;19 Suppl():25-30.
1990: John A Peters; H M Malone; Jeremy J Lambert
Antagonism of 5-HT3 receptor mediated currents in murine N1E-115 neuroblastoma cells by (+)-tubocurarine.
Neuroscience letters 1990;110(1-2):107-12.
1990: Jeremy J Lambert; John A Peters; N C Sturgess; Tim G Hales
Steroid modulation of the GABAA receptor complex: electrophysiological studies.
Ciba Foundation symposium 1990;153():56-71; discussion 71-82.
1989: John A Peters; Jeremy J Lambert; G A Cottrell
An electrophysiological investigation of the characteristics and function of GABAA receptors on bovine adrenomedullary chromaffin cells.
Pflügers Archiv : European journal of physiology 1989;415(1):95-103.
1989: Jeremy J Lambert; John A Peters; Tim G Hales; John Dempster
The properties of 5-HT3 receptors in clonal cell lines studied by patch-clamp techniques.
British journal of pharmacology 1989;97(1):27-40.
1989: R F Halliwell; John A Peters; Jeremy J Lambert
The mechanism of action and pharmacological specificity of the anticonvulsant NMDA antagonist MK-801: a voltage clamp study on neuronal cells in culture.
British journal of pharmacology 1989;96(2):480-94.
1988: John A Peters; Ewen F Kirkness; H Callachan; Jeremy J Lambert; A J Turner
Modulation of the GABAA receptor by depressant barbiturates and pregnane steroids.
British journal of pharmacology 1988;94(4):1257-69.
1988: John A Peters; Tim G Hales; Jeremy J Lambert
Divalent cations modulate 5-HT3 receptor-induced currents in N1E-115 neuroblastoma cells.
European journal of pharmacology 1988;151(3):491-5.
1987: H Callachan; G A Cottrell; N Y Hather; Jeremy J Lambert; J M Nooney; John A Peters
Modulation of the GABAA receptor by progesterone metabolites.
Proceedings of the Royal Society of London. Series B, Containing papers of a Biological character. Royal Society (Great Britain) 1987;231(1264):359-69.