FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Eric Bernhard

Research Profile

Physiology

Chemicals & Drugs

Genes & Molecular Sequences

Genes, ras

Living Beings

Anatomy

Disorders

Neoplasms

Co-author Network

Publications

TOP 3
In Ah Kim; Mina No; Jang-Mi Lee; Jin Hee Shin; Jee Sun Oh; Eun Jung Choi; Il Han Kim; Peter Atadja; Eric J Bernhard
Epigenetic modulation of radiation response in human cancer cells with activated EGFR or HER-2 signaling: potential role of histone deacetylase 6.
Nils Cordes; S Frick; T B Brunner; Christian Pilarsky; Robert Grützmann; Bence Sipos; Günter Klöppel; W Gillies McKenna; Eric J Bernhard
Human pancreatic tumor cells are sensitized to ionizing radiation by knockdown of caveolin-1.
Zibin Jiang; N Pore; george cerniglia; Rosemarie Mick; Maria-Magdelena Georgescu; Eric J Bernhard; Stephen M Hahn; Anjali K Gupta; Amit Maity
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Eric Bernhard (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2009: In Ah Kim; Mina No; Jang-Mi Lee; Jin Hee Shin; Jee Sun Oh; Eun Jung Choi; Il Han Kim; Peter Atadja; Eric J Bernhard
Epigenetic modulation of radiation response in human cancer cells with activated EGFR or HER-2 signaling: potential role of histone deacetylase 6.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;92(1):125-32.
2007: Nils Cordes; S Frick; T B Brunner; Christian Pilarsky; Robert Grützmann; Bence Sipos; Günter Klöppel; W Gillies McKenna; Eric J Bernhard
Human pancreatic tumor cells are sensitized to ionizing radiation by knockdown of caveolin-1.
Oncogene 2007;26(48):6851-62.
2007: Zibin Jiang; N Pore; george cerniglia; Rosemarie Mick; Maria-Magdelena Georgescu; Eric J Bernhard; Stephen M Hahn; Anjali K Gupta; Amit Maity
Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
Cancer research 2007;67(9):4467-73.
2007: Keith A. Cengel; K Ranh Voong; Sanjay Chandrasekaran; Laurence Maggiorella; Thomas B Brunner; Eric Stanbridge; Gary D Kao; W Gillies McKenna; Eric J Bernhard
Oncogenic K-Ras signals through epidermal growth factor receptor and wild-type H-Ras to promote radiation survival in pancreatic and colorectal carcinoma cells.
Neoplasia (New York, N.Y.) 2007;9(4):341-8.
2006: N Pore; Anjali K Gupta; george cerniglia; Zibin Jiang; Eric J Bernhard; Sydney Evans; Cameron J Koch; Stephen M Hahn; Amit Maity
Nelfinavir down-regulates hypoxia-inducible factor 1alpha and VEGF expression and increases tumor oxygenation: implications for radiotherapy.
Cancer research 2006;66(18):9252-9.
2006: Keith A. Cengel; Eric Deutsch; Trevor C Stephens; K Ranh Voong; Gary D Kao; Eric J Bernhard
Radiosensitizing effects of the prenyltransferase inhibitor AZD3409 against RAS mutated cell lines.
Cancer biology & therapy 2006;5(9):1206-10.
2006: N Pore; Zibin Jiang; Hui-Kuo G Shu; Eric J Bernhard; Gary D Kao; Amit Maity
Akt1 activation can augment hypoxia-inducible factor-1alpha expression by increasing protein translation through a mammalian target of rapamycin-independent pathway.
Molecular cancer research : MCR 2006;4(7):471-9.
2005: Thomas B Brunner; Keith A. Cengel; Stephen M Hahn; Junmin Wu; Douglas L Fraker; W Gillies McKenna; Eric J Bernhard
Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras.
Cancer research 2005;65(18):8433-41.
2005: In Ah Kim; Sun Sik Bae; Annemarie Fernandes; Junmin Wu; Ruth J Muschel; W Gillies McKenna; Morris J Birnbaum; Eric J Bernhard
Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines.
Cancer research 2005;65(17):7902-10.
2005: Yuquan Shi; Caroline S Lee; Junmin Wu; Cameron J Koch; Stephen R Thom; Amit Maity; Eric J Bernhard
Effects of hyperbaric oxygen exposure on experimental head and neck tumor growth, oxygenation, and vasculature.
Head & neck 2005;27(5):362-9.
2005: Niklas Finnberg; Joshua J Gruber; Peiwen Fei; Dorothea Rudolph; Anka Bric; Seok-Hyun Kim; Timothy F Burns; Hope Ajuha; Robert Page; Gen Sheng Wu; Youhai Chen; W Gillies McKenna; Eric J Bernhard; Scott W Lowe; Tak Mak; Wafik S El-Deiry
DR5 knockout mice are compromised in radiation-induced apoptosis.
Molecular and cellular biology 2005;25(5):2000-13.
2005: Yuquan Shi; Junmin Wu; Rosemarie Mick; george cerniglia; Elizabeth Cohen-Jonathan; Johng S Rhim; Cameron J Koch; Eric J Bernhard
Farnesyltransferase inhibitor effects on prostate tumor micro-environment and radiation survival.
The Prostate 2005;62(1):69-82.
2004: Shih-Wen Lin; Michelle Cook; Niklas Finnberg; Eric J Bernhard; Don Baldwin; Wafik S El-Deiry
p53-dependent induction of serine proteases in irradiated mouse colon.
Cancer biology & therapy 2004;3(12):1290-7.
2004: Peiwen Fei; Wenge Wang; Seok-hyun Kim; Shulin Wang; Timothy F Burns; Joanna K Sax; Monica Buzzai; David T Dicker; W Gillies McKenna; Eric J Bernhard; Wafik S El-Deiry
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth.
Cancer cell 2004;6(6):597-609.
2004: Eric J Bernhard
Farnesyltransferase inhibition: who are the Aktors?
Cancer biology & therapy 2004;3(11):1099-101.
2004: Thomas B Brunner; Stephen M Hahn; W Gillies McKenna; Eric J Bernhard
Radiation sensitization by inhibition of activated Ras.
Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al] 2004;180(11):731-40.
2004: N Pore; Shuang Liu; Hui-Kuo G Shu; Bin Li; Daphne A Haas-Kogan; David Stokoe; Julie Milanini-Mongiat; Gilles Pages; Donald M O'Rourke; Eric J Bernhard; Amit Maity
Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1-independent mechanism.
Molecular biology of the cell 2004;15(11):4841-53.
2004: Neil E Martin; Thomas B Brunner; Krystyna Kiel; Thomas F DeLaney; William F Regine; Mohammed Mohiuddin; Ernest F Rosato; Daniel G Haller; James P Stevenson; Debbie Smith; Barnali Pramanik; Joel E Tepper; Wesley K Tanaka; Briggs Morrison; Paul Deutsch; Anjali K Gupta; Ruth J Muschel; W Gillies McKenna; Eric J Bernhard; Stephen M Hahn
A phase I trial of the dual farnesyltransferase and geranylgeranyltransferase inhibitor L-778,123 and radiotherapy for locally advanced pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(16):5447-54.
2004: In Ah Kim; Annemarie T Fernandes; Anjali K Gupta; W Gillies McKenna; Eric J Bernhard
The influence of Ras pathway signaling on tumor radiosensitivity.
Cancer metastasis reviews 2004;23(3-4):227-36.
2004: Franz S Schreiber; Therese B Deramaudt; Thomas B Brunner; Michael I Boretti; Keith J Gooch; Doris A Stoffers; Eric J Bernhard; Anil K Rustgi
Successful growth and characterization of mouse pancreatic ductal cells: functional properties of the Ki-RAS(G12V) oncogene.
Gastroenterology 2004;127(1):250-60.
2004: Bin Li; Min Yuan; In Ah Kim; Chi-Ming Chang; Eric J Bernhard; Hui-Kuo G Shu
Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin.
Oncogene 2004;23(26):4594-602.
2003: Thomas B Brunner; Stephen M Hahn; Anjali K Gupta; Ruth J Muschel; W Gillies McKenna; Eric J Bernhard
Farnesyltransferase inhibitors: an overview of the results of preclinical and clinical investigations.
Cancer research 2003;63(18):5656-68.
2003: W Gillies McKenna; Ruth J Muschel; Anjali K Gupta; Stephen M Hahn; Eric J Bernhard
The RAS signal transduction pathway and its role in radiation sensitivity.
Oncogene 2003;22(37):5866-75.
2003: Thomas B Brunner; Anjali K Gupta; Yuquan Shi; Stephen M Hahn; Ruth J Muschel; W Gillies McKenna; Eric J Bernhard
Farnesyltransferase inhibitors as radiation sensitizers.
International journal of radiation biology 2003;79(7):569-76.
2003: W Gillies McKenna; Ruth J Muschel; Anjali Gupta; Stephen Hahn; Eric J Bernhard
Signaling inhibition with radiation in colorectal cancer: clinical trials.
Seminars in oncology 2003;30(3 Suppl 6):56-67.
2003: Eric J Bernhard
RhoB and the cellular response to farnesyltransferase inhibitors: the search for clues to cell death mechanisms.
Cancer biology & therapy 2003;2(3):281-2.
2003: Anjali K Gupta; Eric J Bernhard; Vincent J Bakanauskas; george cerniglia; Ruth J Muschel; Gillies McKenna
C-Raf-1 protein kinase is not essential for Ras transformation of mouse embryo fibroblasts.
Cancer biology & therapy 2003;2(1):73-5.
2002: Peiwen Fei; Eric J Bernhard; Wafik S El-Deiry
Tissue-specific induction of p53 targets in vivo.
Cancer research 2002;62(24):7316-27.
2002: Joanna K Sax; Peiwen Fei; Maureen E Murphy; Eric J Bernhard; Stanley J Korsmeyer; Wafik S El-Deiry
BID regulation by p53 contributes to chemosensitivity.
Nature cell biology 2002;4(11):842-9.
2002: W Gillies McKenna; Ruth J Muschel; Anjali K Gupta; Stephen M Hahn; Eric J Bernhard
Farnesyltransferase inhibitors as radiation sensitizers.
Seminars in radiation oncology 2002;12(3 Suppl 2):27-32.
2002: Stephen M Hahn; Eric J Bernhard; William F Regine; Mohammed Mohiuddin; Daniel G Haller; James P Stevenson; Debbie Smith; Barnali Pramanik; Joel E Tepper; Thomas F DeLaney; Krystyna Kiel; Briggs Morrison; Paul Deutsch; Ruth J Muschel; W Gillies McKenna
A Phase I trial of the farnesyltransferase inhibitor L-778,123 and radiotherapy for locally advanced lung and head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(5):1065-72.
2002: Anjali K Gupta; W Gillies McKenna; Charles N Weber; Michael D Feldman; Jeffrey D Goldsmith; Rosemarie Mick; Mitchell Machtay; David I Rosenthal; Vincent J Bakanauskas; george cerniglia; Eric J Bernhard; Randal S Weber; Ruth J Muschel
Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(3):885-92.
2001: Stephen M Hahn; Eric J Bernhard; W Gillies McKenna
Farnesyltransferase inhibitors.
Seminars in oncology 2001;28(5 Suppl 16):86-93.
2001: Heather A Jones; Stephen M Hahn; Eric J Bernhard; W Gillies McKenna
Ras inhibitors and radiation therapy.
Seminars in radiation oncology 2001;11(4):328-37.
2001: Timothy F Burns; Eric J Bernhard; Wafik S El-Deiry
Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.
Oncogene 2001;20(34):4601-12.
2001: george cerniglia; Eric J Bernhard; George C Prendergast
RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6192-7.
2001: Anjali K Gupta; Vincent J Bakanauskas; george cerniglia; Y Cheng; Eric J Bernhard; Ruth J Muschel; W Gillies McKenna
The Ras radiation resistance pathway.
Cancer research 2001;61(10):4278-82.
2001: Elizabeth Cohen-Jonathan; Sydney Evans; Cameron J Koch; Ruth J Muschel; W Gillies McKenna; Junmin Wu; Eric J Bernhard
The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras.
Cancer research 2001;61(5):2289-93.
2001: Eric J Bernhard; Ruth J Muschel
Ras, metastasis, and matrix metalloproteinase 9.
Methods in enzymology 2001;333():96-104.
2001: Anjali K Gupta; Vincent J Bakanauskas; W Gillies McKenna; Eric J Bernhard; Ruth J Muschel
Ras regulation of radioresistance in cell culture.
Methods in enzymology 2001;333():284-90.
2001: Christopher W Wong; A Lee; L Shientag; Jiujiu Yu; Y Dong; Gary D Kao; Abu-Bakr Al-Mehdi; Eric J Bernhard; Ruth J Muschel
Apoptosis: an early event in metastatic inefficiency.
Cancer research 2001;61(1):333-8.
2000: Eric J Bernhard; E J Stanbridge; S Gupta; Anjali K Gupta; Daniel E Soto; Vincent J Bakanauskas; george cerniglia; Ruth J Muschel; W Gillies McKenna
Direct evidence for the contribution of activated N-ras and K-ras oncogenes to increased intrinsic radiation resistance in human tumor cell lines.
Cancer research 2000;60(23):6597-600.
2000: Elizabeth Cohen-Jonathan; Ruth J Muschel; W Gillies McKenna; Sydney Evans; george cerniglia; Rosemarie Mick; D Kusewitt; Said M Sebti; Andrew D Hamilton; Allen Oliff; Nancy E Kohl; Jackson B Gibbs; Eric J Bernhard
Farnesyltransferase inhibitors potentiate the antitumor effect of radiation on a human tumor xenograft expressing activated HRAS.
Radiation research 2000;154(2):125-32.
2000: Anjali K Gupta; Eric J Bernhard; Vincent J Bakanauskas; J Wu; Ruth J Muschel; W Gillies McKenna
RAS-Mediated radiation resistance is not linked to MAP kinase activation in two bladder carcinoma cell lines.
Radiation research 2000;154(1):64-72.
2000: Iraimoudi S Ayene; Eric J Bernhard; W Gillies McKenna; Ruth J Muschel; Robert E Krisch; Cameron J Koch
DNA as an important target in radiation-induced apoptosis of MYC and MYC plus RAS transfected rat embryo fibroblasts.
International journal of radiation biology 2000;76(3):343-54.
2000: Eric J Bernhard; James B Mitchell; Dennis F Deen; M Cardell; David I Rosenthal; J M Brown
Re-evaluating gadolinium(III) texaphyrin as a radiosensitizing agent.
Cancer research 2000;60(1):86-91.
1999: Eric J Bernhard; W Gillies McKenna; R J Muschel
Radiosensitivity and the cell cycle.
The cancer journal from Scientific American 1999;5(4):194-204.
1999: E C Jonathan; Eric J Bernhard; W Gillies McKenna
How does radiation kill cells?
Current opinion in chemical biology 1999;3(1):77-83.
1998: Ruth J Muschel; Daniel E Soto; W Gillies McKenna; Eric J Bernhard
Radiosensitization and apoptosis.
Oncogene 1998;17(25):3359-63.
1998: John E Biaglow; Cameron J Koch; Stephen W Tuttle; Yefim Manevich; Iraimoudi S Ayene; Eric J Bernhard; W Gillies McKenna; Alexander V Kachur
The measurement of bioreductive capacity of tumor cells using methylene blue.
International journal of radiation oncology, biology, physics 1998;42(4):769-73.
1998: Anna Janss; C Levow; Eric J Bernhard; Ruth J Muschel; W Gillies McKenna; L Sutton; Peter C Phillips
Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines.
Experimental cell research 1998;243(1):29-38.
1998: Eric J Bernhard; W Gillies McKenna; Andrew D Hamilton; Said M Sebti; Y Qian; J M Wu; Ruth J Muschel
Inhibiting Ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes.
Cancer research 1998;58(8):1754-61.
1997: Ruth J Muschel; W Gillies McKenna; Eric J Bernhard
Cell cycle checkpoints and apoptosis: potential for improving radiation therapy.
Vitamins and hormones 1997;53():1-25.
1996: Stephen W Tuttle; Ruth J Muschel; Eric J Bernhard; W Gillies McKenna; John E Biaglow
Decreased ability of cells overexpressing MYC proteins to reduce peroxide and hydroperoxides.
The British journal of cancer. Supplement 1996;27():S140-44.
1996: F Zhang; B Rathod; J B Jones; QM Wang; Eric J Bernhard; J J Godyn; George P Studzinski
Increased stringency of the 1,25-dihydroxyvitamin D3-induced G1 to S phase block in polyploid HL60 cells.
Journal of cellular physiology 1996;168(1):18-25.
1996: Eric J Bernhard; Ruth J Muschel; V J Bakanauskas; W Gillies McKenna
Reducing the radiation-induced G2 delay causes HeLa cells to undergo apoptosis instead of mitotic death.
International journal of radiation biology 1996;69(5):575-84.
1996: Eric J Bernhard; Gary D Kao; Adrienne D Cox; Said M Sebti; Andrew D Hamilton; Ruth J Muschel; W Gillies McKenna
The farnesyltransferase inhibitor FTI-277 radiosensitizes H-ras-transformed rat embryo fibroblasts.
Cancer research 1996;56(8):1727-30.
1996: W Gillies McKenna; Eric J Bernhard; D A Markiewicz; MS Rudoltz; Amit Maity; Ruth J Muschel
Regulation of radiation-induced apoptosis in oncogene-transfected fibroblasts: influence of H-ras on the G2 delay.
Oncogene 1996;12(2):237-45.
1995: Eric J Bernhard; Amit Maity; Ruth J Muschel; W Gillies McKenna
Effects of ionizing radiation on cell cycle progression. A review.
Radiation and environmental biophysics 1995;34(2):79-83.
1995: Eric J Bernhard; B Hagner; C Wong; I Lubenski; Ruth J Muschel
The effect of E1A transfection on MMP-9 expression and metastatic potential.
International journal of cancer. Journal international du cancer 1995;60(5):718-24.
1995: Ruth J Muschel; Eric J Bernhard; Luis Garza; W Gillies McKenna; Cameron J Koch
Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling.
Cancer research 1995;55(5):995-8.
1994: Eric J Bernhard; Amit Maity; Ruth J Muschel; W Gillies McKenna
Increased expression of cyclin B1 mRNA coincides with diminished G2-phase arrest in irradiated HeLa cells treated with staurosporine or caffeine.
Radiation research 1994;140(3):393-400.
1994: Eric J Bernhard; Stephen B Gruber; Ruth J Muschel
Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4293-7.
1994: Eric J Bernhard; W Gillies McKenna; Ruth J Muschel
Cyclin expression and G2-phase delay after irradiation.
Radiation research 1994;138(1 Suppl):S64-7.
1994: Bruce P Himelstein; R Canete-Soler; Eric J Bernhard; Ruth J Muschel
Induction of fibroblast 92 kDa gelatinase/type IV collagenase expression by direct contact with metastatic tumor cells.
Journal of cell science 1994;107 ( Pt 2)():477-86.
1994: Bruce P Himelstein; R Canete-Soler; Eric J Bernhard; D W Dilks; Ruth J Muschel
Metalloproteinases in tumor progression: the contribution of MMP-9.
Invasion & metastasis 1994;14(1-6):246-58.
1993: H Zhou; Eric J Bernhard; Floyd E Fox; Paul C Billings
Induction of metalloproteinase activity in human T-lymphocytes.
Biochimica et biophysica acta 1993;1177(2):174-8.
1991: W Gillies McKenna; G Iliakis; M C Weiss; Eric J Bernhard; Ruth J Muschel
Increased G2 delay in radiation-resistant cells obtained by transformation of primary rat embryo cells with the oncogenes H-ras and v-myc.
Radiation research 1991;125(3):283-7.
1990: Eric J Bernhard; Ruth J Muschel; E N Hughes
Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells.
Cancer research 1990;50(13):3872-7.