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John Pezzuto

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Endringer Denise C; Pezzuto John M; Braga Fernão C
NF-kappaB inhibitory activity of cyclitols isolated from Hancornia speciosa.
Pezzuto John M; Venkatasubramanian Venkat; Hamad Mazen; Morris Kenneth R
Unraveling the relationship between grapes and health.
Deng Ye; Balunas Marcy J; Kim Jeong-Ah; Lantvit Daniel D; Chin Young-Won; Chai Heebyung; Sugiarso Sugeng; Kardono Leonardus B S; Fong Harry H S; Pezzuto John M; Swanson Steven M; de Blanco Esperanza J Carcache; Kinghorn A Douglas
Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes.

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All Publications

2009: Endringer Denise C; Pezzuto John M; Braga Fernão C
NF-kappaB inhibitory activity of cyclitols isolated from Hancornia speciosa.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2009;16(11):1064-9.
2009: Pezzuto John M; Venkatasubramanian Venkat; Hamad Mazen; Morris Kenneth R
Unraveling the relationship between grapes and health.
The Journal of nutrition 2009;139(9):1783S-7S.
2009: Deng Ye; Balunas Marcy J; Kim Jeong-Ah; Lantvit Daniel D; Chin Young-Won; Chai Heebyung; Sugiarso Sugeng; Kardono Leonardus B S; Fong Harry H S; Pezzuto John M; Swanson Steven M; de Blanco Esperanza J Carcache; Kinghorn A Douglas
Bioactive 5,6-dihydro-alpha-pyrone derivatives from Hyptis brevipes.
Journal of natural products 2009;72(6):1165-9.
2009: Maiti Arup; Reddy P V Narasimha; Sturdy Megan; Marler Laura; Pegan Scott D; Mesecar Andrew D; Pezzuto John M; Cushman Mark
Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities.
Journal of medicinal chemistry 2009;52(7):1873-84.
2009: Mi Qiuwen; Pezzuto John M; Farnsworth Norman R; Wani Mansukh C; Kinghorn A Douglas; Swanson Steven M
Use of the in vivo hollow fiber assay in natural products anticancer drug discovery (#).
Journal of natural products 2009;72(3):573-80.
2009: Kang Soo Sung; Cuendet Muriel; Endringer Denise C; Croy Vicki L; Pezzuto John M; Lipton Mark A
Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB.
Bioorganic & medicinal chemistry 2009;17(3):1044-54.
2008: Cuendet Muriel; Oteham Carol P; Maiti Arup; Craig Bruce A; Cushman Mark; Moon Richard C; Pezzuto John M
Zapotin prevents mouse skin tumorigenesis during the stages of initiation and promotion.
Anticancer research 2008;28(6A):3705-9.
2008: Guo Jian; Liu Ang; Cao Hongmei; Luo Yan; Pezzuto John M; van Breemen Richard B
Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(10):2104-12.
2008: Francy-Guilford Jacquelyn; Pezzuto John M
Mechanisms of cancer chemopreventive agents: a perspective.
Planta medica 2008;74(13):1644-50.
2008: Guilford Jacquelyn M; Pezzuto John M
Natural products as inhibitors of carcinogenesis.
Expert opinion on investigational drugs 2008;17(9):1341-52.
2008: Pezzuto John M
Grapes and human health: a perspective.
Journal of agricultural and food chemistry 2008;56(16):6777-84.
2008: Endringer Denise C; Guimarães Keller G; Kondratyuk Tamara P; Pezzuto John M; Braga Fernão C
Selective inhibition of aromatase by a dihydroisocoumarin from Xyris pterygoblephara.
Journal of natural products 2008;71(6):1082-4.
2008: Guo Jian; Liu Dongting; Nikolic Dejan; Zhu Dongwei; Pezzuto John M; van Breemen Richard B
In vitro metabolism of isoliquiritigenin by human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(2):461-8.
2007: Liu Dongting; Guo Jian; Luo Yan; Broderick David J; Schimerlik Michael I; Pezzuto John M; van Breemen Richard B
Screening for ligands of human retinoid X receptor-alpha using ultrafiltration mass spectrometry.
Analytical chemistry 2007;79(24):9398-402.
2007: Maiti Arup; Cuendet Muriel; Croy Vicki L; Endringer Denise C; Pezzuto John M; Cushman Mark
Synthesis and biological evaluation of (+/-)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer.
Journal of medicinal chemistry 2007;50(12):2799-806.
2007: Williams Philip G; Asolkar Ratnakar N; Kondratyuk Tamara; Pezzuto John M; Jensen Paul R; Fenical William
Saliniketals A and B, bicyclic polyketides from the marine actinomycete Salinispora arenicola.
Journal of natural products 2007;70(1):83-8.
2007: Maiti Arup; Cuendet Muriel; Kondratyuk Tamara; Croy Vicki L; Pezzuto John M; Cushman Mark
Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis.
Journal of medicinal chemistry 2007;50(2):350-5.
2007: Murillo Genoveva; Hirschelman Wendy H; Ito Aiko; Moriarty Robert M; Kinghorn A Douglas; Pezzuto John M; Mehta Rajendra G
Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis.
Nutrition and cancer 2007;57(1):28-37.
2006: Choi Juliana K; Murillo Genoveva; Su Bao-Ning; Pezzuto John M; Kinghorn A D; Mehta Rajendra G
Ixocarpalactone A isolated from the Mexican tomatillo shows potent antiproliferative and apoptotic activity in colon cancer cells.
The FEBS journal 2006;273(24):5714-23.
2006: Balunas Marcy J; Jones William P; Chin Young-Won; Mi Qiuwen; Farnsworth Norman R; Soejarto Djaja D; Cordell Geoffrey A; Swanson Steven M; Pezzuto John M; Chai Hee-Byung; Kinghorn A Douglas
Relationships between inhibitory activity against a cancer cell line panel, profiles of plants collected, and compound classes isolated in an anticancer drug discovery project.
Chemistry & biodiversity 2006;3(8):897-915.
2006: Wright Anthony D; de Nys Rocky; Angerhofer Cindy K; Pezzuto John M; Gurrath Marion
Biological activities and 3D QSAR studies of a series of Delisea pulchra (cf. fimbriata) derived natural products.
Journal of natural products 2006;69(8):1180-7.
2006: Jang Dae Sik; Su Bao-Ning; Pawlus Alison D; Kang Young-Hwa; Kardono Leonardus B S; Riswan Soedarsono; Afriastini Johar J; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Beccaridiol, an unusual 28-nortriterpenoid from the leaves of Diplectria beccariana.
Phytochemistry 2006;67(16):1832-7.
2006: He Zhen-Dan; Ma Cui-Ying; Tan Ghee Teng; Sydara Kongmany; Tamez Pamela; Southavong Bounhoong; Bouamanivong Somsanith; Soejarto D Doel; Pezzuto John M; Fong Harry H S; Zhang Hong-Jie
Rourinoside and rouremin, antimalarial constituents from Rourea minor.
Phytochemistry 2006;67(13):1378-84.
2006: Gills Joell J; Jeffery Elizabeth H; Matusheski Nathan V; Moon Richard C; Lantvit Daniel D; Pezzuto John M
Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion.
Cancer letters 2006;236(1):72-9.
2006: Carcache-Blanco Esperanza J; Cuendet Muriel; Park Eun Jung; Su Bao-Ning; Rivero-Cruz J Fausto; Farnsworth Norman R; Pezzuto John M; Douglas Kinghorn A
Potential cancer chemopreventive agents from Arbutus unedo.
Natural product research 2006;20(4):327-34.
2006: Soejarto Djaja Doel; Zhang Hong Jie; Fong Harry H S; Tan Ghee T; Ma Cui Ying; Gyllenhaal Charlotte; Riley Mary C; Kadushin Marian R; Franzblau Scott G; Bich Truong Quang; Cuong Nguyen Manh; Hiep Nguyen Tien; Loc Phan Ke; Xuan Le Thi; Hai Nong Van; Hung Nguyen Van; Chien Nguyen Quyet; Binh Le Tran; Vu Bui Minh; Ly Ho Minh; Southavong Bounhong; Sydara Kongmany; Bouamanivong S; Pezzuto John M; Rose William C; Dietzman Gregg R; Miller Byron E; Thuy Tran Van
"Studies on biodiversity of Vietnam and Laos" 1998-2005: examining the impact.
Journal of natural products 2006;69(3):473-81.
2006: Cuendet Muriel; Oteham Carol P; Moon Richard C; Pezzuto John M
Quinone reductase induction as a biomarker for cancer chemoprevention.
Journal of natural products 2006;69(3):460-3.
2006: Homhual Sudarat; Bunyapraphatsara Nuntavan; Kondratyuk Tamara; Herunsalee Angkana; Chaukul Wongsatit; Pezzuto John M; Fong Harry H S; Zhang Hong-Jie
Bioactive dammarane triterpenes from the mangrove plant Bruguiera gymnorrhiza.
Journal of natural products 2006;69(3):421-4.
2006: Fang Liqiong; Ito Aiko; Chai Hee-Byung; Mi Qiuwen; Jones William P; Madulid Domingo R; Oliveros Mildred B; Gao Qi; Orjala Jimmy; Farnsworth Norman R; Soejarto Djaja D; Cordell Geoffrey A; Swanson Steven M; Pezzuto John M; Kinghorn A Douglas
Cytotoxic constituents from the stem bark of Dichapetalum gelonioides collected in the Philippines.
Journal of natural products 2006;69(3):332-7.
2006: Homhual Sudarat; Zhang Hong-Jie; Bunyapraphatsara Nuntavan; Kondratyuk Tamara P; Santarsiero Bernard D; Mesecar Andrew D; Herunsalee Angkana; Chaukul Wongsatit; Pezzuto John M; Fong Harry H
Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza.
Planta medica 2006;72(3):255-60.
2006: Zhang Hong-Jie; Ma Cuiying; Nguyen Van Hung; Nguyen Manh Cuong; Tan Ghee Teng; Santarsiero Bernard D; Mesecar Andrew D; Soejarto D Doel; Pezzuto John M; Fong Harry H S
Miliusanes, a class of cytotoxic agents from Miliusa sinensis.
Journal of medicinal chemistry 2006;49(2):693-708.
2006: Cuendet Muriel; Mesecar Andrew D; DeWitt David L; Pezzuto John M
An ELISA method to measure inhibition of the COX enzymes.
Nature protocols 2006;1(4):1915-21.
2006: Thole Julie M; Kraft Tristan F Burns; Sueiro Lilly Ann; Kang Young-Hwa; Gills Joell J; Cuendet Muriel; Pezzuto John M; Seigler David S; Lila Mary Ann
A comparative evaluation of the anticancer properties of European and American elderberry fruits.
Journal of medicinal food 2006;9(4):498-504.
2005: Lee Ho-Young; Oh Seung-Hyun; Woo Jong K; Kim Woo-Young; Van Pelt Carolyn S; Price Roger E; Cody Dianna; Tran Hai; Pezzuto John M; Moriarty Robert M; Hong Waun Ki
Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis.
Journal of the National Cancer Institute 2005;97(22):1695-9.
2005: He Zhen-Dan; Ma Cui-Ying; Zhang Hong-Jie; Tan Ghee Teng; Tamez Pamela; Sydara Kongmany; Bouamanivong S; Southavong Bounhoong; Soejarto Djaja D; Pezzuto John M; Fong Harry H S
Antimalarial constituents from Nauclea orientalis (L.) L.
Chemistry & biodiversity 2005;2(10):1378-86.
2005: Liu Guowen; Eggler Aimee L; Dietz Birgit M; Mesecar Andrew D; Bolton Judy L; Pezzuto John M; van Breemen Richard B
Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1.
Analytical chemistry 2005;77(19):6407-14.
2005: Koch A; Tamez P; Pezzuto J; Soejarto D
Evaluation of plants used for antimalarial treatment by the Maasai of Kenya.
Journal of ethnopharmacology 2005;101(1-3):95-9.
2005: Jones William P; Lobo-Echeverri Tatiana; Mi Qiuwen; Chai Heebyung; Lee Dongho; Soejarto Djaja D; Cordell Geoffrey A; Pezzuto John M; Swanson Steven M; Kinghorn A Douglas
Antitumour activity of 3-chlorodeoxylapachol, a naphthoquinone from Avicennia germinans collected from an experimental plot in southern Florida.
The Journal of pharmacy and pharmacology 2005;57(9):1101-8.
2005: Chow A W; Murillo G; Yu C; van Breemen R B; Boddie A W; Pezzuto J M; Das Gupta T K; Mehta R G
Resveratrol inhibits rhabdomyosarcoma cell proliferation.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2005;14(4):351-6.
2005: Soejarto D D; Fong H H S; Tan G T; Zhang H J; Ma C Y; Franzblau S G; Gyllenhaal C; Riley M C; Kadushin M R; Pezzuto J M; Xuan L T; Hiep N T; Hung N V; Vu B M; Loc P K; Dac L X; Binh L T; Chien N Q; Hai N V; Bich T Q; Cuong N M; Southavong B; Sydara K; Bouamanivong S; Ly H M; Thuy Tran Van; Rose W C; Dietzman G R
Ethnobotany/ethnopharmacology and mass bioprospecting: issues on intellectual property and benefit-sharing.
Journal of ethnopharmacology 2005;100(1-2):15-22.
2005: Jang Dae Sik; Su Bao-Ning; Pawlus Alison D; Jones William P; Kleps Robert A; Bunyapraphatsara Nuntavan; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Limnophilaspiroketone, a highly oxygenated phenolic derivative from Limnophila geoffrayi.
Journal of natural products 2005;68(7):1134-6.
2005: Eggler Aimee L; Liu Guowen; Pezzuto John M; van Breemen Richard B; Mesecar Andrew D
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(29):10070-5.
2005: Gills J J; Kosmeder J; Moon R C; Lantvit D D; Pezzuto J M
Effect of deguelin on UVB-induced skin carcinogenesis.
Journal of chemotherapy (Florence, Italy) 2005;17(3):297-301.
2005: Zhang Hong-Jie; Nguyen Van Hung; Nguyen Manh Cuong; Soejarto D Doel; Pezzuto John M; Fong Harry H; Tan Ghee Teng
Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata.
Planta medica 2005;71(5):452-7.
2005: Lobo-Echeverri Tatiana; Rivero-Cruz J Fausto; Su Bao-Ning; Chai Hee-Byung; Cordell Geoffrey A; Pezzuto John M; Swanson Steven M; Soejarto D Doel; Kinghorn A Douglas
Constituents of the leaves and twigs of Calyptranthes pallens collected from an experimental plot in Southern Florida.
Journal of natural products 2005;68(4):577-80.
2005: Tamez Pamela A; Lantvit Dan; Lim Eulenia; Pezzuto John M
Chemosensitizing action of cepharanthine against drug-resistant human malaria, Plasmodium falciparum.
Journal of ethnopharmacology 2005;98(1-2):137-42.
2005: Mi Qiuwen; Lantvit Daniel; Reyes-Lim Eulenia; Chai Heebyung; Phifer Sharnelle S; Wani Mansukh C; Wall Monroe E; Tan Ghee T; Cordell Geoffrey A; Farnsworth Norman R; Kinghorn A Douglas; Pezzuto John M
Apoptotic anticancer effect of alvaradoin E isolated from Alvaradoa haitiensis.
Anticancer research 2005;25(2A):779-87.
2005: Rivero-Cruz J Fausto; Lezutekong Raphael; Lobo-Echeverri Tatiana; Ito Aiko; Mi Qiuwen; Chai Hee-Byung; Soejarto Djaja D; Cordell Geoffrey A; Pezzuto John M; Swanson Steven M; Morelli Ivano; Kinghorn A Douglas
Cytotoxic constituents of the twigs of Simarouba glauca collected from a plot in Southern Florida.
Phytotherapy research : PTR 2005;19(2):136-40.
2004: Su Bao-Ning; Jones William P; Cuendet Muriel; Kardono Leonardus B S; Ismail Rachman; Riswan Soedarsono; Fong Harry H S; Farnsworth Norman R; Pezzuto John M; Kinghorn A Douglas
Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and -2.
Phytochemistry 2004;65(21):2861-6.
2004: Gafner Stefan; Lee Sang-Kook; Cuendet Muriel; Barthélémy Sophie; Vergnes Laurent; Labidalle Serge; Mehta Rajendra G; Boone Charles W; Pezzuto John M
Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems.
Phytochemistry 2004;65(21):2849-59.
2004: Jang Dae Sik; Cuendet Muriel; Su Bao-Ning; Totura Steven; Riswan Soedarsono; Fong Harry H; Pezzuto John M; Kinghorn A Douglas
Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2.
Planta medica 2004;70(10):893-6.
2004: Pezzuto John M
Resveratrol: a whiff that induces a biologically specific tsunami.
Cancer biology & therapy 2004;3(9):889-90.
2004: Kinghorn A Douglas; Su Bao-Ning; Jang Dae Sik; Chang Leng Chee; Lee Dongho; Gu Jian-Qiao; Carcache-Blanco Esperanza J; Pawlus Alison D; Lee Sang Kook; Park Eun Jung; Cuendet Muriel; Gills Joell J; Bhat Krishna; Park Hye-Sung; Mata-Greenwood Eugenia; Song Lynda L; Jang Meishiang; Pezzuto John M
Natural inhibitors of carcinogenesis.
Planta medica 2004;70(8):691-705.
2004: Gu Jian-Qiao; Graf Tyler N; Lee Dongho; Chai Hee-Byung; Mi Qiuwen; Kardono Leonardus B S; Setyowati Fransisca M; Ismail Rachman; Riswan Soedarsono; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Swanson Steven M; Kroll David J; Falkinham Joseph O; Wall Monroe E; Wani Mansukh C; Kinghorn A Douglas; Oberlies Nicholas H
Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia.
Journal of natural products 2004;67(7):1156-61.
2004: Li Y; Grubjesic S; Nikolic D; Zhu D; Kosmeder J W; Moriarty R M; Pezzuto J M; Van Breemen R B
In vitro assessment of intestinal permeability and hepatic metabolism of 4'-bromoflavone, a promising cancer chemopreventive agent.
Xenobiotica; the fate of foreign compounds in biological systems 2004;34(6):535-47.
2004: Nguyen Quyet Chien; Nguyen Van Hung; Santarsiero Bernard D; Mesecar Andrew D; Nguyen Manh Cuon; Soejarto D Doel; Pezzuto John M; Fong Harry H S; Tan Ghee T
New 3-O-acyl betulinic acids from Strychnos vanprukii Craib.
Journal of natural products 2004;67(6):994-8.
2004: Christov K T; Moon R C; Lantvit D D; Boone C W; Kelloff G J; Steele V E; Lubet R A; Pezzuto J M
Prostate intraepithelial neoplasia in Noble rats, a potential intermediate endpoint for chemoprevention studies.
European journal of cancer (Oxford, England : 1990) 2004;40(9):1404-11.
2004: Hwang Bang Yeon; Su Bao-Ning; Chai Heebyung; Mi Qiuwen; Kardono Leonardus B S; Afriastini Johar J; Riswan Soedarsono; Santarsiero Bernard D; Mesecar Andrew D; Wild Robert; Fairchild Craig R; Vite Gregory D; Rose William C; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Swanson Steven M; Kinghorn A Douglas
Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris.
The Journal of organic chemistry 2004;69(10):3350-8.
2004: Jang Dae Sik; Cuendet Muriel; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Constituents of Asparagus officinalis evaluated for inhibitory activity against cyclooxygenase-2.
Journal of agricultural and food chemistry 2004;52(8):2218-22.
2004: Diaz Fredyc; Chai Hee-Byung; Mi Qiuwen; Su Bao-Ning; Vigo Jose Schunke; Graham James G; Cabieses Fernando; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Swanson Steven M; Kinghorn A Douglas
Anthrone and oxanthrone C-glycosides from Picramnia latifolia collected in Peru.
Journal of natural products 2004;67(3):352-6.
2004: Rivero-Cruz J Fausto; Chai Hee-Byung; Kardono Leonardus B S; Setyowati Fransisca M; Afriatini Johar J; Riswan Soedarsano; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Swanson Steven M; Kinghorn A Douglas
Cytotoxic constituents of the twigs and leaves of Aglaia rubiginosa.
Journal of natural products 2004;67(3):343-7.
2004: Cuendet Muriel; Gills Joell J; Pezzuto John M
Brusatol-induced HL-60 cell differentiation involves NF-kappaB activation.
Cancer letters 2004;206(1):43-50.
2004: Jang Dae Sik; Park Eun Jung; Kang Young-Hwa; Vigo Jose Schunke; Graham James G; Cabieses Fernando; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Phenolic compounds obtained from stems of Couepia ulei with the potential to induce quinone reductase.
Archives of pharmacal research 2004;27(2):169-72.
2004: Soejarto D D; Gyllenhaal C; Fong H H S; Xuan L T; Hiep N T; Hung N V; Bich T Q; Southavong B; Sydara K; Pezzuto J M
The UIC ICBG (University of Illinois at Chicago International Cooperative Biodiversity Group) Memorandum of Agreement: a model of benefit-sharing arrangement in natural products drug discovery and development.
Journal of natural products 2004;67(2):294-9.
2004: Cuendet Muriel; Pezzuto John M
Antitumor activity of bruceantin: an old drug with new promise.
Journal of natural products 2004;67(2):269-72.
2004: Ito Aiko; Chai Hee-Byung; Kardono Leonardus B S; Setowati Francisca M; Afriastini Johar J; Riswan Soedarsono; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Swanson Steven M; Kinghorn A Douglas
Saponins from the bark of Nephelium maingayi.
Journal of natural products 2004;67(2):201-5.
2004: Zhang Hong-Jie; Sydara Kongmany; Tan Ghee Teng; Ma Cuiying; Southavong Bounhoong; Soejarto D Doel; Pezzuto John M; Fong Harry H S
Bioactive constituents from Asparagus cochinchinensis.
Journal of natural products 2004;67(2):194-200.
2004: Cuendet Muriel; Christov Konstantin; Lantvit Daniel D; Deng Yunfan; Hedayat Samad; Helson Lawrence; McChesney James D; Pezzuto John M
Multiple myeloma regression mediated by bruceantin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(3):1170-9.
2004: Lee Ho-Young; Suh Young-Ah; Kosmeder Jerome W; Pezzuto John M; Hong Waun Ki; Kurie Jonathan M
Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(3):1074-9.
2004: Jang Dae Sik; Cuendet Muriel; Pawlus Alison D; Kardono Leonardus B S; Kawanishi Kazuko; Farnsworth Norman R; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Potential cancer chemopreventive constituents of the leaves of Macaranga triloba.
Phytochemistry 2004;65(3):345-50.
2004: Liu J; Burdette J E; Sun Y; Deng S; Schlecht S M; Zheng W; Nikolic D; Mahady G; van Breemen R B; Fong H H S; Pezzuto J M; Bolton J L; Farnsworth N R
Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry).
Phytomedicine : international journal of phytotherapy and phytopharmacology 2004;11(1):18-23.
2004: Kang Young-Hwa; Pezzuto John M
Induction of quinone reductase as a primary screen for natural product anticarcinogens.
Methods in enzymology 2004;382():380-414.
2003: Li Yongmei; Shin Young Geun; Yu Chongwoo; Kosmeder Jerome W; Hirschelman Wendy H; Pezzuto John M; van Breemen Richard B
Increasing the throughput and productivity of Caco-2 cell permeability assays using liquid chromatography-mass spectrometry: application to resveratrol absorption and metabolism.
Combinatorial chemistry & high throughput screening 2003;6(8):757-67.
2003: Topcu Gulaçti; Aydogmus Zeynep; Imre Sedat; Gören Ahmet C; Pezzuto John M; Clement Jason A; Kingston David G I
Brominated sesquiterpenes from the red alga Laurencia obtusa.
Journal of natural products 2003;66(11):1505-8.
2003: Mi Qiuwen; Cui Baoliang; Lantvit Daniel; Reyes-Lim Eulenia; Chai Heebyung; Pezzuto John M; Kinghorn A Douglas; Swanson Steven M
Pervilleine F, a new tropane alkaloid aromatic ester that reverses multidrug resistance.
Anticancer research 2003;23(5A):3607-15.
2003: Carcache-Blanco Esperanza J; Kang Young-Hwa; Park Eun Jung; Su Bao-Ning; Kardono Leonardus B S; Riswan Soedarsono; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase.
Journal of natural products 2003;66(9):1197-202.
2003: Jang Dae Sik; Park Eun Jung; Kang Young-Hwa; Hawthorne Michael E; Vigo Jose Schunke; Graham James G; Cabieses Fernando; Fong Harry H S; Mehta Rajendra G; Pezzuto John M; Kinghorn A Douglas
Potential cncer chemopreventive flavonoids from the stems of Tephrosia toxicaria.
Journal of natural products 2003;66(9):1166-70.
2003: Burdette Joanna E; Liu Jianghua; Chen Shao-Nong; Fabricant Daniel S; Piersen Colleen E; Barker Eric L; Pezzuto John M; Mesecar Andrew; Van Breemen Richard B; Farnsworth Norman R; Bolton Judy L
Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor.
Journal of agricultural and food chemistry 2003;51(19):5661-70.
2003: Su Bao-Ning; Kang Young-Hwa; Pinos Rosa Elena; Santarsiero Bernard D; Mesecar Andrew D; Soejarto D Doel; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Isolation and absolute stereochemistry of coussaric acid, a new bioactive triterpenoid from the stems of Coussarea brevicaulis.
Phytochemistry 2003;64(1):293-302.
2003: Lee Kyung-Hee; Chai Hee-Byung; Tamez Pamela A; Pezzuto John M; Cordell Geoffrey A; Win Khin Khin; Tin-Wa Maung
Biologically active alkylated coumarins from Kayea assamica.
Phytochemistry 2003;64(2):535-41.
2003: Jang Dae Sik; Park Eun Jung; Kang Young-Hwa; Su Bao-Ning; Hawthorne Michael E; Vigo Jose Schunke; Graham James G; Cabieses Fernando; Fong Harry H S; Mehta Rajendra G; Pezzuto John M; Kinghorn A Douglas
Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model.
Archives of pharmacal research 2003;26(8):585-90.
2003: Su Bao-Ning; Park Eun Jung; Nikolic Dejan; Schunke Vigo Jose; Graham James G; Cabieses Fernando; van Breemen Richard B; Fong Harry H S; Farnsworth Norman R; Pezzuto John M; Kinghorn A Douglas
Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora.
Journal of natural products 2003;66(8):1089-93.
2003: Tan YingMeei; Yu Rong; Pezzuto John M
Betulinic acid-induced programmed cell death in human melanoma cells involves mitogen-activated protein kinase activation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2866-75.
2003: Díaz Fredyc; Chávez Daniel; Lee Dongho; Mi Qiuwen; Chai Hee-Byung; Tan Ghee T; Kardono Leonardus B S; Riswan Soedarsono; Fairchild Craig R; Wild Robert; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Kinghorn A Douglas
Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo.
Journal of natural products 2003;66(6):865-7.
2003: Su Bao-Ning; Jung Park Eun; Vigo Jose Schunke; Graham James G; Cabieses Fernando; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay.
Phytochemistry 2003;63(3):335-41.
2003: Topcu Gulacti; Altiner Esra N; Gozcu Seyda; Halfon Belkis; Aydogmus Zeynep; Pezzuto J M; Zhou Bing-Nan; Kingston David G
Studies on di- and triterpenoids from Salvia staminea with cytotoxic activity.
Planta medica 2003;69(5):464-7.
2003: Zhang Hong-Jie; Tan Ghee Teng; Santarsiero Bernard D; Mesecar Andrew D; Hung Nguyen Van; Cuong Nguyen Manh; Doel Soejarto D; Pezzuto John M; Fong Harry H S
New Sesquiterpenes from Litsea verticillata.
Journal of natural products 2003;66(5):609-15.
2003: Jang Dae Sik; Park Eun Jung; Hawthorne Michael E; Vigo Jose Schunke; Graham James G; Cabieses Fernando; Santarsiero Bernard D; Mesecar Andrew D; Fong Harry H S; Mehta Rajendra G; Pezzuto John M; Kinghorn A Douglas
Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean).
Journal of natural products 2003;66(5):583-7.
2003: Fang Liqiong; Chai Hee-Byung; Castillo Juan J; Soejarto Djaja D; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Kinghorn A Douglas
Cytotoxic constituents of Brachistus stramoniifolius.
Phytotherapy research : PTR 2003;17(5):520-3.
2003: Gu Jian-Qiao; Li Wenkui; Kang Young-Hwa; Su Bao-Ning; Fong Harry H S; van Breemen Richard B; Pezzuto John M; Kinghorn A Douglas
Minor withanolides from Physalis philadelphica: structures, quinone reductase induction activities, and liquid chromatography (LC)-MS-MS investigation as artifacts.
Chemical & pharmaceutical bulletin 2003;51(5):530-9.
2003: Gafner Stefan; Bergeron Chantal; Batcha Laura L; Reich Jesse; Arnason John T; Burdette Joanna E; Pezzuto John M; Angerhofer Cindy K
Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora.
Journal of natural products 2003;66(4):535-7.
2003: Su Bao-Ning; Park Eun Jung; Nikolic Dejan; Santarsiero Bernard D; Mesecar Andrew D; Vigo Jose Schunke; Graham James G; Cabieses Fernando; van Breemen Richard B; Fong Harry H S; Farnsworth Norman R; Pezzuto John M; Kinghorn A Douglas
Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity.
The Journal of organic chemistry 2003;68(6):2350-61.
2003: Murillo Genoveva; Kosmeder Jerome W; Pezzuto John M; Mehta Rajendra G
Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice.
International journal of cancer. Journal international du cancer 2003;104(1):7-11.
2003: Seo Eun-Kyoung; Lee Dongho; Shin Young Geun; Chai Hee-Byung; Navarro Hernán A; Kardono Leonardus B S; Rahman Ismail; Cordell Geoffrey A; Farnsworth Norman R; Pezzuto John M; Kinghorn A Douglas; Wani Mansukh C; Wall Monroe E
Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando.
Archives of pharmacal research 2003;26(2):124-7.
2003: Zhang Hong-Jie; Tan Ghee Teng; Hoang Vu Dinh; Hung Nguyen Van; Cuong Nguyen Manh; Soejarto D Doel; Pezzuto John M; Fong Harry H S
Natural anti-HIV agents. Part IV. Anti-HIV constituents from Vatica cinerea.
Journal of natural products 2003;66(2):263-8.
2003: Chun Kyung-Hee; Kosmeder Jerome W; Sun Shihua; Pezzuto John M; Lotan Reuben; Hong Waun Ki; Lee Ho-Young
Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells.
Journal of the National Cancer Institute 2003;95(4):291-302.
2003: Duncan Christine J G; Cuendet Muriel; Fronczek Frank R; Pezzuto John M; Mehta Rajendra G; Hamann Mark T; Ross Samir A
Chemical and biological investigation of the fungus Pulveroboletus ravenelii.
Journal of natural products 2003;66(1):103-7.
2003: Hwang Bang Yeon; Chai Hee-Byung; Kardono Leonardus B S; Riswan Soedarsono; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Kinghorn A Douglas
Cytotoxic triterpenes from the twigs of Celtis philippinensis.
Phytochemistry 2003;62(2):197-201.
2003: Omar S; Zhang J; MacKinnon S; Leaman D; Durst T; Philogene B J R; Arnason J T; Sanchez-Vindas P E; Poveda L; Tamez P A; Pezzuto J M
Traditionally-used antimalarials from the Meliaceae.
Current topics in medicinal chemistry 2003;3(2):133-9.
2003: Yu Chongwoo; Shin Young Geun; Kosmeder Jerome W; Pezzuto John M; van Breemen Richard B
Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate.
Rapid communications in mass spectrometry : RCM 2003;17(4):307-13.
2002: Xu H; Fabricant D S; Piersen C E; Bolton J L; Pezzuto J M; Fong H; Totura S; Farnsworth N R; Constantinou A I
A preliminary RAPD-PCR analysis of Cimicifuga species and other botanicals used for women's health.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2002;9(8):757-62.
2002: Yu Chongwoo; Shin Young Geun; Chow Anita; Li Yongmei; Kosmeder Jerome W; Lee Yong Sup; Hirschelman Wendy H; Pezzuto John M; Mehta Rajendra G; van Breemen Richard B
Human, rat, and mouse metabolism of resveratrol.
Pharmaceutical research 2002;19(12):1907-14.
2002: Calderón Angela I; Terreaux Christian; Schenk Kurt; Pattison Phil; Burdette Joanna E; Pezzuto John M; Gupta Mahabir P; Hostettmann K
Isolation and structure elucidation of an isoflavone and a sesterterpenoic acid from Henriettella fascicularis.
Journal of natural products 2002;65(12):1749-53.
2002: Su Bao-Ning; Cuendet Muriel; Farnsworth Norman R; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Activity-guided fractionation of the seeds of Ziziphus jujuba using a cyclooxygenase-2 inhibitory assay.
Planta medica 2002;68(12):1125-8.
2002: Zhang Hong-Jie; Tamez Pamela A; Aydogmus Zeynep; Tan Ghee Teng; Saikawa Yoko; Hashimoto Kimiko; Nakata Masaya; Hung Nguyen Van; Xuan Le Thi; Cuong Nguyen Manh; Soejarto D Doel; Pezzuto John M; Fong Harry H S
Antimalarial agents from plants. III. Trichothecenes from Ficus fistulosa and Rhaphidophora decursiva.
Planta medica 2002;68(12):1088-91.
2002: Murillo G; Salti G I; Kosmeder J W; Pezzuto J M; Mehta R G
Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest.
European journal of cancer (Oxford, England : 1990) 2002;38(18):2446-54.
2002: Jang Dae Sik; Cuendet Muriel; Hawthorne Michael E; Kardono Leonardus B S; Kawanishi Kazuko; Fong Harry H S; Mehta Rajendra G; Pezzuto John M; Kinghorn A Douglas
Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2.
Phytochemistry 2002;61(7):867-72.
2002: Verotta Luisella; Guerrini Marco; El-Sebakhy Nadia A; Assad Aya M; Toaima Soad M; Radwan Mohamed M; Luo Ying-De; Pezzuto John M
Cycloartane and oleanane saponins from egyptian astragalus spp. as modulators of lymphocyte proliferation.
Planta medica 2002;68(11):986-94.
2002: Gu Jian-Qiao; Park Eun Jung; Vigo Jose Schunke; Graham James G; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase.
Journal of natural products 2002;65(11):1616-20.
2002: Burdette Joanna E; Chen Shao-Nong; Lu Zhi-Zhen; Xu Haiyan; White Bethany E P; Fabricant Daniel S; Liu Jianghua; Fong Harry H S; Farnsworth Norman R; Constantinou Andreas I; Van Breemen Richard B; Pezzuto John M; Bolton Judy L
Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles.
Journal of agricultural and food chemistry 2002;50(24):7022-8.
2002: Mata-Greenwood E; Cuendet M; Sher D; Gustin D; Stock W; Pezzuto J M
Brusatol-mediated induction of leukemic cell differentiation and G(1) arrest is associated with down-regulation of c-myc.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(11):2275-84.
2002: Mehta Rajendra G; Pezzuto John M
Discovery of cancer preventive agents from natural products: from plants to prevention.
Current oncology reports 2002;4(6):478-86.
2002: Jang Dae Sik; Park Eun Jung; Hawthorne Michael E; Vigo Jose Schunke; Graham James G; Cabieses Fernando; Santarsiero Bernard D; Mesecar Andrew D; Fong Harry H S; Mehta Rajendra G; Pezzuto John M; Kinghorn A Douglas
Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase.
Journal of agricultural and food chemistry 2002;50(22):6330-4.
2002: Mi Qiuwen; Cui Baoliang; Silva Gloria L; Lantvit Daniel; Lim Eula; Chai Heebyung; Hollingshead Melinda G; Mayo Joseph G; Kinghorn A Douglas; Pezzuto John M
Pervilleines B and C, new tropane alkaloid aromatic esters that reverse the multidrug-resistance in the hollow fiber assay.
Cancer letters 2002;184(1):13-20.
2002: Gören Ahmet; Topçu Gülaçti; Bilsel Gökhan; Bilsel Mine; Aydogmus Zeynep; Pezzuto John M
The chemical constituents and biological activity of essential oil of Lavandula stoechas ssp. stoechas.
Zeitschrift für Naturforschung. C, Journal of biosciences 2002;57(9-10):797-800.
2002: Su Bao-Ning; Park Eun Jung; Mbwambo Zakaria H; Santarsiero Bernard D; Mesecar Andrew D; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
New chemical constituents of Euphorbia quinquecostata and absolute configuration assignment by a convenient Mosher ester procedure carried out in NMR tubes.
Journal of natural products 2002;65(9):1278-82.
2002: Christov Konstantin T; Moon Richard C; Lantvit Daniel D; Boone Charles W; Steele Vernon E; Lubet Ronald A; Kelloff Gary J; Pezzuto John M
9-cis-retinoic acid but not 4-(hydroxyphenyl)retinamide inhibits prostate intraepithelial neoplasia in Noble rats.
Cancer research 2002;62(18):5178-82.
2002: Ito Aiko; Chai Hee-Byung; Lee Dongho; Kardono Leonardus B S; Riswan Soedarsono; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Kinghorn A Douglas
Ellagic acid derivatives and cytotoxic cucurbitacins from Elaeocarpus mastersii.
Phytochemistry 2002;61(2):171-4.
2002: Su Bao-Ning; Chang Leng Chee; Park Eun Jung; Cuendet Muriel; Santarsiero Bernard D; Mesecar Andrew D; Mehta Rajendra G; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Bioactive constituents of the seeds of Brucea javanica.
Planta medica 2002;68(8):730-3.
2002: Gu Jian-Qiao; Park Eun Jung; Totura Stephen; Riswan Soedarsono; Fong Harry H S; Pezzuto John M; Kinghorn A Douglas
Constituents of the twigs of Hernandia ovigera that inhibit the transformation of JB6 murine epidermal cells.
Journal of natural products 2002;65(7):1065-8.
2002: Blatt Cecília T T; Chávez Daniel; Chai Heebyung; Graham James G; Cabieses Fernando; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Kinghorn A Douglas
Cytotoxic flavonoids from the stem bark of Lonchocarpus aff. fluvialis.
Phytotherapy research : PTR 2002;16(4):320-5.
2002: Mi Qiuwen; Lantvit Daniel; Reyes-Lim Eulenia; Chai Heebyung; Zhao Weimin; Lee Ik-Soo; Peraza-Sánchez Sergio; Ngassapa Olipa; Kardono Leonardus B S; Riswan Soedarsono; Hollingshead Melinda G; Mayo Joseph G; Farnsworth Norman R; Cordell Geoffrey A; Kinghorn A Douglas; Pezzuto John M
Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.
Journal of natural products 2002;65(6):842-50.
2002: Rimando Agnes M; Cuendet Muriel; Desmarchelier Cristian; Mehta Rajendra G; Pezzuto John M; Duke Stephen O
Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol.
Journal of agricultural and food chemistry 2002;50(12):3453-7.
2002: Mi Qiuwen; Cui Baoliang; Chávez Daniel; Chai Heebyung; Zhu Haiyuan; Cordell Geoffrey A; Hedayat Sam; Kinghorn A Douglas; Pezzuto John M
Characterization of tropane alkaloid aromatic esters that reverse the multidrug-resistance phenotype.
Anticancer research 2002;22(3):1385-97.
2002: Bhat Krishna P L; Pezzuto John M
Cancer chemopreventive activity of resveratrol.
Annals of the New York Academy of Sciences 2002;957():210-29.
2002: Misico Rosana I; Song Lynda L; Veleiro Adriana S; Cirigliano Adriana M; Tettamanzi María C; Burton Gerardo; Bonetto Gloria M; Nicotra Viviana E; Silva Gloria L; Gil Roberto R; Oberti Juan C; Kinghorn A Douglas; Pezzuto John M
Induction of quinone reductase by withanolides.
Journal of natural products 2002;65(5):677-80.
2002: Chávez Daniel; Cui Baoliang; Chai Hee-Byung; García Ricardo; Mejía Miliciades; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Kinghorn A Douglas
Reversal of multidrug resistance by tropane alkaloids from the stems of Erythroxylum rotundifolium.
Journal of natural products 2002;65(4):606-10.
2002: Gu Jian-Qiao; Gills Joell J; Park Eun Jung; Mata-Greenwood Eugenia; Hawthorne Michael E; Axelrod Franklin; Chavez Pedro I; Fong Harry H S; Mehta Rajendra G; Pezzuto John M; Kinghorn A Douglas
Sesquiterpenoids from Tithonia diversifolia with potential cancer chemopreventive activity.
Journal of natural products 2002;65(4):532-6.
2002: Minguzzi Sandro; Barata Lauro E S; Shin Young Geun; Jonas Patrick F; Chai Hee Byung; Park Eun Jung; Pezzuto John M; Cordell Geoffrey A
Cytotoxic withanolides from Acnistus arborescens.
Phytochemistry 2002;59(6):635-41.
2002: Peraza-Sánchez Sergio R; Chai Hee-Byung; Shin Young Geun; Santisuk Thawatchai; Reutrakul Vichai; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Kinghorn A Douglas
Constituents of the leaves and twigs of Ficus hispida.
Planta medica 2002;68(2):186-8.
2002: Zhang Hongjie; Fan Zhuting; Tan Ghee T; Chai Hee-Byung; Pezzuto John M; Sun Handong; Fong Harry H S
Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata.
Journal of natural products 2002;65(2):215-7.
2002: Su Bao-Ning; Cuendet Muriel; Hawthorne Michael E; Kardono Leonardus B S; Riswan Soedarsono; Fong Harry H S; Mehta Rajendra G; Pezzuto John M; Kinghorn A Douglas
Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity.
Journal of natural products 2002;65(2):163-9.
2002: Kandil Fayez E; Smith Mary Ann L; Rogers Randy B; Pépin Marie-France; Song Lynda L; Pezzuto John M; Seigler David S
Composition of a chemopreventive proanthocyanidin-rich fraction from cranberry fruits responsible for the inhibition of 12-O-tetradecanoyl phorbol-13-acetate (TPA)-induced ornithine decarboxylase (ODC) activity.
Journal of agricultural and food chemistry 2002;50(5):1063-9.
2002: Hoang Vu Dinh; Tan Ghee Teng; Zhang Hong-Jie; Tamez Pamela A; Hung Nguyen Van; Cuong Nguyen Manh; Soejarto D Doel; Fong Harry H S; Pezzuto John M
Natural anti-HIV agents-part I: (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata.
Phytochemistry 2002;59(3):325-9.
2002: Lee Sang Kook; Heo Yoen Hoi; Steele Vernon E; Pezzuto John M
Induction of apoptosis by 1,4-phenylenebis(methylene)selenocyanate in cultured human colon cancer cells.
Anticancer research 2002;22(1A):97-102.
2002: Burdette Joanna E; Liu Jianghua; Lantvit Dan; Lim Eula; Booth Nancy; Bhat Krishna P L; Hedayat Samad; Van Breemen Richard B; Constantinou Andreas I; Pezzuto John M; Farnsworth Norman R; Bolton Judy L
Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats.
The Journal of nutrition 2002;132(1):27-30.
2002: Park Eun Jung; Pezzuto John M
Botanicals in cancer chemoprevention.
Cancer metastasis reviews 2002;21(3-4):231-55.
2002: Kosmeder J W; Pezzuto J M
Novel plant-derived anticarcinogens.
IARC scientific publications 2002;156():343-7.
2001: Bhat KPL; Kosmeder J W; Pezzuto J M
Biological effects of resveratrol.
Antioxidants & redox signaling 2001;3(6):1041-64.
2001: Bhat K P; Pezzuto J M
Natural modulators of estrogen biosynthesis and function as chemopreventive agents.
Archives of pharmacal research 2001;24(6):473-84.
2001: Silva G L; Cui B; Chávez D; You M; Chai H B; Rasoanaivo P; Lynn S M; O'Neill M J; Lewis J A; Besterman J M; Monks A; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
Modulation of the multidrug-resistance phenotype by new tropane alkaloid aromatic esters from Erythroxylum pervillei.
Journal of natural products 2001;64(12):1514-20.
2001: Mata-Greenwood E; Daeuble J F; Grieco P A; Dou J; McChesney J D; Mehta R G; Kinghorn A D; Pezzuto J M
Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture.
Journal of natural products 2001;64(12):1509-13.
2001: Verotta L; Guerrini M; El-Sebakhy N A; Asaad A M; Toaima S M; Abou-Sheer M E; Luo Y D; Pezzuto J M
Cycloartane saponins from Astragalus peregrinus as modulators of lymphocyte proliferation.
Fitoterapia 2001;72(8):894-905.
2001: Topçu G; Ayral M N; Aydin A; Gören A C; Chai H B; Pezzuto J M
Triterpenoids of the roots of Lavandula stoechas ssp. stoechas.
Die Pharmazie 2001;56(11):892-5.
2001: Seo E K; Kim N C; Mi Q; Chai H; Wall M E; Wani M C; Navarro H A; Burgess J P; Graham J G; Cabieses F; Tan G T; Farnsworth N R; Pezzuto J M; Kinghorn A D
Macharistol, a new cytotoxic cinnamylphenol from the stems of Machaerium aristulatum.
Journal of natural products 2001;64(11):1483-5.
2001: Lee D; Bhat K P; Fong H H; Farnsworth N R; Pezzuto J M; Kinghorn A D
Aromatase inhibitors from Broussonetia papyrifera.
Journal of natural products 2001;64(10):1286-93.
2001: Bhat K P; Lantvit D; Christov K; Mehta R G; Moon R C; Pezzuto J M
Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models.
Cancer research 2001;61(20):7456-63.
2001: Gu J Q; Park E J; Luyengi L; Hawthorne M E; Mehta R G; Farnsworth N R; Pezzuto J M; Kinghorn A D
Constituents of Eugenia sandwicensis with potential cancer chemopreventive activity.
Phytochemistry 2001;58(1):121-7.
2001: Tuchinda P; Pohmakotr M; Reutrakul V; Thanyachareon W; Sophasan S; Yoosook C; Santisuk T; Pezzuto J M
2-substituted furans from Polyalthia suberosa.
Planta medica 2001;67(6):572-5.
2001: Bhat K P; Pezzuto J M
Resveratrol exhibits cytostatic and antiestrogenic properties with human endometrial adenocarcinoma (Ishikawa) cells.
Cancer research 2001;61(16):6137-44.
2001: Mehta R G; Bhat K P; Hawthorne M E; Kopelovich L; Mehta R R; Christov K; Kelloff G J; Steele V E; Pezzuto J M
Induction of atypical ductal hyperplasia in mouse mammary gland organ culture.
Journal of the National Cancer Institute 2001;93(14):1103-6.
2001: Lee D; Cuendet M; Vigo J S; Graham J G; Cabieses F; Fong H H; Pezzuto J M; Kinghorn A D
A novel cyclooxygenase-inhibitory stilbenolignan from the seeds of Aiphanes aculeata.
Organic letters 2001;3(14):2169-71.
2001: Yu R; Hebbar V; Kim D W; Mandlekar S; Pezzuto J M; Kong A N
Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways.
Molecular pharmacology 2001;60(1):217-24.
2001: Zhang H J; Tamez P A; Vu D H; Ghee T T; Nguyen V H; Le T X; Le M H; Nguyen M C; Do T T; Soejarto D D; Fong H H; Pezzuto J M
Antimalarial compounds from Rhaphidophora decursiva.
Journal of natural products 2001;64(6):772-7.
2001: Lee D; Park E J; Cuendet M; Axelrod F; Chavez P I; Fong H H; Pezzuto J M; Kinghorn A D
Cyclooxygenase-inhibitory and antioxidant constituents of the aerial parts of Antirhea acutata.
Bioorganic & medicinal chemistry letters 2001;11(12):1565-8.
2001: Mata-Greenwood E; Ito A; Westenburg H; Cui B; Mehta R G; Kinghorn A D; Pezzuto J M
Discovery of novel inducers of cellular differentiation using HL-60 promyelocytic cells.
Anticancer research 2001;21(3B):1763-70.
2001: Liu J; Burdette J E; Xu H; Gu C; van Breemen R B; Bhat K P; Booth N; Constantinou A I; Pezzuto J M; Fong H H; Farnsworth N R; Bolton J L
Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms.
Journal of agricultural and food chemistry 2001;49(5):2472-9.
2001: Mi Q; Cui B; Silva G L; Lantvit D; Lim E; Chai H; You M; Hollingshead M G; Mayo J G; Kinghorn A D; Pezzuto J M
Pervilleine A, a novel tropane alkaloid that reverses the multidrug-resistance phenotype.
Cancer research 2001;61(10):4030-7.
2001: Park E J; Lee D; Shin Y G; Lantvit D D; van Breemen R B; Kinghorn A D; Pezzuto J M
Analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors using liquid chromatography-electrospray mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications 2001;754(2):327-32.
2001: Salti G I; Kichina J V; Das Gupta T K; Uddin S; Bratescu L; Pezzuto J M; Mehta R G; Constantinou A I
Betulinic acid reduces ultraviolet-C-induced DNA breakage in congenital melanocytic naeval cells: evidence for a potential role as a chemopreventive agent.
Melanoma research 2001;11(2):99-104.
2001: Correia S D; David J M; David J P; Chai H B; Pezzuto J M; Cordell G A
Alkyl phenols and derivatives from Tapirira obtusa.
Phytochemistry 2001;56(7):781-4.
2001: Qiu S X; Nguyen V H; Le T X; Gu J Q; Lobkovsky E; Tran C K; Soejarto D D; Clardy J; Pezzuto J M; Dong Y; Mai V T; Le M H; Fong H H
A pregnane steroid from Aglaia lawii and structure confirmation of cabraleadiol monoacetate by X-ray crystallography.
Phytochemistry 2001;56(7):775-80.
2001: Udeani G O; Zhao G M; Shin Y G; Kosmeder J W; Beecher C W; Kinghorn A D; Moriarty R M; Moon R C; Pezzuto J M
Pharmacokinetics of deguelin, a cancer chemopreventive agent in rats.
Cancer chemotherapy and pharmacology 2001;47(3):263-8.
2001: Ito A; Cui B; Chávez D; Chai H B; Shin Y G; Kawanishi K; Kardono L B; Riswan S; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
Cytotoxic polyacetylenes from the twigs of Ochanostachys amentacea.
Journal of natural products 2001;64(2):246-8.
2001: Horgen F D; Edrada R A; de los Reyes G; Agcaoili F; Madulid D A; Wongpanich V; Angerhofer C K; Pezzuto J M; Soejarto D D; Farnsworth N R
Biological screening of rain forest plot trees from Palawan Island (Philippines).
Phytomedicine : international journal of phytotherapy and phytopharmacology 2001;8(1):71-81.
2001: Waffo-Teguo P; Lee D; Cuendet M; Mérillon J; Pezzuto J M; Kinghorn A D
Two new stilbene dimer glucosides from grape (Vitis vinifera) cell cultures.
Journal of natural products 2001;64(1):136-8.
2001: Constantinou A I; Lantvit D; Hawthorne M; Xu X; van Breemen R B; Pezzuto J M
Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats.
Nutrition and cancer 2001;41(1-2):75-81.
2001: Waffo-Téguo P; Hawthorne M E; Cuendet M; Mérillon J M; Kinghorn A D; Pezzuto J M; Mehta R G
Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures.
Nutrition and cancer 2001;40(2):173-9.
2000: Westenburg H E; Lee K J; Lee S K; Fong H H; van Breemen R B; Pezzuto J M; Kinghorn A D
Activity-guided isolation of antioxidative constituents of Cotinus coggygria.
Journal of natural products 2000;63(12):1696-8.
2000: Chang L C; Gills J J; Bhat K P; Luyengi L; Farnsworth N R; Pezzuto J M; Kinghorn A D
Activity-guided isolation of constituents of Cerbera manghas with antiproliferative and antiestrogenic activities.
Bioorganic & medicinal chemistry letters 2000;10(21):2431-4.
2000: Cho K H; Pezzuto J M; Bolton J L; Steele V E; Kelloff G J; Lee S K; Constantinou A
Selection of cancer chemopreventive agents based on inhibition of topoisomerase II activity.
European journal of cancer (Oxford, England : 1990) 2000;36(16):2146-56.
2000: Chang L C; Song L L; Park E J; Luyengi L; Lee K J; Farnsworth N R; Pezzuto J M; Kinghorn A D
Bioactive constituents of Thuja occidentalis.
Journal of natural products 2000;63(9):1235-8.
2000: Qiu S X; Li X C; Xiong Y; Dong Y; Chai H; Fransworth N R; Pezzuto J M; Fong H H
Isolation and characterization of cytotoxic saponin chloromaloside A from Chlorophytum malayense.
Planta medica 2000;66(6):587-90.
2000: Nikolic D; Habibi-Goudarzi S; Corley D G; Gafner S; Pezzuto J M; van Breemen R B
Evaluation of cyclooxygenase-2 inhibitors using pulsed ultrafiltration mass spectrometry.
Analytical chemistry 2000;72(16):3853-9.
2000: Jeong H J; Chang L C; Kim H K; Kim I H; Kinghorn A D; Pezzuto J M
Aromatase inhibitors from Isodon excisus var. coreanus.
Archives of pharmacal research 2000;23(3):243-5.
2000: Peraza-Sánchez S R; Chávez D; Chai H B; Shin Y G; García R; Mejía M; Fairchild C R; Lane K E; Menendez A T; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
Cytotoxic constituents of the roots of Ekmanianthe longiflora.
Journal of natural products 2000;63(4):492-5.
2000: Seo E K; Chai H B; Chagwedera T E; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
5-(4-Hydroxyphenethenyl)-4,7-dimethoxycoumarin, a new constituent of Monotes engleri.
Planta medica 2000;66(2):182-4.
2000: Adeniyi B A; Fong H H; Pezzuto J M; Luyengi L; Odelola H A
Antibacterial activity of diospyrin, isodiospyrin and bisisodiospyrin from the root of Diospyros piscatoria (Gurke) (Ebenaceae).
Phytotherapy research : PTR 2000;14(2):112-7.
2000: Chang L C; Chávez D; Song L L; Farnsworth N R; Pezzuto J M; Kinghorn A D
Absolute configuration of novel bioactive flavonoids from Tephrosia purpurea.
Organic letters 2000;2(4):515-8.
2000: Cuendet M; Pezzuto J M
The role of cyclooxygenase and lipoxygenase in cancer chemoprevention.
Drug metabolism and drug interactions 2000;17(1-4):109-57.
1999: Lee S K; Pezzuto J M
Evaluation of the potential of cancer chemopreventive activity mediated by inhibition of 12-O-tetradecanoyl phorbol 13-acetate-induced ornithine decarboxylase activity.
Archives of pharmacal research 1999;22(6):559-64.
1999: Udeani G O; Zhao G M; Geun Shin Y; Cooke B P; Graham J; Beecher C W; Kinghorn A D; Pezzuto J M
Pharmacokinetics and tissue distribution of betulinic acid in CD-1 mice.
Biopharmaceutics & drug disposition 1999;20(8):379-83.
1999: Cui B; Lee Y H; Chai H; Tucker J C; Fairchild C R; Raventos-Suarez C; Long B; Lane K E; Menendez A T; Beecher C W; Cordell G A; Pezzuto J M; Kinghorn A D
Cytotoxic sesquiterpenoids from Ratibida columnifera.
Journal of natural products 1999;62(11):1545-50.
1999: Shin Y G; Cho K H; Chung S M; Graham J; Das Gupta T K; Pezzuto J M
Determination of betulinic acid in mouse blood, tumor and tissue homogenates by liquid chromatography-electrospray mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications 1999;732(2):331-6.
1999: Ito A; Lee Y H; Chai H B; Gupta M P; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
1',2',3',4'-tetradehydrotubulosine, a cytotoxic alkaloid from Pogonopus speciosus.
Journal of natural products 1999;62(9):1346-8.
1999: Cui B; Chai H; Dong Y; Horgen F D; Hansen B; Madulid D A; Soejarto D D; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
Quinoline alkaloids from Acronychia laurifolia.
Phytochemistry 1999;52(1):95-8.
1999: Jeong H J; Shin Y G; Kim I H; Pezzuto J M
Inhibition of aromatase activity by flavonoids.
Archives of pharmacal research 1999;22(3):309-12.
1999: Topçu G; Erenler R; Cakmak O; Johansson C B; Celik C; Chai H B; Pezzuto J M
Diterpenes from the berries of Juniperus excelsa.
Phytochemistry 1999;50(7):1195-9.
1999: Lin L Z; Hu S F; Chu M; Chan T M; Chai H; Angerhofer C K; Pezzuto J M; Cordell G A
Phenolic aporphine-benzylisoquinoline alkaloids from Thalictrum faberi.
Phytochemistry 1999;50(5):829-34.
1999: Lee S K; Luyengi L; Gerhäuser C; Mar W; Lee K; Mehta R G; Kinghorn A D; Pezzuto J M
Inhibitory effect of munetone, an isoflavonoid, on 12-O-tetradecanoylphorbol 13-acetate-induced ornithine decarboxylase activity.
Cancer letters 1999;136(1):59-65.
1999: Song L L; Kosmeder J W; Lee S K; Gerhäuser C; Lantvit D; Moon R C; Moriarty R M; Pezzuto J M
Cancer chemopreventive activity mediated by 4'-bromoflavone, a potent inducer of phase II detoxification enzymes.
Cancer research 1999;59(3):578-85.
1999: Chung H S; Chang L C; Lee S K; Shamon L A; van Breemen R B; Mehta R G; Farnsworth N R; Pezzuto J M; Kinghorn A D
Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity.
Journal of agricultural and food chemistry 1999;47(1):36-41.
1999: Lee S K; Song L; Mata-Greenwood E; Kelloff G J; Steele V E; Pezzuto J M
Modulation of in vitro biomarkers of the carcinogenic process by chemopreventive agents.
Anticancer research 1999;19(1A):35-44.
1999: Angerhofer C K; Guinaudeau H; Wongpanich V; Pezzuto J M; Cordell G A
Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids.
Journal of natural products 1999;62(1):59-66.
1999: Jang M; Pezzuto J M
Cancer chemopreventive activity of resveratrol.
Drugs under experimental and clinical research 1999;25(2-3):65-77.
1998: Yoosook C; Reutrakul V; Santisuk T; Chaichana S; Pezzuto J M; Dong Y; Clanton D J; Kiser R; Staley P
A sensitive assay for anti-HIV-1 drug discovery in a biological safety level-2 laboratory.
The Southeast Asian journal of tropical medicine and public health 1998;29(4):758-62.
1998: Jang M; Pezzuto J M
Effects of resveratrol on 12-O-tetradecanoylphorbol-13-acetate-induced oxidative events and gene expression in mouse skin.
Cancer letters 1998;134(1):81-9.
1998: Qiu S X; Sun H D; Lobkovsky E; Chai H; Clardy J; Farnsworth N R; Pezzuto J M; Fong H H
Megathyrin B: a cytotoxic diterpene from Isodon megathyrsus.
Planta medica 1998;64(8):728-31.
1998: Cui B; Chai H; Santisuk T; Reutrakul V; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
Novel cytotoxic acylated oligorhamnosides from Mezzettia leptopoda.
Journal of natural products 1998;61(12):1535-8.
1998: Lee S K; Cui B; Mehta R R; Kinghorn A D; Pezzuto J M
Cytostatic mechanism and antitumor potential of novel 1H-cyclopenta[b]benzofuran lignans isolated from Aglaia elliptica.
Chemico-biological interactions 1998;115(3):215-28.
1998: Chang L C; Bhat K P; Pisha E; Kennelly E J; Fong H H; Pezzuto J M; Kinghorn A D
Activity-guided isolation of steroidal alkaloid antiestrogen-binding site inhibitors from Pachysandra procumbens.
Journal of natural products 1998;61(10):1257-62.
1998: Kim D S; Pezzuto J M; Pisha E
Synthesis of betulinic acid derivatives with activity against human melanoma.
Bioorganic & medicinal chemistry letters 1998;8(13):1707-12.
1998: Lee S K; Qing W G; Mar W; Luyengi L; Mehta R G; Kawanishi K; Fong H H; Beecher C W; Kinghorn A D; Pezzuto J M
Angoline and chelerythrine, benzophenanthridine alkaloids that do not inhibit protein kinase C.
The Journal of biological chemistry 1998;273(31):19829-33.
1998: Gamez E J; Luyengi L; Lee S K; Zhu L F; Zhou B N; Fong H H; Pezzuto J M; Kinghorn A D
Antioxidant flavonoid glycosides from Daphniphyllum calycinum.
Journal of natural products 1998;61(5):706-8.
1998: Lee S K; Mbwambo Z H; Chung H; Luyengi L; Gamez E J; Mehta R G; Kinghorn A D; Pezzuto J M
Evaluation of the antioxidant potential of natural products.
Combinatorial chemistry & high throughput screening 1998;1(1):35-46.
1998: Poobrasert O; Constant H L; Beecher C W; Farnsworth N R; Kinghorn A D; Pezzuto J M; Cordell G A; Santisuk T; Reutrakul V
Xanthones from the twigs of Mammea siamensis.
Phytochemistry 1998;47(8):1661-3.
1998: Cui B; Chai H; Constant H L; Santisuk T; Reutrakul V; Beecher C W; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
Limonoids from Azadirachta excelsa.
Phytochemistry 1998;47(7):1283-7.
1998: David J M; Chávez J P; Chai H B; Pezzuto J M; Cordell G A
Two new cytotoxic compounds from Tapirira guianensis.
Journal of natural products 1998;61(2):287-9.
1997: Arda N; Gören N; Kuru A; Pengsuparp T; Pezzuto J M; Qiu S X; Cordell G A
Saniculoside N from Sanicula europaea L.
Journal of natural products 1997;60(11):1170-3.
1997: Schmidt M L; Kuzmanoff K L; Ling-Indeck L; Pezzuto J M
Betulinic acid induces apoptosis in human neuroblastoma cell lines.
European journal of cancer (Oxford, England : 1990) 1997;33(12):2007-10.
1997: Bolton J L; Pisha E; Shen L; Krol E S; Iverson S L; Huang Z; van Breemen R B; Pezzuto J M
The reactivity of o-quinones which do not isomerize to quinone methides correlates with alkylcatechol-induced toxicity in human melanoma cells.
Chemico-biological interactions 1997;106(2):133-48.
1997: Chang L C; Gerhäuser C; Song L; Farnsworth N R; Pezzuto J M; Kinghorn A D
Activity-guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase.
Journal of natural products 1997;60(9):869-73.
1997: Gerhauser C; Lee S K; Kosmeder J W; Moriarty R M; Hamel E; Mehta R G; Moon R C; Pezzuto J M
Regulation of ornithine decarboxylase induction by deguelin, a natural product cancer chemopreventive agent.
Cancer research 1997;57(16):3429-35.
1997: Udeani G O; Gerhauser C; Thomas C F; Moon R C; Kosmeder J W; Kinghorn A D; Moriarty R M; Pezzuto J M
Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid.
Cancer research 1997;57(16):3424-8.
1997: Seo E K; Silva G L; Chai H B; Chagwedera T E; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
Cytotoxic prenylated flavanones from Monotes engleri.
Phytochemistry 1997;45(3):509-15.
1997: Horgen F D; Guinaudeau H; Pezzuto J M; Soejarto D D; Farnsworth N R; Agcaoili F; de los Reyes G; Edrada R A
Isolation and structure elucidation of ardisenone: a new, cytotoxic alkenylphenol from Ardisia iwahigensis.
Journal of natural products 1997;60(5):533-5.
1997: Shen L; Pisha E; Huang Z; Pezzuto J M; Krol E; Alam Z; van Breemen R B; Bolton J L
Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity.
Carcinogenesis 1997;18(5):1093-101.
1997: MacKinnon S; Durst T; Arnason J T; Angerhofer C; Pezzuto J; Sanchez-Vindas P E; Poveda L J; Gbeassor M
Antimalarial activity of tropical Meliaceae extracts and gedunin derivatives.
Journal of natural products 1997;60(4):336-41.
1997: Shamon L A; Pezzuto J M; Graves J M; Mehta R R; Wangcharoentrakul S; Sangsuwan R; Chaichana S; Tuchinda P; Cleason P; Reutrakul V
Evaluation of the mutagenic, cytotoxic, and antitumor potential of triptolide, a highly oxygenated diterpene isolated from Tripterygium wilfordii.
Cancer letters 1997;112(1):113-7.
1997: Gerhäuser C; You M; Liu J; Moriarty R M; Hawthorne M; Mehta R G; Moon R C; Pezzuto J M
Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes.
Cancer research 1997;57(2):272-8.
1997: Jang M; Cai L; Udeani G O; Slowing K V; Thomas C F; Beecher C W; Fong H H; Farnsworth N R; Kinghorn A D; Mehta R G; Moon R C; Pezzuto J M
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes.
Science (New York, N.Y.) 1997;275(5297):218-20.
1996: Mbwambo Z H; Lee S K; Mshiu E N; Pezzuto J M; Kinghorn A D
Constituents from the stem wood of Euphorbia quinquecostata with phorbol dibutyrate receptor-binding inhibitory activity.
Journal of natural products 1996;59(11):1051-5.
1996: Pengsuparp T; Serit M; Hughes S H; Soejarto D D; Pezzuto J M
Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of calophyllum teysmannii.
Journal of natural products 1996;59(9):839-42.
1996: Luyengi L; Suh N; Fong H H; Pezzuto J M; Kinghorn A D
A lignan and four terpenoids from Brucea javanica that induce differentiation with cultured HL-60 promyelocytic leukemia cells.
Phytochemistry 1996;43(2):409-12.
1996: Pengsuparp T; Kingston D G; Neidigh K A; Cordell G A; Pezzuto J M
Evaluation of the cytotoxic mechanism mediated by baccatin III, the synthetic precursor of taxol.
Chemico-biological interactions 1996;101(2):103-14.
1996: Sturm S; Gil R R; Chai H B; Ngassapa O D; Santisuk T; Reutrakul V; Howe A; Moss M; Besterman J M; Yang S L; Farthing J E; Tait R M; Lewis J A; O'Neill M J; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
Lupane derivatives from Lophopetalum wallichii with farnesyl protein transferase inhibitory activity.
Journal of natural products 1996;59(7):658-63.
1996: Sun H D; Qiu S X; Lin L Z; Wang Z Y; Lin Z W; Pengsuparp T; Pezzuto J M; Fong H H; Cordell G A; Farnsworth N R
Nigranoic acid, a triterpenoid from Schisandra sphaerandra that inhibits HIV-1 reverse transcriptase.
Journal of natural products 1996;59(5):525-7.
1996: Oksüz S; Gürek F; Lin L Z; Gil R R; Pezzuto J M; Cordell G A
Aleppicatines A and B from Euphorbia aleppica.
Phytochemistry 1996;42(2):473-8.
1996: Huang L; Fullas F; McGivney R J; Brown D M; Wani M C; Wall M E; Tucker J C; Beecher C W; Pezzuto J M; Kinghorn A D
A new prenylated flavonol from the root of Petalostemon purpureus.
Journal of natural products 1996;59(3):290-2.
1996: Tan G T; Lee S; Lee I S; Chen J; Leitner P; Besterman J M; Kinghorn A D; Pezzuto J M
Natural-product inhibitors of human DNA ligase I.
The Biochemical journal 1996;314 ( Pt 3)():993-1000.
1996: Lee I S; Shamon L A; Chai H B; Chagwedera T E; Besterman J M; Farnsworth N R; Cordell G A; Pezzuto J M; Kinghorn A D
Cell-cycle specific cytotoxicity mediated by rearranged ent-kaurene diterpenoids isolated from Parinari curatellifolia.
Chemico-biological interactions 1996;99(1-3):193-204.
1995: Leaman D J; Arnason J T; Yusuf R; Sangat-Roemantyo H; Soedjito H; Angerhofer C K; Pezzuto J M
Malaria remedies of the Kenyah of the Apo Kayan, East Kalimantan, Indonesian Borneo: a quantitative assessment of local consensus as an indicator of biological efficacy.
Journal of ethnopharmacology 1995;49(1):1-16.
1995: Lin L Z; Hu S F; Chai H B; Pengsuparp T; Pezzuto J M; Cordell G A; Ruangrungsi N
Lycorine alkaloids from Hymenocallis littoralis.
Phytochemistry 1995;40(4):1295-8.
1995: Fullas F; Brown D M; Wani M C; Wall M E; Chagwedera T E; Farnsworth N R; Pezzuto J M; Kinghorn A D
Gummiferol, a cytotoxic polyacetylene from the leaves of Adenia gummifera.
Journal of natural products 1995;58(10):1625-8.
1995: Silva G L; Chai H; Gupta M P; Farnsworth N R; Cordell G A; Pezzuto J M; Beecher C W; Kinghorn A D
Cytotoxic biflavonoids from Selaginella willdenowii.
Phytochemistry 1995;40(1):129-34.
1995: Falch B S; König G M; Wright A D; Sticher O; Angerhofer C K; Pezzuto J M; Bachmann H
Biological activities of cyanobacteria: evaluation of extracts and pure compounds.
Planta medica 1995;61(4):321-8.
1995: Pengsuparp T; Cai L; Constant H; Fong H H; Lin L Z; Kinghorn A D; Pezzuto J M; Cordell G A; Ingolfsdóttir K; Wagner H
Mechanistic evaluation of new plant-derived compounds that inhibit HIV-1 reverse transcriptase.
Journal of natural products 1995;58(7):1024-31.
1995: Gil R R; Lin L Z; Chai H B; Pezzuto J M; Cordell G A
Cardenolides from Nierembergia aristata.
Journal of natural products 1995;58(6):848-56.
1995: You M; Wickramaratne D B; Silva G L; Chai H; Chagwedera T E; Farnsworth N R; Cordell G A; Kinghorn A D; Pezzuto J M
(-)-Roemerine, an aporphine alkaloid from Annona senegalensis that reverses the multidrug-resistance phenotype with cultured cells.
Journal of natural products 1995;58(4):598-604.
1995: Oksüz S; Gürek F; Gil R R; Pengsuparp T; Pezzuto J M; Cordell G A
Four diterpene esters from Euphorbia myrsinites.
Phytochemistry 1995;38(6):1457-62.
1995: Suh N; Luyengi L; Fong H H; Kinghorn A D; Pezzuto J M
Discovery of natural product chemopreventive agents utilizing HL-60 cell differentiation as a model.
Anticancer research 1995;15(2):233-9.
1995: Mehta R G; Liu J; Constantinou A; Thomas C F; Hawthorne M; You M; Gerhüser C; Pezzuto J M; Moon R C; Moriarty R M
Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage.
Carcinogenesis 1995;16(2):399-404.
1995: Wickramaratne D B; Mar W; Chai H; Castillo J J; Farnsworth N R; Soejarto D D; Cordell G A; Pezzuto J M; Kinghorn A D
Cytotoxic constituents of Bursera permollis.
Planta medica 1995;61(1):80-1.
1995: Sun H D; Lin Z W; Niu F D; Lin L Z; Chai H B; Pezzuto J M; Cordell G A
Cytotoxic ent-kaurene diterpenoids from three Isodon species.
Phytochemistry 1995;38(2):437-42.
1994: Oksüz S; Gil R R; Chai H; Pezzuto J M; Cordell G A; Ulubelen A
Biologically active compounds from the Euphorbiaceae; 2. Two triterpenoids of Euphorbia cyparissias.
Planta medica 1994;60(6):594-6.
1994: König G M; Wright A D; Sticher O; Angerhofer C K; Pezzuto J M
Biological activities of selected marine natural products.
Planta medica 1994;60(6):532-7.
1994: Ma X; Lee I S; Chai H B; Zaw K; Farnsworth N R; Soejarto D D; Cordell G A; Pezzuto J M; Kinghorn A D
Cytotoxic clerodane diterpenes from Polyalthia barnesii.
Phytochemistry 1994;37(6):1659-62.
1994: You M; Ma X; Mukherjee R; Farnsworth N R; Cordell G A; Kinghorn A D; Pezzuto J M
Indole alkaloids from Peschiera laeta that enhance vinblastine-mediated cytotoxicity with multidrug-resistant cells.
Journal of natural products 1994;57(11):1517-22.
1994: Lin L Z; Hu S F; Zaw K; Angerhofer C K; Chai H; Pezzuto J M; Cordell G A; Lin J; Zheng D M
Thalifaberidine, a cytotoxic aporphine-benzylisoquinoline alkaloid from Thalictrum faberi.
Journal of natural products 1994;57(10):1430-6.
1994: Sun H D; Lin Z W; Niu F D; Lin L Z; Chai H; Pezzuto J M; Cordell G A
Cytotoxic diterpenoids from Isodon megathyrsus.
Journal of natural products 1994;57(10):1424-9.
1994: Shamon L A; Chen C; Mehta R G; Steele V; Moon R C; Pezzuto J M
A correlative approach for the identification of antimutagens that demonstrate chemopreventive activity.
Anticancer research 1994;14(5A):1775-8.
1994: Rimando A M; Pezzuto J M; Farnsworth N R; Santisuk T; Reutrakul V; Kawanishi K
New lignans from Anogeissus acuminata with HIV-1 reverse transcriptase inhibitory activity.
Journal of natural products 1994;57(7):896-904.
1994: Fullas F; Hussain R A; Chai H B; Pezzuto J M; Soejarto D D; Kinghorn A D
Cytotoxic constituents of Baccharis gaudichaudiana.
Journal of natural products 1994;57(6):801-7.
1994: Wall M E; Wani M C; Fullas F; Oswald J B; Brown D M; Santisuk T; Reutrakul V; McPhail A T; Farnsworth N R; Pezzuto J M
Plant antitumor agents. 31. The calycopterones, a new class of biflavonoids with novel cytotoxicity in a diverse panel of human tumor cell lines.
Journal of medicinal chemistry 1994;37(10):1465-70.
1994: Mehta R G; Liu J; Constantinou A; Hawthorne M; Pezzuto J M; Moon R C; Moriarty R M
Structure-activity relationships of brassinin in preventing the development of carcinogen-induced mammary lesions in organ culture.
Anticancer research 1994;14(3A):1209-13.
1994: Pengsuparp T; Cai L; Fong H H; Kinghorn A D; Pezzuto J M; Wani M C; Wall M E
Pentacyclic triterpenes derived from Maprounea africana are potent inhibitors of HIV-1 reverse transcriptase.
Journal of natural products 1994;57(3):415-8.
1994: Ngassapa O; Soejarto D D; Pezzuto J M; Farnsworth N R
Quinone-methide triterpenes and salaspermic acid from Kokoona ochracea.
Journal of natural products 1994;57(1):1-8.
1993: Wickramaratne D B; Pengsuparp T; Mar W; Chai H B; Chagwedera T E; Beecher C W; Farnsworth N R; Kinghorn A D; Pezzuto J M; Cordell G A
Novel antimitotic dibenzocyclo-octadiene lignan constituents of the stem bark of Steganotaenia araliacea.
Journal of natural products 1993;56(12):2083-90.
1993: Luyengi L; Pezzuto J M; Waller D P; Beecher C W; Fong H H; Che C T; Bowen P E
Linusitamarin, a new phenylpropanoid glucoside from Linum usitatissimum.
Journal of natural products 1993;56(11):2012-5.
1993: Ngassapa O; Beecher C W; Pezzuto J M; Farnsworth N R; Henderson T O; Boye G L
Isolation of echinocystic acid-3-O-sulfate, a new triterpene, from Tetrapleura tetraptera, and evaluation of the mutagenic potential of molluscicidal extracts and isolates.
Journal of natural products 1993;56(11):1872-7.
1993: Novelo M; Cruz J G; Hernández L; Pereda-Miranda R; Chai H; Mar W; Pezzuto J M
Cytotoxic constituents from Hyptis verticillata.
Journal of natural products 1993;56(10):1728-36.
1993: Ngassapa O; Soejarto D D; Pezzuto J M; Farnsworth N R; Che C T
Further lupane lactones from Kokoona ochracea.
Journal of natural products 1993;56(10):1676-81.
1993: Baek N I; Chung M S; Shamon L; Kardono L B; Tsauri S; Padmawinata K; Pezzuto J M; Soejarto D D; Kinghorn A D
Selligueain A, a novel highly sweet proanthocyanidin from the rhizomes of Selliguea feei.
Journal of natural products 1993;56(9):1532-8.
1993: Likhitwitayawuid K; Angerhofer C K; Chai H; Pezzuto J M; Cordell G A; Ruangrungsi N
Cytotoxic and antimalarial alkaloids from the tubers of Stephania pierrei.
Journal of natural products 1993;56(9):1468-78.
1993: Likhitwitayawuid K; Angerhofer C K; Chai H; Pezzuto J M; Cordell G A; Ruangrungsi N
Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
Journal of natural products 1993;56(8):1331-8.
1993: Pereda-Miranda R; Hernández L; Villavicencio M J; Novelo M; Ibarra P; Chai H; Pezzuto J M
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
Journal of natural products 1993;56(4):583-93.
1993: Pereda-Miranda R; Mata R; Anaya A L; Wickramaratne D B; Pezzuto J M; Kinghorn A D
Tricolorin A, major phytogrowth inhibitor from Ipomoea tricolor.
Journal of natural products 1993;56(4):571-82.
1993: Saifah E; Puripattanavong J; Likhitwitayawuid K; Cordell G A; Chai H; Pezzuto J M
Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
Journal of natural products 1993;56(4):473-7.
1993: Tan G T; Wickramasinghe A; Verma S; Hughes S H; Pezzuto J M; Baba M; Mohan P
Sulfonic acid polymers are potent inhibitors of HIV-1 induced cytopathogenicity and the reverse transcriptases of both HIV-1 and HIV-2.
Biochimica et biophysica acta 1993;1181(2):183-8.
1993: Somanabandhu A; Nitayangkura S; Mahidol C; Ruchirawat S; Likhitwitayawuid K; Shieh H L; Chai H; Pezzuto J M; Cordell G A
1H- and 13C-nmr assignments of phyllanthin and hypophyllanthin: lignans that enhance cytotoxic responses with cultured multidrug-resistant cells.
Journal of natural products 1993;56(2):233-9.
1993: Likhitwitayawuid K; Angerhofer C K; Cordell G A; Pezzuto J M; Ruangrungsi N
Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Stephania erecta.
Journal of natural products 1993;56(1):30-8.
1993: Lin L Z; Shieh H L; Angerhofer C K; Pezzuto J M; Cordell G A; Xue L; Johnson M E; Ruangrungsi N
Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Cyclea barbata.
Journal of natural products 1993;56(1):22-9.
1992: Angerhofer C K; Pezzuto J M; König G M; Wright A D; Sticher O
Antimalarial activity of sesquiterpenes from the marine sponge Acanthella klethra.
Journal of natural products 1992;55(12):1787-9.
1992: Tan G T; Wickramasinghe A; Verma S; Singh R; Hughes S H; Pezzuto J M; Baba M; Mohan P
Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities.
Journal of medicinal chemistry 1992;35(26):4846-53.
1992: Kaneda N; Chai H; Pezzuto J M; Kinghorn A D; Farnsworth N R; Tuchinda P; Udchachon J; Santisuk T; Reutrakul V
Cytotoxic activity of cardenolides from Beaumontia brevituba stems.
Planta medica 1992;58(5):429-31.
1992: Kaneda N; Pezzuto J M; Kinghorn A D; Farnsworth N R; Santisuk T; Tuchinda P; Udchachon J; Reutrakul V
Plant anticancer agents, L. cytotoxic triterpenes from Sandoricum koetjape stems.
Journal of natural products 1992;55(5):654-9.
1992: Tan G T; Miller J F; Kinghorn A D; Hughes S H; Pezzuto J M
HIV-1 and HIV-2 reverse transcriptases: a comparative study of sensitivity to inhibition by selected natural products.
Biochemical and biophysical research communications 1992;185(1):370-8.
1992: Shieh H L; Pezzuto J M; Cordell G A
Evaluation of the cytotoxic mechanisms mediated by the broad-spectrum antitumor alkaloid acronycine and selected semisynthetic derivatives.
Chemico-biological interactions 1992;81(1-2):35-55.
1991: Zong Y; Lowell K; Ping J A; Che C T; Pezzuto J M; Fong H H
Phenolic constituents of Rhodiola coccinea, a Tibetan folk medicine.
Planta medica 1991;57(6):589.
1991: Tan G T; Kinghorn A D; Hughes S H; Pezzuto J M
Psychotrine and its O-methyl ether are selective inhibitors of human immunodeficiency virus-1 reverse transcriptase.
The Journal of biological chemistry 1991;266(35):23529-36.
1991: Pezzuto J M; Che C T; McPherson D D; Zhu J P; Topcu G; Erdelmeier C A; Cordell G A
DNA as an affinity probe useful in the detection and isolation of biologically active natural products.
Journal of natural products 1991;54(6):1522-30.
1991: Mar W; Tan G T; Cordell G A; Pezzuto J M; Jurcic K; Offermann F; Redl K; Steinke B; Wagner H
Biological activity of novel macrocyclic alkaloids (budmunchiamines) from Albizia amara detected on the basis of interaction with DNA.
Journal of natural products 1991;54(6):1531-42.
1991: Kardono L B; Angerhofer C K; Tsauri S; Padmawinata K; Pezzuto J M; Kinghorn A D
Cytotoxic and antimalarial constituents of the roots of Eurycoma longifolia.
Journal of natural products 1991;54(5):1360-7.
1991: Ngassapa O D; Soejarto D D; Che C T; Pezzuto J M; Farnsworth N R
New cytotoxic lupane lactones from Kokoona ochracea.
Journal of natural products 1991;54(5):1353-9.
1991: Cordell G A; Beecher C W; Pezzuto J M
Can ethnopharmacology contribute to the development of new anticancer drugs?
Journal of ethnopharmacology 1991;32(1-3):117-33.
1991: Kaneda N; Pezzuto J M; Soejarto D D; Kinghorn A D; Farnsworth N R; Santisuk T; Tuchinda P; Udchachon J; Reutrakul V
Plant anticancer agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots.
Journal of natural products 1991;54(1):196-206.
1991: Tan G T; Pezzuto J M; Kinghorn A D; Hughes S H
Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
Journal of natural products 1991;54(1):143-54.
1991: Duh C Y; Kinghorn A D; Pezzuto J M
Cell-cycle specific cytotoxicity mediated by stizophyllin (2 alpha,3 beta,12 beta-trihydroxypregna-4,7,16-trien-20-one), a novel electrophilic pregnane isolated from Stizophyllum riparium.
Chemico-biological interactions 1991;80(1):43-56.
1990: Kardono L B; Tsauri S; Padmawinata K; Pezzuto J M; Kinghorn A D
Cytotoxic constituents of the bark of Plumeria rubra collected in Indonesia.
Journal of natural products 1990;53(6):1447-55.
1990: Bavovada R; Blaskó G; Shieh H L; Pezzuto J M; Cordell G A
Spectral assignment and cytotoxicity of 22-hydroxytingenone from Glyptopetalum sclerocarpum.
Planta medica 1990;56(4):380-2.
1990: Hussain R A; Lin Y M; Poveda L J; Bordas E; Chung B S; Pezzuto J M; Soejarto D D; Kinghorn A D
Plant-derived sweetening agents: saccharide and polyol constituents of some sweet-tasting plants.
Journal of ethnopharmacology 1990;28(1):103-15.
1989: Braun R J; Pezzuto J M; Anderson C H; Beattie C W
Estrous cycle status alters N-methyl-N-nitrosourea (NMU)-induced rat mammary tumor growth and regression.
Cancer letters 1989;48(3):205-11.
1989: Kigodi P G; Blaskó G; Thebtaranonth Y; Pezzuto J M; Cordell G A
Spectroscopic and biological investigation of nimbolide and 28-deoxonimbolide from Azadirachta indica.
Journal of natural products 1989;52(6):1246-51.
1989: Choi Y H; Hussain R A; Pezzuto J M; Kinghorn A D; Morton J F
Abrusosides A-D, four novel sweet-tasting triterpene glycosides from the leaves of Abrus precatorius.
Journal of natural products 1989;52(5):1118-27.
1989: Jonathan L T; Che C T; Pezzuto J M; Fong H H; Farnsworth N R
7-O-methylhorminone and other cytotoxic diterpene quinones from Lepechinia bullata.
Journal of natural products 1989;52(3):571-5.
1988: Pezzuto J M; Shieh H L; Shaughnessy E; Beattie C W
Approaches for drug development in treatment of advanced melanoma.
Seminars in oncology 1988;15(6):578-88.
1988: Pezzuto J M; Swanson S M; Mar W; Che C T; Cordell G A; Fong H H
Evaluation of the mutagenic and cytostatic potential of aristolochic acid (3,4-methylenedioxy-8-methoxy-10-nitrophenanthrene-1-carboxylic acid) and several of its derivatives.
Mutation research 1988;206(4):447-54.
1988: Kim J; Pezzuto J M; Soejarto D D; Lang F A; Kinghorn A D
Polypodoside A, an intensely sweet constituent of the rhizomes of Polypodium glycyrrhiza.
Journal of natural products 1988;51(6):1166-72.
1988: Swanson S M; Jiang J X; Chang Y S; De Souza N J; Pezzuto J M
A rapid and sensitive bioassay involving cultured rat glioma cells to screen for substances capable of elevating intracellular cyclic AMP concentration.
Journal of natural products 1988;51(5):929-36.
1988: Nanayakkara N P; Hussain R A; Pezzuto J M; Soejarto D D; Kinghorn A D
An intensely sweet dihydroflavonol derivative based on a natural product lead compound.
Journal of medicinal chemistry 1988;31(6):1250-3.
1988: Ratko T A; Braun R J; Pezzuto J M; Beattie C W
Estrous cycle modification of rat mammary gland DNA alkylation by N-methyl-N-nitrosourea.
Cancer research 1988;48(11):3090-3.
1988: Lam L K; Garg P K; Swanson S M; Pezzuto J M
Evaluation of the cytotoxic potential of catechols and quinones structurally related to butylated hydroxyanisole.
Journal of pharmaceutical sciences 1988;77(5):393-5.
1988: Liu S Q; Pezzuto J M; Kinghorn A D; Scheld H W
Additional biologically active constituents of the Chinese tallow tree (Sapium sebiferum).
Journal of natural products 1988;51(3):619-20.
1988: Compadre C M; Hussain R A; Lopez de Compadre R L; Pezzuto J M; Kinghorn A D
Analysis of structural features responsible for the sweetness of the sesquiterpene, hernandulcin.
Experientia 1988;44(5):447-9.
1988: Compadre C M; Hussain R A; Nanayakkara N P; Pezzuto J M; Kinghorn A D
Mass spectral analysis of some derivatives and in vitro metabolites of steviol, the aglycone of the natural sweeteners, stevioside, rebaudioside A, and rubusoside.
Biomedical & environmental mass spectrometry 1988;15(4):211-22.
1988: Choi Y H; Pezzuto J M; Kinghorn A D; Farnsworth N R
Plant anticancer agents, XLVI. Cytotoxic casbane-type constituents of Agrostistachys hookeri.
Journal of natural products 1988;51(1):110-6.
1987: Braun R J; Ratko T A; Pezzuto J M; Beattie C W
Estrous cycle modification of rat uterine DNA alkylation by N-methyl-N-nitrosourea.
Cancer letters 1987;37(3):345-52.
1987: Nanayakkara N P; Klocke J A; Compadre C M; Hussain R A; Pezzuto J M; Kinghorn A D
Characterization and feeding deterrent effects on the aphid, Schizaphis graminum, of some derivatives of the sweet compounds, stevioside and rebaudioside A.
Journal of natural products 1987;50(3):434-41.
1987: Wong S M; Konno C; Oshima Y; Pezzuto J M; Fong H H; Farnsworth N R
Irisones A and B: two new isoflavones from Iris missouriensis.
Journal of natural products 1987;50(2):178-80.
1986: Wong S M; Pezzuto J M; Fong H H; Farnsworth N R
Isolation and characterization of a new triterpene from Iris missouriensis.
Journal of natural products 1986;49(2):330-3.
1986: Wong S M; Oshima Y; Pezzuto J M; Fong H H; Farnsworth N R
Plant anticancer agents XXXIX: Triterpenes from Iris missouriensis (Iridaceae).
Journal of pharmaceutical sciences 1986;75(3):317-20.
1986: Pezzuto J M; Nanayakkara N P; Compadre C M; Swanson S M; Kinghorn A D; Guenthner T M; Sparnins V L; Lam L K
Characterization of bacterial mutagenicity mediated by 13-hydroxy-ent-kaurenoic acid (steviol) and several structurally-related derivatives and evaluation of potential to induce glutathione S-transferase in mice.
Mutation research 1986;169(3):93-103.
1985: Wong S M; Pezzuto J M; Fong H H; Farnsworth N R
Isolation, structural elucidation, and chemical synthesis of 2-hydroxy-3-octadecyl-5-methoxy-1,4-benzoquinone (irisoquin), a cytotoxic constituent of Iris missouriensis.
Journal of pharmaceutical sciences 1985;74(10):1114-6.
1985: Pezzuto J M; Compadre C M; Swanson S M; Nanayakkara D; Kinghorn A D
Metabolically activated steviol, the aglycone of stevioside, is mutagenic.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(8):2478-82.
1985: Compadre C M; Pezzuto J M; Kinghorn A D; Kamath S K
Hernandulcin: an intensely sweet compound discovered by review of ancient literature.
Science (New York, N.Y.) 1985;227(4685):417-9.
1984: Marcelle G B; Ahmed M S; Pezzuto J M; Cordell G A; Waller D P; Soejarto D D; Fong H H
Analysis of gossypol and gossypol-acetic acid by high-performance liquid chromatography.
Journal of pharmaceutical sciences 1984;73(3):396-8.

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