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Klaus Pfeffer

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Daniel Degrandi; Verena Klümpers; Carolin Konermann; Elisabeth Kravets; Sarah Lahme; Anne K Mausberg; Sandra Beer-Hammer; Cornelia Beuter-Gunia; Eva Wischmann; Klaus Pfeffer
Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.
Elisabeth Kravets; Julia M Dargazanli; Daniel Degrandi; Suren Felekyan; Carolin Konermann; Gerrit J K Praefcke; Britta Ries; Lutz Schmitt; Claus A M Seidel; Sander H J Smits; Stefanie Weidtkamp-Peters; Klaus Pfeffer
The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.
Petra Gais; Felicitas Altmayr; Klaus-Peter Janssen; Gabriela Jusek; Klaus Pfeffer; Daniel Reim; Tanja Rossmann-Bloeck; Heike Weighardt; Bernhard Holzmann
Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.

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2013: Daniel Degrandi; Verena Klümpers; Carolin Konermann; Elisabeth Kravets; Sarah Lahme; Anne K Mausberg; Sandra Beer-Hammer; Cornelia Beuter-Gunia; Eva Wischmann; Klaus Pfeffer
Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(1):294-9.
2012: Elisabeth Kravets; Julia M Dargazanli; Daniel Degrandi; Suren Felekyan; Carolin Konermann; Gerrit J K Praefcke; Britta Ries; Lutz Schmitt; Claus A M Seidel; Sander H J Smits; Stefanie Weidtkamp-Peters; Klaus Pfeffer
The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.
The Journal of biological chemistry 2012;287(33):27452-66.
2012: Petra Gais; Felicitas Altmayr; Klaus-Peter Janssen; Gabriela Jusek; Klaus Pfeffer; Daniel Reim; Tanja Rossmann-Bloeck; Heike Weighardt; Bernhard Holzmann
Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(12):5833-7.
2012: Philipp Ellinger; Holger Gohlke; Colin MacKenzie; Santosh Panjikar; Klaus Pfeffer; Lutz Schmitt; Britta Tschapek; Rolf Wagner; Reinhild Wurm; Ümit Pul; Zihni Arslan; Sander H J Smits
The crystal structure of the CRISPR-associated protein Csn2 from Streptococcus agalactiae.
Journal of structural biology 2012;178(3):350-62.
2012: Nadin Wimmer; Nicola Barabas; Barbara Huber; Klaus Pfeffer; Johann Röhrl; Anja K Wege; Thomas Hehlgans
Lymphotoxin-beta receptor activation on macrophages ameliorates acute DSS-induced intestinal inflammation in a TRIM30α-dependent manner.
Molecular immunology 2012;51(2):128-35.
2012: Nadin Wimmer; Nicola Barabas; Barbara Huber; Klaus Pfeffer; Johann Röhrl; Thomas Hehlgans
Lymphotoxin β receptor activation on macrophages induces cross-tolerance to TLR4 and TLR9 ligands.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(7):3426-33.
2011: Sabine Messler; Sonja Kropp; Vasso Episkopou; Angelina Felici; Jan Würthner; Robin Lemke; Moran Jerabek-Willemsen; Regina Willecke; Stefanie Scheu; Klaus Pfeffer; Jens U Wurthner
The TGF-β signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development.
Immunobiology 2011;216(3):343-50.
2010: Sandra Beer-Hammer; Eva Zebedin; Max von Holleben; Judith Alferink; Bernhard Reis; Philipp Dresing; Daniel Degrandi; Stefanie Scheu; Emilio Hirsch; Veronika Sexl; Klaus Pfeffer; Bernd Nürnberg; Roland P Piekorz
The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation.
Journal of leukocyte biology 2010;87(6):1083-95.
2010: Birgit Henrich; Marcus Schmitt; Nora Bergmann; Klaus Zanger; Ralf Kubitz; Dieter Häussinger; Klaus Pfeffer
Mycoplasma salivarium detected in a microbial community with Candida glabrata in the biofilm of an occluded biliary stent.
Journal of medical microbiology 2010;59(Pt 2):239-41.
2010: Christoph Hardegen; Sabine Messler; Birgit Henrich; Klaus Pfeffer; Jens Würthner; Colin R Mackenzie
A set of novel multiplex Taqman real-time PCRs for the detection of diarrhoeagenic Escherichia coli and its use in determining the prevalence of EPEC and EAEC in a university hospital.
Annals of clinical microbiology and antimicrobials 2010;9():5.
2009: Maike Förster; Kai Sievert; Sabine Messler; Sven Klimpel; Klaus Pfeffer
Comprehensive study on the occurrence and distribution of pathogenic microorganisms carried by synanthropic flies caught at different rural locations in Germany.
Journal of medical entomology 2009;46(5):1164-6.
2009: Manfred Kneilling; Reinhard Mailhammer; Lothar Hültner; Tanja Schönberger; Kerstin Fuchs; Martin Schaller; Daniel Bukala; Steffen Massberg; Christian Sander; Heidi Braumüller; Martin Eichner; Konrad L Maier; Rupert Hallmann; Bernd J Pichler; Roland Haubner; Meinrad Gawaz; Klaus Pfeffer; Tilo Biedermann; Martin Röcken
Direct crosstalk between mast cell-TNF and TNFR1-expressing endothelia mediates local tissue inflammation.
Blood 2009;114(8):1696-706.
2009: Yonglian Sun; Nicholas K Brown; Matthew J Ruddy; Mendy L Miller; Youjin Lee; Yang Wang; Kenneth M Murphy; Klaus Pfeffer; Lieping Chen; Jonathan Kaye; Yang-Xin Fu
B and T lymphocyte attenuator tempers early infection immunity.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(3):1946-51.
2009: Mirko Trilling; Vu Thuy Khanh Le; Albert Zimmermann; Holger Ludwig; Klaus Pfeffer; Gerd Sutter; Geoffrey L Smith; Hartmut Hengel
Gamma interferon-induced interferon regulatory factor 1-dependent antiviral response inhibits vaccinia virus replication in mouse but not human fibroblasts.
Journal of virology 2009;83(8):3684-95.
2009: Bernhard Reis; Klaus Pfeffer; Sandra Beer-Hammer
The orphan adapter protein SLY1 as a novel anti-apoptotic protein required for thymocyte development.
BMC immunology 2009;10():38.
2009: Daniel Degrandi; Reinhard Hoffmann; Cornelia Beuter-Gunia; Klaus Pfeffer
The proinflammatory cytokine-induced IRG1 protein associates with mitochondria.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2009;29(1):55-67.
2008: Tobias Traeger; Wolfram Kessler; Volker Assfalg; Katharina Cziupka; Pia Koerner; Constanze Dassow; Katrin Breitbach; Marlene Mikulcak; Ivo Steinmetz; Klaus Pfeffer; Claus-Dieter Heidecke; Stefan Maier
Detrimental role of CC chemokine receptor 4 in murine polymicrobial sepsis.
Infection and immunity 2008;76(11):5285-93.
2008: Stefanie Kutsch; Daniel Degrandi; Klaus Pfeffer
Immediate lymphotoxin beta receptor-mediated transcriptional response in host defense against L. monocytogenes.
Immunobiology 2008;213(3-4):353-66.
2008: Alexandra Kresse; Carolin Konermann; Daniel Degrandi; Cornelia Beuter-Gunia; Jan Wuerthner; Klaus Pfeffer; Sandra Beer
Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies.
BMC genomics 2008;9():158.
2007: Daniel Degrandi; Carolin Konermann; Cornelia Beuter-Gunia; Alexandra Kresse; Jan Würthner; Stefanie Kurig; Sandra Beer; Klaus Pfeffer
Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7729-40.
2007: Carolin Konermann; Alexandra Kresse; Cornelia Beuter-Gunia; Jan Würthner; Daniel Degrandi; Klaus Pfeffer; Sandra Beer
In silico and in vitro characterization of mGBP4 splice variants.
DNA and cell biology 2007;26(12):847-51.
2007: Norman-Philipp Hoff; Daniel Degrandi; Ulrich R Hengge; Klaus Pfeffer; Jens Ulrich Wurthner
Carboxypeptidase D: a novel TGF-beta target gene dysregulated in patients with lupus erythematosus.
Journal of clinical immunology 2007;27(6):568-79.
2007: Bernd Rebholz; Ingo Haase; Birgit Eckelt; Stephan Paxian; Michael J Flaig; Kamran Ghoreschi; Sergei A Nedospasov; Reinhard Mailhammer; Svenja Debey-Pascher; Joachim L Schultze; Günther Weindl; Irmgard Förster; Ralf Huss; Athanasios Stratis; Thomas Ruzicka; Martin Röcken; Klaus Pfeffer; Roland M Schmid; Rudolf A Rupec
Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin.
Immunity 2007;27(2):296-307.
2007: Maike Förster; Sven Klimpel; Heinz Mehlhorn; Kai Sievert; Sabine Messler; Klaus Pfeffer
Pilot study on synanthropic flies (e.g. Musca, Sarcophaga, Calliphora, Fannia, Lucilia, Stomoxys) as vectors of pathogenic microorganisms.
Parasitology research 2007;101(1):243-6.
2007: Stephan Spiller; Stefan Dreher; Guangxun Meng; Alina Grabiec; Winston Thomas; Thomas Hartung; Klaus Pfeffer; Hubertus Hochrein; Helmut Brade; Wolfgang Bessler; Hermann Wagner; Carsten J Kirschning
Cellular recognition of trimyristoylated peptide or enterobacterial lipopolysaccharide via both TLR2 and TLR4.
The Journal of biological chemistry 2007;282(18):13190-8.
2006: Anna Sandqvist; Helen Kalies; Anette Siedler; Britta Gröndahl; Heinz-J. (Joe) Schmitt; Susanne Schweitzer-Krantz; A Martina Messing-Jünger; Klaus Pfeffer; Ertan Mayatepek; Rüdiger von Kries; Horst Schroten
Invasive nontypeable Haemophilus influenzae infections in Germany: a case report of a previously healthy 7-year-old boy with an intracranial abscess, and epidemiological data from 2001 to 2004.
European journal of pediatrics 2006;165(9):658-9.
2006: Ulrich Warskulat; Elena Borsch; Roland Reinehr; Birgit Heller-Stilb; Irmhild Mönnighoff; Darius Buchczyk; Markus G Donner; Ulrich Flögel; Günther Kappert; Sibylle Soboll; Sandra Beer; Klaus Pfeffer; Hanns-Ulrich Marschall; Marcus Gabrielsen; Mahmood Amiry-Moghaddam; Ole Petter Ottersen; Hans P Dienes; Dieter Häussinger
Chronic liver disease is triggered by taurine transporter knockout in the mouse.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(3):574-6.
2006: Markus Entleutner; Tobias Traeger; Alexandra Westerholt; Bernhard Holzmann; Albrecht Stier; Klaus Pfeffer; Stefan Maier; Claus-Dieter Heidecke
Impact of interleukin-12, oxidative burst, and iNOS on the survival of murine fecal peritonitis.
International journal of colorectal disease 2006;21(1):64-70.
2005: Sandra Beer; Tanja Scheikl; Bernhard Reis; Norbert Hüser; Klaus Pfeffer; Bernhard Holzmann
Impaired immune responses and prolonged allograft survival in Sly1 mutant mice.
Molecular and cellular biology 2005;25(21):9646-60.
2005: Marc Riemann; Robert Endres; Susanne Liptay; Klaus Pfeffer; Roland M Schmid
The IkappaB protein Bcl-3 negatively regulates transcription of the IL-10 gene in macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):3560-8.
2005: Regina Klose; Elisabeth Kemter; Tanja Bedke; Iris Bittmann; Barbara Kelsser; Robert Endres; Klaus Pfeffer; Reinhard Schwinzer; Eckhard Wolf
Expression of biologically active human TRAIL in transgenic pigs.
Transplantation 2005;80(2):222-30.
2005: Robert A Anders; Sumit K Subudhi; Jing Wang; Klaus Pfeffer; Yang-Xin Fu
Contribution of the lymphotoxin beta receptor to liver regeneration.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):1295-300.
2005: Jing Wang; Robert A Anders; Yang Wang; Jerrold R Turner; Clara Abraham; Klaus Pfeffer; Yang-Xin Fu
The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):8173-82.
2005: Thomas Hehlgans; Klaus Pfeffer
The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games.
Immunology 2005;115(1):1-20.
2005: Rudolf A Rupec; Franziska Jundt; Bernd Rebholz; Birgit Eckelt; Günther Weindl; Thomas Herzinger; Michael J Flaig; Sabine Moosmann; Gerd Plewig; Bernd Dörken; Irmgard Förster; Ralf Huss; Klaus Pfeffer
Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha.
Immunity 2005;22(4):479-91.
2005: Frank Wunderlich; Mohamed A Dkhil; Liv I Mehnert; Juliane V Braun; Manal El-Khadragy; Elena Borsch; Derik Hermsen; W Peter M Benten; Klaus Pfeffer; Horst Mossmann; Jürgen Krücken
Testosterone responsiveness of spleen and liver in female lymphotoxin beta receptor-deficient mice resistant to blood-stage malaria.
Microbes and infection / Institut Pasteur 2005;7(3):399-409.
2005: Yang Wang; Sumit K Subudhi; Robert A Anders; James W. Lo; Yonglian Sun; Sarah Blink; Yugang Wang; Jing Wang; Xiaojuan Liu; Karin Mink; Daniel Degrandi; Klaus Pfeffer; Yang-Xin Fu
The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses.
The Journal of clinical investigation 2005;115(3):711-7.
2005: Norbert Hüser; Christine Tertilt; Klaus Gerauer; Stefan Maier; Tobias Traeger; Volker Assfalg; Rudolf Reiter; Claus-Dieter Heidecke; Klaus Pfeffer
CCR4-deficient mice show prolonged graft survival in a chronic cardiac transplant rejection model.
European journal of immunology 2005;35(1):128-38.
2004: Anna Vossenkämper; Daniela Struck; Cosme Alvarado Esquivel; Tobias Went; Kioyshi Takeda; Shizuo Akira; Klaus Pfeffer; Gottfried Alber; Matthias Lochner; Irmgard Förster; Oliver Liesenfeld
Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control.
European journal of immunology 2004;34(11):3197-207.
2004: Stefan Maier; Tobias Traeger; Markus Entleutner; Alexandra Westerholt; Britta Kleist; Norbert Hüser; Bernhard Holzmann; Albrecht Stier; Klaus Pfeffer; Claus-Dieter Heidecke
Cecal ligation and puncture versus colon ascendens stent peritonitis: two distinct animal models for polymicrobial sepsis.
Shock (Augusta, Ga.) 2004;21(6):505-11.
2003: Robert Endres; Georg Häcker; Inge Brosch; Klaus Pfeffer
Apparently normal tumor necrosis factor receptor 1 signaling in the absence of the silencer of death domains.
Molecular and cellular biology 2003;23(18):6609-17.
2003: Thorsten Klamp; Ulrich Boehm; Daniela Schenk; Klaus Pfeffer; Jonathan C Howard
A giant GTPase, very large inducible GTPase-1, is inducible by IFNs.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(3):1255-65.
2003: Klaus Pfeffer
Biological functions of tumor necrosis factor cytokines and their receptors.
Cytokine & growth factor reviews 2003;14(3-4):185-91.
2003: Stefan Ehlers; Christoph Hölscher; Stefanie Scheu; Christine Tertilt; Thomas Hehlgans; Johanna Suwinski; Robert Endres; Klaus Pfeffer
The lymphotoxin beta receptor is critically involved in controlling infections with the intracellular pathogens Mycobacterium tuberculosis and Listeria monocytogenes.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):5210-8.
2003: Koichiro Abe; Felix O Yarovinsky; Takaya Murakami; Alexander N Shakhov; Alexei Tumanov; Daisuke Ito; Ludmila N Drutskaya; Klaus Pfeffer; Dmitry V Kuprash; Kristin L Komschlies; Sergei A Nedospasov
Distinct contributions of TNF and LT cytokines to the development of dendritic cells in vitro and their recruitment in vivo.
Blood 2003;101(4):1477-83.
2002: Dmitry V Kuprash; Marat B Alimzhanov; Alexei Tumanov; Sergei Grivennikov; Alexander N Shakhov; Ludmila N Drutskaya; Michael W Marino; Regina L Turetskaya; Arthur O. Anderson; Klaus Rajewsky; Klaus Pfeffer; Sergei A Nedospasov
Redundancy in tumor necrosis factor (TNF) and lymphotoxin (LT) signaling in vivo: mice with inactivation of the entire TNF/LT locus versus single-knockout mice.
Molecular and cellular biology 2002;22(24):8626-34.
2002: Evelyne Schaller; Alison J Macfarlane; Rudolf A Rupec; Siamon Gordon; Andrew J McKnight; Klaus Pfeffer
Inactivation of the F4/80 glycoprotein in the mouse germ line.
Molecular and cellular biology 2002;22(22):8035-43.
2002: Thomas Hehlgans; Benjamin Stoelcker; Peter Stopfer; Peter Müller; Grigore Cernaianu; Markus Guba; Markus Steinbauer; Sergei A Nedospasov; Klaus Pfeffer; Daniela N Männel
Lymphotoxin-beta receptor immune interaction promotes tumor growth by inducing angiogenesis.
Cancer research 2002;62(14):4034-40.
2002: Jing Wang; Amy Foster; Robert Chin; Ping Yu; Yonglian Sun; Yang Wang; Klaus Pfeffer; Yang-Xin Fu
The complementation of lymphotoxin deficiency with LIGHT, a newly discovered TNF family member, for the restoration of secondary lymphoid structure and function.
European journal of immunology 2002;32(7):1969-79.
2002: Stefanie Scheu; Judith Alferink; Tobias Pötzel; Winfried Barchet; Ulrich Kalinke; Klaus Pfeffer
Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis.
The Journal of experimental medicine 2002;195(12):1613-24.
2002: Stephan Paxian; Heidrun Merkle; Marc Riemann; Monika Wilda; Guido Adler; Horst Hameister; Susanne Liptay; Klaus Pfeffer; Roland M Schmid
Abnormal organogenesis of Peyer's patches in mice deficient for NF-kappaB1, NF-kappaB2, and Bcl-3.
Gastroenterology 2002;122(7):1853-68.
2002: Rudolph Reiter; Klaus Pfeffer
Impaired germinal centre formation and humoral immune response in the absence of CD28 and interleukin-4.
Immunology 2002;106(2):222-8.
2002: Ulrike Thalmaier; Norbert Lehn; Klaus Pfeffer; Manfred Stolte; Michael Vieth; Wulf Schneider-Brachert
Role of tumor necrosis factor alpha in Helicobacter pylori gastritis in tumor necrosis factor receptor 1-deficient mice.
Infection and immunity 2002;70(6):3149-55.
2001: A Schaub; A Fütterer; Klaus Pfeffer
PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily.
European journal of immunology 2001;31(12):3714-25.
2001: Irute Girkontaite; K Missy; Vadim Sakk; A Harenberg; Kerry Tedford; T Pötzel; Klaus Pfeffer; Klaus-Dieter Fischer
Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses.
Nature immunology 2001;2(9):855-62.
2001: Thomas Plitz; Klaus Pfeffer
Intact lysosome transport and phagosome function despite kinectin deficiency.
Molecular and cellular biology 2001;21(17):6044-55.
2001: S Maier; Christine Tertilt; N Chambron; Klaus Gerauer; Norbert Hüser; Claus-Dieter Heidecke; Klaus Pfeffer
Inhibition of natural killer cells results in acceptance of cardiac allografts in CD28-/- mice.
Nature medicine 2001;7(5):557-62.
2001: Qiang Wu; Yonglian Sun; Jun Wang; Xiaoqi Lin; Youli Wang; L E Pegg; A Fütterer; Klaus Pfeffer; Yang-Xin Fu
Signal via lymphotoxin-beta R on bone marrow stromal cells is required for an early checkpoint of NK cell development.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1684-9.
2000: Klaus Pfeffer
Morphogenic and host protective functions executed by tumor necrosis factor receptors, lymphotoxin receptors and their ligands.
European cytokine network 2000;11(3):514.
2000: Stefan Maier; Klaus Emmanuilidis; Markus Entleutner; N Zantl; M Werner; Klaus Pfeffer; Claus-Dieter Heidecke
Massive chemokine transcription in acute renal failure due to polymicrobial sepsis.
Shock (Augusta, Ga.) 2000;14(2):187-92.
2000: Stefan Ehlers; S Kutsch; E M Ehlers; J Benini; Klaus Pfeffer
Lethal granuloma disintegration in mycobacteria-infected TNFRp55-/- mice is dependent on T cells and IL-12.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):483-92.
2000: P Hochholzer; Grayson Lipford; Hermann Wagner; Klaus Pfeffer; Klaus Heeg
Role of interleukin-18 (IL-18) during lethal shock: decreased lipopolysaccharide sensitivity but normal superantigen reaction in IL-18-deficient mice.
Infection and immunity 2000;68(6):3502-8.
1999: Dmitry V Kuprash; Marat B Alimzhanov; Alexei Tumanov; Arthur O. Anderson; Klaus Pfeffer; Sergei A Nedospasov
TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6575-80.
1999: Stefan Ehlers; J Benini; S Kutsch; R Endres; Ernst Th Rietschel; Klaus Pfeffer
Fatal granuloma necrosis without exacerbated mycobacterial growth in tumor necrosis factor receptor p55 gene-deficient mice intravenously infected with Mycobacterium avium.
Infection and immunity 1999;67(7):3571-9.
1999: B Neumann; N Zantl; A Veihelmann; Klaus Emmanuilidis; Klaus Pfeffer; Claus-Dieter Heidecke; Bernhard Holzmann
Mechanisms of acute inflammatory lung injury induced by abdominal sepsis.
International immunology 1999;11(2):217-27.
1999: Thomas Plitz; U Huffstadt; Robert Endres; E Schaller; T W Mak; Hermann Wagner; Klaus Pfeffer
The resistance against Listeria monocytogenes and the formation of germinal centers depend on a functional death domain of the 55 kDa tumor necrosis factor receptor.
European journal of immunology 1999;29(2):581-91.
1999: Robert Endres; Marat B Alimzhanov; Thomas Plitz; A Fütterer; Marie H Kosco-Vilbois; Sergei A Nedospasov; Klaus Rajewsky; Klaus Pfeffer
Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells.
The Journal of experimental medicine 1999;189(1):159-68.
1998: Ulrich Boehm; Lisbeth A Guethlein; Thorsten Klamp; K Ozbek; A Schaub; A Fütterer; Klaus Pfeffer; Jonathan C Howard
Two families of GTPases dominate the complex cellular response to IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6715-23.
1998: A Fütterer; K Mink; A Luz; Marie H Kosco-Vilbois; Klaus Pfeffer
The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues.
Immunity 1998;9(1):59-70.
1998: H Neubauer; A Cumano; M Müller; H Wu; U Huffstadt; Klaus Pfeffer
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis.
Cell 1998;93(3):397-409.
1998: N Zantl; A Uebe; B Neumann; Hermann Wagner; Jörg Rüdiger Siewert; Bernhard Holzmann; Claus-Dieter Heidecke; Klaus Pfeffer
Essential role of gamma interferon in survival of colon ascendens stent peritonitis, a novel murine model of abdominal sepsis.
Infection and immunity 1998;66(5):2300-9.
1997: Robert Endres; A Luz; H Schulze; H Neubauer; A Fütterer; S M Holland; Hermann Wagner; Klaus Pfeffer
Listeriosis in p47(phox-/-) and TRp55-/- mice: protection despite absence of ROI and susceptibility despite presence of RNI.
Immunity 1997;7(3):419-32.
1997: Marat B Alimzhanov; Dmitry V Kuprash; Marie H Kosco-Vilbois; A Luz; Regina L Turetskaya; A Tarakhovsky; Klaus Rajewsky; Sergei A Nedospasov; Klaus Pfeffer
Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):9302-7.
1996: DE Speiser; E Sebzda; Toshiaki Ohteki; Martin F Bachmann; Klaus Pfeffer; Tak W Mak; Pamela S Ohashi
Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo.
European journal of immunology 1996;26(12):3055-60.
1996: B Neumann; A Luz; Klaus Pfeffer; Bernhard Holzmann
Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor.
The Journal of experimental medicine 1996;184(1):259-64.
1996: B Neumann; thomas machleidt; A Lifka; Klaus Pfeffer; D Vestweber; T W Mak; Bernhard Holzmann; M Krönke
Crucial role of 55-kilodalton TNF receptor in TNF-induced adhesion molecule expression and leukocyte organ infiltration.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(4):1587-93.
1995: L M Boucher; Katja Wiegmann; A Fütterer; Klaus Pfeffer; thomas machleidt; Stefan Schütze; T W Mak; M Krönke
CD28 signals through acidic sphingomyelinase.
The Journal of experimental medicine 1995;181(6):2059-68.
1993: Takeshi Matsuyama; T Kimura; M Kitagawa; Klaus Pfeffer; T Kawakami; N Watanabe; TM Kündig; R Amakawa; Kenji Kishihara; Andrew Wakeham
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development.
Cell 1993;75(1):83-97.
1993: Arda Shahinian; Klaus Pfeffer; K P Lee; TM Kündig; Kenji Kishihara; Andrew Wakeham; K Kawai; Pamela S Ohashi; Craig Thompson; Tak W Mak
Differential T cell costimulatory requirements in CD28-deficient mice.
Science (New York, N.Y.) 1993;261(5121):609-12.
1993: Kenji Kishihara; Josef M Penninger; V A Wallace; TM Kündig; K Kawai; Andrew Wakeham; E Timms; Klaus Pfeffer; Pamela S Ohashi; M L Thomas
Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice.
Cell 1993;74(1):143-56.
1993: Klaus Pfeffer; Takeshi Matsuyama; TM Kündig; Andrew Wakeham; Kenji Kishihara; Arda Shahinian; Katja Wiegmann; Pamela S Ohashi; M Krönke; Tak W Mak
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection.
Cell 1993;73(3):457-67.