Uwe Pfüller

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Thies A; Dautel P; Meyer A; Pfüller U; Schumacher U
Low-dose mistletoe lectin-I reduces melanoma growth and spread in a scid mouse xenograft model.
Thies Anka; Berlin Anke; Brunner Georg; Schulze Hans-Joachim; Moll Ingrid; Pfüller Uwe; Wagener Christoph; Schachner Melitta; Altevogt Peter; Schumacher Udo
Glycoconjugate profiling of primary melanoma and its sentinel node and distant metastases: implications for diagnosis and pathophysiology of metastases.
Jäger Sebastian; Winkler Karin; Pfüller Uwe; Scheffler Armin
Solubility studies of oleanolic acid and betulinic acid in aqueous solutions and plant extracts of Viscum album L.

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All Publications

2008: Thies A; Dautel P; Meyer A; Pfüller U; Schumacher U
Low-dose mistletoe lectin-I reduces melanoma growth and spread in a scid mouse xenograft model.
British journal of cancer 2008;98(1):106-12.
2007: Thies Anka; Berlin Anke; Brunner Georg; Schulze Hans-Joachim; Moll Ingrid; Pfüller Uwe; Wagener Christoph; Schachner Melitta; Altevogt Peter; Schumacher Udo
Glycoconjugate profiling of primary melanoma and its sentinel node and distant metastases: implications for diagnosis and pathophysiology of metastases.
Cancer letters 2007;248(1):68-80.
2007: Jäger Sebastian; Winkler Karin; Pfüller Uwe; Scheffler Armin
Solubility studies of oleanolic acid and betulinic acid in aqueous solutions and plant extracts of Viscum album L.
Planta medica 2007;73(2):157-62.
2007: Freudlsperger Christian; Thies Anka; Pfüller Uwe; Schumacher Udo
The proteasome inhibitor bortezomib augments anti-proliferative effects of mistletoe lectin-I and the PPAR-gamma agonist rosiglitazone in human melanoma cells.
Anticancer research 2007;27(1A):207-13.
2006: Giudici Marcela; Poveda José Antonio; Molina María Luisa; de la Canal Laura; González-Ros José M; Pfüller Karola; Pfüller Uwe; Villalaín José
Antifungal effects and mechanism of action of viscotoxin A3.
The FEBS journal 2006;273(1):72-83.
2005: Pohlmeyer I; Jörns J; Schumacher U; Van Damme E J M; Peumans W J; Pfüller U; Neumann U
Lectin histochemical investigations of the distal gut of chicks with special emphasis on the follicle-associated epithelium.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 2005;52(3):138-46.
2005: Thies Anka; Nugel Dirk; Pfüller Uwe; Moll Ingrid; Schumacher Udo
Influence of mistletoe lectins and cytokines induced by them on cell proliferation of human melanoma cells in vitro.
Toxicology 2005;207(1):105-16.
2004: Pevzner Irina B; Agapov Igor I; Niwa Hideaki; Maluchenko Natalia V; Moisenovich Mikhail M; Pfüller Uwe; Tonevitsky Alexander G
Differences in amino acid sequences of mistletoe lectin I and III B-subunits determining carbohydrate binding specificity.
Biochimica et biophysica acta 2004;1675(1-3):155-64.
2004: Wacker Roland; Stoeva Stanka; Pfüller Karola; Pfüller Uwe; Voelter Wolfgang
Complete structure determination of the A chain of mistletoe lectin III from Viscum album L. ssp. album.
Journal of peptide science : an official publication of the European Peptide Society 2004;10(3):138-48.
2004: Tonevitsky Alexander G; Agapov Igor I; Pevzner Irina B; Maluchenko Nataliya V; Moisenovich Mikhail M; Palmer Rex A; Yurkova M; Pfüller Karola; Pfüller Uwe
A new gene encoding the ribosome-inactivating protein from mistletoe extracts.
Arzneimittel-Forschung 2004;54(4):242-9.
2004: Pryme Ian F; Bardocz Susan; Pusztai Arpad; Ewen Stanley W; Pfüller Uwe
A mistletoe lectin (ML-1)-containing diet reduces the viability of a murine non-Hodgkin lymphoma tumor.
Cancer detection and prevention 2004;28(1):52-6.
2003: Giudici Marcela; Pascual Roberto; de la Canal Laura; Pfüller Karola; Pfüller Uwe; Villalaín José
Interaction of viscotoxins A3 and B with membrane model systems: implications to their mechanism of action.
Biophysical journal 2003;85(2):971-81.
2003: Niwa Hideaki; Tonevitsky Alexander G; Agapov Igor I; Saward Steve; Pfüller Uwe; Palmer Rex A
Crystal structure at 3 A of mistletoe lectin I, a dimeric type-II ribosome-inactivating protein, complexed with galactose.
European journal of biochemistry / FEBS 2003;270(13):2739-49.
2003: Jörns Julia; Mangold Ulrich; Neumann Ulrich; Van Damme Els J M; Peumans Willy J; Pfüller Uwe; Schumacher Udo
Lectin histochemistry of the lymphoid organs of the chicken.
Anatomy and embryology 2003;207(1):85-94.
2003: Baintner K; Kiss P; Pfüller U; Bardocz Susan; Pusztai A
Effect of orally and intraperitoneally administered plant lectins on food consumption of rats.
Acta physiologica Hungarica 2003;90(2):97-107.
2002: Lavelle E C; Grant G; Pusztai A; Pfüller U; Leavy O; McNeela E; Mills K H G; O'Hagan D T
Mistletoe lectins enhance immune responses to intranasally co-administered herpes simplex virus glycoprotein D2.
Immunology 2002;107(2):268-74.
2002: Valentiner Ursula; Pfüller Uwe; Baum Christopher; Schumacher Udo
The cytotoxic effect of mistletoe lectins I, II and III on sensitive and multidrug resistant human colon cancer cell lines in vitro.
Toxicology 2002;171(2-3):187-99.
2001: Thies A; Pfüller U; Schachner M; Horny H P; Molls I; Schumacher U
Binding of mistletoe lectins to cutaneous malignant melanoma: implications for prognosis and therapy.
Anticancer research 2001;21(4B):2883-7.
2001: Lavelle E C; Grant G; Pusztai A; Pfüller U; O'Hagan D T
The identification of plant lectins with mucosal adjuvant activity.
Immunology 2001;102(1):77-86.
2000: Stein G M; Pfüller U; Schietzel M; Büssing A
Expression of interleukin-4 in apoptotic cells: stimulation of the type-2 cytokine by different toxins in human peripheral blood mononuclear and tumor cells.
Cytometry 2000;41(4):261-70.
2000: Stein G M; Pfüller U; Schietzel M; Büssing A
Intracellular expression of IL-4 and inhibition of IFN-gamma by extracts from European mistletoe is related to induction of apoptosis.
Anticancer research 2000;20(5A):2987-94.
2000: Edlund U; Hensel A; Fröse D; Pfüller U; Scheffler A
Polysaccharides from fresh Viscum album L. berry extract and their interaction with Viscum album agglutinin I.
Arzneimittel-Forschung 2000;50(7):645-51.
2000: Stein G M; Pfüller U; Schietzel M; Büssing A
Toxic proteins from European mistletoe (Viscum album L.): increase of intracellular IL-4 but decrease of IFN-gamma in apoptotic cells.
Anticancer research 2000;20(3A):1673-8.
2000: Vervecken W; Kleff S; Pfüller U; Büssing A
Induction of apoptosis by mistletoe lectin I and its subunits. No evidence for cytotoxic effects caused by isolated A- and B-chains.
The international journal of biochemistry & cell biology 2000;32(3):317-26.
2000: Lavelle E C; Grant G; Pusztai A; Pfüller U; O'Hagan D T
Mucosal immunogenicity of plant lectins in mice.
Immunology 2000;99(1):30-7.
1999: Büssing A; Stein G M; Pfüller U; Schietzel M
Differential binding of toxic lectins from Viscum album L., ML I and ML III, to human lymphocytes.
Anticancer research 1999;19(6B):5095-9.
1999: Büssing A; Vervecken W; Wagner M; Wagner B; Pfüller U; Schietzel M
Expression of mitochondrial Apo2.7 molecules and caspase-3 activation in human lymphocytes treated with the ribosome-inhibiting mistletoe lectins and the cell membrane permeabilizing viscotoxins.
Cytometry 1999;37(2):133-9.
1999: Stein G M; Edlund U; Pfüller U; Büssing A; Schietzel M
Influence of polysaccharides from Viscum album L. on human lymphocytes, monocytes and granulocytes in vitro.
Anticancer research 1999;19(5B):3907-14.
1999: Büssing A; Stein G M; Herterich-Akinpelu I; Pfüller U
Apoptosis-associated generation of reactive oxygen intermediates and release of pro-inflammatory cytokines in human lymphocytes and granulocytes by extracts from the seeds of Acalypha wilkesiana.
Journal of ethnopharmacology 1999;66(3):301-9.
1999: Stein G M; Pfüller U; Schietzel M
Viscotoxin-free aqueous extracts from European mistletoe (Viscum album L.) stimulate activity of human granulocytes.
Anticancer research 1999;19(4B):2925-8.
1999: Büssing A; Stein G M; Pfüller U; Schietzel M
Induction of Fas ligand (CD95L) by the toxic mistletoe lectins in human lymphocytes.
Anticancer research 1999;19(3A):1785-90.
1999: Büssing A; Wagner M; Wagner B; Stein G M; Schietzel M; Schaller G; Pfüller U
Induction of mitochondrial Apo2.7 molecules and generation of reactive oxygen-intermediates in cultured lymphocytes by the toxic proteins from Viscum album L.
Cancer letters 1999;139(1):79-88.
1999: Büssing A; Stein G M; Wagner M; Wagner B; Schaller G; Pfüller U; Schietzel M
Accidental cell death and generation of reactive oxygen intermediates in human lymphocytes induced by thionins from Viscum album L.
European journal of biochemistry / FEBS 1999;262(1):79-87.
1999: Stein G M; Schaller G; Pfüller U; Schietzel M; Büssing A
Thionins from Viscum album L: influence of the viscotoxins on the activation of granulocytes.
Anticancer research 1999;19(2A):1037-42.
1999: Stein G M; Pfüller U; Berg P A
Recognition of different antigens of mistletoe extracts by anti-mistletoe lectin antibodies.
Cancer letters 1999;135(2):165-70.
1999: Stein G M; Schaller G; Pfüller U; Wagner M; Wagner B; Schietzel M; Büssing A
Characterisation of granulocyte stimulation by thionins from European mistletoe and from wheat.
Biochimica et biophysica acta 1999;1426(1):80-90.
1998: Büssing A; Schaller G; Pfüller U
Generation of reactive oxygen intermediates (ROI) by the thionins from Viscum album L.
Anticancer research 1998;18(6A):4291-6.
1998: Büssing A; Multani A S; Pathak S; Pfüller U; Schietzel M
Induction of apoptosis by the N-acetyl-galactosamine-specific toxic lectin from Viscum album L. is associated with a decrease of nuclear p53 and Bcl-2 proteins and induction of telomeric associations.
Cancer letters 1998;130(1-2):57-68.
1998: Büssing A; Stein G M; Pfüller U
Selective killing of CD8+ cells with a 'memory' phenotype (CD62Llo) by the N-acetyl-D-galactosamine-specific lectin from Viscum album L.
Cell death and differentiation 1998;5(3):231-40.
1996: Büssing A; Suzart K; Bergmann J; Pfüller U; Schietzel M; Schweizer K
Induction of apoptosis in human lymphocytes treated with Viscum album L. is mediated by the mistletoe lectins.
Cancer letters 1996;99(1):59-72.

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Uwe Pfüller

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