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Susan Phare

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Michael J Coffey; Susan M Phare; Ming Luo; Marc Peters-Golden
Guanylyl cyclase and protein kinase G mediate nitric oxide suppression of 5-lipoxygenase metabolism in rat alveolar macrophages.
Michael J Coffey; Carlos H Serezani; Susan M Phare; Nicolas Flamand; Marc Peters-Golden
NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.
Michael J Coffey; Susan M Phare; Marc Peters-Golden
Induction of inducible nitric oxide synthase by lipopolysaccharide/interferon gamma and sepsis down-regulates 5-lipoxygenase metabolism in murine alveolar macrophages.

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All Publications

2008: Michael J Coffey; Susan M Phare; Ming Luo; Marc Peters-Golden
Guanylyl cyclase and protein kinase G mediate nitric oxide suppression of 5-lipoxygenase metabolism in rat alveolar macrophages.
Biochimica et biophysica acta 2008;1781(6-7):299-305.
2007: Michael J Coffey; Carlos H Serezani; Susan M Phare; Nicolas Flamand; Marc Peters-Golden
NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis.
Journal of leukocyte biology 2007;82(6):1585-91.
2004: Michael J Coffey; Susan M Phare; Marc Peters-Golden
Induction of inducible nitric oxide synthase by lipopolysaccharide/interferon gamma and sepsis down-regulates 5-lipoxygenase metabolism in murine alveolar macrophages.
Experimental lung research 2004;30(7):615-33.
2004: Ming Luo; Sandra M Jones; Susan M Phare; Michael J Coffey; Marc Peters-Golden; Thomas G Brock
Protein kinase A inhibits leukotriene synthesis by phosphorylation of 5-lipoxygenase on serine 523.
The Journal of biological chemistry 2004;279(40):41512-20.
2004: Michael J Coffey; Susan M Phare; Marc Peters-Golden
Role of leukotrienes in killing of Mycobacterium bovis by neutrophils.
Prostaglandins, leukotrienes, and essential fatty acids 2004;71(3):185-90.
2003: Daniel Kaul; Michael J Coffey; Susan M Phare; Powel Kazanjian
Capacity of neutrophils and monocytes from human immunodeficiency virus-infected patients and healthy controls to inhibit growth of Mycobacterium bovis.
The Journal of laboratory and clinical medicine 2003;141(5):330-4.
2002: Michael J Coffey; Susan M Phare; Marc Peters-Golden
Interaction between nitric oxide, reactive oxygen intermediates, and peroxynitrite in the regulation of 5-lipoxygenase metabolism.
Biochimica et biophysica acta 2002;1584(2-3):81-90.
2002: Peter Mancuso; Andrew Gottschalk; Susan M Phare; Marc Peters-Golden; Nicholas W Lukacs; Gary B Huffnagle
Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4018-24.
2001: Robert Paine; Susan B Morris; Hong Jin; Steven E Wilcoxen; Susan M Phare; Bethany B Moore; Michael J Coffey; Galen Toews
Impaired functional activity of alveolar macrophages from GM-CSF-deficient mice.
American journal of physiology. Lung cellular and molecular physiology 2001;281(5):L1210-8.
2001: Michael J Coffey; Susan M Phare; Marc Peters-Golden
Peroxynitrite-induced nitrotyrosination of proteins is blocked by direct 5-lipoxygenase inhibitor zileuton.
The Journal of pharmacology and experimental therapeutics 2001;299(1):198-203.
2001: Raju C Reddy; Gwo-Hsiao Chen; Kazuhiro Tateda; Wan C Tsai; Susan M Phare; Peter Mancuso; Marc Peters-Golden; Theodore J Standiford
Selective inhibition of COX-2 improves early survival in murine endotoxemia but not in bacterial peritonitis.
American journal of physiology. Lung cellular and molecular physiology 2001;281(3):L537-43.
2001: Mairi Catherine Noverr; Susan M Phare; Galen Toews; Michael J Coffey; Gary B Huffnagle
Pathogenic yeasts Cryptococcus neoformans and Candida albicans produce immunomodulatory prostaglandins.
Infection and immunity 2001;69(5):2957-63.
2000: Bethany B Moore; Michael J Coffey; Paul J Christensen; S Sitterding; R Ngan; Carol A Wilke; R McDonald; Susan M Phare; Marc Peters-Golden; Robert Paine; Galen Toews
GM-CSF regulates bleomycin-induced pulmonary fibrosis via a prostaglandin-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(7):4032-9.
2000: Michael J Coffey; Susan M Phare; Marc Peters-Golden
Prolonged exposure to lipopolysaccharide inhibits macrophage 5-lipoxygenase metabolism via induction of nitric oxide synthesis.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(7):3592-8.
1999: Michael J Coffey; Susan M Phare; Sandro Cinti; Marc Peters-Golden; Powel Kazanjian
Granulocyte-macrophage colony-stimulating factor upregulates reduced 5-lipoxygenase metabolism in peripheral blood monocytes and neutrophils in acquired immunodeficiency syndrome.
Blood 1999;94(11):3897-905.
1999: Michael J Coffey; Susan M Phare; Marc Peters-Golden; Gary B Huffnagle
Regulation of 5-lipoxygenase metabolism in mononuclear phagocytes by CD4 T lymphocytes.
Experimental lung research 1999;25(7):617-29.
1998: Susan M Phare; Marc Peters-Golden; Michael J Coffey
Alveolar lining fluid regulates mononuclear phagocyte 5-lipoxygenase metabolism.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(5):1141-6.
1998: Michael J Coffey; Susan M Phare; S George; Marc Peters-Golden; Powel Kazanjian
Granulocyte colony-stimulating factor administration to HIV-infected subjects augments reduced leukotriene synthesis and anticryptococcal activity in neutrophils.
The Journal of clinical investigation 1998;102(4):663-70.
1997: Michael J Coffey; C Woffendin; Susan M Phare; Robert M Strieter; David M Markovitz
RANTES inhibits HIV-1 replication in human peripheral blood monocytes and alveolar macrophages.
The American journal of physiology 1997;272(5 Pt 1):L1025-9.
1996: Michael J Coffey; Susan M Phare; Powel Kazanjian; Marc Peters-Golden
5-Lipoxygenase metabolism in alveolar macrophages from subjects infected with the human immunodeficiency virus.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(1):393-9.
1996: Thomas G Brock; Robert W McNish; Michael J Coffey; Tammy Clark Ojo; Susan M Phare; Marc Peters-Golden
Effects of granulocyte-macrophage colony-stimulating factor on eicosanoid production by mononuclear phagocytes.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(7):2522-7.
1994: Michael J Coffey; Steven E Wilcoxen; Susan M Phare; robert simpson; Margaret R Gyetko; Marc Peters-Golden
Reduced 5-lipoxygenase metabolism of arachidonic acid in macrophages rrom 1,25-dihydroxyvitamin D3-deficient rats.
Prostaglandins 1994;48(5):313-29.