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Hemali Phatnani

Research Profile

Chemicals & Drugs

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Saccharomyces cerevisiae

Physiology

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Amino Acid Sequences

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Protein Interaction Mapping

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Publications

TOP 3
Andrea Serio; Christopher E Shaw; Carole Shum; Rick Siller; David Story; Ian Wilmut; Chen Zhao; Dale Michael Ando; Sami J Barmada; Bilada Bilican; Karen Burr; Monica A Carrasco; Steven Finkbeiner; Ghazal Haghi; Tom Maniatis; Agnes Lumi Nishimura; Hemali P Phatnani; Siddharthan Chandran
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Hemali P Phatnani; Juan Carlos Tapia; Monica A Carrasco; Brad A Friedman; Paolo Guarnieri; Sarah K Meadows; Michael Muratet; Richard M Myers; Kimberly M Newberry; Chiamaka Nwakeze; Sean O'Keeffe; Florencia Pauli-Behn; Tom Maniatis
Intricate interplay between astrocytes and motor neurons in ALS.
André Möller; Jürgen K Naggert; Hemali P Phatnani; M Madan Babu; Gayle B Collin; Arno L Greenleaf; Fabian Hosp; Sonya James; Benjamin Lang; Francisco Ramirez; Matthias Selbach; Sheila Q Xie; Ana Pombo
Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease.

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All Publications

2013: Andrea Serio; Christopher E Shaw; Carole Shum; Rick Siller; David Story; Ian Wilmut; Chen Zhao; Dale Michael Ando; Sami J Barmada; Bilada Bilican; Karen Burr; Monica A Carrasco; Steven Finkbeiner; Ghazal Haghi; Tom Maniatis; Agnes Lumi Nishimura; Hemali P Phatnani; Siddharthan Chandran
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(12):4697-702.
2013: Hemali P Phatnani; Juan Carlos Tapia; Monica A Carrasco; Brad A Friedman; Paolo Guarnieri; Sarah K Meadows; Michael Muratet; Richard M Myers; Kimberly M Newberry; Chiamaka Nwakeze; Sean O'Keeffe; Florencia Pauli-Behn; Tom Maniatis
Intricate interplay between astrocytes and motor neurons in ALS.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(8):E756-65.
2012: André Möller; Jürgen K Naggert; Hemali P Phatnani; M Madan Babu; Gayle B Collin; Arno L Greenleaf; Fabian Hosp; Sonya James; Benjamin Lang; Francisco Ramirez; Matthias Selbach; Sheila Q Xie; Ana Pombo
Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease.
Molecular & cellular proteomics : MCP 2012;11(6):M111.011767.
2012: Bilada Bilican; Monica Carrasco; Sami J Barmada; George Q Daley; Steven Finkbeiner; Judy Fletcher; Brad A Friedman; Giles E Hardingham; Tom Maniatis; Agnes Lumi Nishimura; In-Hyun Park; Hemali P Phatnani; Clare A Puddifoot; Andrea Serio; Christopher E Shaw; David Story; Gareth J Sullivan; Ian Wilmut; David J A Wyllie; Siddharthan Chandran
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(15):5803-8.
2010: Bartlomiej Bartkowiak; Pengda Liu; Hemali P Phatnani; Nicholas J Fuda; Jeffrey J Cooper; David H Price; Karen Adelman; John T Lis; Arno L Greenleaf
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1.
Genes & development 2010;24(20):2303-16.
2010: Jianhong Wu; Hemali P Phatnani; Tao-shih Hsieh; Arno L Greenleaf
The phosphoCTD-interacting domain of Topoisomerase I.
Biochemical and biophysical research communications 2010;397(1):117-9.
2008: Craig B Bennett; Tammy J Westmoreland; Carmel S Verrier; Carrie Blanchette; Tiffany L Sabin; Hemali P Phatnani; Yuliya V Mishina; Gudrun Huper; Alice L Selim; Ernest R Madison; Dominique D Bailey; Adebola I Falae; Alvaro Galli; John Olson; Arno L Greenleaf; Jeffrey R Marks
Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.
PloS one 2008;3(1):e1448.
2006: Hemali P Phatnani; Arno L Greenleaf
Phosphorylation and functions of the RNA polymerase II CTD.
Genes & development 2006;20(21):2922-36.
2006: Ming Li; Hemali P Phatnani; Arno L Greenleaf; Pei Zhou
NMR assignment of the SRI domain of human Set2/HYPB.
Journal of biomolecular NMR 2006;36 Suppl 1():5.
2005: Ming Li; Hemali P Phatnani; Ziqiang Guan; Harvey Sage; Arno L Greenleaf; Pei Zhou
Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(49):17636-41.
2005: Kelby O Kizer; Hemali P Phatnani; Yoichiro Shibata; Hana Hall; Arno L Greenleaf; Brian D Strahl
A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation.
Molecular and cellular biology 2005;25(8):3305-16.
2004: Hemali P Phatnani; Janice C Jones; Arno L Greenleaf
Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome.
Biochemistry 2004;43(50):15702-19.
2004: Janice C Jones; Hemali P Phatnani; Timothy A J Haystead; Justin A MacDonald; S Munir Alam; Arno L Greenleaf
C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats.
The Journal of biological chemistry 2004;279(24):24957-64.
2004: Hemali P Phatnani; Arno L Greenleaf
Identifying phosphoCTD-associating proteins.
Methods in molecular biology (Clifton, N.J.) 2004;257():17-28.
1999: Daniel P Morris; Hemali P Phatnani; Arno L Greenleaf
Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-End formation.
The Journal of biological chemistry 1999;274(44):31583-7.