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James Phillips

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Hao Liu; Justin Manuel; M James Phillips; Itay Shalev; Peter S Yang; Jianhua Zhang; Li Zhang; Tina Zhu; Myron I Cybulsky; David R Grant; Wei He; Gary A Levy
Characterization of fibrinogen-like protein 2 (FGL2): monomeric FGL2 has enhanced immunosuppressive activity in comparison to oligomeric FGL2.
Itay Shalev; Kit Man Wong; Katharina Foerster; Yi Zhu; Cecilia Chan; Asif Maknojia; Jianhua Zhang; Xue-Zhong Ma; Xiao Chun Yang; Julia Fang Gao; Hao Liu; Nazia Selzner; David A Clark; Oyedele Adeyi; M James Phillips; Reginald R Gorczynski; David Grant; Ian D McGilvray; Gary Levy
The novel CD4+CD25+ regulatory T cell effector molecule fibrinogen-like protein 2 contributes to the outcome of murine fulminant viral hepatitis.
Itay Shalev; Hao Liu; Cheryl Koscik; Agata Bartczak; Mojib Javadi; Kit Man Wong; Asif Maknojia; Wei He; Ming Feng Liu; Jun Diao; Erin Winter; Justin Manuel; Doug McCarthy; Mark S Cattral; Jennifer L Gommerman; David A Clark; M James Phillips; Reginald R Gorczynski; Li Zhang; Greg Downey; David Grant; Myron I Cybulsky; Gary Levy
Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis.

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2013: Hao Liu; Justin Manuel; M James Phillips; Itay Shalev; Peter S Yang; Jianhua Zhang; Li Zhang; Tina Zhu; Myron I Cybulsky; David R Grant; Wei He; Gary A Levy
Characterization of fibrinogen-like protein 2 (FGL2): monomeric FGL2 has enhanced immunosuppressive activity in comparison to oligomeric FGL2.
The international journal of biochemistry & cell biology 2013;45(2):408-18.
2009: Itay Shalev; Kit Man Wong; Katharina Foerster; Yi Zhu; Cecilia Chan; Asif Maknojia; Jianhua Zhang; Xue-Zhong Ma; Xiao Chun Yang; Julia Fang Gao; Hao Liu; Nazia Selzner; David A Clark; Oyedele Adeyi; M James Phillips; Reginald R Gorczynski; David Grant; Ian D McGilvray; Gary Levy
The novel CD4+CD25+ regulatory T cell effector molecule fibrinogen-like protein 2 contributes to the outcome of murine fulminant viral hepatitis.
Hepatology (Baltimore, Md.) 2009;49(2):387-97.
2008: Itay Shalev; Hao Liu; Cheryl Koscik; Agata Bartczak; Mojib Javadi; Kit Man Wong; Asif Maknojia; Wei He; Ming Feng Liu; Jun Diao; Erin Winter; Justin Manuel; Doug McCarthy; Mark S Cattral; Jennifer L Gommerman; David A Clark; M James Phillips; Reginald R Gorczynski; Li Zhang; Greg Downey; David Grant; Myron I Cybulsky; Gary Levy
Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):249-60.
2007: Junwu Mu; Dawei Qu; Agata Bartczak; M James Phillips; Justin Manuel; Wei He; Cheryl Koscik; Michael Mendicino; Li Zhang; David A Clark; David R Grant; Peter H Backx; Gary A Levy; S Lee Adamson
Fgl2 deficiency causes neonatal death and cardiac dysfunction during embryonic and postnatal development in mice.
Physiological genomics 2007;31(1):53-62.
2006: Nadine De Albuquerque; Ehtesham Baig; Xuezhong Ma; Jianhua Zhang; William He; Andrea Rowe; Marlena Habal; Mingfeng Liu; Itay Shalev; Gregory P Downey; Reginald Gorczynski; Jagdish Butany; Julian L Leibowitz; Susan R Weiss; Ian D McGilvray; M James Phillips; Eleanor N Fish; Gary A Levy
Murine hepatitis virus strain 1 produces a clinically relevant model of severe acute respiratory syndrome in A/J mice.
Journal of virology 2006;80(21):10382-94.
2006: Mingfeng Liu; Michael Mendicino; Qin Ning; Anand Ghanekar; Wei He; Ian D McGilvray; Itay Shalev; David Pivato; David A Clark; M James Phillips; Gary A Levy
Cytokine-induced hepatic apoptosis is dependent on FGL2/fibroleukin: the role of Sp1/Sp3 and STAT1/PU.1 composite cis elements.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):7028-38.
2006: Gary A Levy; Gord Adamson; M James Phillips; Louise A Scrocchi; Laisum Fung; Pieter Biessels; Nancy F Ng; Anand Ghanekar; Andrea Rowe; Max Xuezhong Ma; Adam Levy; Cheryl Koscik; William He; Reginald Gorczynski; Steve Brookes; Caroline Woods; Ian D McGilvray; David Bell
Targeted delivery of ribavirin improves outcome of murine viral fulminant hepatitis via enhanced anti-viral activity.
Hepatology (Baltimore, Md.) 2006;43(3):581-91.
2006: Nadine DeAlbuquerque; Ehtesham Baig; Max Xuezhong; Itay Shalev; M James Phillips; Marlena Habal; Julian L Leibowitz; Ian D McGilvray; Jagdish Butany; Eleanor N Fish; Gary Levy
Murine hepatitis virus strain 1 as a model for severe acute respiratory distress syndrome (SARS).
Advances in experimental medicine and biology 2006;581():373-8.
2005: Michael Mendicino; MingFeng Liu; Anand Ghanekar; Wei He; Cheryl Koscik; Itay Shalev; Mojib Javadi; Julie Turnbull; Wenhao Chen; Laisum Fung; Seisuke Sakamoto; Phillip Marsden; Thomas K Waddell; M James Phillips; Reginald Gorczynski; Gary A Levy; David Grant
Targeted deletion of Fgl-2/fibroleukin in the donor modulates immunologic response and acute vascular rejection in cardiac xenografts.
Circulation 2005;112(2):248-56.
2004: Anand Ghanekar; Michael Mendicino; Hao Liu; Wei He; Mingfeng Liu; Robert Zhong; M James Phillips; Gary A Levy; David R Grant
Endothelial induction of fgl2 contributes to thrombosis during acute vascular xenograft rejection.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(9):5693-701.
2003: Kevin J Young; Lyndsey S Kay; M James Phillips; Li Zhang
Antitumor activity mediated by double-negative T cells.
Cancer research 2003;63(22):8014-21.
2003: M James Phillips; Toshifumi Azuma; Sheue-Lim M Meredith; Jeremy A Squire; Cameron Ackerley; Fred G Pluthero; Eve A Roberts; Riccardo A Superina; Gary A Levy; Philip A Marsden
Abnormalities in villin gene expression and canalicular microvillus structure in progressive cholestatic liver disease of childhood.
Lancet 2003;362(9390):1112-9.
2003: Philip A Marsden; Qin Ning; Laisum Fung; Xiaoping Luo; Yue Chen; Michael Mendicino; Anand Ghanekar; Jeremy A Scott; Teresa Miller; Camie W Y Chan; Matthew W C Chan; Wei He; Reginald M Gorczynski; David R Grant; David A Clark; M James Phillips; Gary A Levy
The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitis.
The Journal of clinical investigation 2003;112(1):58-66.
2003: Kevin J Young; Barb DuTemple; M James Phillips; Li Zhang
Inhibition of graft-versus-host disease by double-negative regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):134-41.
2003: Robert Zhong; Yigang Luo; Hongji Yang; Bertha Garcia; Anand Ghanekar; Patrick P W Luke; Subrata Chakrabarti; Ginette Lajoie; M James Phillips; Andreas G Katopodis; Rudolf O Duthaler; Mark S Cattral; William Wall; Anthony M Jevnikar; Michele Bailey; Gary A Levy; David R Grant
Improvement in human decay accelerating factor transgenic porcine kidney xenograft rejection with intravenous administration of gas914, a polymeric form of alphaGAL.
Transplantation 2003;75(1):10-9.
2003: Sylvie Lebel; Yoshiko Nakamachi; Alan W Hemming; Zul Verjee; M James Phillips; Katryn Furuya
Glycine conjugation of para-aminobenzoic acid (PABA): a pilot study of a novel prognostic test in acute liver failure in children.
Journal of pediatric gastroenterology and nutrition 2003;36(1):62-71.
2002: Anand Ghanekar; Ginette Lajoie; Yigang Luo; Hongji Yang; Jinsub Choi; Bertha Garcia; Edward H Cole; Paul D Greig; Mark S Cattral; M James Phillips; Carl J Cardella; Gary A Levy; Robert Zhong; David R Grant
Improvement in rejection of human decay accelerating factor transgenic pig-to-primate renal xenografts with administration of rabbit antithymocyte serum.
Transplantation 2002;74(1):28-35.
2002: Yang Wang; Derek C Newton; Tricia L Miller; Anouk-Martine Teichert; M James Phillips; Michail S Davidoff; Philip A Marsden
An alternative promoter of the human neuronal nitric oxide synthase gene is expressed specifically in Leydig cells.
The American journal of pathology 2002;160(1):369-80.
2001: Anand Ghanekar; Yigang Luo; Hongji Yang; Bertha Garcia; Patrick P W Luke; Subrata Chakrabarti; Ginette Lajoie; M James Phillips; Andreas G Katopodis; Mark S Cattral; William Wall; Anthony M Jevnikar; Michele Bailey; Gary A Levy; David R Grant; Robert Zhong
The alpha-Gal analog GAS914 ameliorates delayed rejection of hDAF transgenic pig-to-baboon renal xenografts.
Transplantation proceedings 2001;33(7-8):3853-4.
2001: Anand Ghanekar; Ginette Lajoie; Yigang Luo; Hongji Yang; Jinsub Choi; Bertha Garcia; Paul D Greig; Mark S Cattral; Edward H Cole; M James Phillips; Carl J Cardella; Gary A Levy; Robert Zhong; David R Grant
Treatment with rabbit antithymocyte serum permits a cyclophosphamide-free approach to prevention of hDAF transgenic porcine kidney xenograft rejection in baboons.
Transplantation proceedings 2001;33(7-8):3849-50.
2001: Gary A Levy; Anand Ghanekar; Michael Mendicino; M James Phillips; David R Grant
The present status of xenotransplantation.
Transplantation proceedings 2001;33(7-8):3050-2.
2000: Sandro B Rizoli; Ori D Rotstein; Jean Parodo; M James Phillips; Andras Kapus
Hypertonic inhibition of exocytosis in neutrophils: central role for osmotic actin skeleton remodeling.
American journal of physiology. Cell physiology 2000;279(3):C619-33.
2000: Gary A Levy; Mingyao Liu; J Ding; S Yuwaraj; Julian L Leibowitz; Philip A Marsden; Qin Ning; A Kovalinka; M James Phillips
Molecular and functional analysis of the human prothrombinase gene (HFGL2) and its role in viral hepatitis.
The American journal of pathology 2000;156(4):1217-25.
2000: Anouk-Martine Teichert; Tricia L Miller; Sharon C Tai; Yanchun Wang; X Bei; Gregory Robb; M James Phillips; Philip A Marsden
In vivo expression profile of an endothelial nitric oxide synthase promoter-reporter transgene.
American journal of physiology. Heart and circulatory physiology 2000;278(4):H1352-61.
1999: Qin Ning; Mingyao Liu; P Kongkham; M M Lai; Philip A Marsden; J Tseng; B Pereira; M Belyavskyi; Julian L Leibowitz; M James Phillips; Gary Levy
The nucleocapsid protein of murine hepatitis virus type 3 induces transcription of the novel fgl2 prothrombinase gene.
The Journal of biological chemistry 1999;274(15):9930-6.
1998: M Pope; Philip A Marsden; Edward Cole; S Sloan; Laisum Fung; Qin Ning; Jinwen Ding; Julian L Leibowitz; M James Phillips; Gary A Levy
Resistance to murine hepatitis virus strain 3 is dependent on production of nitric oxide.
Journal of virology 1998;72(9):7084-90.
1998: Qin Ning; D Brown; Jean Parodo; Mark S Cattral; Reginald Gorczynski; Edward Cole; Laisum Fung; Jinwen Ding; Ming Feng Liu; Ori D Rotstein; M James Phillips; Gary Levy
Ribavirin inhibits viral-induced macrophage production of TNF, IL-1, the procoagulant fgl2 prothrombinase and preserves Th1 cytokine production but inhibits Th2 cytokine response.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3487-93.
1998: Jinwen Ding; Qin Ning; Ming Feng Liu; A Lai; Kevork M Peltekian; Laisum Fung; C Holloway; H Yeger; M James Phillips; Gary A Levy
Expression of the fgl2 and its protein product (prothrombinase) in tissues during murine hepatitis virus strain-3 (MHV-3) infection.
Advances in experimental medicine and biology 1998;440():609-18.
1997: Jinwen Ding; Qin Ning; Ming Feng Liu; A Lai; Julian L Leibowitz; Kevork M Peltekian; Edward H Cole; Laisum Fung; C Holloway; Philip A Marsden; H Yeger; M James Phillips; Gary A Levy
Fulminant hepatic failure in murine hepatitis virus strain 3 infection: tissue-specific expression of a novel fgl2 prothrombinase.
Journal of virology 1997;71(12):9223-30.
1997: S W Chung; Paul D Greig; Mark S Cattral; Bryce R Taylor; P A Sheiner; Ian Wanless; R Cameron; M James Phillips; Laurie Blendis; Bernard Langer; Gary A Levy
Evaluation of liver transplantation for high-risk indications.
The British journal of surgery 1997;84(2):189-95.
1996: R J Fingerote; Michael M Abecassis; M James Phillips; Y S Rao; Edward H Cole; Julian L Leibowitz; Gary A Levy
Loss of resistance to murine hepatitis virus strain 3 infection after treatment with corticosteroids is associated with induction of macrophage procoagulant activity.
Journal of virology 1996;70(7):4275-82.
1994: M Elkashab; M Reizig; Paul D Greig; R Cameron; M James Phillips; S Chung; Mark S Cattral; Gary Levy
Incidence and patterns of rejection using different induction therapies in liver transplant recipients.
Transplantation proceedings 1994;26(5):2669-71.
1994: M Flowers; Averell Sherker; S B Sinclair; Paul D Greig; R Cameron; M James Phillips; Laurie Blendis; Stephen W Chung; Gary A Levy
Prostaglandin E in the treatment of recurrent hepatitis B infection after orthotopic liver transplantation.
Transplantation 1994;58(2):183-92.
1993: B W Donaldson; R Gopinath; Ian Wanless; M James Phillips; R Cameron; E A Roberts; Paul D Greig; Gary Levy; L M Blendis
The role of transjugular liver biopsy in fulminant liver failure: relation to other prognostic indicators.
Hepatology (Baltimore, Md.) 1993;18(6):1370-6.
1992: C Li; Laisum Fung; S Chung; Andrew R Crow; N Myers-Mason; M James Phillips; Julian L Leibowitz; Edward Cole; Clifford A Ottaway; Gary Levy
Monoclonal antiprothrombinase (3D4.3) prevents mortality from murine hepatitis virus (MHV-3) infection.
The Journal of experimental medicine 1992;176(3):689-97.
1989: S B Sinclair; Paul D Greig; L M Blendis; Michael M Abecassis; E A Roberts; M James Phillips; R Cameron; Gary A Levy
Biochemical and clinical response of fulminant viral hepatitis to administration of prostaglandin E. A preliminary report.
The Journal of clinical investigation 1989;84(4):1063-9.
1989: S Gallinger; Paul D Greig; Gary Levy; L M Blendis; E A Roberts; Riccardo A Superina; B R Taylor; Steven M Strasberg; M James Phillips; B Langer
Liver transplantation for acute and subacute fulminant hepatic failure.
Transplantation proceedings 1989;21(1 Pt 2):2435-8.
1989: Paul D Greig; Gary Levy; Riccardo A Superina; Steven M Strasberg; B R Taylor; L M Blendis; R Cameron; M James Phillips; B Langer
Antilymphoblast globulin (ALG) as initial prophylaxis against rejection following liver transplantation.
Transplantation proceedings 1989;21(1 Pt 2):2244-6.
1988: Tai-Wing Wu; J X Au; Paul D Greig; Steven M Strasberg; M Ettles; Michael M Abecassis; Riccardo A Superina; B Langer; Laurie Blendis; M James Phillips
Conjugated and delta bilirubin determinations in early liver allograft rejection.
Transplantation proceedings 1988;20(3 Suppl 3):383-90.