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Simon Phillips

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X Ray Crystallography

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TOP 3
Robert J Ford; Arwen R Pearson; Simon E V Phillips; Neil A Ranson; Saskia E Bakker; Amy M Barker; Robert H Coutts; Peter G Stockley
Sequence-specific, RNA-protein interactions overcome electrostatic barriers preventing assembly of satellite tobacco necrosis virus coat protein.
Yonca Yuzugullu; Ufuk Bakir; Zumrut B Ogel; Arwen R Pearson; Simon E V Phillips; Mark A Smith; Didem Sutay Kocabas; Chi H Trinh; Michael J McPherson
Structure, recombinant expression and mutagenesis studies of the catalase with oxidase activity from Scytalidium thermophilum.
David H J Bunka; Eric C Dykeman; Robert J Ford; Claire L Lane; Stephen W Lane; Simon E V Phillips; Amy M Barker; Reidun Twarock; Peter G Stockley
Degenerate RNA packaging signals in the genome of Satellite Tobacco Necrosis Virus: implications for the assembly of a T=1 capsid.

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2013: Robert J Ford; Arwen R Pearson; Simon E V Phillips; Neil A Ranson; Saskia E Bakker; Amy M Barker; Robert H Coutts; Peter G Stockley
Sequence-specific, RNA-protein interactions overcome electrostatic barriers preventing assembly of satellite tobacco necrosis virus coat protein.
Journal of molecular biology 2013;425(6):1050-64.
2013: Yonca Yuzugullu; Ufuk Bakir; Zumrut B Ogel; Arwen R Pearson; Simon E V Phillips; Mark A Smith; Didem Sutay Kocabas; Chi H Trinh; Michael J McPherson
Structure, recombinant expression and mutagenesis studies of the catalase with oxidase activity from Scytalidium thermophilum.
Acta crystallographica. Section D, Biological crystallography 2013;69(Pt 3):398-408.
2011: David H J Bunka; Eric C Dykeman; Robert J Ford; Claire L Lane; Stephen W Lane; Simon E V Phillips; Amy M Barker; Reidun Twarock; Peter G Stockley
Degenerate RNA packaging signals in the genome of Satellite Tobacco Necrosis Virus: implications for the assembly of a T=1 capsid.
Journal of molecular biology 2011;413(1):51-65.
2011: Stephen W Lane; Caitriona A Dennis; Claire L Lane; Pierre J Rizkallah; Peter G Stockley; Chi H Trinh; Simon E V Phillips
Construction and crystal structure of recombinant STNV capsids.
Journal of molecular biology 2011;413(1):41-50.
2011: Victoria L Green; Raymond J Owens; Simon E V Phillips; Anil Verma; Stephen B Carr
Structure of New Delhi metallo-β-lactamase 1 (NDM-1).
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 10):1160-4.
2011: Christian R P Kurtis; Thembaninkosi G Gaule; Peter F Knowles; Mark R Parsons; Simon E V Phillips; Michael J McPherson
Tyrosine 381 in E. coli copper amine oxidase influences substrate specificity.
Journal of neural transmission (Vienna, Austria : 1996) 2011;118(7):1043-53.
2011: Tomoyuki Tanaka; Helen Sewell; Simon Waters; Simon E V Phillips; Terence H Rabbitts
Single domain intracellular antibodies from diverse libraries: emphasizing dual functions of LMO2 protein interactions using a single VH domain.
The Journal of biological chemistry 2011;286(5):3707-16.
2010: Ivan Campeotto; Amanda H Bolt; Thomas A Harman; Caitriona Dennis; Chi H Trinh; Simon E V Phillips; Adam Nelson; Arwen R Pearson; Alan Berry
Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution.
Journal of molecular biology 2010;404(1):56-69.
2010: Mark A Smith; Pascale Pirrat; Arwen R Pearson; Christian R P Kurtis; Chi H Trinh; Thembaninkosi G Gaule; Peter F Knowles; Simon E V Phillips; Michael J McPherson
Exploring the roles of the metal ions in Escherichia coli copper amine oxidase.
Biochemistry 2010;49(6):1268-80.
2009: Ivan Campeotto; Stephen B Carr; Chi H Trinh; Adam S Nelson; Alan Berry; Simon E V Phillips; Arwen R Pearson
Structure of an Escherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 angstrom resolution.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 11):1088-90.
2009: Didem Sutay Kocabas; Arwen R Pearson; Simon E V Phillips; Ufuk Bakir; Zumrut B Ogel; Michael J McPherson; Chi H Trinh
Crystallization and preliminary X-ray analysis of a bifunctional catalase-phenol oxidase from Scytalidium thermophilum.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 5):486-8.
2009: Vasiliki E Fadouloglou; Marina N Bastaki; Alison E Ashcroft; Simon E V Phillips; Nickolas J Panopoulos; Nicholas M Glykos; Michael Kokkinidis
On the quaternary association of the type III secretion system HrcQB-C protein: experimental evidence differentiates among the various oligomerization models.
Journal of structural biology 2009;166(2):214-25.
2009: Chi H Trinh; Aruna Asipu; David T Bonthron; Simon E V Phillips
Structures of alternatively spliced isoforms of human ketohexokinase.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 3):201-11.
2008: Chi H Trinh; Thérèse Hunter; Emma E Stewart; Simon E V Phillips; Gary J Hunter
Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 12):1110-4.
2008: Pascale Pirrat; Mark A Smith; Arwen R Pearson; Michael J McPherson; Simon E V Phillips
Structure of a xenon derivative of Escherichia coli copper amine oxidase: confirmation of the proposed oxygen-entry pathway.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 12):1105-9.
2008: Xiaobing Xia; Vincent Postis; Moazur Rahman; Gareth S A Wright; Peter C J Roach; Sarah E Deacon; Jean C Ingram; Peter J F Henderson; John B C Findlay; Simon E V Phillips; Michael J McPherson; Stephen A Baldwin
Investigation of the structure and function of a Shewanella oneidensis arsenical-resistance family transporter.
Molecular membrane biology 2008;25(8):691-705.
2008: Sarah E Deacon; Peter C J Roach; Vincent Postis; Gareth S A Wright; Xiaobing Xia; Simon E V Phillips; J Paul Knox; Peter J F Henderson; Michael J McPherson; Stephen A Baldwin
Reliable scale-up of membrane protein over-expression by bacterial auto-induction: from microwell plates to pilot scale fermentations.
Molecular membrane biology 2008;25(8):588-98.
2008: Vincent Postis; Sarah E Deacon; Peter C J Roach; Gareth S A Wright; Xiaobing Xia; Jean C Ingram; Jonathan M Hadden; Peter J F Henderson; Simon E V Phillips; Michael J McPherson; Stephen A Baldwin
A high-throughput assay of membrane protein stability.
Molecular membrane biology 2008;25(8):617-24.
2008: Melanie S Rogers; Ramón Hurtado-Guerrero; Susan J Firbank; Malcolm A Halcrow; David M Dooley; Simon E V Phillips; Peter F Knowles; Michael J McPherson
Cross-link formation of the cysteine 228-tyrosine 272 catalytic cofactor of galactose oxidase does not require dioxygen.
Biochemistry 2008;47(39):10428-39.
2008: Sandeep Uppal; Christine P Diggle; Ian Carr; Colin W G Fishwick; Mushtaq Ahmed; Gamal H Ibrahim; Philip S Helliwell; Anna Latos-Bieleńska; Simon E V Phillips; Alexander F Markham; Christopher P Bennett; David T Bonthron
Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy.
Nature genetics 2008;40(6):789-93.
2008: Didem Sutay Kocabas; Ufuk Bakir; Simon E V Phillips; Michael J McPherson; Zumrut B Ogel
Purification, characterization, and identification of a novel bifunctional catalase-phenol oxidase from Scytalidium thermophilum.
Applied microbiology and biotechnology 2008;79(3):407-15.
2008: James A Garnett; Ferenc Marincs; Simon Baumberg; Peter G Stockley; Simon E V Phillips
Structure and function of the arginine repressor-operator complex from Bacillus subtilis.
Journal of molecular biology 2008;379(2):284-98.
2008: Colin J Dunsmore; Keith Miller; Katy L Blake; Simon G Patching; Peter J F Henderson; James A Garnett; William Stubbings; Simon E V Phillips; Deborah Palestrant; Joseph De Los Angeles; Jennifer A Leeds; Ian Chopra; Colin W G Fishwick
2-Aminotetralones: novel inhibitors of MurA and MurZ.
Bioorganic & medicinal chemistry letters 2008;18(5):1730-4.
2007: James A Garnett; Simon Baumberg; Peter G Stockley; Simon E V Phillips
Structure of the C-terminal effector-binding domain of AhrC bound to its corepressor L-arginine.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 11):918-21.
2007: James A Garnett; Simon Baumberg; Peter G Stockley; Simon E V Phillips
A high-resolution structure of the DNA-binding domain of AhrC, the arginine repressor/activator protein from Bacillus subtilis.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 11):914-7.
2007: Jonathan M Hadden; Anne-Cécile Déclais; Stephen B Carr; David M J Lilley; Simon E V Phillips
The structural basis of Holliday junction resolution by T7 endonuclease I.
Nature 2007;449(7162):621-4.
2007: Neil R Syme; Caitriona Dennis; Simon E V Phillips; Steve W Homans
Origin of heat capacity changes in a "nonclassical" hydrophobic interaction.
Chembiochem : a European journal of chemical biology 2007;8(13):1509-11.
2007: Melanie S Rogers; Ejan M Tyler; Nana Akyumani; christian kurtis; R Kate Spooner; Sarah E Deacon; Sarita Tamber; Susan J Firbank; Khaled Mahmoud; Peter F Knowles; Simon E V Phillips; Michael J McPherson; David M Dooley
The stacking tryptophan of galactose oxidase: a second-coordination sphere residue that has profound effects on tyrosyl radical behavior and enzyme catalysis.
Biochemistry 2007;46(15):4606-18.
2007: Chi H Trinh; Yang Liu; Simon E V Phillips; Mary K Phillips-Jones
Structure of the response regulator VicR DNA-binding domain.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 2):266-9.
2006: Stephen B Carr; George Makris; Simon E V Phillips; Christopher D Thomas
Crystallization and preliminary X-ray diffraction analysis of two N-terminal fragments of the DNA-cleavage domain of topoisomerase IV from Staphylococcus aureus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 11):1164-7.
2006: Simon E V Phillips
Turning up the HEAT on translation.
Structure (London, England : 1993) 2006;14(5):806-7.
2006: Wilf T Horn; Kaspars Tars; Elin Grahn; Charlotte Helgstrand; Andrew J Baron; Hugo Lago; Chris J Adams; David S Peabody; Simon E V Phillips; Nicola J Stonehouse; Lars Liljas; Peter G Stockley
Structural basis of RNA binding discrimination between bacteriophages Qbeta and MS2.
Structure (London, England : 1993) 2006;14(3):487-95.
2006: Richard J Bingham; Vincent Dive; Simon E V Phillips; Alan D Shirras; R Elwyn Isaac
Structural diversity of angiotensin-converting enzyme.
The FEBS journal 2006;273(2):362-73.
2006: Jane E Murphy; Daryl Tacon; Philip R Tedbury; Jonathan M Hadden; Stuart Knowling; Tatsuya Sawamura; Michelle Peckham; Simon E V Phillips; John H Walker; Sreenivasan Ponnambalam
LOX-1 scavenger receptor mediates calcium-dependent recognition of phosphatidylserine and apoptotic cells.
The Biochemical journal 2006;393(Pt 1):107-15.
2005: Richard Malham; Sarah Johnstone; Richard J Bingham; Elizabeth Barratt; Simon E V Phillips; Charles A Laughton; Steve W Homans
Strong solute-solute dispersive interactions in a protein-ligand complex.
Journal of the American Chemical Society 2005;127(48):17061-7.
2005: Elizabeth Barratt; Richard J Bingham; Daniel Jon Warner; Charles A Laughton; Simon E V Phillips; Steve W Homans
Van der Waals interactions dominate ligand-protein association in a protein binding site occluded from solvent water.
Journal of the American Chemical Society 2005;127(33):11827-34.
2005: Minae Mure; christian kurtis; Doreen E Brown; Melanie S Rogers; Winston S Tambyrajah; Colin G Saysell; Carrie M Wilmot; Simon E V Phillips; Peter F Knowles; David M Dooley; Michael J McPherson
Active site rearrangement of the 2-hydrazinopyridine adduct in Escherichia coli amine oxidase to an azo copper(II) chelate form: a key role for tyrosine 369 in controlling the mobility of the TPQ-2HP adduct.
Biochemistry 2005;44(5):1583-94.
2005: Minae Mure; Doreen E Brown; Colin G Saysell; Melanie S Rogers; Carrie M Wilmot; christian kurtis; Michael J McPherson; Simon E V Phillips; Peter F Knowles; David M Dooley
Role of the interactions between the active site base and the substrate Schiff base in amine oxidase catalysis. Evidence from structural and spectroscopic studies of the 2-hydrazinopyridine adduct of Escherichia coli amine oxidase.
Biochemistry 2005;44(5):1568-82.
2004: Wilf T Horn; Máire A Convery; Nicola J Stonehouse; Chris J Adams; Lars Liljas; Simon E V Phillips; Peter G Stockley
The crystal structure of a high affinity RNA stem-loop complexed with the bacteriophage MS2 capsid: further challenges in the modeling of ligand-RNA interactions.
RNA (New York, N.Y.) 2004;10(11):1776-82.
2004: Carrie M Wilmot; Colin G Saysell; Aidan Blessington; Danyl A Conn; christian kurtis; Michael J McPherson; Peter F Knowles; Simon E V Phillips
Medical implications from the crystal structure of a copper-containing amine oxidase complexed with the antidepressant drug tranylcypromine.
FEBS letters 2004;576(3):301-5.
2004: Sarah E Deacon; Khaled Mahmoud; R Kate Spooner; Susan J Firbank; Peter F Knowles; Simon E V Phillips; Michael J McPherson
Enhanced fructose oxidase activity in a galactose oxidase variant.
Chembiochem : a European journal of chemical biology 2004;5(7):972-9.
2004: Richard J Bingham; John B C Findlay; Shih-Yang Hsieh; Arnout P Kalverda; Alexandra Kjellberg; Chiara Perazzolo; Simon E V Phillips; Kothandaraman Seshadri; Chi H Trinh; W Bruce Turnbull; Geoffrey Bodenhausen; Steve W Homans
Thermodynamics of binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the major urinary protein.
Journal of the American Chemical Society 2004;126(6):1675-81.
2004: D Wilkinson; N Akumanyi; R Hurtado-Guerrero; H Dawkes; Peter F Knowles; Simon E V Phillips; Michael J McPherson
Structural and kinetic studies of a series of mutants of galactose oxidase identified by directed evolution.
Protein engineering, design & selection : PEDS 2004;17(2):141-8.
2004: Vasiliki E Fadouloglou; Anastasia P Tampakaki; Nicholas M Glykos; Marina N Bastaki; Jonathan M Hadden; Simon E V Phillips; Nickolas J Panopoulos; Michael Kokkinidis
Structure of HrcQB-C, a conserved component of the bacterial type III secretion systems.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):70-5.
2004: Susan J Firbank; Melanie Rogers; Ramon Hurtado Guerrero; David M Dooley; Malcolm A Halcrow; Simon E V Phillips; Peter F Knowles; Michael J McPherson
Cofactor processing in galactose oxidase.
Biochemical Society symposium 2004;(71):15-25.
2003: Susan J Firbank; M Rogers; R Hurtado-Guerrero; David M Dooley; Malcolm A Halcrow; Simon E V Phillips; Peter F Knowles; Michael J McPherson
Cofactor processing in galactose oxidase.
Biochemical Society transactions 2003;31(Pt 3):506-9.
2003: James R Horton; Julieanne M Bostock; Ian Chopra; Lars Hesse; Simon E V Phillips; David J Adams; A Peter Johnson; Colin W G Fishwick
Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD.
Bioorganic & medicinal chemistry letters 2003;13(9):1557-60.
2003: Anne-Cécile Déclais; Jonathan M Fogg; Alasdair D J Freeman; Franck Coste; Jonathan M Hadden; Simon E V Phillips; David M J Lilley
The complex between a four-way DNA junction and T7 endonuclease I.
The EMBO journal 2003;22(6):1398-409.
2002: Colin G Saysell; Winston S Tambyrajah; Jeremy M Murray; Carrie M Wilmot; Simon E V Phillips; Michael J McPherson; Peter F Knowles
Probing the catalytic mechanism of Escherichia coli amine oxidase using mutational variants and a reversible inhibitor as a substrate analogue.
The Biochemical journal 2002;365(Pt 3):809-16.
2002: Chi H Trinh; David P Smith; Arnout P Kalverda; Simon E V Phillips; Sheena E Radford
Crystal structure of monomeric human beta-2-microglobulin reveals clues to its amyloidogenic properties.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):9771-6.
2002: Jonathan M Hadden; Anne-Cécile Déclais; Simon E V Phillips; David M J Lilley
Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I.
The EMBO journal 2002;21(13):3505-15.
2002: Yi-Yuan He; Colin W Garvie; stone elworthy; Iain W Manfield; Teresa McNally; Isobel D Lawrenson; Simon E V Phillips; Peter G Stockley
Structural and functional studies of an intermediate on the pathway to operator binding by Escherichia coli MetJ.
Journal of molecular biology 2002;320(1):39-53.
2002: Caitríona A Dennis C; Nicholas M Glykos; Mark R Parsons; Simon E V Phillips
The structure of AhrC, the arginine repressor/activator protein from Bacillus subtilis.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 3):421-30.
2002: Louisa Sheridan; Carrie M Wilmot; Karen D Cromie; Paul van der Logt; Simon E V Phillips
Crystallization and preliminary X-ray structure determination of jack bean urease with a bound antibody fragment.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 2):374-6.
2001: H C Dawkes; Simon E V Phillips
Copper amine oxidase: cunning cofactor and controversial copper.
Current opinion in structural biology 2001;11(6):666-73.
2001: Susan J Firbank; Melanie S Rogers; Carrie M Wilmot; David M Dooley; Malcolm A Halcrow; Peter F Knowles; Michael J McPherson; Simon E V Phillips
Crystal structure of the precursor of galactose oxidase: an unusual self-processing enzyme.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):12932-7.
2001: Jeremy M Murray; christian kurtis; Winston S Tambyrajah; Colin G Saysell; Carrie M Wilmot; Mark R Parsons; Simon E V Phillips; Peter F Knowles; Michael J McPherson
Conserved tyrosine-369 in the active site of Escherichia coli copper amine oxidase is not essential.
Biochemistry 2001;40(43):12808-18.
2001: Anne-Cécile Déclais; Jonathan M Hadden; Simon E V Phillips; David M J Lilley
The active site of the junction-resolving enzyme T7 endonuclease I.
Journal of molecular biology 2001;307(4):1145-58.
2001: Jonathan M Hadden; Máire A Convery; Anne-Cécile Déclais; David M J Lilley; Simon E V Phillips
Crystal structure of the Holliday junction resolving enzyme T7 endonuclease I.
Nature structural biology 2001;8(1):62-7.
2000: C W Garvie; Simon E V Phillips
Direct and indirect readout in mutant Met repressor-operator complexes.
Structure (London, England : 1993) 2000;8(9):905-14.
1999: Carrie M Wilmot; Janos Hajdu; Michael J McPherson; Peter F Knowles; Simon E V Phillips
Visualization of dioxygen bound to copper during enzyme catalysis.
Science (New York, N.Y.) 1999;286(5445):1724-8.
1999: Daniel J Rigden; Simon E V Phillips; Paul A M Michels; Linda A Fothergill-Gilmore
The structure of pyruvate kinase from Leishmania mexicana reveals details of the allosteric transition and unusual effector specificity.
Journal of molecular biology 1999;291(3):615-35.
1999: Jeremy M Murray; Colin G Saysell; Carrie M Wilmot; Winston S Tambyrajah; J Jaeger; Peter F Knowles; Simon E V Phillips; Michael J McPherson
The active site base controls cofactor reactivity in Escherichia coli amine oxidase: x-ray crystallographic studies with mutational variants.
Biochemistry 1999;38(26):8217-27.
1999: Daniel J Rigden; RA Walter; Simon E V Phillips; Linda A Fothergill-Gilmore
Polyanionic inhibitors of phosphoglycerate mutase: combined structural and biochemical analysis.
Journal of molecular biology 1999;289(4):691-9.
1999: D E Klimenko; Máire A Convery; S Rowsell; C D Thomas; Simon E V Phillips
Crystallization and preliminary X-ray crystallographic studies of RepDC, a hybrid rolling-circle plasmid replication initiator protein.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 5):1076-8.
1999: Panos Soultanas; Mark S Dillingham; F Papadopoulos; Simon E V Phillips; Christopher D Thomas; Dale B Wigley
Plasmid replication initiator protein RepD increases the processivity of PcrA DNA helicase.
Nucleic acids research 1999;27(6):1421-8.
1999: Daniel J Rigden; RA Walter; Simon E V Phillips; Linda A Fothergill-Gilmore
Sulphate ions observed in the 2.12 A structure of a new crystal form of S. cerevisiae phosphoglycerate mutase provide insights into understanding the catalytic mechanism.
Journal of molecular biology 1999;286(5):1507-17.
1999: H Song; Mark R Parsons; S Rowsell; G Leonard; Simon E V Phillips
Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 A resolution.
Journal of molecular biology 1999;285(3):1245-56.
1998: S Rowsell; Nicola J Stonehouse; Máire A Convery; Chris J Adams; Andrew D Ellington; I Hirao; David S Peabody; Peter G Stockley; Simon E V Phillips
Crystal structures of a series of RNA aptamers complexed to the same protein target.
Nature structural biology 1998;5(11):970-5.
1998: M Newman; K Lunnen; G Wilson; J Greci; Schildkraut Ira; Simon E V Phillips
Crystal structure of restriction endonuclease BglI bound to its interrupted DNA recognition sequence.
The EMBO journal 1998;17(18):5466-76.
1998: Nicholas M Glykos; Andreas Holzenburg; Simon E V Phillips
Low-resolution structural characterization of the arginine repressor/activator from Bacillus subtilis: a combined X-ray crystallographic and electron microscopical approach.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 2):215-25.
1998: Daniel J Rigden; D Alexeev; Simon E V Phillips; Linda A Fothergill-Gilmore
The 2.3 A X-ray crystal structure of S. cerevisiae phosphoglycerate mutase.
Journal of molecular biology 1998;276(2):449-59.
1998: Máire A Convery; S Rowsell; Nicola J Stonehouse; Andrew D Ellington; I Hirao; James B Murray; David S Peabody; Simon E V Phillips; Peter G Stockley
Crystal structure of an RNA aptamer-protein complex at 2.8 A resolution.
Nature structural biology 1998;5(2):133-9.
1997: Mark Griffiths; Sylvia Y M Yao; Fatima Abidi; Simon E V Phillips; Carol E Cass; James D Young; Stephen A Baldwin
Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta.
The Biochemical journal 1997;328 ( Pt 3)():739-43.
1997: Chi H Trinh; S D Hemmington; M E Verhoeyen; Simon E V Phillips
Antibody fragment Fv4155 bound to two closely related steroid hormones: the structural basis of fine specificity.
Structure (London, England : 1993) 1997;5(7):937-48.
1997: Carrie M Wilmot; Jeremy M Murray; Gwen Y Alton; Mark R Parsons; Máire A Convery; V Blakeley; A S Corner; Monica Palcic; Peter F Knowles; Michael J McPherson; Simon E V Phillips
Catalytic mechanism of the quinoenzyme amine oxidase from Escherichia coli: exploring the reductive half-reaction.
Biochemistry 1997;36(7):1608-20.
1996: C M Wild; Teresa McNally; Simon E V Phillips; Peter G Stockley
Effects of systematic variation of the minimal Escherichia coli met consensus operator site: in vivo and in vitro met repressor binding.
Molecular microbiology 1996;21(6):1125-35.
1996: H Song; Simon E V Phillips; Mark R Parsons; R Maas
Crystallization and preliminary crystallographic analysis of RepA1, a replication control protein of the RepFIC replicon of enterotoxin plasmid EntP307.
Proteins 1996;25(1):137-8.
1996: Simon E V Phillips; P G Stockley
Structure and function of Escherichia coli met repressor: similarities and contrasts with trp repressor.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1996;351(1339):527-35.
1996: Naomi E Chayen; Elspeth J Gordon; Simon E V Phillips; E E Saridakis; Peter F Zagalsky
Crystallization and initial X-ray analysis of beta-crustacyanin, the dimer of apoproteins A2 and C1, each with a bound astaxanthin molecule.
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 2):409-10.
1995: Mark R Parsons; Máire A Convery; Carrie M Wilmot; K D Yadav; V Blakeley; A S Corner; Simon E V Phillips; Michael J McPherson; Peter F Knowles
Crystal structure of a quinoenzyme: copper amine oxidase of Escherichia coli at 2 A resolution.
Structure (London, England : 1993) 1995;3(11):1171-84.
1995: M P Reynolds; A J Baron; Carrie M Wilmot; Simon E V Phillips; Peter F Knowles; Michael J McPherson
Tyrosine 495 is a key residue in the active site of galactose oxidase.
Biochemical Society transactions 1995;23(4):510S.
1995: N Ito; Peter F Knowles; Simon E V Phillips
X-ray crystallographic studies of cofactors in galactose oxidase.
Methods in enzymology 1995;258():235-62.
1994: A J Baron; C Stevens; Carrie M Wilmot; K D Seneviratne; V Blakeley; David M Dooley; Simon E V Phillips; Peter F Knowles; Michael J McPherson
Structure and mechanism of galactose oxidase. The free radical site.
The Journal of biological chemistry 1994;269(40):25095-105.
1994: N Ito; Simon E V Phillips; K D Yadav; Peter F Knowles
Crystal structure of a free radical enzyme, galactose oxidase.
Journal of molecular biology 1994;238(5):794-814.
1994: K Phillips; Simon E V Phillips
Electrostatic activation of Escherichia coli methionine repressor.
Structure (London, England : 1993) 1994;2(4):309-16.
1994: Simon E V Phillips
Built by association: structure and function of helix-loop-helix DNA-binding proteins.
Structure (London, England : 1993) 1994;2(1):1-4.
1994: Simon E V Phillips
The beta-ribbon DNA recognition motif.
Annual review of biophysics and biomolecular structure 1994;23():671-701.
1993: Michael J McPherson; C Stevens; A J Baron; Z B Ogel; K Seneviratne; Carrie M Wilmot; N Ito; I Brocklebank; Simon E V Phillips; Peter F Knowles
Galactose oxidase: molecular analysis and mutagenesis studies.
Biochemical Society transactions 1993;21 ( Pt 3)(3):752-6.
1993: A J Baron; C Stevens; Carrie M Wilmot; Peter F Knowles; Simon E V Phillips; Michael J McPherson
Preliminary studies of two active site mutants of galactose oxidase.
Biochemical Society transactions 1993;21 ( Pt 3)(3):319S.
1992: Zsolt Bocskei; C R Groom; Darren R Flower; C E Wright; Simon E V Phillips; Andrea Cavaggioni; John B C Findlay; A C North
Pheromone binding to two rodent urinary proteins revealed by X-ray crystallography.
Nature 1992;360(6400):186-8.
1992: Y Y He; Teresa McNally; I Manfield; O Navratil; I G Old; Simon E V Phillips; Isabelle Saint-Girons; Peter G Stockley
Probing met repressor-operator recognition in solution.
Nature 1992;359(6394):431-3.
1992: W S Somers; Simon E V Phillips
Crystal structure of the met repressor-operator complex at 2.8 A resolution reveals DNA recognition by beta-strands.
Nature 1992;359(6394):387-93.
1992: C E Wright; J B Rafferty; Darren R Flower; C R Groom; John B C Findlay; A C North; Simon E V Phillips; Peter F Zagalsky
Crystallization and initial X-ray analysis of the C2-subunit of crustacyanin.
Journal of molecular biology 1992;224(1):283-4.
1992: N Ito; Simon E V Phillips; C Stevens; Z B Ogel; Michael J McPherson; J N Keen; K D Yadav; Peter F Knowles
Three-dimensional structure of galactose oxidase: an enzyme with a built-in secondary cofactor.
Faraday discussions 1992;(93):75-84.
1991: T O Fischmann; Graham A Bentley; T N Bhat; G Boulot; Roy A Mariuzza; Simon E V Phillips; D Tello; Roberto Poljak
Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-A resolution.
The Journal of biological chemistry 1991;266(20):12915-20.
1991: Zsolt Bocskei; John B C Findlay; A C North; Simon E V Phillips; W S Somers; C E Wright; C Lionetti; Roberto Tirindelli; Andrea Cavaggioni
Crystallization of and preliminary X-ray data for the mouse major urinary protein and rat alpha-2u globulin.
Journal of molecular biology 1991;218(4):699-701.
1991: N Ito; Simon E V Phillips; C Stevens; Z B Ogel; Michael J McPherson; J N Keen; K D Yadav; Peter F Knowles
Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase.
Nature 1991;350(6313):87-90.
1991: I G Old; Simon E V Phillips; P G Stockley; Isabelle Saint-Girons
Regulation of methionine biosynthesis in the Enterobacteriaceae.
Progress in biophysics and molecular biology 1991;56(3):145-85.
1990: N Ito; J N Keen; Peter F Knowles; Michael J McPherson; Simon E V Phillips; C Stevens; K D Yadav
Structural analysis of galactose oxidase.
Biochemical Society transactions 1990;18(5):931-2.
1990: C W Boys; Lloyd Czaplewski; Simon E V Phillips; Simon Baumberg; Peter G Stockley
Crystallization of the arginine-dependent repressor/activator AhrC from Bacillus subtilis.
Journal of molecular biology 1990;213(2):227-8.
1989: Simon E V Phillips; I Manfield; I Parsons; B E Davidson; J B Rafferty; W S Somers; D Margarita; G N Cohen; Isabelle Saint-Girons; Peter G Stockley
Cooperative tandem binding of met repressor of Escherichia coli.
Nature 1989;341(6244):711-5.
1989: J B Rafferty; W S Somers; Isabelle Saint-Girons; Simon E V Phillips
Three-dimensional crystal structures of Escherichia coli met repressor with and without corepressor.
Nature 1989;341(6244):705-10.
1988: J B Rafferty; Simon E V Phillips; C Rojas; G Boulot; Isabelle Saint-Girons; Y Guillou; G N Cohen
Crystallization of the met repressor from Escherichia coli.
Journal of molecular biology 1988;200(1):217-9.
1985: A G Amit; G Boulot; M B Comarmond; M Harper; Roy A Mariuzza; Simon E V Phillips; P Saludjian; Frederick A Saul; H Souchon; P Tougard
X-ray diffraction studies of an anti-azophenylarsonate antibody and of an antigen-antibody complex.
Annales de l'Institut Pasteur. Immunologie 1985;136C(1):121-9.