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Lorna Piazzi

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Stefano Rizzo; Manuela Bartolini; Luisa Ceccarini; Lorna Piazzi; Silvia Gobbi; Andrea Cavalli; Maurizio Recanatini; Vincenza Andrisano; Angela Rampa
Targeting Alzheimer's disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238.
Andrea Cavalli; Federica Lizzi; Salvatore Bongarzone; Federica Belluti; Lorna Piazzi; Maria Laura Bolognesi
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates.
Federica Belluti; Lorna Piazzi; Alessandra Bisi; Silvia Gobbi; Manuela Bartolini; Andrea Cavalli; Piero Valenti; Angela Rampa
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors.

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All Publications

2010: Stefano Rizzo; Manuela Bartolini; Luisa Ceccarini; Lorna Piazzi; Silvia Gobbi; Andrea Cavalli; Maurizio Recanatini; Vincenza Andrisano; Angela Rampa
Targeting Alzheimer's disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238.
Bioorganic & medicinal chemistry 2010;18(5):1749-60.
2010: Andrea Cavalli; Federica Lizzi; Salvatore Bongarzone; Federica Belluti; Lorna Piazzi; Maria Laura Bolognesi
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates.
FEMS immunology and medical microbiology 2010;58(1):51-60.
2009: Federica Belluti; Lorna Piazzi; Alessandra Bisi; Silvia Gobbi; Manuela Bartolini; Andrea Cavalli; Piero Valenti; Angela Rampa
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors.
European journal of medicinal chemistry 2009;44(3):1341-8.
2008: Lorna Piazzi; Andrea Cavalli; Francesco Colizzi; Federica Belluti; Manuela Bartolini; Francesca Mancini; Maurizio Recanatini; Vincenza Andrisano; Angela Rampa
Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds.
Bioorganic & medicinal chemistry letters 2008;18(1):423-6.
2007: Lorna Piazzi; Andrea Cavalli; Federica Belluti; Alessandra Bisi; Silvia Gobbi; Stefano Rizzo; Manuela Bartolini; Vincenza Andrisano; Maurizio Recanatini; Angela Rampa
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives.
Journal of medicinal chemistry 2007;50(17):4250-4.
2007: Silvia Gobbi; Andrea Cavalli; Matthias Negri; Katarzyna E Schewe; Federica Belluti; Lorna Piazzi; Rolf W Hartmann; Maurizio Recanatini; Alessandra Bisi
Imidazolylmethylbenzophenones as highly potent aromatase inhibitors.
Journal of medicinal chemistry 2007;50(15):3420-2.
2007: Lorna Piazzi; Federica Belluti; Alessandra Bisi; Silvia Gobbi; Stefano Rizzo; Manuela Bartolini; Vincenza Andrisano; Maurizio Recanatini; Angela Rampa
Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[omega-(benzylmethylamino)alkoxy]xanthen-9-ones.
Bioorganic & medicinal chemistry 2007;15(1):575-85.
2006: Silvia Gobbi; Andrea Cavalli; Angela Rampa; Federica Belluti; Lorna Piazzi; Anja Paluszcak; Rolf W Hartmann; Maurizio Recanatini; Alessandra Bisi
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme.
Journal of medicinal chemistry 2006;49(15):4777-80.
2006: Silvia Gobbi; Federica Belluti; Alessandra Bisi; Lorna Piazzi; Angela Rampa; Antonella Zampiron; Mariagnese Barbera; Anna Caputo; Maria Carrara
New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells.
Bioorganic & medicinal chemistry 2006;14(12):4101-9.
2006: Alessandra Bisi; Silvia Gobbi; Angela Rampa; Federica Belluti; Lorna Piazzi; Piero Valenti; Nora Gyemant; Joseph Molnár
New potent P-glycoprotein inhibitors carrying a polycyclic scaffold.
Journal of medicinal chemistry 2006;49(11):3049-51.
2005: Andrea Cavalli; Alessandra Bisi; Carlo Bertucci; Carlo Rosini; Anja Paluszcak; Silvia Gobbi; Egidio Giorgio; Angela Rampa; Federica Belluti; Lorna Piazzi; Piero Valenti; Rolf W Hartmann; Maurizio Recanatini
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach.
Journal of medicinal chemistry 2005;48(23):7282-9.
2005: Federica Belluti; Angela Rampa; Lorna Piazzi; Alessandra Bisi; Silvia Gobbi; Manuela Bartolini; Vincenza Andrisano; Andrea Cavalli; Maurizio Recanatini; Piero Valenti
Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation.
Journal of medicinal chemistry 2005;48(13):4444-56.
2005: Roberta Budriesi; Alessandra Bisi; Pierfranco Ioan; Angela Rampa; Silvia Gobbi; Federica Belluti; Lorna Piazzi; Piero Valenti; Alberto Chiarini
1,4-Dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety.
Bioorganic & medicinal chemistry 2005;13(10):3423-30.
2005: Maria Carrara; Antonella Zampiron; Mariagnese Barbera; Anna Caputo; Alessandra Bisi; Silvia Gobbi; Federica Belluti; Lorna Piazzi; Angela Rampa; Piero Valenti
Mono- or di-fluorinated analogues of flavone-8-acetic acid: synthesis and in vitro biological activity.
Anticancer research 2005;25(2A):1179-85.
2005: Angela Rampa; Alessandra Bisi; Federica Belluti; Silvia Gobbi; Lorna Piazzi; Piero Valenti; Antonella Zampiron; Anna Caputo; Katia Varani; Pier Andrea Borea; Maria Carrara
Homopterocarpanes as bridged triarylethylene analogues: synthesis and antagonistic effects in human MCF-7 breast cancer cells.
Farmaco (Società chimica italiana : 1989) 2005;60(2):135-47.
2003: Silvia Gobbi; Angela Rampa; Alessandra Bisi; Federica Belluti; Lorna Piazzi; Piero Valenti; Anna Caputo; Antonella Zampiron; Maria Carrara
Synthesis and biological evaluation of 3-alkoxy analogues of flavone-8-acetic acid.
Journal of medicinal chemistry 2003;46(17):3662-9.
2003: Lorna Piazzi; Angela Rampa; Alessandra Bisi; Silvia Gobbi; Federica Belluti; Andrea Cavalli; Manuela Bartolini; Vincenza Andrisano; Piero Valenti; Maurizio Recanatini
3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy.
Journal of medicinal chemistry 2003;46(12):2279-82.
2001: Angela Rampa; Lorna Piazzi; Federica Belluti; Silvia Gobbi; Alessandra Bisi; Manuela Bartolini; Vincenza Andrisano; Vanni Cavrini; Andrea Cavalli; Maurizio Recanatini; Piero Valenti
Acetylcholinesterase inhibitors: SAR and kinetic studies on omega-[N-methyl-N-(3-alkylcarbamoyloxyphenyl)methyl]aminoalkoxyaryl derivatives.
Journal of medicinal chemistry 2001;44(23):3810-20.
2000: Maurizio Recanatini; Andrea Cavalli; Federica Belluti; Lorna Piazzi; Angela Rampa; Alessandra Bisi; Silvia Gobbi; Piero Valenti; Vincenza Andrisano; Manuela Bartolini; Vanni Cavrini
SAR of 9-amino-1,2,3,4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues.
Journal of medicinal chemistry 2000;43(10):2007-18.