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Chantal Pichon

Research Profile

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TOP 3
Chantal Pichon; Patrick Midoux
Mannosylated and histidylated LPR technology for vaccination with tumor antigen mRNA.
Ludivine Billiet; Hervé Cheradame; Jean-Pierre Gomez; Philippe Guégan; Paul-Alain Jaffrès; Tony Le Gall; Pierre Lehn; Mathieu Mével; Thierry Benvegnu; Mathieu Berchel; Emilie Bertrand; Tristan Montier; Chantal Pichon; Bruno Pitard; Patrick Midoux
Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line.
Fabienne Godin; TK Hevor; Séverine Morisset-Lopez; Chantal Pichon; Béatrice Vallée; Sandrine Villette; Maryvonne Ardourel; Michel Doudeau; Hélène Bénédetti
A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line.

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All Publications

2013: Chantal Pichon; Patrick Midoux
Mannosylated and histidylated LPR technology for vaccination with tumor antigen mRNA.
Methods in molecular biology (Clifton, N.J.) 2013;969():247-74.
2012: Ludivine Billiet; Hervé Cheradame; Jean-Pierre Gomez; Philippe Guégan; Paul-Alain Jaffrès; Tony Le Gall; Pierre Lehn; Mathieu Mével; Thierry Benvegnu; Mathieu Berchel; Emilie Bertrand; Tristan Montier; Chantal Pichon; Bruno Pitard; Patrick Midoux
Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line.
Biomaterials 2012;33(10):2980-90.
2012: Fabienne Godin; TK Hevor; Séverine Morisset-Lopez; Chantal Pichon; Béatrice Vallée; Sandrine Villette; Maryvonne Ardourel; Michel Doudeau; Hélène Bénédetti
A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line.
Biochemical and biophysical research communications 2012;418(4):689-94.
2012: Federico Perche; Chantal Pichon; Mathieu Berchel; Paul-Alain Jaffrès; Olivier Lambert; Patrick Midoux
Gene transfer by histidylated lipopolyplexes: A dehydration method allowing preservation of their physicochemical parameters and transfection efficiency.
International journal of pharmaceutics 2012;423(1):144-50.
2012: Célia S Bonnet; Frédéric Buron; Fabien Caillé; Bohuslav Drahoš; Lothar Helm; Laurent Pellegatti; Stéphane Petoud; Chantal Pichon; Chad M Shade; Franck Suzenet; Sandrine Villette; Jian Zhang; Eva Tóth
Pyridine-based lanthanide complexes combining MRI and NIR luminescence activities.
Chemistry (Weinheim an der Bergstrasse, Germany) 2012;18(5):1419-31.
2011: Emilie Bertrand; Ludivine Billiet; Hervé Cheradame; Jean Pierre Gomez; Christine Gonçalves; Patrick Midoux; Chantal Pichon; Philippe Guégan
Histidinylated linear PEI: a new efficient non-toxic polymer for gene transfer.
Chemical communications (Cambridge, England) 2011;47(46):12547-9.
2011: Federico Perche; David Gosset; mathieu mével; Marie-Laure Miramon; Jean-Jacques Yaouanc; Chantal Pichon; Thierry Benvegnu; Paul-Alain Jaffrès; Patrick Midoux
Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes.
Journal of drug targeting 2011;19(5):315-25.
2010: Arnaud Suwalski; Hinda Dabboue; Anthony Delalande; Sabine F Bensamoun; Francis Canon; Patrick Midoux; Gérard Saillant; David Klatzmann; Jean-Paul Salvetat; Chantal Pichon
Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles.
Biomaterials 2010;31(19):5237-45.
2010: Anthony Delalande; Michel-Francis Bureau; Patrick Midoux; Ayache Bouakaz; Chantal Pichon
Ultrasound-assisted microbubbles gene transfer in tendons for gene therapy.
Ultrasonics 2010;50(2):269-72.
2010: Marie Breton; Jeanne Leblond; Johanne Seguin; Patrick Midoux; Daniel Scherman; Jean Herscovici; Chantal Pichon; Nathalie MIGNET
Comparative gene transfer between cationic and thiourea lipoplexes.
The journal of gene medicine 2010;12(1):45-54.
2009: Patrick Midoux; Chantal Pichon; Jean-Jacques Yaouanc; Paul-Alain Jaffrès
Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers.
British journal of pharmacology 2009;157(2):166-78.
2009: Christine Gonçalves; Marie-Yvonne Ardourel; Martine Decoville; Gilles Breuzard; Patrick Midoux; Brigitte Hartmann; Chantal Pichon
An optimized extended DNA kappa B site that enhances plasmid DNA nuclear import and gene expression.
The journal of gene medicine 2009;11(5):401-11.
2009: Corinne Buré; Régine Maget; Agnès F Delmas; Chantal Pichon; Patrick Midoux
Histidine-rich peptide: evidence for a single zinc-binding site on H5WYG peptide that promotes membrane fusion at neutral pH.
Journal of mass spectrometry : JMS 2009;44(1):81-9.
2008: Patrick Midoux; Gilles Breuzard; Jean Pierre Gomez; Chantal Pichon
Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes.
Current gene therapy 2008;8(5):335-52.
2008: mathieu mével; Cécile Neveu; Cristine Gonçalves; Jean-Jacques Yaouanc; Chantal Pichon; Paul-Alain Jaffrès; Patrick Midoux
Novel neutral imidazole-lipophosphoramides for transfection assays.
Chemical communications (Cambridge, England) 2008;(27):3124-6.
2008: Gilles Breuzard; Magdalena Tertil; Christine Gonçalves; Hervé Cheradame; Philippe Géguan; Chantal Pichon; Patrick Midoux
Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging.
Nucleic acids research 2008;36(12):e71.
2008: mathieu mével; Gilles Breuzard; Jean-Jacques Yaouanc; Jean-Claude Clément; Pierre Lehn; Chantal Pichon; Paul-Alain Jaffrès; Patrick Midoux
Synthesis and transfection activity of new cationic phosphoramidate lipids: high efficiency of an imidazolium derivative.
Chembiochem : a European journal of chemical biology 2008;9(9):1462-71.
2007: MOCKEY Michael; E Bourseau; V Chandrashekhar; A Chaudhuri; Sophie Lafosse; Eric Le Cam; Valerie QUESNIAUX; Bernhard RYFFEL; Chantal Pichon; Patrick Midoux
mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes.
Cancer gene therapy 2007;14(9):802-14.
2006: Eric Mennesson; Patrick Erbacher; Mateusz Kuzak; Claudine Kieda; Patrick Midoux; Chantal Pichon
DNA/cationic polymer complex attachment on a human vascular endothelial cell monolayer exposed to a steady laminar flow.
Journal of controlled release : official journal of the Controlled Release Society 2006;114(3):389-97.
2006: MOCKEY Michael; Christine Gonçalves; Franck P Dupuy; francois Lemoine; Chantal Pichon; Patrick Midoux
mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level.
Biochemical and biophysical research communications 2006;340(4):1062-8.
2005: Eric Mennesson; Patrick Erbacher; Véronique Piller; Claudine Kieda; Patrick Midoux; Chantal Pichon
Transfection efficiency and uptake process of polyplexes in human lung endothelial cells: a comparative study in non-polarized and polarized cells.
The journal of gene medicine 2005;7(6):729-38.
2004: Tristan Montier; Pascal Delépine; Chantal Pichon; Claude Férec; D J Porteous; Patrick Midoux
Non-viral vectors in cystic fibrosis gene therapy: progress and challenges.
Trends in biotechnology 2004;22(11):586-92.
2004: Ibrahim Elmadbouh; Patrick Rossignol; Olivier Meilhac; Roger Vranckx; Chantal Pichon; Bruno Pouzet; Patrick Midoux; Jean-Baptiste Michel
Optimization of in vitro vascular cell transfection with non-viral vectors for in vivo applications.
The journal of gene medicine 2004;6(10):1112-24.
2004: Christine Gonçalves; Eric Mennesson; Renate Fuchs; Jean-Pierre Gorvel; Patrick Midoux; Chantal Pichon
Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(2):373-85.
2004: Rajkumar Sunil Singh; Christine Gonçalves; Pierre Sandrin; Chantal Pichon; Patrick Midoux; Arabinda Chaudhuri
On the gene delivery efficacies of pH-sensitive cationic lipids via endosomal protonation: a chemical biology investigation.
Chemistry & biology 2004;11(5):713-23.
2003: Valluripalli Vinod Kumar; Chantal Pichon; M Refregiers; B Guerin; Patrick Midoux; Arabinda Chaudhuri
Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH.
Gene therapy 2003;10(15):1206-15.
2002: Patrick Midoux; Eric LeCam; Dominique Coulaud; Etienne Delain; Chantal Pichon
Histidine containing peptides and polypeptides as nucleic acid vectors.
Somatic cell and molecular genetics 2002;27(1-6):27-47.
2002: Chantal Pichon; Brigitte Guérin; Matthieu Réfrégiers; Christine Gonçalves; Paul Vigny; Patrick Midoux
Zinc improves gene transfer mediated by DNA/cationic polymer complexes.
The journal of gene medicine 2002;4(5):548-59.
2002: Christine Gonçalves; Chantal Pichon; Brigitte Guérin; Patrick Midoux
Intracellular processing and stability of DNA complexed with histidylated polylysine conjugates.
The journal of gene medicine 2002;4(3):271-81.
2002: Chantal Pichon; Eric LeCam; Brigitte Guérin; Dominique Coulaud; Etienne Delain; Patrick Midoux
Poly[Lys-(AEDTP)]: a cationic polymer that allows dissociation of pDNA/cationic polymer complexes in a reductive medium and enhances polyfection.
Bioconjugate chemistry 2002;13(1):76-82.
2001: Chantal Pichon; Christine Gonçalves; Patrick Midoux
Histidine-rich peptides and polymers for nucleic acids delivery.
Advanced drug delivery reviews 2001;53(1):75-94.
2000: Isabelle Fajac; J C Allo; Evelyne Souil; Marc Merten; Chantal Pichon; Catherine Figarella; Michel Monsigny; Pascale Briand; Patrick Midoux
Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells.
The journal of gene medicine 2000;2(5):368-78.
2000: Chantal Pichon; M B Roufaï; Michel Monsigny; Patrick Midoux
Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides.
Nucleic acids research 2000;28(2):504-12.
1999: Chantal Pichon; Michel Monsigny; Annie-Claude Roche
Intracellular localization of oligonucleotides: influence of fixative protocols.
Antisense & nucleic acid drug development 1999;9(1):89-93.
1998: Michel Monsigny; Christophe Quétard; S Bourgerie; Didier Delay; Chantal Pichon; Patrick Midoux; Roger Mayer; Annie-Claude Roche
Glycotargeting: the preparation of glyco-amino acids and derivatives from unprotected reducing sugars.
Biochimie 1998;80(2):99-108.
1997: Chantal Pichon; I Freulon; Patrick Midoux; Roger Mayer; Michel Monsigny; Annie-Claude Roche
Cytosolic and nuclear delivery of oligonucleotides mediated by an amphiphilic anionic peptide.
Antisense & nucleic acid drug development 1997;7(4):335-43.
1997: Chantal Pichon; K Arar; A J Stewart; Madeleine Duc Dodon; Louis Gazzolo; P J Courtoy; Roger Mayer; Michel Monsigny; Annie-Claude Roche
Intracellular routing and inhibitory activity of oligonucleopeptides containing a KDEL motif.
Molecular pharmacology 1997;51(3):431-8.
1996: A J Stewart; Chantal Pichon; L Meunier; Patrick Midoux; Michel Monsigny; Annie-Claude Roche
Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine.
Molecular pharmacology 1996;50(6):1487-94.