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Kenneth Pienta

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Kenneth J Pienta; Thomas A Puchalski; Dirk Schrijvers; Shobha Seetharam; Mikhail Shkolnik; Chris Takimoto; Boris Alekseev; Simon J Crabb; Fitzroy Dawkins; Yusri Elsayed; Susan Li; Jean-Pascal Machiels; Johann S de Bono
Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer.
Yusuke Shiozawa; Todd M Morgan; Biao Nie; Kenneth J Pienta; Russell S Taichman
Cancer stem cells and their role in metastasis.
Dan R Robinson; Sameek Roychowdhury; Scott M Schuetze; Javed Siddiqui; Samuel Singer; Fengyun Su; Yun-Shao Sung; Moshe Talpaz; Rui Wang; Yi-Mi Wu; Lei Zhang; Cristina R Antonescu; Xuhong Cao; Chun-Liang Chen; Matthew K Iyer; Shanker Kalyana-Sundaram; Lakshmi P Kunju; Robert J Lonigro; Juan Miguel Mosquera; Kenneth J Pienta; Arul M Chinnaiyan
Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing.

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All Publications

2013: Kenneth J Pienta; Thomas A Puchalski; Dirk Schrijvers; Shobha Seetharam; Mikhail Shkolnik; Chris Takimoto; Boris Alekseev; Simon J Crabb; Fitzroy Dawkins; Yusri Elsayed; Susan Li; Jean-Pascal Machiels; Johann S de Bono
Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer.
Investigational new drugs 2013;31(3):760-8.
2013: Yusuke Shiozawa; Todd M Morgan; Biao Nie; Kenneth J Pienta; Russell S Taichman
Cancer stem cells and their role in metastasis.
Pharmacology & therapeutics 2013;138(2):285-93.
2013: Dan R Robinson; Sameek Roychowdhury; Scott M Schuetze; Javed Siddiqui; Samuel Singer; Fengyun Su; Yun-Shao Sung; Moshe Talpaz; Rui Wang; Yi-Mi Wu; Lei Zhang; Cristina R Antonescu; Xuhong Cao; Chun-Liang Chen; Matthew K Iyer; Shanker Kalyana-Sundaram; Lakshmi P Kunju; Robert J Lonigro; Juan Miguel Mosquera; Kenneth J Pienta; Arul M Chinnaiyan
Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing.
Nature genetics 2013;45(2):180-5.
2013: Philip J Saylor; Matthew R Smith; Bertrand Tombal; Fred Saad; Andrew J Armstrong; Karim Fizazi; Stephen Freedland; Kenneth J Pienta
New and emerging therapies for bone metastases in genitourinary cancers.
European urology 2013;63(2):309-20.
2013: Steven Barthel; Monica M Burdick; Barbara A Foster; Bryan M Gillard; Danielle L Hays; Michael T Moser; Leonardo Nimrichter; Matthew Opperman; Klaus Pantel; Kenneth J Pienta; Kempland C Walley; Erika M Yazawa; Charles J Dimitroff
Definition of molecular determinants of prostate cancer cell bone extravasation.
Cancer research 2013;73(2):942-52.
2013: Younghun Jung; Evan T Keller; Jin Koo Kim; Paul H Krebsbach; Eunsohl Lee; Samantha McGee; Anjali Mishra; Kenneth J Pienta; Yusuke Shiozawa; Hongli Sun; Janice E Berry; Jinlu Dai; Taocong Jin; Jeena Joseph; Jingcheng Wang; Jianhua Wang; Honglai Zhang; Russell S Taichman
Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis.
Nature communications 2013;4():1795.
2013: Russell S Taichman; Jingcheng Wang; Savannah Weidner; Kenji Yumoto; Rachel Bedenis; Janice E Berry; Lalit R Patel; Taibriana Schumann; Yusuke Shiozawa; Kenneth J Pienta
GAS6 Receptor Status Is Associated with Dormancy and Bone Metastatic Tumor Formation.
PloS one 2013;8(4):e61873.
2013: Michelle L Jones; Kenneth J Pienta; Javed Siddiqui; Robert H Getzenberg
Circulating fibroblast-like cells in men with metastatic prostate cancer.
The Prostate 2013;73(2):176-81.
2012: Rui Wang; Heng Zheng; Irfan A Asangani; Bushra Ateeq; Daniel F Camacho; Qi Cao; Balabhadrapatruni V S K Chakravarthi; Arul M Chinnaiyan; Saravana M Dhanasekaran; Xiaojun Jing; Lakshmi P Kunju; Robert J Lonigro; Ram-Shankar Mani; Natalie McGregor; Rohit Mehra; Radhika Menawat; Mukesh K Nyati; Arie P Otte; Nallasivam Palanisamy; Kenneth J Pienta; Mark A Rubin; Taibriana E W Schumann; Javed Siddiqui; Scott A Tomlins; Sooryanarayana Lnu
Role of transcriptional corepressor CtBP1 in prostate cancer progression.
Neoplasia (New York, N.Y.) 2012;14(10):905-14.
2012: Bushra Ateeq; Qi Cao; Robert J Lonigro; Kenneth J Pienta; Scott A Tomlins; Adaikkalam Vellaichamy; Rui Wang; Sooryanarayana Lnu
Role of dutasteride in pre-clinical ETS fusion-positive prostate cancer models.
The Prostate 2012;72(14):1542-9.
2012: Zebin Hu; Chung Lee; Kenneth J Pienta; Arthur Berg; Charles B Brendler; Yun Ju Chen; Hongyan Du; Helen Gerseny; Theresa Guise; Janhavi Gupta; Paula H Stern; Stuart Stock; Xianghui Xiao; Zhenwei Zhang; Zhiling Zhang; Prem Seth
Systemic delivery of oncolytic adenoviruses targeting transforming growth factor-β inhibits established bone metastasis in a prostate cancer mouse model.
Human gene therapy 2012;23(8):871-82.
2012: Catherine S Grasso; Xiaojun Jing; Amjad P Khan; Lakshmi P Kunju; Robert J Lonigro; Rohit Mehra; Nallasivam Palanisamy; Kenneth J Pienta; John R Prensner; Michael J Quist; Benjamin J Raphael; Daniel R Rhodes; Dan R Robinson; Gregory A Ryslik; Lee Sam; Javed Siddiqui; Matt Anstett; Irfan A Asangani; Bushra Ateeq; J Chad Brenner; Xuhong Cao; Arul M Chinnaiyan; Sang Y Chun; Saravana M Dhanasekaran; Fabio Vandin; Yi-Mi Wu; Scott A Tomlins
The mutational landscape of lethal castration-resistant prostate cancer.
Nature 2012;487(7406):239-43.
2012: Anjali Mishra; Kenneth J Pienta; Yusuke Shiozawa; Janice E Berry; Aaron Havens; Jeena Joseph; Younghun Jung; Jinkoo Kim; Samantha McGee; Jingcheng Wang; Russell Taichman
Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.
Molecular cancer research : MCR 2012;10(6):703-12.
2012: Serk In Park; Kenneth J Pienta; David Sadler; Linda A Snyder; Fabiana N Soki; Sudha Sud; Sandra Tisdelle; Thomas J Wronski; Janice E Berry; Stephanie D Daignault; Matthew R Eber; Amy J Koh; Xin Li; Jinhui Liao; Megan E Michalski; Jeffrey A Nemeth; Laurie K McCauley
Cyclophosphamide creates a receptive microenvironment for prostate cancer skeletal metastasis.
Cancer research 2012;72(10):2522-32.
2012: Daniel F Camacho; Kenneth J Pienta
Disrupting the networks of cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(10):2801-8.
2012: Younghun Jung; Evan T Keller; Jin Koo Kim; Laurie K McCauley; Natalie McGregor; Serk In Park; Lalit Patel; Kenneth J Pienta; Yusuke Shiozawa; Janice E Berry; Peter Carmeliet; Jinlu Dai; Stephanie Daignault; Aaron Havens; Jeena Joseph; Jingcheng Wang; Russell Taichman
Prevalence of prostate cancer metastases after intravenous inoculation provides clues into the molecular basis of dormancy in the bone marrow microenvironment.
Neoplasia (New York, N.Y.) 2012;14(5):429-39.
2012: Elisabeth A Pedersen; Kenneth J Pienta; Yusuke Shiozawa; Russell Taichman
The prostate cancer bone marrow niche: more than just 'fertile soil'.
Asian journal of andrology 2012;14(3):423-7.
2012: Yee Seng Ng; Hernan Roca; Sudha Sud; David Fuller; Kenneth J Pienta
Chemical transfection of dye-conjugated microRNA precursors for microRNA functional analysis of M2 macrophages.
Journal of cellular biochemistry 2012;113(5):1714-23.
2012: Hernan Roca; Zachary S Varsos; Chi Ying; Ajjai S Alva; Matthew J Craig; Paul Czarnieski; Stephanie Daignault; David Fuller; Patrick N Healy; James Hernandez; Kenneth J Pienta
IL-4 induces proliferation in prostate cancer PC3 cells under nutrient-depletion stress through the activation of the JNK-pathway and survivin up-regulation.
Journal of cellular biochemistry 2012;113(5):1569-80.
2012: Amy Y Hsiao; Lalit R Patel; Kenneth J Pienta; Xianggui Qu; Yi-Chung Tung; Shuichi Takayama
384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids.
Biotechnology and bioengineering 2012;109(5):1293-304.
2012: Kenneth J Pienta; Marie C Gelato; Michael Lichtenstein
Forging the Association for Clinical and Translational Science (ACTS).
Clinical and translational science 2012;5(2):117-8.
2012: Amy Y Hsiao; Chuan-Hsien Kuo; Bobak Mosadegh; Kenneth J Pienta; Rachel Bedenis; Yi-Chung Tung; Shuichi Takayama
Micro-ring structures stabilize microdroplets to enable long term spheroid culture in 384 hanging drop array plates.
Biomedical microdevices 2012;14(2):313-23.
2012: Ajjai Alva; Michael A Carducci; Alice Chen; Kathleen Cooney; Stephanie Daignault; Robert Dipaola; Kenneth J Pienta; Susan Slovin; David C Smith; David Agus; Maha Hussain
Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium.
Investigational new drugs 2012;30(2):749-57.
2012: Jeena Joseph; Younghun Jung; Evan T Keller; Jin Koo Kim; Anjali Mishra; Elisabeth Pedersen; Kenneth J Pienta; Yusuke Shiozawa; Jingcheng Wang; Janet Linn Zalucha; Russell Taichman
Disseminated prostate cancer cells can instruct hematopoietic stem and progenitor cells to regulate bone phenotype.
Molecular cancer research : MCR 2012;10(3):282-92.
2012: Terence W Friedlander; Michael M Ittmann; Yasuko Kobayashi; Vy T Ngo; Kenneth J Pienta; Ritu Roy; Mark A Rubin; Charles J Ryan; Scott A Tomlins; Aruna Azameera; Arul M Chinnaiyan; Pamela L Paris
Common structural and epigenetic changes in the genome of castration-resistant prostate cancer.
Cancer research 2012;72(3):616-25.
2012: Chunyan Yu; Laurie K McCauley; Kenneth J Pienta; Yusuke Shiozawa; Russell S Taichman; Evan T Keller
Prostate cancer and parasitism of the bone hematopoietic stem cell niche.
Critical reviews in eukaryotic gene expression 2012;22(2):131-48.
2012: Olga V Glinskii; Gennadi V Glinsky; Douglas C Anthony; thomas mawhinney; Valeri V Mossine; Kenneth J Pienta; Sudha Sud; Vladislav V Glinsky
Inhibition of prostate cancer bone metastasis by synthetic TF antigen mimic/galectin-3 inhibitor lactulose-L-leucine.
Neoplasia (New York, N.Y.) 2012;14(1):65-73.
2011: Anjali Mishra; Yusuke Shiozawa; Kenneth J Pienta; Russell S Taichman
Homing of cancer cells to the bone.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2011;4(3):221-35.
2011: Deborah A Bradley; Alice Chen; Stephanie Daignault; Robert S Dipaola; Mitchell E Gross; Charles J Ryan; Eric Small; David C Smith; Mark N Stein; Gerald Doyle; Paul Mathew; Kathleen Cooney; Mahmoud M Al-Hawary; Kenneth J Pienta; Evan T Keller; June Escara-Wilke; Maha Hussain
Cilengitide (EMD 121974, NSC 707544) in asymptomatic metastatic castration resistant prostate cancer patients: a randomized phase II trial by the prostate cancer clinical trials consortium.
Investigational new drugs 2011;29(6):1432-40.
2011: Sameek Roychowdhury; Lee Sam; Javed Siddiqui; David C Smith; Moshe Talpaz; Patricia Troncoso; Yi-Mi Wu; John C Araujo; O Alejandro Balbin; Terrence barrette; Xuhong Cao; Jessica Everett; Stephen B Gruber; Jeffrey W Innis; Matthew K Iyer; Shanker Kalyana-Sundaram; Scott Y H Kim; Lakshmi P Kunju; Christopher D Lao; Christopher J Logothetis; Robert J Lonigro; Nora Navone; Kenneth J Pienta; Michael J Quist; J Scott Roberts; Dan R Robinson; Arul M Chinnaiyan
Personalized oncology through integrative high-throughput sequencing: a pilot study.
Science translational medicine 2011;3(111):111ra121.
2011: Himisha Beltran; Sung Suk Chae; Arul M Chinnaiyan; Colin C Collins; Alexandre de la Taille; Francesca Demichelis; Rajiv Dhir; Mark B Gerstein; Martin E Gleave; Theresa Y MacDonald; David M Nanus; Joel B Nelson; Kyung Park; Sven Perner; Kenneth J Pienta; David S Rickman; Andrea Sboner; Karen L Sheikh; Scott T Tagawa; Stéphane Terry; Yuwei Wang; Yuzhuo Wang; Yves Allory; Mark A Rubin
Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets.
Cancer discovery 2011;1(6):487-95.
2011: Robert J Lonigro; Kenneth J Pienta; Michael J Quist; Dan R Robinson; Scott A Tomlins; Yi-Mi Wu; Xuhong Cao; Catherine S Grasso; Xiaojun Jing; Arul M Chinnaiyan
Detection of somatic copy number alterations in cancer using targeted exome capture sequencing.
Neoplasia (New York, N.Y.) 2011;13(11):1019-25.
2011: Lalit R Patel; Kenneth J Pienta; Yusuke Shiozawa; Daniel F Camacho; Russell S Taichman
Mechanisms of cancer cell metastasis to the bone: a multistep process.
Future oncology (London, England) 2011;7(11):1285-97.
2011: Molly Dwyer-White; Mary Hill; Aalap Doshi; Kenneth J Pienta
Centralized research recruitment-evolving a local clinical research recruitment web application to better meet user needs.
Clinical and translational science 2011;4(5):363-8.
2011: Harry P Selker; Kenneth J Pienta
The importance of proposed changes in the "Common Rule" for -clinical and translational researchers.
Clinical and translational science 2011;4(5):312-3.
2011: Yusuke Shiozawa; Kenneth J Pienta; Russell Taichman
Hematopoietic stem cell niche is a potential therapeutic target for bone metastatic tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(17):5553-8.
2011: Kenneth J Pienta; Alison L Spork; Joan Scheske
The Clinical and Translational Science Awards (CTSAs) are transforming the way academic medical institutions approach translational research: the University of Michigan Experience.
Clinical and translational science 2011;4(4):233-5.
2011: Rohit Mehra; Neena E Philips; Xuhong Cao; Arul M Chinnaiyan; Bo Han; Xiaojun Jing; Chandan Kumar; Robert J Lonigro; Rajal B Shah; Sunita Shankar; Javed Siddiqui; David C Smith; Kenneth J Pienta
Characterization of bone metastases from rapid autopsies of prostate cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(12):3924-32.
2011: Xin Li; Jinhui Liao; Serk In Park; Amy J Koh; William D Sadler; Kenneth J Pienta; Thomas J Rosol; Laurie K McCauley
Drugs which inhibit osteoclast function suppress tumor growth through calcium reduction in bone.
Bone 2011;48(6):1354-61.
2011: J Chad Brenner; Bushra Ateeq; Yong Li; Anastasia K Yocum; Qi Cao; Irfan A Asangani; Sonam Patel; Xiaoju Wang; Hallie Liang; Jindan YU; Nallasivam Palanisamy; Javed Siddiqui; Wei Yan; Xuhong Cao; Rohit Mehra; Aaron Sabolch; venkatesha basrur; Robert J Lonigro; Jun Yang; Scott A Tomlins; Christopher A. Maher; Kojo Seys John Elenitoba-Johnson; Maha Hussain; Nora M Navone; Kenneth J Pienta; Sooryanarayana Lnu; Felix Y Feng; Arul M Chinnaiyan
Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.
Cancer cell 2011;19(5):664-78.
2011: Yusuke Shiozawa; Elisabeth A Pedersen; Aaron M Havens; Younghun Jung; Anjali Mishra; Jeena Joseph; Jin Koo Kim; Lalit R Patel; Chi Ying; Anne M Ziegler; Michael J Pienta; Junhui Song; Jingcheng Wang; Robert D Loberg; Paul H Krebsbach; Kenneth J Pienta; Russell Taichman
Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow.
The Journal of clinical investigation 2011;121(4):1298-312.
2011: Tong Sun; Lee Gwo-Shu Mary; William K Oh; Matthew L Freedman; Mark Pomerantz; Kenneth J Pienta; Philip W Kantoff
Inherited variants in the chemokine CCL2 gene and prostate cancer aggressiveness in a Caucasian cohort.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(6):1546-52.
2011: Bushra Ateeq; Scott A Tomlins; Bharathi Laxman; Irfan A Asangani; Qi Cao; Xuhong Cao; Yong Li; Xiaoju Wang; Felix Y Feng; Kenneth J Pienta; Sooryanarayana Lnu; Arul M Chinnaiyan
Therapeutic targeting of SPINK1-positive prostate cancer.
Science translational medicine 2011;3(72):72ra17.
2011: Remy Elbez; Lalit Patel; Brandon H McNaughton; Kenneth J Pienta; Raoul Kopelman
Nanoparticle induced cell magneto-rotation: monitoring morphology, stress and drug sensitivity of a suspended single cancer cell.
PloS one 2011;6(12):e28475.
2011: Kun-Wan Chen; Kenneth J Pienta
Modeling invasion of metastasizing cancer cells to bone marrow utilizing ecological principles.
Theoretical biology & medical modelling 2011;8():36.
2011: Jian Zhang; Sudha Sud; Kosuke Mizutani; Margaret R Gyetko; Kenneth J Pienta
Activation of urokinase plasminogen activator and its receptor axis is essential for macrophage infiltration in a prostate cancer mouse model.
Neoplasia (New York, N.Y.) 2011;13(1):23-30.
2011: Christiane M Robbins; Waibov A Tembe; Angela Baker; Shripad Sinari; Tracy Y Moses; Stephen Beckstrom-Sternberg; James Beckstrom-Sternberg; Michael Barrett; James Long; Arul M Chinnaiyan; James Lowey; Edward Suh; John Pearson; David Craig; David B Agus; Kenneth J Pienta; John D Carpten
Copy number and targeted mutational analysis reveals novel somatic events in metastatic prostate tumors.
Genome research 2011;21(1):47-55.
2011: Xin Li; Amy J Koh; Zhengyan Wang; Fabiana N Soki; Serk In Park; Kenneth J Pienta; Laurie K McCauley
Inhibitory effects of megakaryocytic cells in prostate cancer skeletal metastasis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(1):125-34.
2010: Kenneth J Pienta
Successfully accelerating translational research at an academic medical center: the University of Michigan-Coulter translational research partnership program.
Clinical and translational science 2010;3(6):316-8.
2010: Xueqing Sun; Guangcun Cheng; Mingang Hao; Jianghua Zheng; Xiaoming Zhou; Jian Zhang; Russell S Taichman; Kenneth J Pienta; Jianhua Wang
CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression.
Cancer metastasis reviews 2010;29(4):709-22.
2010: Natalie McGregor; Lalit Patel; Matthew Craig; Savannah Weidner; Shaomeng Wang; Kenneth J Pienta
AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model.
Journal of cellular biochemistry 2010;110(5):1187-94.
2010: Jian Zhang; Yi Lu; Kenneth J Pienta
Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth.
Journal of the National Cancer Institute 2010;102(8):522-8.
2010: Yusuke Shiozawa; Elisabeth A Pedersen; Lalit R Patel; Anne M Ziegler; Aaron Havens; Younghun Jung; Jingcheng Wang; Stephanie Zalucha; Robert D Loberg; Kenneth J Pienta; Russell Taichman
GAS6/AXL axis regulates prostate cancer invasion, proliferation, and survival in the bone marrow niche.
Neoplasia (New York, N.Y.) 2010;12(2):116-27.
2010: Jian Zhang; Lalit Patel; Kenneth J Pienta
CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis.
Cytokine & growth factor reviews 2010;21(1):41-8.
2010: Jianhua Wang; Gigi Ying; Jingchen Wang; Younghun Jung; Jian Lu; Jiang Zhu; Kenneth J Pienta; Russell S Taichman
Characterization of phosphoglycerate kinase-1 expression of stromal cells derived from tumor microenvironment in prostate cancer progression.
Cancer research 2010;70(2):471-80.
2010: Jian Zhang; Lalit Patel; Kenneth J Pienta
Targeting chemokine (C-C motif) ligand 2 (CCL2) as an example of translation of cancer molecular biology to the clinic.
Progress in molecular biology and translational science 2010;95():31-53.
2010: Yusuke Shiozawa; Younghun Jung; Anne M Ziegler; Elisabeth A Pedersen; Jianhua Wang; Zhuo Wang; Junhui Song; Jingcheng Wang; Clara H Lee; Sudha Sud; Kenneth J Pienta; Paul H Krebsbach; Russell S Taichman
Erythropoietin couples hematopoiesis with bone formation.
PloS one 2010;5(5):e10853.
2010: Carolyn M Sampselle; Kenneth J Pienta; Dorene S Markel
The CTSA mandate: are we there yet?
Research and theory for nursing practice 2010;24(1):64-73.
2009: Hernan Roca; Zachary S Varsos; Sudha Sud; Matthew J Craig; Chi Ying; Kenneth J Pienta
CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization.
The Journal of biological chemistry 2009;284(49):34342-54.
2009: Hernan Roca; Zachary S Varsos; Kenneth J Pienta
CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cells.
Neoplasia (New York, N.Y.) 2009;11(12):1309-17.
2009: Steven Barthel; Georg K Wiese; Jaehyung Cho; Matthew J Opperman; Danielle L Hays; Javed Siddiqui; Kenneth J Pienta; Bruce Furie; Charles J Dimitroff
Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19491-6.
2009: Kosuke Mizutani; Sudha Sud; Natalie A McGregor; Gari Martinovski; Brandon T Rice; Matthew J Craig; Zachary S Varsos; Hernan Roca; Kenneth J Pienta
The chemokine CCL2 increases prostate tumor growth and bone metastasis through macrophage and osteoclast recruitment.
Neoplasia (New York, N.Y.) 2009;11(11):1235-42.
2009: Kosuke Mizutani; Hernan Roca; Zachary Varsos; Kenneth J Pienta
Possible mechanism of CCL2-induced Akt activation in prostate cancer cells.
Anticancer research 2009;29(8):3109-13.
2009: Amy Y Hsiao; Yu-Suke Torisawa; Yi-Chung Tung; Sudha Sud; Russell S Taichman; Kenneth J Pienta; Shuichi Takayama
Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids.
Biomaterials 2009;30(16):3020-7.
2009: Mara P Steinkamp; Orla A O'Mahony; Michele Brogley; Haniya Rehman; Elizabeth W Lapensee; Saravana M Dhanasekaran; Matthias D Hofer; Rainer Kuefer; Arul M Chinnaiyan; Mark A Rubin; Kenneth J Pienta; Diane M Robins
Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy.
Cancer research 2009;69(10):4434-42.
2009: Kenneth J Pienta
Critical appraisal of prostate-specific antigen in prostate cancer screening: 20 years later.
Urology 2009;73(5 Suppl):S11-20.
2009: Stefan Rozel; Craig J Galban; Klaas Nicolay; Kuei C Lee; Sudha Sud; Chris Neeley; Linda A Snyder; Thomas L Chenevert; Alnawaz Rehemtulla; Brian D Ross; Kenneth J Pienta
Synergy between anti-CCL2 and docetaxel as determined by DW-MRI in a metastatic bone cancer model.
Journal of cellular biochemistry 2009;107(1):58-64.
2009: Yi Wang; Pratima Nangia-Makker; Larry Tait; Vitaly Balan; Victor Hogan; Kenneth J Pienta; Avraham Raz
Regulation of prostate cancer progression by galectin-3.
The American journal of pathology 2009;174(4):1515-23.
2009: Howard I Scher; Xiaoyu Jia; Johann S de Bono; Martin Fleisher; Kenneth J Pienta; Derek Raghavan; Glenn Heller
Circulating tumour cells as prognostic markers in progressive, castration-resistant prostate cancer: a reanalysis of IMMC38 trial data.
The lancet oncology 2009;10(3):233-9.
2009: Kosuke Mizutani; Sudha Sud; Kenneth J Pienta
Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts.
Journal of cellular biochemistry 2009;106(4):563-9.
2009: Seth A Rosenthal; Kyoungwha Bae; Kenneth J Pienta; Mark L Sobczak; Sucha O Asbell; Raghu Rajan; Kevin J Kerlin; Jeff M Michalski; Howard M Sandler
Phase III multi-institutional trial of adjuvant chemotherapy with paclitaxel, estramustine, and oral etoposide combined with long-term androgen suppression therapy and radiotherapy versus long-term androgen suppression plus radiotherapy alone for high-risk prostate cancer: preliminary toxicity analysis of RTOG 99-02.
International journal of radiation oncology, biology, physics 2009;73(3):672-8.
2009: Xin Li; Robert D Loberg; Jinhui Liao; Chi Ying; Linda A Snyder; Kenneth J Pienta; Laurie K McCauley
A destructive cascade mediated by CCL2 facilitates prostate cancer growth in bone.
Cancer research 2009;69(4):1685-92.
2009: Edwin M Posadas; Hikmat Al-Ahmadie; Victoria L Robinson; Ramasamy Jagadeeswaran; Kristen Otto; Kenneth E Kasza; Maria Tretiakov; Javed Siddiqui; Kenneth J Pienta; Walter M Stadler; Carrie W Rinker-Schaeffer; Ravi Salgia
FYN is overexpressed in human prostate cancer.
BJU international 2009;103(2):171-7.
2008: Yao Dai; Meilan Liu; Wenhua Tang; Jeffrey DeSano; Ezra Burstein; Mary Davis; Kenneth J Pienta; Theodore S Lawrence; Liang Xu
Molecularly targeted radiosensitization of human prostate cancer by modulating inhibitor of apoptosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(23):7701-10.
2008: Kenneth J Pienta; Natalie McGregor; Robert Axelrod; David E Axelrod
Ecological therapy for cancer: defining tumors using an ecosystem paradigm suggests new opportunities for novel cancer treatments.
Translational oncology 2008;1(4):158-64.
2008: Jinhui Liao; Xin Li; Amy J Koh; Janice E Berry; Nanda Thudi; Thomas J Rosol; Kenneth J Pienta; Laurie K McCauley
Tumor expressed PTHrP facilitates prostate cancer-induced osteoblastic lesions.
International journal of cancer. Journal international du cancer 2008;123(10):2267-78.
2008: Jill A Macoska; Shreelekha Adsule; Kwanchanit Tantivejkul; Shaomeng Wang; Kenneth J Pienta; Cheryl T Lee
-(-)Gossypol promotes the apoptosis of bladder cancer cells in vitro.
Pharmacological research : the official journal of the Italian Pharmacological Society 2008;58(5-6):323-31.
2008: Johann S de Bono; Howard I Scher; R Bruce Montgomery; Christopher Parker; M Craig Miller; Henk Tissing; Gerald V Doyle; Leon W W M Terstappen; Kenneth J Pienta; Derek Raghavan
Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(19):6302-9.
2008: Hernan Roca; Zachary S Varsos; Kosuke Mizutani; Kenneth J Pienta
CCL2, survivin and autophagy: new links with implications in human cancer.
Autophagy 2008;4(7):969-71.
2008: Yusuke Shiozawa; Aaron Havens; Younghun Jung; Anne M Ziegler; Elisabeth A Pedersen; Jianhua Wang; Jingcheng Wang; Ganwei Lu; David G Roodman; Robert D Loberg; Kenneth J Pienta; Russell Taichman
Annexin II/annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer.
Journal of cellular biochemistry 2008;105(2):370-80.
2008: Christopher L Hall; Stephanie D Daignault; Rajal B Shah; Kenneth J Pienta; Evan T Keller
Dickkopf-1 expression increases early in prostate cancer development and decreases during progression from primary tumor to metastasis.
The Prostate 2008;68(13):1396-404.
2008: Hernan Roca; Zachary Varsos; Kenneth J Pienta
CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation.
The Journal of biological chemistry 2008;283(36):25057-73.
2008: Kosuke Mizutani; Kenneth J Pienta
Re: RANKL inhibition is an effective adjuvant for docetaxel in a prostate cancer bone metastasis model.
European urology 2008;54(3):688.
2008: Carlton R Cooper; Bianca Graves; Freddie Pruitt; Hassan Chaib; Jill E Lynch; Andrew Koemeter Cox; Linda Sequeria; Kenneth L van Golen; Angelo Evans; Kirk Czymmek; Rebecca Linton; Carlton D Donald; Katia Sol-Church; James D Gendernalik; Babette Weksler; Mary C Farach-Carson; Jill A Macoska; Robert A Sikes; Kenneth J Pienta
Novel surface expression of reticulocalbin 1 on bone endothelial cells and human prostate cancer cells is regulated by TNF-alpha.
Journal of cellular biochemistry 2008;104(6):2298-309.
2008: Kenneth L van Golen; Chi Ying; Linda Sequeira; Cara W Dubyk; Tracy Reisenberger; Arul M Chinnaiyan; Kenneth J Pienta; Robert D Loberg
CCL2 induces prostate cancer transendothelial cell migration via activation of the small GTPase Rac.
Journal of cellular biochemistry 2008;104(5):1587-97.
2008: Yang Meng; Wenhua Tang; Yao Dai; Xiaoqing Wu; Meilan Liu; Qing Ji; Min Ji; Kenneth J Pienta; Theodore S Lawrence; Liang Xu
Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa.
Molecular cancer therapeutics 2008;7(7):2192-202.
2008: Rohit Mehra; Scott A Tomlins; Jianjun Yu; Xuhong Cao; Lei Wang; Anjana Menon; Mark A Rubin; Kenneth J Pienta; Rajal B Shah; Arul M Chinnaiyan
Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer.
Cancer research 2008;68(10):3584-90.
2008: Y Shiozawa; Aaron Havens; Kenneth J Pienta; Russell Taichman
The bone marrow niche: habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasites.
Leukemia 2008;22(5):941-50.
2008: Kenneth J Pienta; Cory Abate-Shen; David B Agus; Ricardo M Attar; Leland W K Chung; Norman M Greenberg; William C Hahn; John T Isaacs; Nora M Navone; Donna M Peehl; Jonathon W Simons; David B Solit; Howard R Soule; Terry A VanDyke; Michael J Weber; Lily Wu; Robert L Vessella
The current state of preclinical prostate cancer animal models.
The Prostate 2008;68(6):629-39.
2008: Aaron M Havens; Elisabeth A Pedersen; Yusuke Shiozawa; Chi Ying; Younghun Jung; Yanxi Sun; Chris K Neeley; Jincheng Wang; Rohit Mehra; Evan T Keller; Laurie K McCauley; Robert D Loberg; Kenneth J Pienta; Russell Taichman
An in vivo mouse model for human prostate cancer metastasis.
Neoplasia (New York, N.Y.) 2008;10(4):371-80.
2008: Sanjeev Shangary; Dongguang Qin; Donna McEachern; Meilan Liu; Rebecca S Miller; Su Qiu; Zaneta Nikolovska-Coleska; Ke Ding; Guoping Wang; Jianyong Chen; Denzil Bernard; Zhang Jian; Yipin Lu; Qingyang Gu; Rajal B Shah; Kenneth J Pienta; Xiaolan Ling; Sanmao Kang; Ming Guo; Yi Sun; Dajun Yang; Shaomeng Wang
Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3933-8.
2008: Jianhua Wang; Yusuke Shiozawa; Jincheng Wang; Yu Wang; Younghun Jung; Kenneth J Pienta; Rohit Mehra; Robert D Loberg; Russell Taichman
The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer.
The Journal of biological chemistry 2008;283(7):4283-94.
2008: Yan-Xi Sun; Elisabeth A Pedersen; Yusuke Shiozawa; Aaron Havens; Younghun Jung; Jingcheng Wang; Kenneth J Pienta; Russell Taichman
CD26/dipeptidyl peptidase IV regulates prostate cancer metastasis by degrading SDF-1/CXCL12.
Clinical & experimental metastasis 2008;25(7):765-76.
2008: Benjamin J Raphael; Stanislav Volik; Peng Yu; Chunxiao Wu; Guiqing Huang; Elena Linardopoulou; Barbara J Trask; Frederic Waldman; Joseph F Costello; Kenneth J Pienta; Gordon B Mills; Krystyna Bajsarowicz; Yasuko Kobayashi; Shivaranjani Sridharan; Pamela L Paris; Quanzhou Tao; Sarah J Aerni; Raymond P Brown; Ali Bashir; Joe Gray; Jan-Fang Cheng; Pieter de Jong; Mikhail Nefedov; Thomas Ried; Hesed Padilla-Nash; Colin C Collins
A sequence-based survey of the complex structural organization of tumor genomes.
Genome biology 2008;9(3):R59.
2007: Laurel L Northouse; Darlene Mood; Ann Schafenacker; James E Montie; Howard M Sandler; Jeffrey D Forman; Maha Hussain; Kenneth J Pienta; David C Smith; Trace S Kershaw
Randomized clinical trial of a family intervention for prostate cancer patients and their spouses.
Cancer 2007;110(12):2809-18.
2007: Robert D Loberg; Natalie McGregor; Chi Ying; Erin Sargent; Kenneth J Pienta
In vivo evaluation of AT-101 (R-(-)-gossypol acetic acid) in androgen-independent growth of VCaP prostate cancer cells in combination with surgical castration.
Neoplasia (New York, N.Y.) 2007;9(12):1030-7.
2007: Kuei Lee; Deborah A Bradley; Maha Hussain; Charles R Meyer; Thomas L Chenevert; Jon A Jacobson; Timothy D Johnson; Craig J Galban; Alnawaz Rehemtulla; Kenneth J Pienta; Brian D Ross
A feasibility study evaluating the functional diffusion map as a predictive imaging biomarker for detection of treatment response in a patient with metastatic prostate cancer to the bone.
Neoplasia (New York, N.Y.) 2007;9(12):1003-11.
2007: Jindan YU; Jianjun Yu; Daniel R Rhodes; Scott A Tomlins; Xuhong Cao; Guoan Chen; Rohit Mehra; Xiaoju Wang; Debashis Ghosh; Rajal B Shah; Sooryanarayana Lnu; Kenneth J Pienta; Arul M Chinnaiyan
A polycomb repression signature in metastatic prostate cancer predicts cancer outcome.
Cancer research 2007;67(22):10657-63.
2007: Evan T Keller; David R Rowley; Scott A Tomlins; Charles G Drake; Philip W Kantoff; Kenneth J Pienta; James E Montie; H Ballentine Carter; Andrew M Hruszkewicz; Jorge Gomez; Suresh Mohla; Robert H Getzenberg
Eleventh Prouts Neck Meeting on Prostate Cancer: emerging strategies in prostate cancer therapy.
Cancer research 2007;67(20):9613-5.
2007: Robert D Loberg; Chi Ying; Matthew Craig; LaShon L Day; Erin Sargent; Chris K Neeley; Kirk J Wojno; Linda A Snyder; Li Yan; Kenneth J Pienta
Targeting CCL2 with systemic delivery of neutralizing antibodies induces prostate cancer tumor regression in vivo.
Cancer research 2007;67(19):9417-24.
2007: Laurel L Northouse; Darlene Mood; James E Montie; Howard M Sandler; Jeffrey D Forman; Maha Hussain; Kenneth J Pienta; David C Smith; Martin G Sanda; Trace S Kershaw
Living with prostate cancer: patients' and spouses' psychosocial status and quality of life.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(27):4171-7.
2007: Jung H Kim; Saravana M Dhanasekaran; Rohit Mehra; Scott A Tomlins; Wenjuan Gu; Jianjun Yu; Chandan Kumar; Xuhong Cao; Atreya Dash; Lei Wang; Debashis Ghosh; Kerby Shedden; James E Montie; Mark A Rubin; Kenneth J Pienta; Rajal B Shah; Arul M Chinnaiyan
Integrative analysis of genomic aberrations associated with prostate cancer progression.
Cancer research 2007;67(17):8229-39.
2007: Russell Taichman; Robert D Loberg; Rohit Mehra; Kenneth J Pienta
The evolving biology and treatment of prostate cancer.
The Journal of clinical investigation 2007;117(9):2351-61.
2007: Qianben Wang; Wei Li; Xiaole (Shirley) Liu; Jason S Carroll; Olli A Jänne; Erika Krasnickas Keeton; Arul M Chinnaiyan; Kenneth J Pienta; Myles Brown
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth.
Molecular cell 2007;27(3):380-92.
2007: Scott A Tomlins; Bharathi Laxman; Saravana M Dhanasekaran; Beth E Helgeson; Xuhong Cao; David S Morris; Anjana Menon; Xiaojun Jing; Qi Cao; Bo Han; Jindan YU; Lei Wang; James E Montie; Mark A Rubin; Kenneth J Pienta; Diane Roulston; Rajal B Shah; Sooryanarayana Lnu; Rohit Mehra; Arul M Chinnaiyan
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer.
Nature 2007;448(7153):595-9.
2007: Kim D Johnson; Olga V Glinskii; Valeri V Mossine; James Turk; thomas mawhinney; Douglas C Anthony; Carolyn J Henry; V. H. Huxley; Gennadi V Glinsky; Kenneth J Pienta; Avraham Raz; Vladislav V Glinsky
Galectin-3 as a potential therapeutic target in tumors arising from malignant endothelia.
Neoplasia (New York, N.Y.) 2007;9(8):662-70.
2007: Robert D Loberg; Kwanchanit Tantivejkul; Matthew Craig; Chris K Neeley; Kenneth J Pienta
PAR1-mediated RhoA activation facilitates CCL2-induced chemotaxis in PC-3 cells.
Journal of cellular biochemistry 2007;101(5):1292-300.
2007: Robert D Loberg; Chi Ying; Matthew Craig; Li Yan; Linda A Snyder; Kenneth J Pienta
CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration.
Neoplasia (New York, N.Y.) 2007;9(7):556-62.
2007: Robert D Loberg; Deborah A Bradley; Scott A Tomlins; Arul M Chinnaiyan; Kenneth J Pienta
The lethal phenotype of cancer: the molecular basis of death due to malignancy.
CA: a cancer journal for clinicians 2007;57(4):225-41.
2007: Niklas J Mackler; Kenneth J Pienta; Rodney L Dunn; Kathleen Cooney; Bruce G Redman; Karin B Olson; Judith Fardig; David C Smith
Phase II evaluation of oral estramustine, oral etoposide, and intravenous paclitaxel in patients with hormone-sensitive prostate adenocarcinoma.
Clinical genitourinary cancer 2007;5(5):318-22.
2007: Rohit Mehra; Scott A Tomlins; Ronglai Shen; Owais Nadeem; Lei Wang; John T Wei; Kenneth J Pienta; Debashis Ghosh; Mark A Rubin; Arul M Chinnaiyan; Rajal B Shah
Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(5):538-44.
2007: Kuei Lee; Sudha Sud; Charles R Meyer; Bradford Moffat; Thomas L Chenevert; Alnawaz Rehemtulla; Kenneth J Pienta; Brian D Ross
An imaging biomarker of early treatment response in prostate cancer that has metastasized to the bone.
Cancer research 2007;67(8):3524-8.
2007: Jianhua Wang; Jincheng Wang; Jinlu Dai; Younghun Jung; Chuen-Long Wei; Yu Wang; Aaron Havens; Phillip J Hogg; Evan T Keller; Kenneth J Pienta; Jacques E Nor; Cun-Yu Wang; Russell Taichman
A glycolytic mechanism regulating an angiogenic switch in prostate cancer.
Cancer research 2007;67(1):149-59.
2007: Scott A Tomlins; Rohit Mehra; Daniel R Rhodes; Xuhong Cao; Lei Wang; Saravana M Dhanasekaran; Shanker Kalyana-Sundaram; John T Wei; Mark A Rubin; Kenneth J Pienta; Rajal B Shah; Arul M Chinnaiyan
Integrative molecular concept modeling of prostate cancer progression.
Nature genetics 2007;39(1):41-51.
2007: Yan-Xi Sun; Ming Fang; Jianhua Wang; Carlton R Cooper; Kenneth J Pienta; Russell Taichman
Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells.
The Prostate 2007;67(1):61-73.
2006: Robert Axelrod; David E Axelrod; Kenneth J Pienta
Evolution of cooperation among tumor cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(36):13474-9.
2006: Sven Perner; Francesca Demichelis; Rameen Beroukhim; Folke H Schmidt; Juan-Miguel Mosquera; Sunita R Setlur; Joëlle Tchinda; Scott A Tomlins; Matthias D Hofer; Kenneth J Pienta; Rainer Kuefer; Robert L Vessella; Xiao-Wei Sun; Matthew Meyerson; Charles Lee; William R Sellers; Arul M Chinnaiyan; Mark A Rubin
TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer.
Cancer research 2006;66(17):8337-41.
2006: Sabrina L Spencer; Ryan A Gerety; Kenneth J Pienta; Stephanie Forrest
Modeling somatic evolution in tumorigenesis.
PLoS computational biology 2006;2(8):e108.
2006: Robert D Loberg; LaShon L Day; Jason Harwood; Chi Ying; Lauren N St John; Ryan Giles; Chris K Neeley; Kenneth J Pienta
CCL2 is a potent regulator of prostate cancer cell migration and proliferation.
Neoplasia (New York, N.Y.) 2006;8(7):578-86.
2006: Niklas J Mackler; Rodney L Dunn; Beth A Hellerstedt; Kathleen Cooney; Judith Fardig; Karin Olson; Kenneth J Pienta; David C Smith
Dose escalation of oral vinorelbine in combination with estramustine in hormone-refractory adenocarcinoma of the prostate.
Cancer 2006;106(12):2617-23.
2006: James M Rae; Michael Johnson; Kevin E Cordero; Joshua O Scheys; Jose M Larios; Marco Gottardis; Kenneth J Pienta; Marc Lippman
GREB1 is a novel androgen-regulated gene required for prostate cancer growth.
The Prostate 2006;66(8):886-94.
2006: Manish S Bhandari; Kenneth J Pienta; Judith Fardig; Karin Olson; David C Smith
Phase II trial of oral uracil/tegafur plus leucovorin in patients with hormone-refractory prostate carcinoma.
Cancer 2006;106(8):1715-21.
2006: Kenneth J Pienta; Deborah A Bradley
Mechanisms underlying the development of androgen-independent prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1665-71.
2006: Kathleen W Beekman; A Dimitrios Colevas; Kathleen Cooney; Robert Dipaola; Rodney L Dunn; Mitchell Gross; Evan T Keller; Kenneth J Pienta; Charles J Ryan; David C Smith; Maha Hussain
Phase II evaluations of cilengitide in asymptomatic patients with androgen-independent prostate cancer: scientific rationale and study design.
Clinical genitourinary cancer 2006;4(4):299-302.
2006: Robert D Loberg; Lauren N St John; LaShon L Day; Chris K Neeley; Kenneth J Pienta
Development of the VCaP androgen-independent model of prostate cancer.
Urologic oncology 2006;24(2):161-8.
2006: N Lynn Henry; Rodney Dunn; Sofia Merjaver; Quintin Pan; Kenneth J Pienta; George Brewer; David C Smith
Phase II trial of copper depletion with tetrathiomolybdate as an antiangiogenesis strategy in patients with hormone-refractory prostate cancer.
Oncology 2006;71(3-4):168-75.
2006: Robert G Abbott; Stephanie Forrest; Kenneth J Pienta
Simulating the hallmarks of cancer.
Artificial life 2006;12(4):617-34.
2006: Aaron Havens; Younghun Jung; Yan-Xi Sun; Jingcheng Wang; Rajal B Shah; H J Bühring; Kenneth J Pienta; Russell Taichman
The role of sialomucin CD164 (MGC-24v or endolyn) in prostate cancer metastasis.
BMC cancer 2006;6():195.
2006: Karin B Olson; Kenneth J Pienta
Prostate cancer presenting as visual changes.
Anticancer research 2006;26(1B):755-8.
2006: Robert D Loberg; LaShon L Day; Rodney Dunn; Linda M Kalikin; Kenneth J Pienta
Inhibition of decay-accelerating factor (CD55) attenuates prostate cancer growth and survival in vivo.
Neoplasia (New York, N.Y.) 2006;8(1):69-78.
2005: Asmita R Patel; Howard M Sandler; Kenneth J Pienta
Radiation Therapy Oncology Group 0521: a phase III randomized trial of androgen suppression and radiation therapy versus androgen suppression and radiation therapy followed by chemotherapy with docetaxel/prednisone for localized, high-risk prostate cancer.
Clinical genitourinary cancer 2005;4(3):212-4.
2005: Robert D Loberg; Kirk J Wojno; LaShon L Day; Kenneth J Pienta
Analysis of membrane-bound complement regulatory proteins in prostate cancer.
Urology 2005;66(6):1321-6.
2005: Shahriar Koochekpour; Yu-Jun Zhuang; Rameen Beroukhim; Chia-Ling Hsieh; Matthias D Hofer; Haiyen E Zhau; Masao Hiraiwa; Daniel Y Pattan; Joy L Ware; Ronald B Luftig; Konrad Sandhoff; Charles L Sawyers; Kenneth J Pienta; Mark A Rubin; Robert L Vessella; William R Sellers; Oliver Sartor
Amplification and overexpression of prosaposin in prostate cancer.
Genes, chromosomes & cancer 2005;44(4):351-64.
2005: Robert D Loberg; Christopher J Logothetis; Evan T Keller; Kenneth J Pienta
Pathogenesis and treatment of prostate cancer bone metastases: targeting the lethal phenotype.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(32):8232-41.
2005: Sooryanarayana Lnu; Jianjun Yu; Bharathi Laxman; Daniel R Rhodes; Rohit Mehra; Scott A Tomlins; Rajal B Shah; Uma Chandran; Federico Monzon; Michael Becich; John T Wei; Kenneth J Pienta; Debashis Ghosh; Mark A Rubin; Arul M Chinnaiyan
Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression.
Cancer cell 2005;8(5):393-406.
2005: Scott A Tomlins; Daniel R Rhodes; Sven Perner; Saravana M Dhanasekaran; Rohit Mehra; Xiao-Wei Sun; Sooryanarayana Lnu; Xuhong Cao; Joëlle Tchinda; Rainer Kuefer; Charles Lee; James E Montie; Rajal B Shah; Kenneth J Pienta; Mark A Rubin; Arul M Chinnaiyan
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
Science (New York, N.Y.) 2005;310(5748):644-8.
2005: Kwanchanit Tantivejkul; Robert D Loberg; Samkeliso C Mawocha; LaShon L Day; Lauren St John; Brian A Pienta; Mark A Rubin; Kenneth J Pienta
PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism.
Journal of cellular biochemistry 2005;96(3):641-52.
2005: Robert D Loberg; Bishoy A Gayed; Karin B Olson; Kenneth J Pienta
A paradigm for the treatment of prostate cancer bone metastases based on an understanding of tumor cell-microenvironment interactions.
Journal of cellular biochemistry 2005;96(3):439-46.
2005: Xiaoju Wang; Jianjun Yu; Arun Sreekumar; Sooryanarayana Lnu; Ronglai Shen; Donald Giacherio; Rohit Mehra; James E Montie; Kenneth J Pienta; Martin G Sanda; Philip W Kantoff; Mark A Rubin; John T Wei; Debashis Ghosh; Arul M Chinnaiyan
Autoantibody signatures in prostate cancer.
The New England journal of medicine 2005;353(12):1224-35.
2005: Kenneth J Pienta; David C Smith
Advances in prostate cancer chemotherapy: a new era begins.
CA: a cancer journal for clinicians 2005;55(5):300-18; quiz 323-5.
2005: Karin B Olson; C Michael Hellie; Kenneth J Pienta
Osteonecrosis of jaw in patient with hormone-refractory prostate cancer treated with zoledronic acid.
Urology 2005;66(3):658.
2005: Asmita R Patel; Karin B Olson; Kenneth J Pienta
Proptosis and decreased vision secondary to prostate cancer orbital wall metastasis.
Anticancer research 2005;25(5):3521-2.
2005: Charles J Dimitroff; Leyla Descheny; Natalia Trujillo; Robert Kim; Vuong Nguyen; Wei Huang; Kenneth J Pienta; Jeffery L Kutok; Mark A Rubin
Identification of leukocyte E-selectin ligands, P-selectin glycoprotein ligand-1 and E-selectin ligand-1, on human metastatic prostate tumor cells.
Cancer research 2005;65(13):5750-60.
2005: Denis A Smirnov; Daniel R Zweitzig; Bradley W Foulk; M Craig Miller; Gerald V Doyle; Kenneth J Pienta; Neal J Meropol; Louis M Weiner; Steven J Cohen; Jose G Moreno; Mark C Connelly; Leon W M M Terstappen; S Mark O'Hara
Global gene expression profiling of circulating tumor cells.
Cancer research 2005;65(12):4993-7.
2005: Kenneth J Pienta; Robert D Loberg
The "emigration, migration, and immigration"of prostate cancer.
Clinical prostate cancer 2005;4(1):24-30.
2005: Robert D Loberg; Chris K Neeley; Lashon L Adam-Day; Yaron Fridman; Lauren N St John; Sheri Nixdorf; Paul Jackson; Linda M Kalikin; Kenneth J Pienta
Differential expression analysis of MIM (MTSS1) splice variants and a functional role of MIM in prostate cancer cell biology.
International journal of oncology 2005;26(6):1699-705.
2005: Olga V Glinskii; V. H. Huxley; Gennadi V Glinsky; Kenneth J Pienta; Avraham Raz; Vladislav V Glinsky
Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs.
Neoplasia (New York, N.Y.) 2005;7(5):522-7.
2005: Abraham Schneider; Linda M Kalikin; Ana C Mattos; Evan T Keller; Matthew J Allen; Kenneth J Pienta; Laurie K McCauley
Bone turnover mediates preferential localization of prostate cancer in the skeleton.
Endocrinology 2005;146(4):1727-36.
2005: Bert T Chen; Robert D Loberg; Chris K Neeley; S Mark O'Hara; Steve Gross; Gerald V Doyle; Rodney L Dunn; Linda M Kalikin; Kenneth J Pienta
Preliminary study of immunomagnetic quantification of circulating tumor cells in patients with advanced disease.
Urology 2005;65(3):616-21.
2005: Niklas J Mackler; Kenneth J Pienta
Drug insight: Use of docetaxel in prostate and urothelial cancers.
Nature clinical practice. Urology 2005;2(2):92-100; quiz 1 p following 112.
2005: Yan-Xi Sun; Abraham Schneider; Younghun Jung; Jianhua Wang; Jinlu Dai; Jingcheng Wang; Kevin Cook; Nadir I Osman; Amy J Koh-Paige; Hyunsuk Shim; Kenneth J Pienta; Evan T Keller; Laurie K McCauley; Russell Taichman
Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(2):318-29.
2005: Pradip Roy-Burman; Donald J Tindall; Diane M Robins; Norman M Greenberg; Mary J C Hendrix; Suresh Mohla; Robert H Getzenberg; John T Isaacs; Kenneth J Pienta
Androgens and prostate cancer: are the descriptors valid?
Cancer biology & therapy 2005;4(1):4-5.
2004: Rajal B Shah; Rohit Mehra; Arul M Chinnaiyan; Ronglai Shen; Debashis Ghosh; Ming Zhou; Gary R MacVicar; Sooryanarayana Lnu; Jason Harwood; Tarek A Bismar; Robert Kim; Mark A Rubin; Kenneth J Pienta
Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program.
Cancer research 2004;64(24):9209-16.
2004: Sheri Nixdorf; Marc-Oliver Grimm; Robert D Loberg; Alexandra Marreiros; Pamela J Russell; Kenneth J Pienta; Paul Jackson
Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines.
Cancer letters 2004;215(2):209-20.
2004: Christopher J Larson; Jose G Moreno; Kenneth J Pienta; Steve Gross; Madeline Repollet; S Mark O'Hara; Thomas Russell; Leon W M M Terstappen
Apoptosis of circulating tumor cells in prostate cancer patients.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2004;62(1):46-53.
2004: Matthias D Hofer; Alice Fecko; Ronglai Shen; Sunita R Setlur; Kenneth J Pienta; Scott A Tomlins; Arul M Chinnaiyan; Mark A Rubin
Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors.
Neoplasia (New York, N.Y.) 2004;6(5):503-12.
2004: Robert D Loberg; Yaron Fridman; Brian A Pienta; Evan T Keller; Laurie K McCauley; Russell Taichman; Kenneth J Pienta
Detection and isolation of circulating tumor cells in urologic cancers: a review.
Neoplasia (New York, N.Y.) 2004;6(4):302-9.
2004: Pamela L Paris; Armann Andaya; Jane Fridlyand; Ajay N Jain; Vivian Weinberg; David Kowbel; John H Brebner; Jeff Simko; J E Vivienne Watson; Stanislav Volik; Donna G Albertson; Daniel Pinkel; Janneke C Alers; Theo Van der Kwast; Kees J Vissers; Fritz H Schroder; Mark F Wildhagen; Phillip G Febbo; Arul M Chinnaiyan; Kenneth J Pienta; Peter R Carroll; Mark A Rubin; Colin Collins; Herman van Dekken
Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors.
Human molecular genetics 2004;13(13):1303-13.
2004: Robert A Sikes; Brian E Nicholson; Kenneth S Koeneman; N Magnus Edlund; Eric A Bissonette; Michael J Bradley; George N Thalmann; Marco G Cecchini; Kenneth J Pienta; Leland W K Chung
Cellular interactions in the tropism of prostate cancer to bone.
International journal of cancer. Journal international du cancer 2004;110(4):497-503.
2004: Mark A Rubin; Sooryanarayana Lnu; Rameen Beroukhim; Scott A Tomlins; Daniel R Rhodes; Pamela L Paris; Matthias D Hofer; Martina Storz-Schweizer; Rainer Kuefer; Jonathan A Fletcher; Bae-Li Hsi; Jennifier A Byrne; Kenneth J Pienta; Colin Collins; William R Sellers; Arul M Chinnaiyan
Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer.
Cancer research 2004;64(11):3814-22.
2004: Jian Zhang; Yi Lu; Jinlu Dai; Zhi Yao; Riko Kitazawa; Sohei Kitazawa; Xinping Zhao; Daniel E Hall; Kenneth J Pienta; Evan T Keller
In vivo real-time imaging of TGF-beta-induced transcriptional activation of the RANK ligand gene promoter in intraosseous prostate cancer.
The Prostate 2004;59(4):360-9.
2004: Gary R MacVicar; Kenneth J Pienta
Testicular cancer.
Current opinion in oncology 2004;16(3):253-6.
2004: Adam S Kibel; John Huagen; Chan Guo; William B Isaacs; Yan Yan; Kenneth J Pienta; Paul J Goodfellow
Expression mapping at 12p12-13 in advanced prostate carcinoma.
International journal of cancer. Journal international du cancer 2004;109(5):668-72.
2004: Kwanchanit Tantivejkul; Linda M Kalikin; Kenneth J Pienta
Dynamic process of prostate cancer metastasis to bone.
Journal of cellular biochemistry 2004;91(4):706-17.
2004: Howard I Scher; Mario A Eisenberger; Anthony V D'Amico; Susan Halabi; Eric J Small; Michael J Morris; Michael W Kattan; Mack Roach; Philip W Kantoff; Kenneth J Pienta; Michael A Carducci; David B Agus; Susan F Slovin; Glenn Heller; W Kevin Kelly; Paul H Lange; Daniel P Petrylak; William Berg; Celestia S Higano; George Wilding; Judd W Moul; Alan W Partin; Christopher Logothetis; Howard R Soule
Eligibility and outcomes reporting guidelines for clinical trials for patients in the state of a rising prostate-specific antigen: recommendations from the Prostate-Specific Antigen Working Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(3):537-56.
2004: Carlton R Cooper; Robert A Sikes; Brian E Nicholson; Yan-Xi Sun; Kenneth J Pienta; Russell Taichman
Cancer cells homing to bone: the significance of chemotaxis and cell adhesion.
Cancer treatment and research 2004;118():291-309.
2004: Olga V Glinskii; James Turk; Kenneth J Pienta; V. H. Huxley; Vladislav V Glinsky
Evidence of porcine and human endothelium activation by cancer-associated carbohydrates expressed on glycoproteins and tumour cells.
The Journal of physiology 2004;554(Pt 1):89-99.
2003: Robert D Loberg; Jeffery R Fielhauer; Brian A Pienta; Scott Dresden; Patty Christmas; Linda M Kalikin; Karin B Olson; Kenneth J Pienta
Prostate-specific antigen doubling time and survival in patients with advanced metastatic prostate cancer.
Urology 2003;62 Suppl 1():128-33.
2003: Kenneth J Pienta
Radiation Therapy Oncology Group P-0014: a phase 3 randomized study of patients with high-risk hormone-naive prostate cancer: androgen blockade with 4 cycles of immediate chemotherapy versus androgen blockade with delayed chemotherapy.
Urology 2003;62 Suppl 1():95-101.
2003: Rainer Kuefer; Matthias D Hofer; Juergen E Gschwend; Kenneth J Pienta; Martin G Sanda; Arul M Chinnaiyan; Mark A Rubin; Mark Day
The role of an 80 kDa fragment of E-cadherin in the metastatic progression of prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(17):6447-52.
2003: Linda M Kalikin; Abraham Schneider; Melissa A Thakur; Yaron Fridman; Laura B Griffin; Rodney L Dunn; Thomas J Rosol; Rajal B Shah; Alnawaz Rehemtulla; Laurie K McCauley; Kenneth J Pienta
In vivo visualization of metastatic prostate cancer and quantitation of disease progression in immunocompromised mice.
Cancer biology & therapy 2003;2(6):656-60.
2003: Beth A Hellerstedt; Kenneth J Pienta; Bruce G Redman; Peg Esper; Rodney Dunn; Judith Fardig; Karin Olson; David C Smith
Phase II trial of oral cyclophosphamide, prednisone, and diethylstilbestrol for androgen-independent prostate carcinoma.
Cancer 2003;98(8):1603-10.
2003: David C Smith; Christopher H Chay; Rodney L Dunn; Judith Fardig; Peg Esper; Karin Olson; Kenneth J Pienta
Phase II trial of paclitaxel, estramustine, etoposide, and carboplatin in the treatment of patients with hormone-refractory prostate carcinoma.
Cancer 2003;98(2):269-76.
2003: Beth A Hellerstedt; Kenneth J Pienta
The truth is out there: an overall perspective on androgen deprivation.
Urologic oncology 2003;21(4):272-81.
2003: Vladislav V Glinsky; Gennadi V Glinsky; Olga V Glinskii; V. H. Huxley; James Turk; Valeri V Mossine; Susan L Deutscher; Kenneth J Pienta; Thomas P Quinn
Intravascular metastatic cancer cell homotypic aggregation at the sites of primary attachment to the endothelium.
Cancer research 2003;63(13):3805-11.
2003: Yan-Xi Sun; Jingcheng Wang; Charles E Shelburne; Dennis E Lopatin; Arul M Chinnaiyan; Mark A Rubin; Kenneth J Pienta; Russell Taichman
Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo.
Journal of cellular biochemistry 2003;89(3):462-73.
2003: Beth A Hellerstedt; Kenneth J Pienta
Germ cell tumors: review of selected studies from 2002.
Current opinion in oncology 2003;15(3):234-8.
2003: Hyung-Lae Lee; Kenneth J Pienta; Wun-Jae Kim; Carlton R Cooper
The effect of bone-associated growth factors and cytokines on the growth of prostate cancer cells derived from soft tissue versus bone metastases in vitro.
International journal of oncology 2003;22(4):921-6.
2003: Carlton R Cooper; Christopher H Chay; James D Gendernalik; Hyung-Lae Lee; Jasmine K Bhatia; Russell Taichman; Laurie K McCauley; Evan T Keller; Kenneth J Pienta
Stromal factors involved in prostate carcinoma metastasis to bone.
Cancer 2003;97(3 Suppl):739-47.
2003: Howard M Sandler; Kenneth J Pienta
Rationale for the Radiation Therapy Oncology Group Study RTOG P-0014.
Reviews in urology 2003;5 Suppl 2():S28-34.
2003: Howard M Sandler; Kenneth J Pienta
Rationale for the Radiation Therapy Oncology Group Study RTOG P-0014.
Reviews in urology 2003;5 Suppl 3():S45-51.
2003: Olga V Glinskii; V. H. Huxley; James Turk; Susan L Deutscher; Thomas P Quinn; Kenneth J Pienta; Vladislav V Glinsky
Continuous real time ex vivo epifluorescent video microscopy for the study of metastatic cancer cell interactions with microvascular endothelium.
Clinical & experimental metastasis 2003;20(5):451-8.
2002: Christopher H Chay; Carlton R Cooper; James D Gendernalik; Saravana M Dhanasekaran; Arul M Chinnaiyan; Mark A Rubin; Alvin H Schmaier; Kenneth J Pienta
A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines.
Urology 2002;60(5):760-5.
2002: Sooryanarayana Lnu; Saravana M Dhanasekaran; Ming Zhou; Terrence barrette; Chandan Kumar; Martin G Sanda; Debashis Ghosh; Kenneth J Pienta; Richard G A B Sewalt; Arie P Otte; Mark A Rubin; Arul M Chinnaiyan
The polycomb group protein EZH2 is involved in progression of prostate cancer.
Nature 2002;419(6907):624-9.
2002: Kenneth L van Golen; LiWei Bao; George J Brewer; Kenneth J Pienta; Jeffrey M Kamradt; Donna L Livant; Sofia D Merajver
Suppression of tumor recurrence and metastasis by a combination of the PHSCN sequence and the antiangiogenic compound tetrathiomolybdate in prostate carcinoma.
Neoplasia (New York, N.Y.) 2002;4(5):373-9.
2002: Young-Goo Lee; Jill A Macoska; Susan Korenchuk; Kenneth J Pienta
MIM, a potential metastasis suppressor gene in bladder cancer.
Neoplasia (New York, N.Y.) 2002;4(4):291-4.
2002: Christopher H Chay; Carlton C Cooper; Beth A Hellerstedt; Kenneth J Pienta
Antimetastatic drugs in prostate cancer.
Clinical prostate cancer 2002;1(1):14-9.
2002: Beth A Hellerstedt; Kenneth J Pienta
The current state of hormonal therapy for prostate cancer.
CA: a cancer journal for clinicians 2002;52(3):154-79.
2002: Janet Harden; Ann Schafenacker; Laurel L Northouse; Darlene Mood; David C Smith; Kenneth J Pienta; Maha Hussain; Karen Baranowski
Couples' experiences with prostate cancer: focus group research.
Oncology nursing forum 2002;29(4):701-9.
2002: Carlton R Cooper; Christopher H Chay; Kenneth J Pienta
The role of alpha(v)beta(3) in prostate cancer progression.
Neoplasia (New York, N.Y.) 2002;4(3):191-4.
2002: Beth A Hellerstedt; Kenneth J Pienta
Testicular cancer.
Current opinion in oncology 2002;14(3):260-4.
2002: Amy V Gerstein; Teresa Acosta Almeida; Guojing Zhao; Eric Chess; Ie-Ming Shih; Kent R Buhler; Kenneth J Pienta; Mark A Rubin; Robert L Vessella; Nickolas Papadopoulos
APC/CTNNB1 (beta-catenin) pathway alterations in human prostate cancers.
Genes, chromosomes & cancer 2002;34(1):9-16.
2002: Mark A Rubin; Ming Zhou; Saravana M Dhanasekaran; Sooryanarayana Lnu; Terrence barrette; Martin G Sanda; Kenneth J Pienta; Debashis Ghosh; Arul M Chinnaiyan
alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer.
JAMA : the journal of the American Medical Association 2002;287(13):1662-70.
2002: Mark A Moyad; Kenneth J Pienta
Mind-body effect: insulinlike growth factor-1; clinical depression; and breast, prostate, and other cancer risk-an unmeasured and masked mediator of potential significance?
Urology 2002;59(4 Suppl 1):4-8.
2002: Russell Taichman; Carlton Cooper; Evan T Keller; Kenneth J Pienta; Norton S Taichman; Laurie K McCauley
Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone.
Cancer research 2002;62(6):1832-7.
2002: Mark A Rubin; Rodney Dunn; Myla S Strawderman; Kenneth J Pienta
Tissue microarray sampling strategy for prostate cancer biomarker analysis.
The American journal of surgical pathology 2002;26(3):312-9.
2002: Carlton R Cooper; Christopher H Chay; Kenneth J Pienta
New discoveries in prostate cancer biology and treatment. 5-9 December 2001, Naples, Florida, USA.
Expert opinion on therapeutic targets 2002;6(1):123-7.
2002: Carlton R Cooper; Jasmine K Bhatia; Heather J Muenchen; Lisa McLean; Satoru Hayasaka; Jeremy Taylor; Paul J Poncza; Kenneth J Pienta
The regulation of prostate cancer cell adhesion to human bone marrow endothelial cell monolayers by androgen dihydrotestosterone and cytokines.
Clinical & experimental metastasis 2002;19(1):25-33.
2001: Saravana M Dhanasekaran; Terrence barrette; Debashis Ghosh; Rajal B Shah; Sooryanarayana Lnu; Kotoku Kurachi; Kenneth J Pienta; Mark A Rubin; Arul M Chinnaiyan
Delineation of prognostic biomarkers in prostate cancer.
Nature 2001;412(6849):822-6.
2001: Kenneth J Pienta
Preclinical mechanisms of action of docetaxel and docetaxel combinations in prostate cancer.
Seminars in oncology 2001;28(4 Suppl 15):3-7.
2001: Mark A Rubin; NR Mucci; J Figurski; A Fecko; Kenneth J Pienta; Mark Day
E-cadherin expression in prostate cancer: a broad survey using high-density tissue microarray technology.
Human pathology 2001;32(7):690-7.
2001: Hidayatullah Munshi; Kenneth J Pienta; David C Smith
Chemotherapy in patients with prostate specific antigen-only disease after primary therapy for prostate carcinoma: a phase II trial of oral estramustine and oral etoposide.
Cancer 2001;91(11):2175-80.
2001: Susan Korenchuk; jeffrey lehr; L MClean; Young-Goo Lee; S Whitney; R Vessella; D L Lin; Kenneth J Pienta
VCaP, a cell-based model system of human prostate cancer.
In vivo (Athens, Greece) 2001;15(2):163-8.
2001: Young-Goo Lee; Susan Korenchuk; jeffrey lehr; S Whitney; R Vessela; Kenneth J Pienta
Establishment and characterization of a new human prostatic cancer cell line: DuCaP.
In vivo (Athens, Greece) 2001;15(2):157-62.
2001: Kenneth J Pienta; E I Fisher; Mario A Eisenberger; G M Mills; J Wendall Goodwin; Jeffrey A Jones; Shaker R Dakhil; E David Crawford; Maha Hussain
A phase II trial of estramustine and etoposide in hormone refractory prostate cancer: A Southwest Oncology Group trial (SWOG 9407).
The Prostate 2001;46(4):257-61.
2001: Heather J Muenchen; Paul J Poncza; Kenneth J Pienta
Different docetaxel-induced apoptotic pathways are present in prostate cancer cell lines LNCaP and PC-3.
Urology 2001;57(2):366-70.
2001: Kenneth J Pienta; J F Williams
Detection of apoptosis in renal cell carcinoma.
Methods in molecular medicine 2001;53():95-100.
2001: Evan T Keller; Jian Zhang; Carlton R Cooper; P C Smith; Laurie K McCauley; Kenneth J Pienta; Russell Taichman
Prostate carcinoma skeletal metastases: cross-talk between tumor and bone.
Cancer metastasis reviews 2001;20(3-4):333-49.
2001: J Ajani; David S Ettinger; David P Kelsen; Clifford Hudis; A Kudelka; C Langer; Kenneth J Pienta; H Safran; E E Vokes; W K Yung
Radiation Therapy Oncology Group. Research Plan 2002-2006. Medical Oncology Committee.
International journal of radiation oncology, biology, physics 2001;51(3 Suppl 2):88-91.
2001: P Okunieff; E Hammond; David Grignon; C Langer; T F Pajak; K Ang; Deborah Watkins-Bruner; E Travis; K Greven; A Guha; John Moulder; Alan Pollack; Charles Scarantino; N Sneige; J Watson; Mahul B Amin; M Bondy; Arnab Chakravarti; J D Chapman; A Dicker; J Harris; W Koch; R Komaki; C Lange; W McBride; J Mitchell; L Milas; Benjamin Movsas; K Pandya; Kenneth J Pienta; William F Regine; Mark A Ritter; P Rubin; H Safran; E Sauter; M Schell; C Stevens; A Trotti; B Vikram
Radiation Therapy Oncology Group. Research Plan 2002-2006. Translational Research Program.
International journal of radiation oncology, biology, physics 2001;51(3 Suppl 2):75-87.
2001: Howard Sandler; William U Shipley; Leonard G Gomella; Kenneth J Pienta; R H Bard; Deborah Watkins-Bruner; R Clark; Michelle DeSilvio; L Gaspar; Michael T Gillin; David Grignon; Elizabeth Hammond; Gerald Hanks; Kateri Heydon; Donald S Kaufman; W Robert Lee; Jeff Michalski; Jack H Mydlo; Thomas M Pisansky; Alan Pollack; HA Porterfield; M Rifkin; Mack Roach; Martin G Sanda; Lawrence True; Srinivasan Vijayakumar; Kathryn A Winter; A Zeitman
Radiation Therapy Oncology Group. Research Plan 2002-2006. Genitourinary Cancer Committee.
International journal of radiation oncology, biology, physics 2001;51(3 Suppl 2):28-38.
2000: NR Mucci; Mark A Rubin; Myla S Strawderman; James E Montie; David C Smith; Kenneth J Pienta
Expression of nuclear antigen Ki-67 in prostate cancer needle biopsy and radical prostatectomy specimens.
Journal of the National Cancer Institute 2000;92(23):1941-2.
2000: Carlton R Cooper; Lisa McLean; M Walsh; Jeremy Taylor; Satoru Hayasaka; Jasmine K Bhatia; Kenneth J Pienta
Preferential adhesion of prostate cancer cells to bone is mediated by binding to bone marrow endothelial cells as compared to extracellular matrix components in vitro.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(12):4839-47.
2000: Carlton R Cooper; Lisa McLean; NR Mucci; Paul J Poncza; Kenneth J Pienta
Prostate cancer cell adhesion to quiescent endothelial cells is not mediated by beta-1 integrin subunit.
Anticancer research 2000;20(6B):4159-62.
2000: Karin B Olson; Kenneth J Pienta
Use of bisphosphonates in the treatment of prostate cancer.
Oncology (Williston Park, N.Y.) 2000;14(9):1361-4; discussion 1364-7.
2000: Jeffrey F Williams; Heather J Muenchen; Jeffrey M Kamradt; Susan Korenchuk; Kenneth J Pienta
Treatment of androgen-independent prostate cancer using antimicrotubule agents docetaxel and estramustine in combination: an experimental study.
The Prostate 2000;44(4):275-8.
2000: Jill A Macoska; Ben Beheshti; Johng S Rhim; Bharati Hukku; jeffrey lehr; Kenneth J Pienta; Jeremy A Squire
Genetic characterization of immortalized human prostate epithelial cell cultures. Evidence for structural rearrangements of chromosome 8 and i(8q) chromosome formation in primary tumor-derived cells.
Cancer genetics and cytogenetics 2000;120(1):50-7.
2000: Tracy S Schwab; T Stewart; jeffrey lehr; Kenneth J Pienta; Johng S Rhim; Jill A Macoska
Phenotypic characterization of immortalized normal and primary tumor-derived human prostate epithelial cell cultures.
The Prostate 2000;44(2):164-71.
2000: R A Pacis; MJ Pilat; Kenneth J Pienta; K Wojno; Avraham Raz; V Hogan; Carlton R Cooper
Decreased galectin-3 expression in prostate cancer.
The Prostate 2000;44(2):118-23.
2000: Joanne N Davis; Nasima Muqim; Mohammad Bhuiyan; Omer Kucuk; Kenneth J Pienta; Asfar S Azmi
Inhibition of prostate specific antigen expression by genistein in prostate cancer cells.
International journal of oncology 2000;16(6):1091-7.
2000: Karin B Olson; Kenneth J Pienta
Recent advances in chemotherapy for advanced prostate cancer.
Current urology reports 2000;1(1):48-56.
2000: Heather J Muenchen; D L Lin; M A Walsh; Evan T Keller; Kenneth J Pienta
Tumor necrosis factor-alpha-induced apoptosis in prostate cancer cells through inhibition of nuclear factor-kappaB by an IkappaBalpha "super-repressor".
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1969-77.
2000: Heather J Muenchen; M M Quigley; MJ Pilat; jeffrey lehr; S K Brumfield; M Mahoney; Kenneth J Pienta
The study of gemcitabine in combination with other chemotherapeutic agents as an effective treatment for prostate cancer.
Anticancer research 2000;20(2A):735-40.
2000: Mark A Rubin; MJ Putzi; NR Mucci; David C Smith; Kirk J Wojno; Susan Korenchuk; Kenneth J Pienta
Rapid ("warm") autopsy study for procurement of metastatic prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):1038-45.
2000: Pratima Nangia-Makker; Yuichiro Honjo; R Sarvis; Shiro Akahani; Victor Hogan; Kenneth J Pienta; Avraham Raz
Galectin-3 induces endothelial cell morphogenesis and angiogenesis.
The American journal of pathology 2000;156(3):899-909.
2000: Kenneth J Pienta; ED Schwab
Modified differential display technique that eliminates radioactivity and decreases screening time.
BioTechniques 2000;28(2):272-4, 276-7.
2000: Donna L Livant; RK Brabec; Kenneth J Pienta; David L Allen; Kotoku Kurachi; Sonja M Markwart; A Upadhyaya
Anti-invasive, antitumorigenic, and antimetastatic activities of the PHSCN sequence in prostate carcinoma.
Cancer research 2000;60(2):309-20.
2000: Christopher H Chay; Kenneth J Pienta
Evidence for lectin signaling to the nuclear matrix: cellular interpretation of the glycocode.
Journal of cellular biochemistry. Supplement 2000;Suppl 35():123-9.
2000: Jeffrey M Kamradt; Kenneth J Pienta
Etoposide in prostate cancer.
Expert opinion on pharmacotherapy 2000;1(2):271-5.
2000: George J Brewer; Robert D Dick; D K Grover; V LeClaire; M Tseng; Max S Wicha; Kenneth J Pienta; Bruce G Redman; Thierry jahan; vernon sondak; Myla S Strawderman; Gerald L LeCarpentier; Sofia D Merajver
Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: Phase I study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(1):1-10.
1999: KM Dougherty; Eric A G Blomme; Amy J Koh; J E Henderson; Kenneth J Pienta; Thomas J Rosol; Laurie K McCauley
Parathyroid hormone-related protein as a growth regulator of prostate carcinoma.
Cancer research 1999;59(23):6015-22.
1999: M H Eng; LG Charles; Brian D Ross; Clarence Chrisp; Kenneth J Pienta; N M Greenberg; CX Hsu; Martin G Sanda
Early castration reduces prostatic carcinogenesis in transgenic mice.
Urology 1999;54(6):1112-9.
1999: Peg Esper; J N Hampton; J Finn; David C Smith; S Regiani; Kenneth J Pienta
A new concept in cancer care: the supportive care program.
The American journal of hospice & palliative care 1999;16(6):713-22.
1999: Karin B Olson; Kenneth J Pienta
Pain management in patients with advanced prostate cancer.
Oncology (Williston Park, N.Y.) 1999;13(11):1537-49; discussion 1549-50 passim.
1999: R Panvichian; K Orth; MJ Pilat; Mark Day; Kathleen C Day; C Yee; Jeffrey M Kamradt; Kenneth J Pienta
Signaling network of paclitaxel-induced apoptosis in the LNCaP prostate cancer cell line.
Urology 1999;54(4):746-52.
1999: Mark A Moyad; Kenneth J Pienta; James E Montie
Use of PC-SPES, a commercially available supplement for prostate cancer, in a patient with hormone-naive disease.
Urology 1999;54(2):319-23; discussion 323-4.
1999: David C Smith; Peg Esper; Myla S Strawderman; Bruce G Redman; Kenneth J Pienta
Phase II trial of oral estramustine, oral etoposide, and intravenous paclitaxel in hormone-refractory prostate cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(6):1664-71.
1999: James E Montie; Kenneth J Pienta
A unifying model to explain the increased incidence and higher mortality of prostate cancer in black men.
Urology 1999;53(6):1073-6.
1999: Eric A G Blomme; KM Dougherty; Kenneth J Pienta; Charles C Capen; Thomas J Rosol; Laurie K McCauley
Skeletal metastasis of prostate adenocarcinoma in rats: morphometric analysis and role of parathyroid hormone-related protein.
The Prostate 1999;39(3):187-97.
1999: Jeffrey M Kamradt; David C Smith; Kenneth J Pienta
Oral chemotherapy for hormone refractory prostate cancer. The University of Michigan experience.
The Urologic clinics of North America 1999;26(2):333-40.
1999: Jeffrey M Kamradt; E A Klein; Kenneth J Pienta
Rational use of chemotherapy. It is not just rat poison.
The Urologic clinics of North America 1999;26(2):275-9, vii.
1999: Mark A Moyad; S K Brumfield; Kenneth J Pienta
Vitamin E, alpha- and gamma-tocopherol, and prostate cancer.
Seminars in urologic oncology 1999;17(2):85-90.
1999: Jeffrey M Kamradt; Kenneth J Pienta
Novel molecular targets for prostate cancer therapy.
Seminars in oncology 1999;26(2):234-43.
1999: David C Smith; Kenneth J Pienta
Paclitaxel in the treatment of hormone-refractory prostate cancer.
Seminars in oncology 1999;26(1 Suppl 2):109-11.
1999: Martin G Sanda; David C Smith; LG Charles; C Hwang; Kenneth J Pienta; J Schlom; D Milenic; D Panicali; James E Montie
Recombinant vaccinia-PSA (PROSTVAC) can induce a prostate-specific immune response in androgen-modulated human prostate cancer.
Urology 1999;53(2):260-6.
1999: Kenneth J Pienta; Jeffrey M Kamradt; David C Smith
Oral chemotherapy in the treatment of hormone-refractory prostate cancer.
Drugs 1999;58 Suppl 3():127-31.
1999: Heather J Muenchen; Kenneth J Pienta
The role of the nuclear matrix in cancer chemotherapy.
Critical reviews in eukaryotic gene expression 1999;9(3-4):337-43.
1999: Peg Esper; J N Hampton; David C Smith; Kenneth J Pienta
Quality-of-life evaluation in patients receiving treatment for advanced prostate cancer.
Oncology nursing forum 1999;26(1):107-12.
1998: jeffrey lehr; MJ Pilat; Kenneth J Pienta
The isolation and characterization of epithelial cells from canine prostate.
Anticancer research 1998;18(6A):4483-8.
1998: Christina S K Yee; Jeffrey M Kamradt; L C Nielsen; R Panvinchian; Kenneth J Pienta
Carboplatin-induced cell death in model prostate cancer systems.
Anticancer research 1998;18(6A):4475-82.
1998: R Panvichian; K Orth; Mark Day; Kathleen C Day; MJ Pilat; Kenneth J Pienta
Paclitaxel-associated multimininucleation is permitted by the inhibition of caspase activation: a potential early step in drug resistance.
Cancer research 1998;58(20):4667-72.
1998: CX Hsu; Brian D Ross; Clarence Chrisp; S Z Derrow; LG Charles; Kenneth J Pienta; N M Greenberg; Z Zeng; Martin G Sanda
Longitudinal cohort analysis of lethal prostate cancer progression in transgenic mice.
The Journal of urology 1998;160(4):1500-5.
1998: ED Schwab; Daniel Normolle; R A Pacis; S S Cho; Kenneth J Pienta
A high-fat diet does not influence the growth of the Dunning R3327-H transplantable prostate adenocarcinoma.
Anticancer research 1998;18(5A):3603-7.
1998: jeffrey lehr; Kenneth J Pienta; K Yamazaki; MJ Pilat
A model to study c-myc and v-H-ras induced prostate cancer progression in the Copenhagen rat.
Cellular and molecular biology (Noisy-le-Grand, France) 1998;44(6):949-59.
1998: David C Smith; Bruce G Redman; Lawrence E Flaherty; L Li; Myla S Strawderman; Kenneth J Pienta
A phase II trial of oral diethylstilbesterol as a second-line hormonal agent in advanced prostate cancer.
Urology 1998;52(2):257-60.
1998: MJ Pilat; ED Schwab; K L Yao; Kenneth J Pienta
Examination of the DNA methylation properties in nontumorigenic and tumorigenic breast epithelial cell lines.
Anticancer research 1998;18(4A):2575-82.
1998: Jeffrey M Kamradt; Kenneth J Pienta
The effect of hydrazine sulfate on prostate cancer growth.
Oncology reports 1998;5(4):919-21.
1998: MJ Pilat; jeffrey lehr; M M Quigley; Kenneth J Pienta
The effect of amiloride on the metastatic properties of prostate cancer in the Dunning rat model.
Oncology reports 1998;5(4):889-92.
1998: David C Smith; Rodney L Dunn; Myla S Strawderman; Kenneth J Pienta
Change in serum prostate-specific antigen as a marker of response to cytotoxic therapy for hormone-refractory prostate cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(5):1835-43.
1998: K B Olson; Kenneth J Pienta
Vitamins A and E: further clues for prostate cancer prevention.
Journal of the National Cancer Institute 1998;90(6):414-5.
1998: jeffrey lehr; Kenneth J Pienta
Preferential adhesion of prostate cancer cells to a human bone marrow endothelial cell line.
Journal of the National Cancer Institute 1998;90(2):118-23.
1998: MJ Pilat; Jeffrey M Kamradt; Kenneth J Pienta
Hormone resistance in prostate cancer.
Cancer metastasis reviews 1998;17(4):373-81.
1997: Peg Esper; F Mo; Gerald Chodak; Michael Sinner; David Cella; Kenneth J Pienta
Measuring quality of life in men with prostate cancer using the functional assessment of cancer therapy-prostate instrument.
Urology 1997;50(6):920-8.
1997: T S Replogle-Schwab; ED Schwab; Kenneth J Pienta
Development of doxorubicin resistant rat prostate cancer cell lines.
Anticancer research 1997;17(6D):4535-8.
1997: Kenneth J Pienta; David C Smith
Paclitaxel, estramustine, and etoposide in the treatment of hormone-refractory prostate cancer.
Seminars in oncology 1997;24(5 Suppl 15):S15-72-S15-77.
1997: Christina S K Yee; ED Schwab; jeffrey lehr; M Quigley; Kenneth J Pienta
The effect of castanospermine on the metastatic properties of prostate cancer cells.
Anticancer research 1997;17(5A):3659-63.
1997: Kenneth J Pienta; Bruce G Redman; R Bandekar; Myla S Strawderman; Kemp B Cease; Peg Esper; H Naik; David C Smith
A phase II trial of oral estramustine and oral etoposide in hormone refractory prostate cancer.
Urology 1997;50(3):401-6; discussion 406-7.
1997: David C Smith; Kenneth J Pienta
The use of prostate-specific antigen as a surrogate end point in the treatment of patients with hormone refractory prostate cancer.
The Urologic clinics of North America 1997;24(2):433-7.
1997: ED Schwab; Kenneth J Pienta
Modeling signal transduction in normal and cancer cells using complex adaptive systems.
Medical hypotheses 1997;48(2):111-23.
1997: Peg Esper; Kenneth J Pienta
Supportive care in the patient with hormone refractory prostate cancer.
Seminars in urologic oncology 1997;15(1):56-64.
1997: Kenneth J Pienta; Peg Esper; Fred Zwas; R Krzeminski; Lawrence E Flaherty
Phase II chemoprevention trial of oral fenretinide in patients at risk for adenocarcinoma of the prostate.
American journal of clinical oncology 1997;20(1):36-9.
1996: Kenneth J Pienta; J A Goodson; Peg Esper
Epidemiology of prostate cancer: molecular and environmental clues.
Urology 1996;48(5):676-83.
1996: Kenneth J Pienta; Bruce G Redman; Peg Esper; Lawrence E Flaherty
A phase II evaluation of oral tamoxifen and intermittent intravenous vinblastine in hormone-refractory adenocarcinoma of the prostate.
American journal of clinical oncology 1996;19(5):500-3.
1996: ED Schwab; Kenneth J Pienta
Cancer as a complex adaptive system.
Medical hypotheses 1996;47(3):235-41.
1996: H Naik; jeffrey lehr; Kenneth J Pienta
Inhibition of prostate cancer growth by 9-aminocamptothecin and estramustine.
Urology 1996;48(3):508-11.
1996: K Yamazaki; T Replogleschwab; Kenneth J Pienta
Nuclear matrix protein composition of human lung carcinoma cell lines.
Oncology reports 1996;3(4):737-41.
1996: K Yamazaki; jeffrey lehr; J S Rhim; Kenneth J Pienta
Establishment of an immortalized Copenhagen rat bone marrow endothelial cell line.
In vivo (Athens, Greece) 1996;10(4):459-62.
1996: T S Replogle-Schwab; Robert H Getzenberg; T L Donat; Kenneth J Pienta
Effect of organ site on nuclear matrix protein composition.
Journal of cellular biochemistry 1996;62(1):132-41.
1996: Kenneth J Pienta; H Naik; jeffrey lehr
Effect of estramustine, etoposide, and taxol on prostate cancer cell growth in vitro and in vivo.
Urology 1996;48(1):164-70.
1996: P K Pandalai; MJ Pilat; K Yamazaki; H Naik; Kenneth J Pienta
The effects of omega-3 and omega-6 fatty acids on in vitro prostate cancer growth.
Anticancer research 1996;16(2):815-20.
1996: T L Donat; Wael A Sakr; jeffrey lehr; Kenneth J Pienta
Unique nuclear matrix protein alterations in head and neck squamous cell carcinomas: intermediate biomarker candidates.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1996;114(3):387-93.
1996: R Panvichian; Kenneth J Pienta
The treatment of hormone refractory prostate cancer.
Comprehensive therapy 1996;22(2):81-7.
1996: Kenneth J Pienta; Peg Esper; H Naik; J Parzuchowski; J Bellefleur
The Hospice Supportive Care Program: a new "transitionless" model of palliative care for patients with incurable prostate cancer.
Journal of the National Cancer Institute 1996;88(1):55-6.
1996: K L Yao; MJ Pilat; Kenneth J Pienta
Reverse transcriptase- polymerase chain reaction (RT-PCR) to detect prostate cancer micrometastasis in the blood.
Cancer treatment and research 1996;88():77-91.
1996: R Replogle-Schwab; Kenneth J Pienta; Robert H Getzenberg
The utilization of nuclear matrix proteins for cancer diagnosis.
Critical reviews in eukaryotic gene expression 1996;6(2-3):103-13.
1996: T S Replogle; Kenneth J Pienta
Role of the nuclear matrix in breast cancer.
Cancer treatment and research 1996;83():127-40.
1995: L Wang; H Inohara; Kenneth J Pienta; Avraham Raz
Galectin-3 is a nuclear matrix protein which binds RNA.
Biochemical and biophysical research communications 1995;217(1):292-303.
1995: R Pacis; M Pilat; K Yamazaki; Kenneth J Pienta
Differential carbohydrate expression in tumorigenic vs nontumorigenic prostate cell-lines.
International journal of oncology 1995;7(6):1349-54.
1995: T Fregene; C Kellogg; Kenneth J Pienta
Microvessel quantification as a measure of angiogenic activity in benign breast-tissue lesions - a marker for precancerous disease.
Oncology reports 1995;2(6):1181-4.
1995: Steven A. Silletti; J P Yao; Kenneth J Pienta; Avraham Raz
Loss of cell-contact regulation and altered responses to autocrine motility factor correlate with increased malignancy in prostate cancer cells.
International journal of cancer. Journal international du cancer 1995;63(1):100-5.
1995: T Donat; Wael A Sakr; Kenneth J Pienta
Nuclear morphometry for predicting cervical metastatic potential in laryngeal squamous-cell carcinoma.
International journal of oncology 1995;7(3):673-7.
1995: K Yamazaki; Kenneth J Pienta
Establishment of an immortalized Copenhagen rat prostate epithelial cell line.
In vivo (Athens, Greece) 1995;9(5):427-32.
1995: K Yamazaki; jeffrey lehr; J S Rhim; Kenneth J Pienta
Establishment of immortalized Copenhagen rat prostate endothelial cell lines.
In vivo (Athens, Greece) 1995;9(5):421-6.
1995: Marwan G Fakih; A Yagoda; T Replogle; jeffrey lehr; Kenneth J Pienta
Inhibition of prostate cancer growth by estramustine and colchicine.
The Prostate 1995;26(6):310-5.
1995: Kenneth J Pienta; T Replogle; jeffrey lehr
Inhibition of prostate cancer growth by vinblastine and tamoxifen.
The Prostate 1995;26(5):270-4.
1995: Bruce G Redman; Kenneth J Pienta
New treatment strategies for hormone refractory prostate cancer.
Seminars in urology 1995;13(2):164-9.
1995: Kenneth J Pienta; H Naik; A Akhtar; K Yamazaki; T S Replogle; jeffrey lehr; T L Donat; Larry Tait; V Hogan; Avraham Raz
Inhibition of spontaneous metastasis in a rat prostate cancer model by oral administration of modified citrus pectin.
Journal of the National Cancer Institute 1995;87(5):348-53.
1995: H Naik; D Petrylak; A Yagoda; J Lehr; A Akhtar; Kenneth J Pienta
Preclinical studies of gossypol in prostate carcinoma.
International journal of oncology 1995;6(1):209-13.
1995: R Krzeminski; Fred Zwas; Peg Esper; Kenneth J Pienta
Electroretinographic findings in subjects after administration of fenretinide.
Documenta ophthalmologica. Advances in ophthalmology 1995;91(4):299-309.
1995: Kenneth J Pienta; R Demers; M Hoff; T Y Kau; James E Montie; Richard K Severson
Effect of age and race on the survival of men with prostate cancer in the Metropolitan Detroit tricounty area, 1973 to 1987.
Urology 1995;45(1):93-101; discussion 101-2.
1995: H R Naik; Gregory P Kalemkerian; Kenneth J Pienta
4-Hydroxyphenylretinamide in the chemoprevention of cancer.
Advances in pharmacology (San Diego, Calif.) 1995;33():315-47.
1994: T Fregene; P Khanuja; P Gimotty; C Kellogg; J George; Kenneth J Pienta
The relationship of microvessel counts to tumor size, estrogen-receptor status, lymph-node metastasis, and disease-free survival in patients with stage-I and stage-ii breast-cancer.
International journal of oncology 1994;5(6):1437-45.
1994: Jill A Macoska; C N Hoover; Kenneth J Pienta
Alterations in cellular gene expression without changes in nuclear matrix protein content.
Journal of cellular biochemistry 1994;56(4):502-9.
1994: H Naik; jeffrey lehr; A Akhtar; Kenneth J Pienta
Oral cyclophosphamide and oral hydroxyurea in the treatment of hormone refractory prostate cancer in rats.
Anticancer research 1994;14(6B):2681-4.
1994: H R Naik; jeffrey lehr; Kenneth J Pienta
An in vitro and in vivo study of antitumor effects of genistein on hormone refractory prostate cancer.
Anticancer research 1994;14(6B):2617-9.
1994: jeffrey lehr; K Yamazaki; J Onoda; Kenneth J Pienta
Immunomagnetic isolation of endothelial cells from normal rat prostate tissue.
In vivo (Athens, Greece) 1994;8(6):983-8.
1994: Kenneth J Pienta; Bruce G Redman; Maha Hussain; G Cummings; Peg Esper; C Appel; Lawrence E Flaherty
Phase II evaluation of oral estramustine and oral etoposide in hormone-refractory adenocarcinoma of the prostate.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(10):2005-12.
1994: Maha Hussain; Kenneth J Pienta; Bruce G Redman; G D Cummings; Lawrence E Flaherty
Oral etoposide in the treatment of hormone-refractory prostate cancer.
Cancer 1994;74(1):100-3.
1994: T Fregene; C Kellogg; Kenneth J Pienta
Microvessel quantification as a measure of angiogenic activity in benign breast tissues lesions - a marker for precancerous disease.
International journal of oncology 1994;4(6):1199-202.
1994: James E Montie; Kenneth J Pienta
Review of the role of androgenic hormones in the epidemiology of benign prostatic hyperplasia and prostate cancer.
Urology 1994;43(6):892-9.
1994: Kenneth J Pienta; C N Hoover
Coupling of cell structure to cell metabolism and function.
Journal of cellular biochemistry 1994;55(1):16-21.
1994: Kenneth J Pienta
The epidemiology of prostate cancer: clues for chemoprevention.
In vivo (Athens, Greece) 1994;8(3):419-22.
1994: Kenneth J Pienta; W S Ward
An unstable nuclear matrix may contribute to genetic instability.
Medical hypotheses 1994;42(1):45-52.
1993: T A Fregene; P S Khanuja; A C Noto; S K Gehani; E M Van Egmont; D A Luz; Kenneth J Pienta
Tumor-associated angiogenesis in prostate cancer.
Anticancer research 1993;13(6B):2377-81.
1993: N M Nguyen; jeffrey lehr; Kenneth J Pienta
Pentosan inhibits angiogenesis in vitro and suppresses prostate tumor growth in vivo.
Anticancer research 1993;13(6A):2143-7.
1993: N M Nguyen; jeffrey lehr; C I Shelley; Judith C Andersen; Kenneth J Pienta
The effect of maltose tetrapalmitate (MTP) on prostate cancer growth in vivo and in vitro.
Anticancer research 1993;13(6A):2053-8.
1993: Kenneth J Pienta; P S Esper
Is dietary fat a risk factor for prostate cancer?
Journal of the National Cancer Institute 1993;85(19):1538-40.
1993: Seema Garde; A R Sheth; AT Porter; Kenneth J Pienta
A comparative study on expression of prostatic inhibin peptide, prostate acid phosphatase and prostate specific antigen in androgen independent human and rat prostate carcinoma cell lines.
Cancer letters 1993;70(3):159-66.
1993: P S Khanuja; jeffrey lehr; H D Soule; S K Gehani; A C Noto; S Choudhury; R Chen; Kenneth J Pienta
Nuclear matrix proteins in normal and breast cancer cells.
Cancer research 1993;53(14):3394-8.
1993: Kenneth J Pienta; jeffrey lehr
Inhibition of prostate cancer growth by estramustine and etoposide: evidence for interaction at the nuclear matrix.
The Journal of urology 1993;149(6):1622-5.
1993: Kenneth J Pienta; Peg Esper
Risk factors for prostate cancer.
Annals of internal medicine 1993;118(10):793-803.
1993: Kenneth J Pienta; N M Nguyen; jeffrey lehr
Treatment of prostate cancer in the rat with the synthetic retinoid fenretinide.
Cancer research 1993;53(2):224-6.
1993: Seema Garde; A Sheth; AT Porter; Kenneth J Pienta
Effect of prostatic inhibin peptide (PIP) on prostate cancer cell growth in vitro and in vivo.
The Prostate 1993;22(3):225-33.
1993: Kenneth J Pienta; jeffrey lehr
A common set of nuclear matrix proteins in prostate cancer cells.
The Prostate 1993;23(1):61-7.
1992: Kenneth J Pienta; Donald S Coffey
Nuclear-cytoskeletal interactions: evidence for physical connections between the nucleus and cell periphery and their alteration by transformation.
Journal of cellular biochemistry 1992;49(4):357-65.
1992: O M Karim; Kenneth J Pienta; N Seki; Jacek L Mostwin
Stretch-mediated visceral smooth muscle growth in vitro.
The American journal of physiology 1992;262(5 Pt 2):R895-900.
1992: R J Briggs; Kenneth J Pienta; Ralph Hruban; WJ Richtsmeier
Nuclear morphometry for prediction of metastatic potential in early squamous cell carcinoma of the floor of the mouth.
Archives of otolaryngology--head & neck surgery 1992;118(5):531-3.
1992: O M Karim; N Seki; Kenneth J Pienta; Jacek L Mostwin
The effect of age on the response of the detrusor to intracellular mechanical stimulus: DNA replication and the cell actin matrix.
Journal of cellular biochemistry 1992;48(4):373-84.
1992: Kenneth J Pienta; Robert H Getzenberg; Donald S Coffey
Characterization of nuclear morphology and nuclear matrices in ageing human fibroblasts.
Mechanisms of ageing and development 1992;62(1):13-24.
1992: Kenneth J Pienta; B C Murphy; William B Isaacs; John T Isaacs; Donald S Coffey
Effect of pentosan, a novel cancer chemotherapeutic agent, on prostate cancer cell growth and motility.
The Prostate 1992;20(3):233-41.
1992: B C Murphy; Kenneth J Pienta; Donald S Coffey
Effects of extracellular matrix components and dihydrotestosterone on the structure and function of human prostate cancer cells.
The Prostate 1992;20(1):29-41.
1991: Robert H Getzenberg; Kenneth J Pienta; E Y Huang; Donald S Coffey
Identification of nuclear matrix proteins in the cancer and normal rat prostate.
Cancer research 1991;51(24):6514-20.
1991: Robert H Getzenberg; Kenneth J Pienta; W S Ward; Donald S Coffey
Nuclear structure and the three-dimensional organization of DNA.
Journal of cellular biochemistry 1991;47(4):289-99.
1991: Kenneth J Pienta; Donald S Coffey
Correlation of nuclear morphometry with progression of breast cancer.
Cancer 1991;68(9):2012-6.
1991: Robert H Getzenberg; Kenneth J Pienta; E Y Huang; B C Murphy; Donald S Coffey
Modifications of the intermediate filament and nuclear matrix networks by the extracellular matrix.
Biochemical and biophysical research communications 1991;179(1):340-4.
1991: Kenneth J Pienta; B C Murphy; Robert H Getzenberg; Donald S Coffey
The effect of extracellular matrix interactions on morphologic transformation in vitro.
Biochemical and biophysical research communications 1991;179(1):333-9.
1991: J Boyd; Kenneth J Pienta; Robert H Getzenberg; Donald S Coffey; J Carl Barrett
Preneoplastic alterations in nuclear morphology that accompany loss of tumor suppressor phenotype.
Journal of the National Cancer Institute 1991;83(12):862-6.
1991: Kenneth J Pienta; Donald S Coffey
Cellular harmonic information transfer through a tissue tensegrity-matrix system.
Medical hypotheses 1991;34(1):88-95.
1991: Kenneth J Pienta; William B Isaacs; D Vindivich; Donald S Coffey
The effects of basic fibroblast growth factor and suramin on cell motility and growth of rat prostate cancer cells.
The Journal of urology 1991;145(1):199-202.
1991: Kenneth J Pienta; Robert H Getzenberg; Donald S Coffey
Cell structure and DNA organization.
Critical reviews in eukaryotic gene expression 1991;1(4):355-85.
1991: Kenneth J Pienta; Donald S Coffey
Cell motility as a chemotherapeutic target.
Cancer surveys 1991;11():255-63.
1990: Kenneth J Pienta; Donald S Coffey
Characterization of the subtypes of cell motility in ageing human skin fibroblasts.
Mechanisms of ageing and development 1990;56(2):99-105.
1990: Robert H Getzenberg; Kenneth J Pienta; Donald S Coffey
The tissue matrix: cell dynamics and hormone action.
Endocrine reviews 1990;11(3):399-417.
1989: Kenneth J Pienta; Alan W Partin; Donald S Coffey
Cancer as a disease of DNA organization and dynamic cell structure.
Cancer research 1989;49(10):2525-32.
1988: B Glaser; G Zoghlin; Kenneth J Pienta; A I Vinik
Pancreatic polypeptide response to secretin in obesity: effects of glucose intolerance.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1988;20(5):288-92.
1987: Donald S Coffey; Kenneth J Pienta
New concepts in studying the control of normal and cancer growth of the prostate.
Progress in clinical and biological research 1987;239():1-73.
1986: William G Nelson; Kenneth J Pienta; Evelyn Barrack; Donald S Coffey
The role of the nuclear matrix in the organization and function of DNA.
Annual review of biophysics and biophysical chemistry 1986;15():457-75.
1984: Kenneth J Pienta; Donald S Coffey
A structural analysis of the role of the nuclear matrix and DNA loops in the organization of the nucleus and chromosome.
Journal of cell science. Supplement 1984;1():123-35.
1981: B Shapiro; Kenneth J Pienta; A Heldsinger; A I Vinik
Somatostatin is an agonist and noncompetitive antagonist of gastrin in oxyntic cell function.
Endocrinology 1981;109(4):1117-21.
1981: Akira Arimura; Kate Groot; T Taminato; A Ertan; K Akdamar; J Ryan; Kenneth J Pienta; A I Vinik
Somatostatin in human pancreatic and gastric juice.
Peptides 1981;2 Suppl 2():271-4.