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Grant Pierce

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Andrea L Edel; Michel Aliani; Grant N Pierce
Supported liquid extraction in the quantitation of plasma enterolignans using isotope dilution GC/MS with application to flaxseed consumption in healthy adults.
Mirna N Chahine; Elena Dibrov; David P Blackwood; Grant N Pierce
Oxidized LDL enhances stretch-induced smooth muscle cell proliferation through alterations in nuclear protein import.
Saeid Ghavami; Andrew J Halayko; Morvarid Kavosh; Thomas Klonisch; Marek Los; Grant N Pierce; Sunil G Rattan; Behzad Yeganeh; Krista Bathe; Ryan H Cunnington; Jared J L Davies; Darren H Freed; Ian M C Dixon
Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts.

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2013: Andrea L Edel; Michel Aliani; Grant N Pierce
Supported liquid extraction in the quantitation of plasma enterolignans using isotope dilution GC/MS with application to flaxseed consumption in healthy adults.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2013;912():24-32.
2012: Mirna N Chahine; Elena Dibrov; David P Blackwood; Grant N Pierce
Oxidized LDL enhances stretch-induced smooth muscle cell proliferation through alterations in nuclear protein import.
Canadian journal of physiology and pharmacology 2012;90(12):1559-68.
2012: Saeid Ghavami; Andrew J Halayko; Morvarid Kavosh; Thomas Klonisch; Marek Los; Grant N Pierce; Sunil G Rattan; Behzad Yeganeh; Krista Bathe; Ryan H Cunnington; Jared J L Davies; Darren H Freed; Ian M C Dixon
Autophagy regulates trans fatty acid-mediated apoptosis in primary cardiac myofibroblasts.
Biochimica et biophysica acta 2012;1823(12):2274-86.
2012: Riya Ganguly; Grant N Pierce
Trans fat involvement in cardiovascular disease.
Molecular nutrition & food research 2012;56(7):1090-6.
2012: Tod A Clark; Andrea L Edel; Clayton E Heyliger; Asad Junaid; Hae K Kim; Melanie Kopilas; Michele Merchant; Donald D Smyth; James A Thliveris; Floribeth Aguilar; Grant N Pierce
A tea/vanadate decoction delivered orally over 14 months to diabetic rats induces long-term glycemic stability without organ toxicity.
Metabolism: clinical and experimental 2012;61(5):742-53.
2012: Justin F Deniset; Elena Dibrov; Thomas E Hedley; Grant N Pierce
Chlamydophila pneumoniae infection induces alterations in vascular contractile responses.
The American journal of pathology 2012;180(3):1264-72.
2012: Michel Aliani; Donna Ryland; Grant N Pierce
Effect of flax addition on the flavor profile and acceptability of bagels.
Journal of food science 2012;77(1):S62-70.
2011: Mirna N Chahine; Justin Deniset; Elena Dibrov; Satoru Hirono; J Alejandro Austria; David P Blackwood; Grant N Pierce
Oxidized LDL promotes the mitogenic actions of Chlamydia pneumoniae in vascular smooth muscle cells.
Cardiovascular research 2011;92(3):476-83.
2011: Chantal M C Bassett; Andrea L Edel; Renee K LaVallee; Richelle S McCullough; Amanda Patenaude; Grant N Pierce
The α-linolenic acid content of flaxseed can prevent the atherogenic effects of dietary trans fat.
American journal of physiology. Heart and circulatory physiology 2011;301(6):H2220-6.
2011: Richelle S McCullough; Bradley P Ander; Chantal M C Bassett; David P Blackwood; Elena Dibrov; Andrea L Edel; Renée K Lavallée; Grant N Pierce
The alpha linolenic acid content of flaxseed is associated with an induction of adipose leptin expression.
Lipids 2011;46(11):1043-52.
2011: N T Gavel; M Merchant; C M C Bassett; Andrea L Edel; D Rodriguez-Leyva; A-M Weber; Grant N Pierce
The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits.
Acta physiologica Hungarica 2011;98(3):273-83.
2011: Randolph S Faustino; Thane G Maddaford; Grant N Pierce
Mitogen activated protein kinase at the nuclear pore complex.
Journal of cellular and molecular medicine 2011;15(4):928-37.
2011: Andrew A Francis; Grant N Pierce
An integrated approach for the mechanisms responsible for atherosclerotic plaque regression.
Experimental and clinical cardiology 2011;16(3):77-86.
2010: Tod A Clark; Thane G Maddaford; Paramjit S Tappia; Clayton E Heyliger; Pallab K Ganguly; Grant N Pierce
Restoration of cardiomyocyte function in streptozotocin-induced diabetic rats after treatment with vanadate in a tea decoction.
Current pharmaceutical biotechnology 2010;11(8):906-10.
2010: Bing Xu; Yaling Zhou; Karmin O; Patrick C Choy; Grant N Pierce; Chris Siow
Regulation of stress-associated scaffold proteins JIP1 and JIP3 on the c-Jun NH2-terminal kinase in ischemia-reperfusion.
Canadian journal of physiology and pharmacology 2010;88(11):1084-92.
2010: Justin F Deniset; Grant N Pierce
Possibilities for therapeutic interventions in disrupting Chlamydophila pneumoniae involvement in atherosclerosis.
Fundamental & clinical pharmacology 2010;24(5):607-17.
2010: James S C Gilchrist; Tom Cook; Bernard Abrenica; Babak Rashidkhani; Grant N Pierce
Extensive autolytic fragmentation of membranous versus cytosolic calpain following myocardial ischemia-reperfusion.
Canadian journal of physiology and pharmacology 2010;88(5):584-94.
2010: Bradley P Ander; Andrea L Edel; Richelle McCullough; Delfin Rodriguez-Leyva; Penelope P Rampersad; James S C Gilchrist; Anton Lukas; Grant N Pierce
Distribution of omega-3 fatty acids in tissues of rabbits fed a flaxseed-supplemented diet.
Metabolism: clinical and experimental 2010;59(5):620-7.
2010: Justin F Deniset; Paul K M Cheung; Elena Dibrov; Kaitlin Lee; Sarah Steigerwald; Grant N Pierce
Chlamydophila pneumoniae infection leads to smooth muscle cell proliferation and thickening in the coronary artery without contributions from a host immune response.
The American journal of pathology 2010;176(2):1028-37.
2010: Thane G Maddaford; Elena Dibrov; Cecilia Hurtado; Grant N Pierce
Reduced expression of the Na+/Ca2+ exchanger in adult cardiomyocytes via adenovirally delivered shRNA results in resistance to simulated ischemic injury.
American journal of physiology. Heart and circulatory physiology 2010;298(2):H360-6.
2010: Marjorie E Zettler; Michele A Merchant; Grant N Pierce
Augmented cell cycle protein expression and kinase activity in atherosclerotic rabbit vessels.
Experimental and clinical cardiology 2010;15(4):e139-44.
2010: Delfin Rodriguez-Leyva; Grant N Pierce
The cardiac and haemostatic effects of dietary hempseed.
Nutrition & metabolism 2010;7():32.
2010: Chantal M C Bassett; Andrea L Edel; Amanda F Patenaude; Richelle S McCullough; David P Blackwood; P Yvan Chouinard; Paul Paquin; Benoît Lamarche; Grant N Pierce
Dietary vaccenic acid has antiatherogenic effects in LDLr-/- mice.
The Journal of nutrition 2010;140(1):18-24.
2009: Chantal M C Bassett; Richelle S McCullough; Andrea L Edel; Thane G Maddaford; Elena Dibrov; David P Blackwood; J Alejandro Austria; Grant N Pierce
Trans-fatty acids in the diet stimulate atherosclerosis.
Metabolism: clinical and experimental 2009;58(12):1802-8.
2009: Chantal M C Bassett; Delfin Rodriguez-Leyva; Grant N Pierce
Experimental and clinical research findings on the cardiovascular benefits of consuming flaxseed.
Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme 2009;34(5):965-74.
2009: Mirna N Chahine; Grant N Pierce
Therapeutic targeting of nuclear protein import in pathological cell conditions.
Pharmacological reviews 2009;61(3):358-72.
2009: A Patenaude; D Rodriguez-Leyva; Andrea L Edel; Elena Dibrov; C M C Dupasquier; J Alejandro Austria; Melanie N Richard; M N Chahine; L J Malcolmson; Grant N Pierce
Bioavailability of alpha-linolenic acid from flaxseed diets as a function of the age of the subject.
European journal of clinical nutrition 2009;63(9):1123-9.
2009: Mohammad M Abdullah; Natalie N Riediger; Qilin Chen; Zhaohui Zhao; Nazila Azordegan; Zuyuan Xu; Gabor Fischer; Rgia A Othman; Grant N Pierce; Paramjit S Tappia; Jitao Zou; Mohammed H Moghadasian
Effects of long-term consumption of a high-fructose diet on conventional cardiovascular risk factors in Sprague-Dawley rats.
Molecular and cellular biochemistry 2009;327(1-2):247-56.
2009: Mirna N Chahine; David P Blackwood; Elena Dibrov; Melanie N Richard; Grant N Pierce
Oxidized LDL affects smooth muscle cell growth through MAPK-mediated actions on nuclear protein import.
Journal of molecular and cellular cardiology 2009;46(3):431-41.
2008: Pallab K Ganguly; Thane G Maddaford; Andrea L Edel; Karmin O; John S Smeda; Grant N Pierce
Increased homocysteine-induced release of excitatory amino acids in the striatum of spontaneously hypertensive stroke-prone rats.
Brain research 2008;1226():192-8.
2008: J Alejandro Austria; Melanie N Richard; Mirna N Chahine; Andrea L Edel; Linda J Malcolmson; Chantal Bassett; Grant N Pierce
Bioavailability of alpha-linolenic acid in subjects after ingestion of three different forms of flaxseed.
Journal of the American College of Nutrition 2008;27(2):214-21.
2008: Natalie D Riediger; Rgia Othman; Evelyn Fitz; Grant N Pierce; Miyoung Suh; Mohammed H Moghadasian
Low n-6:n-3 fatty acid ratio, with fish- or flaxseed oil, in a high fat diet improves plasma lipids and beneficially alters tissue fatty acid composition in mice.
European journal of nutrition 2008;47(3):153-60.
2008: M A Prociuk; Andrea L Edel; Melanie N Richard; N T Gavel; Bradley P Ander; Chantal Bassett; Grant N Pierce
Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed-enriched diet.
Canadian journal of physiology and pharmacology 2008;86(4):153-9.
2008: Randolph S Faustino; Paul Cheung; Melanie N Richard; Elena Dibrov; Annette L Kneesch; Justin F Deniset; Mirna N Chahine; Kaitlin Lee; David Blackwood; Grant N Pierce
Ceramide regulation of nuclear protein import.
Journal of lipid research 2008;49(3):654-62.
2008: Nalini Kaul; Renee Kreml; J Alejandro Austria; Melanie N Richard; Andrea L Edel; Elena Dibrov; Satoru Hirono; Marjorie E Zettler; Grant N Pierce
A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers.
Journal of the American College of Nutrition 2008;27(1):51-8.
2007: Vathsala E R Edirimanne; Connie W H Woo; Chris Siow; Grant N Pierce; Jiu Y Xie; Karmin O
Homocysteine stimulates NADPH oxidase-mediated superoxide production leading to endothelial dysfunction in rats.
Canadian journal of physiology and pharmacology 2007;85(12):1236-47.
2007: Chantal Bassett; Elena Dibrov; Annette L Kneesh; Paul K M Cheung; Kaitlin G Y Lee; Helen K Alexander; Behzad Yeganeh; Mohammed H Moghadasian; Grant N Pierce
Dietary flaxseed inhibits atherosclerosis in the LDL receptor-deficient mouse in part through antiproliferative and anti-inflammatory actions.
American journal of physiology. Heart and circulatory physiology 2007;293(4):H2394-402.
2007: Mohammad M Abdullah; Zuyuan Xu; Grant N Pierce; Mohammed H Moghadasian
The effects of simultaneous administration of dietary conjugated linoleic acid and telmisartan on cardiovascular risks in rats.
Lipids 2007;42(9):855-64.
2007: Melanie N Richard; Justin F Deniset; Annette L Kneesh; David Blackwood; Grant N Pierce
Mechanical stretching stimulates smooth muscle cell growth, nuclear protein import, and nuclear pore expression through mitogen-activated protein kinase activation.
The Journal of biological chemistry 2007;282(32):23081-8.
2007: Cecilia Hurtado; Jeffrey T Wigle; Elena Dibrov; Thane G Maddaford; Grant N Pierce
A comparison of adenovirally delivered molecular methods to inhibit Na+/Ca2+ exchange.
Journal of molecular and cellular cardiology 2007;43(1):49-53.
2007: A Al-Khalifa; Thane G Maddaford; M N Chahine; J Alejandro Austria; Andrea L Edel; Melanie N Richard; Bradley P Ander; N Gavel; M Kopilas; R Ganguly; P K Ganguly; Grant N Pierce
Effect of dietary hempseed intake on cardiac ischemia-reperfusion injury.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;292(3):R1198-203.
2007: Melanie N Richard; R Ganguly; S N Steigerwald; A Al-Khalifa; Grant N Pierce
Dietary hempseed reduces platelet aggregation.
Journal of thrombosis and haemostasis : JTH 2007;5(2):424-5.
2007: Randolph S Faustino; Lyle N W Stronger; Melanie N Richard; Michael P Czubryt; David A Ford; Michele A Prociuk; Elena Dibrov; Grant N Pierce
RanGAP-mediated nuclear protein import in vascular smooth muscle cells is augmented by lysophosphatidylcholine.
Molecular pharmacology 2007;71(2):438-45.
2007: Bradley P Ander; Cecilia Hurtado; Carla S Raposo; Thane G Maddaford; Justin F Deniset; Larry V Hryshko; Grant N Pierce; Anton Lukas
Differential sensitivities of the NCX1.1 and NCX1.3 isoforms of the Na+-Ca2+ exchanger to alpha-linolenic acid.
Cardiovascular research 2007;73(2):395-403.
2006: Chantal Bassett; A-M Weber; Bradley P Ander; Penelope P Rampersad; S Steigerwald; Jeffrey T Wigle; R W Mitchell; Edwin A Kroeger; James S C Gilchrist; M M Moghadasian; Anton Lukas; Grant N Pierce
Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits.
American journal of physiology. Heart and circulatory physiology 2006;291(6):H2987-96.
2006: Raúl A Dulce; Cecilia Hurtado; Irene L Ennis; Carolina D Garciarena; María C Alvarez; Claudia I Caldiz; Grant N Pierce; Enrique Portiansky; Gladys E Chiappe de Cingolani; María C Camilión de Hurtado
Endothelin-1 induced hypertrophic effect in neonatal rat cardiomyocytes: involvement of Na+/H+ and Na+/Ca2+ exchangers.
Journal of molecular and cellular cardiology 2006;41(5):807-15.
2006: Cecilia Hurtado; Michele A Prociuk; Thane G Maddaford; Elena Dibrov; Nasrin Mesaeli; Larry V Hryshko; Grant N Pierce
Cells expressing unique Na+/Ca2+ exchange (NCX1) splice variants exhibit different susceptibilities to Ca2+ overload.
American journal of physiology. Heart and circulatory physiology 2006;290(5):H2155-62.
2006: Randolph S Faustino; Delphine C Rousseau; Melanie N Landry; Annette L Kostenuk; Grant N Pierce
Effects of mitogen-activated protein kinases on nuclear protein import.
Canadian journal of physiology and pharmacology 2006;84(3-4):469-75.
2006: Andrea L Edel; Melanie Kopilas; Tod A Clark; Floribeth Aguilar; Pallub K Ganguly; Clayton E Heyliger; Grant N Pierce
Short-term bioaccumulation of vanadium when ingested with a tea decoction in streptozotocin-induced diabetic rats.
Metabolism: clinical and experimental 2006;55(2):263-70.
2005: Connie W H Woo; Chris Siow; Grant N Pierce; Patrick C Choy; Gerald Y Minuk; David Mymin; Karmin O
Hyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factors.
American journal of physiology. Endocrinology and metabolism 2005;288(5):E1002-10.
2005: Cecilia Hurtado; Bradley P Ander; Thane G Maddaford; Anton Lukas; Larry V Hryshko; Grant N Pierce
Adenovirally delivered shRNA strongly inhibits Na+-Ca2+ exchanger expression but does not prevent contraction of neonatal cardiomyocytes.
Journal of molecular and cellular cardiology 2005;38(4):647-54.
2004: Bradley P Ander; Anna R Weber; Penelope P Rampersad; James S C Gilchrist; Grant N Pierce; Anton Lukas
Dietary flaxseed protects against ventricular fibrillation induced by ischemia-reperfusion in normal and hypercholesterolemic Rabbits.
The Journal of nutrition 2004;134(12):3250-6.
2004: Tod A Clark; Andrea L Edel; Clayton E Heyliger; Grant N Pierce
Effective control of glycemic status and toxicity in Zucker diabetic fatty rats with an orally administered vanadate compound.
Canadian journal of physiology and pharmacology 2004;82(10):888-94.
2004: Tod A Clark; Clayton E Heyliger; Andrea L Edel; Danny P Goel; Grant N Pierce
Codelivery of a tea extract prevents morbidity and mortality associated with oral vanadate therapy in streptozotocin-induced diabetic rats.
Metabolism: clinical and experimental 2004;53(9):1145-51.
2004: Randolph S Faustino; Tod A Clark; S Sobrattee; M P Czubryl; Grant N Pierce
Differential antioxidant properties of red wine in water soluble and lipid soluble peroxyl radical generating systems.
Molecular and cellular biochemistry 2004;263(1-2):211-5.
2004: Danny P Goel; Jonathan D Geiger; Jacqueline J Shan; Dean Kriellaars; Grant N Pierce
Doping-control urinalysis of a ginseng extract, Cold-FX, in athletes.
International journal of sport nutrition and exercise metabolism 2004;14(4):473-80.
2004: Casie L Shields; Gordon G Giesbrecht; Grant N Pierce; A Elizabeth Ready
The effects of a moderate physical activity program on thermoregulatory responses in a warm environment in men.
Canadian journal of applied physiology = Revue canadienne de physiologie appliquée 2004;29(4):379-94.
2004: Marjorie E Zettler; Michele A Prociuk; J Alejandro Austria; Guangming Zhong; Grant N Pierce
Oxidized low-density lipoprotein retards the growth of proliferating cells by inhibiting nuclear translocation of cell cycle proteins.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(4):727-32.
2004: Paramjit S Tappia; Thane G Maddaford; Cecilia Hurtado; Elena Dibrov; J Alejandro Austria; Nidhi Sahi; Vincenzo Panagia; Grant N Pierce
Defective phosphatidic acid-phospholipase C signaling in diabetic cardiomyopathy.
Biochemical and biophysical research communications 2004;316(1):280-9.
2004: Grant N Pierce
Is infection a component of atherosclerosis?
Journal of muscle research and cell motility 2004;25(8):617-8.
2004: Pavel Dibrov; Elena Dibrov; Grant N Pierce; Michael Galperin
Salt in the wound: a possible role of Na+ gradient in chlamydial infection.
Journal of molecular microbiology and biotechnology 2004;8(1):1-6.
2003: Satoru Hirono; Elena Dibrov; Cecilia Hurtado; Annette Kostenuk; Robin Ducas; Grant N Pierce
Chlamydia pneumoniae stimulates proliferation of vascular smooth muscle cells through induction of endogenous heat shock protein 60.
Circulation research 2003;93(8):710-6.
2003: Danny P Goel; L David A Ford; Grant N Pierce
Lysophospholipids do not directly modulate Na(+)-H+ exchange.
Molecular and cellular biochemistry 2003;251(1-2):3-7.
2003: David Wilson; Hamid Massaeli; James C Russell; Grant N Pierce; Peter Zahradka
Low matrix metalloproteinase levels precede vascular lesion formation in the JCR:LA-cp rat.
Molecular and cellular biochemistry 2003;249(1-2):151-5.
2003: David Wilson; Hamid Massaeli; Grant N Pierce; Peter Zahradka
Native and minimally oxidized low density lipoprotein depress smooth muscle matrix metalloproteinase levels.
Molecular and cellular biochemistry 2003;249(1-2):141-9.
2003: Randolph S Faustino; S Sobrattee; Andrea L Edel; Grant N Pierce
Comparative analysis of the phenolic content of selected Chilean, Canadian and American Merlot red wines.
Molecular and cellular biochemistry 2003;249(1-2):11-9.
2003: Satoru Hirono; Grant N Pierce
Dissemination of Chlamydia pneumoniae to the vessel wall in atherosclerosis.
Molecular and cellular biochemistry 2003;246(1-2):91-5.
2003: Bernard Abrenica; Grant N Pierce; James S C Gilchrist
Nucleoplasmic calcium regulation in rabbit aortic vascular smooth muscle cells.
Canadian journal of physiology and pharmacology 2003;81(3):301-10.
2003: Marjorie E Zettler; Michele A Prociuk; J Alejandro Austria; Hamid Massaeli; Guangming Zhong; Grant N Pierce
OxLDL stimulates cell proliferation through a general induction of cell cycle proteins.
American journal of physiology. Heart and circulatory physiology 2003;284(2):H644-53.
2003: Paramjit S Tappia; Thane G Maddaford; Cecilia Hurtado; Vincenzo Panagia; Grant N Pierce
Depressed phosphatidic acid-induced contractile activity of failing cardiomyocytes.
Biochemical and biophysical research communications 2003;300(2):457-63.
2003: Bradley P Ander; Chantal Mc Dupasquier; Michele A Prociuk; Grant N Pierce
Polyunsaturated fatty acids and their effects on cardiovascular disease.
Experimental and clinical cardiology 2003;8(4):164-72.
2002: Danny P Goel; Thane G Maddaford; Grant N Pierce
Effects of omega-3 polyunsaturated fatty acids on cardiac sarcolemmal Na(+)/H(+) exchange.
American journal of physiology. Heart and circulatory physiology 2002;283(4):H1688-94.
2002: Niels G Giddins; Kim Duncan; Rabindranath Persad; James S C Gilchrist; Grant N Pierce
Effects of chronic, rapid right atrial pacing on cardiac hemodynamics and myofibrillar ATPase activity in piglets.
The Canadian journal of cardiology 2002;18(2):157-61.
2002: Randolph S Faustino; Michael P Czubryt; Grant N Pierce
Determining influence of oxidants on nuclear transport using digitonin-permeabilized cell assay.
Methods in enzymology 2002;352():123-34.
2002: James S C Gilchrist; Bernard Abrenica; Patrick J DiMario; Michael P Czubryt; Grant N Pierce
Nucleolin is a calcium-binding protein.
Journal of cellular biochemistry 2002;85(2):268-78.
2001: C Hurtado; Grant N Pierce
Sodium-hydrogen exchange inhibition: pre-versus post-ischemic treatment.
Basic research in cardiology 2001;96(4):312-7.
2001: T Misra; J C Russell; Tod A Clark; Grant N Pierce
Mg2+-dependent ATPase activity in cardiac myofibrils from the insulin-resistant JCR:LA-cp rat.
Advances in experimental medicine and biology 2001;498():247-52.
2001: Hamid Massaeli; Cecilia Hurtado; J Alejandro Austria; Grant N Pierce
Increase in nuclear calcium in smooth muscle cells exposed to oxidized low density lipoprotein.
Free radical research 2001;34(1):9-16.
2001: Marjorie E Zettler; Grant N Pierce
Growth-promoting effects of oxidized low density lipoprotein.
The Canadian journal of cardiology 2001;17(1):73-9.
2000: L Liu; H Hu; H Ji; Andrew D Murdin; Grant N Pierce; Guangming Zhong
Chlamydia pneumoniae infection significantly exacerbates aortic atherosclerosis in an LDLR-/- mouse model within six months.
Molecular and cellular biochemistry 2000;215(1-2):123-8.
2000: C Hurtado; Grant N Pierce
Inhibition of Na(+)/H(+) exchange at the beginning of reperfusion is cardioprotective in isolated, beating adult cardiomyocytes.
Journal of molecular and cellular cardiology 2000;32(10):1897-907.
2000: R Jankowski; Michael P Czubryt; Grant N Pierce
The nuclear protein import assay in vascular smooth muscle cells.
Journal of pharmacological and toxicological methods 2000;44(2):421-7.
2000: Danny P Goel; Alba Vecchini; Vincenzo Panagia; Grant N Pierce
Altered cardiac Na(+)/H(+) exchange in phospholipase D-treated sarcolemmal vesicles.
American journal of physiology. Heart and circulatory physiology 2000;279(3):H1179-84.
2000: Hamid Massaeli; J Alejandro Austria; Grant N Pierce
Overexpression of SERCA2 Atpase in vascular smooth muscle cells treated with oxidized low density lipoprotein.
Molecular and cellular biochemistry 2000;207(1-2):137-41.
2000: Marjorie E Zettler; Grant N Pierce
Cell cycle proteins and atherosclerosis.
Herz 2000;25(2):100-7.
2000: Hamid Massaeli; J Alejandro Austria; Grant N Pierce
Lesions in ryanodine channels in smooth muscle cells exposed to oxidized low density lipoprotein.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):328-34.
2000: Michael P Czubryt; J Alejandro Austria; Grant N Pierce
Hydrogen peroxide inhibition of nuclear protein import is mediated by the mitogen-activated protein kinase, ERK2.
The Journal of cell biology 2000;148(1):7-16.
2000: Tod A Clark; Grant N Pierce
Cardiovascular complications of non-insulin-dependent diabetes: the JCR:LA-cp rat.
Journal of pharmacological and toxicological methods 2000;43(1):1-10.
1999: Hamid Massaeli; Cecilia Hurtado; J Alejandro Austria; Grant N Pierce
Oxidized low-density lipoprotein induces cytoskeletal disorganization in smooth muscle cells.
The American journal of physiology 1999;277(5 Pt 2):H2017-25.
1999: Hamid Massaeli; J Alejandro Austria; Grant N Pierce
Chronic exposure of smooth muscle cells to minimally oxidized LDL results in depressed inositol 1,4,5-trisphosphate receptor density and Ca(2+) transients.
Circulation research 1999;85(6):515-23.
1999: Thane G Maddaford; Cecilia Hurtado; S Sobrattee; Michael P Czubryt; Grant N Pierce
A model of low-flow ischemia and reperfusion in single, beating adult cardiomyocytes.
The American journal of physiology 1999;277(2 Pt 2):H788-98.
1999: Danny P Goel; Grant N Pierce
Role of the sodium-hydrogen exchanger in ischemia-reperfusion injury in diabetes.
Journal of thrombosis and thrombolysis 1999;8(1):45-52.
1999: Hamid Massaeli; S Sobrattee; Grant N Pierce
The importance of lipid solubility in antioxidants and free radical generating systems for determining lipoprotein proxidation.
Free radical biology & medicine 1999;26(11-12):1524-30.
1999: T Misra; James S C Gilchrist; J C Russell; Grant N Pierce
Cardiac myofibrillar and sarcoplasmic reticulum function are not depressed in insulin-resistant JCR:LA-cp rats.
The American journal of physiology 1999;276(6 Pt 2):H1811-7.
1999: H Hu; Grant N Pierce; Guangming Zhong
The atherogenic effects of chlamydia are dependent on serum cholesterol and specific to Chlamydia pneumoniae.
The Journal of clinical investigation 1999;103(5):747-53.
1998: Raymond R Padua; P L Merle; Bradley Doble; CH Yu; Peter Zahradka; Grant N Pierce; Vincenzo Panagia; Elissavet Kardami
FGF-2-induced negative inotropism and cardioprotection are inhibited by chelerythrine: involvement of sarcolemmal calcium-independent protein kinase C.
Journal of molecular and cellular cardiology 1998;30(12):2695-709.
1998: S O Wali; Ahmed BaHammam; Hamid Massaeli; Grant N Pierce; N Iliskovic; Pawan K Singal; Meir H Kryger
Susceptibility of LDL to oxidative stress in obstructive sleep apnea.
Sleep 1998;21(3):290-6.
1998: S Eng; Thane G Maddaford; Elissavet Kardami; Grant N Pierce
Protection against myocardial ischemic/reperfusion injury by inhibitors of two separate pathways of Na+ entry.
Journal of molecular and cellular cardiology 1998;30(4):829-35.
1998: JT Wong; K Tran; Grant N Pierce; A C Chan; Karmin O; Patrick C Choy
Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells.
The Journal of biological chemistry 1998;273(12):6830-6.
1997: Michael P Czubryt; J C Russell; John Sarantopoulos; James S C Gilchrist; Grant N Pierce
Age- and sex-related differences in nuclear lipid content and nucleoside triphosphatase activity in the JCR:LA-cp corpulent rat.
Molecular and cellular biochemistry 1997;176(1-2):327-35.
1997: Thane G Maddaford; Grant N Pierce
Myocardial dysfunction is associated with activation of Na+/H+ exchange immediately during reperfusion.
The American journal of physiology 1997;273(5 Pt 2):H2232-9.
1997: Thane G Maddaford; J C Russell; Grant N Pierce
Postischemic cardiac performance in the insulin-resistant JCR:LA-cp rat.
The American journal of physiology 1997;273(3 Pt 2):H1187-92.
1997: Michael P Czubryt; B Ramjiawan; Grant N Pierce
The nuclear membrane integrity assay.
Molecular and cellular biochemistry 1997;172(1-2):97-102.
1997: Grant N Pierce; J C Russell
Regulation of intracellular Ca2+ in the heart during diabetes.
Cardiovascular research 1997;34(1):41-7.
1997: Grant N Pierce; Thane G Maddaford; J C Russell
Cardiovascular dysfunction in insulin-dependent and non-insulin-dependent animal models of diabetes mellitus.
Canadian journal of physiology and pharmacology 1997;75(4):343-50.
1997: B Ramjiawan; Michael P Czubryt; Hamid Massaeli; James S C Gilchrist; Grant N Pierce
Oxidation of nuclear membrane cholesterol inhibits nucleoside triphosphatase activity.
Free radical biology & medicine 1997;23(4):556-62.
1996: B Ramjiawan; Michael P Czubryt; James S C Gilchrist; Grant N Pierce
Nuclear membrane cholesterol can modulate nuclear nucleoside triphosphatase activity.
Journal of cellular biochemistry 1996;63(4):442-52.
1996: Michael P Czubryt; J C Russell; John Sarantopoulos; Grant N Pierce
Nuclear cholesterol content and nucleoside triphosphatase activity are altered in the JCR:LA-cp corpulent rat.
Journal of cellular biochemistry 1996;63(3):349-57.
1996: Michael P Czubryt; B Ramjiawan; James S C Gilchrist; Hamid Massaeli; Grant N Pierce
The presence and partitioning of calcium binding proteins in hepatic and cardiac nuclei.
Journal of molecular and cellular cardiology 1996;28(3):455-65.
1996: Michael P Czubryt; Vincenzo Panagia; Grant N Pierce
The roles of free radicals, peroxides and oxidized lipoproteins in second messenger system dysfunction.
EXS 1996;76():57-69.
1995: L Liu; K B Pasumarthi; R R Padua; Hamid Massaeli; Robert R Fandrich; Grant N Pierce; Peter A Cattini; Elissavet Kardami
Adult cardiomyocytes express functional high-affinity receptors for basic fibroblast growth factor.
The American journal of physiology 1995;268(5 Pt 2):H1927-38.
1995: Hamid Massaeli; Grant N Pierce
Involvement of lipoproteins, free radicals, and calcium in cardiovascular disease processes.
Cardiovascular research 1995;29(5):597-603.
1995: JC Docherty; Thane G Maddaford; D F Dubo; N L Choptain; Grant N Pierce
Na(+)-Ca2+ exchange and Ca2+ channel characteristics in bovine aorta and coronary artery smooth muscle sarcolemmal membranes.
Molecular and cellular biochemistry 1995;144(1):61-6.
1995: Jason R B Dyck; Thane G Maddaford; Grant N Pierce; Larry Fliegel
Induction of expression of the sodium-hydrogen exchanger in rat myocardium.
Cardiovascular research 1995;29(2):203-8.
1995: Grant N Pierce; Michael P Czubryt
The contribution of ionic imbalance to ischemia/reperfusion-induced injury.
Journal of molecular and cellular cardiology 1995;27(1):53-63.
1994: B B Lonsberry; D F Dubo; S M Thomas; JC Docherty; Thane G Maddaford; Grant N Pierce
Effect of high-dose verapamil administration on the Ca2+ channel density in rat cardiac tissue.
Pharmacology 1994;49(1):23-32.
1994: James S C Gilchrist; Michael P Czubryt; Grant N Pierce
Calcium and calcium-binding proteins in the nucleus.
Molecular and cellular biochemistry 1994;135(1):79-88.
1993: C D McPherson; Grant N Pierce; William C Cole
Ischemic cardioprotection by ATP-sensitive K+ channels involves high-energy phosphate preservation.
The American journal of physiology 1993;265(5 Pt 2):H1809-18.
1993: Grant N Pierce; William C Cole; K Liu; Hamid Massaeli; Thane G Maddaford; Y J Chen; C D McPherson; S Jain; D Sontag
Modulation of cardiac performance by amiloride and several selected derivatives of amiloride.
The Journal of pharmacology and experimental therapeutics 1993;265(3):1280-91.
1993: H P Meng; Thane G Maddaford; Grant N Pierce
Effect of amiloride and selected analogues on postischemic recovery of cardiac contractile function.
The American journal of physiology 1993;264(6 Pt 2):H1831-5.
1993: James S C Gilchrist; Grant N Pierce
Identification and purification of a calcium-binding protein in hepatic nuclear membranes.
The Journal of biological chemistry 1993;268(6):4291-9.
1993: K Liu; Hamid Massaeli; Grant N Pierce
The action of oxidized low density lipoprotein on calcium transients in isolated rabbit cardiomyocytes.
The Journal of biological chemistry 1993;268(6):4145-51.
1993: K Liu; Grant N Pierce
The effects of low density lipoprotein on calcium transients in isolated rabbit cardiomyocytes.
The Journal of biological chemistry 1993;268(5):3767-75.
1992: B B Lonsberry; Michael P Czubryt; D F Dubo; James S C Gilchrist; JC Docherty; Thane G Maddaford; Grant N Pierce
Effect of chronic administration of verapamil on Ca++ channel density in rat tissue.
The Journal of pharmacology and experimental therapeutics 1992;263(2):540-5.
1992: K Z Liu; T E Cuddy; Grant N Pierce
Oxidative status of lipoproteins in coronary disease patients.
American heart journal 1992;123(2):285-90.
1991: K Z Liu; B Ramjiawan; M J Kutryk; Grant N Pierce
Effects of oxidative modification of cholesterol in isolated low density lipoproteins on cultured smooth muscle cells.
Molecular and cellular biochemistry 1991;108(1):49-56.
1991: K Z Liu; Thane G Maddaford; B Ramjiawan; M J Kutryk; Grant N Pierce
Effects of cholesterol oxidase on cultured vascular smooth muscle cells.
Molecular and cellular biochemistry 1991;108(1):39-48.
1991: H P Meng; B B Lonsberry; Grant N Pierce
Influence of perfusate pH on the postischemic recovery of cardiac contractile function: involvement of sodium-hydrogen exchange.
The Journal of pharmacology and experimental therapeutics 1991;258(3):772-7.
1991: H Meng; Grant N Pierce
Involvement of sodium in the protective effect of 5-(N,N-dimethyl)-amiloride on ischemia-reperfusion injury in isolated rat ventricular wall.
The Journal of pharmacology and experimental therapeutics 1991;256(3):1094-100.
1991: M J Kutryk; Thane G Maddaford; B Ramjiawan; Grant N Pierce
Oxidation of membrane cholesterol alters active and passive transsarcolemmal calcium movement.
Circulation research 1991;68(1):18-26.
1990: H Meng; Grant N Pierce
Metabolic and physiological response of the rabbit to continuous and intermittent treadmill exercise.
Canadian journal of physiology and pharmacology 1990;68(7):856-62.
1990: H P Meng; Grant N Pierce
Protective effects of 5-(N,N-dimethyl)amiloride on ischemia-reperfusion injury in hearts.
The American journal of physiology 1990;258(5 Pt 2):H1615-9.
1990: H P Meng; M J Kutryk; Grant N Pierce
Effect of platelet-activating factor (PAF) on sodium calcium exchange in cardiac sarcolemmal vesicles.
Molecular and cellular biochemistry 1990;92(1):45-51.
1990: Grant N Pierce; Thane G Maddaford; E A Kroeger; E J Cragoe
Protection by benzamil against dysfunction and damage in rat myocardium after calcium depletion and repletion.
The American journal of physiology 1990;258(1 Pt 2):H17-23.
1990: Grant N Pierce; B Ramjiawan; Naranjan S Dhalla; R Ferrari
Na(+)-H+ exchange in cardiac sarcolemmal vesicles isolated from diabetic rats.
The American journal of physiology 1990;258(1 Pt 2):H255-61.
1989: Grant N Pierce; Vincenzo Panagia
Role of phosphatidylinositol in cardiac sarcolemmal membrane sodium-calcium exchange.
The Journal of biological chemistry 1989;264(26):15344-50.
1989: Grant N Pierce; G A Langer; G B Wright; M J Kutryk
Calcium is rapidly exchangeable in cultured vascular smooth muscle cells from rabbit aorta.
Journal of molecular and cellular cardiology 1989;21(9):889-99.
1989: Grant N Pierce; N Afzal; E A Kroeger; M K Lockwood; M J Kutryk; Curtis D Eckhert; Naranjan S Dhalla
Cataract formation is prevented by administration of verapamil to diabetic rats.
Endocrinology 1989;125(2):730-5.
1989: Grant N Pierce; P S Sekhon; H P Meng; Thane G Maddaford
Effects of chronic swimming training on cardiac sarcolemmal function and composition.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;66(4):1715-21.
1989: N Afzal; Grant N Pierce; V Elimban; RE Beamish; Naranjan S Dhalla
Influence of verapamil on some subcellular defects in diabetic cardiomyopathy.
The American journal of physiology 1989;256(4 Pt 1):E453-8.
1989: Grant N Pierce; M K Lockwood; Curtis D Eckhert
Cardiac contracile protein ATPase activity in a diet induced model of noninsulin dependent diabetes mellitus.
The Canadian journal of cardiology 1989;5(2):117-20.
1988: M J Kutryk; Grant N Pierce
Stimulation of sodium-calcium exchange by cholesterol incorporation into isolated cardiac sarcolemmal vesicles.
The Journal of biological chemistry 1988;263(26):13167-72.
1988: N Afzal; Pallab K Ganguly; KS Dhalla; Grant N Pierce; Pawan K Singal; Naranjan S Dhalla
Beneficial effects of verapamil in diabetic cardiomyopathy.
Diabetes 1988;37(7):936-42.
1987: Grant N Pierce
Cationic interactions with Na+-H+ exchange and passive Na+ flux in cardiac sarcolemmal vesicles.
Molecular and cellular biochemistry 1987;78(1):89-94.
1987: M J Kutryk; Grant N Pierce; Naranjan S Dhalla
Alterations in heart and serum lysosomal activities in streptozotocin-induced diabetes.
Basic research in cardiology 1987;82(3):271-8.
1985: Naranjan S Dhalla; Grant N Pierce; I R Innes; RE Beamish
Pathogenesis of cardiac dysfunction in diabetes mellitus.
The Canadian journal of cardiology 1985;1(4):263-81.
1985: V Panagia; Grant N Pierce; KS Dhalla; Pallab K Ganguly; RE Beamish; Naranjan S Dhalla
Adaptive changes in subcellular calcium transport during catecholamine-induced cardiomyopathy.
Journal of molecular and cellular cardiology 1985;17(4):411-20.
1984: Naranjan S Dhalla; L E Alto; C E Heyliger; Grant N Pierce; V Panagia; P K Singal
Sarcoplasmic reticular Ca2+-pump adaptation in cardiac hypertrophy due to pressure overload in pigs.
European heart journal 1984;5 Suppl F():323-8.
1984: Grant N Pierce; M J Kutryk; KS Dhalla; RE Beamish; Naranjan S Dhalla
Biochemical alterations in heart after exhaustive swimming in rats.
Journal of applied physiology: respiratory, environmental and exercise physiology 1984;57(2):326-31.
1983: Grant N Pierce; M J Kutryk; Naranjan S Dhalla
Alterations in Ca2+ binding by and composition of the cardiac sarcolemmal membrane in chronic diabetes.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(17):5412-6.
1983: Pallab K Ganguly; Grant N Pierce; KS Dhalla; Naranjan S Dhalla
Defective sarcoplasmic reticular calcium transport in diabetic cardiomyopathy.
The American journal of physiology 1983;244(6):E528-35.
1982: C E Heyliger; Grant N Pierce; P K Singal; RE Beamish; Naranjan S Dhalla
Cardiac alpha- and beta-adrenergic receptor alterations in diabetic cardiomyopathy.
Basic research in cardiology 1982;77(6):610-8.
1980: Naranjan S Dhalla; L E Alto; Grant N Pierce; M J Daly; K S Dhillon; R Compier; A Guerin
Cardiac effects of beta-adrenergic receptor antagonists: beta-moderators versus beta-blockers.
Clinical therapeutics 1980;3(4):254-9.