Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Alain Pierré

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Mice

Anatomy

Procedures

Concepts & Ideas

Structure-Activity Relationship

Disorders

Physiology

Genes & Molecular Sequences

Molecular Structure

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Tao Yungan; Leteur Céline; Yang Ceyao; Zhang Ping; Castedo Maria; Pierré Alain; Golsteyn Roy M; Bourhis Jean; Kroemer Guido; Deutsch Eric
Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.
Do Quyên; Tian Wen; Yougnia Rodrigue; Gaslonde Thomas; Pfeiffer Bruno; Pierré Alain; Léonce Stéphane; Kraus-Berthier Laurence; David-Cordonnier Marie-Hélène; Depauw Sabine; Lansiaux Amélie; Mazinghien Romain; Koch Michel; Tillequin François; Michel Sylvie; Dufat Hanh
Synthesis, cytotoxic activity, and DNA binding properties of antitumor cis-1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine cinnamoyl esters.
Gallet Sebastien; Flouquet Nathalie; Carato Pascal; Pfeiffer Bruno; Renard Pierre; Léonce Stéphane; Pierré Alain; Berthelot Pascal; Lebegue Nicolas
Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Alain Pierré (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Tao Yungan; Leteur Céline; Yang Ceyao; Zhang Ping; Castedo Maria; Pierré Alain; Golsteyn Roy M; Bourhis Jean; Kroemer Guido; Deutsch Eric
Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.
Cell cycle (Georgetown, Tex.) 2009;8(8):1196-205.
2009: Do Quyên; Tian Wen; Yougnia Rodrigue; Gaslonde Thomas; Pfeiffer Bruno; Pierré Alain; Léonce Stéphane; Kraus-Berthier Laurence; David-Cordonnier Marie-Hélène; Depauw Sabine; Lansiaux Amélie; Mazinghien Romain; Koch Michel; Tillequin François; Michel Sylvie; Dufat Hanh
Synthesis, cytotoxic activity, and DNA binding properties of antitumor cis-1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine cinnamoyl esters.
Bioorganic & medicinal chemistry 2009;17(5):1918-27.
2009: Gallet Sebastien; Flouquet Nathalie; Carato Pascal; Pfeiffer Bruno; Renard Pierre; Léonce Stéphane; Pierré Alain; Berthelot Pascal; Lebegue Nicolas
Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.
Bioorganic & medicinal chemistry 2009;17(3):1132-8.
2009: Parmentier Jean-Gilles; Portevin Bernard; Golsteyn Roy M; Pierré Alain; Hickman John; Gloanec Philippe; De Nanteuil Guillaume
Synthesis and CHK1 inhibitory potency of Hymenialdisine analogues.
Bioorganic & medicinal chemistry letters 2009;19(3):841-4.
2008: Marminon Christelle; Anizon Fabrice; Moreau Pascale; Pfeiffer Bruno; Pierré Alain; Golsteyn Roy M; Peixoto Paul; Hildebrand Marie-Paule; David-Cordonnier Marie-Hélène; Lozach Olivier; Meijer Laurent; Prudhomme Michelle
Rebeccamycin derivatives as dual DNA-damaging agents and potent checkpoint kinase 1 inhibitors.
Molecular pharmacology 2008;74(6):1620-9.
2008: Do Quyên; Thi Mai Huong Doan; Gaslonde Thomas; Pfeiffer Bruno; Léonce Stéphane; Pierré Alain; Michel Sylvie; Tillequin François; Dufat Hanh
Structure-activity relationships in the acronycine and benzo[b]acronycine series: role of the pyran ring.
European journal of medicinal chemistry 2008;43(12):2677-87.
2008: Boutefnouchet Sabrina; Gaboriaud-Kolar Nicolas; Nguyen Tuan Minh; Depauw Sabine; David-Cordonnier Marie-Hélène; Pfeiffer Bruno; Léonce Stéphane; Pierré Alain; Tillequin François; Lallemand Marie-Christine; Michel Sylvie
Synthesis, cytotoxic activity, and mechanism of action of furo[2,3-c]acridin-6-one and benzo[b]furo[3,2-h]acridin-6-one analogues of psorospermin and acronycine.
Journal of medicinal chemistry 2008;51(22):7287-97.
2008: Lefoix Myriam; Coudert Gérard; Routier Sylvain; Pfeiffer Bruno; Caignard Daniel-Henri; Hickman John; Pierré Alain; Golsteyn Roy M; Léonce Stéphane; Bossard Céline; Mérour Jean-Yves
Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors.
Bioorganic & medicinal chemistry 2008;16(9):5303-21.
2007: Takagi Kazutaka; Dexheimer Thomas S; Redon Christophe; Sordet Olivier; Agama Keli; Lavielle Gilbert; Pierré Alain; Bates Susan E; Pommier Yves
Novel E-ring camptothecin keto analogues (S38809 and S39625) are stable, potent, and selective topoisomerase I inhibitors without being substrates of drug efflux transporters.
Molecular cancer therapeutics 2007;6(12 Pt 1):3229-38.
2007: Hugon Bernadette; Anizon Fabrice; Bailly Christian; Golsteyn Roy M; Pierré Alain; Léonce Stéphane; Hickman John; Pfeiffer Bruno; Prudhomme Michelle
Synthesis and biological activities of isogranulatimide analogues.
Bioorganic & medicinal chemistry 2007;15(17):5965-80.
2007: Lansiaux Amélie; Léonce Stéphane; Kraus-Berthier Laurence; Bal-Mahieu Christine; Mazinghien Romain; Didier Sébastien; David-Cordonnier Marie-Hélène; Hautefaye Patrick; Lavielle Gilbert; Bailly Christian; Hickman John A; Pierré Alain
Novel stable camptothecin derivatives replacing the E-ring lactone by a ketone function are potent inhibitors of topoisomerase I and promising antitumor drugs.
Molecular pharmacology 2007;72(2):311-9.
2007: Gaslonde Thomas; Michel Sylvie; Koch Michel; Pfeiffer Bruno; Léonce Stéphane; Pierré Alain; Tillequin François
Synthesis and cytotoxic activity of dimeric analogs of acronycine in the benzo[b]pyrano[3,2-h]acridin-7-one series.
Chemical & pharmaceutical bulletin 2007;55(5):734-8.
2006: Sittisombut Chavalit; Boutefnouchet Sabrina; Trinh Van-Dufat Hanh; Tian Wen; Michel Sylvie; Koch Michel; Tillequin François; Pfeiffer Bruno; Pierré Alain
Synthesis and cytotoxic activity of benzo[a]pyrano[3,2-h] and [2,3-i]xanthone analogues of psorospermine, acronycine, and benzo[a]acronycine.
Chemical & pharmaceutical bulletin 2006;54(8):1113-8.
2006: Léonce Stéphane; Kraus-Berthier Laurence; Golsteyn Roy M; David-Cordonnier Marie-Hélène; Tardy Christelle; Lansiaux Amélie; Poindessous Virginie; Larsen Annette K; Pierré Alain
Generation of replication-dependent double-strand breaks by the novel N2-G-alkylator S23906-1.
Cancer research 2006;66(14):7203-10.
2006: Nguyen Tuan Minh; Sittisombut Chavalit; Boutefnouchet Sabrina; Lallemand Marie-Christine; Michel Sylvie; Koch Michel; Tillequin François; Mazinghien Romain; Lansiaux Amélie; David-Cordonnier Marie-Hélène; Pfeiffer Bruno; Kraus-Berthier Laurence; Léonce Stéphane; Pierré Alain
Synthesis, antitumor activity, and mechanism of action of benzo[a]pyrano[3,2-h]acridin-7-one analogues of acronycine.
Journal of medicinal chemistry 2006;49(11):3383-94.
2006: Guillaumel Jean; Léonce Stéphane; Pierré Alain; Renard Pierre; Pfeiffer Bruno; Arimondo Paola B; Monneret Claude
Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds.
European journal of medicinal chemistry 2006;41(3):379-86.
2005: Bongui Jean-Bernard; Elomri Abdelhakim; Cahard Dominique; Tillequin François; Pfeiffer Bruno; Pierré Alain; Seguin Elisabeth
Synthesis and cytotoxic activity of acronycine analogues in the benzo[c]pyrano[3,2-h]acridin-7-one and naphtho[1,2-b][1,7] and [1,10]-phenanthrolin-7(14H)-one series.
Chemical & pharmaceutical bulletin 2005;53(12):1540-6.
2005: Lebegue Nicolas; Gallet Sebastien; Flouquet Nathalie; Carato Pascal; Pfeiffer Bruno; Renard Pierre; Léonce Stéphane; Pierré Alain; Chavatte Philippe; Berthelot Pascal
Novel benzopyridothiadiazepines as potential active antitumor agents.
Journal of medicinal chemistry 2005;48(23):7363-73.
2005: Messaoudi Samir; Anizon Fabrice; Léonce Stéphane; Pierré Alain; Pfeiffer Bruno; Prudhomme Michelle
Synthesis and cytotoxicities of 7-aza rebeccamycin analogues bearing various substituents on the sugar moiety, on the imide nitrogen and on the carbazole framework.
European journal of medicinal chemistry 2005;40(10):961-71.
2005: Doan Thi Mai Huong; Gaslonde Thomas; Michel Sylvie; Koch Michel; Tillequin François; Bailly Christian; David-Cordonnier Marie-Hélène; Pfeiffer Bruno; Léonce Stéphane; Pierré Alain
Design, synthesis, and cytotoxic activity of Michael acceptors and enol esters in the benzo[b]acronycine series.
Chemical & pharmaceutical bulletin 2005;53(8):919-22.
2005: Duca Maria; Arimondo Paola B; Léonce Stéphane; Pierré Alain; Pfeiffer Bruno; Monneret Claude; Dauzonne Daniel
Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation.
Organic & biomolecular chemistry 2005;3(6):1074-80.
2005: Routier Sylvain; Peixoto Paul; Mérour Jean-Yves; Coudert Gérard; Dias Nathalie; Bailly Christian; Pierré Alain; Léonce Stéphane; Caignard Daniel-Henry
Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents.
Journal of medicinal chemistry 2005;48(5):1401-13.
2005: Duca Maria; Guianvarc'h Dominique; Meresse Philippe; Bertounesque Emmanuel; Dauzonne Daniel; Kraus-Berthier Laurence; Thirot Sylvie; Léonce Stéphane; Pierré Alain; Pfeiffer Bruno; Renard Pierre; Arimondo Paola B; Monneret Claude
Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.
Journal of medicinal chemistry 2005;48(2):593-603.
2005: David-Cordonnier Marie-Hélène; Laine William; Lansiaux Amélie; Rosu Frédéric; Colson Pierre; de Pauw Edwin; Michel Sylvie; Tillequin Francois; Koch Michel; Hickman John A; Pierré Alain; Bailly Christian
Covalent binding of antitumor benzoacronycines to double-stranded DNA induces helix opening and the formation of single-stranded DNA: unique consequences of a novel DNA-bonding mechanism.
Molecular cancer therapeutics 2005;4(1):71-80.
2005: Guillonneau Claude; Nault Annette; Raimbaud Eric; Léonce Stéphane; Kraus-Berthier Laurence; Pierré Alain; Goldstein Solo
Cytotoxic and antitumoral properties in a series of new, ring D modified, olivacine analogues.
Bioorganic & medicinal chemistry 2005;13(1):175-84.
2004: Bal Christine; Baldeyrou Brigitte; Moz Florence; Lansiaux Amélie; Colson Pierre; Kraus-Berthier Laurence; Léonce Stéphane; Pierré Alain; Boussard Marie-Françoise; Rousseau Anne; Wierzbicki Michel; Bailly Christian
Novel antitumor indenoindole derivatives targeting DNA and topoisomerase II.
Biochemical pharmacology 2004;68(10):1911-22.
2004: Prado Soizic; Michel Sylvie; Tillequin François; Koch Michel; Pfeiffer Bruno; Pierré Alain; Léonce Stéphane; Colson Pierre; Baldeyrou Brigitte; Lansiaux Amélie; Bailly Christian
Synthesis and cytotoxic activity of benzo[c][1,7] and [1,8]phenanthrolines analogues of nitidine and fagaronine.
Bioorganic & medicinal chemistry 2004;12(14):3943-53.
2004: Tran-Thi Hong Anh; Nguyen-Thi Thuan; Michel Sylvie; Tillequin Francois; Koch Michel; Pfeiffer Bruno; Pierré Alain; Trinh-Van-Dufat Hanh
Synthesis and cytotoxic activity of pyranocarbazole analogues of ellipticine and acronycine.
Chemical & pharmaceutical bulletin 2004;52(5):540-5.
2004: Guianvarc'h Dominique; Duca Maria; Boukarim Chawki; Kraus-Berthier Laurence; Léonce Stéphane; Pierré Alain; Pfeiffer Bruno; Renard Pierre; Arimondo Paola B; Monneret Claude; Dauzonne Daniel
Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin.
Journal of medicinal chemistry 2004;47(9):2365-74.
2004: Voldoire Aline; Moreau Pascale; Sancelme Martine; Matulova Maria; Léonce Stéphane; Pierré Alain; Hickman John; Pfeiffer Bruno; Renard Pierre; Dias Nathalie; Bailly Christian; Prudhomme Michelle
Analogues of antifungal tjipanazoles from rebeccamycin.
Bioorganic & medicinal chemistry 2004;12(8):1955-62.
2004: David-Cordonnier Marie-Hélène; Laine William; Gaslonde Thomas; Michel Sylvie; Tillequin Francois; Koch Michel; Léonce Stéphane; Pierré Alain; Bailly Christian
Design of novel antitumor DNA alkylating agents: the benzacronycine series.
Current medicinal chemistry. Anti-cancer agents 2004;4(2):83-92.
2004: Lisowski Vincent; Léonce Stéphane; Kraus-Berthier Laurence; Sopková-de Oliveira Santos Jana; Pierré Alain; Atassi Ghanem; Caignard Daniel-Henri; Renard Pierre; Rault Sylvain
Design, synthesis, and evaluation of novel thienopyrrolizinones as antitubulin agents.
Journal of medicinal chemistry 2004;47(6):1448-64.
2004: Doan Thi Mai Huong; Gaslonde Thomas; Michel Sylvie; Koch Michel; Tillequin François; Pfeiffer Bruno; Renard Pierre; Kraus-Berthier Laurence; Léonce Stéphane; Pierré Alain
Synthesis and cytotoxic and antitumor activity of 1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine diacid hemiesters and carbamates.
Chemical & pharmaceutical bulletin 2004;52(3):293-7.
2004: Blanchard Stéphanie; Rodriguez Ivan; Tardy Christelle; Baldeyrou Brigitte; Bailly Christian; Colson Pierre; Houssier Claude; Léonce Stéphane; Kraus-Berthier Laurence; Pfeiffer Bruno; Renard Pierre; Pierré Alain; Caubère Paul; Guillaumet Gérald
Synthesis of mono- and bisdihydrodipyridopyrazines and assessment of their DNA binding and cytotoxic properties.
Journal of medicinal chemistry 2004;47(4):978-87.
2004: Le Diguarher Thierry; Ortuno Jean-Claude; Shanks David; Guilbaud Nicolas; Pierré Alain; Raimbaud Eric; Fauchère Jean-Luc; Hickman John A; Tucker Gordon C; Casara Patrick J
Synthesis of N,N'-disubstituted 3-aminobenzo[c] and [d]azepin-2-ones as potent and specific farnesyl transferase inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(3):767-71.
2004: David-Cordonnier Marie Hélène; Laine William; Kouach Mostafa; Briand Gilbert; Vezin Hervé; Gaslonde Thomas; Michel Sylvie; Doan Thi Mai Huong; Tillequin Francois; Koch Michel; Léonce Stéphane; Pierré Alain; Bailly Christian
A transesterification reaction is implicated in the covalent binding of benzo[b]acronycine anticancer agents with DNA and glutathion.
Bioorganic & medicinal chemistry 2004;12(1):23-9.
2003: Moreau Pascale; Gaillard Nathalie; Marminon Christelle; Anizon Fabrice; Dias Nathalie; Baldeyrou Brigitte; Bailly Christian; Pierré Alain; Hickman John; Pfeiffer Bruno; Renard Pierre; Prudhomme Michelle
Semi-synthesis, topoisomerase I and kinases inhibitory properties, and antiproliferative activities of new rebeccamycin derivatives.
Bioorganic & medicinal chemistry 2003;11(23):4871-9.
2003: Le Diguarher Thierry; Chollet Anne-Marie; Bertrand Marc; Hennig Philippe; Raimbaud Eric; Sabatini Massimo; Guilbaud Nicolas; Pierré Alain; Tucker Gordon C; Casara Patrick
Stereospecific synthesis of 5-substituted 2-bisarylthiocyclopentane carboxylic acids as specific matrix metalloproteinase inhibitors.
Journal of medicinal chemistry 2003;46(18):3840-52.
2003: Hautefaye Patrick; Cimetière Bernard; Pierré Alain; Léonce Stéphane; Hickman John; Laine William; Bailly Christian; Lavielle Gilbert
Synthesis and pharmacological evaluation of novel non-lactone analogues of camptothecin.
Bioorganic & medicinal chemistry letters 2003;13(16):2731-5.
2003: Thi Mai Huong Doan; Gaslonde Thomas; Michel Sylvie; Tillequin François; Koch Michel; Bongui Jean-Bernard; Elomri Abdelhakim; Seguin Elisabeth; Pfeiffer Bruno; Renard Pierre; David-Cordonnier Marie-Hélène; Laine William; Bailly Christian; Kraus-Berthier Laurence; Léonce Stéphane; Hickman John A; Pierré Alain
Structure-activity relationships and mechanism of action of antitumor benzo[b]pyrano[3,2-h]acridin-7-one acronycine analogues.
Journal of medicinal chemistry 2003;46(14):3072-82.
2003: Le Diguarher Thierry; Ortuno Jean Claude; Dorey Gilbert; Shanks David; Guilbaud Nicolas; Pierré Alain; Fauchère Jean Luc; Hickman John A; Tucker Gordon C; Casara Patrick J
Parallel liquid synthesis of N,N'-Disubstituted 3-amino azepin-2-ones as potent and specific farnesyl transferase inhibitors.
Bioorganic & medicinal chemistry 2003;11(14):3193-204.
2003: Marminon Christelle; Pierré Alain; Pfeiffer Bruno; Pérez Valérie; Léonce Stéphane; Renard Pierre; Prudhomme Michelle
Syntheses and antiproliferative activities of rebeccamycin analogues bearing two 7-azaindole moieties.
Bioorganic & medicinal chemistry 2003;11(5):679-87.
2003: Marminon Christelle; Pierré Alain; Pfeiffer Bruno; Pérez Valérie; Léonce Stéphane; Joubert Alexandra; Bailly Christian; Renard Pierre; Hickman John; Prudhomme Michelle
Syntheses and antiproliferative activities of 7-azarebeccamycin analogues bearing one 7-azaindole moiety.
Journal of medicinal chemistry 2003;46(4):609-22.
2003: Guillaumel Jean; Léonce Stéphane; Pierré Alain; Renard Pierre; Pfeiffer Bruno; Peruchon Laure; Arimondo Paola B; Monneret Claude
Synthesis and antiproliferative activity of basic ethers of 1,2-dihydropyrrolo[1,2-a]indole, 6H-isoindolo[2,1-a]indole, and 6H-benz[5,6]isoindolo[2,1-a]indole.
Oncology research 2003;13(12):537-49.
2003: Costes Nadine; Elomri Abdelhakim; Dufat Hanh; Michel Sylvie; Seguin Elisabeth; Koch Michel; Tillequin François; Pfeiffer Bruno; Renard Pierre; Léonce Stéphane; Pierré Alain
Synthesis of 6-dialkylaminoalkylamino pyrano[2,3-c]acridones and benzo[b]pyrano[3,2-h]acridones: soluble acronycine analogues with increased cytotoxic activity.
Oncology research 2003;13(4):191-7.
2002: Lisowski Vincent; Fabis Frédéric; Pierré Alain; Caignard Daniel-Henri; Renard Pierre; Rault Sylvain
Synthesis of new aromatic pyrrolo[2,1-c] [1,4]benzodiazepines and pyrrolo[1,2-a]thieno[3,2-e] [1,4]diazepines as anti-tumoral agents.
Journal of enzyme inhibition and medicinal chemistry 2002;17(6):403-7.
2002: Bermejo Almudena; Andreu Inmaculada; Suvire Fernando; Léonce Stephane; Caignard Daniel H; Renard Pierre; Pierré Alain; Enriz Ricardo D; Cortes Diego; Cabedo Nuria
Syntheses and antitumor targeting G1 phase of the cell cycle of benzoyldihydroisoquinolines and related 1-substituted isoquinolines.
Journal of medicinal chemistry 2002;45(23):5058-68.
2002: Fontana Alberto; Benito Enrique J; Martín M Justina; Sánchez Nuria; Alajarín Ramón; Vaquero J José; Alvarez-Builla Julio; Lambel-Giraudet Stéphanie; Leonce Stéphane; Pierré Alain; Caignard Daniel
Synthesis and cytotoxic activity of pyridazino[1',6':1,2]pyrido[3,4-b]indol-5-inium derivatives as anti-cancer agents.
Bioorganic & medicinal chemistry letters 2002;12(18):2611-4.
2002: Kraus-Berthier Laurence; Guilbaud Nicolas; Léonce Stéphane; Parker Tracy; Genissel Patrick; Guillonneau Claude; Goldstein Solo; Atassi Ghanem; Pierré Alain
Comparison of the pharmacological profile of an olivacine derivative and a potential prodrug.
Cancer chemotherapy and pharmacology 2002;50(2):95-103.
2002: David-Cordonnier Marie-Hélène; Laine William; Lansiaux Amélie; Kouach Mostafa; Briand Gilbert; Pierré Alain; Hickman John A; Bailly Christian
Alkylation of guanine in DNA by S23906-1, a novel potent antitumor compound derived from the plant alkaloid acronycine.
Biochemistry 2002;41(31):9911-20.
2002: Guilbaud Nicolas; Léonce Stéphane; Tillequin François; Koch Michel; Hickman John A; Pierré Alain
Acronycine derivatives as promising antitumor agents.
Anti-cancer drugs 2002;13(5):445-9.
2002: Kostakis Ioannis K; Magiatis Prokopios; Pouli Nicole; Marakos Panagiotis; Skaltsounis Alexios-Leandros; Pratsinis Harris; Léonce Stephane; Pierré Alain
Design, synthesis, and antiproliferative activity of some new pyrazole-fused amino derivatives of the pyranoxanthenone, pyranothioxanthenone, and pyranoacridone ring systems: a new class of cytotoxic agents.
Journal of medicinal chemistry 2002;45(12):2599-609.
2002: Perron-Sierra Françoise M; Pierré Alain; Burbridge Mike; Guilbaud Nicolas
Novel bicyclic oxazolone derivatives as anti-angiogenic agents.
Bioorganic & medicinal chemistry letters 2002;12(11):1463-6.
2002: Marminon Christelle; Facompré Michaël; Bailly Christian; Hickman John; Pierré Alain; Pfeiffer Bruno; Renard Pierre; Prudhomme Michelle
Dimers from dechlorinated rebeccamycin: synthesis, interaction with DNA, and antiproliferative activities.
European journal of medicinal chemistry 2002;37(5):435-40.
2002: Kluza Jérôme; Lansiaux Amélie; Wattez Nicole; Hildebrand Marie-Paule; Léonce Stéphane; Pierré Alain; Hickman John A; Bailly Christian
Induction of apoptosis in HL-60 leukemia and B16 melanoma cells by the acronycine derivative S23906-1.
Biochemical pharmacology 2002;63(8):1443-52.
2002: Marminon Christelle; Anizon Fabrice; Moreau Pascale; Léonce Stéphane; Pierré Alain; Pfeiffer Bruno; Renard Pierre; Prudhomme Michelle
Syntheses and antiproliferative activities of new rebeccamycin derivatives with the sugar unit linked to both indole nitrogens.
Journal of medicinal chemistry 2002;45(6):1330-9.
2002: Lewin Guy; Hocquemiller Reynald; Schaeffer Corinne; Lambert Pierre-Hervé; Léonce Stéphane; Pierré Alain
Cytotoxicity of 6,16-disubstituted analogues of (-)-vincadifformine.
Bioorganic & medicinal chemistry letters 2002;12(3):371-4.
2002: Martin Philippe; Rodier Stéphane; Mondon Martine; Renoux Brigitte; Pfeiffer Bruno; Renard Pierre; Pierré Alain; Gesson Jean Pierre
Synthesis and cytotoxic activity of tetracenomycin D and of saintopin analogues.
Bioorganic & medicinal chemistry 2002;10(2):253-60.
2001: Léonce S; Pérez V; Lambel S; Peyroulan D; Tillequin F; Michel S; Koch M; Pfeiffer B; Atassi G; Hickman J A; Pierré A
Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis.
Molecular pharmacology 2001;60(6):1383-91.
2001: Moreau P; Sancelme M; Bailly C; Léonce S; Pierré A; Hickman J; Pfeiffer B; Prudhomme M
Synthesis and biological activities of indolocarbazoles bearing amino acid residues.
European journal of medicinal chemistry 2001;36(11-12):887-97.
2001: Bongui J B; Elomri A; Seguin E; Tillequin F; Pfeiffer B; Renard P; Pierré A; Atassi G
Synthesis and cytotoxic activity of benzophenanthrolinone analogues of acronycine.
Chemical & pharmaceutical bulletin 2001;49(9):1077-80.
2001: Guilbaud N; Kraus-Berthier L; Meyer-Losic F; Malivet V; Chacun C; Jan M; Tillequin F; Michel S; Koch M; Pfeiffer B; Atassi G; Hickman J; Pierré A
Marked antitumor activity of a new potent acronycine derivative in orthotopic models of human solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2573-80.
2001: Sittisombut C; Costes N; Michel S; Koch M; Tillequin F; Pfeiffer B; Renard P; Pierré A; Atassi G
Synthesis and cytotoxic activity of benzopyranoxanthone analogues of benz.
Chemical & pharmaceutical bulletin 2001;49(6):675-9.
2001: Rodier S; Le Huerou Y; Renoux B; Doyon J; Renard P; Pierré A; Gesson J P; Grée R
New cytotoxic analogues of annonaceous acetogenins.
Anti-cancer drug design 2001;16(2-3):109-17.
2001: Melliou E; Magiatis P; Mitaku S; Skaltsounis A L; Pierré A; Atassi G; Renard P
2,2-Dimethyl-2H-anthra[2,3-b]pyran-6,11-diones: a new class of cytotoxic compounds.
Bioorganic & medicinal chemistry 2001;9(3):607-12.
2001: Chollet A M; Le Diguarher T; Murray L; Bertrand M; Tucker G C; Sabatini M; Pierré A; Atassi G; Bonnet J; Casara P
General synthesis of alpha-substituted 3-bisaryloxy propionic acid derivatives as specific MMP inhibitors.
Bioorganic & medicinal chemistry letters 2001;11(3):295-9.
2001: Guilbaud N; Kraus-Berthier L; Meyer-Losic F; Pierré A; Hickman J
[New approaches in experimental cancerology: in search of therapeutic models]
Bulletin du cancer 2001;88(1):75-84.
2001: Raoul M; Schaeffer C; Léonce S; Pierré A; Atassi G; Hocquemiller R; Lewin G
Synthesis of a novel series of cytotoxic bisindole alkaloids.
Bioorganic & medicinal chemistry letters 2001;11(1):79-81.
2000: Graf-Christophe S; Kuehm-Caubère C; Renard P; Pfeiffer B; Pierré A; Léonce S; Caubère P
Synthesis and antiproliferative activity of benzocyclobutacarbazol derivatives. A new class of potential antitumor agents.
Bioorganic & medicinal chemistry letters 2000;10(23):2589-91.
2000: Rodier S; Le Huérou Y; Renoux B; Doyon J; Renard P; Pierré A; Gesson J P; Grée R
Synthesis and cytotoxic activity of acetogenin analogues.
Bioorganic & medicinal chemistry letters 2000;10(12):1373-5.
2000: Costes N; Le Deit H; Michel S; Tillequin F; Koch M; Pfeiffer B; Renard P; Léonce S; Guilbaud N; Kraus-Berthier L; Pierré A; Atassi G
Synthesis and cytotoxic and antitumor activity of benzo[b]pyrano[3, 2-h]acridin-7-one analogues of acronycine.
Journal of medicinal chemistry 2000;43(12):2395-402.
2000: Kraus-Berthier L; Jan M; Guilbaud N; Naze M; Pierré A; Atassi G
Histology and sensitivity to anticancer drugs of two human non-small cell lung carcinomas implanted in the pleural cavity of nude mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(1):297-304.
1999: Elomri A; Michel S; Koch M; Seguin E; Tillequin F; Pierré A; Atassi G
Synthesis and cytotoxic activity of 11-nitro and 11-amino derivatives of acronycine and 6-demethoxyacronycine.
Chemical & pharmaceutical bulletin 1999;47(11):1604-6.
1999: Magiatis P; Mitaku S; Skaltsounis A L; Tillequin F; Koch M; Pierré A; Atassi G
Synthesis and cytotoxic activity of 1-alkoxy- and 1-amino-2-hydroxy-1,2-dihydroacronycine derivatives.
Chemical & pharmaceutical bulletin 1999;47(5):611-4.
1999: Costes N; Michel S; Tillequin F; Koch M; Pierré A; Atassi G
Chiral dihydroxylation of acronycine: absolute configuration of natural cis-1,2-dihydroxy-1,2-dihydroacronycine and cytotoxicity of (1R,2R)- and (1S,2S)-1,2-diacetoxy-1,2-dihydroacronycine.
Journal of natural products 1999;62(3):490-2.
1998: Magiatis P; Melliou E; Skaltsounis A L; Mitaku S; Léonce S; Renard P; Pierré A; Atassi G
Synthesis and cytotoxic activity of pyranocoumarins of the seselin and xanthyletin series.
Journal of natural products 1998;61(8):982-6.
1998: Costache E; Nguyen C H; Guilbaud N; Léonce S; Pierré A; Atassi G; Bisagni E
Synthesis, properties and biological evaluation of substituted furo[3,2-e] and pyrano[3,2-e]pyrido[4,3-b]indoles.
Anti-cancer drug design 1998;13(4):373-86.
1998: Costache E; Nguyen C H; Léonce S; Pierré A; Atassi G; Bisagni E
1-Amino-substituted 8-hydroxy-4,5-dimethyl-5H-pyrido[4,3-b]indoles with propyl- or methyl substituents at the 9-, and 7,9-positions: synthesis and biological evaluation.
Anti-cancer drug design 1998;13(4):361-72.
1998: Magiatis P; Mitaku S; Skaltsounis A L; Tillequin F; Koch M; Pierré A; Atassi G
Synthesis and biological activity of esters in the trans-1,2-dihydroxy-1,2-dihydroacronycine series.
Journal of natural products 1998;61(2):198-201.
1998: Razafimbelo J; Baudouin G; Tillequin F; Renard P; Léonce S; Pierré A; Atassi G
Synthesis and cytotoxic activity of pyranophenanthridine analogues of fagaronine and acronycine.
Chemical & pharmaceutical bulletin 1998;46(1):34-41.
1998: Pierré A; Léonce S; Pérez V; Atassi G
Circumvention of P-glycoprotein-mediated multidrug resistance by S16020-2: kinetics of uptake and efflux in sensitive and resistant cell lines.
Cancer chemotherapy and pharmacology 1998;42(6):454-60.
1997: Kraus-Berthier L; Guilbaud N; Jan M; Saint-Dizier D; Rouillon M H; Burbridge M F; Pierré A; Atassi G
Experimental antitumour activity of S 16020-2 in a panel of human tumours.
European journal of cancer (Oxford, England : 1990) 1997;33(11):1881-7.
1997: Morris A D; Léonce S; Guilbaud N; Tucker G C; Pérez V; Jan M; Cordi A A; Pierré A; Atassi G
Eriochrome Black T, structurally related to suramin, inhibits angiogenesis and tumor growth in vivo.
Anti-cancer drugs 1997;8(8):746-55.
1997: Guilbaud N; Kraus-Berthier L; Saint-Dizier D; Rouillon M H; Jan M; Burbridge M; Pierré A; Atassi G
Antitumor activity of S 16020-2 in two orthotopic models of lung cancer.
Anti-cancer drugs 1997;8(3):276-82.
1996: Landras C; Jasztold-Howorko R; Pierré A; Léonce S; Guilbaud N; Kraus-Berthier L; Guillonneau C; Rolland Y; Atassi G; Bisagni E
Synthesis and biological evaluation of 6-(9-hydroxy-5-methyl (and 5,6-dimethyl)-6H-pyrido[4,3-b]carbazol-1-yl)picolinic amides as new olivacine derivatives.
Chemical & pharmaceutical bulletin 1996;44(11):2169-72.
1996: Elomri A; Skaltsounis A L; Michel S; Tillequin F; Koch M; Rolland Y; Pierré A; Atassi G
Synthesis and cytotoxic activity of acronycine derivatives modified at the pyran ring.
Chemical & pharmaceutical bulletin 1996;44(11):2165-8.
1996: Elomri A; Mitaku S; Michel S; Skaltsounis A L; Tillequin F; Koch M; Pierré A; Guilbaud N; Léonce S; Kraus-Berthier L; Rolland Y; Atassi G
Synthesis and cytotoxic and antitumor activity of esters in the 1,2-dihydroxy-1,2-dihydroacronycine series.
Journal of medicinal chemistry 1996;39(24):4762-6.
1996: Mitaku S; Skaltsounis A L; Tillequin F; Koch M; Rolland Y; Pierré A; Atassi G
Synthesis and anti-proliferative activity of 2-hydroxy-1,2-dihydroacronycine glycosides.
Pharmaceutical research 1996;13(6):939-43.
1996: Léonce S; Perez V; Casabianca-Pignede M R; Anstett M; Bisagni E; Pierré A; Atassi G
In vitro cytotoxicity of S16020-2, a new olivacine derivative.
Investigational new drugs 1996;14(2):169-80.
1996: Guilbaud N; Kraus-Berthier L; Saint-Dizier D; Rouillon M H; Jan M; Burbridge M; Visalli M; Bisagni E; Pierré A; Atassi G
In vivo antitumor activity of S 16020-2, a new olivacine derivative.
Cancer chemotherapy and pharmacology 1996;38(6):513-21.
1995: Léonce S; Pierré A; Atassi G
Flow cytometric evaluation of multidrug-resistance circumvention.
Bulletin du cancer 1995;82(2):114-6.
1994: Jasztold-Howorko R; Landras C; Pierré A; Atassi G; Guilbaud N; Kraus-Berthier L; Léonce S; Rolland Y; Prost J F; Bisagni E
Synthesis and evaluation of 9-hydroxy-5-methyl-(and 5,6-dimethyl)-6H-pyrido[4,3-b]carbazole-1-N- [(dialkylamino)alkyl]carboxamides, a new promising series of antitumor olivacine derivatives.
Journal of medicinal chemistry 1994;37(15):2445-52.
1994: Demetzos C; Skaltsounis A L; Michel S; Tillequin F; Koch M; Anstett M; Leonce S; Pierré A; Atassi G
Synthesis and biological activity of 3'-deamino-3'-haloanthracyclines.
Anti-cancer drug design 1994;9(2):129-37.
1993: Moron J; Rautureau M; Huel C; Pierré A; Berthier L K; Atassi G; Bisagni E
Synthesis and evaluation of 4-amino-substituted 7-methoxy (and 7-hydroxy)- 11-methyl (and 5,11-dimethyl)-10H-pyrido [2,3-b] carbazoles and 4-amino- substituted 11-methyl (and 5,11-dimethyl)-10H-pyrido[3',4':4,5] pyrrolo [3,2-g] quinolines, two new series related to antitumor ellipticine derivatives.
Anti-cancer drug design 1993;8(6):399-416.
1993: Pérez V; Pierré A; Léonce S; Anstett M; Atassi G
Effect of duration of exposure to S9788, cyclosporin A or verapamil on sensitivity of multidrug resistant cells to vincristine or doxorubicin.
Anticancer research 1993;13(4):985-90.
1993: Pérez V; Pierré A; Léonce S; Anstett M; Prost J F; Atassi G
[In vitro characterization of S9788, a new modulator of multidrug resistance]
Bulletin du cancer 1993;80(4):310-25.
1992: Léonce S; Pierré A; Anstett M; Pérez V; Genton A; Bizzari J P; Atassi G
Effects of a new triazinoaminopiperidine derivative on adriamycin accumulation and retention in cells displaying P-glycoprotein-mediated multidrug resistance.
Biochemical pharmacology 1992;44(9):1707-15.
1992: Pierré A; Dunn T A; Kraus-Berthier L; Léonce S; Saint-Dizier D; Régnier G; Dhainaut A; Berlion M; Bizzari J P; Atassi G
In vitro and in vivo circumvention of multidrug resistance by Servier 9788, a novel triazinoaminopiperidine derivative.
Investigational new drugs 1992;10(3):137-48.
1992: Dhainaut A; Régnier G; Atassi G; Pierré A; Léonce S; Kraus-Berthier L; Prost J F
New triazine derivatives as potent modulators of multidrug resistance.
Journal of medicinal chemistry 1992;35(13):2481-96.
1992: Pierré A; Pérez V; Léonce S; Boutin J A; Saint-Dizier D; Hautefaye P; Lavielle G; Atassi G
Relationship between the cellular accumulation and the cytotoxicity of S12363, a new Vinca alkaloid derivative.
Cancer chemotherapy and pharmacology 1992;29(5):367-74.
1991: Lavielle G; Hautefaye P; Schaeffer C; Boutin J A; Cudennec C A; Pierré A
New alpha-amino phosphonic acid derivatives of vinblastine: chemistry and antitumor activity.
Journal of medicinal chemistry 1991;34(7):1998-2003.
1991: Pierré A; Kraus-Berthier L; Atassi G; Cros S; Poupon M F; Lavielle G; Berlion M; Bizzari J P
Preclinical antitumor activity of a new Vinca alkaloid derivative, S 12363.
Cancer research 1991;51(9):2312-8.
1990: Pierré A; Lavielle G; Hautefaye P; Seurre G; Leonce S; Saint-Dizier D; Boutin J A; Cudennec C A
Pharmacological properties of a new alpha-aminophosphonic acid derivative of vinblastine.
Anticancer research 1990;10(1):139-44.
1988: Bisagni E; Nguyen C H; Pierré A; Pépin O; de Cointet P; Gros P
1-Amino-substituted 4-methyl-5H-pyrido[4,3-b]indoles (gamma-carbolines) as tricyclic analogues of ellipticines: a new class of antineoplastic agents.
Journal of medicinal chemistry 1988;31(2):398-405.
1987: Nguyen C H; Bisagni E; Pepin O; Pierré A; de Cointet P
1-Amino-substituted 4-methyl-5H-pyrido[3',4':4,5]pyrrolo[3,2-c]pyridines: a new class of antineoplastic agents.
Journal of medicinal chemistry 1987;30(9):1642-7.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Alain Pierré

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Procedures

Concepts & Ideas

Disorders

Physiology

Genes & Molecular Sequences

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Alain Pierré (preview)

All Publications