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Rob Pieters

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TOP 3
Floor A M Duijkers; Jules P P Meijerink; Rob Pieters; Max M van Noesel
Downregulation of Axl in non-MYCN amplified neuroblastoma cell lines reduces migration.
W van Dorp; Jenny A Visser; Rob Pieters; L Stolk; A G Uitterlinden; Marry M van den Heuvel-Eibrink; J S E Laven
Genetic variation may modify ovarian reserve in female childhood cancer survivors.
J A P Spijkers-Hagelstein; S Mimoso Pinhanços; Rob Pieters; P Schneider; Ronald W Stam
Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.

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All Publications

2013: Floor A M Duijkers; Jules P P Meijerink; Rob Pieters; Max M van Noesel
Downregulation of Axl in non-MYCN amplified neuroblastoma cell lines reduces migration.
Gene 2013;521(1):62-8.
2013: W van Dorp; Jenny A Visser; Rob Pieters; L Stolk; A G Uitterlinden; Marry M van den Heuvel-Eibrink; J S E Laven
Genetic variation may modify ovarian reserve in female childhood cancer survivors.
Human reproduction (Oxford, England) 2013;28(4):1069-76.
2013: J A P Spijkers-Hagelstein; S Mimoso Pinhanços; Rob Pieters; P Schneider; Ronald W Stam
Src kinase-induced phosphorylation of annexin A2 mediates glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.
Leukemia 2013;27(5):1063-71.
2013: Karin Blijdorp; Rob Pieters; Marry van den Heuvel-Eibrink; Aart Jan Van der Lely; Marjolein van Waas; Sebastian Neggers
Endocrine sequelae and metabolic syndrome in adult long-term survivors of childhood acute myeloid leukemia.
Leukemia research 2013;37(4):367-71.
2013: Wendy van Dorp; Ivana M M van der Geest; Andrica C H De Vries; Wim C J Hop; Joop S E Laven; Sebastian J C M M Neggers; Rob Pieters; Marry M van den Heuvel-Eibrink
Gonadal function recovery in very long-term male survivors of childhood cancer.
European journal of cancer (Oxford, England : 1990) 2013;49(6):1280-6.
2013: M C H Hermkens; Rob Pieters; Dirk Reinhardt; Jan Stary; Marry M van den Heuvel-Eibrink; M Zimmerman; S T C J M Arentsen-Peters; A Baruchel; V de Haas; Christian M Zwaan
The clinical relevance of BAALC and ERG expression levels in pediatric AML.
Leukemia 2013;27(3):735-7.
2013: Annelies Hartman; Wim Hop; Rob Pieters; Tim Takken; Marry van den Heuvel-Eibrink
Motor performance and functional exercise capacity in survivors of pediatric acute lymphoblastic leukemia.
Pediatric blood & cancer 2013;60(3):494-9.
2013: Anna M Aalbers; Andre Baruchel; Rodrigo T Calado; Valerie de Haas; Karin Geleijns; Sachiko Kajigaya; Gertjan J L Kaspers; Taco W Kuijpers; Rob Pieters; Dirk Reinhardt; Jan Trka; Vincent H J van der Velden; Neal S Young; C Michel Zwaan; Marry M van den Heuvel-Eibrink
Absence of SBDS mutations in sporadic paediatric acute myeloid leukaemia.
British journal of haematology 2013;160(4):559-61.
2013: Marjolein van Waas; Ivana M M van der Geest; Karin Blijdorp; Sebastian J C M M Neggers; Rob Pieters; André G Uitterlinden; Marry M van den Heuvel-Eibrink
Treatment factors rather than genetic variation determine metabolic syndrome in childhood cancer survivors.
European journal of cancer (Oxford, England : 1990) 2013;49(3):668-75.
2013: Wing H Tong; Joachim Boos; Wim C J Hop; Claudia Lanvers-Kaminsky; Rob Pieters; Inge M van der Sluis
No evidence of increased asparagine levels in the bone marrow of patients with acute lymphoblastic leukemia during asparaginase therapy.
Pediatric blood & cancer 2013;60(2):258-61.
2013: Heidi Segers; Marry M van den Heuvel-Eibrink; Anja Wagner; Ronald R de Krijger; Rob Pieters; Winand N M Dinjens
Defects in the DNA mismatch repair system do not contribute to the development of childhood wilms tumors.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2013;16(1):14-9.
2013: Dominique J P M Stumpel; Eddy H J van Roon; Rob Pieters; Pauline Schneider; Ronald W Stam
Absence of global hypomethylation in promoter hypermethylated Mixed Lineage Leukaemia-rearranged infant acute lymphoblastic leukaemia.
European journal of cancer (Oxford, England : 1990) 2013;49(1):175-84.
2013: T D Buitenkamp; V de Haas; Christine J Harrison; C D Mitchell; A V Moorman; Rob Pieters; Susan M Richards; C Schwab; Marry M van den Heuvel-Eibrink; Ajay J Vora; Martin Zimmermann; Christian M Zwaan
BTG1 deletions do not predict outcome in Down syndrome acute lymphoblastic leukemia.
Leukemia 2013;27(1):251-2.
2013: F Akbari Moqadam; Rob Pieters; Monique L den Boer
The hunting of targets: challenge in miRNA research.
Leukemia 2013;27(1):16-23.
2012: Eva A Coenen; Eveline S J M de Bont; Valerie de Haas; Emma M C Driessen; G J L Kaspers; Rolf Marschalek; Claus Meyer; Rob Pieters; Dirk Reinhardt; Ronald W Stam; Jan Stary; Susan T C J M Arentsen-Peters; Andre Baruchel; Christian M Zwaan; Marry M van den Heuvel-Eibrink
CBL mutations do not frequently occur in paediatric acute myeloid leukaemia.
British journal of haematology 2012;159(5):577-84.
2012: Saskia L Gooskens; Rob Pieters; Cynthia So-Osman; Anne Loes van den Boom; Eric Braakman; Ferdinand de Winter; Marry M van den Heuvel-Eibrink
Peripheral stem cell harvest using regular chemotherapy schedules in childhood cancer.
Pediatric transplantation 2012;16(7):758-65.
2012: H Segers; Marielle Alders; Rogier Kersseboom; Rob Pieters; Anja Wagner; Marry M van den Heuvel-Eibrink
Frequency of WT1 and 11p15 constitutional aberrations and phenotypic correlation in childhood Wilms tumour patients.
European journal of cancer (Oxford, England : 1990) 2012;48(17):3249-56.
2012: T D Buitenkamp; V de Haas; Monique L den Boer; N E Gallimore; Christine J Harrison; Jules P P Meijerink; C D Mitchell; A V Moorman; Rob Pieters; Susan M Richards; L J Russell; C Schwab; Marry M van den Heuvel-Eibrink; A van der Veer; Ajay J Vora; Martin Zimmermann; Berna Beverloo; Christian M Zwaan
Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations.
Leukemia 2012;26(10):2204-11.
2012: Karin Blijdorp; Annemieke Boot; Rob Pieters; Johanna Sluimer; Marry van den Heuvel-Eibrink; Aart-Jan van der Lelij; Sebastian Neggers
The limited screening value of insulin-like growth factor-I as a marker for alterations in body composition in very long-term adult survivors of childhood cancer.
Pediatric blood & cancer 2012;59(4):711-6.
2012: Marry M van den Heuvel-Eibrink; Rob Pieters
Steroids and risk of osteonecrosis in ALL: take a break.
The lancet oncology 2012;13(9):855-7.
2012: Marjolein Blink; Rodrigo T Calado; Valerie de Haas; Henrik Hasle; Iris H I M Hollink; Jan-Henning Klusmann; Jules P P Meijerink; Rob Pieters; Dirk Reinhardt; Marry M van den Heuvel-Eibrink; V H J van der Velden; Anna M Aalbers; Brian Balgobind; Berna H Beverloo; Christian M Zwaan
High frequency of copy number alterations in myeloid leukaemia of Down syndrome.
British journal of haematology 2012;158(6):800-3.
2012: Linda Zuurbier; Jessica G C A M Buijs-Gladdines; Valerie Calvert; Martin Horstmann; Willem A Kamps; Clarissa Kooi; Emanuel F Petricoin; Rob Pieters; Willem K Smits; Edwin Sonneveld; Anjo J P Veerman; Maartje J Vuerhard; Jules P P Meijerink
The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia.
Haematologica 2012;97(9):1405-13.
2012: Marieke H van der Linden; Sara Creemers; Rob Pieters
Diagnosis and management of neonatal leukaemia.
Seminars in fetal & neonatal medicine 2012;17(4):192-5.
2012: J A P Spijkers-Hagelstein; O Williams; J de Boer; E Hulleman; Rob Pieters; P Schneider; Ronald W Stam
Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia.
Leukemia 2012;26(6):1255-65.
2012: M van Waas; A Beishuizen; Sebastian J C M M Neggers; Rob Pieters; M L Te Winkel; Marry M van den Heuvel-Eibrink
Endocrine late sequelae in long-term survivors of childhood non-Hodgkin lymphoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(6):1626-32.
2012: Marjolein van Waas; Aart Jan Van der Lely; Judith P van Eck; Max M van Noesel; Frank H de Jong; Sebastian J C M M Neggers; Rob Pieters; Marry M van den Heuvel-Eibrink
Adrenal function in adult long-term survivors of nephroblastoma and neuroblastoma.
European journal of cancer (Oxford, England : 1990) 2012;48(8):1159-66.
2012: Eva A Coenen; Ursula Creutzig; Rolf Marschalek; Claus Meyer; Rob Pieters; Jutta Bradtke; Christian M Zwaan; Marry M van den Heuvel-Eibrink
Abl-interactor 2 (ABI2): a novel MLL translocation partner in acute myeloid leukemia.
Leukemia research 2012;36(5):e113-5.
2012: Astrid A Danen-van Oorschot; Valerie de Haas; Jenny E Kuipers; Rob Pieters; Dirk Reinhardt; Diana Schotte; Jan Trka; Susan Arentsen-Peters; André Baruchel; C Michel Zwaan; Marry M van den Heuvel-Eibrink
Differentially expressed miRNAs in cytogenetic and molecular subtypes of pediatric acute myeloid leukemia.
Pediatric blood & cancer 2012;58(5):715-21.
2012: CM van Tilburg; Tom F W Wolfs; Guy A M Berbers; Marc Bierings; Andries C Bloem; Rob Pieters; Elisabeth A M Sanders
Impact of treatment reduction for childhood acute lymphoblastic leukemia on serum immunoglobulins and antibodies against vaccine-preventable diseases.
Pediatric blood & cancer 2012;58(5):701-7.
2012: I Homminga; Rob Pieters; Jules P P Meijerink
NKL homeobox genes in leukemia.
Leukemia 2012;26(4):572-81.
2012: D J P M Stumpel; O Williams; H Osaki; Rob Pieters; P Schneider; L Seslija; Ronald W Stam
Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia.
Leukemia 2012;26(4):682-92.
2012: Stephan Borghorst; Hans-Juergen Kuehnel; Rob Pieters; Joachim Boos; Georg Hempel
Population pharmacokinetics of native Escherichia coli asparaginase.
Pediatric hematology and oncology 2012;29(2):154-65.
2012: Floor A M Duijkers; José Gaal; Jules P P Meijerink; Rob Pieters; Pieter Admiraal; Ronald R de Krijger; Max M van Noesel
High anaplastic lymphoma kinase immunohistochemical staining in neuroblastoma and ganglioneuroblastoma is an independent predictor of poor outcome.
The American journal of pathology 2012;180(3):1223-31.
2012: I H I M Hollink; Rob Pieters; Dirk Reinhardt; Jan Trka; Marry M van den Heuvel-Eibrink; L J Verboon; J Wang; P Zhang; S T C J M Arentsen-Peters; Ursula Creutzig; A A Danen-van Oorschot; V de Haas; Q Feng; Christian M Zwaan
Low frequency of DNMT3A mutations in pediatric AML, and the identification of the OCI-AML3 cell line as an in vitro model.
Leukemia 2012;26(2):371-3.
2012: Marjolein van Waas; Caroline M van Rij; Sebastian J C M M Neggers; Rob Pieters; Hein Raat; Marry M van den Heuvel-Eibrink
Abdominal radiotherapy: a major determinant of metabolic syndrome in nephroblastoma and neuroblastoma survivors.
PloS one 2012;7(12):e52237.
2012: Karin Blijdorp; Annemieke M Boot; Patric J D Delhanty; Rob Pieters; Marry M van den Heuvel-Eibrink; Aart Jan Van der Lely; Sebastian J C M M Neggers
Obesity is underestimated using body mass index and waist-hip ratio in long-term adult survivors of childhood cancer.
PloS one 2012;7(8):e43269.
2012: Kris Boudestein; Willem A Kamps; Anjo J P Veerman; Rob Pieters
Different outcome in older children with acute lymphoblastic leukemia with different treatment protocols in the Netherlands.
Pediatric blood & cancer 2012;58(1):17-22.
2011: Mariël L te Winkel; Inge M van der Sluis; Anjo J P Veerman; Jos P M Bökkerink; Marrie Bruin; Hester A de Groot-Kruseman; R Maarten Egeler; Wim C J Hop; Jan A Leeuw; Maarten H Lequin; Rob Pieters; Marry M van den Heuvel-Eibrink
Prospective study on incidence, risk factors, and long-term outcome of osteonecrosis in pediatric acute lymphoblastic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(31):4143-50.
2011: Brian Balgobind; Andre Baruchel; Berna Beverloo; Jean-Michel Cayuela; Jacqueline Cloos; Ursula Creutzig; Valerie de Haas; Jochen Harbott; Iris H I M Hollink; G J L Kaspers; Rob Pieters; Dirk Reinhardt; Jan Stary; Anne R M von Bergh; Zuzana Zemanova; Martin Zimmermann; Christian M Zwaan; Susan T C J M Arentsen-Peters; Marry M van den Heuvel-Eibrink
Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia.
Haematologica 2011;96(10):1478-87.
2011: Floor A M Duijkers; José Gaal; Jules P P Meijerink; Rob Pieters; Pieter Admiraal; Ronald R de Krijger; Max M van Noesel
Anaplastic lymphoma kinase (ALK) inhibitor response in neuroblastoma is highly correlated with ALK mutation status, ALK mRNA and protein levels.
Cellular oncology (Dordrecht) 2011;34(5):409-17.
2011: Iris H I M Hollink; Gert-Jan J L Kaspers; Jenny E Kuipers; Rob Pieters; Marta Pratcorona; Dirk Reinhardt; Edwin Sonneveld; Jan Trka; Peter J M Valk; Marry M van den Heuvel-Eibrink; Janneke F van Galen; Martin Zimmermann; Saman Abbas; Susan T C J M Arentsen-Peters; Andre Baruchel; Berna Beverloo; Ursula Creutzig; Christian M Zwaan
NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern.
Blood 2011;118(13):3645-56.
2011: D Schotte; W F J van Ijcken; F Akbari Moqadam; C Chen; E A M Lange-Turenhout; Rob Pieters; Monique L den Boer
Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia.
Leukemia 2011;25(9):1389-99.
2011: Irene Homminga; Chantal Y Manz; Shanta Bantia; Fiona Higginbotham; Cynthia Parker; Rob Pieters; Willem Korstiaan Smits; Christian M Zwaan; Jules P P Meijerink
In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia.
Blood 2011;118(8):2184-90.
2011: E Wieten; E Sonneveld; B E M van der Linden-Schrever; Anjo J P Veerman; Rob Pieters
CD73 (5'-nucleotidase) expression has no prognostic value in children with acute lymphoblastic leukemia.
Leukemia 2011;25(8):1374-6.
2011: Brian Balgobind; Rob Pieters; Christian M Zwaan; Marry M van den Heuvel-Eibrink
The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia.
Leukemia 2011;25(8):1239-48.
2011: M Blink; T D Buitenkamp; A J Carroll; A A Danen-van Oorschot; V de Haas; Meenakshi Devidas; H Hasle; S Izraeli; Jan-Henning Klusmann; A Pession; Rob Pieters; Karen Rabin; Dirk Reinhardt; Marry M van den Heuvel-Eibrink; Martin Zimmermann; G Basso; Christian M Zwaan
Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia.
Leukemia 2011;25(8):1365-8.
2011: Gabriele Escherich; Ulrich Göbel; Ulrike B Graubner; Martin Horstmann; Gritta Janka; Norbert Jorch; G J L Kaspers; Karin Kazemier; Arnulf Pekrun; Rob Pieters; Anja Tröger; Martin Zimmermann; Udo zur Stadt; Monique L den Boer
The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).
Haematologica 2011;96(6):854-62.
2011: Diana Schotte; Renée X de Menezes; Leila Mohammadi Khankahdani; Ellen Lange-Turenhout; Caifu Chen; Rob Pieters; Farhad Akbari Moqadam; Monique L den Boer
MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia.
Haematologica 2011;96(5):703-11.
2011: Irene Homminga; Rob Pieters; Anton W Langerak; Johan J de Rooi; Andrew Stubbs; Monique Verstegen; Maartje Vuerhard; Jessica Buijs-Gladdines; Clarissa Kooi; Petra Klous; Pieter Van Vlierberghe; Adolfo Ferrando; Jean Michel Cayuela; Brenda Verhaaf; Berna Beverloo; Martin Horstmann; Valerie de Haas; Anna-Sophia Wiekmeijer; Karin Pike-Overzet; Frank Staal; Wouter de Laat; Jean Soulier; Francois Sigaux; Jules P P Meijerink
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.
Cancer cell 2011;19(4):484-97.
2011: Cornelis M van Tilburg; Vincent H J van der Velden; Elisabeth A M Sanders; Tom F W Wolfs; Jacobus F Gaiser; Valerie de Haas; Rob Pieters; Andries C Bloem; Marc B Bierings
Reduced versus intensive chemotherapy for childhood acute lymphoblastic leukemia: impact on lymphocyte compartment composition.
Leukemia research 2011;35(4):484-91.
2011: D J P M Stumpel; D Schotte; E A M Lange-Turenhout; P Schneider; L Seslija; Renée X de Menezes; V E Marquez; Rob Pieters; Monique L den Boer; Ronald W Stam
Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale.
Leukemia 2011;25(3):429-39.
2011: M L te Winkel; Sabine M P F de Muinck Keizer-Schrama; R de Jonge; Robert D van Beek; Inge M van der Sluis; W C J Hop; Rob Pieters; Marry M van den Heuvel-Eibrink
Germline variation in the MTHFR and MTRR genes determines the nadir of bone density in pediatric acute lymphoblastic leukemia: a prospective study.
Bone 2011;48(3):571-7.
2011: CM van Tilburg; Elisabeth A M Sanders; Elisabeth E Nibbelke; Rob Pieters; Tom Revesz; Paul Westers; Tom F W Wolfs; Marc Bierings
Impact of reduced chemotherapy treatment for good risk childhood acute lymphoblastic leukaemia on infectious morbidity*.
British journal of haematology 2011;152(4):433-40.
2011: Brian Balgobind; Marry M van den Heuvel-Eibrink; Renee X De Menezes; Dirk Reinhardt; Iris H I M Hollink; Susan T J C M Arentsen-Peters; Elisabeth R van Wering; Gertjan J L Kaspers; Jacqueline Cloos; Eveline S J M de Bont; Jean-Michel Cayuela; Andre Baruchel; Claus Meyer; Rolf Marschalek; Jan Trka; Jan Stary; Berna Beverloo; Rob Pieters; Christian M Zwaan; Monique L den Boer
Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia.
Haematologica 2011;96(2):221-30.
2011: Jenny E Kuipers; Eva A Coenen; Brian Balgobind; Jan Stary; Andre Baruchel; Valerie de Haas; Eveline S J M de Bont; Dirk Reinhardt; G J L Kaspers; Jacqueline Cloos; Astrid A Danen-van Oorschot; Monique L den Boer; Rolf Marschalek; Claus Meyer; Rob Pieters; Christian M Zwaan; Marry M van den Heuvel-Eibrink
High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).
Blood 2011;117(3):928-35.
2011: Rob Pieters; Stephen P Hunger; Joachim Boos; Carmelo Rizzari; Lewis Silverman; Andre Baruchel; Nicola Goekbuget; Martin Schrappe; Ching-Hon Pui
L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase.
Cancer 2011;117(2):238-49.
2011: Eva A Coenen; Christian M Zwaan; Claus Meyer; Rolf Marschalek; Rob Pieters; Lars T van der Veken; Berna Beverloo; Marry M van den Heuvel-Eibrink
KIAA1524: A novel MLL translocation partner in acute myeloid leukemia.
Leukemia research 2011;35(1):133-5.
2010: Brian Balgobind; Christian M Zwaan; Dirk Reinhardt; T J C M Arentsen-Peters; I H I M Hollink; V de Haas; G J L Kaspers; Eveline S J M de Bont; A Baruchel; Jan Stary; Claus Meyer; Rolf Marschalek; Ursula Creutzig; Monique L den Boer; Rob Pieters; Marry M van den Heuvel-Eibrink
High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome.
Leukemia 2010;24(12):2048-55.
2010: L Zuurbier; I Homminga; V Calvert; M L te Winkel; J G C A M Buijs-Gladdines; C Kooi; W K Smits; E Sonneveld; A J P Veerman; Willem A Kamps; Martin Horstmann; E F Petricoin; Rob Pieters; Jules P P Meijerink
NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.
Leukemia 2010;24(12):2014-22.
2010: Diana Schotte; Ellen A M Lange-Turenhout; Dominique J P M Stumpel; Ronald W Stam; Jessica G C A M Buijs-Gladdines; Jules P P Meijerink; Rob Pieters; Monique L den Boer
Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia.
Haematologica 2010;95(10):1675-82.
2010: M L te Winkel; Maarten H Lequin; J R de Bruyn; C P van de Ven; Ronald R de Krijger; Rob Pieters; Marry M van den Heuvel-Eibrink
Self-limiting sternal tumors of childhood (SELSTOC).
Pediatric blood & cancer 2010;55(1):81-4.
2010: Trudy D Buitenkamp; Ron A A Mathôt; Valerie de Haas; Rob Pieters; Christian M Zwaan
Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia.
Haematologica 2010;95(7):1106-13.
2010: Brian Balgobind; Iris H I M Hollink; Dirk Reinhardt; Elisabeth R van Wering; Siebold S N de Graaf; Andre Baruchel; Jan Stary; Berna Beverloo; Georgine E De Greef; Rob Pieters; Christian M Zwaan; Marry M van den Heuvel-Eibrink
Low frequency of MLL-partial tandem duplications in paediatric acute myeloid leukaemia using MLPA as a novel DNA screenings technique.
European journal of cancer (Oxford, England : 1990) 2010;46(10):1892-9.
2010: Rob Pieters
Childhood leukaemia: towards improved tailored therapy.
The lancet oncology 2010;11(5):403-4.
2010: Brian Balgobind; S Lugthart; I H Hollink; S T J C M Arentsen-Peters; Elisabeth R van Wering; Siebold S N de Graaf; Dirk Reinhardt; Ursula Creutzig; G J L Kaspers; E S J M de Bont; Jan Stary; Jan Trka; M Zimmermann; Berna Beverloo; Rob Pieters; Ruud Delwel; Christian M Zwaan; Marry M van den Heuvel-Eibrink
EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia.
Leukemia 2010;24(5):942-9.
2010: Mariël L te Winkel; Robert D van Beek; Sabine M P F de Muinck Keizer-Schrama; André G Uitterlinden; Wim C J Hop; Rob Pieters; Marry M van den Heuvel-Eibrink
Pharmacogenetic risk factors for altered bone mineral density and body composition in pediatric acute lymphoblastic leukemia.
Haematologica 2010;95(5):752-9.
2010: M van Waas; S J C M M Neggers; Rob Pieters; Marry M van den Heuvel-Eibrink
Components of the metabolic syndrome in 500 adult long-term survivors of childhood cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2010;21(5):1121-6.
2010: Ronald W Stam; Pauline Schneider; Jill A P Hagelstein; Marieke H van der Linden; Dominique J P M Stumpel; Renée X de Menezes; Paola de Lorenzo; Maria Grazia Valsecchi; Rob Pieters
Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants.
Blood 2010;115(14):2835-44.
2010: Marjolein van Waas; Sebastian J Neggers; Aart-Jan van der Lelij; Rob Pieters; Marry M van den Heuvel-Eibrink
The metabolic syndrome in adult survivors of childhood cancer, a review.
Journal of pediatric hematology/oncology 2010;32(3):171-9.
2010: Ronald W Stam; Monique L den Boer; Pauline Schneider; Jasper de Boer; Jill Hagelstein; Maria Grazia Valsecchi; Paola de Lorenzo; Stephen E Sallan; Hugh J M Brady; Scott A Armstrong; Rob Pieters
Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia.
Blood 2010;115(5):1018-25.
2010: Rob Pieters; William L Carroll
Biology and treatment of acute lymphoblastic leukemia.
Hematology/oncology clinics of North America 2010;24(1):1-18.
2010: A Hartman; Ron van Schaik; Ilse P van der Heiden; M J C Broekhuis; M Meier; Monique L den Boer; Rob Pieters
Polymorphisms in genes involved in vincristine pharmacokinetics or pharmacodynamics are not related to impaired motor performance in children with leukemia.
Leukemia research 2010;34(2):154-9.
2009: Dominique J P M Stumpel; Pauline Schneider; Eddy H J van Roon; Judith M Boer; Paola de Lorenzo; Maria Grazia Valsecchi; Renée X de Menezes; Rob Pieters; Ronald W Stam
Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options.
Blood 2009;114(27):5490-8.
2009: Marieke H van der Linden; Maria Grazia Valsecchi; Paola de Lorenzo; Anja Möricke; Gritta Janka; Thierry Leblanc; Maria Felice; Andrea Biondi; Myriam Campbell; Ian Hann; Jeffrey E Rubnitz; Jan Stary; Tomasz Szczepanski; Ajay Vora; Alina Ferster; Liisa Hovi; Lewis B Silverman; Rob Pieters
Outcome of congenital acute lymphoblastic leukemia treated on the Interfant-99 protocol.
Blood 2009;114(18):3764-8.
2009: Esther Hulleman; Mathilde J C Broekhuis; Rob Pieters; Monique L den Boer
Pyruvate kinase M2 and prednisolone resistance in acute lymphoblastic leukemia.
Haematologica 2009;94(9):1322-4.
2009: Rob Pieters
Infant acute lymphoblastic leukemia: Lessons learned and future directions.
Current hematologic malignancy reports 2009;4(3):167-74.
2009: Annelies Hartman; M L te Winkel; Robert D van Beek; Sabine M P F de Muinck Keizer-Schrama; Han CG Kemper; W C J Hop; Marry M van den Heuvel-Eibrink; Rob Pieters
A randomized trial investigating an exercise program to prevent reduction of bone mineral density and impairment of motor performance during treatment for childhood acute lymphoblastic leukemia.
Pediatric blood & cancer 2009;53(1):64-71.
2009: Iris H I M Hollink; Marry M van den Heuvel-Eibrink; Martin Zimmermann; Brian Balgobind; Susan T C J M Arentsen-Peters; Marielle Alders; Andre Willasch; G J L Kaspers; Jan Trka; Andre Baruchel; Siebold S N de Graaf; Ursula Creutzig; Rob Pieters; Dirk Reinhardt; Christian M Zwaan
Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia.
Blood 2009;113(23):5951-60.
2009: Robert D van Beek; Marry M van den Heuvel-Eibrink; Friederike G A J Hakvoort-Cammel; Cor van den Bos; Heleen J H van der Pal; Eric P Krenning; Yolanda B De Rijke; Rob Pieters; Sabine M P F de Muinck Keizer-Schrama
Bone mineral density, growth, and thyroid function in long-term survivors of pediatric Hodgkin's lymphoma treated with chemotherapy only.
The Journal of clinical endocrinology and metabolism 2009;94(6):1904-9.
2009: V H J van der Velden; L Corral; Maria Grazia Valsecchi; M W J C Jansen; Paola de Lorenzo; Giovanni Cazzaniga; E Renate Panzer-Grümayer; Martin Schrappe; André Schrauder; Claus Meyer; Rolf Marschalek; L L Nigro; M Metzler; G Basso; G Mann; Monique L den Boer; A Biondi; Rob Pieters; J J M Van Dongen
Prognostic significance of minimal residual disease in infants with acute lymphoblastic leukemia treated within the Interfant-99 protocol.
Leukemia 2009;23(6):1073-9.
2009: Robert de Jonge; Wim J E Tissing; Jan Hendrik Hooijberg; Gerrit Jansen; G J L Kaspers; Jan Lindemans; Godefridus J Peters; Rob Pieters
Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia.
Blood 2009;113(10):2284-9.
2009: Esther Hulleman; Karin M Kazemier; Amy Holleman; David J VanderWeele; Charles Rudin; Mathilde J C Broekhuis; William Evans; Rob Pieters; Monique L den Boer
Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells.
Blood 2009;113(9):2014-21.
2009: Monique L den Boer; Marjon van Slegtenhorst; Renée X de Menezes; Meyling H Cheok; Jessica G C A M Buijs-Gladdines; Susan T C J M Peters; Laura J C M Van Zutven; Berna Beverloo; Peter van der Spek; Gaby Escherich; Martin A Horstmann; Gritta E Janka-Schaub; Willem A Kamps; William Evans; Rob Pieters
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study.
The lancet oncology 2009;10(2):125-34.
2009: I H I M Hollink; Christian M Zwaan; M Zimmermann; T C J M Arentsen-Peters; Rob Pieters; J Cloos; G J L Kaspers; Siebold S N de Graaf; J Harbott; U Creutzig; Dirk Reinhardt; Marry M van den Heuvel-Eibrink; C Thiede
Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML.
Leukemia 2009;23(2):262-70.
2009: D Schotte; J C K Chau; G Sylvester; G Liu; C Chen; V H J van der Velden; M J C Broekhuis; T C J M Peters; Rob Pieters; Monique L den Boer
Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia.
Leukemia 2009;23(2):313-22.
2008: Rob Pieters; Inge M Appel; Hans-Juergen Kuehnel; Iris Tetzlaff-Fohr; Uwe Pichlmeier; Inekee van der Vaart; Eline Visser; Rolinda Stigter
Pharmacokinetics, pharmacodynamics, efficacy, and safety of a new recombinant asparaginase preparation in children with previously untreated acute lymphoblastic leukemia: a randomized phase 2 clinical trial.
Blood 2008;112(13):4832-8.
2008: Martine van Grotel; Marry M van den Heuvel-Eibrink; Elisabeth R van Wering; Max M van Noesel; Willem A Kamps; Anjo J P Veerman; Rob Pieters; Jules P P Meijerink
CD34 expression is associated with poor survival in pediatric T-cell acute lymphoblastic leukemia.
Pediatric blood & cancer 2008;51(6):737-40.
2008: Mariel L te Winkel; Inge M Appel; Rob Pieters; Marry M van den Heuvel-Eibrink
Impaired dexamethasone-related increase of anticoagulants is associated with the development of osteonecrosis in childhood acute lymphoblastic leukemia.
Haematologica 2008;93(10):1570-4.
2008: Pieter Van Vlierberghe; Rob Pieters; Berna Beverloo; Jules P P Meijerink
Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia.
British journal of haematology 2008;143(2):153-68.
2008: Judith M de Bont; Johan M Kros; Monique Passier; Roel E Reddingius; Peter A E Sillevis Smitt; Theo M Luider; Monique L den Boer; Rob Pieters
Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis.
Neuro-oncology 2008;10(5):648-60.
2008: Inge M Appel; Karin M Kazemier; Joachim Boos; C Lanvers; J Huijmans; Anjo J P Veerman; Elisabeth R van Wering; Monique L den Boer; Rob Pieters
Pharmacokinetic, pharmacodynamic and intracellular effects of PEG-asparaginase in newly diagnosed childhood acute lymphoblastic leukemia: results from a single agent window study.
Leukemia 2008;22(9):1665-79.
2008: Eric G Haarman; G J L Kaspers; Rob Pieters; M M A Rottier; Anjo J P Veerman
Circumvention of glucocorticoid resistance in childhood leukemia.
Leukemia research 2008;32(9):1417-23.
2008: Inge M Appel; Wim C J Hop; Carla van Kessel-Bakvis; Rolinda Stigter; Rob Pieters
L-Asparaginase and the effect of age on coagulation and fibrinolysis in childhood acute lymphoblastic leukemia.
Thrombosis and haemostasis 2008;100(2):330-7.
2008: Judith M de Bont; Jaap van Doorn; Roel E Reddingius; Gerard H M Graat; Monique Passier; Monique L den Boer; Rob Pieters
Various components of the insulin-like growth factor system in tumor tissue, cerebrospinal fluid and peripheral blood of pediatric medulloblastoma and ependymoma patients.
International journal of cancer. Journal international du cancer 2008;123(3):594-600.
2008: Christoph le Viseur; Marc Hotfilder; Simon Bomken; Kerrie Wilson; Silja Röttgers; André Schrauder; Annegret Rosemann; Julie Irving; Ronald W Stam; Leonard D Shultz; Jochen Harbott; Heribert Jürgens; Martin Schrappe; Rob Pieters; Josef Vormoor
In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties.
Cancer cell 2008;14(1):47-58.
2008: Judith M de Bont; hugo vanderstichele; Roel E Reddingius; Rob Pieters; Stefaan W Van Gool
Increased total-Tau levels in cerebrospinal fluid of pediatric hydrocephalus and brain tumor patients.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 2008;12(4):334-41.
2008: A C H de Vries; Anton Langerak; Brenda Verhaaf; C M Niemeyer; Jan Stary; Kjeld Schmiegelow; Elisabeth R van Wering; Christian M Zwaan; Auke Beishuizen; Rob Pieters; Marry M van den Heuvel-Eibrink
T-cell receptor Vbeta CDR3 oligoclonality frequently occurs in childhood refractory cytopenia (MDS-RC) and severe aplastic anemia.
Leukemia 2008;22(6):1170-4.
2008: Pieter Van Vlierberghe; Martine van Grotel; Joëlle Tchinda; Charles Lee; Berna Beverloo; Peter van der Spek; Andrew Stubbs; Jan Cools; Kyosuke Nagata; Maarten Fornerod; Jessica Buijs-Gladdines; Martin Horstmann; Elisabeth R van Wering; Jean Soulier; Rob Pieters; Jules P P Meijerink
The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia.
Blood 2008;111(9):4668-80.
2008: Brian Balgobind; Pieter Van Vlierberghe; Ans M W van den Ouweland; Berna Beverloo; Joan N R Terlouw-Kromosoeto; Elisabeth R van Wering; Dirk Reinhardt; Martin Horstmann; G J L Kaspers; Rob Pieters; Christian M Zwaan; Marry M van den Heuvel-Eibrink; Jules P P Meijerink
Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis.
Blood 2008;111(8):4322-8.
2008: Pieter Van Vlierberghe; I Homminga; L Zuurbier; J Gladdines-Buijs; Elisabeth R van Wering; Martin Horstmann; Berna Beverloo; Rob Pieters; Jules P P Meijerink
Cooperative genetic defects in TLX3 rearranged pediatric T-ALL.
Leukemia 2008;22(4):762-70.
2008: Annelies Hartman; Cor van den Bos; Theo Stijnen; Rob Pieters
Decrease in peripheral muscle strength and ankle dorsiflexion as long-term side effects of treatment for childhood cancer.
Pediatric blood & cancer 2008;50(4):833-7.
2008: Rob Pieters; William L Carroll
Biology and treatment of acute lymphoblastic leukemia.
Pediatric clinics of North America 2008;55(1):1-20, ix.
2008: Martine van Grotel; Jules P P Meijerink; Elisabeth R van Wering; Anton Langerak; Berna Beverloo; J G C A M Buijs-Gladdines; N B Burger; Monique Passier; E M van Lieshout; Willem A Kamps; Anjo J P Veerman; Max M van Noesel; Rob Pieters
Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences.
Leukemia 2008;22(1):124-31.
2007: Robert D van Beek; Marij Smit; Marry M van den Heuvel-Eibrink; Frank de Jong; Friederike G A J Hakvoort-Cammel; Cor van den Bos; Henk van den Berg; R F A Weber; Rob Pieters; Sabine M P F de Muinck Keizer-Schrama
Inhibin B is superior to FSH as a serum marker for spermatogenesis in men treated for Hodgkin's lymphoma with chemotherapy during childhood.
Human reproduction (Oxford, England) 2007;22(12):3215-22.
2007: Ronald W Stam; Monique L den Boer; Pauline Schneider; Marrit Meier; Berna Beverloo; Rob Pieters
D-HPLC analysis of the entire FLT3 gene in MLL rearranged and hyperdiploid acute lymphoblastic leukemia.
Haematologica 2007;92(11):1565-8.
2007: Andrica C H De Vries; Ronald W Stam; Pauline Schneider; Charlotte M Niemeyer; Elisabeth R van Wering; Oskar A Haas; Christian P Kratz; Monique L den Boer; Rob Pieters; Marry M van den Heuvel-Eibrink
Role of mutation independent constitutive activation of FLT3 in juvenile myelomonocytic leukemia.
Haematologica 2007;92(11):1557-60.
2007: Annelies Hartman; Cor van den Bos; N van Dartel; Theo Stijnen; Rob Pieters
No adverse effect of vincristine on handwriting in children after completion of therapy.
Pediatric blood & cancer 2007;49(6):841-5.
2007: Ronald W Stam; Pauline Schneider; Paola de Lorenzo; Maria Grazia Valsecchi; Monique L den Boer; Rob Pieters
Prognostic significance of high-level FLT3 expression in MLL-rearranged infant acute lymphoblastic leukemia.
Blood 2007;110(7):2774-5.
2007: Robert D van Beek; Marry M van den Heuvel-Eibrink; Joop S E Laven; Frank de Jong; Axel P N Themmen; Friederike G A J Hakvoort-Cammel; Cor van den Bos; Henk van den Berg; Rob Pieters; Sabine M P F de Muinck Keizer-Schrama
Anti-Mullerian hormone is a sensitive serum marker for gonadal function in women treated for Hodgkin's lymphoma during childhood.
The Journal of clinical endocrinology and metabolism 2007;92(10):3869-74.
2007: Jennifer O'Neil; Jonathan Grim; Peter Strack; Sudhir Rao; Deanne Tibbitts; Christopher Winter; James Hardwick; Markus Welcker; Jules P P Meijerink; Rob Pieters; Giulio F Draetta; Rosalie C Pelz; Bruce E Clurman; A Thomas Look
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
The Journal of experimental medicine 2007;204(8):1813-24.
2007: Barbara A E de Koning; Sophie R D Van Der Schoor; Darcos L Wattimena; Peter C de Laat; Rob Pieters; Johannes B Van Goudoever
Chemotherapy does not influence intestinal amino acid uptake in children.
Pediatric research 2007;62(2):195-9.
2007: Barbara A E de Koning; Dicky J Lindenbergh-Kortleve; Rob Pieters; Hans A Büller; Ingrid B Renes; Alexandra Einerhand
Alterations in epithelial and mesenchymal intestinal gene expression during doxorubicin-induced mucositis in mice.
Digestive diseases and sciences 2007;52(8):1814-25.
2007: Rob Pieters; Martin Schrappe; Paola de Lorenzo; Ian Hann; Giulio De Rossi; Maria Felice; Liisa Hovi; Thierry Leblanc; Tomasz Szczepanski; Alina Ferster; Gritta Janka; Jeffrey E Rubnitz; Lewis Silverman; Jan Stary; Myriam Campbell; Chi kong Li; Georg Mann; Ram Suppiah; Andrea Biondi; Ajay Vora; Maria Grazia Valsecchi
A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial.
Lancet 2007;370(9583):240-50.
2007: Monique L den Boer; Rob Pieters
Microarray-based identification of new targets for specific therapies in pediatric leukemia.
Current drug targets 2007;8(6):761-4.
2007: Judith M de Bont; Monique L den Boer; Johan M Kros; Monique Passier; Roel E Reddingius; Peter A E Sillevis Smitt; Theo M Luider; Rob Pieters
Identification of novel biomarkers in pediatric primitive neuroectodermal tumors and ependymomas by proteome-wide analysis.
Journal of neuropathology and experimental neurology 2007;66(6):505-16.
2007: Idoya Lahortiga; Kim De Keersmaecker; Pieter Van Vlierberghe; Carlos Graux; Barbara Cauwelier; Frederic Lambert; Nicole Mentens; Berna Beverloo; Rob Pieters; Frank Speleman; María D Odero; Marijke Bauters; Guy Froyen; Peter Marynen; Peter Vandenberghe; Iwona Wlodarska; Jules P P Meijerink; Jan Cools
Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.
Nature genetics 2007;39(5):593-5.
2007: Wim J E Tissing; Monique L den Boer; Jules P P Meijerink; Renee X Menezes; Sigrid Swagemakers; Peter van der Spek; Stephen E Sallan; Scott A Armstrong; Rob Pieters
Genomewide identification of prednisolone-responsive genes in acute lymphoblastic leukemia cells.
Blood 2007;109(9):3929-35.
2007: M H Maas; Karlien Cransberg; Martine van Grotel; Rob Pieters; Marry M van den Heuvel-Eibrink
Renin-induced hypertension in Wilms tumor patients.
Pediatric blood & cancer 2007;48(5):500-3.
2007: Barbara A E de Koning; Bertine Philipsen-Geerling; Maarten Hoijer; Karel Hählen; Hans A Büller; Rob Pieters
Protection against chemotherapy induced mucositis by TGF-beta(2) in childhood cancer patients: results from a randomized cross-over study.
Pediatric blood & cancer 2007;48(5):532-9.
2007: M W J C Jansen; L Corral; V H J van der Velden; R Panzer-Grümayer; Martin Schrappe; André Schrauder; Rolf Marschalek; Claus Meyer; Monique L den Boer; W J C Hop; Maria Grazia Valsecchi; G Basso; A Biondi; Rob Pieters; Jacques J M van Dongen
Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement.
Leukemia 2007;21(4):633-41.
2007: L Huang; Maarten H Lequin; Rob Pieters; Marry M van den Heuvel-Eibrink
The clinical value of follow-up examinations in childhood T-cell acute lymphoblastic leukemia and T-cell non-Hodgkin's lymphoma.
Pediatric blood & cancer 2007;48(4):468-72.
2007: Barbara A E de Koning; Maria van der Sluis; Dicky J Lindenbergh-Kortleve; Anna Velcich; Rob Pieters; Hans A Büller; Alexandra Einerhand; Ingrid B Renes
Methotrexate-induced mucositis in mucin 2-deficient mice.
Journal of cellular physiology 2007;210(1):144-52.
2006: Pieter Van Vlierberghe; Martine van Grotel; Berna Beverloo; Charles Lee; Tryggvi Helgason; Jessica Buijs-Gladdines; Monique Passier; Elisabeth R van Wering; Anjo J P Veerman; Willem A Kamps; Jules P P Meijerink; Rob Pieters
The cryptic chromosomal deletion del(11)(p12p13) as a new activation mechanism of LMO2 in pediatric T-cell acute lymphoblastic leukemia.
Blood 2006;108(10):3520-9.
2006: Guo Wei; David Twomey; Justin Lamb; Krysta D Schlis; Jyoti Agarwal; Ronald W Stam; Joseph T Opferman; Stephen E Sallan; Monique L den Boer; Rob Pieters; Todd R Golub; Scott A Armstrong
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance.
Cancer cell 2006;10(4):331-42.
2006: Amy Holleman; Monique L den Boer; Meyling H Cheok; Karin M Kazemier; Deqing Pei; James R Downing; Gritta E Janka-Schaub; Ulrich Göbel; Ulrike B Graubner; Ching-Hon Pui; William Evans; Rob Pieters
Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols.
Blood 2006;108(6):1984-90.
2006: Martine van Grotel; Jules P P Meijerink; Berna Beverloo; Anton Langerak; Jessica G C A M Buys-Gladdines; Pauline Schneider; Tim S Poulsen; Monique L den Boer; Martin Horstmann; Willem A Kamps; Anjo J P Veerman; Elisabeth R van Wering; Max M van Noesel; Rob Pieters
The outcome of molecular-cytogenetic subgroups in pediatric T-cell acute lymphoblastic leukemia: a retrospective study of patients treated according to DCOG or COALL protocols.
Haematologica 2006;91(9):1212-21.
2006: Martine van Grotel; King H Lam; Rogier de Man; Auke Beishuizen; Rob Pieters; Marry M van den Heuvel-Eibrink
High relapse rate in children with non-advanced nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL or nodular paragranuloma) treated with chemotherapy only.
Leukemia & lymphoma 2006;47(8):1504-10.
2006: M Meier; Monique L den Boer; Jules P P Meijerink; M J C Broekhuis; Monique Passier; Elisabeth R van Wering; Gritta E Janka-Schaub; Rob Pieters
Differential expression of p73 isoforms in relation to drug resistance in childhood T-lineage acute lymphoblastic leukaemia.
Leukemia 2006;20(8):1377-84.
2006: Judith M de Bont; Monique L den Boer; Roel E Reddingius; Jaap Jansen; Monique Passier; Ron van Schaik; Johan M Kros; Peter A E Sillevis Smitt; Theo H Luider; Rob Pieters
Identification of apolipoprotein A-II in cerebrospinal fluid of pediatric brain tumor patients by protein expression profiling.
Clinical chemistry 2006;52(8):1501-9.
2006: Anne von Bergh; Ellen van Drunen; Elisabeth R van Wering; Laura J C M van Zutven; Ina Hainmann; Gudmar Lönnerholm; Jules P P Meijerink; Rob Pieters; Berna Beverloo
High incidence of t(7;12)(q36;p13) in infant AML but not in infant ALL, with a dismal outcome and ectopic expression of HLXB9.
Genes, chromosomes & cancer 2006;45(8):731-9.
2006: Wim J E Tissing; Jules P P Meijerink; Bas Brinkhof; Mathilde J C Broekhuis; Renee X Menezes; Monique L den Boer; Rob Pieters
Glucocorticoid-induced glucocorticoid-receptor expression and promoter usage is not linked to glucocorticoid resistance in childhood ALL.
Blood 2006;108(3):1045-9.
2006: Pieter Van Vlierberghe; Jules P P Meijerink; C Lee; Adolfo Ferrando; A T Look; Elisabeth R van Wering; Berna Beverloo; J C Aster; Rob Pieters
A new recurrent 9q34 duplication in pediatric T-cell acute lymphoblastic leukemia.
Leukemia 2006;20(7):1245-53.
2006: Jan Hendrik Hooijberg; N A de Vries; G J L Kaspers; Rob Pieters; Gerrit Jansen; Godefridus J Peters
Multidrug resistance proteins and folate supplementation: therapeutic implications for antifolates and other classes of drugs in cancer treatment.
Cancer chemotherapy and pharmacology 2006;58(1):1-12.
2006: Christian M Zwaan; Monique L den Boer; Karin M Kazemier; Karel Hählen; Anne H Loonen; Dirk Reinhardt; Ursula Creutzig; G J L Kaspers; Rob Pieters
Does modulation of P-glycoprotein have clinical relevance in pediatric acute myeloid leukemia?
Blood 2006;107(12):4975-6; author reply 4976-7.
2006: Barbara A E de Koning; Jolanda M van Dieren; Dicky J Lindenbergh-Kortleve; Maria van der Sluis; Tetsuya Matsumoto; Keizo Yamaguchi; Alexandra Einerhand; Janneke N Samsom; Rob Pieters; Edward E S Nieuwenhuis
Contributions of mucosal immune cells to methotrexate-induced mucositis.
International immunology 2006;18(6):941-9.
2006: Inge M Appel; Monique L den Boer; Jules P P Meijerink; Anjo J P Veerman; Nathalie C M Reniers; Rob Pieters
Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia.
Blood 2006;107(11):4244-9.
2006: Barbara A E de Koning; Dicky J Lindenbergh-Kortleve; Rob Pieters; Edmond H H M Rings; Hans A Büller; Ingrid B Renes; Alexandra Einerhand
The effect of cytostatic drug treatment on intestine-specific transcription factors Cdx2, GATA-4 and HNF-1alpha in mice.
Cancer chemotherapy and pharmacology 2006;57(6):801-10.
2006: V H J van der Velden; Patricia G Hoogeveen; Rob Pieters; Jacques J M van Dongen
Impact of two independent bone marrow samples on minimal residual disease monitoring in childhood acute lymphoblastic leukaemia.
British journal of haematology 2006;133(4):382-8.
2006: J Neudenberger; Marc Hotfilder; Annegret Rosemann; Claudia Langebrake; Dirk Reinhardt; Rob Pieters; André Schrauder; Martin Schrappe; Silja Röttgers; Jochen Harbott; Josef Vormoor
Lack of expression of the chondroitin sulphate proteoglycan neuron-glial antigen 2 on candidate stem cell populations in paediatric acute myeloid leukaemia/abn(11q23) and acute lymphoblastic leukaemia/t(4;11).
British journal of haematology 2006;133(3):337-44.
2006: Robert D van Beek; D D L Bezemer; Jules P P Meijerink; Sabine M P F de Muinck Keizer-Schrama; O A Haas; L Te Winkel; Rob Pieters; Marry M van den Heuvel-Eibrink
Repeats in the kringle IV encoding domains in the Apo(a) gene and serum lipoprotein(a) level do not contribute to the risk for avascular necrosis of the bone (AVN) in pediatric acute lymphoblastic leukemia.
Leukemia 2006;20(5):879-80.
2006: Annelies Hartman; Cor van den Bos; Theo Stijnen; Rob Pieters
Decrease in motor performance in children with cancer is independent of the cumulative dose of vincristine.
Cancer 2006;106(6):1395-401.
2006: Inge M Appel; Wim C J Hop; Rob Pieters
Changes in hypercoagulability by asparaginase: a randomized study between two asparaginases.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2006;17(2):139-46.
2006: Ronald W Stam; Monique L den Boer; Rob Pieters
Towards targeted therapy for infant acute lymphoblastic leukaemia.
British journal of haematology 2006;132(5):539-51.
2006: Wendy A G Stams; Berna Beverloo; Monique L den Boer; Renée X de Menezes; R L Stigter; Ellen van Drunen; NL Ramakers-van Woerden; Anne H Loonen; Elisabeth R van Wering; Gritta E Janka-Schaub; Rob Pieters
Incidence of additional genetic changes in the TEL and AML1 genes in DCOG and COALL-treated t(12;21)-positive pediatric ALL, and their relation with drug sensitivity and clinical outcome.
Leukemia 2006;20(3):410-6.
2006: Ronald W Stam; Monique L den Boer; Monique Passier; Gritta E Janka-Schaub; Stephen E Sallan; Scott A Armstrong; Rob Pieters
Silencing of the tumor suppressor gene FHIT is highly characteristic for MLL gene rearranged infant acute lymphoblastic leukemia.
Leukemia 2006;20(2):264-71.
2006: Amy Holleman; Monique L den Boer; Renée X de Menezes; Meyling H Cheok; Cheng Cheng; Karin M Kazemier; Gritta E Janka-Schaub; Ulrich Göbel; Ulrike B Graubner; William Evans; Rob Pieters
The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia.
Blood 2006;107(2):769-76.
2006: Isabelle Hubeek; Godefridus J Peters; Richard Broekhuizen; Christian M Zwaan; Patricia Kaaijk; Elisabeth S van Wering; Brenda E S Gibson; Ursula Creutzig; Gritta E Janka-Schaub; Monique L den Boer; Rob Pieters; G J L Kaspers
In vitro sensitivity and cross-resistance to deoxynucleoside analogs in childhood acute leukemia.
Haematologica 2006;91(1):17-23.
2006: Ronald W Stam; Isabelle Hubeek; Monique L den Boer; J G C A M Buijs-Gladdines; Ursula Creutzig; G J L Kaspers; Rob Pieters
MLL gene rearrangements have no direct impact on Ara-C sensitivity in infant acute lymphoblastic leukemia and childhood M4/M5 acute myeloid leukemia.
Leukemia 2006;20(1):179-82.
2006: Robert D van Beek; Sabine M P F de Muinck Keizer-Schrama; Friederike G A J Hakvoort-Cammel; Inge M van der Sluis; Eric P Krenning; Rob Pieters; Marry M van den Heuvel-Eibrink
No difference between prednisolone and dexamethasone treatment in bone mineral density and growth in long term survivors of childhood acute lymphoblastic leukemia.
Pediatric blood & cancer 2006;46(1):88-93.
2005: Pieter Van Vlierberghe; Jules P P Meijerink; Ronald W Stam; Wendy van der Smissen; Elisabeth R van Wering; Berna Beverloo; Rob Pieters
Activating FLT3 mutations in CD4+/CD8- pediatric T-cell acute lymphoblastic leukemias.
Blood 2005;106(13):4414-5.
2005: Isabelle Hubeek; Ronald W Stam; Godefridus J Peters; Richard Broekhuizen; Jules P P Meijerink; Elisabeth R van Wering; Brenda E S Gibson; Ursula Creutzig; Christian M Zwaan; Jacqueline Cloos; Dirk J Kuik; Rob Pieters; G J L Kaspers
The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia.
British journal of cancer 2005;93(12):1388-94.
2005: Wendy A G Stams; Monique L den Boer; Berna Beverloo; Karin M Kazemier; Elisabeth R van Wering; Gritta E Janka-Schaub; Rob Pieters
Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.
Haematologica 2005;90(12):1697-9.
2005: M Meier; Monique L den Boer; Andrew G Hall; Julie A E Irving; Monique Passier; Lynne Minto; Elisabeth R van Wering; Gritta E Janka-Schaub; Rob Pieters
Relation between genetic variants of the ataxia telangiectasia-mutated (ATM) gene, drug resistance, clinical outcome and predisposition to childhood T-lineage acute lymphoblastic leukaemia.
Leukemia 2005;19(11):1887-95.
2005: Ronald W Stam; Monique L den Boer; Pauline Schneider; Peter Nollau; Martin Horstmann; Berna Beverloo; Ella van der Voort; Maria Grazia Valsecchi; Paola de Lorenzo; Stephen E Sallan; Scott A Armstrong; Rob Pieters
Targeting FLT3 in primary MLL-gene-rearranged infant acute lymphoblastic leukemia.
Blood 2005;106(7):2484-90.
2005: Wim J E Tissing; Melchior Lauten; Jules P P Meijerink; Monique L den Boer; Jan W Koper; Pieter Sonneveld; Rob Pieters
Expression of the glucocorticoid receptor and its isoforms in relation to glucocorticoid resistance in childhood acute lymphocytic leukemia.
Haematologica 2005;90(9):1279-81.
2005: Astrid M Vrakking; Agnes van der Heide; W F M Arts; Rob Pieters; Edwin van der Voort; Judith A C Rietjens; Bregje D Onwuteaka-Philipsen; Paul J van der Maas; Gerrit van der Wal
Medical end-of-life decisions for children in the Netherlands.
Archives of pediatrics & adolescent medicine 2005;159(9):802-9.
2005: Saskia Buitendijk; Cees P van de Ven; Ton G Dumans; Jan C den Hollander; Peter J C M Nowak; Wim J E Tissing; Rob Pieters; Marry M van den Heuvel-Eibrink
Pediatric aggressive fibromatosis: a retrospective analysis of 13 patients and review of literature.
Cancer 2005;104(5):1090-9.
2005: Amy Holleman; Monique L den Boer; Karin M Kazemier; Berna Beverloo; Anne von Bergh; Gritta E Janka-Schaub; Rob Pieters
Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia.
Blood 2005;106(5):1817-23.
2005: Wim J E Tissing; Jules P P Meijerink; Monique L den Boer; Bas Brinkhof; Elisabeth F C van Rossum; Elisabeth R van Wering; Jan W Koper; Pieter Sonneveld; Rob Pieters
Genetic variations in the glucocorticoid receptor gene are not related to glucocorticoid resistance in childhood acute lymphoblastic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(16):6050-6.
2005: Robert de Jonge; Jan Hendrik Hooijberg; Bertrand D van Zelst; Gerrit Jansen; Gerritz Jansen; Christina H van Zantwijk; Christine H van Zantwijk; G J L Kaspers; Gert Jan L Kaspers; Godefridus J Peters; Frits G J Peters; Yaddanapudi Ravindranath; Rob Pieters; Jan Lindemans
Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia.
Blood 2005;106(2):717-20.
2005: L J C M van Zutven; Ellen van Drunen; J M de Bont; M M Wattel; Monique L den Boer; Rob Pieters; Anne Hagemeijer; Rosalyn M Slater; Berna Beverloo
CDKN2 deletions have no prognostic value in childhood precursor-B acute lymphoblastic leukaemia.
Leukemia 2005;19(7):1281-4.
2005: G J L Kaspers; Jelle J M Wijnands; Reinhard Hartmann; Loekie Huismans; Anne H Loonen; Arend Stackelberg; Günter Henze; Rob Pieters; Karel Hählen; Elisabeth R van Wering; Anjo J P Veerman
Immunophenotypic cell lineage and in vitro cellular drug resistance in childhood relapsed acute lymphoblastic leukaemia.
European journal of cancer (Oxford, England : 1990) 2005;41(9):1300-3.
2005: Wendy A G Stams; Monique L den Boer; Amy Holleman; Inge M Appel; Berna Beverloo; Elisabeth R van Wering; Gritta E Janka-Schaub; William Evans; Rob Pieters
Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia.
Blood 2005;105(11):4223-5.
2005: Jules P P Meijerink; Esther M M Van Lieshout; Berna Beverloo; Ellen van Drunen; E J B M Mensink; Merryn Macville; Rob Pieters
Novel murine B-cell lymphoma/leukemia model to study BCL2-driven oncogenesis.
International journal of cancer. Journal international du cancer 2005;114(6):917-25.
2005: Wim J E Tissing; Jules P P Meijerink; Monique L den Boer; Bas Brinkhof; Rob Pieters
mRNA expression levels of (co)chaperone molecules of the glucocorticoid receptor are not involved in glucocorticoid resistance in pediatric ALL.
Leukemia 2005;19(5):727-33.
2005: Wendy A G Stams; Monique L den Boer; Berna Beverloo; Jules P P Meijerink; Elisabeth R van Wering; Gritta E Janka-Schaub; Rob Pieters
Expression levels of TEL, AML1, and the fusion products TEL-AML1 and AML1-TEL versus drug sensitivity and clinical outcome in t(12;21)-positive pediatric acute lymphoblastic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(8):2974-80.
2005: Sanne Lugthart; Meyling H Cheok; Monique L den Boer; Wenjian Yang; Amy Holleman; Cheng Cheng; Ching-Hon Pui; Mary Relling; Gritta E Janka-Schaub; Rob Pieters; William Evans
Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia.
Cancer cell 2005;7(4):375-86.
2005: J M de Bont; Bronno van der Holt; Adriaan W Dekker; Anna van der Does-van den Berg; Pieter Sonneveld; Rob Pieters
[Adolescents with acute lymphatic leukaemia achieve significantly better results when treated following Dutch paediatric oncology protocols than with adult protocols].
Nederlands tijdschrift voor geneeskunde 2005;149(8):400-6.
2005: Marc Hotfilder; Silja Röttgers; Annegret Rosemann; André Schrauder; Martin Schrappe; Rob Pieters; Heribert Jürgens; Jochen Harbott; Josef Vormoor
Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive lymphoid-restricted CD34+CD19- cells.
Cancer research 2005;65(4):1442-9.
2005: Wendy A G Stams; Monique L den Boer; Berna Beverloo; Elisabeth R van Wering; Rob Pieters
Upregulation of asparagine synthetase and cell cycle arrest in t(12;21)-positive ALL.
Leukemia 2005;19(2):318-9; author reply 319-21.
2005: Claus Meyer; Bjoern Schneider; Martin Reichel; Sieglinde Angermueller; Sabine Strehl; Susanne Schnittger; Claudia Schoch; M W J C Jansen; Jacques J M van Dongen; Rob Pieters; Oskar A Haas; Theo Dingermann; Thomas Klingebiel; Rolf Marschalek
Diagnostic tool for the identification of MLL rearrangements including unknown partner genes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):449-54.
2005: P C Top; Wim J E Tissing; Jan-Willem Kuiper; Rob Pieters; C H J van Eijck
L-asparaginase-induced severe necrotizing pancreatitis successfully treated with percutaneous drainage.
Pediatric blood & cancer 2005;44(1):95-7.
2004: J M de Bont; B van der Holt; Adriaan W Dekker; Anna van der Does-van den Berg; Pieter Sonneveld; Rob Pieters
Significant difference in outcome for adolescents with acute lymphoblastic leukemia treated on pediatric vs adult protocols in the Netherlands.
Leukemia 2004;18(12):2032-5.
2004: Jan Hendrik Hooijberg; Godefridus J Peters; G J L Kaspers; peter wielinga; Anjo J P Veerman; Rob Pieters; Gerrit Jansen
Online fluorescent method to assess BCRP/ABCG2 activity in suspension cells.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1451-4.
2004: J M de Bont; Rob Pieters
Management of hyperuricemia with rasburicase review.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1431-40.
2004: N J J Neels; Wim J E Tissing; Rob Pieters; J W Oosterhuis; C P van de Ven; A S Devos
Treatment of an infant with a vaginal yolk sac tumour and distant metastases with chemotherapy only.
Pediatric blood & cancer 2004;43(3):296-7.
2004: Amy Holleman; Meyling H Cheok; Monique L den Boer; Wenjian Yang; Anjo J P Veerman; Karin M Kazemier; Deqing Pei; Cheng Cheng; Ching-Hon Pui; Mary Relling; Gritta E Janka-Schaub; Rob Pieters; William Evans
Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment.
The New England journal of medicine 2004;351(6):533-42.
2004: Jan Hendrik Hooijberg; Gerrit Jansen; Yehuda G Assaraf; Ietje Kathmann; Rob Pieters; Adrie C Laan; Anjo J P Veerman; G J L Kaspers; Godefridus J Peters
Folate concentration dependent transport activity of the Multidrug Resistance Protein 1 (ABCC1).
Biochemical pharmacology 2004;67(8):1541-8.
2004: Eric G Haarman; G J L Kaspers; Rob Pieters; M M A Rottier; Anjo J P Veerman
Glucocorticoid receptor alpha, beta and gamma expression vs in vitro glucocorticod resistance in childhood leukemia.
Leukemia 2004;18(3):530-7.
2004: NL Ramakers-van Woerden; Berna Beverloo; Anjo J P Veerman; B M Camitta; Anne H Loonen; Elisabeth R van Wering; Rosalyn M Slater; Jochen Harbott; Monique L den Boer; W D Ludwig; O A Haas; Gritta E Janka-Schaub; Rob Pieters
In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype.
Leukemia 2004;18(3):521-9.
2004: Ronald W Stam; Marry M van den Heuvel-Eibrink; Monique L den Boer; M E G Ebus; Gritta E Janka-Schaub; J D Allen; Rob Pieters
Multidrug resistance genes in infant acute lymphoblastic leukemia: Ara-C is not a substrate for the breast cancer resistance protein.
Leukemia 2004;18(1):78-83.
2003: Amy Holleman; Monique L den Boer; Karin M Kazemier; Gritta E Janka-Schaub; Rob Pieters
Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia.
Blood 2003;102(13):4541-6.
2003: Pieter Sonneveld; Rob Pieters
Immunophenotyping as a guide for targeted therapy.
Best practice & research. Clinical haematology 2003;16(4):629-44.
2003: Inge M Appel; J P V Pinheiro; Monique L den Boer; Claudia Lanvers; N C M Reniers; Joachim Boos; Rob Pieters
Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: a window study at initial diagnosis of childhood ALL.
Leukemia 2003;17(11):2254-6.
2003: Max M van Noesel; Saskia van Bezouw; Paul A Voûte; James G Herman; Rob Pieters; Rogier Versteeg
Clustering of hypermethylated genes in neuroblastoma.
Genes, chromosomes & cancer 2003;38(3):226-33.
2003: Christian M Zwaan; Soheil Meshinchi; Jerald P Radich; Anjo J P Veerman; Dieuwke R Huismans; Leonhard Munske; Martina Podleschny; Karel Hählen; Rob Pieters; Martin Zimmermann; Dirk Reinhardt; Jochen Harbott; Ursula Creutzig; G J L Kaspers; Frank Griesinger
FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance.
Blood 2003;102(7):2387-94.
2003: Monique L den Boer; Dieter Harms; Rob Pieters; Karin M Kazemier; U Gobel; Dieter Körholz; Ulrike B Graubner; R J Haas; Norbert Jorch; Hans J Spaar; G J L Kaspers; Willem A Kamps; Anna van der Does-van den Berg; Elisabeth R van Wering; Anjo J P Veerman; Gritta E Janka-Schaub
Patient stratification based on prednisolone-vincristine-asparaginase resistance profiles in children with acute lymphoblastic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(17):3262-8.
2003: Ping-Pin Zheng; Theo M Luider; Rob Pieters; Cees J J Avezaat; Martin J van den Bent; Peter A E Sillevis Smitt; Johan M Kros
Identification of tumor-related proteins by proteomic analysis of cerebrospinal fluid from patients with primary brain tumors.
Journal of neuropathology and experimental neurology 2003;62(8):855-62.
2003: Max M van Noesel; Rob Pieters; Paul A Voûte; Rogier Versteeg
The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis.
Cancer letters 2003;197(1-2):165-72.
2003: Wendy A G Stams; Monique L den Boer; Berna Beverloo; Jules P P Meijerink; Rolinda L Stigter; Elisabeth R van Wering; Gritta E Janka-Schaub; Rosalyn Slater; Rob Pieters
Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL.
Blood 2003;101(7):2743-7.
2003: Ronald W Stam; Monique L den Boer; Jules P P Meijerink; Marli E G Ebus; Godefridus J Peters; Paul Noordhuis; Gritta E Janka-Schaub; Scott A Armstrong; Stanley J Korsmeyer; Rob Pieters
Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.
Blood 2003;101(4):1270-6.
2003: Scott A Armstrong; Andrew L Kung; Meghann E Mabon; Lewis B Silverman; Ronald W Stam; Monique L den Boer; Rob Pieters; John H Kersey; Stephen E Sallan; Jonathan A Fletcher; Todd R Golub; James D Griffin; Stanley J Korsmeyer
Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.
Cancer cell 2003;3(2):173-83.
2003: Wim J E Tissing; Jules P P Meijerink; Monique L den Boer; Rob Pieters
Molecular determinants of glucocorticoid sensitivity and resistance in acute lymphoblastic leukemia.
Leukemia 2003;17(1):17-25.
2003: Pamela R Kearns; Zofia M A Chrzanowska-Lightowlers; Rob Pieters; Anjo J P Veerman; Andrew G Hall
Mu class glutathione S-transferase mRNA isoform expression in acute lymphoblastic leukaemia.
British journal of haematology 2003;120(1):80-8.
2002: Christian M Zwaan; G J L Kaspers; Rob Pieters; Karel Hählen; Dieuwke R Huismans; Martin Zimmermann; Jochen Harbott; Rosalyn M Slater; Ursula Creutzig; Anjo J P Veerman
Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.
Blood 2002;100(9):3352-60.
2002: Eric G Haarman; G J L Kaspers; Rob Pieters; M M A Rottier; Monique L den Boer; Gritta E Janka-Schaub; Anjo J P Veerman
In vitro glucocorticoid resistance in childhood leukemia correlates with receptor affinity determined at 37 degrees C, but not with affinity determined at room temperature.
Leukemia 2002;16(9):1882-4.
2002: NL Ramakers-van Woerden; Rob Pieters; D Hoelzer; Rosalyn M Slater; Monique L den Boer; Anne H Loonen; Jochen Harbott; Gritta E Janka-Schaub; W-D Ludwig; Gert Ossenkoppele; Elisabeth R van Wering; Anjo J P Veerman
In vitro drug resistance profile of Philadelphia positive acute lymphoblastic leukemia is heterogeneous and related to age: a report of the Dutch and German Leukemia Study Groups.
Medical and pediatric oncology 2002;38(6):379-86.
2002: NL Ramakers-van Woerden; Rob Pieters; Marianne G Rots; Christina H van Zantwijk; Paul Noordhuis; Berna Beverloo; Godefridus J Peters; Elisabeth R van Wering; B M Camitta; Ching-Hon Pui; Mary Relling; William Evans; Anjo J P Veerman
Infants with acute lymphoblastic leukemia: no evidence for high methotrexate resistance.
Leukemia 2002;16(5):949-51.
2002: Marry M van den Heuvel-Eibrink; Erik A C Wiemer; A Prins; Jules P P Meijerink; P J M Vossebeld; Bronno van der Holt; Rob Pieters; Pieter Sonneveld
Increased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML).
Leukemia 2002;16(5):833-9.
2002: Max M van Noesel; Saskia van Bezouw; Gajja S Salomons; Paul A Voûte; Rob Pieters; Stephen B Baylin; James G Herman; Rogier Versteeg
Tumor-specific down-regulation of the tumor necrosis factor-related apoptosis-inducing ligand decoy receptors DcR1 and DcR2 is associated with dense promoter hypermethylation.
Cancer research 2002;62(7):2157-61.
2002: Christian M Zwaan; G J L Kaspers; Rob Pieters; Karel Hählen; Gritta E Janka-Schaub; Christina H van Zantwijk; Dieuwke R Huismans; Esther de Vries; Marianne G Rots; Godefridus J Peters; Gerrit Jansen; Ursula Creutzig; Anjo J P Veerman
Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome.
Blood 2002;99(1):245-51.
2002: Scott A Armstrong; Jane E Staunton; Lewis B Silverman; Rob Pieters; Monique L den Boer; Mark D Minden; Stephen E Sallan; Eric S Lander; Todd R Golub; Stanley J Korsmeyer
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia.
Nature genetics 2002;30(1):41-7.
2001: Kjeld Schmiegelow; Charlotte Nyvold; Jeanette Seyfarth; Rob Pieters; M M A Rottier; N Knabe; lars peter ryder; Hans O Madsen; Arne Svejgaard; G J L Kaspers
Post-induction residual leukemia in childhood acute lymphoblastic leukemia quantified by PCR correlates with in vitro prednisolone resistance.
Leukemia 2001;15(7):1066-71.
2001: Marry M van den Heuvel-Eibrink; Erik A C Wiemer; M J de Boevere; Bronno van der Holt; P J M Vossebeld; Rob Pieters; Pieter Sonneveld
MDR1 gene-related clonal selection and P-glycoprotein function and expression in relapsed or refractory acute myeloid leukemia.
Blood 2001;97(11):3605-11.
2001: Isabelle Hubeek; NL Ramakers-van Woerden; Rob Pieters; Rosalyn Slater; Berna Beverloo; Elisabeth R van Wering; Willem A Kamps; Karel Hählen; Anjo J P Veerman
TEL/AML1 fusion is not a prognostic factor in Dutch childhood acute lymphoblastic leukaemia.
British journal of haematology 2001;113(1):254-5.
2001: Marianne G Rots; Rob Pieters; Gerrit Jansen; G J L Kaspers; Christina H van Zantwijk; Paul Noordhuis; Daphne Voorn; Elisabeth R van Wering; Ursula Creutzig; Anjo J P Veerman; Godefridus J Peters
A possible role for methotrexate in the treatment of childhood acute myeloid leukaemia, in particular for acute monocytic leukaemia.
European journal of cancer (Oxford, England : 1990) 2001;37(4):492-8.
2001: NL Ramakers-van Woerden; Rob Pieters; Rosalyn M Slater; Anne H Loonen; Berna Beverloo; Ellen van Drunen; Mats Heyman; T C Moreno; Marianne G Rots; Elisabeth R van Wering; Willem A Kamps; Gritta E Janka-Schaub; Anjo J P Veerman
In vitro drug resistance and prognostic impact of p16INK4A/P15INK4B deletions in childhood T-cell acute lymphoblastic leukaemia.
British journal of haematology 2001;112(3):680-90.
2001: Marry M van den Heuvel-Eibrink; Erik A C Wiemer; M J de Boevere; Rosalyn M Slater; Elisabeth M E Smit; M M van Noesel; Bronno van der Holt; Martijn Schoester; Rob Pieters; Pieter Sonneveld
MDR1 expression in poor-risk acute myeloid leukemia with partial or complete monosomy 7.
Leukemia 2001;15(3):398-405.
2001: Pamela R Kearns; Rob Pieters; M M A Rottier; Andrew D J Pearson; Andrew G Hall
Raised blast glutathione levels are associated with an increased risk of relapse in childhood acute lymphocytic leukemia.
Blood 2001;97(2):393-8.
2000: Marianne G Rots; James Willey; Gerrit Jansen; Christina H van Zantwijk; Paul Noordhuis; Jeffrey P DeMuth; E Kuiper; Anjo J P Veerman; Rob Pieters; Godefridus J Peters
mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method.
Leukemia 2000;14(12):2166-75.
2000: Christian M Zwaan; G J L Kaspers; Rob Pieters; NL Ramakers-van Woerden; Monique L den Boer; R Wünsche; M M A Rottier; Karel Hählen; Elisabeth R van Wering; Gritta E Janka-Schaub; Ursula Creutzig; Anjo J P Veerman
Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia.
Blood 2000;96(8):2879-86.
2000: Jan Styczynski; Rob Pieters; Dieuwke R Huismans; Gerrit J Schuurhuis; Mariusz Wysocki; Anjo J P Veerman
In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia.
British journal of haematology 2000;110(4):813-8.
2000: Marianne G Rots; Rob Pieters; G J L Kaspers; Anjo J P Veerman; Godefridus J Peters; Gerrit Jansen
Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukaemia.
British journal of haematology 2000;110(4):791-800.
2000: NL Ramakers-van Woerden; Rob Pieters; Anne H Loonen; Isabelle Hubeek; Ellen van Drunen; Berna Beverloo; Rosalyn M Slater; Jochen Harbott; Jeanette Seyfarth; Elisabeth R van Wering; Karel Hählen; Kjeld Schmiegelow; Gritta E Janka-Schaub; Anjo J P Veerman
TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia.
Blood 2000;96(3):1094-9.
2000: Marianne G Rots; Rob Pieters; Godefridus J Peters; Paul Noordhuis; Christina H van Zantwijk; Günter Henze; Gritta E Janka-Schaub; Anjo J P Veerman; Gerrit Jansen
Methotrexate resistance in relapsed childhood acute lymphoblastic leukaemia.
British journal of haematology 2000;109(3):629-34.
2000: Angelika Dübbers; Gudrun Würthwein; Hans-Joachim Müller; Petra Schulze-Westhoff; M Winkelhorst; E Kurzknabe; Claudia Lanvers; Rob Pieters; G J L Kaspers; Ursula Creutzig; J Ritter; Joachim Boos
Asparagine synthetase activity in paediatric acute leukaemias: AML-M5 subtype shows lowest activity.
British journal of haematology 2000;109(2):427-9.
2000: Marry M van den Heuvel-Eibrink; Pieter Sonneveld; Rob Pieters
The prognostic significance of membrane transport-associated multidrug resistance (MDR) proteins in leukemia.
International journal of clinical pharmacology and therapeutics 2000;38(3):94-110.
1999: Monique L den Boer; Rob Pieters; Karin M Kazemier; Gritta E Janka-Schaub; Günter Henze; Anjo J P Veerman
Relationship between the intracellular daunorubicin concentration, expression of major vault protein/lung resistance protein and resistance to anthracyclines in childhood acute lymphoblastic leukemia.
Leukemia 1999;13(12):2023-30.
1999: Marianne G Rots; Rob Pieters; Godefridus J Peters; Christina H van Zantwijk; Robert Mauritz; Paul Noordhuis; James Willey; Karel Hählen; Ursula Creutzig; Gritta E Janka-Schaub; G J L Kaspers; Anjo J P Veerman; Gerrit Jansen
Circumvention of methotrexate resistance in childhood leukemia subtypes by rationally designed antifolates.
Blood 1999;94(9):3121-8.
1999: D Mui; Rob Pieters; Anjo J P Veerman
[Blood platelets in children too few and too large: the giant platelet syndromes].
Nederlands tijdschrift voor geneeskunde 1999;143(38):1918-22.
1999: G J L Kaspers; Christian M Zwaan; Anjo J P Veerman; Marianne G Rots; Rob Pieters; P Bucsky; M Domula; Ulrich Göbel; N Graf; W Havers; Norbert Jorch; K Kabisch; Hans J Spaar; Jörg Ritter; Ursula Creutzig
Cellular drug resistance in acute myeloid leukemia: literature review and preliminary analysis of an ongoing collaborative study.
Klinische Pädiatrie 1999;211(4):239-44.
1999: Monique L den Boer; P Kapaun; Rob Pieters; Karin M Kazemier; Gritta E Janka-Schaub; Anjo J P Veerman
Myeloid antigen co-expression in childhood acute lymphoblastic leukaemia: relationship with in vitro drug resistance.
British journal of haematology 1999;105(4):876-82.
1999: A E Duyn; G J L Kaspers; Rob Pieters; Christina H van Zantwijk; GJ Broekema; Karel Hählen; Anjo J P Veerman
Effects of interleukin 3, interleukin 7, and B-cell growth factor on proliferation and drug resistance in vitro in childhood acute lymphoblastic leukemia.
Annals of hematology 1999;78(4):163-71.
1999: Marianne G Rots; Rob Pieters; Godefridus J Peters; Paul Noordhuis; Christina H van Zantwijk; G J L Kaspers; Karel Hählen; Ursula Creutzig; Anjo J P Veerman; Gerrit Jansen
Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia.
Blood 1999;93(5):1677-83.
1999: Monique L den Boer; Rob Pieters; Karin M Kazemier; Gritta E Janka-Schaub; Günter Henze; Ursula Creutzig; G J L Kaspers; Pamela R Kearns; Andrew G Hall; Andrew D J Pearson; Anjo J P Veerman
Different expression of glutathione S-transferase alpha, mu and pi in childhood acute lymphoblastic and myeloid leukaemia.
British journal of haematology 1999;104(2):321-7.
1999: Henk J Broxterman; Pieter Sonneveld; Rob Pieters; Jan Lankelma; CA Eekman; Anne H Loonen; M Schoester; Gert Ossenkoppele; Bob Löwenberg; HERBERT PINEDO; Gerrit J Schuurhuis
Do P-glycoprotein and major vault protein (MVP/LRP) expression correlate with in vitro daunorubicin resistance in acute myeloid leukemia?
Leukemia 1999;13(2):258-65.
1999: Marianne G Rots; Rob Pieters; G J L Kaspers; Christina H van Zantwijk; Paul Noordhuis; Robert Mauritz; Anjo J P Veerman; Gerrit Jansen; Godefridus J Peters
Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
Blood 1999;93(3):1067-74.
1999: I R Hegge; G J L Kaspers; Marianne G Rots; Gerrit Jansen; Rob Pieters; Anjo J P Veerman
Lack of cross-resistance between prednisolone and methotrexate in childhood acute lymphoblastic leukemia? A preliminary analysis.
Advances in experimental medicine and biology 1999;457():551-5.
1999: G J L Kaspers; Christian M Zwaan; Rob Pieters; Anjo J P Veerman
Cellular drug resistance in childhood acute myeloid leukemia. A mini-review with emphasis on cell culture assays.
Advances in experimental medicine and biology 1999;457():415-21.
1999: Rob Pieters; G J L Kaspers; NL Ramakers-van Woerden; Monique L den Boer; Marianne G Rots; Christian M Zwaan; Eric G Haarman; Anjo J P Veerman
Resistance testing and mechanisms of resistance in childhood leukemia. Studies from Amsterdam.
Advances in experimental medicine and biology 1999;457():391-5.
1999: Eric G Haarman; G J L Kaspers; Rob Pieters; Christina H van Zantwijk; GJ Broekema; Karel Hählen; Anjo J P Veerman
BCL-2 expression in childhood leukemia versus spontaneous apoptosis, drug induced apoptosis, and in vitro drug resistance.
Advances in experimental medicine and biology 1999;457():325-33.
1999: Pamela R Kearns; Rob Pieters; M M A Rottier; Anjo J P Veerman; K Schmiegalow; Andrew D J Pearson; Andrew G Hall
Glutathione in childhood acute leukaemias.
Advances in experimental medicine and biology 1999;457():211-6.
1998: Monique L den Boer; Rob Pieters; Anjo J P Veerman
Mechanisms of cellular anthracycline resistance in childhood acute leukemia.
Leukemia 1998;12(11):1657-70.
1998: Robert Mauritz; M W Bekkenk; Marianne G Rots; Rob Pieters; E Mini; Christina H van Zantwijk; Anjo J P Veerman; Godefridus J Peters; Gerrit Jansen
Ex vivo activity of methotrexate versus novel antifolate inhibitors of dihydrofolate reductase and thymidylate synthase against childhood leukemia cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2399-410.
1998: Rob Pieters; Monique L den Boer; M Durian; G Janka; Kjeld Schmiegelow; G J L Kaspers; Elisabeth R van Wering; Anjo J P Veerman
Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia--implications for treatment of infants.
Leukemia 1998;12(9):1344-8.
1998: G J L Kaspers; Rob Pieters; Christina H van Zantwijk; Elisabeth R van Wering; Anna van der Does-van den Berg; Anjo J P Veerman
Prednisolone resistance in childhood acute lymphoblastic leukemia: vitro-vivo correlations and cross-resistance to other drugs.
Blood 1998;92(1):259-66.
1998: Monique L den Boer; Rob Pieters; Karin M Kazemier; Gritta E Janka-Schaub; Günter Henze; Anjo J P Veerman
The modulating effect of PSC 833, cyclosporin A, verapamil and genistein on in vitro cytotoxicity and intracellular content of daunorubicin in childhood acute lymphoblastic leukemia.
Leukemia 1998;12(6):912-20.
1998: Monique L den Boer; Rob Pieters; Karin M Kazemier; M M A Rottier; Christian M Zwaan; G J L Kaspers; Gritta E Janka-Schaub; Günter Henze; Ursula Creutzig; Rik J Scheper; Anjo J P Veerman
Relationship between major vault protein/lung resistance protein, multidrug resistance-associated protein, P-glycoprotein expression, and drug resistance in childhood leukemia.
Blood 1998;91(6):2092-8.
1997: Marry M van den Heuvel-Eibrink; Bronno van der Holt; P A W te Boekhorst; Rob Pieters; Martijn Schoester; Bob Löwenberg; Pieter Sonneveld
MDR 1 expression is an independent prognostic factor for response and survival in de novo acute myeloid leukaemia.
British journal of haematology 1997;99(1):76-83.
1997: G J L Kaspers; Anjo J P Veerman; Rob Pieters; Christina H van Zantwijk; Lou A Smets; Elisabeth R van Wering; Anna van der Does-van den Berg
In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia.
Blood 1997;90(7):2723-9.
1997: Monique L den Boer; Christian M Zwaan; Rob Pieters; Karin M Kazemier; M M A Rottier; Marcel J Flens; Rik J Scheper; Anjo J P Veerman
Optimal immunocytochemical and flow cytometric detection of P-gp, MRP and LRP in childhood acute lymphoblastic leukemia.
Leukemia 1997;11(7):1078-85.
1997: Rob Pieters; E Klumper; G J L Kaspers; Anjo J P Veerman
Everything you always wanted to know about cellular drug resistance in childhood acute lymphoblastic leukemia.
Critical reviews in oncology/hematology 1997;25(1):11-26.
1996: G J L Kaspers; Anjo J P Veerman; C Popp-Snijders; M Lomecky; Christina H van Zantwijk; L M Swinkels; Elisabeth R van Wering; Rob Pieters
Comparison of the antileukemic activity in vitro of dexamethasone and prednisolone in childhood acute lymphoblastic leukemia.
Medical and pediatric oncology 1996;27(2):114-21.
1996: E Klumper; Gert Ossenkoppele; Rob Pieters; D R Huismans; A H Loonen; A Rottier; G Westra; Anjo J P Veerman
In vitro resistance to cytosine arabinoside, not to daunorubicin, is associated with the risk of relapse in de novo acute myeloid leukaemia.
British journal of haematology 1996;93(4):903-10.
1996: G J L Kaspers; Anjo J P Veerman; Elisabeth R van Wering; B E Van Der Linden-Schrever; Christina H van Zantwijk; Anna van der Does-van den Berg; Rob Pieters
Prognostic significance of peanut agglutinin binding in childhood acute lymphoblastic leukemia.
Leukemia 1996;10(4):675-81.
1995: E Klumper; Rob Pieters; Anjo J P Veerman; D R Huismans; A H Loonen; Karel Hählen; G J L Kaspers; Elisabeth R van Wering; R Hartmann; G Henze
In vitro cellular drug resistance in children with relapsed/refractory acute lymphoblastic leukemia.
Blood 1995;86(10):3861-8.
1995: G J L Kaspers; Rob Pieters; Christina H van Zantwijk; Elisabeth R van Wering; Anjo J P Veerman
Clinical and cell biological features related to cellular drug resistance of childhood acute lymphoblastic leukemia cells.
Leukemia & lymphoma 1995;19(5-6):407-16.
1995: E Klumper; Rob Pieters; G J L Kaspers; D R Huismans; A H Loonen; M M A Rottier; Elisabeth R van Wering; Anna van der Does-van den Berg; Karel Hählen; Ursula Creutzig
In vitro chemosensitivity assessed with the MTT assay in childhood acute non-lymphoblastic leukemia.
Leukemia 1995;9(11):1864-9.
1995: E Klumper; G Giaccone; Rob Pieters; G Broekema; J van Ark-Otte; Elisabeth R van Wering; G J L Kaspers; Anjo J P Veerman
Topoisomerase II alpha gene expression in childhood acute lymphoblastic leukemia.
Leukemia 1995;9(10):1653-60.
1995: E Klumper; Rob Pieters; M L den Boer; D R Huismans; A H Loonen; Anjo J P Veerman
In vitro anthracycline cross-resistance pattern in childhood acute lymphoblastic leukaemia.
British journal of cancer 1995;71(6):1188-93.
1995: G J L Kaspers; Anjo J P Veerman; Rob Pieters; I Van Zantwijk; Karel Hählen; Elisabeth R van Wering
Drug combination testing in acute lymphoblastic leukemia using the MTT assay.
Leukemia research 1995;19(3):175-81.
1995: G J L Kaspers; Lou A Smets; Rob Pieters; Christina H van Zantwijk; Elisabeth R van Wering; Anjo J P Veerman
Favorable prognosis of hyperdiploid common acute lymphoblastic leukemia may be explained by sensitivity to antimetabolites and other drugs: results of an in vitro study.
Blood 1995;85(3):751-6.
1995: Gerrit J Schuurhuis; Henk J Broxterman; Gert Ossenkoppele; Jan P A Baak; CA Eekman; CM Kuiper; Nicole Feller; T H van Heijningen; E Klumper; Rob Pieters
Functional multidrug resistance phenotype associated with combined overexpression of Pgp/MDR1 and MRP together with 1-beta-D-arabinofuranosylcytosine sensitivity may predict clinical response in acute myeloid leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(1):81-93.
1994: G J L Kaspers; Anjo J P Veerman; Rob Pieters; G J Broekema; D R Huismans; Karin M Kazemier; A H Loonen; M A Rottier; Christina H van Zantwijk; Karel Hählen
Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay.
British journal of cancer 1994;70(6):1047-52.
1994: G J L Kaspers; G Kardos; Rob Pieters; Christina H van Zantwijk; E Klumper; Karel Hählen; F C de Waal; Elisabeth R van Wering; Anjo J P Veerman
Different cellular drug resistance profiles in childhood lymphoblastic and non-lymphoblastic leukemia: a preliminary report.
Leukemia 1994;8(7):1224-9.
1994: Rob Pieters; G J L Kaspers; E Klumper; Elisabeth R van Wering; Anna van der Does-van den Berg; Anjo J P Veerman
[Clinical relevance of resistance against cytostatic agents in children with leukemia].
Nederlands tijdschrift voor geneeskunde 1994;138(14):706-12.
1994: G J L Kaspers; Rob Pieters; E Klumper; F C De Waal; Anjo J P Veerman
Glucocorticoid resistance in childhood leukemia.
Leukemia & lymphoma 1994;13(3-4):187-201.
1994: G L Kaspers; Anjo J P Veerman; Rob Pieters; I van Zantwijk; E Klumper; Karel Hählen; F C de Waal; Elisabeth R van Wering
In vitro cytotoxicity of mitoxantrone, daunorubicin and doxorubicin in untreated childhood acute leukemia.
Leukemia 1994;8(1):24-9.
1994: Rob Pieters; G J L Kaspers; E Klumper; Anjo J P Veerman
Clinical relevance of in vitro drug resistance testing in childhood acute lymphoblastic leukemia: the state of the art.
Medical and pediatric oncology 1994;22(5):299-308.
1994: Anjo J P Veerman; G J L Kaspers; Rob Pieters
Cellular drug resistance in childhood leukemia.
Annals of hematology 1994;69 Suppl 1():S31-4.
1994: D C van Oostveen; Rob Pieters; Godefridus J Peters; Anjo J P Veerman
Purine nucleotide interconversion enzymes in childhood leukemia: relation with cell cycle and clinical outcome.
Advances in experimental medicine and biology 1994;370():209-12.
1993: Rob Pieters; G J L Kaspers; Elisabeth R van Wering; D R Huismans; A H Loonen; Karel Hählen; Anjo J P Veerman
Cellular drug resistance profiles that might explain the prognostic value of immunophenotype and age in childhood acute lymphoblastic leukemia.
Leukemia 1993;7(3):392-7.
1993: G J L Kaspers; Rob Pieters; E Klumper; F C de Waal; Anjo J P Veerman
[The treatment of recurrence in children with acute lymphatic leukemia. Current results and various developments].
Tijdschrift voor kindergeneeskunde 1993;61(1):1-7.
1993: Rob Pieters; G J L Kaspers; Elisabeth R van Wering; D R Huismans; A H Loonen; Karel Hählen; Anjo J P Veerman
Cellular drug sensitivity of immunophenotypic subgroups of childhood acute lymphoblastic leukemia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():249-56.
1992: Rob Pieters; D R Huismans; A H Loonen; Godefridus J Peters; Karel Hählen; Anna van der Does-van den Berg; Elisabeth R van Wering; Anjo J P Veerman
Relation of 5'-nucleotidase and phosphatase activities with immunophenotype, drug resistance and clinical prognosis in childhood leukemia.
Leukemia research 1992;16(9):873-80.
1992: Rob Pieters; D R Huismans; A H Loonen; Godefridus J Peters; Karel Hählen; Anna van der Does-van den Berg; Elisabeth R van Wering; Anjo J P Veerman
Hypoxanthine-guanine phosphoribosyl-transferase in childhood leukemia: relation with immunophenotype, in vitro drug resistance and clinical prognosis.
International journal of cancer. Journal international du cancer 1992;51(2):213-7.
1992: Rob Pieters; D R Huismans; A H Loonen; Godefridus J Peters; Karel Hählen; Anna van der Does-van den Berg; Elisabeth R van Wering; Anjo J P Veerman
Adenosine deaminase and purine nucleoside phosphorylase in childhood lymphoblastic leukemia: relation with differentiation stage, in vitro drug resistance and clinical prognosis.
Leukemia 1992;6(5):375-80.
1992: Rob Pieters; T Hongo; A H Loonen; D R Huismans; Henk J Broxterman; Karel Hählen; Anjo J P Veerman
Different types of non-P-glycoprotein mediated multiple drug resistance in children with relapsed acute lymphoblastic leukaemia.
British journal of cancer 1992;65(5):691-7.
1991: E Horst; T Radaszkiewicz; A Hooftman-den Otter; Rob Pieters; J J van Dongen; Chris J L M Meijer; Steven T Pals
Expression of the leucocyte integrin LFA-1 (CD11a/CD18) and its ligand ICAM-1 (CD54) in lymphoid malignancies is related to lineage derivation and stage of differentiation but not to tumor grade.
Leukemia 1991;5(10):848-53.
1991: Rob Pieters; D R Huismans; A H Loonen; Karel Hählen; Anjo J P Veerman
Cytotoxic effects of vitamin A in combination with vincristine, daunorubicin and 6-thioguanine upon cells from lymphoblastic leukemic patients.
Japanese journal of cancer research : Gann 1991;82(9):1051-5.
1991: G J L Kaspers; Rob Pieters; Christina H van Zantwijk; P A De Laat; F C De Waal; Elisabeth R van Wering; Anjo J P Veerman
In vitro drug sensitivity of normal peripheral blood lymphocytes and childhood leukaemic cells from bone marrow and peripheral blood.
British journal of cancer 1991;64(3):469-74.
1991: Rob Pieters; D R Huismans; A H Loonen; Karel Hählen; Anna van der Does-van den Berg; Elisabeth R van Wering; Anjo J P Veerman
Relation of cellular drug resistance to long-term clinical outcome in childhood acute lymphoblastic leukaemia.
Lancet 1991;338(8764):399-403.
1991: Rob Pieters; L F Thompson; G J Broekema; D R Huismans; Godefridus J Peters; Steven T Pals; E Horst; Karel Hählen; Anjo J P Veerman
Expression of 5'-nucleotidase (CD73) related to other differentiation antigens in leukemias of B-cell lineage.
Blood 1991;78(2):488-92.
1990: Rob Pieters; A H Loonen; D R Huismans; G J Broekema; M W Dirven; M W Heyenbrok; Karel Hählen; Anjo J P Veerman
In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions.
Blood 1990;76(11):2327-36.
1990: E Horst; Chris J L M Meijer; T Radaskiewicz; J J van Dongen; Rob Pieters; Carl Figdor; A Hooftman; Steven T Pals
Expression of a human homing receptor (CD44) in lymphoid malignancies and related stages of lymphoid development.
Leukemia 1990;4(5):383-9.
1990: Anjo J P Veerman; Rob Pieters
Drug sensitivity assays in leukaemia and lymphoma.
British journal of haematology 1990;74(4):381-4.
1989: Rob Pieters; A H Taets van Amerongen; A I van Brenk; Anjo J P Veerman
[Bone necrosis as a sequela of chemotherapy in hematologically malignant disorders].
Nederlands tijdschrift voor geneeskunde 1989;133(43):2117-22.
1989: Rob Pieters; A M van der Schans-Dop; A I van Brenk; A H Taets van Amerongen; Anjo J P Veerman
Osteonecrosis following chemotherapy for leukemia.
European journal of haematology 1989;43(3):262-4.
1989: Rob Pieters; D R Huismans; A Leyva; Anjo J P Veerman
Comparison of the rapid automated MTT-assay with a dye exclusion assay for chemosensitivity testing in childhood leukaemia.
British journal of cancer 1989;59(2):217-20.
1989: Rob Pieters; D R Huismans; A Leyva; Anjo J P Veerman
Sensitivity to purine analogues in childhood leukemia assessed by the automated MTT-assay.
Advances in experimental medicine and biology 1989;253A():447-54.
1988: Rob Pieters; Anjo J P Veerman
The role of 5'nucleotidase in therapy-resistance of childhood leukemia.
Medical hypotheses 1988;27(1):77-80.
1988: Rob Pieters; D R Huismans; A Leyva; Anjo J P Veerman
Adaptation of the rapid automated tetrazolium dye based (MTT) assay for chemosensitivity testing in childhood leukemia.
Cancer letters 1988;41(3):323-32.
1988: L J van den Doel; Rob Pieters; D R Huismans; Christina H van Zantwijk; A H Loonen; G J Broekema; F C de Waal; Anjo J P Veerman
Immunological phenotype of lymphoid cells in regenerating bone marrow of children after treatment for acute lymphoblastic leukemia.
European journal of haematology 1988;41(2):170-5.
1988: T E van Zanten; R P Golding; A H Taets van Amerongen; Rob Pieters; Anjo J P Veerman
Nuclear magnetic resonance imaging of bone marrow in childhood leukaemia.
Clinical radiology 1988;39(1):77-81.
1987: Rob Pieters; A I van Brenk; Anjo J P Veerman; A H van Amerongen; T E van Zanten; R P Golding
Bone marrow magnetic resonance studies in childhood leukemia. Evaluation of osteonecrosis.
Cancer 1987;60(12):2994-3000.
1987: Rob Pieters; A I van Brenk; Anjo J P Veerman; A H Taets van Amerongen; T E van Zanten; R P Golding
[Electron spin resonance tomography of the musculoskeletal system].
Nederlands tijdschrift voor geneeskunde 1987;131(36):1586.
1987: Rob Pieters; Anjo J P Veerman
Prognostic significance of acid alpha-naphthyl acetate esterase and acid phosphatase in childhood acute lymphoblastic leukemia.
Leukemia research 1987;11(11):995-9.