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Taina Pihlajaniemi

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Niina Salokorpi; Hannu Tuominen; Sanna K Yrjänä; Taina Pihlajaniemi; Esa Heikkinen; Ritva Heljasvaara; Ari Karttunen; John Koivukangas
Expression of VEGF and collagen XVIII in meningiomas: correlations with histopathological and MRI characteristics.
Aida Field-Ridley; Ian Adatia; Sanjeev Datar; Wen Hui Gong; Ritva Heljasvaara; Roberta L Keller; Peter Oishi; Taina Pihlajaniemi; Christine Sun; Jeffrey R Fineman
Endostatin, an inhibitor of angiogenesis, decreases after bidirectional superior cavopulmonary anastamosis.
Jianmin Su; Kaiwen Su; Karen Gorse; Kurt F Hauser; Taina Pihlajaniemi; Sylvie Ricard-Blum; Renee S Stenbjorn; Michael A Fox
Target-derived matricryptins organize cerebellar synapse formation through α3β1 integrins.

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2013: Niina Salokorpi; Hannu Tuominen; Sanna K Yrjänä; Taina Pihlajaniemi; Esa Heikkinen; Ritva Heljasvaara; Ari Karttunen; John Koivukangas
Expression of VEGF and collagen XVIII in meningiomas: correlations with histopathological and MRI characteristics.
Acta neurochirurgica 2013;155(6):989-96.
2013: Aida Field-Ridley; Ian Adatia; Sanjeev Datar; Wen Hui Gong; Ritva Heljasvaara; Roberta L Keller; Peter Oishi; Taina Pihlajaniemi; Christine Sun; Jeffrey R Fineman
Endostatin, an inhibitor of angiogenesis, decreases after bidirectional superior cavopulmonary anastamosis.
Pediatric cardiology 2013;34(2):291-5.
2012: Jianmin Su; Kaiwen Su; Karen Gorse; Kurt F Hauser; Taina Pihlajaniemi; Sylvie Ricard-Blum; Renee S Stenbjorn; Michael A Fox
Target-derived matricryptins organize cerebellar synapse formation through α3β1 integrins.
Cell reports 2012;2(2):223-30.
2012: Tanja Holopainen; Dennis Jones; Vanessa López-Alpuche; Wang Min; Taina Pihlajaniemi; Denis Tvorogov; Zoltan Wiener; Wei Zheng; Leif C Andersson; Gabriela D'Amico; Yun He; Ritva Heljasvaara; Kari Alitalo
Deletion of the endothelial Bmx tyrosine kinase decreases tumor angiogenesis and growth.
Cancer research 2012;72(14):3512-21.
2012: Anne Heikkinen; Hongmin Tu; Taina Pihlajaniemi
Collagen XIII: a type II transmembrane protein with relevance to musculoskeletal tissues, microvessels and inflammation.
The international journal of biochemistry & cell biology 2012;44(5):714-7.
2012: Mari Aikio; Ilkka Alahuhta; Ritva Heljasvaara; Carlos López-Otín; Sini Nurmenniemi; Riitta Palovuori; Taina Pihlajaniemi; Tuula Salo; Timo Sorsa; Juho Suojanen; Susanna Teppo; Pia Nyberg
Arresten, a collagen-derived angiogenesis inhibitor, suppresses invasion of squamous cell carcinoma.
PloS one 2012;7(12):e51044.
2011: Mehdi Farshchian; Reidar Grénman; Ritva Heljasvaara; Markku Kallajoki; Atte Kivisaari; Juha Peltonen; Taina Pihlajaniemi; Pilvi Riihilä; Risto Ala-Aho; Veli-Matti Kähäri
Serpin peptidase inhibitor clade A member 1 (SerpinA1) is a novel biomarker for progression of cutaneous squamous cell carcinoma.
The American journal of pathology 2011;179(3):1110-9.
2011: Aino I Kinnunen; Raija Sormunen; Harri Elamaa; Lotta Seppinen; R Tyler Miller; Yoshifumi Ninomiya; Paul A Janmey; Taina Pihlajaniemi
Lack of collagen XVIII long isoforms affects kidney podocytes, whereas the short form is needed in the proximal tubular basement membrane.
The Journal of biological chemistry 2011;286(10):7755-64.
2011: Lotta Seppinen; Taina Pihlajaniemi
The multiple functions of collagen XVIII in development and disease.
Matrix biology : journal of the International Society for Matrix Biology 2011;30(2):83-92.
2010: Karolina Rasi; Jarkko Piuhola; Marcus Czabanka; Raija Sormunen; Mika Ilves; Hanna Leskinen; Jaana Rysä; Risto Kerkelä; Paul Janmey; Ritva Heljasvaara; Keijo Peuhkurinen; Olli Vuolteenaho; Heikki Ruskoaho; Peter Vajkoczy; Taina Pihlajaniemi; Lauri Eklund
Collagen XV is necessary for modeling of the extracellular matrix and its deficiency predisposes to cardiomyopathy.
Circulation research 2010;107(10):1241-52.
2010: Jameel Dennis; Daniel T Meehan; Duane C Delimont; Marisa Zallocchi; Greg A Perry; Stacie O'Brien; Hongmin Tu; Taina Pihlajaniemi; Dominic Cosgrove
Collagen XIII induced in vascular endothelium mediates alpha1beta1 integrin-dependent transmigration of monocytes in renal fibrosis.
The American journal of pathology 2010;177(5):2527-40.
2010: Karolina Rasi; Merja Hurskainen; Mika Kallio; Saara Stavén; Raija Sormunen; Anthony M Heape; Robin L Avila; Daniel Kirschner; Anu Muona; Uolevi Tolonen; Heikki Tanila; P Huhtala; Raija Soininen; Taina Pihlajaniemi
Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(43):14490-501.
2010: Anne Latvanlehto; Michael A Fox; Raija Sormunen; Hongmin Tu; Tuomo Oikarainen; Anu Koski; Nikolay Naumenko; Anastasia Shakirzyanova; Mika Kallio; Mika Ilves; Rashid Giniatullin; Joshua R Sanes; Taina Pihlajaniemi
Muscle-derived collagen XIII regulates maturation of the skeletal neuromuscular junction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(37):12230-41.
2010: Merja Hurskainen; Florence Ruggiero; Pasi O Hägg; Taina Pihlajaniemi; P Huhtala
Recombinant human collagen XV regulates cell adhesion and migration.
The Journal of biological chemistry 2010;285(8):5258-65.
2009: Asa Thulin; Maria Ringvall; Anna Dimberg; Karin Kårehed; Timo Väisänen; Marja-Riitta Väisänen; Osama Hamad; Jian Wang; Rolf Bjerkvig; Bo Nilsson; Taina Pihlajaniemi; Helena Akerud; Kristian Pietras; Willi Jahnen-Dechent; Agneta Siegbahn; Anna-Karin Olsson
Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein.
Molecular cancer research : MCR 2009;7(11):1792-802.
2009: Annina Sipola; Lotta Seppinen; Taina Pihlajaniemi; Juha Tuukkanen
Endostatin affects osteoblast behavior in vitro, but collagen XVIII/endostatin is not essential for skeletal development in vivo.
Calcified tissue international 2009;85(5):412-20.
2009: Laura Huilaja; Tiina Hurskainen; Helena Autio-Harmainen; Raija Sormunen; Hongmin Tu; Silke C Hofmann; Taina Pihlajaniemi; Leena Bruckner-Tuderman; Kaisa Tasanen
Glycine substitution mutations cause intracellular accumulation of collagen XVII and affect its post-translational modifications.
The Journal of investigative dermatology 2009;129(9):2302-6.
2009: Oscar Suzuki; Erika Kague; Kelly Bagatini; Hongmin Tu; Ritva Heljasvaara; Lorenza Carvalhaes; Elisandra Gava; Gisele de Oliveira; Paulo Godoi; Glaucius Oliva; Gregory Kitten; Taina Pihlajaniemi; Maria Rita Passos-Bueno
Novel pathogenic mutations and skin biopsy analysis in Knobloch syndrome.
Molecular vision 2009;15():801-9.
2009: Gavin D Perkins; N Nathani; Alex G Richter; Daniel Park; Murali Shyamsundar; Ritva Heljasvaara; Taina Pihlajaniemi; Mav Manji; WS Tunnicliffe; Danny F McAuley; Fang Gao; David R Thickett
Type XVIII collagen degradation products in acute lung injury.
Critical care (London, England) 2009;13(2):R52.
2008: Jenni Tahkola; Juha Räsänen; Malin Sund; Kaarin Mäkikallio; Helena Autio-Harmainen; Taina Pihlajaniemi
Cardiac dysfunction in transgenic mouse fetuses overexpressing shortened type XIII collagen.
Cell and tissue research 2008;333(1):61-9.
2008: Lotta Seppinen; Raija Sormunen; Ylermi Soini; Harri Elamaa; Ritva Heljasvaara; Taina Pihlajaniemi
Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing.
Matrix biology : journal of the International Society for Matrix Biology 2008;27(6):535-46.
2008: Delphine Quélard; Elise Lavergne; Ismaïl Hendaoui; Harri Elamaa; Ulla Tiirola; Ritva Heljasvaara; Taina Pihlajaniemi; Bruno Clément; Orlando Musso
A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling.
PloS one 2008;3(4):e1878.
2007: Gaëlle Brideau; Markus Makinen; Harri Elamaa; Hongmin Tu; Gunnar Nilsson; Kari Alitalo; Taina Pihlajaniemi; Ritva Heljasvaara
Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice.
Cancer research 2007;67(24):11528-35.
2007: Johanna W A M Celie; Niels W P Rutjes; Eelco D Keuning; Raija Soininen; Ritva Heljasvaara; Taina Pihlajaniemi; Angelika M Dräger; Sonja Zweegman; Floortje L Kessler; Robert H J Beelen; Sandrine Florquin; Jan Aten; Jacob Van Den Born
Subendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/reperfusion.
The American journal of pathology 2007;170(6):1865-78.
2007: Anne Snellman; Anne Tuomisto; Anu Koski; Anne Latvanlehto; Taina Pihlajaniemi
The role of disulfide bonds and alpha-helical coiled-coils in the biosynthesis of type XIII collagen and other collagenous transmembrane proteins.
The Journal of biological chemistry 2007;282(20):14898-905.
2007: Noora Vainionpää; Ralf Bützow; Mika Hukkanen; David G Jackson; Taina Pihlajaniemi; Lynn Y Sakai; Ismo Virtanen
Basement membrane protein distribution in LYVE-1-immunoreactive lymphatic vessels of normal tissues and ovarian carcinomas.
Cell and tissue research 2007;328(2):317-28.
2007: Taina Pihlajaniemi
[Not Available].
Duodecim; lääketieteellinen aikakauskirja 2007;123(12):1371-3.
2007: Marko Määttä; Ritva Heljasvaara; Taina Pihlajaniemi; Marita Uusitalo
Collagen XVIII/endostatin shows a ubiquitous distribution in human ocular tissues and endostatin-containing fragments accumulate in ocular fluid samples.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2007;245(1):74-81.
2006: Timo Väisänen; Marja-Riitta Väisänen; Taina Pihlajaniemi
Modulation of the cellular cholesterol level affects shedding of the type XIII collagen ectodomain.
The Journal of biological chemistry 2006;281(44):33352-62.
2006: Marko Määttä; Timo Väisänen; Marja-Riitta Väisänen; Taina Pihlajaniemi; Timo M T Tervo
Altered expression of type XIII collagen in keratoconus and scarred human cornea: Increased expression in scarred cornea is associated with myofibroblast transformation.
Cornea 2006;25(4):448-53.
2006: Marko Määttä; Ritva Heljasvaara; Raija Sormunen; Taina Pihlajaniemi; Helena Autio-Harmainen; Timo M T Tervo
Differential expression of collagen types XVIII/endostatin and XV in normal, keratoconus, and scarred human corneas.
Cornea 2006;25(3):341-9.
2006: Lorenza S Carvalhaes; Othon L Gervásio; Cristina Guatimosim; Ritva Heljasvaara; Raija Sormunen; Taina Pihlajaniemi; Gregory T Kitten
Collagen XVIII/endostatin is associated with the epithelial-mesenchymal transformation in the atrioventricular valves during cardiac development.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(1):132-42.
2006: Marja-Riitta Väisänen; Timo Väisänen; Hongmin Tu; Päivi L Pirilä; Raija Sormunen; Taina Pihlajaniemi
The shed ectodomain of type XIII collagen associates with the fibrillar fibronectin matrix and may interfere with its assembly in vitro.
The Biochemical journal 2006;393(Pt 1):43-50.
2005: Timo Väisänen; Marja-Riitta Väisänen; Helena Autio-Harmainen; Taina Pihlajaniemi
Type XIII collagen expression is induced during malignant transformation in various epithelial and mesenchymal tumours.
The Journal of pathology 2005;207(3):324-35.
2005: Marko Määttä; Ralf Bützow; Jani Luostarinen; Noora Petäjäniemi; Taina Pihlajaniemi; Sirpa Salo; Kaoru Miyazaki; Helena Autio-Harmainen; Ismo Virtanen
Differential expression of laminin isoforms in ovarian epithelial carcinomas suggesting different origin and providing tools for differential diagnosis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(10):1293-300.
2005: Merja Hurskainen; Lauri Eklund; Pasi O Hägg; Marcus Fruttiger; Raija Sormunen; Mika Ilves; Taina Pihlajaniemi
Abnormal maturation of the retinal vasculature in type XVIII collagen/endostatin deficient mice and changes in retinal glial cells due to lack of collagen types XV and XVIII.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(11):1564-6.
2005: Riikka Ylönen; Tuomo Kyrönlahti; Malin Sund; Mika Ilves; Petri Lehenkari; Juha Tuukkanen; Taina Pihlajaniemi
Type XIII collagen strongly affects bone formation in transgenic mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(8):1381-93.
2005: Ritva Heljasvaara; Pia Nyberg; Jani Luostarinen; Mataleena Parikka; Pia Heikkilä; Marko Rehn; Timo Sorsa; Tuula Salo; Taina Pihlajaniemi
Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases.
Experimental cell research 2005;307(2):292-304.
2005: Harri Elamaa; Raija Sormunen; Marko Rehn; Raija Soininen; Taina Pihlajaniemi
Endostatin overexpression specifically in the lens and skin leads to cataract and ultrastructural alterations in basement membranes.
The American journal of pathology 2005;166(1):221-9.
2004: Aino Utriainen; Raija Sormunen; Mikko I Kettunen; Lorenza S Carvalhaes; Esko Sajanti; Lauri Eklund; Risto A Kauppinen; Gregory T Kitten; Taina Pihlajaniemi
Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line.
Human molecular genetics 2004;13(18):2089-99.
2004: Marja-Riitta Väisänen; Timo Väisänen; Taina Pihlajaniemi
The shed ectodomain of type XIII collagen affects cell behaviour in a matrix-dependent manner.
The Biochemical journal 2004;380(Pt 3):685-93.
2004: Anu Väänänen; Leo Tjäderhane; Lauri Eklund; Ritva Heljasvaara; Taina Pihlajaniemi; Riitta Herva; Yanli Ding; John D Bartlett; Tuula Salo
Expression of collagen XVIII and MMP-20 in developing teeth and odontogenic tumors.
Matrix biology : journal of the International Society for Matrix Biology 2004;23(3):153-61.
2003: Ritva Ylikärppä; Lauri Eklund; Raija Sormunen; Antti I Kontiola; Aino Utriainen; Marko Määttä; Naomi Fukai; Bjorn R Olsen; Taina Pihlajaniemi
Lack of type XVIII collagen results in anterior ocular defects.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(15):2257-9.
2003: Anne Latvanlehto; Anne Snellman; Hongmin Tu; Taina Pihlajaniemi
Type XIII collagen and some other transmembrane collagens contain two separate coiled-coil motifs, which may function as independent oligomerization domains.
The Journal of biological chemistry 2003;278(39):37590-9.
2003: Ritva Ylikärppä; Lauri Eklund; Raija Sormunen; Anu Muona; Naomi Fukai; Bjorn R Olsen; Taina Pihlajaniemi
Double knockout mice reveal a lack of major functional compensation between collagens XV and XVIII.
Matrix biology : journal of the International Society for Matrix Biology 2003;22(5):443-8.
2003: Harri Elamaa; Anne Snellman; Marko Rehn; Helena Autio-Harmainen; Taina Pihlajaniemi
Characterization of the human type XVIII collagen gene and proteolytic processing and tissue location of the variant containing a frizzled motif.
Matrix biology : journal of the International Society for Matrix Biology 2003;22(5):427-42.
2003: Pia Nyberg; Pia Heikkilä; Timo Sorsa; Jani Luostarinen; Ritva Heljasvaara; Ulf-Hakan Stenman; Taina Pihlajaniemi; Tuula Salo
Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13.
The Journal of biological chemistry 2003;278(25):22404-11.
2003: Seppo Vainio; Yanfeng Lin; Taina Pihlajaniemi
Induced repatterning of type XVIII collagen associates with ectopic Sonic hedgehog and lung surfactant C gene expression and changes in epithelial epigenesis in the ureteric bud.
Journal of the American Society of Nephrology : JASN 2003;14 Suppl 1():S3-8.
2003: Hiroto Kawashima; Norifumi Watanabe; Mayumi Hirose; Xin Sun; Kazuyuki Atarashi; Tetsuya Kimura; Kenichi Shikata; Mitsuhiro Matsuda; Daisuke Ogawa; Ritva Heljasvaara; Marko Rehn; Taina Pihlajaniemi; Masayuki Miyasaka
Collagen XVIII, a basement membrane heparan sulfate proteoglycan, interacts with L-selectin and monocyte chemoattractant protein-1.
The Journal of biological chemistry 2003;278(15):13069-76.
2003: Yanfeng Lin; Shaobing Zhang; Juha Tuukkanen; Hellevi Peltoketo; Taina Pihlajaniemi; Seppo Vainio
Patterning parameters associated with the branching of the ureteric bud regulated by epithelial-mesenchymal interactions.
The International journal of developmental biology 2003;47(1):3-13.
2003: Reijo J Linnola; Malin Sund; Riikka Ylönen; Taina Pihlajaniemi
Adhesion of soluble fibronectin, vitronectin, and collagen type IV to intraocular lens materials.
Journal of cataract and refractive surgery 2003;29(1):146-52.
2002: Jack van Horssen; Micha M M Wilhelmus; Ritva Heljasvaara; Taina Pihlajaniemi; Pieter Wesseling; Robert M W de Waal; Marcel M Verbeek
Collagen XVIII: a novel heparan sulfate proteoglycan associated with vascular amyloid depositions and senile plaques in Alzheimer's disease brains.
Brain pathology (Zurich, Switzerland) 2002;12(4):456-62.
2002: Hongmin Tu; Takako Sasaki; Anne Snellman; Walter Göhring; Päivi L Pirilä; Rupert Timpl; Taina Pihlajaniemi
The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.
The Journal of biological chemistry 2002;277(25):23092-9.
2002: Harri Elamaa; Josi Peterson; Taina Pihlajaniemi; Olivier Destrée
Cloning of three variants of type XVIII collagen and their expression patterns during Xenopus laevis development.
Mechanisms of development 2002;114(1-2):109-13.
2002: Naomi Fukai; Lauri Eklund; Alexander G Marneros; Suk Paul Oh; Douglas R Keene; Lawrence Tamarkin; Merja Hurskainen; Mika Ilves; En Li; Taina Pihlajaniemi; Bjorn R Olsen
Lack of collagen XVIII/endostatin results in eye abnormalities.
The EMBO journal 2002;21(7):1535-44.
2002: Anu Muona; Lauri Eklund; Timo Väisänen; Taina Pihlajaniemi
Developmentally regulated expression of type XV collagen correlates with abnormalities in Col15a1(-/-) mice.
Matrix biology : journal of the International Society for Matrix Biology 2002;21(1):89-102.
2001: Ari-Pekka Kvist; Anne Latvanlehto; Malin Sund; Lauri Eklund; Timo Väisänen; Pasi O Hägg; Raija Sormunen; Jyrki Komulainen; R Fässler; Taina Pihlajaniemi
Lack of cytosolic and transmembrane domains of type XIII collagen results in progressive myopathy.
The American journal of pathology 2001;159(4):1581-92.
2001: Malin Sund; Riikka Ylönen; Anne Tuomisto; Raija Sormunen; J Tahkola; Ari-Pekka Kvist; Sirpa Kontusaari; Helena Autio-Harmainen; Taina Pihlajaniemi
Abnormal adherence junctions in the heart and reduced angiogenesis in transgenic mice overexpressing mutant type XIII collagen.
The EMBO journal 2001;20(18):5153-64.
2001: Sara A Wickström; Tanja Veikkola; Marko Rehn; Taina Pihlajaniemi; Kari Alitalo; Jorma Keski-Oja
Endostatin-induced modulation of plasminogen activation with concomitant loss of focal adhesions and actin stress fibers in cultured human endothelial cells.
Cancer research 2001;61(17):6511-6.
2001: Malin Sund; Timo Väisänen; S Kaukinen; Mika Ilves; Hongmin Tu; Helena Autio-Harmainen; H Rauvala; Taina Pihlajaniemi
Distinct expression of type XIII collagen in neuronal structures and other tissues during mouse development.
Matrix biology : journal of the International Society for Matrix Biology 2001;20(4):215-31.
2001: Riitta Sallinen; Anne Latvanlehto; Ari-Pekka Kvist; Marko Rehn; I Eerola; M L Chu; Paolo Bonaldo; B Saitta; Giorgio M Bressan; Taina Pihlajaniemi; Eero Vuorio; Aarno Palotie; Maija Wessman; Nina Horelli-Kuitunen
Physical mapping of mouse collagen genes on chromosome 10 by high-resolution FISH.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(5):340-6.
2001: Yanfeng Lin; Shaobing Zhang; Marko Rehn; Petri Itäranta; Juha Tuukkanen; R Heljäsvaara; Hellevi Peltoketo; Taina Pihlajaniemi; Seppo Vainio
Induced repatterning of type XVIII collagen expression in ureter bud from kidney to lung type: association with sonic hedgehog and ectopic surfactant protein C.
Development (Cambridge, England) 2001;128(9):1573-85.
2001: Orlando Musso; Nathalie Theret; Ritva Heljasvaara; Marko Rehn; Bruno Turlin; Jean-Pierre Campion; Taina Pihlajaniemi; Bruno Clement
Tumor hepatocytes and basement membrane-Producing cells specifically express two different forms of the endostatin precursor, collagen XVIII, in human liver cancers.
Hepatology (Baltimore, Md.) 2001;33(4):868-76.
2001: Brian D Ackley; Jennifer R Crew; Harri Elamaa; Taina Pihlajaniemi; C J Kuo; James M Kramer
The NC1/endostatin domain of Caenorhabditis elegans type XVIII collagen affects cell migration and axon guidance.
The Journal of cell biology 2001;152(6):1219-32.
2001: Lauri Eklund; Jarkko Piuhola; Jyrki Komulainen; Raija Sormunen; C Ongvarrasopone; R Fássler; Anu Muona; Mika Ilves; Heikki Ruskoaho; T E S Takala; Taina Pihlajaniemi
Lack of type XV collagen causes a skeletal myopathy and cardiovascular defects in mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1194-9.
2001: Marko Rehn; Tanja Veikkola; E Kukk-Valdre; H Nakamura; M Ilmonen; Christian R Lombardo; Taina Pihlajaniemi; Kari Alitalo; Kristiina Vuori
Interaction of endostatin with integrins implicated in angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1024-9.
2001: Pasi O Hägg; Timo Väisänen; Anne Tuomisto; Marko Rehn; Hongmin Tu; P Huhtala; Sinikka Eskelinen; Taina Pihlajaniemi
Type XIII collagen: a novel cell adhesion component present in a range of cell-matrix adhesions and in the intercalated discs between cardiac muscle cells.
Matrix biology : journal of the International Society for Matrix Biology 2001;19(8):727-42.
2001: Orlando Musso; Marko Rehn; Nathalie Théret; Bruno Turlin; P Bioulac-Sage; D Lotrian; Jean-Pierre Campion; Taina Pihlajaniemi; Bruno Clément
Tumor progression is associated with a significant decrease in the expression of the endostatin precursor collagen XVIII in human hepatocellular carcinomas.
Cancer research 2001;61(1):45-9.
2000: J Liétard; Nathalie Théret; Marko Rehn; Orlando Musso; D Dargère; Taina Pihlajaniemi; Bruno Clément
The promoter of the long variant of collagen XVIII, the precursor of endostatin, contains liver-specific regulatory elements.
Hepatology (Baltimore, Md.) 2000;32(6):1377-85.
2000: Lauri Eklund; Anu Muona; J Liétard; Taina Pihlajaniemi
Structure of the mouse type XV collagen gene, Col15a1, comparison with the human COL15A1 gene and functional analysis of the promoters of both genes.
Matrix biology : journal of the International Society for Matrix Biology 2000;19(6):489-500.
2000: Anne Snellman; Hongmin Tu; Timo Väisänen; Ari-Pekka Kvist; P Huhtala; Taina Pihlajaniemi
A short sequence in the N-terminal region is required for the trimerization of type XIII collagen and is conserved in other collagenous transmembrane proteins.
The EMBO journal 2000;19(19):5051-9.
2000: Minna Sandberg-Lall; Pasi O Hägg; I Wahlström; Taina Pihlajaniemi
Type XIII collagen is widely expressed in the adult and developing human eye and accentuated in the ciliary muscle, the optic nerve and the neural retina.
Experimental eye research 2000;70(4):401-10.
2000: Anne Snellman; M R Keränen; Pasi O Hägg; A Lamberg; J Kalervo Hiltunen; Kari I Kivirikko; Taina Pihlajaniemi
Type XIII collagen forms homotrimers with three triple helical collagenous domains and its association into disulfide-bonded trimers is enhanced by prolyl 4-hydroxylase.
The Journal of biological chemistry 2000;275(12):8936-44.
2000: I Keizer-Gunnink; A Vuorela; Johanna Myllyharju; Taina Pihlajaniemi; Kari I Kivirikko; Marten Veenhuis
Accumulation of properly folded human type III procollagen molecules in specific intracellular membranous compartments in the yeast Pichia pastoris.
Matrix biology : journal of the International Society for Matrix Biology 2000;19(1):29-36.
1999: Reijo J Linnola; Malin Sund; Riikka Ylönen; Taina Pihlajaniemi
Adhesion of soluble fibronectin, laminin, and collagen type IV to intraocular lens materials.
Journal of cataract and refractive surgery 1999;25(11):1486-91.
1999: A Vuorela; Johanna Myllyharju; Taina Pihlajaniemi; Kari I Kivirikko
Coexpression with collagen markedly increases the half-life of the recombinant human prolyl 4-hydroxylase tetramer in the yeast Pichia pastoris.
Matrix biology : journal of the International Society for Matrix Biology 1999;18(5):519-22.
1999: Sirkku Peltonen; M Hentula; Pasi O Hägg; Heli Ylä-Outinen; J Tuukkanen; Jouni Lakkakorpi; Marko Rehn; Taina Pihlajaniemi; Juha Peltonen
A novel component of epidermal cell-matrix and cell-cell contacts: transmembrane protein type XIII collagen.
The Journal of investigative dermatology 1999;113(4):635-42.
1999: Ari-Pekka Kvist; Anne Latvanlehto; Malin Sund; Nina Horelli-Kuitunen; Marko Rehn; Aarno Palotie; D Beier; Taina Pihlajaniemi
Complete exon-intron organization and chromosomal location of the gene for mouse type XIII collagen (col13a1) and comparison with its human homologue.
Matrix biology : journal of the International Society for Matrix Biology 1999;18(3):261-74.
1999: R Valtola; Petri Salven; Päivi Heikkilä; Jussi Taipale; Heikki Joensuu; Marko Rehn; Taina Pihlajaniemi; HA Weich; R deWaal; Kari Alitalo
VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer.
The American journal of pathology 1999;154(5):1381-90.
1998: Linda K Myers; David Douglass Brand; Xiu J Ye; Michael A Cremer; Edward F Rosloniec; Michael Bodo; Johanna Myllyharju; T Helaakoski; Minna Nokelainen; Taina Pihlajaniemi; Kari I Kivirikko; C L Yang; Leena Ala-Kokko; D J Prockop; Holger Notbohm; PP Fietzek; John M Stuart; Andrew H Kang
Characterization of recombinant type II collagen: arthritogenicity and tolerogenicity in DBA/1 mice.
Immunology 1998;95(4):631-9.
1998: Marko Rehn; Taina Pihlajaniemi; Kay Hofmann; P Bucher
The frizzled motif: in how many different protein families does it occur?
Trends in biochemical sciences 1998;23(11):415-7.
1998: J Saarela; Marko Rehn; Aarne Oikarinen; Helena Autio-Harmainen; Taina Pihlajaniemi
The short and long forms of type XVIII collagen show clear tissue specificities in their expression and location in basement membrane zones in humans.
The American journal of pathology 1998;153(2):611-26.
1998: Pasi Hägg; Anu Muona; J Liétard; Sirpa Kivirikko; Taina Pihlajaniemi
Complete exon-intron organization of the human gene for the alpha1 chain of type XV collagen (COL15A1) and comparison with the homologous COL18A1 gene.
The Journal of biological chemistry 1998;273(28):17824-31.
1998: Orlando Musso; Marko Rehn; J Saarela; Nathalie Théret; J Liétard; D Lotrian; Jean-Pierre Campion; Taina Pihlajaniemi; Bruno Clément
Collagen XVIII is localized in sinusoids and basement membrane zones and expressed by hepatocytes and activated stellate cells in fibrotic human liver.
Hepatology (Baltimore, Md.) 1998;28(1):98-107.
1998: Pasi O Hägg; Marko Rehn; P Huhtala; Timo Väisänen; Minna Tamminen; Taina Pihlajaniemi
Type XIII collagen is identified as a plasma membrane protein.
The Journal of biological chemistry 1998;273(25):15590-7.
1998: Kari I Kivirikko; Taina Pihlajaniemi
Collagen hydroxylases and the protein disulfide isomerase subunit of prolyl 4-hydroxylases.
Advances in enzymology and related areas of molecular biology 1998;72():325-98.
1998: Minna Nokelainen; T Helaakoski; Johanna Myllyharju; Holger Notbohm; Taina Pihlajaniemi; PP Fietzek; Kari I Kivirikko
Expression and characterization of recombinant human type II collagens with low and high contents of hydroxylysine and its glycosylated forms.
Matrix biology : journal of the International Society for Matrix Biology 1998;16(6):329-38.
1998: J Saarela; Ritva Ylikärppä; Marko Rehn; S Purmonen; Taina Pihlajaniemi
Complete primary structure of two variant forms of human type XVIII collagen and tissue-specific differences in the expression of the corresponding transcripts.
Matrix biology : journal of the International Society for Matrix Biology 1998;16(6):319-28.
1997: Nina Horelli-Kuitunen; Ari-Pekka Kvist; T Helaakoski; Kari I Kivirikko; Taina Pihlajaniemi; Aarno Palotie
The order and transcriptional orientation of the human COL13A1 and P4HA genes on chromosome 10 long arm determined by high-resolution FISH.
Genomics 1997;46(2):299-302.
1997: A Vuorela; Johanna Myllyharju; Ritva Nissi; Taina Pihlajaniemi; Kari I Kivirikko
Assembly of human prolyl 4-hydroxylase and type III collagen in the yeast pichia pastoris: formation of a stable enzyme tetramer requires coexpression with collagen and assembly of a stable collagen requires coexpression with prolyl 4-hydroxylase.
The EMBO journal 1997;16(22):6702-12.
1997: Pasi Hägg; Nina Horelli-Kuitunen; Lauri Eklund; Aarno Palotie; Taina Pihlajaniemi
Cloning of mouse type XV collagen sequences and mapping of the corresponding gene to 4B1-3. Comparison of mouse and human alpha 1 (XV) collagen sequences indicates divergence in the number of small collagenous domains.
Genomics 1997;45(1):31-41.
1997: Johanna Myllyharju; A Lamberg; Holger Notbohm; PP Fietzek; Taina Pihlajaniemi; Kari I Kivirikko
Expression of wild-type and modified proalpha chains of human type I procollagen in insect cells leads to the formation of stable [alpha1(I)]2alpha2(I) collagen heterotrimers and [alpha1(I)]3 homotrimers but not [alpha2(I)]3 homotrimers.
The Journal of biological chemistry 1997;272(35):21824-30.
1997: P Annunen; T Helaakoski; Johanna Myllyharju; Johanna Veijola; Taina Pihlajaniemi; Kari I Kivirikko
Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer.
The Journal of biological chemistry 1997;272(28):17342-8.
1997: Pasi Hägg; Pasi O Hägg; Sirkku Peltonen; Helena Autio-Harmainen; Taina Pihlajaniemi
Location of type XV collagen in human tissues and its accumulation in the interstitial matrix of the fibrotic kidney.
The American journal of pathology 1997;150(6):2075-86.
1997: Sirkku Peltonen; Marko Rehn; Taina Pihlajaniemi
Alternative splicing of mouse alpha1(XIII) collagen RNAs results in at least 17 different transcripts, predicting alpha1(XIII) collagen chains with length varying between 651 and 710 amino acid residues.
DNA and cell biology 1997;16(2):227-34.
1996: Juha Veijola; P Annunen; P Koivunen; A P Page; Taina Pihlajaniemi; Kari I Kivirikko
Baculovirus expression of two protein disulphide isomerase isoforms from Caenorhabditis elegans and characterization of prolyl 4-hydroxylases containing one of these polypeptides as their beta subunit.
The Biochemical journal 1996;317 ( Pt 3)():721-9.
1996: P Koivunen; T Helaakoski; P Annunen; Juha Veijola; S Räisänen; Taina Pihlajaniemi; Kari I Kivirikko
ERp60 does not substitute for protein disulphide isomerase as the beta-subunit of prolyl 4-hydroxylase.
The Biochemical journal 1996;316 ( Pt 2)():599-605.
1996: A Lamberg; T Helaakoski; Johanna Myllyharju; Sirkku Peltonen; Holger Notbohm; Taina Pihlajaniemi; Kari I Kivirikko
Characterization of human type III collagen expressed in a baculovirus system. Production of a protein with a stable triple helix requires coexpression with the two types of recombinant prolyl 4-hydroxylase subunit.
The Journal of biological chemistry 1996;271(20):11988-95.
1996: Juha Veijola; Taina Pihlajaniemi; Kari I Kivirikko
Co-expression of the alpha subunit of human prolyl 4-hydroxylase with BiP polypeptide in insect cells leads to the formation of soluble and insoluble complexes. Soluble alpha-subunit-BiP complexes have no prolyl 4-hydroxylase activity.
The Biochemical journal 1996;315 ( Pt 2)():613-8.
1996: A Lamberg; Matti Jauhiainen; Jari Metso; Christian Ehnholm; C Shoulders; J Scott; Taina Pihlajaniemi; Kari I Kivirikko
The role of protein disulphide isomerase in the microsomal triacylglycerol transfer protein does not reside in its isomerase activity.
The Biochemical journal 1996;315 ( Pt 2)():533-6.
1996: R Kemppainen; E R Hämäläinen; Helena Kuivaniemi; Gerard Tromp; Taina Pihlajaniemi; Kari I Kivirikko
Expression of mRNAs for lysyl oxidase and type III procollagen in cultured fibroblasts from patients with the Menkes and occipital horn syndromes as determined by quantitative polymerase chain reaction.
Archives of biochemistry and biophysics 1996;328(1):101-6.
1996: Marko Rehn; E Hintikka; Taina Pihlajaniemi
Characterization of the mouse gene for the alpha 1 chain of type XVIII collagen (Col18a1) reveals that the three variant N-terminal polypeptide forms are transcribed from two widely separated promoters.
Genomics 1996;32(3):436-46.
1996: E R Hämäläinen; A Renieri; C Pecoraro; M De Marchi; Taina Pihlajaniemi
Unequal homologous crossing over resulting in duplication of 36 base pairs within exon 47 of the COL4A5 gene in a family with Alport syndrome.
Human mutation 1996;8(3):265-9.
1996: Taina Pihlajaniemi
Molecular properties of the glomerular basement membrane.
Contributions to nephrology 1996;117():46-79.
1995: Sirpa Kivirikko; J Saarela; Jeanne C Myers; Helena Autio-Harmainen; Taina Pihlajaniemi
Distribution of type XV collagen transcripts in human tissue and their production by muscle cells and fibroblasts.
The American journal of pathology 1995;147(5):1500-9.
1995: E R Hämäläinen; R Kemppainen; Helena Kuivaniemi; Gerard Tromp; A Vaheri; Taina Pihlajaniemi; Kari I Kivirikko
Quantitative polymerase chain reaction of lysyl oxidase mRNA in malignantly transformed human cell lines demonstrates that their low lysyl oxidase activity is due to low quantities of its mRNA and low levels of transcription of the respective gene.
The Journal of biological chemistry 1995;270(37):21590-3.
1995: T Helaakoski; P Annunen; Kristiina Vuori; I A MacNeil; Taina Pihlajaniemi; Kari I Kivirikko
Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4427-31.
1995: A Lamberg; Taina Pihlajaniemi; Kari I Kivirikko
Site-directed mutagenesis of the alpha subunit of human prolyl 4-hydroxylase. Identification of three histidine residues critical for catalytic activity.
The Journal of biological chemistry 1995;270(17):9926-31.
1995: Marko Rehn; Taina Pihlajaniemi
Identification of three N-terminal ends of type XVIII collagen chains and tissue-specific differences in the expression of the corresponding transcripts. The longest form contains a novel motif homologous to rat and Drosophila frizzled proteins.
The Journal of biological chemistry 1995;270(9):4705-11.
1995: Taina Pihlajaniemi; Marko Rehn
Two new collagen subgroups: membrane-associated collagens and types XV and XVII.
Progress in nucleic acid research and molecular biology 1995;50():225-62.
1994: T Helaakoski; Juha Veijola; Kristiina Vuori; Marko Rehn; L T Chow; P Taillon-Miller; Kari I Kivirikko; Taina Pihlajaniemi
Structure and expression of the human gene for the alpha subunit of prolyl 4-hydroxylase. The two alternatively spliced types of mRNA correspond to two homologous exons the sequences of which are expressed in a variety of tissues.
The Journal of biological chemistry 1994;269(45):27847-54.
1994: Juha Veijola; P Koivunen; P Annunen; Taina Pihlajaniemi; Kari I Kivirikko
Cloning, baculovirus expression, and characterization of the alpha subunit of prolyl 4-hydroxylase from the nematode Caenorhabditis elegans. This alpha subunit forms an active alpha beta dimer with the human protein disulfide isomerase/beta subunit.
The Journal of biological chemistry 1994;269(43):26746-53.
1994: Marko Rehn; E Hintikka; Taina Pihlajaniemi
Primary structure of the alpha 1 chain of mouse type XVIII collagen, partial structure of the corresponding gene, and comparison of the alpha 1(XVIII) chain with its homologue, the alpha 1(XV) collagen chain.
The Journal of biological chemistry 1994;269(19):13929-35.
1994: Marko Rehn; Taina Pihlajaniemi
Alpha 1(XVIII), a collagen chain with frequent interruptions in the collagenous sequence, a distinct tissue distribution, and homology with type XV collagen.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4234-8.
1994: Sirpa Kivirikko; P Heinämäki; Marko Rehn; N Honkanen; Jeanne C Myers; Taina Pihlajaniemi
Primary structure of the alpha 1 chain of human type XV collagen and exon-intron organization in the 3' region of the corresponding gene.
The Journal of biological chemistry 1994;269(7):4773-9.
1993: M Juvonen; Taina Pihlajaniemi; Helena Autio-Harmainen
Location and alternative splicing of type XIII collagen RNA in the early human placenta.
Laboratory investigation; a journal of technical methods and pathology 1993;69(5):541-51.
1993: E R Hämäläinen; R Kemppainen; Taina Pihlajaniemi; Kari I Kivirikko
Structure of the human lysyl oxidase gene.
Genomics 1993;17(3):544-8.
1993: Kaisa Tasanen; Jorma Oikarinen; Kari I Kivirikko; Taina Pihlajaniemi
Interaction of transcription factor Sp1 with the promoter of the gene for the multifunctional protein disulphide isomerase polypeptide.
The Biochemical journal 1993;292 ( Pt 1)():41-5.
1992: M Juvonen; M Sandberg; Taina Pihlajaniemi
Patterns of expression of the six alternatively spliced exons affecting the structures of the COL1 and NC2 domains of the alpha 1(XIII) collagen chain in human tissues and cell lines.
The Journal of biological chemistry 1992;267(34):24700-7.
1992: M Juvonen; Taina Pihlajaniemi
Characterization of the spectrum of alternative splicing of alpha 1 (XIII) collagen transcripts in HT-1080 cells and calvarial tissue resulted in identification of two previously unidentified alternatively spliced sequences, one previously unidentified exon, and nine new mRNA variants.
The Journal of biological chemistry 1992;267(34):24693-9.
1992: Kristiina Vuori; Taina Pihlajaniemi; Raili Myllylä; Kari I Kivirikko
Site-directed mutagenesis of human protein disulphide isomerase: effect on the assembly, activity and endoplasmic reticulum retention of human prolyl 4-hydroxylase in Spodoptera frugiperda insect cells.
The EMBO journal 1992;11(11):4213-7.
1992: Jeanne C Myers; Sirpa Kivirikko; M K Gordon; A S Dion; Taina Pihlajaniemi
Identification of a previously unknown human collagen chain, alpha 1(XV), characterized by extensive interruptions in the triple-helical region.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10144-8.
1992: Kay Huebner; Linda Cannizzaro; Ethylin Jabs; Sirpa Kivirikko; H Manzone; Taina Pihlajaniemi; Jeanne C Myers
Chromosomal assignment of a gene encoding a new collagen type (COL15A1) to 9q21 --> q22.
Genomics 1992;14(2):220-4.
1992: Kristiina Vuori; Taina Pihlajaniemi; Minna Marttila; Kari I Kivirikko
Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7467-70.
1992: Kaisa Tasanen; Jorma Oikarinen; Kari I Kivirikko; Taina Pihlajaniemi
Promoter of the gene for the multifunctional protein disulfide isomerase polypeptide. Functional significance of the six CCAAT boxes and other promoter elements.
The Journal of biological chemistry 1992;267(16):11513-9.
1992: Kristiina Vuori; Raili Myllylä; Taina Pihlajaniemi; Kari I Kivirikko
Expression and site-directed mutagenesis of human protein disulfide isomerase in Escherichia coli. This multifunctional polypeptide has two independently acting catalytic sites for the isomerase activity.
The Journal of biological chemistry 1992;267(11):7211-4.
1991: E R Hämäläinen; T A Jones; Denise Sheer; K Taskinen; Taina Pihlajaniemi; Kari I Kivirikko
Molecular cloning of human lysyl oxidase and assignment of the gene to chromosome 5q23.3-31.2.
Genomics 1991;11(3):508-16.
1991: Taina Pihlajaniemi
Concept of one gene one protein revisited: protein disulphide isomerase, a multifunctional protein.
Annals of medicine 1991;23(4):393-4.
1991: L Tikka; Outi Elomaa; Taina Pihlajaniemi; Karl Tryggvason
Human alpha 1 (XIII) collagen gene. Multiple forms of the gene transcripts are generated through complex alternative splicing of several short exons.
The Journal of biological chemistry 1991;266(26):17713-9.
1991: P M Palosaari; Mauno Vihinen; Pekka Mäntsälä; Stefan E H Alexson; Taina Pihlajaniemi; J Kalervo Hiltunen
Amino acid sequence similarities of the mitochondrial short chain delta 3, delta 2-enoyl-CoA isomerase and peroxisomal multifunctional delta 3, delta 2-enoyl-CoA isomerase, 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase enzyme in rat liver. The proposed occurrence of isomerization and hydration in the same catalytic domain of the multifunctional enzyme.
The Journal of biological chemistry 1991;266(17):10750-3.
1991: Helena Autio-Harmainen; M Sandberg; Taina Pihlajaniemi; E Vuorio
Synthesis of laminin and type IV collagen by trophoblastic cells and fibroblastic stromal cells in the early human placenta.
Laboratory investigation; a journal of technical methods and pathology 1991;64(4):483-91.
1991: Raili Myllylä; Taina Pihlajaniemi; L Pajunen; Taina Turpeenniemi-Hujanen; Kari I Kivirikko
Molecular cloning of chick lysyl hydroxylase. Little homology in primary structure to the two types of subunit of prolyl 4-hydroxylase.
The Journal of biological chemistry 1991;266(5):2805-10.
1991: Taina Pihlajaniemi; Raili Myllylä; Kari I Kivirikko
Prolyl 4-hydroxylase and its role in collagen synthesis.
Journal of hepatology 1991;13 Suppl 3():S2-7.
1991: L Pajunen; T A Jones; A Goddard; Denise Sheer; E Solomon; Taina Pihlajaniemi; Kari I Kivirikko
Regional assignment of the human gene coding for a multifunctional polypeptide (P4HB) acting as the beta-subunit of prolyl 4-hydroxylase and the enzyme protein disulfide isomerase to 17q25.
Cytogenetics and cell genetics 1991;56(3-4):165-8.
1990: Taina Pihlajaniemi; M Tamminen
The alpha 1 chain of type XIII collagen consists of three collagenous and four noncollagenous domains, and its primary transcript undergoes complex alternative splicing.
The Journal of biological chemistry 1990;265(28):16922-8.
1990: Taina Pihlajaniemi; E R Pohjolainen; Jeanne C Myers
Complete primary structure of the triple-helical region and the carboxyl-terminal domain of a new type IV collagen chain, alpha 5(IV).
The Journal of biological chemistry 1990;265(23):13758-66.
1990: T Helaakoski; L Pajunen; Kari I Kivirikko; Taina Pihlajaniemi
Increases in mRNA concentrations of the alpha and beta subunits of prolyl 4-hydroxylase accompany increased gene expression of type IV collagen during differentiation of mouse F9 cells.
The Journal of biological chemistry 1990;265(20):11413-6.
1990: Jeanne C Myers; T A Jones; E R Pohjolainen; A S Kadri; A D Goddard; Denise Sheer; E Solomon; Taina Pihlajaniemi
Molecular cloning of alpha 5(IV) collagen and assignment of the gene to the region of the X chromosome containing the Alport syndrome locus.
American journal of human genetics 1990;46(6):1024-33.
1990: K Karvonen; Leena Ala-Kokko; Taina Pihlajaniemi; T Helaakoski; S Henke; V Günzler; Kari I Kivirikko; E R Savolainen
Specific inactivation of prolyl 4-hydroxylase and inhibition of collagen synthesis by oxaproline-containing peptides in cultured human skin fibroblasts.
The Journal of biological chemistry 1990;265(15):8415-9.
1990: Kari I Kivirikko; T Helaakoski; Kaisa Tasanen; Kristiina Vuori; Raili Myllylä; T Parkkonen; Taina Pihlajaniemi
Molecular biology of prolyl 4-hydroxylase.
Annals of the New York Academy of Sciences 1990;580():132-42.
1989: L Pajunen; T A Jones; T Helaakoski; Taina Pihlajaniemi; E Solomon; Denise Sheer; Kari I Kivirikko
Assignment of the gene coding for the alpha-subunit of prolyl 4-hydroxylase to human chromosome region 10q21.3-23.1.
American journal of human genetics 1989;45(6):829-34.
1989: T Helaakoski; Kristiina Vuori; Raili Myllylä; Kari I Kivirikko; Taina Pihlajaniemi
Molecular cloning of the alpha-subunit of human prolyl 4-hydroxylase: the complete cDNA-derived amino acid sequence and evidence for alternative splicing of RNA transcripts.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4392-6.
1989: Kari I Kivirikko; Raili Myllylä; Taina Pihlajaniemi
Protein hydroxylation: prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multifunctional subunit.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(5):1609-17.
1989: Taina Pihlajaniemi; J McKeon; S Gay; R Gay; W J de Wet; Jeanne C Myers; Darwin J Prockop
Increased expression of the gene for the pro alpha 1(IV) chain of basement-membrane procollagen in cultured skin fibroblasts from two variants of osteogenesis imperfecta.
The Biochemical journal 1989;257(2):439-45.
1989: L Pajunen; Minna Tamminen; E Solomon; Taina Pihlajaniemi
Assignment of the gene coding for the alpha 1 chain of collagen type XIII (COL13A1) to human chromosome region 10q11----qter.
Cytogenetics and cell genetics 1989;52(3-4):190-3.
1988: T Parkkonen; Kari I Kivirikko; Taina Pihlajaniemi
Molecular cloning of a multifunctional chicken protein acting as the prolyl 4-hydroxylase beta-subunit, protein disulphide-isomerase and a cellular thyroid-hormone-binding protein. Comparison of cDNA-deduced amino acid sequences with those in other species.
The Biochemical journal 1988;256(3):1005-11.
1988: Kaisa Tasanen; T Parkkonen; L T Chow; Kari I Kivirikko; Taina Pihlajaniemi
Characterization of the human gene for a polypeptide that acts both as the beta subunit of prolyl 4-hydroxylase and as protein disulfide isomerase.
The Journal of biological chemistry 1988;263(31):16218-24.
1988: L Tikka; Taina Pihlajaniemi; P Henttu; Darwin J Prockop; Karl Tryggvason
Gene structure for the alpha 1 chain of a human short-chain collagen (type XIII) with alternatively spliced transcripts and translation termination codon at the 5' end of the last exon.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7491-5.
1988: L Pajunen; Raili Myllylä; T Helaakoski; Taina Pihlajaniemi; Kaisa Tasanen; M Höyhtyä; K Tryggvason; E Solomon; Kari I Kivirikko
Assignment of the gene coding for both the beta-subunit of prolyl 4-hydroxylase and the enzyme disulfide isomerase to human chromosome region 17p11----qter.
Cytogenetics and cell genetics 1988;47(1-2):37-41.
1987: Leena Ala-Kokko; Taina Pihlajaniemi; Jeanne C Myers; Kari I Kivirikko; E R Savolainen
Gene expression of type I, III and IV collagens in hepatic fibrosis induced by dimethylnitrosamine in the rat.
The Biochemical journal 1987;244(1):75-9.
1987: J Koivu; Raili Myllylä; T Helaakoski; Taina Pihlajaniemi; Kaisa Tasanen; Kari I Kivirikko
A single polypeptide acts both as the beta subunit of prolyl 4-hydroxylase and as a protein disulfide-isomerase.
The Journal of biological chemistry 1987;262(14):6447-9.
1987: Taina Pihlajaniemi; T Helaakoski; Kaisa Tasanen; Raili Myllylä; M L Huhtala; J Koivu; Kari I Kivirikko
Molecular cloning of the beta-subunit of human prolyl 4-hydroxylase. This subunit and protein disulphide isomerase are products of the same gene.
The EMBO journal 1987;6(3):643-9.
1986: R Soininen; L Tikka; L Chow; Taina Pihlajaniemi; Markku T Kurkinen; Darwin J Prockop; C D Boyd; Karl Tryggvason
Large introns in the 3' end of the gene for the pro alpha 1 (IV) chain of human basement membrane collagen.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(6):1568-72.
1985: Darwin J Prockop; M L Chu; W de Wet; Jeanne C Myers; Taina Pihlajaniemi; Francesco Ramirez; M Sippola
Mutations in osteogenesis imperfecta leading to the synthesis of abnormal type I procollagens.
Annals of the New York Academy of Sciences 1985;460():289-97.
1983: Raili Myllylä; J Koivu; Taina Pihlajaniemi; Kari I Kivirikko
Protein disulphide-isomerase activity in various cells synthesizing collagen.
European journal of biochemistry / FEBS 1983;134(1):7-11.