FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Linda Pilarski

Research Profile

Disorders

Anatomy

Chemicals & Drugs

Physiology

Cell Differentiation

Procedures

Reverse Transcriptase Polymerase Chain Reaction

Co-author Network

Publications

TOP 3
Lorri D Martin; Andrew R Belch; Jana Harizanova; Sabine Mai; Christiaan H Righolt; George Zhu; Linda M Pilarski
Differential nuclear organization of translocation-prone genes in nonmalignant B cells from patients with t(14;16) as compared with t(4;14) or t(11;14) myeloma.
Jitra Kriangkum; Andrew R Belch; Amanda Warkinton; Linda M Pilarski
Alteration of introns in a hyaluronan synthase 1 (HAS1) minigene convert pre-Mrna splicing to the aberrant pattern in multiple myeloma (MM): MM patients harbor similar changes.
Lorri D Martin; Andrew R Belch; Jana Harizanova; Sabine Mai; Christiaan H Righolt; George Zhu; Linda M Pilarski
Differential positioning and close spatial proximity of translocation-prone genes in nonmalignant B-cells from multiple myeloma patients.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Linda Pilarski (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Lorri D Martin; Andrew R Belch; Jana Harizanova; Sabine Mai; Christiaan H Righolt; George Zhu; Linda M Pilarski
Differential nuclear organization of translocation-prone genes in nonmalignant B cells from patients with t(14;16) as compared with t(4;14) or t(11;14) myeloma.
Genes, chromosomes & cancer 2013;52(6):523-37.
2013: Jitra Kriangkum; Andrew R Belch; Amanda Warkinton; Linda M Pilarski
Alteration of introns in a hyaluronan synthase 1 (HAS1) minigene convert pre-Mrna splicing to the aberrant pattern in multiple myeloma (MM): MM patients harbor similar changes.
PloS one 2013;8(1):e53469.
2012: Lorri D Martin; Andrew R Belch; Jana Harizanova; Sabine Mai; Christiaan H Righolt; George Zhu; Linda M Pilarski
Differential positioning and close spatial proximity of translocation-prone genes in nonmalignant B-cells from multiple myeloma patients.
Genes, chromosomes & cancer 2012;51(8):727-42.
2012: Carina S Debes Marun; Andrew R Belch; Linda M Pilarski
In multiple myeloma, bone-marrow lymphocytes harboring the same chromosomal abnormalities as autologous plasma cells predict poor survival.
American journal of hematology 2012;87(6):579-87.
2012: Dammika P Manage; Yuen C Morrissey; Kanti Pabbaraju; Alexey Atrazhev; H John Crabtree; Ann L Edwards; Jana Lauzon; A Stickel; Stephanie K Yanow; George Zahariadis; Linda M Pilarski
A miniaturized and integrated gel post platform for multiparameter PCR detection of herpes simplex viruses from raw genital swabs.
Lab on a chip 2012;12(9):1664-71.
2012: Kyle J Thulien; Tony Reiman; Andrew R Belch; Linda M Pilarski
In non-transplant patients with multiple myeloma, the pre-treatment level of clonotypic cells predicts event-free survival.
Molecular cancer 2012;11():78.
2011: Inka Toman; Jonathan Loree; Alexander C Klimowicz; Nizar Bahlis; Raymond Lai; Andrew R Belch; Linda M Pilarski; Tony Reiman
Expression and prognostic significance of Oct2 and Bob1 in multiple myeloma: implications for targeted therapeutics.
Leukemia & lymphoma 2011;52(4):659-67.
2011: Julia Kirshner; Kyle J Thulien; Jitra Kriangkum; Sarah Motz; Andrew R Belch; Linda M Pilarski
In a patient with biclonal Waldenstrom macroglobulinemia only one clone expands in three-dimensional culture and includes putative cancer stem cells.
Leukemia & lymphoma 2011;52(2):285-9.
2010: Alexey Atrazhev; Dammika P Manage; A Stickel; H John Crabtree; Linda M Pilarski; Jason P Acker
In-gel technology for PCR genotyping and pathogen detection.
Analytical chemistry 2010;82(19):8079-87.
2010: Lorri D Martin; Andrew R Belch; Linda M Pilarski
Promiscuity of translocation partners in multiple myeloma.
Journal of cellular biochemistry 2010;109(6):1085-94.
2010: Linda M Pilarski; Patrick M Pilarski; Andrew R Belch
Multiple myeloma may include microvessel endothelial cells of malignant origin.
Leukemia & lymphoma 2010;51(4):592-7.
2009: Anirban Ghosh; Hemalatha Kuppusamy; Linda M Pilarski
Aberrant splice variants of HAS1 (Hyaluronan Synthase 1) multimerize with and modulate normally spliced HAS1 protein: a potential mechanism promoting human cancer.
The Journal of biological chemistry 2009;284(28):18840-50.
2009: Sophia Adamia; Patrick M Pilarski; Andrew R Belch; Linda M Pilarski
Genetic abnormalities in Waldenström's macroglobulinemia.
Clinical lymphoma & myeloma 2009;9(1):30-2.
2008: Sophia Adamia; Amanda A Reichert; Hemalatha Kuppusamy; Jitra Kriangkum; Anirban Ghosh; Jennifer J Hodges; Patrick M Pilarski; Steve P Treon; Michael J Mant; Tony Reiman; Andrew R Belch; Linda M Pilarski
Inherited and acquired variations in the hyaluronan synthase 1 (HAS1) gene may contribute to disease progression in multiple myeloma and Waldenstrom macroglobulinemia.
Blood 2008;112(13):5111-21.
2008: Viet N Hoang; Govind V Kaigala; Alexey Atrazhev; Linda M Pilarski; Christopher Backhouse
Strategies for enhancing the speed and integration of microchip genetic amplification.
Electrophoresis 2008;29(23):4684-94.
2008: Vincent J Sieben; Carina S Debes-Marun; Linda M Pilarski; Christopher Backhouse
An integrated microfluidic chip for chromosome enumeration using fluorescence in situ hybridization.
Lab on a chip 2008;8(12):2151-6.
2008: Julia Kirshner; Kyle J Thulien; Lorri D Martin; Carina Debes Marun; Tony Reiman; Andrew R Belch; Linda M Pilarski
A unique three-dimensional model for evaluating the impact of therapy on multiple myeloma.
Blood 2008;112(7):2935-45.
2008: Brian J Taylor; Jitra Kriangkum; Julie A Pittman; Michael J Mant; Tony Reiman; Andrew R Belch; Linda M Pilarski
Analysis of clonotypic switch junctions reveals multiple myeloma originates from a single class switch event with ongoing mutation in the isotype-switched progeny.
Blood 2008;112(5):1894-903.
2008: Govind V Kaigala; Viet N Hoang; Alex Stickel; Jana Lauzon; Dammika Manage; Linda M Pilarski; Christopher Backhouse
An inexpensive and portable microchip-based platform for integrated RT-PCR and capillary electrophoresis.
The Analyst 2008;133(3):331-8.
2008: Robert Evans; Claudia Naber; Tara Steffler; Tamara Checkland; Jonathan J Keats; Christopher Maxwell; Troy Perry; Heidi Chau; Andrew R Belch; Linda M Pilarski; Tony Reiman
Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells.
Leukemia & lymphoma 2008;49(3):559-69.
2008: Robert P Evans; Claudia Naber; Tara Steffler; Tamara Checkland; Christopher A Maxwell; Jonathan J Keats; Andrew R Belch; Linda M Pilarski; Raymond Lai; Tony Reiman
The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma.
British journal of haematology 2008;140(3):295-302.
2008: Linda M Pilarski; Patrick M Pilarski; Heddy Zola; Penelope Adamson; Eva Baigorri; Michael J Mant; Andrew R Belch
Multiple Myeloma Includes Phenotypically Defined Subsets of Clonotypic CD20+ B Cells that Persist During Treatment with Rituximab.
Clinical medicine. Oncology 2008;2():275-87.
2007: Daniel Ditzel Santos; Allen W Ho; Olivier Tournilhac; Evdoxia Hatjiharissi; Xavier Leleu; Lian Xu; Pierfrancesco Tassone; Paola Neri; Zachary R Hunter; Mariana A Z Chemaly; Andrew R Branagan; Robert J Manning; Christopher J Patterson; Anne-Sophie Moreau; Bryan Ciccarelli; Sophia Adamia; Jitra Kriangkum; Jeffery L Kutok; Yu-Tzu Tai; Jiangwen Zhang; Linda M Pilarski; Kenneth C Anderson; Nikhil C Munshi; Steve P Treon
Establishment of BCWM.1 cell line for Waldenström's macroglobulinemia with productive in vivo engraftment in SCID-hu mice.
Experimental hematology 2007;35(9):1366-75.
2007: Jeeshan Chowdhury; Govind V Kagiala; Sudeep Pushpakom; Jana Lauzon; Alistair Makin; Alexey Atrazhev; Alex Stickel; William G Newman; Christopher Backhouse; Linda M Pilarski
Microfluidic platform for single nucleotide polymorphism genotyping of the thiopurine S-methyltransferase gene to evaluate risk for adverse drug events.
The Journal of molecular diagnostics : JMD 2007;9(4):521-9.
2007: Jaron VanDijken; Govind V Kaigala; Jana Lauzon; Alexey Atrazhev; Sophia Adamia; Brian J Taylor; Tony Reiman; Andrew R Belch; Christopher Backhouse; Linda M Pilarski
Microfluidic chips for detecting the t(4;14) translocation and monitoring disease during treatment using reverse transcriptase-polymerase chain reaction analysis of IgH-MMSET hybrid transcripts.
The Journal of molecular diagnostics : JMD 2007;9(3):358-67.
2007: V J Sieben; C S Debes Marun; P M Pilarski; Govind V Kaigala; Linda M Pilarski; Christopher Backhouse
FISH and chips: chromosomal analysis on microfluidic platforms.
IET nanobiotechnology / IET 2007;1(3):27-35.
2007: Yijiang Shi; Tony Reiman; Weiqun Li; Christopher A Maxwell; Subrata Sen; Linda M Pilarski; Tracy R Daniels; Manuel L Penichet; Rick Feldman; Alan Lichtenstein
Targeting aurora kinases as therapy in multiple myeloma.
Blood 2007;109(9):3915-21.
2007: Jitra Kriangkum; Brian J Taylor; Steve P Treon; Michael J Mant; Tony Reiman; Andrew R Belch; Linda M Pilarski
Molecular characterization of Waldenstrom's macroglobulinemia reveals frequent occurrence of two B-cell clones having distinct IgH VDJ sequences.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):2005-13.
2006: Jonathan J Keats; Tony Reiman; Andrew R Belch; Linda M Pilarski
Ten years and counting: so what do we know about t(4;14)(p16;q32) multiple myeloma.
Leukemia & lymphoma 2006;47(11):2289-300.
2006: Govind V Kaigala; Ryan J Huskins; Jutta K Preiksaitis; Xiaoli L Pang; Linda M Pilarski; Christopher Backhouse
Automated screening using microfluidic chip-based PCR and product detection to assess risk of BK virus-associated nephropathy in renal transplant recipients.
Electrophoresis 2006;27(19):3753-63.
2006: Jitra Kriangkum; Brian J Taylor; Erin Strachan; Michael J Mant; Tony Reiman; Andrew R Belch; Linda M Pilarski
Impaired class switch recombination (CSR) in Waldenstrom macroglobulinemia (WM) despite apparently normal CSR machinery.
Blood 2006;107(7):2920-7.
2005: Brian J Taylor; Tony Reiman; Julie A Pittman; Jonathan J Keats; Diederik R H de Bruijn; Michael J Mant; Andrew R Belch; Linda M Pilarski
SSX cancer testis antigens are expressed in most multiple myeloma patients: co-expression of SSX1, 2, 4, and 5 correlates with adverse prognosis and high frequencies of SSX-positive PCs.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2005;28(6):564-75.
2005: Linda M Pilarski; Jana Lauzon; Erin Strachan; Sophia Adamia; Alexey Atrazhev; Andrew R Belch; Christopher Backhouse
Sensitive detection using microfluidics technology of single cell PCR products from high and low abundance IgH VDJ templates in multiple myeloma.
Journal of immunological methods 2005;305(1):94-105.
2005: Sophia Adamia; Tony Reiman; Mary Crainie; Michael J Mant; Andrew R Belch; Linda M Pilarski
Intronic splicing of hyaluronan synthase 1 (HAS1): a biologically relevant indicator of poor outcome in multiple myeloma.
Blood 2005;105(12):4836-44.
2005: Jonathan J Keats; Christopher A Maxwell; Brian J Taylor; Michael Hendzel; Marta Chesi; P Leif Bergsagel; Loree Larratt; Michael J Mant; Tony Reiman; Andrew R Belch; Linda M Pilarski
Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients.
Blood 2005;105(10):4060-9.
2005: Sophia Adamia; Steve P Treon; Tony Reiman; Olivier Tournilhac; Carrie McQuarrie; Michael J Mant; Andrew R Belch; Linda M Pilarski
Potential impact of a single nucleotide polymorphism in the hyaluronan synthase 1 gene in Waldenstrom's macroglobulinemia.
Clinical lymphoma 2005;5(4):253-6.
2005: Jitra Kriangkum; Brian J Taylor; Tony Reiman; Andrew R Belch; Linda M Pilarski
Origins of Waldenstrom's macroglobulinemia: does it arise from an unusual B-cell precursor?
Clinical lymphoma 2005;5(4):217-9.
2005: Sophia Adamia; Christopher A Maxwell; Linda M Pilarski
Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.
Current drug targets. Cardiovascular & haematological disorders 2005;5(1):3-14.
2005: Christopher A Maxwell; Jonathan J Keats; Andrew R Belch; Linda M Pilarski; Tony Reiman
Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity.
Cancer research 2005;65(3):850-60.
2005: Christopher A Maxwell; Linda M Pilarski
A potential role for centrosomal deregulation within IgH translocation-positive myeloma.
Medical hypotheses 2005;65(5):915-21.
2005: Brian J Taylor; Jitra Kriangkum; Erin Strachan; Juanita M Wizniak; Linda M Pilarski
Identification of clonotypic IgH VDJ sequences in multiple myeloma.
Methods in molecular medicine 2005;113():121-44.
2004: Jitra Kriangkum; Brian J Taylor; Steve P Treon; Michael J Mant; Andrew R Belch; Linda M Pilarski
Clonotypic IgM V/D/J sequence analysis in Waldenstrom macroglobulinemia suggests an unusual B-cell origin and an expansion of polyclonal B cells in peripheral blood.
Blood 2004;104(7):2134-42.
2004: Esther G Cen; Colin Dalton; Youlan Li; Sophia Adamia; Linda M Pilarski; Karan V I S Kaler
A combined dielectrophoresis, traveling wave dielectrophoresis and electrorotation microchip for the manipulation and characterization of human malignant cells.
Journal of microbiological methods 2004;58(3):387-401.
2004: Christopher A Maxwell; Erik Rasmussen; Fenghuang Zhan; Jonathan J Keats; Sophia Adamia; Erin Strachan; Mary Crainie; Ronald Walker; Andrew R Belch; Linda M Pilarski; Bart Barlogie; John Shaughnessy; Tony Reiman
RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma.
Blood 2004;104(4):1151-8.
2004: Rafael Fonseca; Bart Barlogie; Regis Bataille; Christian Bastard; P Leif Bergsagel; Marta Chesi; Faith E Davies; Johannes Drach; Philip R Greipp; Ilan R Kirsch; W Michael Kuehl; Jesus M Hernandez; Stephane Minvielle; Linda M Pilarski; John D Shaughnessy; A Keith Stewart; Hervé Avet-Loiseau
Genetics and cytogenetics of multiple myeloma: a workshop report.
Cancer research 2004;64(4):1546-58.
2003: Bruce R Yacyshyn; Linda M Pilarski
Discussion on the safety of 6-mercaptopurine for childbearing patients with inflammatory bowel disease: a retrospective cohort study.
Gastroenterology 2003;125(5):1562; author reply 1562.
2003: Constantine S Mitsiades; Nicholas Mitsiades; Ron T Bronson; Dharminder Chauhan; Nikhil C Munshi; Steve P Treon; Christopher A Maxwell; Linda M Pilarski; Teru Hideshima; Robert M Hoffman; Kenneth C Anderson
Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications.
Cancer research 2003;63(20):6689-96.
2003: Christopher A Maxwell; Jonathan J Keats; Mary Crainie; Xuejun Sun; Tim Yen; Ellen K Shibuya; Michael Hendzel; Gordon Chan; Linda M Pilarski
RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability.
Molecular biology of the cell 2003;14(6):2262-76.
2003: Christopher Backhouse; Ania Gajdal; Linda M Pilarski; H John Crabtree
Improved resolution with microchip-based enhanced field inversion electrophoresis.
Electrophoresis 2003;24(11):1777-86.
2003: Sophia Adamia; Mary Crainie; Jitra Kriangkum; Michael J Mant; Andrew R Belch; Linda M Pilarski
Abnormal expression of hyaluronan synthases in patients with Waldenstrom's macroglobulimenia.
Seminars in oncology 2003;30(2):165-8.
2003: Jitra Kriangkum; Brian J Taylor; Michael J Mant; Steve P Treon; Andrew R Belch; Linda M Pilarski
The malignant clone in Waldenstrom's macroglobulinemia.
Seminars in oncology 2003;30(2):132-5.
2003: Jonathan J Keats; Tony Reiman; Christopher A Maxwell; Brian J Taylor; Loree Larratt; Michael J Mant; Andrew R Belch; Linda M Pilarski
In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression.
Blood 2003;101(4):1520-9.
2002: Linda M Pilarski; Andrew R Belch
Clonotypic myeloma cells able to xenograft myeloma to nonobese diabetic severe combined immunodeficient mice copurify with CD34 (+) hematopoietic progenitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(10):3198-204.
2002: Linda M Pilarski; Karen Seeberger; Robert W Coupland; Alana Eshpeter; Jonathan J Keats; Brian J Taylor; Andrew R Belch
Leukemic B cells clonally identical to myeloma plasma cells are myelomagenic in NOD/SCID mice.
Experimental hematology 2002;30(3):221-8.
2002: Brian J Taylor; Julie A Pittman; Karen Seeberger; Michael J Mant; Tony Reiman; Andrew R Belch; Linda M Pilarski
Intraclonal homogeneity of clonotypic immunoglobulin M and diversity of nonclinical post-switch isotypes in multiple myeloma: insights into the evolution of the myeloma clone.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):502-13.
2002: Steve P Treon; Linda M Pilarski; Andrew R Belch; Abigail Kelliher; Frederic Preffer; Yoshihito Shima; Constantine S Mitsiades; Nicholas Mitsiades; Agnieszka Szczepek; Leonard Ellman; David Harmon; Michael L Grossbard; Kenneth C Anderson
CD20-directed serotherapy in patients with multiple myeloma: biologic considerations and therapeutic applications.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25(1):72-81.
2001: Tony Reiman; Karen Seeberger; Brian J Taylor; Agnieszka Szczepek; John Hanson; Michael J Mant; Robert W Coupland; Andrew R Belch; Linda M Pilarski
Persistent preswitch clonotypic myeloma cells correlate with decreased survival: evidence for isotype switching within the myeloma clone.
Blood 2001;98(9):2791-9.
2001: Agnieszka Szczepek; Andrew R Belch; Linda M Pilarski
Expression of IL-6 and IL-6 receptors by circulating clonotypic B cells in multiple myeloma: potential for autocrine and paracrine networks.
Experimental hematology 2001;29(9):1076-81.
2000: Steve P Treon; P Maimonis; D Bua; Gloria Young; Noopur Raje; Joseph A Mollick; Dharminder Chauhan; Yu-Tzu Tai; Teru Hideshima; Y Shima; JH Hilgers; Silvia von Mensdorff-Pouilly; Andrew R Belch; Linda M Pilarski; Kenneth C Anderson
Elevated soluble MUC1 levels and decreased anti-MUC1 antibody levels in patients with multiple myeloma.
Blood 2000;96(9):3147-53.
2000: D E Lopes de Menezes; Linda M Pilarski; Andrew R Belch; Theresa M Allen
Selective targeting of immunoliposomal doxorubicin against human multiple myeloma in vitro and ex vivo.
Biochimica et biophysica acta 2000;1466(1-2):205-20.
2000: Linda M Pilarski; N V Giannakopoulos; Agnieszka Szczepek; A M Masellis; Michael J Mant; Andrew R Belch
In multiple myeloma, circulating hyperdiploid B cells have clonotypic immunoglobulin heavy chain rearrangements and may mediate spread of disease.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):585-96.
2000: Linda M Pilarski; G Hipperson; Karen Seeberger; E Pruski; Robert W Coupland; Andrew R Belch
Myeloma progenitors in the blood of patients with aggressive or minimal disease: engraftment and self-renewal of primary human myeloma in the bone marrow of NOD SCID mice.
Blood 2000;95(3):1056-65.
2000: Sheryl L Gares; Linda M Pilarski
Balancing thymocyte adhesion and motility: a functional linkage between beta1 integrins and the motility receptor RHAMM.
Developmental immunology 2000;7(2-4):209-25.
2000: Steve P Treon; Y Shima; Michael L Grossbard; Frederic Preffer; Andrew R Belch; Linda M Pilarski; Kenneth C Anderson
Treatment of multiple myeloma by antibody mediated immunotherapy and induction of myeloma selective antigens.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11 Suppl 1():107-11.
1999: Sheryl L Gares; Linda M Pilarski
Beta1-integrins control spontaneous adhesion and motility of human progenitor thymocytes and regulate differentiation-dependent expression of the receptor for hyaluronan-mediated motility.
Scandinavian journal of immunology 1999;50(6):626-34.
1999: E C LaCasse; Mark R Bray; Bruce Patterson; W M Lim; S Perampalam; LG Radvanyi; Armand Keating; A Keith Stewart; Rena Buckstein; JS Sandhu; N Miller; D Banerjee; D Singh; Andrew R Belch; Linda M Pilarski; Jean Gariépy
Shiga-like toxin-1 receptor on human breast cancer, lymphoma, and myeloma and absence from CD34(+) hematopoietic stem cells: implications for ex vivo tumor purging and autologous stem cell transplantation.
Blood 1999;94(8):2901-10.
1999: Steve P Treon; Y Shima; Frederic Preffer; Deborah Doss; L Ellman; Robert Schlossman; Michael L Grossbard; Andrew R Belch; Linda M Pilarski; Kenneth C Anderson
Treatment of plasma cell dyscrasias by antibody-mediated immunotherapy.
Seminars in oncology 1999;26(5 Suppl 14):97-106.
1999: Linda M Pilarski; E Pruski; Juanita M Wizniak; D Paine; Karen Seeberger; Michael J Mant; C B Brown; Andrew R Belch
Potential role for hyaluronan and the hyaluronan receptor RHAMM in mobilization and trafficking of hematopoietic progenitor cells.
Blood 1999;93(9):2918-27.
1999: Mary Crainie; Andrew R Belch; Michael J Mant; Linda M Pilarski
Overexpression of the receptor for hyaluronan-mediated motility (RHAMM) characterizes the malignant clone in multiple myeloma: identification of three distinct RHAMM variants.
Blood 1999;93(5):1684-96.
1999: Steve P Treon; Joseph A Mollick; Mitsuyoshi Urashima; G Teoh; Dharminder Chauhan; A Ogata; Noopur Raje; JH Hilgers; Lee M Nadler; Andrew R Belch; Linda M Pilarski; Kenneth C Anderson
Muc-1 core protein is expressed on multiple myeloma cells and is induced by dexamethasone.
Blood 1999;93(4):1287-98.
1999: Linda M Pilarski; Michael J Mant; Andrew R Belch
Drug resistance in multiple myeloma: novel therapeutic targets within the malignant clone.
Leukemia & lymphoma 1999;32(3-4):199-210.
1998: Sheryl L Gares; N Giannakopoulos; D MacNeil; R J Faull; Linda M Pilarski
During human thymic development, beta 1 integrins regulate adhesion, motility, and the outcome of RHAMM/hyaluronan engagement.
Journal of leukocyte biology 1998;64(6):781-90.
1998: Agnieszka Szczepek; Karen Seeberger; Juanita M Wizniak; Michael J Mant; Andrew R Belch; Linda M Pilarski
A high frequency of circulating B cells share clonotypic Ig heavy-chain VDJ rearrangements with autologous bone marrow plasma cells in multiple myeloma, as measured by single-cell and in situ reverse transcriptase-polymerase chain reaction.
Blood 1998;92(8):2844-55.
1998: D E Lopes de Menezes; Linda M Pilarski; Theresa M Allen
In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma.
Cancer research 1998;58(15):3320-30.
1998: Linda M Pilarski; Randall W Yatscoff; G F Murphy; Andrew R Belch
Drug resistance in multiple myeloma: cyclosporin A analogues and their metabolites as potential chemosensitizers.
Leukemia 1998;12(4):505-9.
1997: Linda M Pilarski; Agnieszka Szczepek; Andrew R Belch
Deficient drug transporter function of bone marrow-localized and leukemic plasma cells in multiple myeloma.
Blood 1997;90(9):3751-9.
1997: Agnieszka Szczepek; P Leif Bergsagel; L Axelsson; C B Brown; Andrew R Belch; Linda M Pilarski
CD34+ cells in the blood of patients with multiple myeloma express CD19 and IgH mRNA and have patient-specific IgH VDJ gene rearrangements.
Blood 1997;89(5):1824-33.
1997: A Masellis-Smith; Andrew R Belch; Michael J Mant; Linda M Pilarski
Adhesion of multiple myeloma peripheral blood B cells to bone marrow fibroblasts: a requirement for CD44 and alpha4beta7.
Cancer research 1997;57(5):930-6.
1996: Linda M Pilarski; A Masellis-Smith; Agnieszka Szczepek; Michael J Mant; Andrew R Belch
Circulating clonotypic B cells in the biology of multiple myeloma: speculations on the origin of myeloma.
Leukemia & lymphoma 1996;22(5-6):375-83.
1996: Bruce R Yacyshyn; Mary Beth Bowen-Yacyshyn; Linda M Pilarski
Inhibition by rapamycin of P-glycoprotein 170-mediated export from normal lymphocytes.
Scandinavian journal of immunology 1996;43(4):449-55.
1996: A Masellis-Smith; Andrew R Belch; Michael J Mant; E A Turley; Linda M Pilarski
Hyaluronan-dependent motility of B cells and leukemic plasma cells in blood, but not of bone marrow plasma cells, in multiple myeloma: alternate use of receptor for hyaluronan-mediated motility (RHAMM) and CD44.
Blood 1996;87(5):1891-9.
1995: Linda M Pilarski; D Paine; Janet E McElhaney; C E Cass; Andrew R Belch
Multidrug transporter P-glycoprotein 170 as a differentiation antigen on normal human lymphocytes and thymocytes: modulation with differentiation stage and during aging.
American journal of hematology 1995;49(4):323-35.
1995: Linda M Pilarski; Andrew R Belch
Intrinsic expression of the multidrug transporter, P-glycoprotein 170, in multiple myeloma: implications for treatment.
Leukemia & lymphoma 1995;17(5-6):367-74.
1995: Linda M Pilarski; Marian LADEROUTE; D Rutkowski
Apoptosis among CD45RA-/low CD3+ progeny accompanies differentiation of human multinegative thymocytes.
Scandinavian journal of immunology 1995;41(3):237-46.
1995: P Leif Bergsagel; A M Smith; Agnieszka Szczepek; Michael J Mant; Andrew R Belch; Linda M Pilarski
In multiple myeloma, clonotypic B lymphocytes are detectable among CD19+ peripheral blood cells expressing CD38, CD56, and monotypic Ig light chain.
Blood 1995;85(2):436-47.
1995: P Leif Bergsagel; A Masellis Smith; Andrew R Belch; Linda M Pilarski
The blood B-cells and bone marrow plasma cells in patients with multiple myeloma share identical IgH rearrangements.
Current topics in microbiology and immunology 1995;194():17-24.
1994: Marian LADEROUTE; Linda M Pilarski
The inhibition of apoptosis by alpha-fetoprotein (AFP) and the role of AFP receptors in anti-cellular senescence.
Anticancer research 1994;14(6B):2429-38.
1994: J P Deans; Jeffrey A Ledbetter; Linda M Pilarski
Differential modulation of human multinegative (CD3-4-8-) thymocyte proliferation by monoclonal antibodies to CD45RA or to CD45.
Immunology and cell biology 1994;72(4):292-9.
1994: Linda M Pilarski; A Masellis-Smith; Andrew R Belch; B Yang; R C Savani; E A Turley
RHAMM, a receptor for hyaluronan-mediated motility, on normal human lymphocytes, thymocytes and malignant B cells: a mediator in B cell malignancy?
Leukemia & lymphoma 1994;14(5-6):363-74.
1994: Linda M Pilarski; K L Howland; J P Deans
Resistance and susceptibility to cyclosporin A as CD3-4-8- human thymocytes differentiate in vitro.
Scandinavian journal of immunology 1994;39(4):363-72.
1994: Linda M Pilarski; Andrew R Belch
Circulating monoclonal B cells expressing P glycoprotein may be a reservoir of multidrug-resistant disease in multiple myeloma.
Blood 1994;83(3):724-36.
1994: Linda M Pilarski; Bruce R Yacyshyn; A I Lazarovits
Analysis of peripheral blood lymphocyte populations and immune function from children exposed to cyclosporine or to azathioprine in utero.
Transplantation 1994;57(1):133-44.
1993: Bruce R Yacyshyn; Linda M Pilarski
Expression of CD45RO on circulating CD19+ B-cells in Crohn's disease.
Gut 1993;34(12):1698-704.
1993: Linda M Pilarski; J P Deans
CD45 isoform transitions on multinegative human thymocytes differentiating in vitro mimic patterns predicted for selective events in vivo.
Immunology and cell biology 1993;71 ( Pt 4)():289-301.
1993: Linda M Pilarski; H Miszta; E A Turley
Regulated expression of a receptor for hyaluronan-mediated motility on human thymocytes and T cells.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(10):4292-302.
1993: Gitte S Jensen; Andrew R Belch; Michael J Mant; B A Ruether; Bruce R Yacyshyn; Linda M Pilarski
Expression of multiple beta 1 integrins on circulating monoclonal B cells in patients with multiple myeloma.
American journal of hematology 1993;43(1):29-36.
1993: Linda M Pilarski
Adhesive interactions in thymic development: does selective expression of CD45 isoforms promote stage-specific microclustering in the assembly of functional adhesive complexes on differentiating T lineage lymphocytes?
Immunology and cell biology 1993;71 ( Pt 1)():59-69.
1992: Gitte S Jensen; Andrew R Belch; F Kherani; Michael J Mant; B A Ruether; Linda M Pilarski
Restricted expression of immunoglobulin light chain mRNA and of the adhesion molecule CD11b on circulating monoclonal B lineage cells in peripheral blood of myeloma patients.
Scandinavian journal of immunology 1992;36(6):843-53.
1992: Gitte S Jensen; Michael J Mant; Linda M Pilarski
Sequential maturation stages of monoclonal B lineage cells from blood, spleen, lymph node, and bone marrow from a terminal myeloma patient.
American journal of hematology 1992;41(3):199-208.
1992: Linda M Pilarski; Gitte S Jensen
Monoclonal circulating B cells in multiple myeloma. A continuously differentiating, possibly invasive, population as defined by expression of CD45 isoforms and adhesion molecules.
Hematology/oncology clinics of North America 1992;6(2):297-322.
1992: J P Deans; H M Serra; J Shaw; YJ Shen; R M Torres; Linda M Pilarski
Transient accumulation and subsequent rapid loss of messenger RNA encoding high molecular mass CD45 isoforms after T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(6):1898-905.
1992: Linda M Pilarski; C E Cass; T Tsuro; Andrew R Belch
Multidrug resistance of a continuously differentiating monoclonal B lineage in the blood and bone marrow of patients with multiple myeloma.
Current topics in microbiology and immunology 1992;182():177-85.
1992: Gitte S Jensen; Andrew R Belch; Michael J Mant; B A Ruether; Linda M Pilarski
Expression of multiple adhesion molecules on circulating monoclonal B cells in myeloma.
Current topics in microbiology and immunology 1992;182():187-93.
1991: J P Deans; John A Wilkins; S Caixia; E Pruski; Linda M Pilarski
Prolonged expression of high molecular mass CD45RA isoform during the differentiation of human progenitor thymocytes to CD3+ cells in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4060-8.
1991: Linda M Pilarski; Bruce R Yacyshyn; Gitte S Jensen; E Pruski; Henry F Pabst
Beta 1 integrin (CD29) expression on human postnatal T cell subsets defined by selective CD45 isoform expression.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(3):830-7.
1991: Gitte S Jensen; Michael J Mant; A J Belch; J R Berenson; B A Ruether; Linda M Pilarski
Selective expression of CD45 isoforms defines CALLA+ monoclonal B-lineage cells in peripheral blood from myeloma patients as late stage B cells.
Blood 1991;78(3):711-9.
1991: Linda M Pilarski; E A Turley; Andrew R E Shaw; W M Gallatin; M P Laderoute; R Gillitzer; I G Beckman; H Zola
FMC46, a cell protrusion-associated leukocyte adhesion molecule-1 epitope on human lymphocytes and thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(1):136-43.
1991: Gitte S Jensen; E J Andrews; Michael J Mant; R Vergidis; Jeffrey A Ledbetter; Linda M Pilarski
Transitions in CD45 isoform expression indicate continuous differentiation of a monoclonal CD5+ CD11b+ B lineage in Waldenstrom's macroglobulinemia.
American journal of hematology 1991;37(1):20-30.
1990: M Egerton; E Pruski; Linda M Pilarski
Cell generation within human thymic subsets defined by selective expression of CD45 (T200) isoforms.
Human immunology 1990;27(4):333-47.
1989: J P Deans; J Shaw; M J Pearse; Linda M Pilarski
CD45R as a primary signal transducer stimulating IL-2 and IL-2R mRNA synthesis by CD3-4-8- thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(8):2425-30.
1989: J P Deans; A W Boyd; Linda M Pilarski
Transitions from high to low molecular weight isoforms of CD45 (T200) involve rapid activation of alternate mRNA splicing and slow turnover of surface CD45R.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(4):1233-8.
1989: Linda M Pilarski; J P Deans
Selective expression of CD45 isoforms and of maturation antigens during human thymocyte differentiation: observations and hypothesis.
Immunology letters 1989;21(3):187-98.
1989: Linda M Pilarski; R Gillitzer; H Zola; K Shortman; Roland Scollay
Definition of the thymic generative lineage by selective expression of high molecular weight isoforms of CD45 (T200).
European journal of immunology 1989;19(4):589-97.
1989: Linda M Pilarski; E J Andrews; H M Serra; B A Ruether; Michael J Mant
Comparative analysis of immunodeficiency in patients with monoclonal gammopathy of undetermined significance and patients with untreated multiple myeloma.
Scandinavian journal of immunology 1989;29(2):217-28.
1989: Linda M Pilarski; E J Andrews; H M Serra; Jeffrey A Ledbetter; B A Ruether; Michael J Mant
Abnormalities in lymphocyte profile and specificity repertoire of patients with Waldenstrom's macroglobulinemia, multiple myeloma, and IgM monoclonal gammopathy of undetermined significance.
American journal of hematology 1989;30(2):53-60.
1989: Gitte S Jensen; S Poppema; Michael J Mant; Linda M Pilarski
Transition in CD45 isoform expression during differentiation of normal and abnormal B cells.
International immunology 1989;1(3):229-36.
1988: K Kelly; Linda M Pilarski; Ken Shortman; Roland Scollay
CD4+ CD8+ cells are rare among in vitro activated mouse or human T lymphocytes.
Cellular immunology 1988;117(2):414-24.
1988: H M Serra; Jeffrey A Ledbetter; D Neil; Linda M Pilarski
Apparent loss of 2H4+ T cells in peripheral blood lymphocytes of normal donors: a 2H4-specific artefact unique to T cells.
Human immunology 1988;23(4):281-8.
1988: H M Serra; Michael J Mant; B A Ruether; Jeffrey A Ledbetter; Linda M Pilarski
Selective loss of CD4+ CD45R+ T cells in peripheral blood of multiple myeloma patients.
Journal of clinical immunology 1988;8(4):259-65.
1988: H M Serra; J F Krowka; Jeffrey A Ledbetter; Linda M Pilarski
Loss of CD45R (Lp220) represents a post-thymic T cell differentiation event.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1435-41.
1988: Linda M Pilarski; J F Krowka; J P Deans
Soluble antigen-specific helper molecules active in the induction of cytotoxic T lymphocytes.
Annals of the New York Academy of Sciences 1988;532():136-48.
1987: Anna Janowska-Wieczorek; E J Andrews; A Khaliq; Linda M Pilarski
Deficiency of mature B and T lymphocyte subsets in the blood of non-Hodgkin lymphoma patients.
American journal of hematology 1987;26(2):125-34.
1987: J P Deans; J F Krowka; TR Mosmann; Linda M Pilarski
Antigen-specific helper factor reacts with antibody to the T-cell receptor.
Journal of immunogenetics 1987;14(2-3):103-7.
1986: Linda M Pilarski; E J Andrews; Michael J Mant; B A Ruether
Humoral immune deficiency in multiple myeloma patients due to compromised B-cell function.
Journal of clinical immunology 1986;6(6):491-501.
1986: J F Krowka; Bhagirath Singh; A Fotedar; TR Mosmann; M A Giedlin; Linda M Pilarski
A requirement for physical linkage between determinants recognized by helper molecules and cytotoxic T cell precursors in the induction of cytotoxic T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(10):3561-6.
1985: Linda M Pilarski; Michael J Mant; B A Ruether; G Carayanniotis; D Otto; J F Krowka
Abnormal clonogenic potential of T cells from multiple myeloma patients.
Blood 1985;66(6):1266-71.
1985: Linda M Pilarski; Michael J Mant; B A Ruether
Pre-B cells in peripheral blood of multiple myeloma patients.
Blood 1985;66(2):416-22.
1985: Linda M Pilarski; M Piotrowska-Krezolak; D J Gibney; L Winger; C Winger; Michael J Mant; B A Ruether
Specificity repertoire of lymphocytes from multiple myeloma patients. I. High frequency of B cells specific for idiotypic and F(ab')2-region determinants on immunoglobulin.
Journal of clinical immunology 1985;5(4):275-84.
1985: Linda M Pilarski; B A Ruether; Michael J Mant
Abnormal function of B lymphocytes from peripheral blood of multiple myeloma patients. Lack of correlation between the number of cells potentially able to secrete immunoglobulin M and serum immunoglobulin M levels.
The Journal of clinical investigation 1985;75(6):2024-9.
1984: Linda M Pilarski; Michael J Mant; B A Ruether; A Belch
Severe deficiency of B lymphocytes in peripheral blood from multiple myeloma patients.
The Journal of clinical investigation 1984;74(4):1301-6.