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Carol Pilbeam
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Research Profile (preview)
Living Beings
Anatomy
Chemicals & Drugs
Physiology
Phenomena
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Network (preview)
51
Raisz, Lawrence
16
Alander, Cynthia
16
Kawaguchi, Hiroshi
10
Voznesensky, Olga
9
Choudhary, Shilpa
6
Herschman, Harvey
6
Li, Xiaodong
5
Mehrotra, Meenal
5
Prestwood, Karen
4
Wadhwa, Sunil
4
Lorenzo, Joseph
4
Kenny, Anne
4
Klein-Nulend, Jenneke
4
Harrison, John
3
Chikazu, Daichi
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Publications
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Geonetwork of Carol Pilbeam (preview)
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All Publications
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2008: Choudhary Shilpa; Huang Hechang; Raisz Lawrence; Pilbeam Carol
Anabolic effects of PTH in cyclooxygenase-2 knockout osteoblasts in vitro.
Biochemical and biophysical research communications 2008;372(4):536-41.
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2008: Taylor John A; Pilbeam Carol; Nisbet Andrew
Role of the prostaglandin pathway and the use of NSAIDs in genitourinary malignancies.
Expert review of anticancer therapy 2008;8(7):1125-34.
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2008: Choudhary Shilpa; Alander Cynthia; Zhan Peili; Gao Qi; Pilbeam Carol; Raisz Lawrence
Effect of deletion of the prostaglandin EP2 receptor on the anabolic response to prostaglandin E2 and a selective EP2 receptor agonist.
Prostaglandins & other lipid mediators 2008;86(1-4):35-40.
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2007: Kaneko H; Mehrotra M; Alander C; Lerner U; Pilbeam C; Raisz L
Effects of prostaglandin E2 and lipopolysaccharide on osteoclastogenesis in RAW 264.7 cells.
Prostaglandins, leukotrienes, and essential fatty acids 2007;77(3-4):181-6.
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2007: Xu Zheng; Choudhary Shilpa; Okada Yosuke; Voznesensky Olga; Alander Cynthia; Raisz Lawrence; Pilbeam Carol
Cyclooxygenase-2 gene disruption promotes proliferation of murine calvarial osteoblasts in vitro.
Bone 2007;41(1):68-76.
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2007: Choudhary Shilpa; Halbout Philippe; Alander Cynthia; Raisz Lawrence; Pilbeam Carol
Strontium ranelate promotes osteoblastic differentiation and mineralization of murine bone marrow stromal cells: involvement of prostaglandins.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(7):1002-10.
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2007: Taylor John A; Kuchel George A; Hegde Poornima; Voznesensky Olga S; Claffey Kevin; Tsimikas John; Leng Lin; Bucala Richard; Pilbeam Carol
Null mutation for macrophage migration inhibitory factor (MIF) is associated with less aggressive bladder cancer in mice.
BMC cancer 2007;7():135.
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2006: Taylor John A; Zhu Qing; Irwin Brian; Maghaydah Yazeed; Tsimikas John; Pilbeam Carol; Leng Lin; Bucala Richard; Kuchel George A
Null mutation in macrophage migration inhibitory factor prevents muscle cell loss and fibrosis in partial bladder outlet obstruction.
American journal of physiology. Renal physiology 2006;291(6):F1343-53.
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2006: Mehrotra Meenal; Saegusa Masatomo; Wadhwa Sunil; Voznesensky Olga; Peterson Donald; Pilbeam Carol
Fluid flow induces Rankl expression in primary murine calvarial osteoblasts.
Journal of cellular biochemistry 2006;98(5):1271-83.
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2006: Xu Zheng; Choudhary Shilpa; Voznesensky Olga; Mehrotra Meenal; Woodard Monica; Hansen Marc; Herschman Harvey; Pilbeam Carol
Overexpression of COX-2 in human osteosarcoma cells decreases proliferation and increases apoptosis.
Cancer research 2006;66(13):6657-64.
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2006: Mehrotra Meenal; Saegusa Masatomo; Voznesensky Olga; Pilbeam Carol
Role of Cbfa1/Runx2 in the fluid shear stress induction of COX-2 in osteoblasts.
Biochemical and biophysical research communications 2006;341(4):1225-30.
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2005: Zhan Peili; Alander Cynthia; Kaneko Hironori; Pilbeam Carol C; Guan Youfei; Zhang Yahua; Breyer Matthew D; Raisz Lawrence G
Effect of deletion of the prostaglandin EP4 receptor on stimulation of calcium release from cultured mouse calvariae: impaired responsiveness in heterozygotes.
Prostaglandins & other lipid mediators 2005;78(1-4):19-26.
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2005: Chikazu Daichi; Li Xiaodong; Kawaguchi Hiroshi; Sakuma Yoko; Voznesensky Olga S; Adams Douglas J; Xu Manshan; Hoshi Kazuto; Katavic Vedran; Herschman Harvey R; Raisz Lawrence G; Pilbeam Carol C
Bone morphogenetic protein 2 induces cyclo-oxygenase 2 in osteoblasts via a Cbfa1 binding site: role in effects of bone morphogenetic protein 2 in vitro and in vivo. 2002.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(10):1888-98.
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2005: Xu Manshan; Choudhary Shilpa; Goltzman David; Ledgard Felicia; Adams Douglas; Gronowicz Gloria; Koczon-Jaremko Boguslawa; Raisz Lawrence; Pilbeam Carol
Do cyclooxygenase-2 knockout mice have primary hyperparathyroidism?
Endocrinology 2005;146(4):1843-53.
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2005: Ono Katsuhiro; Kaneko Hironori; Choudhary Shilpa; Pilbeam Carol C; Lorenzo Joseph A; Akatsu Takuhiko; Kugai Nobuo; Raisz Lawrence G
Biphasic effect of prostaglandin E2 on osteoclast formation in spleen cell cultures: role of the EP2 receptor.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(1):23-9.
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2004: Mehrotra Meenal; Krane Stephen M; Walters Kristen; Pilbeam Carol
Differential regulation of platelet-derived growth factor stimulated migration and proliferation in osteoblastic cells.
Journal of cellular biochemistry 2004;93(4):741-52.
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2004: Choudhary Shilpa; Kumar Ashok; Kale Raosaheb K; Raisz Lawrence G; Pilbeam Carol C
Extracellular calcium induces COX-2 in osteoblasts via a PKA pathway.
Biochemical and biophysical research communications 2004;322(2):395-402.
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2004: Sakuma Yoko; Li Ziaodong; Pilbeam Carol C; Alander Cynthia B; Chikazu Daichi; Kawaguchi Hiroshi; Raisz Lawrence G
Stimulation of cAMP production and cyclooxygenase-2 by prostaglandin E(2) and selective prostaglandin receptor agonists in murine osteoblastic cells.
Bone 2004;34(5):827-34.
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2003: Ono Katsuhiro; Akatsu Takuhiko; Kugai Nobuo; Pilbeam Carol C; Raisz Lawrence G
The effect of deletion of cyclooxygenase-2, prostaglandin receptor EP2, or EP4 in bone marrow cells on osteoclasts induced by mouse mammary cancer cell lines.
Bone 2003;33(5):798-804.
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2003: Choudhary Shilpa; Wadhwa Sunil; Raisz Lawrence G; Alander Cynthia; Pilbeam Carol C
Extracellular calcium is a potent inducer of cyclo-oxygenase-2 in murine osteoblasts through an ERK signaling pathway.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(10):1813-24.
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2003: Okada Yosuke; Pilbeam Carol; Raisz Lawrence; Tanaka Yoshiya
Role of cyclooxygenase-2 in bone resorption.
Journal of UOEH 2003;25(2):185-95.
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2002: Wadhwa Sunil; Choudhary Shilpa; Voznesensky Maria; Epstein Mary; Raisz Lawrence; Pilbeam Carol
Fluid flow induces COX-2 expression in MC3T3-E1 osteoblasts via a PKA signaling pathway.
Biochemical and biophysical research communications 2002;297(1):46-51.
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2002: Okada Yosuke; Morimoto Isao; Ura Kazumi; Watanabe Kenichi; Eto Sumiya; Kumegawa Masayoshi; Raisz Lawrence; Pilbeam Carol; Tanaka Yoshiya
Cell-to-Cell adhesion via intercellular adhesion molecule-1 and leukocyte function-associated antigen-1 pathway is involved in 1alpha,25(OH)2D3, PTH and IL-1alpha-induced osteoclast differentiation and bone resorption.
Endocrine journal 2002;49(4):483-95.
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2002: Chikazu Daichi; Li Xiaodong; Kawaguchi Hiroshi; Sakuma Yoko; Voznesensky Olga S; Adams Douglas J; Xu Manshan; Hoshio Kazuto; Katavic Vedran; Herschman Harvey R; Raisz Lawrence G; Pilbeam Carol C
Bone morphogenetic protein 2 induces cyclo-oxygenase 2 in osteoblasts via a Cbfal binding site: role in effects of bone morphogenetic protein 2 in vitro and in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(8):1430-40.
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2002: Li Xiaodong; Tomita Masato; Pilbeam Carol C; Breyer Richard M; Raisz Lawrence G
Prostaglandin receptor EP2 mediates PGE2 stimulated hypercalcemia in mice in vivo.
Prostaglandins & other lipid mediators 2002;67(3-4):173-80.
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2002: Li X; Pilbeam C C; Pan L; Breyer R M; Raisz L G
Effects of prostaglandin E2 on gene expression in primary osteoblastic cells from prostaglandin receptor knockout mice.
Bone 2002;30(4):567-73.
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2002: Sobue T; Gravely T; Hand A; Min Y K; Pilbeam C; Raisz L G; Zhang X; Larocca D; Florkiewicz R; Hurley M M
Regulation of fibroblast growth factor 2 and fibroblast growth factor receptors by transforming growth factor beta in human osteoblastic MG-63 cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(3):502-12.
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2002: Wadhwa Sunil; Godwin Stephen L; Peterson Donald R; Epstein Mary A; Raisz Lawrence G; Pilbeam Carol C
Fluid flow induction of cyclo-oxygenase 2 gene expression in osteoblasts is dependent on an extracellular signal-regulated kinase signaling pathway.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(2):266-74.
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2002: Tomita M; Li X; Okada Y; Woodiel F N; Young R N; Pilbeam C C; Raisz L G
Effects of selective prostaglandin EP4 receptor antagonist on osteoclast formation and bone resorption in vitro.
Bone 2002;30(1):159-63.
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2000: Li X; Okada Y; Pilbeam C C; Lorenzo J A; Kennedy C R; Breyer R M; Raisz L G
Knockout of the murine prostaglandin EP2 receptor impairs osteoclastogenesis in vitro.
Endocrinology 2000;141(6):2054-61.
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2000: Okada Y; Voznesensky O; Herschman H; Harrison J; Pilbeam C
Identification of multiple cis-acting elements mediating the induction of prostaglandin G/H synthase-2 by phorbol ester in murine osteoblastic cells.
Journal of cellular biochemistry 2000;78(2):197-209.
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2000: Okada Y; Lorenzo J A; Freeman A M; Tomita M; Morham S G; Raisz L G; Pilbeam C C
Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture.
The Journal of clinical investigation 2000;105(6):823-32.
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1999: Prestwood K M; Thompson D L; Kenny A M; Seibel M J; Pilbeam C C; Raisz L G
Low dose estrogen and calcium have an additive effect on bone resorption in older women.
The Journal of clinical endocrinology and metabolism 1999;84(1):179-83.
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1998: Min Y K; Rao Y; Okada Y; Raisz L G; Pilbeam C C
Regulation of prostaglandin G/H synthase-2 expression by interleukin-1 in human osteoblast-like cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(7):1066-75.
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1998: Lorenzo J A; Naprta A; Rao Y; Alander C; Glaccum M; Widmer M; Gronowicz G; Kalinowski J; Pilbeam C C
Mice lacking the type I interleukin-1 receptor do not lose bone mass after ovariectomy.
Endocrinology 1998;139(6):3022-5.
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1997: Pilbeam C; Rao Y; Voznesensky O; Kawaguchi H; Alander C; Raisz L; Herschman H
Transforming growth factor-beta1 regulation of prostaglandin G/H synthase-2 expression in osteoblastic MC3T3-E1 cells.
Endocrinology 1997;138(11):4672-82.
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1997: Nemoto K; Pilbeam C C; Bilak S R; Raisz L G
Molecular cloning and expression of a rat prostaglandin E2 receptor of the EP2 subtype.
Prostaglandins 1997;54(4):713-25.
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1997: Tetradis S; Pilbeam C C; Liu Y; Herschman H R; Kream B E
Parathyroid hormone increases prostaglandin G/H synthase-2 transcription by a cyclic adenosine 3',5'-monophosphate-mediated pathway in murine osteoblastic MC3T3-E1 cells.
Endocrinology 1997;138(9):3594-600.
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1997: Pilbeam C C; Fall P M; Alander C B; Raisz L G
Differential effects of nonsteroidal anti-inflammatory drugs on constitutive and inducible prostaglandin G/H synthase in cultured bone cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(8):1198-203.
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1997: Tai H; Miyaura C; Pilbeam C C; Tamura T; Ohsugi Y; Koishihara Y; Kubodera N; Kawaguchi H; Raisz L G; Suda T
Transcriptional induction of cyclooxygenase-2 in osteoblasts is involved in interleukin-6-induced osteoclast formation.
Endocrinology 1997;138(6):2372-9.
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1997: Klein-Nulend J; Burger E H; Semeins C M; Raisz L G; Pilbeam C C
Pulsating fluid flow stimulates prostaglandin release and inducible prostaglandin G/H synthase mRNA expression in primary mouse bone cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(1):45-51.
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1997: Pilbeam C C; Kawaguchi H; Voznesensky O S; Alander C B; Raisz L G
Regulation of inducible prostaglandin G/H synthase by interleukin-1, transforming growth factors-alpha and -beta, and prostaglandins in bone cells.
Advances in experimental medicine and biology 1997;400B():617-23.
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1996: Vargas S J; Naprta A; Lee S K; Kalinowski J; Kawaguchi H; Pilbeam C C; Raisz L G; Lorenzo J A
Lack of evidence for an increase in interleukin-6 expression in adult murine bone, bone marrow, and marrow stromal cell cultures after ovariectomy.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(12):1926-34.
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1996: Tetradis S; Pilbeam C C; Liu Y; Kream B E
Parathyroid hormone induces prostaglandin G/H synthase-2 expression by a cyclic adenosine 3',5'-monophosphate-mediated pathway in the murine osteoblastic cell line MC3T3-E1.
Endocrinology 1996;137(12):5435-40.
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1996: Kawaguchi H; Nemoto K; Raisz L G; Harrison J R; Voznesensky O S; Alander C B; Pilbeam C C
Interleukin-4 inhibits prostaglandin G/H synthase-2 and cytosolic phospholipase A2 induction in neonatal mouse parietal bone cultures.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(3):358-66.
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1996: Hakeda Y; Kawaguchi H; Hurley M; Pilbeam C C; Abreu C; Linkhart T A; Mohan S; Kumegawa M; Raisz L G
Intact insulin-like growth factor binding protein-5 (IGFBP-5) associates with bone matrix and the soluble fragments of IGFBP-5 accumulated in culture medium of neonatal mouse calvariae by parathyroid hormone and prostaglandin E2-treatment.
Journal of cellular physiology 1996;166(2):370-9.
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1996: Prestwood K M; Pannullo A M; Kenny A M; Pilbeam C C; Raisz L G
The effect of a short course of calcium and vitamin D on bone turnover in older women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1996;6(4):314-9.
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1995: Nemoto K; Bernecker P M; Pilbeam C C; Raisz L G
Expression and regulation of prostaglandin F receptor mRNA in rodent osteoblastic cells.
Prostaglandins 1995;50(5-6):349-58.
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1995: Kenny A M; Prestwood K M; Pilbeam C C; Raisz L G
The short term effects of tamoxifen on bone turnover in older women.
The Journal of clinical endocrinology and metabolism 1995;80(11):3287-91.
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1995: Kawaguchi H; Pilbeam C C; Gronowicz G; Abreu C; Fletcher B S; Herschman H R; Raisz L G; Hurley M M
Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor.
The Journal of clinical investigation 1995;96(2):923-30.
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1995: Kawaguchi H; Pilbeam C C; Vargas S J; Morse E E; Lorenzo J A; Raisz L G
Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae.
The Journal of clinical investigation 1995;96(1):539-48.
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1995: Kenny A M; MacGillivray D C; Pilbeam C C; Crombie H D; Raisz L G
Fracture incidence in postmenopausal women with primary hyperparathyroidism.
Surgery 1995;118(1):109-14.
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1995: Kawaguchi H; Pilbeam C C; Harrison J R; Raisz L G
The role of prostaglandins in the regulation of bone metabolism.
Clinical orthopaedics and related research 1995;(313):36-46.
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1995: Pilbeam C C; Raisz L G; Voznesensky O; Alander C B; Delman B N; Kawaguchi H
Autoregulation of inducible prostaglandin G/H synthase in osteoblastic cells by prostaglandins.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(3):406-14.
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1995: Prestwood K M; Pilbeam C C; Raisz L G
Treatment of osteoporosis.
Annual review of medicine 1995;46():249-56.
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1994: Kawaguchi H; Raisz L G; Voznesensky O S; Alander C B; Hakeda Y; Pilbeam C C
Regulation of the two prostaglandin G/H synthases by parathyroid hormone, interleukin-1, cortisol, and prostaglandin E2 in cultured neonatal mouse calvariae.
Endocrinology 1994;135(3):1157-64.
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1994: Kawaguchi H; Pilbeam C C; Raisz L G
Anabolic effects of 3,3',5-triiodothyronine and triiodothyroacetic acid in cultured neonatal mouse parietal bones.
Endocrinology 1994;135(3):971-6.
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1994: Prestwood K M; Pilbeam C C; Burleson J A; Woodiel F N; Delmas P D; Deftos L J; Raisz L G
The short-term effects of conjugated estrogen on bone turnover in older women.
The Journal of clinical endocrinology and metabolism 1994;79(2):366-71.
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1994: Kawaguchi H; Yavari R; Stover M L; Rowe D W; Raisz L G; Pilbeam C C
Measurement of interleukin-1 stimulated constitutive prostaglandin G/H synthase (cyclooxygenase) mRNA levels in osteoblastic MC3T3-E1 cells using competitive reverse transcriptase polymerase chain reaction.
Endocrine research 1994;20(3):219-33.
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1994: Harrison J R; Lorenzo J A; Kawaguchi H; Raisz L G; Pilbeam C
Stimulation of prostaglandin E2 production by interleukin-1 alpha and transforming growth factor alpha in osteoblastic MC3T3-E1 cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(6):817-23.
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1994: Kawaguchi H; Pilbeam C C; Woodiel F N; Raisz L G
Comparison of the effects of 3,5,3'-triiodothyroacetic acid and triiodothyronine on bone resorption in cultured fetal rat long bones and neonatal mouse calvariae.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(2):247-53.
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1993: Pilbeam C C; Kawaguchi H; Hakeda Y; Voznesensky O; Alander C B; Raisz L G
Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic MC3T3-E1 cells.
The Journal of biological chemistry 1993;268(34):25643-9.
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1993: Pilbeam C C; Alander C B; Simmons H A; Raisz L G
Comparison of the effects of various lengths of synthetic human parathyroid hormone-related peptide (hPTHrP) of malignancy on bone resorption and formation in organ culture.
Bone 1993;14(5):717-20.
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1993: Raisz L G; Pilbeam C C; Fall P M
Prostaglandins: mechanisms of action and regulation of production in bone.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1993;3 Suppl 1():136-40.
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1992: Lorenzo J A; Pilbeam C C; Kalinowski J F; Hibbs M S
Production of both 92- and 72-kDa gelatinases by bone cells.
Matrix (Stuttgart, Germany) 1992;12(4):282-90.
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1991: Klein-Nulend J; Pilbeam C C; Raisz L G
Effect of 1,25-dihydroxyvitamin D3 on prostaglandin E2 production in cultured mouse parietal bones.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(12):1339-44.
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1991: Klein-Nulend J; Pilbeam C C; Harrison J R; Fall P M; Raisz L G
Mechanism of regulation of prostaglandin production by parathyroid hormone, interleukin-1, and cortisol in cultured mouse parietal bones.
Endocrinology 1991;128(5):2503-10.
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1990: Pilbeam C C; Raisz L G
Effects of androgens on parathyroid hormone and interleukin-1-stimulated prostaglandin production in cultured neonatal mouse calvariae.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(11):1183-8.
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1989: Pilbeam C C; Klein-Nulend J; Raisz L G
Inhibition by 17 beta-estradiol of PTH stimulated resorption and prostaglandin production in cultured neonatal mouse calvariae.
Biochemical and biophysical research communications 1989;163(3):1319-24.
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