Leonor Pinilla

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Roa J; Garcia-Galiano D; Varela L; Sánchez-Garrido M A; Pineda R; Castellano J M; Ruiz-Pino F; Romero M; Aguilar E; López M; Gaytan F; Diéguez C; Pinilla L; Tena-Sempere M
The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system.
Gutiérrez-Pascual Ester; Leprince Jérôme; Martínez-Fuentes Antonio J; Ségalas-Milazzo Isabelle; Pineda Rafael; Roa Juan; Duran-Prado Mario; Guilhaudis Laure; Desperrois Elia; Lebreton Aurélie; Pinilla Leonor; Tonon Marie-Christine; Malagón María M; Vaudry Hubert; Tena-Sempere Manuel; Castaño Justo P
In vivo and in vitro structure-activity relationships and structural conformation of Kisspeptin-10-related peptides.
Navarro V M; Sánchez-Garrido M A; Castellano J M; Roa J; García-Galiano D; Pineda R; Aguilar E; Pinilla L; Tena-Sempere M
Persistent impairment of hypothalamic KiSS-1 system after exposures to estrogenic compounds at critical periods of brain sex differentiation.

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All Publications

2009: Roa J; Garcia-Galiano D; Varela L; Sánchez-Garrido M A; Pineda R; Castellano J M; Ruiz-Pino F; Romero M; Aguilar E; López M; Gaytan F; Diéguez C; Pinilla L; Tena-Sempere M
The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system.
Endocrinology 2009;150(11):5016-26.
2009: Gutiérrez-Pascual Ester; Leprince Jérôme; Martínez-Fuentes Antonio J; Ségalas-Milazzo Isabelle; Pineda Rafael; Roa Juan; Duran-Prado Mario; Guilhaudis Laure; Desperrois Elia; Lebreton Aurélie; Pinilla Leonor; Tonon Marie-Christine; Malagón María M; Vaudry Hubert; Tena-Sempere Manuel; Castaño Justo P
In vivo and in vitro structure-activity relationships and structural conformation of Kisspeptin-10-related peptides.
Molecular pharmacology 2009;76(1):58-67.
2009: Navarro V M; Sánchez-Garrido M A; Castellano J M; Roa J; García-Galiano D; Pineda R; Aguilar E; Pinilla L; Tena-Sempere M
Persistent impairment of hypothalamic KiSS-1 system after exposures to estrogenic compounds at critical periods of brain sex differentiation.
Endocrinology 2009;150(5):2359-67.
2009: Castellano J M; Navarro V M; Roa J; Pineda R; Sánchez-Garrido M A; García-Galiano D; Vigo E; Dieguez C; Aguilar E; Pinilla L; Tena-Sempere M
Alterations in hypothalamic KiSS-1 system in experimental diabetes: early changes and functional consequences.
Endocrinology 2009;150(2):784-94.
2009: Roa J; Castellano J M; Navarro V M; Handelsman D J; Pinilla L; Tena-Sempere M
Kisspeptins and the control of gonadotropin secretion in male and female rodents.
Peptides 2009;30(1):57-66.
2009: Castellano J M; Roa J; Luque R M; Dieguez C; Aguilar E; Pinilla L; Tena-Sempere M
KiSS-1/kisspeptins and the metabolic control of reproduction: physiologic roles and putative physiopathological implications.
Peptides 2009;30(1):139-45.
2008: Roa J; Vigo E; Castellano J M; Gaytan F; García-Galiano D; Navarro V M; Aguilar E; Dijcks F A; Ederveen A G H; Pinilla L; van Noort P I; Tena-Sempere M
Follicle-stimulating hormone responses to kisspeptin in the female rat at the preovulatory period: modulation by estrogen and progesterone receptors.
Endocrinology 2008;149(11):5783-90.
2008: Caminos J E; Nogueiras R; Gaytán F; Pineda R; González C R; Barreiro M L; Castaño J P; Malagón M M; Pinilla L; Toppari J; Diéguez C; Tena-Sempere M
Novel expression and direct effects of adiponectin in the rat testis.
Endocrinology 2008;149(7):3390-402.
2008: Roa J; Vigo E; Castellano J M; Gaytan F; Navarro V M; Aguilar E; Dijcks F A; Ederveen A G H; Pinilla L; van Noort P I; Tena-Sempere M
Opposite roles of estrogen receptor (ER)-alpha and ERbeta in the modulation of luteinizing hormone responses to kisspeptin in the female rat: implications for the generation of the preovulatory surge.
Endocrinology 2008;149(4):1627-37.
2008: Roa Juan; Aguilar Enrique; Dieguez Carlos; Pinilla Leonor; Tena-Sempere Manuel
New frontiers in kisspeptin/GPR54 physiology as fundamental gatekeepers of reproductive function.
Frontiers in neuroendocrinology 2008;29(1):48-69.
2007: Pinilla L; Fernández-Fernández R; Roa J; Castellano J M; Tena-Sempere M; Aguilar E
Selective role of neuropeptide Y receptor subtype Y2 in the control of gonadotropin secretion in the rat.
American journal of physiology. Endocrinology and metabolism 2007;293(5):E1385-92.
2007: Vigo Eva; Roa Juan; Pineda Rafael; Castellano Juan M; Navarro Victor M; Aguilar Enrique; Pinilla Leonor; Tena-Sempere Manuel
Novel role of the anorexigenic peptide neuromedin U in the control of LH secretion and its regulation by gonadal hormones and photoperiod.
American journal of physiology. Endocrinology and metabolism 2007;293(5):E1265-73.
2007: Gutiérrez-Pascual E; Martínez-Fuentes A J; Pinilla L; Tena-Sempere M; Malagón M M; Castaño J P
Direct pituitary effects of kisspeptin: activation of gonadotrophs and somatotrophs and stimulation of luteinising hormone and growth hormone secretion.
Journal of neuroendocrinology 2007;19(7):521-30.
2007: Fernández-Fernández Rafael; Tena-Sempere Manuel; Roa Juan; Castellano Juan Manuel; Navarro Víctor M; Aguilar Enrique; Pinilla Leonor
Direct stimulatory effect of ghrelin on pituitary release of LH through a nitric oxide-dependent mechanism that is modulated by estrogen.
Reproduction (Cambridge, England) 2007;133(6):1223-32.
2007: Vigo E; Roa J; López M; Castellano J M; Fernandez-Fernandez R; Navarro V M; Pineda R; Aguilar E; Diéguez C; Pinilla L; Tena-Sempere M
Neuromedin s as novel putative regulator of luteinizing hormone secretion.
Endocrinology 2007;148(2):813-23.
2007: Rodriguez-Pacheco Francisca; Martinez-Fuentes Antonio J; Tovar Sulay; Pinilla Leonor; Tena-Sempere Manuel; Dieguez Carlos; Castaño Justo P; Malagon María M
Regulation of pituitary cell function by adiponectin.
Endocrinology 2007;148(1):401-10.
2006: Castellano J M; Navarro V M; Fernández-Fernández R; Roa J; Vigo E; Pineda R; Steiner R A; Aguilar E; Pinilla L; Tena-Sempere M
Effects of galanin-like peptide on luteinizing hormone secretion in the rat: sexually dimorphic responses and enhanced sensitivity at male puberty.
American journal of physiology. Endocrinology and metabolism 2006;291(6):E1281-9.
2006: Davies J S; Thompson N M; Christian H C; Pinilla L; Ebling F J P; Tena-Sempere M; Wells T
Hypothalamic expression of human growth hormone induces post-pubertal hypergonadotrophism in male transgenic growth retarded rats.
Journal of neuroendocrinology 2006;18(10):719-31.
2006: Castellano J M; Gaytan M; Roa J; Vigo E; Navarro V M; Bellido C; Dieguez C; Aguilar E; Sánchez-Criado J E; Pellicer A; Pinilla L; Gaytan F; Tena-Sempere M
Expression of KiSS-1 in rat ovary: putative local regulator of ovulation?
Endocrinology 2006;147(10):4852-62.
2006: Castellano Juan M; Navarro Victor M; Fernández-Fernández Rafael; Roa Juan; Vigo Eva; Pineda Rafael; Dieguez Carlos; Aguilar Enrique; Pinilla Leonor; Tena-Sempere Manuel
Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats.
Diabetes 2006;55(9):2602-10.
2006: Castellano J M; Navarro V M; Fernández-Fernández R; Castaño J P; Malagón M M; Aguilar E; Dieguez C; Magni P; Pinilla L; Tena-Sempere M
Ontogeny and mechanisms of action for the stimulatory effect of kisspeptin on gonadotropin-releasing hormone system of the rat.
Molecular and cellular endocrinology 2006;257-258():75-83.
2006: Fernandez-Fernandez R; Martini A C; Navarro V M; Castellano J M; Dieguez C; Aguilar E; Pinilla L; Tena-Sempere M
Novel signals for the integration of energy balance and reproduction.
Molecular and cellular endocrinology 2006;254-255():127-32.
2006: Roa J; Vigo E; Castellano J M; Navarro V M; Fernández-Fernández R; Casanueva F F; Dieguez C; Aguilar E; Pinilla L; Tena-Sempere M
Hypothalamic expression of KiSS-1 system and gonadotropin-releasing effects of kisspeptin in different reproductive states of the female Rat.
Endocrinology 2006;147(6):2864-78.
2006: Tovar S; Vázquez M J; Navarro V M; Fernández-Fernández R; Castellano J M; Vigo E; Roa J; Casanueva F F; Aguilar E; Pinilla L; Dieguez C; Tena-Sempere M
Effects of single or repeated intravenous administration of kisspeptin upon dynamic LH secretion in conscious male rats.
Endocrinology 2006;147(6):2696-704.
2006: Pinilla L; Fernández-Fernández R; Vigo E; Navarro V M; Roa J; Castellano J M; Pineda R; Tena-Sempere M; Aguilar E
Stimulatory effect of PYY-(3-36) on gonadotropin secretion is potentiated in fasted rats.
American journal of physiology. Endocrinology and metabolism 2006;290(6):E1162-71.
2006: Navarro V M; Fernández-Fernández R; Nogueiras R; Vigo E; Tovar S; Chartrel N; Le Marec O; Leprince J; Aguilar E; Pinilla L; Dieguez C; Vaudry H; Tena-Sempere M
Novel role of 26RFa, a hypothalamic RFamide orexigenic peptide, as putative regulator of the gonadotropic axis.
The Journal of physiology 2006;573(Pt 1):237-49.
2006: Martini A C; Fernández-Fernández R; Tovar S; Navarro V M; Vigo E; Vazquez M J; Davies J S; Thompson N M; Aguilar E; Pinilla L; Wells T; Dieguez C; Tena-Sempere M
Comparative analysis of the effects of ghrelin and unacylated ghrelin on luteinizing hormone secretion in male rats.
Endocrinology 2006;147(5):2374-82.
2006: Leffers H; Navarro V M; Nielsen John E; Mayen A; Pinilla L; Dalgaard M; Malagon M M; Castaño J P; Skakkebaek N E; Aguilar E; Tena-Sempere M
Increased expression of alpha- and beta-globin mRNAs at the pituitary following exposure to estrogen during the critical period of neonatal sex differentiation in the rat.
The Journal of steroid biochemistry and molecular biology 2006;99(1):33-43.
2005: Aguilar Enrique; Tena-Sempere Manuel; Pinilla Leonor
Role of excitatory amino acids in the control of growth hormone secretion.
Endocrine 2005;28(3):295-302.
2005: Barreiro M L; Pineda R; Gaytan F; Archanco M; Burrell M A; Castellano J M; Hakovirta H; Nurmio M; Pinilla L; Aguilar E; Toppari J; Dieguez C; Tena-Sempere M
Pattern of orexin expression and direct biological actions of orexin-a in rat testis.
Endocrinology 2005;146(12):5164-75.
2005: Castellano J M; Navarro V M; Fernández-Fernández R; Nogueiras R; Tovar S; Roa J; Vazquez M J; Vigo E; Casanueva F F; Aguilar E; Pinilla L; Dieguez C; Tena-Sempere M
Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition.
Endocrinology 2005;146(9):3917-25.
2005: Fernández-Fernández R; Navarro V M; Barreiro M L; Vigo E M; Tovar S; Sirotkin A V; Casanueva F F; Aguilar E; Dieguez C; Pinilla L; Tena-Sempere M
Effects of chronic hyperghrelinemia on puberty onset and pregnancy outcome in the rat.
Endocrinology 2005;146(7):3018-25.
2005: Navarro V M; Castellano J M; Fernández-Fernández R; Tovar S; Roa J; Mayen A; Barreiro M L; Casanueva F F; Aguilar E; Dieguez C; Pinilla L; Tena-Sempere M
Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat.
Endocrinology 2005;146(4):1689-97.
2005: Fernandez-Fernandez R; Aguilar E; Tena-Sempere M; Pinilla L
Effects of polypeptide YY(3-36) upon luteinizing hormone-releasing hormone and gonadotropin secretion in prepubertal rats: in vivo and in vitro studies.
Endocrinology 2005;146(3):1403-10.
2005: Navarro V M; Castellano J M; Fernández-Fernández R; Tovar S; Roa J; Mayen A; Nogueiras R; Vazquez M J; Barreiro M L; Magni P; Aguilar E; Dieguez C; Pinilla L; Tena-Sempere M
Characterization of the potent luteinizing hormone-releasing activity of KiSS-1 peptide, the natural ligand of GPR54.
Endocrinology 2005;146(1):156-63.
2005: Fernández-Fernández Rafael; Tena-Sempere Manuel; Navarro Víctor M; Barreiro María L; Castellano Juan M; Aguilar Enrique; Pinilla Leonor
Effects of ghrelin upon gonadotropin-releasing hormone and gonadotropin secretion in adult female rats: in vivo and in vitro studies.
Neuroendocrinology 2005;82(5-6):245-55.
2004: Navarro V M; Fernández-Fernández R; Castellano J M; Roa J; Mayen A; Barreiro M L; Gaytan F; Aguilar E; Pinilla L; Dieguez C; Tena-Sempere M
Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54.
The Journal of physiology 2004;561(Pt 2):379-86.
2004: Navarro V M; Castellano J M; Fernández-Fernández R; Barreiro M L; Roa J; Sanchez-Criado J E; Aguilar E; Dieguez C; Pinilla L; Tena-Sempere M
Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide.
Endocrinology 2004;145(10):4565-74.
2004: Aguilar E; Fernandez-Fernandez R; Tena-Sempere M; Pinilla L
Effects of peptide YY(3-36) on PRL secretion: pituitary and extra-pituitary actions in the rat.
Peptides 2004;25(7):1147-52.
2004: Fernández-Fernández Rafael; Tena-Sempere Manuel; Aguilar Enrique; Pinilla Leonor
Ghrelin effects on gonadotropin secretion in male and female rats.
Neuroscience letters 2004;362(2):103-7.
2004: Barreiro M L; Pineda R; Navarro V M; Lopez M; Suominen J S; Pinilla L; Señaris R; Toppari J; Aguilar E; Diéguez C; Tena-Sempere M
Orexin 1 receptor messenger ribonucleic acid expression and stimulation of testosterone secretion by orexin-A in rat testis.
Endocrinology 2004;145(5):2297-306.
2004: Tena-Sempere Manuel; Aguilar Enrique; Fernandez-Fernandez Rafael; Pinilla Leonor
Ghrelin inhibits prolactin secretion in prepubertal rats.
Neuroendocrinology 2004;79(3):133-41.
2004: Tena-Sempere M; Barreiro M L; Aguilar E; Pinilla L
Mechanisms for altered reproductive function in female rats following neonatal administration of raloxifene.
European journal of endocrinology / European Federation of Endocrine Societies 2004;150(3):397-403.
2004: Gaytan F; Barreiro M L; Caminos J E; Chopin L K; Herington A C; Morales C; Pinilla L; Paniagua R; Nistal M; Casanueva F F; Aguilar E; Diéguez C; Tena-Sempere M
Expression of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in normal human testis and testicular tumors.
The Journal of clinical endocrinology and metabolism 2004;89(1):400-9.
2003: Barreiro M L; Suominen J S; Gaytán F; Pinilla L; Chopin L K; Casanueva F F; Diéguez C; Aguilar E; Toppari J; Tena-Sempere M
Developmental, stage-specific, and hormonally regulated expression of growth hormone secretagogue receptor messenger RNA in rat testis.
Biology of reproduction 2003;68(5):1631-40.
2003: Pinilla Leonor; Barreiro M Luz; Tena-Sempere Manuel; Aguilar Enrique
Role of ghrelin in the control of growth hormone secretion in prepubertal rats: interactions with excitatory amino acids.
Neuroendocrinology 2003;77(2):83-90.
2003: Gaytan F; Barreiro M L; Chopin L K; Herington A C; Morales C; Pinilla L; Casanueva F F; Aguilar E; Diéguez C; Tena-Sempere M
Immunolocalization of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in the cyclic human ovary.
The Journal of clinical endocrinology and metabolism 2003;88(2):879-87.
2003: Pinilla Leonor; Gonzalez Lucas C; Tena-Sempere Manuel; Aguilar Enrique
5-HT1 and 5-HT2 receptor activation reduces N-methyl-D-aspartate (NMDA)-stimulated LH secretion in prepubertal male and female rats.
European journal of endocrinology / European Federation of Endocrine Societies 2003;148(1):121-7.
2002: Barreiro M L; Gaytán F; Caminos J E; Pinilla L; Casanueva F F; Aguilar E; Diéguez C; Tena-Sempere M
Cellular location and hormonal regulation of ghrelin expression in rat testis.
Biology of reproduction 2002;67(6):1768-76.
2002: Barreiro M L; Pinilla L; Aguilar E; Tena-Sempere M
Expression and homologous regulation of GH secretagogue receptor mRNA in rat adrenal gland.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(5):677-88.
2002: Pinilla L; Barreiro M L; Tena-Sempere M; Aguilar E
Raloxifene effects upon the neuronal system controlling sexual receptivity in female rats.
Neuroscience letters 2002;329(3):285-8.
2002: Pinilla L; Barreiro M L; Gonzalez L C; Tena-Sempere M; Aguilar E
Comparative effects of testosterone propionate, oestradiol benzoate, ICI 182,780, tamoxifen and raloxifene on hypothalamic differentiation in the female rat.
The Journal of endocrinology 2002;172(3):441-8.
2002: Pinilla L; González L C; Tena-Sempere M; Aguilar E
Interactions between GABAergic and aminoacidergic pathways in the control of gonadotropin and GH secretion in pre-pubertal female rats.
Journal of endocrinological investigation 2002;25(2):96-100.
2002: Tena-Sempere M; Barreiro M L; González L C; Gaytán F; Zhang F-P; Caminos J E; Pinilla L; Casanueva F F; Diéguez C; Aguilar E
Novel expression and functional role of ghrelin in rat testis.
Endocrinology 2002;143(2):717-25.
2001: Tena-Sempere M; Barreiro M L; González L C; Pinilla L; Aguilar E
Differential neonatal imprinting and regulation by estrogen of estrogen receptor subtypes alpha and beta and of the truncated estrogen receptor product (TERP-1) mRNA expression in the male rat pituitary.
Neuroendocrinology 2001;74(5):347-58.
2001: Pinilla L; Gonzalez L C; Tena-Sempere M; Aguilar E
Evidence for an estrogen-like action of raloxifene upon the hypothalamic-pituitary unit: raloxifene inhibits luteinizing hormone secretion and stimulates prolactin secretion in ovariectomized female rats.
Neuroscience letters 2001;311(3):149-52.
2001: Pinilla L; González L C; Tena-Sempere M; Aguilar E
Interactions between serotoninergic and aminoacidergic pathways in the control of PRL secretion in prepubertal male rats.
Journal of physiology and biochemistry 2001;57(3):237-44.
2001: Tena-Sempere M; Manna P R; Zhang F P; Pinilla L; González L C; Diéguez C; Huhtaniemi I; Aguilar E
Molecular mechanisms of leptin action in adult rat testis: potential targets for leptin-induced inhibition of steroidogenesis and pattern of leptin receptor messenger ribonucleic acid expression.
The Journal of endocrinology 2001;170(2):413-23.
2001: Pinilla L; González L C; Gaytán F; Tena-Sempere M; Aguilar E
Oestrogenic effects of neonatal administration of raloxifene on hypothalamic-pituitary-gonadal axis in male and female rats.
Reproduction (Cambridge, England) 2001;121(6):915-24.
2001: Pinilla L; Gonzalez L C; Tena-Sempere M; Aguilar E
5-HT1 and 5-HT2 receptor agonists blunt +/- -alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-stimulated GH secretion in prepubertal male rats.
European journal of endocrinology / European Federation of Endocrine Societies 2001;144(5):535-41.
2001: Tena-Sempere M; Pinilla L; Zhang F P; González L C; Huhtaniemi I; Casanueva F F; Dieguez C; Aguilar E
Developmental and hormonal regulation of leptin receptor (Ob-R) messenger ribonucleic acid expression in rat testis.
Biology of reproduction 2001;64(2):634-43.
2001: Pinilla L; Gonzalez L C; Tena-Sempere M; Aguilar E
Cross-talk between excitatory and inhibitory amino acids in the regulation of growth hormone secretion in neonatal rats.
Neuroendocrinology 2001;73(1):62-7.
2001: Tena-Sempere M; González L C; Pinilla L; Huhtaniemi I; Aguilar E
Neonatal imprinting and regulation of estrogen receptor alpha and beta mRNA expression by estrogen in the pituitary and hypothalamus of the male rat.
Neuroendocrinology 2001;73(1):12-25.
2001: Pinilla L; González L C; Tena-Sempere M; Bellido C; Aguilar E
Effects of systemic blockade of nitric oxide synthases on pulsatile LH, prolactin, and GH secretion in adult male rats.
Hormone research 2001;55(5):229-35.
2000: Pinilla L; Gonzalez L; Tena-Sempere M; Aguilar E
Activation of AMPA receptors inhibits prolactin and estradiol secretion and delays the onset of puberty in female rats.
The Journal of steroid biochemistry and molecular biology 2000;75(4-5):277-81.
2000: Tena-Sempere M; Pinilla L; González L C; Casanueva F F; Diéguez C; Aguilar E
Homologous and heterologous down-regulation of leptin receptor messenger ribonucleic acid in rat adrenal gland.
The Journal of endocrinology 2000;167(3):479-86.
2000: González L C; Pinilla L; Tena-Sempere M; Aguilar E
Regulation of prolactin secretion by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in male rats.
The Journal of endocrinology 2000;166(3):669-75.
2000: Tena-Sempere M; Navarro J; Pinilla L; González L C; Huhtaniemi I; Aguilar E
Neonatal exposure to estrogen differentially alters estrogen receptor alpha and beta mRNA expression in rat testis during postnatal development.
The Journal of endocrinology 2000;165(2):345-57.
2000: Tena-Sempere M; Pinilla L; González L C; Navarro J; Diéguez C; Casanueva F F; Aguilar E
In vitro pituitary and testicular effects of the leptin-related synthetic peptide leptin(116-130) amide involve actions both similar to and distinct from those of the native leptin molecule in the adult rat.
European journal of endocrinology / European Federation of Endocrine Societies 2000;142(4):406-10.
2000: Gonzalez L C; Pinilla L; Tena-Sempere M; Dieguez C; Casanueva F F; Aguilar E
Effect of acute immunoneutralization of endogenous leptin on prolactin and LH secretion during the afternoon of pro-oestrus or in steroid-treated ovariectomized female rats.
Journal of reproduction and fertility 2000;118(1):39-45.
2000: Tena-Sempere M; Pinilla L; González L C; Aguilar E
Regulation of growth hormone (GH) secretion by different glutamate receptor subtypes in the rat.
Amino acids 2000;18(1):1-16.
1999: Gonzalez L C; Pinilla L; Tena-Sempere M; Aguilar E
Leptin(116-130) stimulates prolactin and luteinizing hormone secretion in fasted adult male rats.
Neuroendocrinology 1999;70(3):213-20.
1999: González L C; Pinilla L; Tena-Sempere M; Aguilar E
Role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in the control of prolactin, growth hormone and gonadotropin secretion in prepubertal rats.
The Journal of endocrinology 1999;162(3):417-24.
1999: Pinilla L; Tena-Sempere M; Gonzalez D; Aguilar E
The role of nitric oxide in the control of basal and LHRH-stimulated LH secretion.
Journal of endocrinological investigation 1999;22(5):340-8.
1999: Tena-Sempere M; Pinilla L; González L C; Diéguez C; Casanueva F F; Aguilar E
Leptin inhibits testosterone secretion from adult rat testis in vitro.
The Journal of endocrinology 1999;161(2):211-8.
1999: Pinilla L; Seoane L M; Gonzalez L; Carro E; Aguilar E; Casanueva F F; Dieguez C
Regulation of serum leptin levels by gonadal function in rats.
European journal of endocrinology / European Federation of Endocrine Societies 1999;140(5):468-73.
1999: González L C; Pinilla L; Tena-Sempere M; Aguilar E
Regulation of growth hormone secretion by alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in infantile, prepubertal, and adult male rats.
Endocrinology 1999;140(3):1279-84.
1999: Pinilla L; Gonzalez L; Tena-Sempere M; Dieguez C; Aguilar E
Gonadal and age-related influences on NMDA-induced growth hormone secretion in male rats.
Neuroendocrinology 1999;69(1):11-9.
1999: Pinilla L; Tena-Sempere M; Aguilar E
Nitric oxide stimulates growth hormone secretion in vitro through a calcium- and cyclic guanosine monophosphate-independent mechanism.
Hormone research 1999;51(5):242-7.
1998: Pinilla L; González L C; Tena-Sempere M; Aguilar E
Nitro(w)-arginine methyl ester treatment delayed the onset of puberty in female rats.
Journal of physiology and biochemistry 1998;54(3):135-9.
1998: Pinilla L; González D; Tena-Sempere M; Aguilar E
Nitric oxide (NO) stimulates gonadotropin secretion in vitro through a calcium-dependent, cGMP-independent mechanism.
Neuroendocrinology 1998;68(3):180-6.
1998: Pinilla L; Tena-Sempere M; Aguilar E
Sexual differences in the role of kainate receptors in controlling gonadotrophin secretion in prepubertal rats.
Journal of reproduction and fertility 1998;113(2):269-73.
1998: Pinilla L; Tena-Sempere M; Aguilar E
Role of excitatory amino acid pathways in control of gonadotrophin secretion in adult female rats sterilized by neonatal administration of oestradiol or testosterone.
Journal of reproduction and fertility 1998;113(1):53-9.
1998: Pinilla L; Tena-Sempere M; Aguilar R; Aguilar E
Effects of N-methyl-D-aspartic acid and kainic acid on prolactin secretion in hyper- and hypoprolactinaemic conditions.
European journal of endocrinology / European Federation of Endocrine Societies 1998;138(4):460-6.
1997: Carro E; Pinilla L; Seoane L M; Considine R V; Aguilar E; Casanueva F F; Dieguez C
Influence of endogenous leptin tone on the estrous cycle and luteinizing hormone pulsatility in female rats.
Neuroendocrinology 1997;66(6):375-7.
1997: Pinilla L; Tena-Sempere M; Aguilar E
Role of serotoninergic receptors in gonadotropin secretion in male rats.
Journal of endocrinological investigation 1997;20(7):410-6.
1997: Aguilar E; Tena-Sempere M; Aguilar R; González D; Pinilla L
Interactions between N-methyl-D-aspartate, nitric oxide and serotonin in the control of prolactin secretion in prepubertal male rats.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(1):99-106.
1996: Pinilla L; Gonzalez D; Tena-Sempere M; Aguilar R; Aguilar E
Mechanisms of inhibitory action of kainic acid on prolactin secretion in male rats.
The Journal of endocrinology 1996;151(1):159-67.
1996: Pinilla L; González D; Tena-Sempere M; Aguilar R; Aguilar E
Effects of N-methyl-D-aspartate and kainic acid on prolactin secretion in prepubertal female rats.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(4):464-8.
1996: Tena-Sempere M; Pinilla L; Aguilar E
The pattern of testosterone replacement influences the recovery of the stimulatory effect of clonidine on growth hormone (GH) secretion in orchidectomized rats.
The Journal of steroid biochemistry and molecular biology 1996;58(5-6):533-8.
1996: Tena-Sempere M; Pinilla L; González D; Aguilar E
Involvement of endogneous nitric oxide in the control of pituitary responsiveness to different elicitors of growth hormone release in prepubertal rats.
Neuroendocrinology 1996;64(2):146-52.
1996: Pinilla L; Tena-Sempere M; Gonzalez D; Aguilar E
Positive role of non-N-methyl-D-aspartate receptors in the control of growth hormone secretion in male rats.
Journal of endocrinological investigation 1996;19(6):353-8.
1996: Aguilar E; Tena-Sempere M; Gonzalez D; Pinilla L
Control of gonadotropin secretion in prepubertal male rats by excitatory amino acids.
Andrologia 1996;28(3):163-9.
1996: Tena-Sempere M; Pinilla L; Aguilar E
In vitro pituitary GH secretion after GHRH, forskolin, dibutyryl cyclic-adenosine 3',5'-monophosphate and phorbol 12-myristate 13-acetate stimulation in long-term orchidectomized rats.
Journal of molecular endocrinology 1996;16(1):81-8.
1995: Pinilla L; Tena-Sempere M; Aguilar E
The role of excitatory amino acid pathways in the control of pituitary function in neonatally oestrogenized male rats.
The Journal of endocrinology 1995;147(1):51-7.
1995: Pinilla L; Tena-Sempere M; Gonzalez D; Aguilar E
Mechanisms of altered LH secretion in neonatally oestrogenized male rats.
The Journal of endocrinology 1995;147(1):43-50.
1995: Tena-Sempere M; Pinilla L; Aguilar E
Orchidectomy selectively increases follicle-stimulating hormone secretion in gonadotropin-releasing hormone antagonist-treated male rats.
European journal of endocrinology / European Federation of Endocrine Societies 1995;132(3):357-62.
1994: Aguilar E; Ranchal A; Tena-Sempere M; Pinilla L
Serotoninergic control of prolactin secretion in prepubertal male rats.
European journal of endocrinology / European Federation of Endocrine Societies 1994;131(5):547-54.
1994: Gaytan F; Pinilla L; Romero J L; Aguilar E
Differential effects of the administration of human chorionic gonadotropin to postnatal rats.
The Journal of endocrinology 1994;142(3):527-34.
1994: Pinilla L; Garnelo P; Tena-Sempere M; Gaytan F; Aguilar E
Mechanisms of reproductive deficiency in male rats treated neonatally with a gonadotrophin-releasing hormone antagonist.
The Journal of endocrinology 1994;142(3):517-25.
1994: Pinilla L; Ranchal A; Aguilar R; Aguilar E
Role of the serotonergic system in the control of gonadotropin secretion in prepubertal male rats.
European journal of endocrinology / European Federation of Endocrine Societies 1994;130(6):617-24.
1993: Tena-Sempere M; Pinilla L; Aguilar E
Follicle-stimulating hormone and luteinizing hormone secretion in male rats orchidectomized or injected with ethylene dimethane sulfonate.
Endocrinology 1993;133(3):1173-81.
1993: Trimiño E; Pinilla L; Aguilar E
Pituitary-gonadal function in neonatal and adult female rats treated with gonadotropin-releasing hormone agonist and antagonist: short- and long-term effects.
Acta endocrinologica 1993;129(3):251-9.
1993: Pinilla L; Trimiño E; Garnelo P; Bellido C; Aguilar R; Gaytán F; Aguilar E
Changes in pituitary secretion during the early postnatal period and anovulatory syndrome induced by neonatal oestrogen or androgen in rats.
Journal of reproduction and fertility 1993;97(1):13-20.
1993: Aguilar E; Pinilla L; Tena-Sempere M
Growth hormone-releasing hormone-induced growth hormone secretion in adult rats orchidectomized or injected with ethylene dimethane sulphonate.
Neuroendocrinology 1993;57(1):132-4.
1993: Aguilar E; Ranchal A; Aguilar R; Pinilla L
Gonadotropin and prolactin secretion in prepubertal female rats treated with 8-hydroxy-2-(di-n-propylamino) tetralin.
Journal of neural transmission. General section 1993;94(3):165-73.
1992: Gaytan F; Aceitero J; Lucena C; Aguilar E; Pinilla L; Garnelo P; Bellido C
Simultaneous proliferation and differentiation of mast cells and Leydig cells in the rat testis. Are common regulatory factors involved?
Journal of andrology 1992;13(5):387-97.
1992: Pinilla L; Garnelo P; Gaytan F; Aguilar E
Hypothalamic-pituitary function in neonatally oestrogen-treated male rats.
The Journal of endocrinology 1992;134(2):279-86.
1992: Garnelo P; Pinilla L; Gaytan F; Aguilar E
Pituitary-testis function in rats treated neonatally with a gonadotrophin-releasing hormone agonist: short- and long-term effects.
The Journal of endocrinology 1992;134(2):269-77.
1992: Aguilar E; Rodriguez Padilla M L; Bellido C; Tena-Sempere M; Pinilla L
Changes in follicle-stimulating hormone secretion in spontaneously hypertensive rats.
Neuroendocrinology 1992;56(1):85-93.
1992: Aguilar E; Tena-Sempere M; Pinilla L
5-alpha androstane diol stimulates the pituitary growth hormone responsiveness to growth hormone releasing hormone more effectively than testosterone or dihydrotestosterone in rats.
Acta endocrinologica 1992;126(2):162-6.
1992: Pinilla L; Rodriguez-Padilla M L; Sanchez-Criado J; Gaytan F; Aguilar E
Mechanism of reproductive deficiency in spontaneously hypertensive rats.
Physiology & behavior 1992;51(1):99-104.
1991: Aguilar E; Pinilla L
Ovarian role in the modulation of pituitary responsiveness to growth hormone-releasing hormone in rats.
Neuroendocrinology 1991;54(3):286-90.
1990: Gaytán F; Aceitero J; Bellido C; Pinilla L; Aguilar R; Aguilar E
Are eosinophil leucocytes involved in the oestrogenic response of the postnatal rat epididymis?
International journal of andrology 1990;13(6):500-7.
1990: Bellido C; Pinilla L; Aguilar R; Gaytan F; Aguilar E
Possible role of changes in post-natal gonadotrophin concentrations on permanent impairment of the reproductive system in neonatally oestrogenized male rats.
Journal of reproduction and fertility 1990;90(2):369-74.
1990: Aguilar E; Rodríguez M L; Bellido C; de la Fuente M; Pinilla L
Changes in growth hormone secretion in spontaneously hypertensive rats.
Neuroendocrinology 1990;52(4):337-41.
1990: Aguilar E; Rodríguez-Padilla M L; Pinilla L
Normoprolactinaemia in spontaneously hypertensive rats: absence of a close relationship between plasma concentrations of prolactin and systolic blood pressure.
The Journal of endocrinology 1990;125(3):359-64.
1990: Pinilla L; López F J; Aguilar E
The effect of orchidectomy on rat pituitary responsiveness to GHRH depends on age.
Acta endocrinologica 1990;122(3):349-53.
1989: Pinilla L; López F; González D; Fernández-Galaz C; Sánchez Criado J E; Aguilar E
Luteinizing-hormone-mediated precocious puberty induced in female rats by a prepuberal pituitary graft.
Neuroendocrinology 1989;50(5):495-9.
1989: Gaytan F; Carrera G; Pinilla L; Aguilar R; Bellido C
Mast cells in the testis, epididymis and accessory glands of the rat: effects of neonatal steroid treatment.
Journal of andrology 1989;10(5):351-8.
1987: Aguilar E; Bellido C; Aguilar R; Pinilla L; Tejero A; Galaz C F
Mechanisms in the production of prepuberal reproductive defects in neonatal estrogenized male rats.
Andrologia 1987;19(1):22-31.
1986: Gaytan F; Pinilla L; Aguilar R; Lucena M C; Paniagua R
Effects of neonatal estrogen administration on rat testis development with particular reference to Sertoli cells.
Journal of andrology 1986;7(2):112-21.
1985: Sánchez-Criado J E; Mediavilla M D; Pinilla L; Guisado R
Different olfactory system deficits affect the antigonadal action of light deprivation differently in male rats.
Revista española de fisiología 1985;41(4):395-9.
1984: Aguilar E; Pinilla L; Guisado R; González D; López F
Relation between body weight, growth rate, chronological age and puberty in male and female rats.
Revista española de fisiología 1984;40(1):83-6.

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