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Ronit Pinkas-Kramarski

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Eran Schmukler; Sari Schokoroy; Eya Wolfson; Adva Amir; Efrat Grinboim; Yoel Kloog; Ronit Pinkas-Kramarski
Ras inhibition enhances autophagy, which partially protects cells from death.
Eran Schmukler; Ben Shai; Marcelo Ehrlich; Ronit Pinkas-Kramarski
Neuregulin promotes incomplete autophagy of prostate cancer cells that is independent of mTOR pathway inhibition.
Keren Farin; Sari Schokoroy; Roni Haklai; Ifat Cohen-Or; Galit Elad-Sfadia; Merit E Reyes-Reyes; Paula J Bates; Adrienne D Cox; Yoel Kloog; Ronit Pinkas-Kramarski
Oncogenic synergism between ErbB1, nucleolin, and mutant Ras.

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All Publications

2013: Eran Schmukler; Sari Schokoroy; Eya Wolfson; Adva Amir; Efrat Grinboim; Yoel Kloog; Ronit Pinkas-Kramarski
Ras inhibition enhances autophagy, which partially protects cells from death.
Oncotarget 2013;4(1):145-55.
2012: Eran Schmukler; Ben Shai; Marcelo Ehrlich; Ronit Pinkas-Kramarski
Neuregulin promotes incomplete autophagy of prostate cancer cells that is independent of mTOR pathway inhibition.
PloS one 2012;7(5):e36828.
2011: Keren Farin; Sari Schokoroy; Roni Haklai; Ifat Cohen-Or; Galit Elad-Sfadia; Merit E Reyes-Reyes; Paula J Bates; Adrienne D Cox; Yoel Kloog; Ronit Pinkas-Kramarski
Oncogenic synergism between ErbB1, nucleolin, and mutant Ras.
Cancer research 2011;71(6):2140-51.
2010: Shelly Adi-Harel; Shlomit Erlich; Eran Schmukler; Sarit Cohen-Kedar; Oshik Segev; Liat Mizrachy; Joel A Hirsch; Ronit Pinkas-Kramarski
Beclin 1 self-association is independent of autophagy induction by amino acid deprivation and rapamycin treatment.
Journal of cellular biochemistry 2010;110(5):1262-71.
2009: Einat Zalckvar; Hanna Berissi; Liat Mizrachy; Yulia Idelchuk; Itay Koren; Miriam Eisenstein; Helena Sabanay; Ronit Pinkas-Kramarski; Adi Kimchi
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy.
EMBO reports 2009;10(3):285-92.
2009: Keren Farin; Ayelet Di-Segni; Adam Mor; Ronit Pinkas-Kramarski
Structure-function analysis of nucleolin and ErbB receptors interactions.
PloS one 2009;4(7):e6128.
2008: Ayelet Di-Segni; Keren Farin; Ronit Pinkas-Kramarski
Identification of nucleolin as new ErbB receptors- interacting protein.
PloS one 2008;3(6):e2310.
2007: Shlomit Erlich; Liat Mizrachy; Oshik Segev; Liora Lindenboim; Ofir Zmira; Sheli Adi-Harel; Joel A Hirsch; Reuven Stein; Ronit Pinkas-Kramarski
Differential interactions between Beclin 1 and Bcl-2 family members.
Autophagy 2007;3(6):561-8.
2007: Shlomit Erlich; Alexander Alexandrovich; Esther Shohami; Ronit Pinkas-Kramarski
Rapamycin is a neuroprotective treatment for traumatic brain injury.
Neurobiology of disease 2007;26(1):86-93.
2006: Pazit Tal-Or; Shlomit Erlich; Natalie Porat-Shliom; Yona Goldshmit; Gilad Ben-Baruch; Ezra Shaharabani; Yoel Kloog; Ronit Pinkas-Kramarski
Ligand-independent regulation of ErbB4 receptor phosphorylation by activated Ras.
Journal of cellular biochemistry 2006;98(6):1482-94.
2006: Shlomit Erlich; Pazit Tal-Or; Ronit Liebling; Roy Blum; Devarajan Karunagaran; Yoel Kloog; Ronit Pinkas-Kramarski
Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells.
Biochemical pharmacology 2006;72(4):427-36.
2006: Gilad Silberberg; Saurav Guha; Ronit Pinkas-Kramarski; Ruth Navon
The involvement of ErbB4 with schizophrenia: association and expression studies.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006;141B(2):142-8.
2006: Ayelet Di-Segni; Keren Farin; Ronit Pinkas-Kramarski
ErbB4 activation inhibits MPP+-induced cell death in PC12-ErbB4 cells: involvement of PI3K and Erk signaling.
Journal of molecular neuroscience : MN 2006;29(3):257-67.
2006: Shlomit Erlich; Esther Shohami; Ronit Pinkas-Kramarski
Neurodegeneration induces upregulation of Beclin 1.
Autophagy 2006;2(1):49-51.
2005: Tal Diskin; Pazit Tal-Or; Shlomit Erlich; Liat Mizrachy; Alexander Alexandrovich; Esther Shohami; Ronit Pinkas-Kramarski
Closed head injury induces upregulation of Beclin 1 at the cortical site of injury.
Journal of neurotrauma 2005;22(7):750-62.
2005: Bose S Kochupurakkal; Daniel Harari; Ayelet Di-Segni; Galia Maik-Rachline; Ljuba Lyass; Gal Gur; Gabriele Kerber; Ami Citri; Sara Lavi; Raya Eilam; Vered Chalifa-Caspi; Zelig Eshhar; Eli Pikarsky; Ronit Pinkas-Kramarski; Sarah S Bacus; Yosef Yarden
Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity.
The Journal of biological chemistry 2005;280(9):8503-12.
2005: Ayelet Di-Segni; Ezra Shaharabani; Reuven Stein; Ronit Pinkas-Kramarski
Neuregulins rescue PC12-ErbB-4 cells from cell death induced by beta-amyloid peptide: involvement of PI3K and PKC.
Journal of molecular neuroscience : MN 2005;26(1):57-69.
2003: Pazit Tal-Or; Ayelet Di-Segni; Zippora Lupowitz; Ronit Pinkas-Kramarski
Neuregulin promotes autophagic cell death of prostate cancer cells.
The Prostate 2003;55(2):147-57.
2001: Yona Goldshmit; Shlomit Erlich; Ronit Pinkas-Kramarski
Neuregulin rescues PC12-ErbB4 cells from cell death induced by H(2)O(2). Regulation of reactive oxygen species levels by phosphatidylinositol 3-kinase.
The Journal of biological chemistry 2001;276(49):46379-85.
2001: Y Goldsmit; Shlomit Erlich; Ronit Pinkas-Kramarski
Neuregulin induces sustained reactive oxygen species generation to mediate neuronal differentiation.
Cellular and molecular neurobiology 2001;21(6):753-69.
2001: Shlomit Erlich; Yona Goldshmit; Zippora Lupowitz; Ronit Pinkas-Kramarski
ErbB-4 activation inhibits apoptosis in PC12 cells.
Neuroscience 2001;107(2):353-62.
2000: Shlomit Erlich; Esther Shohami; Ronit Pinkas-Kramarski
Closed head injury induces up-regulation of ErbB-4 receptor at the site of injury.
Molecular and cellular neurosciences 2000;16(5):597-608.
2000: A Vaskovsky; Zippora Lupowitz; Shlomit Erlich; Ronit Pinkas-Kramarski
ErbB-4 activation promotes neurite outgrowth in PC12 cells.
Journal of neurochemistry 2000;74(3):979-87.
1998: E Tzahar; JD Moyer; Hadassa Waterman; E Gabriella Barbacci; Jing Bao; Gil Levkowitz; Maya Shelly; S Strano; Ronit Pinkas-Kramarski; JH Pierce; glenn andrews; Yosef Yarden
Pathogenic poxviruses reveal viral strategies to exploit the ErbB signaling network.
The EMBO journal 1998;17(20):5948-63.
1998: Ronit Pinkas-Kramarski; Maya Shelly; B C Guarino; Ling Mei Wang; Ljuba Lyass; Iris Alroy; M Alimandi; A Kuo; JD Moyer; Sara Lavi; Miriam Eisenstein; BJ Ratzkin; Rony Seger; Sarah S Bacus; JH Pierce; glenn andrews; Yosef Yarden; M Alamandi
ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.
Molecular and cellular biology 1998;18(10):6090-101.
1998: Lenferink Anne; Ronit Pinkas-Kramarski; Monique L M van De Poll; MJ van Vugt; LN Klapper; E Tzahar; Hadassa Waterman; Michael Sela; Everardus J J van Zoelen; Yosef Yarden
Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers.
The EMBO journal 1998;17(12):3385-97.
1998: Maya Shelly; Ronit Pinkas-Kramarski; B C Guarino; Hadassa Waterman; Ling Mei Wang; Ljuba Lyass; M Alimandi; A Kuo; Sarah S Bacus; JH Pierce; glenn andrews; Yosef Yarden
Epiregulin is a potent pan-ErbB ligand that preferentially activates heterodimeric receptor complexes.
The Journal of biological chemistry 1998;273(17):10496-505.
1998: Ronit Pinkas-Kramarski; Lenferink Anne; Sarah S Bacus; Ljuba Lyass; Monique L M van De Poll; LN Klapper; E Tzahar; Michael Sela; Everardus J J van Zoelen; Yosef Yarden
The oncogenic ErbB-2/ErbB-3 heterodimer is a surrogate receptor of the epidermal growth factor and betacellulin.
Oncogene 1998;16(10):1249-58.
1998: Raya Eilam; Ronit Pinkas-Kramarski; BJ Ratzkin; Menahem Segal; Yosef Yarden
Activity-dependent regulation of Neu differentiation factor/neuregulin expression in rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1888-93.
1997: Ronit Pinkas-Kramarski; Raya Eilam; Iris Alroy; Gil Levkowitz; Peter Lonai; Yosef Yarden
Differential expression of NDF/neuregulin receptors ErbB-3 and ErbB-4 and involvement in inhibition of neuronal differentiation.
Oncogene 1997;15(23):2803-15.
1997: E Tzahar; Ronit Pinkas-Kramarski; JD Moyer; LN Klapper; Iris Alroy; Gil Levkowitz; Maya Shelly; S Henis; Miriam Eisenstein; BJ Ratzkin; Michael Sela; glenn andrews; Yosef Yarden
Bivalence of EGF-like ligands drives the ErbB signaling network.
The EMBO journal 1997;16(16):4938-50.
1997: LN Klapper; Nora Vaisman; E Hurwitz; Ronit Pinkas-Kramarski; Yosef Yarden; Michael Sela
A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors.
Oncogene 1997;14(17):2099-109.
1997: Ronit Pinkas-Kramarski; Iris Alroy; Yosef Yarden
ErbB receptors and EGF-like ligands: cell lineage determination and oncogenesis through combinatorial signaling.
Journal of mammary gland biology and neoplasia 1997;2(2):97-107.
1996: Ronit Pinkas-Kramarski; Maya Shelly; S Glathe; B J Ratzkin; Yosef Yarden
Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations.
The Journal of biological chemistry 1996;271(32):19029-32.
1996: Ronit Pinkas-Kramarski; L Soussan; Hadassa Waterman; Gil Levkowitz; Iris Alroy; LN Klapper; S Lavi; Rony Seger; B J Ratzkin; Michael Sela; Yosef Yarden
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions.
The EMBO journal 1996;15(10):2452-67.
1995: Moshe Marikovsky; S Lavi; Ronit Pinkas-Kramarski; Devarajan Karunagaran; N Liu; D Wen; Yosef Yarden
ErbB-3 mediates differential mitogenic effects of NDF/heregulin isoforms on mouse keratinocytes.
Oncogene 1995;10(7):1403-11.
1994: Ronit Pinkas-Kramarski; Raya Eilam; O Spiegler; S Lavi; N Liu; D Chang; D Wen; Michal Schwartz; Yosef Yarden
Brain neurons and glial cells express Neu differentiation factor/heregulin: a survival factor for astrocytes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9387-91.