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Lorenzo Pinna

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
82
Meggio, Flavio
72
Marin, Oriano
54
Sarno, Stefania
53
Donella-Deana, Arianna
42
Ruzzene, Maria
37
Brunati, Anna Maria
28
Cesaro, Luca
22
Pagano, Mario
17
Issinger, Olaf-Georg
16
Borin, Gianfranco
15
Calderan, Andrea
14
Battistutta, Roberto
14
Perich, John
13
Ruzza, Paolo
12
Boldyreff, Brigitte

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Publications

TOP 3
Gianoncelli Alessandra; Cozza Giorgio; Orzeszko Andrzej; Meggio Flavio; Kazimierczuk Zygmunt; Pinna Lorenzo A
Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2.
Di Maira Giovanni; Brustolon Francesca; Pinna Lorenzo A; Ruzzene Maria
Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells.
Salvi Mauro; Xu Dong; Chen Yingyu; Cabrelle Anna; Sarno Stefania; Pinna Lorenzo A
Programmed cell death protein 5 (PDCD5) is phosphorylated by CK2 in vitro and in 293T cells.

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All Publications

2009: Gianoncelli Alessandra; Cozza Giorgio; Orzeszko Andrzej; Meggio Flavio; Kazimierczuk Zygmunt; Pinna Lorenzo A
Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2.
Bioorganic & medicinal chemistry 2009;17(20):7281-9.
2009: Di Maira Giovanni; Brustolon Francesca; Pinna Lorenzo A; Ruzzene Maria
Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells.
Cellular and molecular life sciences : CMLS 2009;66(20):3363-73.
2009: Salvi Mauro; Xu Dong; Chen Yingyu; Cabrelle Anna; Sarno Stefania; Pinna Lorenzo A
Programmed cell death protein 5 (PDCD5) is phosphorylated by CK2 in vitro and in 293T cells.
Biochemical and biophysical research communications 2009;387(3):606-10.
2009: Cozza Giorgio; Mazzorana Marco; Papinutto Elena; Bain Jenny; Elliott Matthew; di Maira Giovanni; Gianoncelli Alessandra; Pagano Mario A; Sarno Stefania; Ruzzene Maria; Battistutta Roberto; Meggio Flavio; Moro Stefano; Zagotto Giuseppe; Pinna Lorenzo A
Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2.
The Biochemical journal 2009;421(3):387-95.
2009: Pinna L A; Allende J E
Protein kinase CK2 in health and disease: Protein kinase CK2: an ugly duckling in the kinome pond.
Cellular and molecular life sciences : CMLS 2009;66(11-12):1795-9.
2009: Salvi Mauro; Sarno Stefania; Cesaro Luca; Nakamura Hideji; Pinna Lorenzo A
Extraordinary pleiotropy of protein kinase CK2 revealed by weblogo phosphoproteome analysis.
Biochimica et biophysica acta 2009;1793(5):847-59.
2009: Frasson Martina; Vitadello Maurizio; Brunati Anna Maria; La Rocca Nicoletta; Tibaldi Elena; Pinna Lorenzo A; Gorza Luisa; Donella-Deana Arianna
Grp94 is Tyr-phosphorylated by Fyn in the lumen of the endoplasmic reticulum and translocates to Golgi in differentiating myoblasts.
Biochimica et biophysica acta 2009;1793(2):239-52.
2008: Peggion Caterina; Lopreiato Raffaele; Casanova Elena; Ruzzene Maria; Facchin Sonia; Pinna Lorenzo A; Carignani Giovanna; Sartori Geppo
Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt / PKB subfamily.
The FEBS journal 2008;275(23):5919-33.
2008: Iori Elisabetta; Millioni Renato; Puricelli Lucia; Arrigoni Giorgio; Lenzini Livia; Trevisan Roberto; James Peter; Rossi Gian Paolo; Pinna Lorenzo A; Tessari Paolo
Glycolytic enzyme expression and pyruvate kinase activity in cultured fibroblasts from type 1 diabetic patients with and without nephropathy.
Biochimica et biophysica acta 2008;1782(11):627-33.
2008: Vilk Greg; Weber Jane E; Turowec Jacob P; Duncan James S; Wu Chenggang; Derksen D Richard; Zien Piotr; Sarno Stefania; Donella-Deana Arianna; Lajoie Gilles; Pinna Lorenzo A; Li Shawn S C; Litchfield David W
Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells.
Cellular signalling 2008;20(11):1942-51.
2008: Pagano Mario A; Bain Jenny; Kazimierczuk Zygmunt; Sarno Stefania; Ruzzene Maria; Di Maira Giovanni; Elliott Matthew; Orzeszko Andrzej; Cozza Giorgio; Meggio Flavio; Pinna Lorenzo A
The selectivity of inhibitors of protein kinase CK2: an update.
The Biochemical journal 2008;415(3):353-65.
2008: Cozza Giorgio; Gianoncelli Alessandra; Montopoli Monica; Caparrotta Laura; Venerando Andrea; Meggio Flavio; Pinna Lorenzo A; Zagotto Giuseppe; Moro Stefano
Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.
Bioorganic & medicinal chemistry letters 2008;18(20):5672-5.
2008: Sarno Stefania; Pinna Lorenzo A
Protein kinase CK2 as a druggable target.
Molecular bioSystems 2008;4(9):889-94.
2008: Mazzorana Marco; Pinna Lorenzo A; Battistutta Roberto
A structural insight into CK2 inhibition.
Molecular and cellular biochemistry 2008;316(1-2):57-62.
2008: Di Maira Giovanni; Brustolon Francesca; Tosoni Kendra; Belli Sara; Krämer Stefanie D; Pinna Lorenzo A; Ruzzene Maria
Comparative analysis of CK2 expression and function in tumor cell lines displaying sensitivity vs. resistance to chemical induced apoptosis.
Molecular and cellular biochemistry 2008;316(1-2):155-61.
2008: Poletto Giorgia; Vilardell Jordi; Marin Oriano; Pagano Mario A; Cozza Giorgio; Sarno Stefania; Falqués Antoni; Itarte Emilio; Pinna Lorenzo A; Meggio Flavio
The regulatory beta subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2 beta-derived peptide.
Biochemistry 2008;47(32):8317-25.
2008: Pagano Mario A; Arrigoni Giorgio; Marin Oriano; Sarno Stefania; Meggio Flavio; Treharne Kate J; Mehta Anil; Pinna Lorenzo A
Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis.
Biochemistry 2008;47(30):7925-36.
2008: Arrigoni Giorgio; Pagano Mario A; Sarno Stefania; Cesaro Luca; James Peter; Pinna Lorenzo A
Mass spectrometry analysis of a protein kinase CK2beta subunit interactome isolated from mouse brain by affinity chromatography.
Journal of proteome research 2008;7(3):990-1000.
2008: Chilin Adriana; Battistutta Roberto; Bortolato Andrea; Cozza Giorgio; Zanatta Samuele; Poletto Giorgia; Mazzorana Marco; Zagotto Giuseppe; Uriarte Eugenio; Guiotto Adriano; Pinna Lorenzo A; Meggio Flavio; Moro Stefano
Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.
Journal of medicinal chemistry 2008;51(4):752-9.
2008: Tartari Carmen J; Gunby Rosalind H; Coluccia Addolorata M L; Sottocornola Roberta; Cimbro Barbara; Scapozza Leonardo; Donella-Deana Arianna; Pinna Lorenzo A; Gambacorti-Passerini Carlo
Characterization of some molecular mechanisms governing autoactivation of the catalytic domain of the anaplastic lymphoma kinase.
The Journal of biological chemistry 2008;283(7):3743-50.
2008: Wakata Aya; Cahill Sean M; Blumenstein Michael; Gunby Rosalind H; Jockusch Steffen; Marti Angel A; Cimbro Barbara; Gambacorti-Passerini Carlo; Donella-Deana Arianna; Pinna Lorenzo A; Turro Nicholas J; Lawrence David S
A mechanistic design principle for protein tyrosine kinase sensors: application to a validated cancer target.
Organic letters 2008;10(2):301-4.
2007: Dal Pero Francesca; Di Maira Giovanni; Marin Oriano; Bortoletto Gladis; Pinna Lorenzo A; Alberti Alfredo; Ruzzene Maria; Gerotto Martina
Heterogeneity of CK2 phosphorylation sites in the NS5A protein of different hepatitis C virus genotypes.
Journal of hepatology 2007;47(6):768-76.
2007: Ferrarese Anna; Marin Oriano; Bustos Victor H; Venerando Andrea; Antonelli Marcelo; Allende Jorge E; Pinna Lorenzo A
Chemical dissection of the APC Repeat 3 multistep phosphorylation by the concerted action of protein kinases CK1 and GSK3.
Biochemistry 2007;46(42):11902-10.
2007: Battistutta Roberto; Mazzorana Marco; Cendron Laura; Bortolato Andrea; Sarno Stefania; Kazimierczuk Zygmunt; Zanotti Giuseppe; Moro Stefano; Pinna Lorenzo A
The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules.
Chembiochem : a European journal of chemical biology 2007;8(15):1804-9.
2007: Facchin S; Ruzzene M; Peggion C; Sartori G; Carignani G; Marin O; Brustolon F; Lopreiato R; Pinna L A
Phosphorylation and activation of the atypical kinase p53-related protein kinase (PRPK) by Akt/PKB.
Cellular and molecular life sciences : CMLS 2007;64(19-20):2680-9.
2007: Di Maira G; Brustolon F; Bertacchini J; Tosoni K; Marmiroli S; Pinna L A; Ruzzene M
Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level.
Oncogene 2007;26(48):6915-26.
2007: Coluccia Addolorata Maria Luce; Vacca Angelo; Duñach Mireia; Mologni Luca; Redaelli Sara; Bustos Victor H; Benati Daniela; Pinna Lorenzo A; Gambacorti-Passerini Carlo
Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation.
The EMBO journal 2007;26(5):1456-66.
2007: Pagano Mario A; Poletto Giorgia; Di Maira Giovanni; Cozza Giorgio; Ruzzene Maria; Sarno Stefania; Bain Jenny; Elliott Matthew; Moro Stefano; Zagotto Giuseppe; Meggio Flavio; Pinna Lorenzo A
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors.
Chembiochem : a European journal of chemical biology 2007;8(1):129-39.
2006: Bustos Victor H; Ferrarese Anna; Venerando Andrea; Marin Oriano; Allende Jorge E; Pinna Lorenzo A
The first armadillo repeat is involved in the recognition and regulation of beta-catenin phosphorylation by protein kinase CK1.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(52):19725-30.
2006: Pagano M A; Cesaro L; Meggio F; Pinna L A
Protein kinase CK2: a newcomer in the 'druggable kinome'.
Biochemical Society transactions 2006;34(Pt 6):1303-6.
2006: Piazza Francesco A; Ruzzene Maria; Gurrieri Carmela; Montini Barbara; Bonanni Luca; Chioetto Gino; Di Maira Giovanni; Barbon Francesca; Cabrelle Anna; Zambello Renato; Adami Fausto; Trentin Livio; Pinna Lorenzo A; Semenzato Gianpietro
Multiple myeloma cell survival relies on high activity of protein kinase CK2.
Blood 2006;108(5):1698-707.
2006: Coccetti Paola; Zinzalla Vittoria; Tedeschi Gabriella; Russo Gian Luigi; Fantinato Sonia; Marin Oriano; Pinna Lorenzo A; Vanoni Marco; Alberghina Lilia
Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells.
Biochemical and biophysical research communications 2006;346(3):786-93.
2006: Salvi Mauro; Sarno Stefania; Marin Oriano; Meggio Flavio; Itarte Emilio; Pinna Lorenzo A
Discrimination between the activity of protein kinase CK2 holoenzyme and its catalytic subunits.
FEBS letters 2006;580(16):3948-52.
2006: Ruzza Paolo; Siligardi Giuliano; Donella-Deana Arianna; Calderan Andrea; Hussain Rohanah; Rubini Chiara; Cesaro Luca; Osler Alessio; Guiotto Andrea; Pinna Lorenzo A; Borin Gianfranco
4-Fluoroproline derivative peptides: effect on PPII conformation and SH3 affinity.
Journal of peptide science : an official publication of the European Peptide Society 2006;12(7):462-71.
2006: Cozza Giorgio; Bonvini Paolo; Zorzi Elisa; Poletto Giorgia; Pagano Mario A; Sarno Stefania; Donella-Deana Arianna; Zagotto Giuseppe; Rosolen Angelo; Pinna Lorenzo A; Meggio Flavio; Moro Stefano
Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application.
Journal of medicinal chemistry 2006;49(8):2363-6.
2006: Ruzza Paolo; Cesaro Luca; Tourwé Dirk; Calderan Andrea; Biondi Barbara; Maes Veronique; Menegazzo Ileana; Osler Alessio; Rubini Chiara; Guiotto Andrea; Pinna Lorenzo A; Borin Gianfranco; Donella-Deana Arianna
Spatial conformation and topography of the tyrosine aromatic ring in substrate recognition by protein tyrosine kinases.
Journal of medicinal chemistry 2006;49(6):1916-24.
2006: Tibaldi E; Arrigoni G; Brunati A M; James P; Pinna L A
Analysis of a sub-proteome which co-purifies with and is phosphorylated by the Golgi casein kinase.
Cellular and molecular life sciences : CMLS 2006;63(3):378-89.
2005: Sarno Stefania; Salvi Mauro; Battistutta Roberto; Zanotti Giuseppe; Pinna Lorenzo A
Features and potentials of ATP-site directed CK2 inhibitors.
Biochimica et biophysica acta 2005;1754(1-2):263-70.
2005: Battistutta Roberto; Mazzorana Marco; Sarno Stefania; Kazimierczuk Zygmunt; Zanotti Giuseppe; Pinna Lorenzo A
Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole.
Chemistry & biology 2005;12(11):1211-9.
2005: Barberis Matteo; Pagano Mario A; Gioia Luca De; Marin Oriano; Vanoni Marco; Pinna Lorenzo A; Alberghina Lilia
CK2 regulates in vitro the activity of the yeast cyclin-dependent kinase inhibitor Sic1.
Biochemical and biophysical research communications 2005;336(4):1040-8.
2005: Bustos Victor H; Marin Oriano; Meggio Flavio; Cesaro Luca; Allende Catherine C; Allende Jorge E; Pinna Lorenzo A
Generation of protein kinase Ck1alpha mutants which discriminate between canonical and non-canonical substrates.
The Biochemical journal 2005;391(Pt 2):417-24.
2005: Ferrari Stefano; Marin Oriano; Pagano Mario A; Meggio Flavio; Hess Daniel; El-Shemerly Mahmoud; Krystyniak Agnieszka; Pinna Lorenzo A
Aurora-A site specificity: a study with synthetic peptide substrates.
The Biochemical journal 2005;390(Pt 1):293-302.
2005: Sarno Stefania; Ruzzene Maria; Frascella Pietrogiulio; Pagano Mario A; Meggio Flavio; Zambon Alfonso; Mazzorana Marco; Di Maira Giovanni; Lucchini Vittorio; Pinna Lorenzo A
Development and exploitation of CK2 inhibitors.
Molecular and cellular biochemistry 2005;274(1-2):69-76.
2005: Llorens Franc; Sarno Stefania; Sarró Eduard; Duarri Anna; Roher Nerea; Meggio Flavio; Plana Maria; Pinna Lorenzo A; Itarte Emilio
Cross talk between protein kinase CK2 and eukaryotic translation initiation factor eIF2beta subunit.
Molecular and cellular biochemistry 2005;274(1-2):53-61.
2005: Pagano Mario A; Sarno Stefania; Poletto Giorgia; Cozza Giorgio; Pinna Lorenzo A; Meggio Flavio
Autophosphorylation at the regulatory beta subunit reflects the supramolecular organization of protein kinase CK2.
Molecular and cellular biochemistry 2005;274(1-2):23-9.
2005: Donella-Deana Arianna; Marin Oriano; Cesaro Luca; Gunby Rosalind H; Ferrarese Anna; Coluccia Addolorata M L; Tartari Carmen J; Mologni Luca; Scapozza Leonardo; Gambacorti-Passerini Carlo; Pinna Lorenzo A
Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity.
Biochemistry 2005;44(23):8533-42.
2005: Di Maira G; Salvi M; Arrigoni G; Marin O; Sarno S; Brustolon F; Pinna L A; Ruzzene M
Protein kinase CK2 phosphorylates and upregulates Akt/PKB.
Cell death and differentiation 2005;12(6):668-77.
2005: Brunati Anna Maria; Deana Renzo; Folda Alessandra; Massimino Maria Lina; Marin Oriano; Ledro Silvia; Pinna Lorenzo A; Donella-Deana Arianna
Thrombin-induced tyrosine phosphorylation of HS1 in human platelets is sequentially catalyzed by Syk and Lyn tyrosine kinases and associated with the cellular migration of the protein.
The Journal of biological chemistry 2005;280(22):21029-35.
2005: Contri Antonella; Brunati Anna Maria; Trentin Livio; Cabrelle Anna; Miorin Marta; Cesaro Luca; Pinna Lorenzo A; Zambello Renato; Semenzato Gianpietro; Donella-Deana Arianna
Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.
The Journal of clinical investigation 2005;115(2):369-78.
2004: Pagano Mario A; Andrzejewska Mariola; Ruzzene Maria; Sarno Stefania; Cesaro Luca; Bain Jenny; Elliott Matthew; Meggio Flavio; Kazimierczuk Zygmunt; Pinna Lorenzo A
Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole.
Journal of medicinal chemistry 2004;47(25):6239-47.
2004: Meggio Flavio; Pagano Mario A; Moro Stefano; Zagotto Giuseppe; Ruzzene Maria; Sarno Stefania; Cozza Giorgio; Bain Jenny; Elliott Matthew; Deana Arianna Donella; Brunati Anna Maria; Pinna Lorenzo A
Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study.
Biochemistry 2004;43(40):12931-6.
2004: Arrigoni Giorgio; Marin Oriano; Pagano Mario A; Settimo Luca; Paolin Bruno; Meggio Flavio; Pinna Lorenzo A
Phosphorylation of calmodulin fragments by protein kinase CK2. Mechanistic aspects and structural consequences.
Biochemistry 2004;43(40):12788-98.
2004: Pagano Mario A; Meggio Flavio; Ruzzene Maria; Andrzejewska Mariola; Kazimierczuk Zygmunt; Pinna Lorenzo A
2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2.
Biochemical and biophysical research communications 2004;321(4):1040-4.
2004: Lopreiato Raffaele; Facchin Sonia; Sartori Geppo; Arrigoni Giorgio; Casonato Stefano; Ruzzene Maria; Pinna Lorenzo A; Carignani Giovanna
Analysis of the interaction between piD261/Bud32, an evolutionarily conserved protein kinase of Saccharomyces cerevisiae, and the Grx4 glutaredoxin.
The Biochemical journal 2004;377(Pt 2):395-405.
2003: Llorens Franc; Roher Nerea; Miró Francesc A; Sarno Stefania; Ruiz F Xavier; Meggio Flavio; Plana Maria; Pinna Lorenzo A; Itarte Emilio
Eukaryotic translation-initiation factor eIF2beta binds to protein kinase CK2: effects on CK2alpha activity.
The Biochemical journal 2003;375(Pt 3):623-31.
2003: Procino Giuseppe; Carmosino Monica; Marin Oriano; Brunati Anna M; Contri Antonella; Pinna Lorenzo A; Mannucci Roberta; Nielsen Soren; Kwon Tae-Hwan; Svelto Maria; Valenti Giovanna
Ser-256 phosphorylation dynamics of Aquaporin 2 during maturation from the ER to the vesicular compartment in renal cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(13):1886-8.
2003: Marin Oriano; Bustos Victor H; Cesaro Luca; Meggio Flavio; Pagano Mario A; Antonelli Marcelo; Allende Catherine C; Pinna Lorenzo A; Allende Jorge E
A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10193-200.
2003: Sarno Stefania; de Moliner Erika; Ruzzene Maria; Pagano Mario A; Battistutta Roberto; Bain Jenny; Fabbro Doriano; Schoepfer Joseph; Elliott Matthew; Furet Pascal; Meggio Flavio; Zanotti Giuseppe; Pinna Lorenzo A
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).
The Biochemical journal 2003;374(Pt 3):639-46.
2003: Facchin Sonia; Lopreiato Raffaele; Ruzzene Maria; Marin Oriano; Sartori Geppo; Götz Claudia; Montenarh Mathias; Carignani Giovanna; Pinna Lorenzo A
Functional homology between yeast piD261/Bud32 and human PRPK: both phosphorylate p53 and PRPK partially complements piD261/Bud32 deficiency.
FEBS letters 2003;549(1-3):63-6.
2003: Pinna Lorenzo A
The raison d'être of constitutively active protein kinases: the lesson of CK2.
Accounts of chemical research 2003;36(6):378-84.
2003: Donella-Deana Arianna; Cesaro Luca; Sarno Stefania; Ruzzene Maria; Brunati Anna Maria; Marin Oriano; Vilk Greg; Doherty-Kirby Amanda; Lajoie Gilles; Litchfield David W; Pinna Lorenzo A
Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity.
The Biochemical journal 2003;372(Pt 3):841-9.
2003: Meggio Flavio; Pinna Lorenzo A
One-thousand-and-one substrates of protein kinase CK2?
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(3):349-68.
2003: De Moliner Erika; Moro Stefano; Sarno Stefania; Zagotto Giuseppe; Zanotti Giuseppe; Pinna Lorenzo A; Battistutta Roberto
Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight.
The Journal of biological chemistry 2003;278(3):1831-6.
2003: Donella-Deana Arianna; Boschetti Marco; Pinna Lorenzo A
Monitoring of PP2A and PP2C by phosphothreonyl peptide substrates.
Methods in enzymology 2003;366():3-17.
2003: Ruzza Paolo; Calderan Andrea; Donella-Deana Arianna; Biondi Barbara; Cesaro Luca; Osler Alessio; Elardo Stefano; Guiotto Andrea; Pinna Lorenzo A; Borin Gianfranco
Conformational constraints of tyrosine in protein tyrosine kinase substrates: Information about preferred bioactive side-chain orientation.
Biopolymers 2003;71(4):478-88.
2002: Pinna Lorenzo A
Protein kinase CK2: a challenge to canons.
Journal of cell science 2002;115(Pt 20):3873-8.
2002: Facchin Sonia; Sarno Stefania; Marin Oriano; Lopreiato Raffaele; Sartori Geppo; Pinna Lorenzo A
Acidophilic character of yeast PID261/BUD32, a putative ancestor of eukaryotic protein kinases.
Biochemical and biophysical research communications 2002;296(5):1366-71.
2002: Donella-Deana Arianna; Ruzza Paolo; Cesaro Luca; Brunati Anna Maria; Calderan Andrea; Borin Gianfranco; Pinna Lorenzo A
Specific monitoring of Syk protein kinase activity by peptide substrates including constrained analogs of tyrosine.
FEBS letters 2002;523(1-3):48-52.
2002: Facchin Sonia; Lopreiato Raffaele; Stocchetto Silvia; Arrigoni Giorgio; Cesaro Luca; Marin Oriano; Carignani Giovanna; Pinna Lorenzo A
Structure-function analysis of yeast piD261/Bud32, an atypical protein kinase essential for normal cell life.
The Biochemical journal 2002;364(Pt 2):457-63.
2002: Sarno Stefania; Ghisellini Paola; Pinna Lorenzo A
Unique activation mechanism of protein kinase CK2. The N-terminal segment is essential for constitutive activity of the catalytic subunit but not of the holoenzyme.
The Journal of biological chemistry 2002;277(25):22509-14.
2002: Ruzzene Maria; Penzo Daniele; Pinna Lorenzo A
Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells.
The Biochemical journal 2002;364(Pt 1):41-7.
2002: Sarno Stefania; Moro Stefano; Meggio Flavio; Zagotto Giuseppe; Dal Ben Diego; Ghisellini Paola; Battistutta Roberto; Zanotti Giuseppe; Pinna Lorenzo A
Toward the rational design of protein kinase casein kinase-2 inhibitors.
Pharmacology & therapeutics 2002;93(2-3):159-68.
2002: Negro Alessandro; Brunati Anna Maria; Donella-Deana Arianna; Massimino Maria Lina; Pinna Lorenzo A
Multiple phosphorylation of alpha-synuclein by protein tyrosine kinase Syk prevents eosin-induced aggregation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(2):210-2.
2002: Marin Oriano; Burzio Veronica; Boschetti Marco; Meggio Flavio; Allende Catherine C; Allende Jorge E; Pinna Lorenzo A
Structural features underlying the multisite phosphorylation of the A domain of the NF-AT4 transcription factor by protein kinase CK1.
Biochemistry 2002;41(2):618-27.
2001: Meggio F; Marin O; Boschetti M; Sarno S; Pinna L A
HIV-1 Rev transactivator: a beta-subunit directed substrate and effector of protein kinase CK2.
Molecular and cellular biochemistry 2001;227(1-2):145-51.
2001: Sarno S; Ghisellini P; Cesaro L; Battistutta R; Pinna L A
Generation of mutants of CK2alpha which are dependent on the beta-subunit for catalytic activity.
Molecular and cellular biochemistry 2001;227(1-2):13-9.
2001: Battistutta R; De Moliner E; Sarno S; Zanotti G; Pinna L A
Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole.
Protein science : a publication of the Protein Society 2001;10(11):2200-6.
2001: Roher N; Sarno S; Miró F; Ruzzene M; Llorens F; Meggio F; Itarte E; Pinna L A; Plana M
The carboxy-terminal domain of Grp94 binds to protein kinase CK2 alpha but not to CK2 holoenzyme.
FEBS letters 2001;505(1):42-6.
2001: Donella-Deana A; Cesaro L; Sarno S; Brunati A M; Ruzzene M; Pinna L A
Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182.
The Biochemical journal 2001;357(Pt 2):563-7.
2001: Brunati A M; Marin O; Folda A; Meggio F; Pinna L A
Possible implication of the Golgi apparatus casein kinase in the phosphorylation of vesicle docking protein p115 Ser-940: a study with peptide substrates.
Biochemical and biophysical research communications 2001;284(3):817-22.
2001: Sarno S; Reddy H; Meggio F; Ruzzene M; Davies S P; Donella-Deana A; Shugar D; Pinna L A
Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').
FEBS letters 2001;496(1):44-8.
2001: Ruzza P; Donella-Deana A; Calderan A; Brunati A; Massimino M L; Elardo S; Mattiazzo A; Pinna L A; Borin G
Antennapedia/HS1 chimeric phosphotyrosyl peptide: conformational properties, binding capability to c-Fgr SH2 domain and cell permeability.
Biopolymers 2001;60(4):290-306.
2000: D'Agostino D M; Ferro T; Zotti L; Meggio F; Pinna L A; Chieco-Bianchi L; Ciminale V
Identification of a domain in human immunodeficiency virus type 1 rev that is required for functional activity and modulates association with subnuclear compartments containing splicing factor SC35.
Journal of virology 2000;74(24):11899-910.
2000: Meggio F; Negro A; Sarno S; Ruzzene M; Bertoli A; Sorgato M C; Pinna L A
Bovine prion protein as a modulator of protein kinase CK2.
The Biochemical journal 2000;352 Pt 1():191-6.
2000: Brunati A M; Marin O; Bisinella A; Salviati A; Pinna L A
Novel consensus sequence for the Golgi apparatus casein kinase, revealed using proline-rich protein-1 (PRP1)-derived peptide substrates.
The Biochemical journal 2000;351 Pt 3():765-8.
2000: Sarno S; Marin O; Boschetti M; Pagano M A; Meggio F; Pinna L A
Cooperative modulation of protein kinase CK2 by separate domains of its regulatory beta-subunit.
Biochemistry 2000;39(40):12324-9.
2000: Marin O; Sarno S; Boschetti M; Pagano M A; Meggio F; Ciminale V; D'Agostino D M; Pinna L A
Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 ('casein kinase-2').
FEBS letters 2000;481(1):63-7.
2000: Battistutta R; Sarno S; De Moliner E; Papinutto E; Zanotti G; Pinna L A
The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2.
The Journal of biological chemistry 2000;275(38):29618-22.
2000: Brunati A M; Bordin L; Clari G; James P; Quadroni M; Baritono E; Pinna L A; Donella-Deana A
Sequential phosphorylation of protein band 3 by Syk and Lyn tyrosine kinases in intact human erythrocytes: identification of primary and secondary phosphorylation sites.
Blood 2000;96(4):1550-7.
2000: Battistutta R; Sarno S; De Moliner E; Marin O; Issinger O G; Zanotti G; Pinna L A
The crystal structure of the complex of Zea mays alpha subunit with a fragment of human beta subunit provides the clue to the architecture of protein kinase CK2 holoenzyme.
European journal of biochemistry / FEBS 2000;267(16):5184-90.
2000: Ruzzene M; Brunati A M; Sarno S; Marin O; Donella-Deana A; Pinna L A
Ser/Thr phosphorylation of hematopoietic specific protein 1 (HS1): implication of protein kinase CK2.
European journal of biochemistry / FEBS 2000;267(10):3065-72.
2000: Negro A; Meggio F; Bertoli A; Battistutta R; Sorgato M C; Pinna L A
Susceptibility of the prion protein to enzymic phosphorylation.
Biochemical and biophysical research communications 2000;271(2):337-41.
2000: Brunati A M; Contri A; Muenchbach M; James P; Marin O; Pinna L A
GRP94 (endoplasmin) co-purifies with and is phosphorylated by Golgi apparatus casein kinase.
FEBS letters 2000;471(2-3):151-5.
2000: Meggio F; Ruzzene M; Sarno S; Pagano M A; Pinna L A
pCMB treatment reveals the essential role of cysteinyl residues in conferring functional competence to the regulatory subunit of protein kinase CK2.
Biochemical and biophysical research communications 2000;267(1):427-32.
1999: Ruzzene M; Brunati A M; Sarno S; Donella-Deana A; Pinna L A
Hematopoietic lineage cell specific protein 1 associates with and down-regulates protein kinase CK2.
FEBS letters 1999;461(1-2):32-6.
1999: Marin O; Meggio F; Sarno S; Cesaro L; Pagano M A; Pinna L A
Tyrosine versus serine/threonine phosphorylation by protein kinase casein kinase-2. A study with peptide substrates derived from immunophilin Fpr3.
The Journal of biological chemistry 1999;274(41):29260-5.
1999: Guerra B; Boldyreff B; Sarno S; Cesaro L; Issinger O G; Pinna L A
CK2: a protein kinase in need of control.
Pharmacology & therapeutics 1999;82(2-3):303-13.
1999: Pulgar V; Marin O; Meggio F; Allende C C; Allende J E; Pinna L A
Optimal sequences for non-phosphate-directed phosphorylation by protein kinase CK1 (casein kinase-1)--a re-evaluation.
European journal of biochemistry / FEBS 1999;260(2):520-6.
1999: Marin O; Meggio F; Pinna L A
Structural features underlying the unusual mode of calmodulin phosphorylation by protein kinase CK2: A study with synthetic calmodulin fragments.
Biochemical and biophysical research communications 1999;256(2):442-6.
1999: Brunati A M; Donella-Deana A; James P; Quadroni M; Contri A; Marin O; Pinna L A
Molecular features underlying the sequential phosphorylation of HS1 protein and its association with c-Fgr protein-tyrosine kinase.
The Journal of biological chemistry 1999;274(11):7557-64.
1999: Meggio F; Marin O; Sarno S; Pinna L A
Functional analysis of CK2beta-derived synthetic fragments.
Molecular and cellular biochemistry 1999;191(1-2):35-42.
1999: Sarno S; Vaglio P; Cesaro L; Marin O; Pinna L A
A multifunctional network of basic residues confers unique properties to protein kinase CK2.
Molecular and cellular biochemistry 1999;191(1-2):13-9.
1998: Sarno S; Marin O; Ghisellini P; Meggio F; Pinna L A
Biochemical evidence that the N-terminal segments of the alpha subunit and the beta subunit play interchangeable roles in the activation of protein kinase CK2.
FEBS letters 1998;441(1):29-33.
1998: Ruzza P; Donella-Deana A; Calderan A; Zanotti G; Cesaro L; Pinna L A; Borin G
Linear and cyclic peptides as substrates for Lyn tyrosine kinase.
Journal of peptide science : an official publication of the European Peptide Society 1998;4(1):33-45.
1998: Brunati A M; Pinna L A; Bergantino E; Ruzzene M; Cirri P; Ramponi G; Donella-Deana A
Src homology-2 domains protect phosphotyrosyl residues against enzymatic dephosphorylation.
Biochemical and biophysical research communications 1998;243(3):700-5.
1998: Donella-Deana A; Cesaro L; Ruzzene M; Brunati A M; Marin O; Pinna L A
Spontaneous autophosphorylation of Lyn tyrosine kinase at both its activation segment and C-terminal tail confers altered substrate specificity.
Biochemistry 1998;37(5):1438-46.
1997: Lasa M; Chang P L; Prince C W; Pinna L A
Phosphorylation of osteopontin by Golgi apparatus casein kinase.
Biochemical and biophysical research communications 1997;240(3):602-5.
1997: Sarno S; Vaglio P; Marin O; Meggio F; Issinger O G; Pinna L A
Basic residues in the 74-83 and 191-198 segments of protein kinase CK2 catalytic subunit are implicated in negative but not in positive regulation by the beta-subunit.
European journal of biochemistry / FEBS 1997;248(2):290-5.
1997: Sarno S; Vaglio P; Marin O; Issinger O G; Ruffato K; Pinna L A
Mutational analysis of residues implicated in the interaction between protein kinase CK2 and peptide substrates.
Biochemistry 1997;36(39):11717-24.
1997: Stocchetto S; Marin O; Carignani G; Pinna L A
Biochemical evidence that Saccharomyces cerevisiae YGR262c gene, required for normal growth, encodes a novel Ser/Thr-specific protein kinase.
FEBS letters 1997;414(1):171-5.
1997: Ruzzene M; Songyang Z; Marin O; Donella-Deana A; Brunati A M; Guerra B; Agostinis P; Cantley L C; Pinna L A
Sequence specificity of C-terminal Src kinase (CSK)--a comparison with Src-related kinases c-Fgr and Lyn.
European journal of biochemistry / FEBS 1997;246(2):433-9.
1997: Marin O; Meggio F; Sarno S; Pinna L A
Physical dissection of the structural elements responsible for regulatory properties and intersubunit interactions of protein kinase CK2 beta-subunit.
Biochemistry 1997;36(23):7192-8.
1997: Ruzzene M; Brunati A M; Donella-Deana A; Marin O; Pinna L A
Specific stimulation of c-Fgr kinase by tyrosine-phosphorylated (poly)peptides--possible implication in the sequential mode of protein phosphorylation.
European journal of biochemistry / FEBS 1997;245(3):701-7.
1997: Pinna L A
Protein kinase CK2.
The international journal of biochemistry & cell biology 1997;29(4):551-4.
1997: Lasa M; Marin O; Pinna L A
Rat liver Golgi apparatus contains a protein kinase similar to the casein kinase of lactating mammary gland.
European journal of biochemistry / FEBS 1997;243(3):719-25.
1997: Pinna L A; Meggio F
Protein kinase CK2 ("casein kinase-2") and its implication in cell division and proliferation.
Progress in cell cycle research 1997;3():77-97.
1996: Pinna L A; Ruzzene M
How do protein kinases recognize their substrates?
Biochimica et biophysica acta 1996;1314(3):191-225.
1996: Ruzza P; Donella-Deana A; Calderan A; Filippi B; Cesaro L; Pinna L A; Borin G
An exploration of the effects of constraints on the phosphorylation of synthetic protein tyrosine kinase peptide substrates.
Journal of peptide science : an official publication of the European Peptide Society 1996;2(5):325-38.
1996: Marin O; Meggio F; Perich J W; Pinna L A
Phosphotyrosine specifies the phosphorylation by protein kinase CK2 of a peptide reproducing the activation loop of the insulin receptor protein tyrosine kinase.
The international journal of biochemistry & cell biology 1996;28(9):999-1005.
1996: Brunati A M; James P; Guerra B; Ruzzene M; Donella-Deana A; Pinna L A
The spleen protein-tyrosine kinase TPK-IIB is highly similar to the catalytic domain of p72syk.
European journal of biochemistry / FEBS 1996;240(2):400-7.
1996: Meggio F; D'Agostino D M; Ciminale V; Chieco-Bianchi L; Pinna L A
Phosphorylation of HIV-1 Rev protein: implication of protein kinase CK2 and pro-directed kinases.
Biochemical and biophysical research communications 1996;226(2):547-54.
1996: Sarno S; Vaglio P; Meggio F; Issinger O G; Pinna L A
Protein kinase CK2 mutants defective in substrate recognition. Purification and kinetic analysis.
The Journal of biological chemistry 1996;271(18):10595-601.
1996: Ruzzene M; Brunati A M; Marin O; Donella-Deana A; Pinna L A
SH2 domains mediate the sequential phosphorylation of HS1 protein by p72syk and Src-related protein tyrosine kinases.
Biochemistry 1996;35(16):5327-32.
1996: Lasa-Benito M; Marin O; Meggio F; Pinna L A
Golgi apparatus mammary gland casein kinase: monitoring by a specific peptide substrate and definition of specificity determinants.
FEBS letters 1996;382(1-2):149-52.
1996: Agostinis P; Donella-Deana A; Van Hoof C; Cesaro L; Brunati A M; Ruzzene M; Merlevede W; Pinna L A; Goris J
A comparative study of the phosphotyrosyl phosphatase specificity of protein phosphatase type 2A and phosphotyrosyl phosphatase type 1B using phosphopeptides and the phosphoproteins p50/HS1, c-Fgr and Lyn.
European journal of biochemistry / FEBS 1996;236(2):548-57.
1996: Perich J W; Meggio F; Pinna L A
Solid phase synthesis of pp60src-related phosphopeptides via 'global' phosphorylation and their use as substrates for enzymatic phosphorylation by casein kinase-2.
Bioorganic & medicinal chemistry 1996;4(2):143-50.
1996: Vaglio P; Sarno S; Marin O; Meggio F; Issinger O G; Pinna L A
Mapping the residues of protein kinase CK2 alpha subunit responsible for responsiveness to polyanionic inhibitors.
FEBS letters 1996;380(1-2):25-8.
1996: Donella-Deana A; James P; Staudenmann W; Cesaro L; Marin O; Brunati A M; Ruzzene M; Pinna L A
Isolation from spleen of a 57-kDa protein substrate of the tyrosine kinase Lyn. Identification as a protein related to protein disulfide-isomerase and localisation of the phosphorylation sites.
European journal of biochemistry / FEBS 1996;235(1-2):18-25.
1995: Ruzza P; Deana A D; Calderan A; Pavanetto M; Cesaro L; Pinna L A; Borin G
Synthetic Tyr-phospho and non-hydrolyzable phosphonopeptides as PTKs and TC-PTP inhibitors.
International journal of peptide and protein research 1995;46(6):535-46.
1995: Brunati A M; Donella-Deana A; Ruzzene M; Marin O; Pinna L A
Site specificity of p72syk protein tyrosine kinase: efficient phosphorylation of motifs recognized by Src homology 2 domains of the Src family.
FEBS letters 1995;367(2):149-52.
1995: Meggio F; Boldyreff B; Marin O; Issinger O G; Pinna L A
Phosphorylation and activation of protein kinase CK2 by p34cdc2 are independent events.
European journal of biochemistry / FEBS 1995;230(3):1025-31.
1995: Ruzza P; Calderan A; Filippi B; Biondi B; Deana A D; Cesaro L; Pinna L A; Borin G
Linear and cyclic synthetic peptides related to the main autophosphorylation site of the Src tyrosine kinases as substrates and inhibitors of Lyn.
International journal of peptide and protein research 1995;45(6):529-39.
1995: Agostinis P; Vandenbogaerde A; Donella-Deana A; Pinna L A; Lee K T; Goris J; Merlevede W; Vandenheede J R; De Witte P
Photosensitized inhibition of growth factor-regulated protein kinases by hypericin.
Biochemical pharmacology 1995;49(11):1615-22.
1995: Brunati A M; Ruzzene M; James P; Guerra B; Pinna L A
Hierarchical phosphorylation of a 50-kDa protein by protein tyrosine kinases TPK-IIB and C-Fgr, and its identification as HS1 hematopoietic-lineage cell-specific protein.
European journal of biochemistry / FEBS 1995;229(1):164-70.
1995: Marin O; Meggio F; Boldyreff B; Issinger O G; Pinna L A
Dissection of the dual function of the beta-subunit of protein kinase CK2 ('casein kinase-2'): a synthetic peptide reproducing the carboxyl-terminal domain mimicks the positive but not the negative effects of the whole protein.
FEBS letters 1995;363(1-2):111-4.
1995: Sarno S; Boldyreff B; Marin O; Guerra B; Meggio F; Issinger O G; Pinna L A
Mapping the residues of protein kinase CK2 implicated in substrate recognition: mutagenesis of conserved basic residues in the alpha-subunit.
Biochemical and biophysical research communications 1995;206(1):171-9.
1994: Dobrowolska G; Meggio F; Marin O; Lozeman F J; Li D; Pinna L A; Krebs E G
Substrate recognition by casein kinase-II: the role of histidine-160.
FEBS letters 1994;355(3):237-41.
1994: Marin O; Meggio F; Sarno S; Andretta M; Pinna L A
Phosphorylation of synthetic fragments of inhibitor-2 of protein phosphatase-1 by casein kinase-1 and -2. Evidence that phosphorylated residues are not strictly required for efficient targeting by casein kinase-1.
European journal of biochemistry / FEBS 1994;223(2):647-53.
1994: Pinna L A; Donella-Deana A
Phosphorylated synthetic peptides as tools for studying protein phosphatases.
Biochimica et biophysica acta 1994;1222(3):415-31.
1994: Ruzzene M; James P; Brunati A M; Donella-Deana A; Pinna L A
Regulation of c-Fgr protein kinase by c-Src kinase (CSK) and by polycationic effectors.
The Journal of biological chemistry 1994;269(22):15885-91.
1994: Meggio F; Boldyreff B; Issinger O G; Pinna L A
Casein kinase 2 down-regulation and activation by polybasic peptides are mediated by acidic residues in the 55-64 region of the beta-subunit. A study with calmodulin as phosphorylatable substrate.
Biochemistry 1994;33(14):4336-42.
1994: Marin O; Meggio F; Pinna L A
Design and synthesis of two new peptide substrates for the specific and sensitive monitoring of casein kinases-1 and -2.
Biochemical and biophysical research communications 1994;198(3):898-905.
1994: Perich J W; Ruzzene M; Pinna L A; Reynolds E C
Efficient Fmoc/solid-phase peptide synthesis of O-phosphotyrosyl-containing peptides and their use as phosphatase substrates.
International journal of peptide and protein research 1994;43(1):39-46.
1994: Donella-Deana A; Krinks M H; Ruzzene M; Klee C; Pinna L A
Dephosphorylation of phosphopeptides by calcineurin (protein phosphatase 2B).
European journal of biochemistry / FEBS 1994;219(1-2):109-17.
1994: Meggio F; Marin O; Pinna L A
Substrate specificity of protein kinase CK2.
Cellular & molecular biology research 1994;40(5-6):401-9.
1994: Boldyreff B; Meggio F; Pinna L A; Issinger O G
Protein kinase CK2 structure-function relationship: effects of the beta subunit on reconstitution and activity.
Cellular & molecular biology research 1994;40(5-6):391-9.
1994: Pinna L A
A historical view of protein kinase CK2.
Cellular & molecular biology research 1994;40(5-6):383-90.
1993: Boldyreff B; Meggio F; Pinna L A; Issinger O G
Reconstitution of normal and hyperactivated forms of casein kinase-2 by variably mutated beta-subunits.
Biochemistry 1993;32(47):12672-7.
1993: Perich J W; Meggio F; Valerio R M; Johns R B; Pinna L A; Reynolds E C
The synthesis and use of pp60src-related peptides and phosphopeptides as substrates for enzymatic phosphorylation studies.
Bioorganic & medicinal chemistry 1993;1(5):381-8.
1993: Donella-Deana A; Marin O; Brunati A M; Cesaro L; Piutti C; Pinna L A
Phosphorylated residues as specificity determinants for an acidophilic protein tyrosine kinase. A study with src and cdc2 derived phosphopeptides.
FEBS letters 1993;330(2):141-5.
1993: Brunati A M; James P; Donella-Deana A; Matoskova B; Robbins K C; Pinna L A
Isolation and identification of two proto-oncogene products related to c-fgr and fyn in a tyrosine-protein-kinase fraction of rat spleen.
European journal of biochemistry / FEBS 1993;216(1):323-7.
1993: Donella-Deana A; Lavoinne A; Marin O; Pinna L A; Cohen P
An analysis of the substrate specificity of insulin-stimulated protein kinase-1, a mammalian homologue of S6 kinase-II.
Biochimica et biophysica acta 1993;1178(2):189-93.
1993: Sarno S; Marin O; Meggio F; Pinna L A
Polyamines as negative regulators of casein kinase-2: the phosphorylation of calmodulin triggered by polylysine and by the alpha[66-86] peptide is prevented by spermine.
Biochemical and biophysical research communications 1993;194(1):83-90.
1993: Meggio F; Boldyreff B; Issinger O G; Pinna L A
The autophosphorylation and p34cdc2 phosphorylation sites of casein kinase-2 beta-subunit are not essential for reconstituting the fully-active heterotetrameric holoenzyme.
Biochimica et biophysica acta 1993;1164(2):223-5.
1993: Donella-Deana A; Ostojic S; Pinna L A; Barbaric S
Specific dephosphorylation of phosphopeptides by the yeast alkaline phosphatase encoded by PHO8 gene.
Biochimica et biophysica acta 1993;1177(2):221-8.
1993: Boldyreff B; Meggio F; Dobrowolska G; Pinna L A; Issinger O G
Expression and characterization of a recombinant maize CK-2 alpha subunit.
Biochimica et biophysica acta 1993;1173(1):32-8.
1993: Ruzza P; Calderan A; Filippi B; Donella-Deana A; Pinna L A; Borin G
Synthesis and conformational studies on peptides corresponding to a putative autophosphorylation site of abl TPK.
International journal of peptide and protein research 1993;41(3):291-9.
1993: Ruzzene M; Donella-Deana A; Marin O; Perich J W; Ruzza P; Borin G; Calderan A; Pinna L A
Specificity of T-cell protein tyrosine phosphatase toward phosphorylated synthetic peptides.
European journal of biochemistry / FEBS 1993;211(1-2):289-95.
1992: Brunati A M; Allee G; Marin O; Donella-Deana A; Cesaro L; Bougeret C; Fagard R; Benarous R; Fischer S; Pinna L A
Spleen protein tyrosine kinases TPK-IIB and CSK display different immunoreactivity and opposite specificities toward c-src-derived peptides.
FEBS letters 1992;313(3):291-4.
1992: Boldyreff B; Meggio F; Pinna L A; Issinger O G
Casein kinase-2 structure-function relationship: creation of a set of mutants of the beta subunit that variably surrogate the wildtype beta subunit function.
Biochemical and biophysical research communications 1992;188(1):228-34.
1992: Perich J W; Meggio F; Reynolds E C; Marin O; Pinna L A
Role of phosphorylated aminoacyl residues in generating atypical consensus sequences which are recognized by casein kinase-2 but not by casein kinase-1.
Biochemistry 1992;31(25):5893-7.
1992: Agostinis P; Marin O; James P; Hendrix P; Merlevede W; Vandenheede J R; Pinna L A
Phosphorylation of the phosphatase modulator subunit (inhibitor-2) by casein kinase-1. Identification of the phosphorylation sites.
FEBS letters 1992;305(2):121-4.
1992: Meggio F; Boldyreff B; Marin O; Marchiori F; Perich J W; Issinger O G; Pinna L A
The effect of polylysine on casein-kinase-2 activity is influenced by both the structure of the protein/peptide substrates and the subunit composition of the enzyme.
European journal of biochemistry / FEBS 1992;205(3):939-45.
1992: Marin O; Meggio F; Draetta G; Pinna L A
The consensus sequences for cdc2 kinase and for casein kinase-2 are mutually incompatible. A study with peptides derived from the beta-subunit of casein kinase-2.
FEBS letters 1992;301(1):111-4.
1992: Donella-Deana A; Marin O; Brunati A M; Pinna L A
Selective effect of poly(lysine) on the enhancement of the lyn tyrosine protein kinase activity. Increased specificity toward src peptides.
European journal of biochemistry / FEBS 1992;204(3):1159-63.
1992: Jagiello I; Donella-Deana A; Szczegielniak J; Pinna L A; Muszynska G
Identification of protein phosphatase activities in maize seedlings.
Biochimica et biophysica acta 1992;1134(2):129-36.
1992: Dobrowolska G; Meggio F; Szczegielniak J; Muszynska G; Pinna L A
Purification and characterization of maize seedling casein kinase IIB, a monomeric enzyme immunologically related to the alpha subunit of animal casein kinase-2.
European journal of biochemistry / FEBS 1992;204(1):299-303.
1992: Meggio F; Boldyreff B; Marin O; Pinna L A; Issinger O G
Role of the beta subunit of casein kinase-2 on the stability and specificity of the recombinant reconstituted holoenzyme.
European journal of biochemistry / FEBS 1992;204(1):293-7.
1992: Meggio F; Perich J W; Marin O; Pinna L A
The comparative efficiencies of the Ser(P)-, Thr(P)- and Tyr(P)-residues as specificity determinants for casein kinase-1.
Biochemical and biophysical research communications 1992;182(3):1460-5.
1991: Donella-Deana A; Stone S R; Pinna L A
Specificity determinants for tyrosine protein kinase. A study with recombinant hirudin mutants.
European journal of biochemistry / FEBS 1991;201(2):501-5.
1991: Donella-Deana A; Varro A; Dockray G J; Pinna L A
Substitution of phosphotyrosine for sulphotyrosine in biologically active peptides. Enzymatic phosphorylation of a progastrin peptide confers immunoreactivity reminiscent of the sulphated derivative.
Biochimica et biophysica acta 1991;1095(1):75-7.
1991: Marin O; Donella-Deana A; Brunati A M; Fischer S; Pinna L A
Peptides reproducing the phosphoacceptor sites of pp60c-src as substrates for TPK-IIB, a splenic tyrosine kinase devoid of autophosphorylation activity.
The Journal of biological chemistry 1991;266(27):17798-803.
1991: Donella-Deana A; Meyer H E; Pinna L A
The use of phosphopeptides to distinguish between protein phosphatase and acid/alkaline phosphatase activities: opposite specificity toward phosphoseryl/phosphothreonyl substrates.
Biochimica et biophysica acta 1991;1094(1):130-3.
1991: Meggio F; Perich J W; Reynolds E C; Pinna L A
A synthetic beta-casein phosphopeptide and analogues as model substrates for casein kinase-1, a ubiquitous, phosphate directed protein kinase.
FEBS letters 1991;283(2):303-6.
1991: Meggio F; Perich J W; Reynolds E C; Pinna L A
Phosphotyrosine as a specificity determinant for casein kinase-2, a growth related Ser/Thr-specific protein kinase.
FEBS letters 1991;279(2):307-9.
1991: Brunati A M; Donella-Deana A; Ralph S; Marchiori F; Borin G; Fischer S; Pinna L A
Stimulation by NaCl, polylysine and heparin of two forms of spleen tyrosine protein kinase immunologically related with the protein expressed by lyn oncogene.
Biochimica et biophysica acta 1991;1091(1):123-6.
1990: Donella-Deana A; Brunati A M; Marchiori F; Borin G; Marin O; Pinna L A
Different specificities of spleen tyrosine protein kinases for synthetic peptide substrates.
European journal of biochemistry / FEBS 1990;194(3):773-7.
1990: Pinna L A
Casein kinase 2: an 'eminence grise' in cellular regulation?
Biochimica et biophysica acta 1990;1054(3):267-84.
1990: Perich J W; Meggio F; Kitas E A; Valerio R M; Johns R B; Pinna L A
Phosphorylation of src-phosphopeptides by casein kinases-1 and -2: favourable effect of phosphotyrosine.
Biochemical and biophysical research communications 1990;170(2):635-42.
1990: Agostinis P; Goris J; Pinna L A; Marchiori F; Perich J W; Meyer H E; Merlevede W
Synthetic peptides as model substrates for the study of the specificity of the polycation-stimulated protein phosphatases.
European journal of biochemistry / FEBS 1990;189(2):235-41.
1990: Donella Deana A; Mac Gowan C H; Cohen P; Marchiori F; Meyer H E; Pinna L A
An investigation of the substrate specificity of protein phosphatase 2C using synthetic peptide substrates; comparison with protein phosphatase 2A.
Biochimica et biophysica acta 1990;1051(2):199-202.
1990: Meggio F; Shugar D; Pinna L A
Ribofuranosyl-benzimidazole derivatives as inhibitors of casein kinase-2 and casein kinase-1.
European journal of biochemistry / FEBS 1990;187(1):89-94.
1989: Meggio F; Perich J W; Meyer H E; Hoffmann-Posorske E; Lennon D P; Johns R B; Pinna L A
Synthetic fragments of beta-casein as model substrates for liver and mammary gland casein kinases.
European journal of biochemistry / FEBS 1989;186(3):459-64.
1989: Cola C; Brunati A M; Borin G; Ruzza P; Calderan A; De Castiglione R; Pinna L A
Synthetic peptides reproducing the EGF-receptor segment homologous to the pp60v-src phosphoacceptor site. Phosphorylation by tyrosine protein kinases.
Biochimica et biophysica acta 1989;1012(2):191-5.
1989: Donella-Deana A; Monti E; Pinna L A
Inhibition of tyrosine protein kinases by the antineoplastic agent adriamycin.
Biochemical and biophysical research communications 1989;160(3):1309-15.
1989: Dobrowolska G; Meggio F; Marchiori F; Pinna L A
Specificity determinants of maize casein kinase-IIB are related to but distinct from those of rat liver casein kinase-2.
Biochimica et biophysica acta 1989;1010(2):274-7.
1989: Meggio F; Pinna L A
Random tyrosine and glutamic acid-containing polymers are very powerful inhibitors of casein kinase-2.
Biochimica et biophysica acta 1989;1010(1):128-30.
1988: Meggio F; Boulton A P; Marchiori F; Borin G; Lennon D P; Calderan A; Pinna L A
Substrate-specificity determinants for a membrane-bound casein kinase of lactating mammary gland. A study with synthetic peptides.
European journal of biochemistry / FEBS 1988;177(2):281-4.
1988: Marchiori F; Meggio F; Marin O; Borin G; Calderan A; Ruzza P; Pinna L A
Synthetic peptide substrates for casein kinase 2. Assessment of minimum structural requirements for phosphorylation.
Biochimica et biophysica acta 1988;971(3):332-8.
1988: Meggio F; Perich J W; Johns R B; Pinna L A
Partially dephosphorylated phosphopeptide AcSer(P)-Ser(P)-Ser(P) is an excellent substrate for casein kinase-2.
FEBS letters 1988;237(1-2):225-8.
1988: Meggio F; Pinna L A
Phosphorylation of phosvitin by casein kinase-2 provides the evidence that phosphoserines can replace carboxylic amino acids as specificity determinants.
Biochimica et biophysica acta 1988;971(2):227-31.
1988: Deana A D; Pinna L A
Identification of pseudo 'phosphothreonyl-specific' protein phosphatase T with a fraction of polycation-stimulated protein phosphatase 2A.
Biochimica et biophysica acta 1988;968(2):179-85.
1988: Ferrari S; Calderan A; Pinna L A
Mechanism of Ca2+ and phospholipid-independent protein phosphorylation by protein kinase C: protamines and related peptides as substrates and inhibitors.
Advances in experimental medicine and biology 1988;231():427-32.
1988: Pinna L A
Structural basis for the specificity of protein phosphorylation and dephosphorylation processes.
Advances in experimental medicine and biology 1988;231():433-43.
1987: Agostinis P; Goris J; Pinna L A; Merlevede W
Regulation of casein kinase 2 by phosphorylation/dephosphorylation.
The Biochemical journal 1987;248(3):785-9.
1987: Agostinis P; Vandenheede J R; Goris J; Meggio F; Pinna L A; Merlevede W
The ATP,Mg-dependent protein phosphatase: regulation by casein kinase-1.
FEBS letters 1987;224(2):385-90.
1987: Lopandic K; Deana A D; Barbaric S; Pinna L A
Biochemical and genetic evidence that yeast extracellular protein phosphatase activity is due to acid phosphatase.
Biochemistry international 1987;14(4):627-33.
1986: Donella-Deana A; Lopandic K; Barbaric S; Pinna L A
Distinct specificities of repressible acid phosphatase from yeast toward phosphoseryl and phosphotyrosyl phosphopeptides.
Biochemical and biophysical research communications 1986;139(3):1202-9.

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