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Daniel Pipeleers
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30
Gorus, Frans
19
Keymeulen, Bart
19
Schuit, Frans
18
Van Schravendijk, Chris
16
Eizirik, Decio
14
Weets, Ilse
12
Ling, Zhidong
9
Hellerström, Claes
8
Decochez, Katelijn
8
Vandewalle, CL
7
Truyen, I
7
Kaufman, Leonard
7
Mathieu, Chantal
6
De Leeuw, Ivo
6
Roep, Bart
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All Publications
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2009: Hilbrands Robert; Huurman Volkert A L; Gillard Pieter; Velthuis Jurjen H L; De Waele Marc; Mathieu Chantal; Kaufman Leonard; Pipeleers-Marichal Miriam; Ling Zhidong; Movahedi Babak; Jacobs-Tulleneers-Thevissen Daniel; Monbaliu Diethard; Ysebaert Dirk; Gorus Frans K; Roep Bart O; Pipeleers Daniel G; Keymeulen Bart
Differences in baseline lymphocyte counts and autoreactivity are associated with differences in outcome of islet cell transplantation in type 1 diabetic patients.
Diabetes 2009;58(10):2267-76.
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2009: Vandemeulebroucke E; Gorus F K; Decochez K; Weets I; Keymeulen B; De Block C; Tits J; Pipeleers D G; Mathieu C;
Insulin treatment in IA-2A-positive relatives of type 1 diabetic patients.
Diabetes & metabolism 2009;35(4):319-27.
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2009: Roelen D L; Huurman V A L; Hilbrands R; Gillard P; Duinkerken G; van der Meer-Prins P W M; Versteeg-van der Voort Maarschalk M F J; Mathieu C; Keymeulen B; Pipeleers D G; Roep B O; Claas F H J
Relevance of cytotoxic alloreactivity under different immunosuppressive regimens in clinical islet cell transplantation.
Clinical and experimental immunology 2009;156(1):141-8.
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2009: Huurman V A L; Velthuis J H L; Hilbrands R; Tree T I M; Gillard P; van der Meer-Prins P M W; Duinkerken G; Pinkse G G M; Keymeulen B; Roelen D L; Claas F H J; Pipeleers D G; Roep B O
Allograft-specific cytokine profiles associate with clinical outcome after islet cell transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(2):382-8.
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2008: De Pauw Pieter E M; Vermeulen Ilse; Ubani Ogonnaya C; Truyen Inge; Vekens Evilien M F; van Genderen Farah T; De Grijse Joeri W; Pipeleers Daniel G; Van Schravendijk Chris; Gorus Frans K
Simultaneous measurement of plasma concentrations of proinsulin and C-peptide and their ratio with a trefoil-type time-resolved fluorescence immunoassay.
Clinical chemistry 2008;54(12):1990-8.
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2008: Huurman Volkert A L; Hilbrands Robert; Pinkse Gabriëlle G M; Gillard Pieter; Duinkerken Gaby; van de Linde Pieter; van der Meer-Prins Petronella M W; Versteeg-van der Voort Maarschalk Minke F J; Verbeeck Koen; Alizadeh Behrooz Z; Mathieu Chantal; Gorus Frans K; Roelen Dave L; Claas Frans H J; Keymeulen Bart; Pipeleers Daniel G; Roep Bart O
Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation.
PloS one 2008;3(6):e2435.
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2007: Weets I; Rooman R; Coeckelberghs M; De Block C; Van Gaal L; Kaufman J-M; Keymeulen B; Mathieu C; Weber E; Pipeleers D G; Gorus F K;
The age at diagnosis of type 1 diabetes continues to decrease in Belgian boys but not in girls: a 15-year survey.
Diabetes/metabolism research and reviews 2007;23(8):637-43.
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2007: Truyen I; De Grijse J; Van Schravendijk C; De Smet D; Decochez K; Vandemeulebroucke E; Giri M; Keymeulen B; Mathieu C; Van Gaal L; De Pauw P; Weets I; Pipeleers D G; Gorus F K;
Adiponectin levels do not predict clinical onset of type 1 diabetes in antibody-positive relatives.
Diabetologia 2007;50(10):2143-6.
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2007: Truyen I; De Grijse J; Weets I; Kaufman L; Pipeleers L; Nanos N; Decochez K; Hilbrands R; Kaufman J-M; Keymeulen B; Mathieu C; Van Gaal L; Pipeleers D G; Gorus F K;
Identification of prediabetes in first-degree relatives at intermediate risk of type I diabetes.
Clinical and experimental immunology 2007;149(2):243-50.
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2007: Rui Mao; Hampe Christiane S; Wang Chen; Ling Zhidong; Gorus Frans K; Lernmark Ake; Pipeleers Daniel G; De Pauw Pieter E M
Species and epitope specificity of two 65 kDa glutamate decarboxylase time-resolved fluorometric immunoassays.
Journal of immunological methods 2007;319(1-2):133-43.
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2006: Weets I; Truyen I; Verschraegen I; Van der Auwera B; De Schepper J; Dorchy H; Lebrethon M-C; Van Gaal L; Van Rooy P; Pipeleers D G; Gorus F K;
Sex- and season-dependent differences in C-peptide levels at diagnosis of immune-mediated type 1 diabetes.
Diabetologia 2006;49(6):1158-62.
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2005: Truyen I; De Pauw P; Jørgensen P N; Van Schravendijk C; Ubani O; Decochez K; Vandemeulebroucke E; Weets I; Mao R; Pipeleers D G; Gorus F K;
Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes.
Diabetologia 2005;48(11):2322-9.
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2005: van Kampen Corine A; van de Linde Pieter; Duinkerken Gaby; van Schip Jolien J; Roelen Dave L; Keymeulen Bart; Pipeleers Daniel G; Claas Frans H J; Roep Bart O
Alloreactivity against repeated HLA mismatches of sequential islet grafts transplanted in non-uremic type 1 diabetes patients.
Transplantation 2005;80(1):118-26.
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2005: Bouwman Lee H; Ling Zhidong; Duinkerken Gaby; Pipeleers Daniel G; Roep Bart O
HLA incompatibility and immunogenicity of human pancreatic islet preparations cocultured with blood cells of healthy donors.
Human immunology 2005;66(5):494-500.
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2005: Decochez K; Truyen I; van der Auwera B; Weets I; Vandemeulebroucke E; de Leeuw I H; Keymeulen B; Mathieu C; Rottiers R; Pipeleers D G; Gorus F K;
Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes.
Diabetologia 2005;48(4):687-94.
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2005: Borromeo Cecilia M; Pottier Xavier; In't Veld Peter A; Pipeleers-Marichal Miriam A; Kaufman Leonard; Pipeleers Daniel G; Van Schravendijk Christiaan F
Heterogeneity in distribution of amyloid-positive islets in type-2 diabetic patients.
Virchows Archiv : an international journal of pathology 2005;446(3):232-8.
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2005: Rescan Claude; Le Bras Stéphanie; Lefebvre Véronique H; Frandsen Ulrik; Klein Tino; Foschi Marco; Pipeleers Daniel G; Scharfmann Raphael; Madsen Ole D; Heimberg Harry
EGF-induced proliferation of adult human pancreatic duct cells is mediated by the MEK/ERK cascade.
Laboratory investigation; a journal of technical methods and pathology 2005;85(1):65-74.
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2004: Weets I; Kaufman L; Van der Auwera B; Crenier L; Rooman R P A; De Block C; Casteels K; Weber E; Coeckelberghs M; Laron Z; Pipeleers D G; Gorus F K;
Seasonality in clinical onset of type 1 diabetes in belgian patients above the age of 10 is restricted to HLA-DQ2/DQ8-negative males, which explains the male to female excess in incidence.
Diabetologia 2004;47(4):614-21.
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2004: Gorus F K; Weets I; Couck P; Pipeleers D G;
Epidemiology of type 1 and type 2 diabetes. The added value of diabetes registries for conducting clinical studies: the Belgian paradigm.
Acta clinica Belgica 2004;59(1):1-13.
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2002: Decochez K; De Leeuw I H; Keymeulen B; Mathieu C; Rottiers R; Weets I; Vandemeulebroucke E; Truyen I; Kaufman L; Schuit F C; Pipeleers D G; Gorus F K;
IA-2 autoantibodies predict impending type I diabetes in siblings of patients.
Diabetologia 2002;45(12):1658-66.
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2002: Löbner Kristian; Steinbrenner Holger; Roberts Graham A; Ling Zhidong; Huang Guo-Cai; Piquer Sandra; Pipeleers Daniel G; Seissler Jochen; Christie Michael R
Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life.
Diabetes 2002;51(10):2982-8.
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2002: Cnop Miriam; Hannaert Jean Claude; Grupping Annick Y; Pipeleers Daniel G
Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification.
Endocrinology 2002;143(9):3449-53.
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2002: Weets Ilse; De Leeuw Ivo H; Du Caju Marc V L; Rooman Raoul; Keymeulen Bart; Mathieu Chantal; Rottiers Raoul; Daubresse Jean-Claude; Rocour-Brumioul Danielle; Pipeleers Daniel G; Gorus Frans K;
The incidence of type 1 diabetes in the age group 0-39 years has not increased in Antwerp (Belgium) between 1989 and 2000: evidence for earlier disease manifestation.
Diabetes care 2002;25(5):840-6.
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2002: Cnop Miriam; Hannaert Jean Claude; Pipeleers Daniel G
Troglitazone does not protect rat pancreatic beta cells against free fatty acid-induced cytotoxicity.
Biochemical pharmacology 2002;63(7):1281-5.
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2002: Gorus F K; Weets I; Pipeleers D G
To: T.J. Wilkin (2001) The accelerator hypothesis: weight gain as the missing link between Type I and Type II diabetes. Diabetologia 44: 914-921.
Diabetologia 2002;45(2):288-9; author reply 289.
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2002: Van de Casteele Mark; Kefas Benjamin Ate; Ling Zhidong; Heimberg Harry; Pipeleers Daniel G
Specific expression of Bax-omega in pancreatic beta-cells is down-regulated by cytokines before the onset of apoptosis.
Endocrinology 2002;143(1):320-6.
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2001: Gorus F K; Pipeleers D G;
Prospects for predicting and stopping the development of type 1 of diabetes.
Best practice & research. Clinical endocrinology & metabolism 2001;15(3):371-89.
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2001: Cnop M; Hannaert J C; Hoorens A; Eizirik D L; Pipeleers D G
Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.
Diabetes 2001;50(8):1771-7.
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2001: Ling Z; Wu D; Zambre Y; Flamez D; Drucker D J; Pipeleers D G; Schuit F C
Glucagon-like peptide 1 receptor signaling influences topography of islet cells in mice.
Virchows Archiv : an international journal of pathology 2001;438(4):382-7.
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2001: Schuit F C; Huypens P; Heimberg H; Pipeleers D G
Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus.
Diabetes 2001;50(1):1-11.
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2000: Vreugdenhil G R; Schloot N C; Hoorens A; Rongen C; Pipeleers D G; Melchers W J; Roep B O; Galama J M
Acute onset of type I diabetes mellitus after severe echovirus 9 infection: putative pathogenic pathways.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;31(4):1025-31.
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2000: Decochez K; Keymeulen B; Somers G; Dorchy H; De Leeuw I H; Mathieu C; Rottiers R; Winnock F; ver Elst K; Weets I; Kaufman L; Pipeleers D G; Rottiers R;
Use of an islet cell antibody assay to identify type 1 diabetic patients with rapid decrease in C-peptide levels after clinical onset. Belgian Diabetes Registry.
Diabetes care 2000;23(8):1072-8.
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2000: Decochez K; Tits J; Coolens J L; Van Gaal L; Krzentowski G; Winnock F; Anckaert E; Weets I; Pipeleers D G; Gorus F K
High frequency of persisting or increasing islet-specific autoantibody levels after diagnosis of type 1 diabetes presenting before 40 years of age. The Belgian Diabetes Registry.
Diabetes care 2000;23(6):838-44.
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2000: Ling Z; Van de Casteele M; Eizirik D L; Pipeleers D G
Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis.
Diabetes 2000;49(3):340-5.
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2000: Smismans A; Eizirik D L; Pipeleers D G
Interleukin-1beta induces ornithine decarboxylase activity in insulin-producing cells.
Cytokine 2000;12(1):49-54.
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1999: Chen M C; Schuit F; Pipeleers D G; Eizirik D L
IL-1beta induces serine protease inhibitor 3 (SPI-3) gene expression in rat pancreatic beta-cells. Detection by differential display of messenger RNA.
Cytokine 1999;11(11):856-62.
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1999: Hostens K; Pavlovic D; Zambre Y; Ling Z; Van Schravendijk C; Eizirik D L; Pipeleers D G
Exposure of human islets to cytokines can result in disproportionately elevated proinsulin release.
The Journal of clinical investigation 1999;104(1):67-72.
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1999: Flodström M; Chen M C; Smismans A; Schuit F; Pipeleers D G; Eizirik D L
Interleukin 1beta increases arginine accumulation and activates the citrulline-NO cycle in rat pancreatic beta cells.
Cytokine 1999;11(6):400-7.
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1999: Zambre Y; Ling Z; Chen M C; Hou X; Woon C W; Culler M; Taylor J E; Coy D H; Van Schravendijk C; Schuit F; Pipeleers D G; Eizirik D L
Inhibition of human pancreatic islet insulin release by receptor-selective somatostatin analogs directed to somatostatin receptor subtype 5.
Biochemical pharmacology 1999;57(10):1159-64.
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1999: Hao W; Daniels T; Pipeleers D G; Smismans A; Reijonen H; Nepom G T; Lernmark A
Radioimmunoassay for glutamic acid decarboxylase-65.
Diabetes technology & therapeutics 1999;1(1):13-20.
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1998: Bouwens L; Pipeleers D G
Extra-insular beta cells associated with ductules are frequent in adult human pancreas.
Diabetologia 1998;41(6):629-33.
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1998: Keymeulen B; Ling Z; Gorus F K; Delvaux G; Bouwens L; Grupping A; Hendrieckx C; Pipeleers-Marichal M; Van Schravendijk C; Salmela K; Pipeleers D G
Implantation of standardized beta-cell grafts in a liver segment of IDDM patients: graft and recipients characteristics in two cases of insulin-independence under maintenance immunosuppression for prior kidney graft.
Diabetologia 1998;41(4):452-9.
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1998: Ling Z; Chen M C; Smismans A; Pavlovic D; Schuit F; Eizirik D L; Pipeleers D G
Intercellular differences in interleukin 1beta-induced suppression of insulin synthesis and stimulation of noninsulin protein synthesis by rat pancreatic beta-cells.
Endocrinology 1998;139(4):1540-5.
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1998: Gorus F K; Vandewalle C L; Winnock F; Lebleu F; Keymeulen B; Van der Auwera B; Falorni A; Dorchy H; Féry F; Pipeleers D G
Increased prevalence of abnormal immunoglobulin M, G, and A concentrations at clinical onset of insulin-dependent diabetes mellitus: a registry-based study. The Belgian Diabetes Registry.
Pancreas 1998;16(1):50-9.
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1998: Lefebvre V H; Otonkoski T; Ustinov J; Huotari M A; Pipeleers D G; Bouwens L
Culture of adult human islet preparations with hepatocyte growth factor and 804G matrix is mitogenic for duct cells but not for beta-cells.
Diabetes 1998;47(1):134-7.
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1997: Grupping A Y; Cnop M; Van Schravendijk C F; Hannaert J C; Van Berkel T J; Pipeleers D G
Low density lipoprotein binding and uptake by human and rat islet beta cells.
Endocrinology 1997;138(10):4064-8.
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1997: Vandewalle C L; Coeckelberghs M I; De Leeuw I H; Du Caju M V; Schuit F C; Pipeleers D G; Gorus F K
Epidemiology, clinical aspects, and biology of IDDM patients under age 40 years. Comparison of data from Antwerp with complete ascertainment with data from Belgium with 40% ascertainment. The Belgian Diabetes Registry.
Diabetes care 1997;20(10):1556-61.
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1997: Vandewalle C L; Falorni A; Lernmark A; Goubert P; Dorchy H; Coucke W; Semakula C; Van der Auwera B; Kaufman L; Schuit F C; Pipeleers D G; Gorus F K
Associations of GAD65- and IA-2- autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings. The Belgian Diabetes Registry.
Diabetes care 1997;20(10):1547-52.
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1997: Sandler S; Andersson A; Eizirik D L; Hellerström C; Espevik T; Kulseng B; Thu B; Pipeleers D G; Skjåk-Braek G
Assessment of insulin secretion in vitro from microencapsulated fetal porcine islet-like cell clusters and rat, mouse, and human pancreatic islets.
Transplantation 1997;63(12):1712-8.
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1997: Delaney C A; Pavlovic D; Hoorens A; Pipeleers D G; Eizirik D L
Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells.
Endocrinology 1997;138(6):2610-4.
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1997: Gorus F K; Goubert P; Semakula C; Vandewalle C L; De Schepper J; Scheen A; Christie M R; Pipeleers D G
IA-2-autoantibodies complement GAD65-autoantibodies in new-onset IDDM patients and help predict impending diabetes in their siblings. The Belgian Diabetes Registry.
Diabetologia 1997;40(1):95-9.
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1996: Ling Z; Pipeleers D G
Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation.
The Journal of clinical investigation 1996;98(12):2805-12.
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1996: Tyrberg B; Eizirik D L; Hellerström C; Pipeleers D G; Andersson A
Human pancreatic beta-cell deoxyribonucleic acid-synthesis in islet grafts decreases with increasing organ donor age but increases in response to glucose stimulation in vitro.
Endocrinology 1996;137(12):5694-9.
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1996: Keymeulen B; Korbutt G; De Paepe M; Gorus F; Klöppel G; Pipeleers D G
Long-term metabolic control by rat islet grafts depends on the composition of the implant.
Diabetes 1996;45(12):1814-21.
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1996: Ling Z; Kiekens R; Mahler T; Schuit F C; Pipeleers-Marichal M; Sener A; Kloppel G; Malaisse W J; Pipeleers D G
Effects of chronically elevated glucose levels on the functional properties of rat pancreatic beta-cells.
Diabetes 1996;45(12):1774-82.
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1996: Andersson A; Eizirik D L; Bremer C; Johnson R C; Pipeleers D G; Hellerström C
Structure and function of macroencapsulated human and rodent pancreatic islets transplanted into nude mice.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1996;28(6):306-9.
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1996: Semakula C; Vandewalle C L; Van Schravendijk C F; Sodoyez J C; Schuit F C; Foriers A; Falorni A; Craen M; Decraene P; Pipeleers D G; Gorus F K
Abnormal circulating pancreatic enzyme activities in more than twenty-five percent of recent-onset insulin-dependent diabetic patients: association of hyperlipasemia with high-titer islet cell antibodies. Belgian Diabetes Registry.
Pancreas 1996;12(4):321-33.
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1996: Eizirik D L; Delaney C A; Green M H; Cunningham J M; Thorpe J R; Pipeleers D G; Hellerström C; Green I C
Nitric oxide donors decrease the function and survival of human pancreatic islets.
Molecular and cellular endocrinology 1996;118(1-2):71-83.
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1996: Myrsén U; Keymeulen B; Pipeleers D G; Sundler F
Beta cells are important for islet innervation: evidence from purified rat islet-cell grafts.
Diabetologia 1996;39(1):54-9.
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1995: Welsh N; Margulis B; Borg L A; Wiklund H J; Saldeen J; Flodström M; Mello M A; Andersson A; Pipeleers D G; Hellerström C
Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus.
Molecular medicine (Cambridge, Mass.) 1995;1(7):806-20.
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1995: Jansson L; Eizirik D L; Pipeleers D G; Borg L A; Hellerström C; Andersson A
Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice.
The Journal of clinical investigation 1995;96(2):721-6.
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1995: Vandewalle C L; Falorni A; Svanholm S; Lernmark A; Pipeleers D G; Gorus F K
High diagnostic sensitivity of glutamate decarboxylase autoantibodies in insulin-dependent diabetes mellitus with clinical onset between age 20 and 40 years. The Belgian Diabetes Registry.
The Journal of clinical endocrinology and metabolism 1995;80(3):846-51.
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1994: Bouwens L; Wang R N; De Blay E; Pipeleers D G; Klöppel G
Cytokeratins as markers of ductal cell differentiation and islet neogenesis in the neonatal rat pancreas.
Diabetes 1994;43(11):1279-83.
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1994: Van Schravendijk C F; Kiekens R; Heylen L; Pipeleers D G
Amino-acid responsiveness in beta cell subpopulations with different sensitivity to glucose.
Biochemical and biophysical research communications 1994;204(2):490-7.
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1994: Eizirik D L; Pipeleers D G; Ling Z; Welsh N; Hellerström C; Andersson A
Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9253-6.
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1994: Hellman B; Gylfe E; Bergsten P; Grapengiesser E; Lund P E; Berts A; Tengholm A; Pipeleers D G; Ling Z
Glucose induces oscillatory Ca2+ signalling and insulin release in human pancreatic beta cells.
Diabetologia 1994;37 Suppl 2():S11-20.
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1994: Korbutt G S; Pipeleers D G
Cold-preservation of pancreatic beta cells.
Cell transplantation 1994;3(4):291-7.
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1994: Ling Z; Pipeleers D G
Preservation of glucose-responsive islet beta-cells during serum-free culture.
Endocrinology 1994;134(6):2614-21.
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1994: Gorus F K; Vandewalle C L; Dorchy H; Van Crombrugge P; Schuit F C; Pipeleers D G
Influence of age on the associations among insulin autoantibodies, islet cell antibodies, and HLA DAQ1*0301-DQB1*0302 in siblings of patients with type 1 (insulin-dependent) diabetes mellitus. Belgian Diabetes Registry.
The Journal of clinical endocrinology and metabolism 1994;78(5):1172-8.
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1994: Eizirik D L; Sandler S; Welsh N; Cetkovic-Cvrlje M; Nieman A; Geller D A; Pipeleers D G; Bendtzen K; Hellerström C
Cytokines suppress human islet function irrespective of their effects on nitric oxide generation.
The Journal of clinical investigation 1994;93(5):1968-74.
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1994: Andersson A; Eizirik D L; Hellerström C; Johnson R C; Pipeleers D G
Morphology of encapsulated human pancreatic islets transplanted into nude mice.
Transplantation proceedings 1994;26(2):802-3.
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1993: Vandewalle C L; Decraene T; Schuit F C; De Leeuw I H; Pipeleers D G; Gorus F K
Insulin autoantibodies and high titre islet cell antibodies are preferentially associated with the HLA DQA1*0301-DQB1*0302 haplotype at clinical type 1 (insulin-dependent) diabetes mellitus before age 10 years, but not at onset between age 10 and 40 years. The Belgian Diabetes Registry.
Diabetologia 1993;36(11):1155-62.
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1993: Korbutt G S; Pipeleers D G
Rat pancreas preparation for cold storage and subsequent islet cell isolation.
Transplantation 1993;56(3):500-3.
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1993: Keymeulen B; Vetri M; Gorus F; Vanbrabandt B; Pipeleers D G
The effect of insulin treatment on function of intraportally grafted islets in streptozotocin-diabetic rats.
Transplantation 1993;56(1):60-4.
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1993: Ling Z; In't Veld P A; Pipeleers D G
Interaction of interleukin-1 with islet beta-cells. Distinction between indirect, aspecific cytotoxicity and direct, specific functional suppression.
Diabetes 1993;42(1):56-65.
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1992: Gorus F K; Sodoyez J C; Pipeleers D G; Keymeulen B; Foriers A; Van Schravendijk C F
Detection of autoantibodies against islet amyloid polypeptide in human serum. Lack of association with type 1 (insulin-dependent) diabetes mellitus, or with conditions favouring amyloid deposition in islets. The Belgian Diabetes Registry.
Diabetologia 1992;35(11):1080-6.
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1992: Van Schravendijk C F; Kiekens R; Pipeleers D G
Pancreatic beta cell heterogeneity in glucose-induced insulin secretion.
The Journal of biological chemistry 1992;267(30):21344-8.
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1992: Keymeulen B; Teng H; Vetri M; Gorus F; In't Veld P; Pipeleers D G
Effect of donor islet mass on metabolic normalization in streptozotocin-diabetic rats.
Diabetologia 1992;35(8):719-24.
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1992: Pipeleers D G
Heterogeneity in pancreatic beta-cell population.
Diabetes 1992;41(7):777-81.
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1992: Korbutt G S; Pipeleers D G
Cold storage of rat pancreas before purification of islet beta-cells.
Diabetes 1992;41(3):299-307.
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1991: Schuit F C; Kiekens R; Pipeleers D G
Measuring the balance between insulin synthesis and insulin release.
Biochemical and biophysical research communications 1991;178(3):1182-7.
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1991: Pipeleers-Marichal M; Ling Z D; Teng H; Pipeleers D G
Transplantation of purified islet cells in diabetic rats. III. Immunosuppressive effect of cyclosporin.
Diabetes 1991;40(7):931-8.
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1991: Pipeleers D G; Pipeleers-Marichal M; Vanbrabandt B; Duys S
Transplantation of purified islet cells in diabetic rats. II. Immunogenicity of allografted islet beta-cells.
Diabetes 1991;40(7):920-30.
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1991: Pipeleers D G; Pipeleers-Marichal M; Hannaert J C; Berghmans M; In't Veld P A; Rozing J; Van de Winkel M; Gepts W
Transplantation of purified islet cells in diabetic rats. I. Standardization of islet cell grafts.
Diabetes 1991;40(7):908-19.
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1990: Van Schravendijk C F; Heylen L; Van den Brande J L; Pipeleers D G
Direct effect of insulin and insulin-like growth factor-I on the secretory activity of rat pancreatic beta cells.
Diabetologia 1990;33(11):649-53.
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1990: De Vroede M A; In' t Veld P A; Pipeleers D G
Deoxyribonucleic acid synthesis in cultured adult rat pancreatic B cells.
Endocrinology 1990;127(3):1510-6.
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1990: Christie M R; Pipeleers D G; Lernmark A; Baekkeskov S
Cellular and subcellular localization of an Mr 64,000 protein autoantigen in insulin-dependent diabetes.
The Journal of biological chemistry 1990;265(1):376-81.
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1988: In't Veld P A; Pipeleers D G
In situ analysis of pancreatic islets in rats developing diabetes. Appearance of nonendocrine cells with surface MHC class II antigens and cytoplasmic insulin immunoreactivity.
The Journal of clinical investigation 1988;82(3):1123-8.
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1988: Gorus F K; Schuit F C; In't Veld P A; Gepts W; Pipeleers D G
Interaction of sulfonylureas with pancreatic beta-cells. A study with glyburide.
Diabetes 1988;37(8):1090-5.
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1988: Schuit F C; In't Veld P A; Pipeleers D G
Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(11):3865-9.
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1987: Van Schravendijk C F; Foriers A; Van den Brande J L; Pipeleers D G
Evidence for the presence of type I insulin-like growth factor receptors on rat pancreatic A and B cells.
Endocrinology 1987;121(5):1784-8.
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1986: In't Veld P A; Pipeleers D G; Gepts W
Glucose alters configuration of gap junctions between pancreatic islet cells.
The American journal of physiology 1986;251(2 Pt 1):C191-6.
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1986: Van Schravendijk C F; Hooghe-Peters E L; Van den Brande J L; Pipeleers D G
Receptors for insulin-like growth factors and insulin on murine fetal cortical brain cells.
Biochemical and biophysical research communications 1986;135(1):228-38.
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1985: Van Schravendijk C F; Foriers A; Hooghe-Peters E L; Rogiers V; De Meyts P; Sodoyez J C; Pipeleers D G
Pancreatic hormone receptors on islet cells.
Endocrinology 1985;117(3):841-8.
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1985: Pipeleers D G; Schuit F C; in't Veld P A; Maes E; Hooghe-Peters E L; Van de Winkel M; Gepts W
Interplay of nutrients and hormones in the regulation of insulin release.
Endocrinology 1985;117(3):824-33.
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1985: Pipeleers D G; Schuit F C; Van Schravendijk C F; Van de Winkel M
Interplay of nutrients and hormones in the regulation of glucagon release.
Endocrinology 1985;117(3):817-23.
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1985: Pipeleers D G; in't Veld P A; Van de Winkel M; Maes E; Schuit F C; Gepts W
A new in vitro model for the study of pancreatic A and B cells.
Endocrinology 1985;117(3):806-16.
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1984: Sener A; Van Schaftingen E; Van de Winkel M; Pipeleers D G; Malaisse-Lagae F; Malaisse W J; Hers H G
Effects of glucose and glucagon on the fructose 2,6-bisphosphate content of pancreatic islets and purified pancreatic B-cells. A comparison with isolated hepatocytes.
The Biochemical journal 1984;221(3):759-64.
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1984: Van Schravendijk C F; Hooghe-Peters E L; De Meyts P; Pipeleers D G
Identification and characterization of insulin receptors on foetal-mouse brain-cortical cells.
The Biochemical journal 1984;220(1):165-72.
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1984: in't Veld P A; Pipeleers D G; Gepts W
Evidence against the presence of tight junctions in normal endocrine pancreas.
Diabetes 1984;33(1):101-4.
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1981: Pipeleers D G; Pipeleers-Marichal M A
A method for the purification of single A, B and D cells and for the isolation of coupled cells from isolated rat islets.
Diabetologia 1981;20(6):654-63.
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