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Claudio Pisano

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Disorders

Ovarian Neoplasms

Concepts & Ideas

Structure-Activity Relationship

Procedures

Physiology

Genes & Molecular Sequences

Molecular Structure

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Publications

TOP 3
Giuliana Cassinelli; D Cominetti; Enrica Favini; Cinzia Lanzi; S Penco; Giovanna Petrangolini; Claudio Pisano; Monica Tortoreto; I Vlodavsky; Nadia Zaffaroni; Franco Zunino
Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models.
Daniela Meco; Valentina Patriarca; Filomena Pierri; Claudio Pisano; Federica Bucci; Gabriella Cusano; Angela Maria Di Francesco; Anna Rita Torella; Riccardo Riccardi
Preclinical evaluation of the novel 7-substituted camptothecin Namitecan (ST1968) in paediatric tumour models.
Domenico Alloatti; Elena Badaloni; Massimo Castorina; Giuseppe Giannini; Claudio Pisano; Loredana Vesci; Walter Cabri
Camptothecins in tumor homing via an RGD sequence mimetic.

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All Publications

2013: Giuliana Cassinelli; D Cominetti; Enrica Favini; Cinzia Lanzi; S Penco; Giovanna Petrangolini; Claudio Pisano; Monica Tortoreto; I Vlodavsky; Nadia Zaffaroni; Franco Zunino
Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models.
Biochemical pharmacology 2013;85(10):1424-32.
2012: Daniela Meco; Valentina Patriarca; Filomena Pierri; Claudio Pisano; Federica Bucci; Gabriella Cusano; Angela Maria Di Francesco; Anna Rita Torella; Riccardo Riccardi
Preclinical evaluation of the novel 7-substituted camptothecin Namitecan (ST1968) in paediatric tumour models.
Cancer chemotherapy and pharmacology 2012;70(6):811-22.
2012: Domenico Alloatti; Elena Badaloni; Massimo Castorina; Giuseppe Giannini; Claudio Pisano; Loredana Vesci; Walter Cabri
Camptothecins in tumor homing via an RGD sequence mimetic.
Bioorganic & medicinal chemistry letters 2012;22(20):6509-12.
2012: Sabrina Dallavalle; Claudio Pisano; Franco Zunino
Development and therapeutic impact of HDAC6-selective inhibitors.
Biochemical pharmacology 2012;84(6):756-65.
2012: Israel Vlodavsky; Phillip Beckhove; Neta Ilan; Immanuel Lerner; Amichay Meirovitz; Claudio Pisano; Michael Elkin
Significance of heparanase in cancer and inflammation.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2012;5(2):115-32.
2012: Angela Maria Di Francesco; Maurizio D'Incalci; Daniela Meco; Filomena Pierri; Claudio Pisano; Giuseppe Barone; Gabriella Cusano; Anna Rita Torella; Paolo Ubezio; Riccardo Riccardi
Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models.
Investigational new drugs 2012;30(4):1319-30.
2012: Giuliana Cassinelli; Denis Cominetti; Michelandrea De Cesare; Angela Maria Di Francesco; Cinzia Lanzi; Daniela Meco; Augusto Orlandi; Daniela Passeri; Giovanna Petrangolini; Claudio Pisano; Riccardo Riccardi; Monica Tortoreto; Nadia Zaffaroni; Valentina Zuco; Federica Bucci; Franco Zunino
The curative efficacy of namitecan (ST1968) in preclinical models of pediatric sarcoma is associated with antiangiogenic effects.
Biochemical pharmacology 2012;84(2):163-71.
2012: Alberto Bargiotti; Walter Cabri; Massimo Castorina; Maria Luisa Cervoni; Andrea Ciacci; Sabrina Dallavalle; Michelandrea De Cesare; Grazia Gallo; Giuseppe Giannini; Chiara Giommarelli; Lucio Merlini; Ferdinando Maria Milazzo; Loana Musso; Sergio Penco; Claudio Pisano; Loredana Vesci; Valentina Zuco; Marcella Barbarino; Franco Zunino
Isoxazolo(aza)naphthoquinones: a new class of cytotoxic Hsp90 inhibitors.
European journal of medicinal chemistry 2012;53():64-75.
2012: Giuseppe Giannini; Mario Berardino Guglielmi; Lucio Merlini; Raffaella Nannei; Claudio Pisano; Gianandrea Quattrociocchi; Loredana Vesci; Domenico Alloatti; Gianfranco Battistuzzi; Tiziana Brunetti; Federica Bucci; Maria Grazia Cima; Raffaella Cincinelli; Sabrina Dallavalle; Rosanna Foderà; Walter Cabri
New retinoid derivatives as back-ups of Adarotene.
Bioorganic & medicinal chemistry 2012;20(7):2405-15.
2012: Fabrizio Dal Piaz; Nunziatina De Tommasi; Adriana Romano; Rokia SANOGO; Maria Antonietta Belisario; Giuseppe Bifulco; Dario Gallotta; Maria Josefine Gualtieri; Nicola Malafronte; Claudio Pisano
Structural characterization of tetranortriterpenes from Pseudrocedrela kotschyi and Trichilia emetica and study of their activity towards the chaperone Hsp90.
Phytochemistry 2012;75():78-89.
2011: Sandro Pignata; Claudio Pisano; W Rasch; Giovanni Scambia; Roberto Sorio; F Amant; Enrico Breda; L Cannella; K Hernes; K Leunen; Domenica Lorusso; I Vergote
A phase I-II study of elacytarabine (CP-4055) in the treatment of patients with ovarian cancer resistant or refractory to platinum therapy.
Cancer chemotherapy and pharmacology 2011;68(5):1347-53.
2011: Itay Shafat; Monica Tortoreto; Israel Vlodavsky; Myriam Weyl Ben Arush; Giuliana Cassinelli; Neta Ilan; Josephine Issakov; Cinzia Lanzi; Isaac Meller; Inna Naroditsky; Claudio Pisano; Franco Zunino
Pre-clinical and clinical significance of heparanase in Ewing's sarcoma.
Journal of cellular and molecular medicine 2011;15(9):1857-64.
2011: Stefano Greggi; Giorgia Mangili; Cono Scaffa; Felice Scala; Simona Losito; Francesco Iodice; Claudio Pisano; Serena Montoli; Riccardo Viganò; Giuseppe Pirozzi; Diana Giannarelli
Uterine papillary serous, clear cell, and poorly differentiated endometrioid carcinomas: a comparative study.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2011;21(4):661-7.
2010: Alma Dal Pozzo; Emiliano Esposito; Minghong Ni; Laura Muzi; Claudio Pisano; Federica Bucci; Loredana Vesci; Massimo Castorina; Sergio Penco
Conjugates of a novel 7-substituted camptothecin with RGD-peptides as α(v)β₃ integrin ligands: An approach to tumor-targeted therapy.
Bioconjugate chemistry 2010;21(11):1956-67.
2010: Loana Musso; Sabrina Dallavalle; Lucio Merlini; Adriana Bava; Gianluca Nasini; Sergio Penco; Giuseppe Giannini; Chiara Giommarelli; Andrea De Cesare; Valentina Zuco; Loredana Vesci; Claudio Pisano; Massimo Castorina; Ferdinando Milazzo; Maria Luisa Cervoni; Fabrizio Dal Piaz; Nunziatina De Tommasi; Franco Zunino
Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors.
Bioorganic & medicinal chemistry 2010;18(16):6031-43.
2010: Claudio Pisano; Loredana Vesci; Ferdinando Maria Milazzo; Mario Berardino Guglielmi; Rosanna Foderà; Marcella Barbarino; Maurizio D'Incalci; Massimo Zucchetti; Giovanna Petrangolini; Monica Tortoreto; Paola Perego; Valentina Zuco; Augusto Orlandi; Daniela Passeri; Paolo Carminati; Claudio Cavazza; Franco Zunino
Metabolic approach to the enhancement of antitumor effect of chemotherapy: a key role of acetyl-L-carnitine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(15):3944-53.
2010: Fabrizio Dal Piaz; Alessandra Tosco; Daniela Eletto; Anna Lisa Piccinelli; Ornella Moltedo; Silvia Franceschelli; Gianluca Sbardella; Paolo Remondelli; Luca Rastrelli; Loredana Vesci; Claudio Pisano; Nunziatina De Tommasi
The identification of a novel natural activator of p300 histone acetyltranferase provides new insights into the modulation mechanism of this enzyme.
Chembiochem : a European journal of chemical biology 2010;11(6):818-27.
2010: Stefano Greggi; Simona Losito; Claudio Pisano; Sonia Desicato; Cono Scaffa
Malignant melanoma of the vagina: report of two cases and review of the literature.
International surgery 2010;95(2):120-5.
2010: Chiara Giommarelli; Valentina Zuco; Enrica Favini; Claudio Pisano; Fabrizio Dal Piaz; Nunziatina De Tommasi; Franco Zunino
The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition.
Cellular and molecular life sciences : CMLS 2010;67(6):995-1004.
2010: Valentina Zuco; Rosanna Supino; Enrica Favini; Monica Tortoreto; Raffaella Cincinelli; Anna Cleta Croce; Federica Bucci; Claudio Pisano; Franco Zunino
Efficacy of ST1968 (namitecan) on a topotecan-resistant squamous cell carcinoma.
Biochemical pharmacology 2010;79(4):535-41.
2010: Roberta Frapolli; Massimo Zucchetti; Cristiana Sessa; Silvia Marsoni; Lucia Viganò; Alberta Locatelli; Eliana Rulli; Anna Compagnoni; Ezia Bello; Claudio Pisano; Paolo Carminati; Maurizio D'Incalci
Clinical pharmacokinetics of the new oral camptothecin gimatecan: the inter-patient variability is related to alpha1-acid glycoprotein plasma levels.
European journal of cancer (Oxford, England : 1990) 2010;46(3):505-16.
2010: Claudia Marchetti; Claudio Pisano; Gaetano Facchini; Giovanni Salvatore Bruni; Francesca Paola Magazzino; Simona Losito; Sandro Pignata
First-line treatment of advanced ovarian cancer: current research and perspectives.
Expert review of anticancer therapy 2010;10(1):47-60.
2010: Alma Dal Pozzo; Ming-Hong Ni; Emiliano Esposito; Sabrina Dallavalle; Loana Musso; Alberto Bargiotti; Claudio Pisano; Loredana Vesci; Federica Bucci; Massimo Castorina; Rosanna Foderà; Giuseppe Giannini; Concetta Aulicino; Sergio Penco
Novel tumor-targeted RGD peptide-camptothecin conjugates: synthesis and biological evaluation.
Bioorganic & medicinal chemistry 2010;18(1):64-72.
2010: Sandro Pignata; Eric Pujade Lauraine; Andreas du Bois; Claudio Pisano
Pegylated liposomal doxorubicin combined with carboplatin: a rational treatment choice for advanced ovarian cancer.
Critical reviews in oncology/hematology 2010;73(1):23-30.
2009: Sandro Pignata; Gabriella Ferrandina; Giovanna Scarfone; Paolo Scollo; Franco Odicino; Gennaro Cormio; Dionyssios Katsaros; Luigi Frigerio; Liliana Mereu; Fabio Ghezzi; Luigi Manzione; Rossella Lauria; Enrico Breda; Desiderio Gueli Alletti; Michela Ballardini; Alessandra Vernaglia; Roberto Sorio; Salvatore Tumolo; Pietro Musso; Giovanna Magni; Claudio Pisano; Alessandro Morabito
Poor outcome of elderly patients with platinum-sensitive recurrent ovarian cancer: results from the SOCRATES retrospective study.
Critical reviews in oncology/hematology 2009;71(3):233-41.
2009: Giuseppe Giannini; Mauro Marzi; Maria Di Marzo; Gianfranco Battistuzzi; Riccardo Pezzi; Tiziana Brunetti; Walter Cabri; Loredana Vesci; Claudio Pisano
Exploring bis-(indolyl)methane moiety as an alternative and innovative CAP group in the design of histone deacetylase (HDAC) inhibitors.
Bioorganic & medicinal chemistry letters 2009;19(10):2840-3.
2009: Sabrina Dallavalle; Raffaella Cincinelli; Raffaella Nannei; Lucio Merlini; Gabriella Morini; Sergio Penco; Claudio Pisano; Loredana Vesci; Marcella Barbarino; Valentina Zuco; Michelandrea De Cesare; Franco Zunino
Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors.
European journal of medicinal chemistry 2009;44(5):1900-12.
2009: Giuseppe Giannini; Mauro Marzi; Riccardo Pezzi; Tiziana Brunetti; Gianfranco Battistuzzi; Maria Di Marzo; Walter Cabri; Loredana Vesci; Claudio Pisano
N-Hydroxy-(4-oxime)-cinnamide: a versatile scaffold for the synthesis of novel histone deacetylase [correction of deacetilase] (HDAC) inhibitors.
Bioorganic & medicinal chemistry letters 2009;19(8):2346-9.
2008: Daniele Simoni; LUISA-CARLOTA LÓPEZ-CARA; Riccardo Baruchello; Riccardo Rondanin; Giuseppina Grisolia; Marco Eleopra; Michele Rizzi; Manlio Tolomeo; Giuseppe Giannini; Domenico Alloatti; Massimo Castorina; Marcella Marcellini; Claudio Pisano
Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity.
Journal of medicinal chemistry 2008;51(19):6211-5.
2008: Claudia Valli; Gabriela Paroni; Angela Maria Di Francesco; Riccardo Riccardi; Michele Tavecchio; Eugenio Erba; Andrea Boldetti; Maurizio Gianni'; Maddalena Fratelli; Claudio Pisano; Lucio Merlini; Antonio Antoccia; Chiara Cenciarelli; Mineko Terao; Enrico Garattini
Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity.
Molecular cancer therapeutics 2008;7(9):2941-54.
2008: Claudio Pisano; Michelandrea De Cesare; Giovanni Luca Beretta; Valentina Zuco; Graziella Pratesi; Sergio Penco; Loredana Vesci; Rosanna Foderà; Fabiana Fosca Ferrara; Mario Berardino Guglielmi; Paolo Carminati; Sabrina Dallavalle; Gabriella Morini; Lucio Merlini; Augusto Orlandi; Franco Zunino
Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.
Molecular cancer therapeutics 2008;7(7):2051-9.
2008: Claudio Pisano; Valentina Zuco; Michelandrea De Cesare; Valentina Benedetti; Loredana Vesci; Rosanna Foderà; Federica Bucci; Concetta Aulicino; Sergio Penco; Paolo Carminati; Franco Zunino
Intracellular accumulation and DNA damage persistence as determinants of human squamous cell carcinoma hypersensitivity to the novel camptothecin ST1968.
European journal of cancer (Oxford, England : 1990) 2008;44(9):1332-40.
2008: Giuseppe Giannini; MAURO MARZI; Walter Cabri; Elena Marastoni; Gianfranco Battistuzzi; Loredana Vesci; Claudio Pisano; Giovanni Luca Beretta; Michelandrea De Cesare; Franco Zunino
E-ring-modified 7-oxyiminomethyl camptothecins: Synthesis and preliminary in vitro and in vivo biological evaluation.
Bioorganic & medicinal chemistry letters 2008;18(9):2910-5.
2008: Chiara Cenciarelli; Caterina Tanzarella; Ilio Vitale; Claudio Pisano; Pasqualina Crateri; Stefania Meschini; Giuseppe Arancia; Antonio Antoccia
The tubulin-depolymerising agent combretastatin-4 induces ectopic aster assembly and mitotic catastrophe in lung cancer cells H460.
Apoptosis : an international journal on programmed cell death 2008;13(5):659-69.
2007: Stephen Hanessian; Luciana Auzzas; Giuseppe Giannini; MAURO MARZI; Walter Cabri; Marcella Barbarino; Loredana Vesci; Claudio Pisano
Omega-alkoxy analogues of SAHA (vorinostat) as inhibitors of HDAC: a study of chain-length and stereochemical dependence.
Bioorganic & medicinal chemistry letters 2007;17(22):6261-5.
2007: Claudio Pisano; Loredana Vesci; R Foderà; Fabiana Fosca Ferrara; C Rossi; Michelandrea De Cesare; Valentina Zuco; Graziella Pratesi; Rosanna Supino; Franco Zunino
Antitumor activity of the combination of synthetic retinoid ST1926 and cisplatin in ovarian carcinoma models.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(9):1500-5.
2007: Raffaella Cincinelli; Sabrina Dallavalle; Raffaella Nannei; Lucio Merlini; Sergio Penco; Giuseppe Giannini; Claudio Pisano; Loredana Vesci; Fabiana Fosca Ferrara; Valentina Zuco; Chiara Zanchi; Franco Zunino
Synthesis and structure-activity relationships of new antiproliferative and proapoptotic retinoid-related biphenyl-4-yl-acrylic acids.
Bioorganic & medicinal chemistry 2007;15(14):4863-75.
2007: Sandro Pignata; Giovanni Scambia; Claudio Pisano; Enrico Breda; Massimo Di Maio; Stefano Greggi; Gabriella Ferrandina; Domenica Lorusso; V Zagonel; Antonio Febbraro; N Riva; V De Rosa; Ciro Gallo; Francesco Perrone
A multicentre phase II study of carboplatin plus pegylated liposomal doxorubicin as first-line chemotherapy for patients with advanced or recurrent endometrial carcinoma: the END-1 study of the MITO (Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies) group.
British journal of cancer 2007;96(11):1639-43.
2007: Isabel Gomez-Monterrey; Pietro Campiglia; Alfonso Carotenuto; Daniela Califano; Claudio Pisano; Loredana Vesci; Teresa Lama; Alessia Bertamino; Marina Sala; Antonio Mazzella di Bosco; Paolo Grieco; Ettore Novellino
Design, synthesis, and cytotoxic evaluation of a new series of 3-substituted spiro[(dihydropyrazine-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)] derivatives.
Journal of medicinal chemistry 2007;50(8):1787-98.
2007: Michelandrea De Cesare; Giovanni Luca Beretta; Stella Tinelli; Valentina Benedetti; Graziella Pratesi; Sergio Penco; Sabrina Dallavalle; Lucio Merlini; Claudio Pisano; Paolo Carminati; Franco Zunino
Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series.
Biochemical pharmacology 2007;73(5):656-64.
2007: Ilio Vitale; Antonio Antoccia; Chiara Cenciarelli; Pasqualina Crateri; Stefania Meschini; Giuseppe Arancia; Claudio Pisano; Caterina Tanzarella
Combretastatin CA-4 and combretastatin derivative induce mitotic catastrophe dependent on spindle checkpoint and caspase-3 activation in non-small cell lung cancer cells.
Apoptosis : an international journal on programmed cell death 2007;12(1):155-66.
2006: edoardo parrella; Maurizio Giannì; Maddalena Fratelli; Maria Monica Barzago; Ivan Raska; Luisa Diomede; Mami Kurosaki; Claudio Pisano; Paolo Carminati; Lucio Merlini; Sabrina Dallavalle; Michele Tavecchio; Cécile Rochette-Egly; Mineko Terao; Enrico Garattini
Antitumor activity of the retinoid-related molecules (E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor gamma and retinoid-independent pathways.
Molecular pharmacology 2006;70(3):909-24.
2006: Sabrina Dallavalle; Giuseppe Giannini; Domenico Alloatti; Andrea Casati; Elena Marastoni; Loana Musso; Lucio Merlini; Gabriella Morini; Sergio Penco; Claudio Pisano; Stella Tinelli; Michelandrea De Cesare; Giovanni Luca Beretta; Franco Zunino
Synthesis and cytotoxic activity of polyamine analogues of camptothecin.
Journal of medicinal chemistry 2006;49(17):5177-86.
2006: Sandro Pignata; Claudio Pisano; Massimo Di Maio; Francesco Iodice; G Casella; Giuseppe Laurelli; Stefano Greggi; Rosario Vincenzo Iaffaioli
Medical treatment of resistant or recurrent epithelial ovarian cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17 Suppl 7():vii49-50.
2006: Daniele Simoni; LUISA-CARLOTA LÓPEZ-CARA; Riccardo Baruchello; Riccardo Rondanin; Michele Rizzi; Maria Giovanna Pavani; Domenico Alloatti; Giuseppe Giannini; Marcella Marcellini; Teresa Riccioni; Massimo Castorina; Mario B Guglielmi; Federica Bucci; Paolo Carminati; Claudio Pisano
Novel combretastatin analogues endowed with antitumor activity.
Journal of medicinal chemistry 2006;49(11):3143-52.
2006: Alma Dal Pozzo; Minghong Ni; Laura Muzi; Roberto De Castiglione; Rosanna Mondelli; Stefania Mazzini; Sergio Penco; Claudio Pisano; Massimo Castorina; Giuseppe Giannini
Incorporation of the unusual C(alpha)-fluoroalkylamino acids into cyclopeptides: synthesis of arginine-glycine-aspartate (RGD) analogues and study of their conformational and biological behavior.
Journal of medicinal chemistry 2006;49(5):1808-17.
2006: Sandro Pignata; Giovanni Scambia; Antonella Savarese; Enrico Breda; Paolo Scollo; Rocco De Vivo; Emanuela Rossi; Vittorio Gebbia; Donato Natale; Filomena Del Gaizo; Emanuele Naglieri; Antonella Ferro; Pietro Musso; Alfonso Maria D'Arco; Roberto Sorio; Claudio Pisano; Massimo Di Maio; Giuseppe Signoriello; Annalisa Annunziata; Francesco Perrone
Safety of a 3-weekly schedule of carboplatin plus pegylated liposomal doxorubicin as first line chemotherapy in patients with ovarian cancer: preliminary results of the MITO-2 randomized trial.
BMC cancer 2006;6():202.
2006: Daniela Califano; Simona Losito; Claudio Pisano; Giovanni Santelli; Stefano Greggi; Francesco Iodice; Giovanni DiVagno; Giustino Silvestro; Rosa Tambaro; Roberta Formato; Vincenzo Rosario Iaffaioli; Massimo Di Maio; Sandro Pignata
Significance of erb-B2 immunoreactivity in cervical cancer.
Frontiers in bioscience : a journal and virtual library 2006;11():2071-6.
2006: Sandro Pignata; Sabino De Placido; Rosalbino Biamonte; Giovanni Scambia; Giovanni Di Vagno; Giuseppe Colucci; Antonio Febbraro; Marco Marinaccio; Alessandra Vernaglia Lombardi; Luigi Manzione; Giacomo Cartenì; Mario Nardi; Saverio Danese; Maria Rosaria Valerio; Andrea de Matteis; Bruno Massidda; Giampietro Gasparini; Massimo Di Maio; Claudio Pisano; Francesco Perrone
Residual neurotoxicity in ovarian cancer patients in clinical remission after first-line chemotherapy with carboplatin and paclitaxel: the Multicenter Italian Trial in Ovarian cancer (MITO-4) retrospective study.
BMC cancer 2006;6():5.
2006: Massimo Di Maio; Claudio Pisano; Rosa Tambaro; Stefano Greggi; Gennaro Casella; Giuseppe Laurelli; Roberta Formato; Rosario Vincenzo Iaffaioli; Francesco Perrone; Sandro Pignata
The prognostic role of pre-chemotherapy hemoglobin level in patients with ovarian cancer.
Frontiers in bioscience : a journal and virtual library 2006;11():1585-90.
2006: Laura Belvisi; Anna Bernardi; Matteo Colombo; Leonardo Manzoni; Donatella Potenza; Carlo Scolastico; Giuseppe Giannini; Marcella Marcellini; Teresa Riccioni; Massimo Castorina; Pietro LoGiudice; Claudio Pisano
Targeting integrins: insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids.
Bioorganic & medicinal chemistry 2006;14(1):169-80.
2005: Nicola Margiotta; Paride Papadia; Francesco Lazzaro; Marcello Crucianelli; Francesco De Angelis; Claudio Pisano; Loredana Vesci; Giovanni Natile
Platinum-based antitumor drugs containing enantiomerically pure alpha-trifluoromethyl alanine as ligand.
Journal of medicinal chemistry 2005;48(24):7821-8.
2005: Giovanni Casiraghi; Gloria Rassu; Luciana Auzzas; Paola Burreddu; Enrico Gaetani; Lucia Battistini; Franca Zanardi; Claudio Curti; Giuseppe Nicastro; Laura Belvisi; Ilaria Motto; Massimo Castorina; Giuseppe Giannini; Claudio Pisano
Grafting aminocyclopentane carboxylic acids onto the RGD tripeptide sequence generates low nanomolar alphaVbeta3/alphaVbeta5 integrin dual binders.
Journal of medicinal chemistry 2005;48(24):7675-87.
2005: Laura Belvisi; Teresa Riccioni; Marcella Marcellini; Loredana Vesci; Ilaria Chiarucci; Daniela Efrati; Donatella Potenza; Carlo Scolastico; Leonardo Manzoni; Katia Lombardo; M Antonietta Stasi; Augusto Orlandi; Alessandro Ciucci; Beatrice Nico; Dragana Vukasovic; Giuseppe Giannini; Marco Presta; Paolo Carminati; Claudio Pisano
Biological and molecular properties of a new alpha(v)beta3/alpha(v)beta5 integrin antagonist.
Molecular cancer therapeutics 2005;4(11):1670-80.
2005: Claudio Pisano; Stefano Greggi; Rosa Tambaro; Simona Losito; Francesco Iodice; Massimo Di Maio; Ettore Ferrari; Marzia Falanga; Roberta Formato; Vincenzo Rosario Iaffaioli; Sandro Pignata
Activity of chemotherapy in mucinous epithelial ovarian cancer: a retrospective study.
Anticancer research 2005;25(5):3501-5.
2005: Fabio Acquaviva; Irene De Biase; Luigi Nezi; Giuseppina Ruggiero; fabiana tatangelo; Claudio Pisano; Antonella Monticelli; Corrado Garbi; Angela Maria Acquaviva; Sergio Cocozza
Extra-mitochondrial localisation of frataxin and its association with IscU1 during enterocyte-like differentiation of the human colon adenocarcinoma cell line Caco-2.
Journal of cell science 2005;118(Pt 17):3917-24.
2005: Alessandro Ottaiano; Antonella di Palma; Maria Napolitano; Claudio Pisano; Sandro Pignata; fabiana tatangelo; Gerardo Botti; Angela Maria Acquaviva; Giuseppe Castello; Paolo A Ascierto; Rosario Vincenzo Iaffaioli; Stefania Scala
Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells.
Cancer immunology, immunotherapy : CII 2005;54(8):781-91.
2005: Raffaella Cincinelli; Sabrina Dallavalle; Raffaella Nannei; Serena Carella; Daniele De Zani; Lucio Merlini; Sergio Penco; Enrico Garattini; Giuseppe Giannini; Claudio Pisano; Loredana Vesci; Paolo Carminati; Valentina Zuco; Chiara Zanchi; Franco Zunino
Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity.
Journal of medicinal chemistry 2005;48(15):4931-46.
2005: Orlando Ghirardi; Pietro Lo Giudice; Claudio Pisano; Mario Vertechy; Augusta Bellucci; Loredana Vesci; Sante Cundari; Mariarosaria Miloso; Laura Maria Rigamonti; Gabriella Nicolini; Claudio Zanna; Paolo Carminati
Acetyl-L-Carnitine prevents and reverts experimental chronic neurotoxicity induced by oxaliplatin, without altering its antitumor properties.
Anticancer research 2005;25(4):2681-7.
2005: Valentina Zuco; Chiara Zanchi; Cinzia Lanzi; Giovanni L Beretta; Rosanna Supino; Claudio Pisano; Marcella Barbarino; Romina Zanier; Federica Bucci; Concetta Aulicino; Paolo Carminati; Franco Zunino
Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response.
Neoplasia (New York, N.Y.) 2005;7(7):667-77.
2005: Margaret M Mc Gee; Sandra Gemma; Stefania Butini; Anna Ramunno; Daniela M Zisterer; Caterina Fattorusso; Bruno Catalanotti; Gagan Kukreja; Isabella Fiorini; Claudio Pisano; Carla Cucco; Ettore Novellino; Vito Nacci; D Clive Williams; Giuseppe Campiani
Pyrrolo[1,5]benzoxa(thia)zepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target.
Journal of medicinal chemistry 2005;48(13):4367-77.
2005: Claudio Pisano; Alessandro Ottaiano; fabiana tatangelo; Maurizio Di Bonito; Marzia Falanga; Vincenzo Rosario Iaffaioli; Gerardo Botti; Sandro Pignata; Angela Maria Acquaviva
Cyclooxygenase-2 expression is associated with increased size in human sporadic colorectal adenomas.
Anticancer research 2005;25(3B):2065-8.
2005: Orlando Ghirardi; Mario Vertechy; Loredana Vesci; Annalisa Canta; Gabriella Nicolini; Sara Galbiati; Cristina Ciogli; Gianni Quattrini; Claudio Pisano; Sante Cundari; Laura Maria Rigamonti
Chemotherapy-induced allodinia: neuroprotective effect of acetyl-L-carnitine.
In vivo (Athens, Greece) 2005;19(3):631-7.
2005: Annamaria Naggi; Benito Casu; Marta Perez; Giangiacomo Torri; Giuliana Cassinelli; Sergio Penco; Claudio Pisano; Giuseppe Giannini; Rivka Ishai-Michaeli; Israel Vlodavsky
Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting.
The Journal of biological chemistry 2005;280(13):12103-13.
2005: Sabrina Basciani; Marina Brama; Stefania Mariani; Gabriele De Luca; Mario Arizzi; Loredana Vesci; Claudio Pisano; Susanna Dolci; Giovanni Spera; Lucio Gnessi
Imatinib mesylate inhibits Leydig cell tumor growth: evidence for in vitro and in vivo activity.
Cancer research 2005;65(5):1897-903.
2005: Isabel Gomez-Monterrey; Giovanni Santelli; Pietro Campiglia; Daniela Califano; Fabiano Falasconi; Claudio Pisano; Loredana Vesci; Teresa Lama; Paolo Grieco; Ettore Novellino
Synthesis and cytotoxic evaluation of novel spirohydantoin derivatives of the dihydrothieno[2,3-b]naphtho-4,9-dione system.
Journal of medicinal chemistry 2005;48(4):1152-7.
2005: Claudio Pisano; Concetta Aulicino; Loredana Vesci; Benito Casu; Annamaria Naggi; Giangiacomo Torri; Dragana Vukasovic; Mirella Belleri; MARCO RUSNATI; Marco Presta
Undersulfated, low-molecular-weight glycol-split heparin as an antiangiogenic VEGF antagonist.
Glycobiology 2005;15(2):1C-6C.
2005: Alessandro Ottaiano; Ernesto Mollo; Giuseppe Di Lorenzo; Claudio Pisano; Massimo Di Maio; Emiddio Barletta; Matilde Pensabene; Romana Segati; Pierluigi Bullian; Guglielmo Nasti; Jane Bryce; Stefania Scala; Giuseppe Castello; Paolo A Ascierto
Prospective clinical trials of biotherapies in solid tumors: a 5-year survey.
Cancer immunology, immunotherapy : CII 2005;54(1):44-50.
2004: Claudio Pisano; Lucio Merlini; Sergio Penco; Paolo Carminati; Franco Zunino
Cellular and pharmacological bases of the antitumor activity of a novel adamantyl retinoid, ST1926.
Journal of chemotherapy (Florence, Italy) 2004;16 Suppl 4():74-6.
2004: Michela Errico; Teresa Riccioni; Shalini Iyer; Claudio Pisano; K Ravi Acharya; M Graziella Persico; Sandro De Falco
Identification of placenta growth factor determinants for binding and activation of Flt-1 receptor.
The Journal of biological chemistry 2004;279(42):43929-39.
2004: Rosa Tambaro; Giovanni Scambia; Massimo Di Maio; Claudio Pisano; Emiddio Barletta; Vincenzo Rosario Iaffaioli; Sandro Pignata
The role of chemotherapy in locally advanced, metastatic and recurrent cervical cancer.
Critical reviews in oncology/hematology 2004;52(1):33-44.
2004: Claudio Pisano; Rosa Tambaro; Massimo Di Maio; Roberta Formato; Vincenzo Rosario Iaffaioli; Sandro Pignata
Complete resolution of psoriasis in a patient treated with stealth liposomal doxorubicin and carboplatin for ovarian cancer.
Archives of dermatological research 2004;296(3):141-2.
2004: Alessandro Ottaiano; Anna De Chiara; Francesco Perrone; Gerardo Botti; Flavio Fazioli; Vincenzo De Rosa; Nicola Mozzillo; Vincenzo Ravo; Brunello Morrica; Ciro Gallo; Claudio Pisano; Maria Napolitano; Paolo A Ascierto; Rosario Vincenzo Iaffaioli; Gaetano Apice
Prognostic value of CD40 in adult soft tissue sarcomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2824-31.
2004: Valentina Zuco; Chiara Zanchi; Giuliana Cassinelli; Cinzia Lanzi; Rosanna Supino; Claudio Pisano; Romina Zanier; Vincenzo Giordano; Enrico Garattini; Franco Zunino
Induction of apoptosis and stress response in ovarian carcinoma cell lines treated with ST1926, an atypical retinoid.
Cell death and differentiation 2004;11(3):280-9.
2004: Benito Casu; marco Guerrini; Sara Guglieri; Annamaria Naggi; Marta Perez; Giangiacomo Torri; Giuliana Cassinelli; Dragana Vukasovic; Paolo Carminati; Giuseppe Giannini; Sergio Penco; Claudio Pisano; Mirella Belleri; MARCO RUSNATI; Marco Presta
Undersulfated and glycol-split heparins endowed with antiangiogenic activity.
Journal of medicinal chemistry 2004;47(4):838-48.
2004: Pasquale Stano; Simone Bufali; Claudio Pisano; Federica Bucci; Marcella Barbarino; Mosè Santaniello; Paolo Carminati; Pier Luigi Luisi
Novel camptothecin analogue (gimatecan)-containing liposomes prepared by the ethanol injection method.
Journal of liposome research 2004;14(1-2):87-109.
2004: Enrico Garattini; edoardo parrella; Luisa Diomede; Maurizio Gianni'; Yesim Kalac; Lucio Merlini; Daniele Simoni; Romina Zanier; Fabiana Fosca Ferrara; Ilaria Chiarucci; Paolo Carminati; Mineko Terao; Claudio Pisano
ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis.
Blood 2004;103(1):194-207.
2003: Claudio Pisano; Graziella Pratesi; Diletta Laccabue; Franco Zunino; Pietro Lo Giudice; Augusta Bellucci; Licia Pacifici; Barbara Camerini; Loredana Vesci; Massimo Castorina; Sandra Cicuzza; Giovanni Tredici; Paola Marmiroli; Gabriella Nicolini; Sara Galbiati; Menotti Calvani; Paolo Carminati; Guido Cavaletti
Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5756-67.
2003: Giovanna Petrangolini; Graziella Pratesi; Michelandrea De Cesare; Rosanna Supino; Claudio Pisano; Marcella Marcellini; Vincenzo Giordano; Diletta Laccabue; Cinzia Lanzi; Franco Zunino
Antiangiogenic effects of the novel camptothecin ST1481 (gimatecan) in human tumor xenografts.
Molecular cancer research : MCR 2003;1(12):863-70.
2003: Rosa Tambaro; Stefano Greggi; Rosario Vincenzo Iaffaioli; Antonio Rossi; Claudio Pisano; Luigi Manzione; Ettore Ferrari; Massimo Di Maio; Francesco Iodice; G Casella; Giuseppe Laurelli; Sandro Pignata
An escalating dose finding study of liposomal doxorubicin and vinorelbine for the treatment of refractory or resistant epithelial ovarian cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(9):1406-11.
2003: G Giannini; S Penco; Claudio Pisano; Teresa Riccioni; Gianluca Nasini; G Candiani
Chrysanthones, a new source of fungal metabolites with potential antitumor and antiangiogenesis properties.
Fitoterapia 2003;74(4):323-7.
2003: Valentina Zuco; Rosanna Supino; Michelandrea De Cesare; Nives Carenini; Paola Perego; Laura Gatti; Graziella Pratesi; Claudio Pisano; Roberta Martinelli; Federica Bucci; Romina Zanier; Paolo Carminati; Franco Zunino
Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models.
Biochemical pharmacology 2003;65(8):1281-94.
2003: Raffaella Cincinelli; Sabrina Dallavalle; Lucio Merlini; Sergio Penco; Claudio Pisano; Paolo Carminati; Giuseppe Giannini; Loredana Vesci; carlo gaetano; Barbara Illy; Valentina Zuco; Rosanna Supino; Franco Zunino
A novel atypical retinoid endowed with proapoptotic and antitumor activity.
Journal of medicinal chemistry 2003;46(6):909-12.
2003: Alessandro Ottaiano; Claudio Pisano; Anna De Chiara; Emiddio Barletta; A P Ascierto; Gerardo Botti; M Napolitano; Gaetano Apice; Rosario Vincenzo Iaffaioli
Expression of CD40 has no predictive value in soft tissue sarcomas.
Anticancer research 2003;23(2B):1597-604.
2003: Israel Vlodavsky; Eyal Zcharia; Orit Goldshmidt; Rinat Eshel; Ben-Zion Katz; Saverio Minucci; O Kovalchuk; Sergio Penco; Claudio Pisano; Annamaria Naggi; Benito Casu
Involvement of heparanase in tumor progression and normal differentiation.
Pathophysiology of haemostasis and thrombosis 2003;33 Suppl 1():59-61.
2002: Graziella Pratesi; Michelandrea De Cesare; Nives Carenini; Paola Perego; Sabina C Righetti; Carla Cucco; Lucio Merlini; Claudio Pisano; Sergio Penco; Paolo Carminati; Loredana Vesci; Franco Zunino
Pattern of antitumor activity of a novel camptothecin, ST1481, in a large panel of human tumor xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3904-9.
2002: Claudio Pisano; Peter Kollar; Maurizio Gianní; Yesim Kalac; Vincenzo Giordano; Fabiana Fosca Ferrara; Richard Tancredi; Antonio Devoto; Alessandra Rinaldi; Alessandro Rambaldi; Sergio Penco; MAURO MARZI; Giampiero Moretti; Loredana Vesci; Ornella Tinti; Paolo Carminati; Mineko Terao; Enrico Garattini
Bis-indols: a novel class of molecules enhancing the cytodifferentiating properties of retinoids in myeloid leukemia cells.
Blood 2002;100(10):3719-30.
2002: Alessandro Ottaiano; Emiddio Barletta; Paolo Maione; Francesco Fiore; Claudio Pisano; Massimo Di Maio; Vincenzo Rosario Iaffaioli; Cesare Gridelli
Pancreatic involvement from heavily pretreated small cell lung cancer successfully treated with transcatheter intra-arterial chemotherapy: a case report with local and systemic disease control.
Tumori 2002;88(6):535-7.
2002: Alessandro Ottaiano; Claudio Pisano; Anna De Chiara; Paolo A Ascierto; Gerardo Botti; Emiddio Barletta; Gaetano Apice; Cesare Gridelli; Vincenzo Rosario Iaffaioli
CD40 activation as potential tool in malignant neoplasms.
Tumori 2002;88(5):361-6.
2002: Benito Casu; marco Guerrini; Annamaria Naggi; Marta Perez; Giangiacomo Torri; Dragana Vukasovic; Paolo Carminati; Giuseppe Giannini; Sergio Penco; Claudio Pisano; Mirella Belleri; MARCO RUSNATI; Marco Presta
Short heparin sequences spaced by glycol-split uronate residues are antagonists of fibroblast growth factor 2 and angiogenesis inhibitors.
Biochemistry 2002;41(33):10519-28.
2002: Gabriella Coruzzi; Gabriella Coppelli; Silvana Spaggiari; Giulia Martina Cavestro; Lajos Okolicsanyi; Pietro Lo Giudice; Claudio Pisano; B L Tepperman
Gastroprotective effects of amtolmetin guacyl: a new non-steroidal anti-inflammatory drug that activates inducible gastric nitric oxide synthase.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2002;34(6):403-10.
2002: Sandro Pignata; Massimo Di Maio; Alessandro Ottaiano; Ermelinda De Maio; Emiddio Barletta; Claudio Pisano; Rosa Tambaro
Single agents or combination chemotherapy for advanced ovarian carcinoma in elderly patients: pro single agents.
Tumori 2002;88(1 Suppl 1):S117-9.
2001: Michelandrea De Cesare; Graziella Pratesi; Paola Perego; Nives Carenini; Stella Tinelli; Lucio Merlini; Sergio Penco; Claudio Pisano; Federica Bucci; Loredana Vesci; S Pace; F Capocasa; Paolo Carminati; Franco Zunino
Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin.
Cancer research 2001;61(19):7189-95.
2001: Sabrina Dallavalle; A Ferrari; Barbara Biasotti; Lucio Merlini; Sergio Penco; Grazia Gallo; MAURO MARZI; Maria Ornella Tinti; Roberta Martinelli; Claudio Pisano; Paolo Carminati; Nives Carenini; Giovanni Luca Beretta; Paola Perego; Michelandrea De Cesare; Graziella Pratesi; Franco Zunino
Novel 7-oxyiminomethyl derivatives of camptothecin with potent in vitro and in vivo antitumor activity.
Journal of medicinal chemistry 2001;44(20):3264-74.
2001: Paola Perego; Michelandrea De Cesare; P De Isabella; Nives Carenini; Gino Beggiolin; Gabriella Pezzoni; Manlio Palumbo; L Tartaglia; Graziella Pratesi; Claudio Pisano; Paolo Carminati; G L Scheffer; Franco Zunino
A novel 7-modified camptothecin analog overcomes breast cancer resistance protein-associated resistance in a mitoxantrone-selected colon carcinoma cell line.
Cancer research 2001;61(16):6034-7.
2001: Laura Belvisi; Anna Bernardi; A Checchia; Leonardo Manzoni; Donatella Potenza; Carlo Scolastico; Massimo Castorina; A Cupelli; Giuseppe Giannini; Paolo Carminati; Claudio Pisano
Potent integrin antagonists from a small library of RGD-including cyclic pseudopeptides.
Organic letters 2001;3(7):1001-4.
2000: Claudio Pisano; A Battistoni; Antonio Antoccia; Francesca Degrassi; Caterina Tanzarella
Changes in microtubule organization after exposure to a benzimidazole derivative in Chinese hamster cells.
Mutagenesis 2000;15(6):507-15.
2000: Michelandrea De Cesare; Franco Zunino; S Pace; Claudio Pisano; Graziella Pratesi
Efficacy and toxicity profile of oral topotecan in a panel of human tumour xenografts.
European journal of cancer (Oxford, England : 1990) 2000;36(12):1558-64.
1999: Claudio Pisano; Daniela Grandi; Giovanni Morini; Gabriella Coppelli; Loredana Vesci; Pietro Lo Giudice; S Pace; Licia Pacifici; Antonio Longo; Gabriella Coruzzi; Paolo Carminati
Gastrosparing effect of new antiinflammatory drug amtolmetin guacyl in the rat: involvement of nitric oxide.
Digestive diseases and sciences 1999;44(4):713-24.
1997: A Battistoni; Giulia Guarguaglini; Francesca Degrassi; Carmine Pittoggi; Antonella Palena; G Di Matteo; Claudio Pisano; Enrico Cundari; Patrizia Lavia
Deregulated expression of the RanBP1 gene alters cell cycle progression in murine fibroblasts.
Journal of cell science 1997;110 ( Pt 19)():2345-57.

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