FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Donald Bers

Research Profile

Chemicals & Drugs

Anatomy

Disorders

Living Beings

Physiology

Calcium Signaling

Phenomena

Phosphorylation

Co-author Network

Publications

TOP 3
Stefan Neef; Laetitia Pereira; Can M Sag; Johannes Backs; Henrik Bäumer; Donald M Bers; Maria Daut; Jaime DeSantiago; Ali El-Armouche; Clemens Grefe; Lars S Maier
While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO mice.
Chang Sik Park; Inju Park; Woo Jin Park; Vivek P Singh; Hong-Sheng Wang; Evangelia G Kranias; Hoyong Lee; Jae Gyun Oh; Donald M Bers; Hyeseon Cha; Shan Chen; Chunghee Cho; Clara Franzini-Armstrong; Kenneth S Ginsburg; Peidong Han; Sunghee Hong; Sora Jin; Do Han Kim
Targeted ablation of the histidine-rich Ca(2+)-binding protein (HRC) gene is associated with abnormal SR Ca(2+)-cycling and severe pathology under pressure-overload stress.
W Jonathan Lederer; Donald M Bers; David A Eisner
Calcium signaling in heart: Multiscale, diverse, rapid, local, and remarkable.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Donald Bers (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Stefan Neef; Laetitia Pereira; Can M Sag; Johannes Backs; Henrik Bäumer; Donald M Bers; Maria Daut; Jaime DeSantiago; Ali El-Armouche; Clemens Grefe; Lars S Maier
While systolic cardiomyocyte function is preserved, diastolic myocyte function and recovery from acidosis are impaired in CaMKIIδ-KO mice.
Journal of molecular and cellular cardiology 2013;59():107-16.
2013: Chang Sik Park; Inju Park; Woo Jin Park; Vivek P Singh; Hong-Sheng Wang; Evangelia G Kranias; Hoyong Lee; Jae Gyun Oh; Donald M Bers; Hyeseon Cha; Shan Chen; Chunghee Cho; Clara Franzini-Armstrong; Kenneth S Ginsburg; Peidong Han; Sunghee Hong; Sora Jin; Do Han Kim
Targeted ablation of the histidine-rich Ca(2+)-binding protein (HRC) gene is associated with abnormal SR Ca(2+)-cycling and severe pathology under pressure-overload stress.
Basic research in cardiology 2013;108(3):344.
2013: W Jonathan Lederer; Donald M Bers; David A Eisner
Calcium signaling in heart: Multiscale, diverse, rapid, local, and remarkable.
Journal of molecular and cellular cardiology 2013;58():3-4.
2013: Yuanfang Xie; Eleonora Grandi; Jose L Puglisi; Daisuke Sato; Donald M Bers
β-adrenergic stimulation activates early afterdepolarizations transiently via kinetic mismatch of PKA targets.
Journal of molecular and cellular cardiology 2013;58():153-61.
2013: Donald M Bers; Thomas R Shannon
Calcium movements inside the sarcoplasmic reticulum of cardiac myocytes.
Journal of molecular and cellular cardiology 2013;58():59-66.
2013: Ping Liang; Patricia K Nguyen; Robert C Robbins; Karim Sallam; Veronica Sanchez-Freire; Paul J Wang; Yongming Wang; Donald M Bers; Sebastian Diecke; Tingyu Gong; Joshua W Knowles; Feng Lan; Andrew S Lee; Joseph C Wu
Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
Circulation 2013;127(16):1677-91.
2013: Kenneth S Ginsburg; Christopher R Weber; Donald M Bers
Cardiac Na+-Ca2+ exchanger: dynamics of Ca2+-dependent activation and deactivation in intact myocytes.
The Journal of physiology 2013;591(Pt 8):2067-86.
2013: Roger C Thomas; Donald M Bers
How to make calcium-sensitive microelectrodes.
Cold Spring Harbor protocols 2013;2013(4):374-8.
2013: Roger C Thomas; Donald M Bers
How to make calcium-sensitive minielectrodes.
Cold Spring Harbor protocols 2013;2013(4):370-3.
2013: Roger C Thomas; Donald M Bers
Calcium-sensitive mini- and microelectrodes.
Cold Spring Harbor protocols 2013;2013(4):305-9.
2013: Jose L Puglisi; Ye Chen-Izu; Jorge A Negroni; Donald M Bers
The force-frequency relationship: insights from mathematical modeling.
Advances in physiology education 2013;37(1):28-34.
2013: Laëtitia Pereira; Ralph J van Oort; Xander H T Wehrens; Joan Heller Brown; Ju Chen; Hongqiang Cheng; Dieu-Hung Lao; Li Na; Donald M Bers
Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2+ leak and arrhythmia.
Circulation 2013;127(8):913-22.
2013: Xiyuan Lu; Godfrey L Smith; Julie Bossuyt; Kenneth S Ginsburg; Sarah Kettlewell; Donald M Bers
Measuring local gradients of intramitochondrial [Ca(2+)] in cardiac myocytes during sarcoplasmic reticulum Ca(2+) release.
Circulation research 2013;112(3):424-31.
2013: Tetsuro Oda; Bengt Svensson; Yi Yang; Razvan L Cornea; Bradley R Fruen; Xiyuan Lu; Florentin R Nitu; Donald M Bers
In cardiomyocytes, binding of unzipping peptide activates ryanodine receptor 2 and reciprocally inhibits calmodulin binding.
Circulation research 2013;112(3):487-97.
2013: Donald M Bers
Membrane receptor neighborhoods: snuggling up to the nucleus.
Circulation research 2013;112(2):224-6.
2013: Chia-Wei Jenny Chang; Khanha Dao; Linda Lee; David Yu; Julie Bossuyt; Donald M Bers
Acute β-adrenergic activation triggers nuclear import of histone deacetylase 5 and delays G(q)-induced transcriptional activation.
The Journal of biological chemistry 2013;288(1):192-204.
2013: Feng Lan; Andrew S Lee; Richard Lewis; Ping Liang; Michael T Longaker; Enrique G Navarrete; Patricia K Nguyen; Beth Pruitt; Robert C Robbins; Veronica Sanchez-Freire; Chelsey S Simmons; Ning Sun; Li Wang; Yongming Wang; Matthew Wheeler; Oscar Abilez; Euan A Ashley; Donald M Bers; Antje D Ebert; Leng Han; Shijun Hu; Yoshinori Yamaguchi; Michelle Yen; Joseph C Wu
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells.
Cell stem cell 2013;12(1):101-13.
2013: Jessica I Gold; Jonathan Hullmann; Donald M Bers; Julie Bossuyt; J Kurt Chuprun; Erhe Gao; Linda Lee; Jeffrey S Martini; Joseph E Rabinowitz; Douglas G Tilley; Walter J Koch
Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process.
PloS one 2013;8(3):e57324.
2012: Mounir Khafaga; Linda L Lee; Joseph C Li; Luiza Mamikonian; Vladimir Yarov-Yarovoy; Julie Bossuyt; Sanda Despa; Donald M Bers
Na⁺/K⁺-ATPase E960 and phospholemman F28 are critical for their functional interaction.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(50):20756-61.
2012: Benjamin E Jin; Jonathan H Widdicombe; Heike Wulff; Jie Zheng; Donald M Bers; Jose L Puglisi
A simple device to illustrate the Einthoven triangle.
Advances in physiology education 2012;36(4):319-24.
2012: Donald M Bers; Anthony W Herren
Na(+) channel I-II loop mediates parallel genetic and phosphorylation-dependent gating changes.
Circulation 2012;126(17):2042-6.
2012: Le Chen; Nipavan Chiamvimonvat; Gino Cortopassi; Vanessa J Davies; Tingting Liu; Xiyuan Lu; Alexey A Tomilov; Alice Tran; Marcela Votruba; Donald M Bers; Anne Knowlton
OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability.
Journal of the American Heart Association 2012;1(5):e003012.
2012: Stefano Morotti; Aurora Summa; Kenneth S Ginsburg; Eleonora Grandi; Donald M Bers
Theoretical study of L-type Ca(2+) current inactivation kinetics during action potential repolarization and early afterdepolarizations.
The Journal of physiology 2012;590(Pt 18):4465-81.
2012: Sanda Despa; Jerry B Lingrel; Donald M Bers
Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes.
Cardiovascular research 2012;95(4):480-6.
2012: Nicole M Ashpole; Donald M Bers; Joseph D Brogan; Theodore R Cummins; Kenneth S Ginsburg; Anthony W Herren; Derrick E Johnson; Andy Hudmon
Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites.
The Journal of biological chemistry 2012;287(24):19856-69.
2012: Tao Guo; Shikha Mishra; Tong Zhang; Joan Heller Brown; Kenneth S Ginsburg; Donald M Bers
CaMKIIδC slows [Ca]i decline in cardiac myocytes by promoting Ca sparks.
Biophysical journal 2012;102(11):2461-70.
2012: Emmanuel Camors; Donald M Bers; Peter J Mohler; Sanda Despa
Ankyrin-B reduction enhances Ca spark-mediated SR Ca release promoting cardiac myocyte arrhythmic activity.
Journal of molecular and cellular cardiology 2012;52(6):1240-8.
2012: Rachel C Myles; Donald M Bers; Chaoyi Kang; Lianguo Wang; Crystal M Ripplinger
Local β-adrenergic stimulation overcomes source-sink mismatch to generate focal arrhythmia.
Circulation research 2012;110(11):1454-64.
2012: Daisuke Sato; Sanda Despa; Donald M Bers
Can the sodium-calcium exchanger initiate or suppress calcium sparks in cardiac myocytes?
Biophysical journal 2012;102(8):L31-3.
2012: Donald M Bers
Ryanodine receptor S2808 phosphorylation in heart failure: smoking gun or red herring.
Circulation research 2012;110(6):796-9.
2012: Kobra Haghighi; Ahmad Anjak; Donald M Bers; Julie Bossuyt; Guo-Chang Fan; Hanna Osinska; Tracy Pritchard; Jeffrey Robbins; Jack Rubinstein; Jason R Waggoner; Qunying Yuan; Evangelia G Kranias
The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPase.
Journal of molecular and cellular cardiology 2012;52(3):773-82.
2012: Crystal M Ripplinger; Donald M Bers
Human biological pacemakers: intrinsic variability and stability.
Circulation 2012;125(7):856-8.
2012: Sanda Despa; Peter J Havel; Anne Knowlton; Kenneth B Margulies; Heinrich Taegtmeyer; Donald M Bers; Le Chen; Florin Despa
Hyperamylinemia contributes to cardiac dysfunction in obesity and diabetes: a study in humans and rats.
Circulation research 2012;110(4):598-608.
2012: Jeffrey J Saucerman; Donald M Bers
Calmodulin binding proteins provide domains of local Ca2+ signaling in cardiac myocytes.
Journal of molecular and cellular cardiology 2012;52(2):312-6.
2012: Sanjeewa A Goonasekera; Steven Reiken; Hongyu Zhang; Mannix Auger-Messier; Karin Hammer; John W Elrod; Michelle A Sargent; Andrew R Marks; Xiongwen Chen; Donald M Bers; Sven Moosmang; Steven R Houser; Robert N Correll; Franz Hofmann; Ilona Bodi; Allen J York; Jeffery D Molkentin
Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice.
The Journal of clinical investigation 2012;122(1):280-90.
2012: Laetitia Pereira; Frank Lezoualc'h; Eric Morel; Jean-Pierre Benitah; Alejandro Domínguez-Rodríguez; Gema Ruiz-Hurtado; Alexandre Lucas; Donald M Bers; Sandra Lauton-Santos; Mélanie Métrich; Anne-Coline Laurent; Ana M Gómez
Epac enhances excitation-transcription coupling in cardiac myocytes.
Journal of molecular and cellular cardiology 2012;52(1):283-91.
2011: Shikha Mishra; Donald M Bers; Shigeki Miyamoto; Charles B B Gray; Joan Heller Brown
Location matters: clarifying the concept of nuclear and cytosolic CaMKII subtypes.
Circulation research 2011;109(12):1354-62.
2011: Daisuke Sato; Donald M Bers
How does stochastic ryanodine receptor-mediated Ca leak fail to initiate a Ca spark?
Biophysical journal 2011;101(10):2370-9.
2011: Tao Guo; Trinh D Nguyen; Florentin R Nitu; Yi Yang; Razvan L Cornea; Bradley R Fruen; Donald M Bers
FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel.
Biophysical journal 2011;101(9):2170-7.
2011: Eleonora Grandi; Jose Jalife; Sandeep Vinayak Pandit; Niels Voigt; Antony J Workman; Dobromir Dobrev; Donald M Bers
Human atrial action potential and Ca2+ model: sinus rhythm and chronic atrial fibrillation.
Circulation research 2011;109(9):1055-66.
2011: Mark E Anderson; Joan Heller Brown; Donald M Bers
CaMKII in myocardial hypertrophy and heart failure.
Journal of molecular and cellular cardiology 2011;51(4):468-73.
2011: Julie Bossuyt; Sven Bossuyt; Kenneth S Campbell; Chia-Wei Chang; Kathryn Helmstadter; Maya T Kunkel; Jody L Martin; Alexandra C Newton; Seth L Robia; Donald M Bers
Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelin.
The Journal of biological chemistry 2011;286(38):33390-400.
2011: Jeffrey R Erickson; Amanda Ferguson; Ruchi Patel; Julie Bossuyt; Donald M Bers
Fluorescence resonance energy transfer-based sensor Camui provides new insight into mechanisms of calcium/calmodulin-dependent protein kinase II activation in intact cardiomyocytes.
Circulation research 2011;109(7):729-38.
2011: Sakthivel Sadayappan; Metin Avkiran; David Barefield; Donald M Bers; Joan Heller Brown; Friederike Cuello; James Gulick; Jeanne James; Valerie M Lasko; John N Lorenz; Marjorie Maillet; Jody L Martin; Jeffery D Molkentin; Hanna Osinska; Jeffrey Robbins
A critical function for Ser-282 in cardiac Myosin binding protein-C phosphorylation and cardiac function.
Circulation research 2011;109(2):141-50.
2011: Donald M Bers; Eleonora Grandi
Human atrial fibrillation: insights from computational electrophysiological models.
Trends in cardiovascular medicine 2011;21(5):145-50.
2011: Donald M Bers
Ca²⁺-calmodulin-dependent protein kinase II regulation of cardiac excitation-transcription coupling.
Heart rhythm : the official journal of the Heart Rhythm Society 2011;8(7):1101-4.
2011: Donald M Bers; Samantha Harris
Translational medicine: to the rescue of the failing heart.
Nature 2011;473(7345):36-9.
2011: Donald M Bers
Calmodulin and S100A1 fine tune skeletal muscle E-C coupling. Focus on "Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1".
American journal of physiology. Cell physiology 2011;300(5):C974-5.
2011: Lin Wu; Jihua Ma; Hong Li; Chao Wang; Eleonora Grandi; Peihua Zhang; Antao Luo; Donald M Bers; John C Shryock; Luiz Belardinelli
Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.
Circulation 2011;123(16):1713-20.
2011: Eckard Picht; Aleksey V Zima; Thomas R Shannon; Alexis M Duncan; Lothar A Blatter; Donald M Bers
Dynamic calcium movement inside cardiac sarcoplasmic reticulum during release.
Circulation research 2011;108(7):847-56.
2011: Qiujing Song; Sandeep Pallikkuth; Julie Bossuyt; Donald M Bers; Seth L Robia
Phosphomimetic mutations enhance oligomerization of phospholemman and modulate its interaction with the Na/K-ATPase.
The Journal of biological chemistry 2011;286(11):9120-6.
2011: Stefan Wagner; Hanna M Ruff; Sarah L Weber; Sarah Bellmann; Thomas Sowa; Timo Schulte; Mark E Anderson; Eleonora Grandi; Donald M Bers; Johannes Backs; Luiz Belardinelli; Lars S Maier
Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload.
Circulation research 2011;108(5):555-65.
2011: José L Puglisi; Weilong Yuan; Valeriy Timofeyev; Richard E Myers; Nipavan Chiamvimonvat; Allen M Samarel; Donald M Bers
Phorbol ester and endothelin-1 alter functional expression of Na+/Ca2+ exchange, K+, and Ca2+ currents in cultured neonatal rat myocytes.
American journal of physiology. Heart and circulatory physiology 2011;300(2):H617-26.
2011: Sabine Huke; Jaime DeSantiago; Marcia A Kaetzel; Shikha Mishra; Joan H Brown; John R Dedman; Donald M Bers
SR-targeted CaMKII inhibition improves SR Ca²+ handling, but accelerates cardiac remodeling in mice overexpressing CaMKIIδC.
Journal of molecular and cellular cardiology 2011;50(1):230-8.
2010: Ralph J van Oort; Mark D McCauley; Sayali S Dixit; Laetitia Pereira; Yi Yang; Jonathan L Respress; Qiongling Wang; Angela C De Almeida; Darlene G Skapura; Mark E Anderson; Donald M Bers; Xander H T Wehrens
Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure.
Circulation 2010;122(25):2669-79.
2010: Hui Xu; Kenneth S Ginsburg; Duane D Hall; Maike Zimmermann; Ivar S Stein; Mingxu Zhang; Samvit Tandan; Joseph A Hill; Mary C Horne; Donald M Bers; Johannes Hell
Targeting of protein phosphatases PP2A and PP2B to the C-terminus of the L-type calcium channel Ca v1.2.
Biochemistry 2010;49(48):10298-307.
2010: Aleksey V Zima; Elisa Bovo; Donald M Bers; Lothar A Blatter
Ca²+ spark-dependent and -independent sarcoplasmic reticulum Ca²+ leak in normal and failing rabbit ventricular myocytes.
The Journal of physiology 2010;588(Pt 23):4743-57.
2010: Fei Han; Julie Bossuyt; Jody L Martin; Sanda Despa; Donald M Bers
Role of phospholemman phosphorylation sites in mediating kinase-dependent regulation of the Na+-K+-ATPase.
American journal of physiology. Cell physiology 2010;299(6):C1363-9.
2010: Shikha Mishra; Haiyun Ling; Michael Grimm; Tong Zhang; Donald M Bers; Joan Heller Brown
Cardiac hypertrophy and heart failure development through Gq and CaM kinase II signaling.
Journal of cardiovascular pharmacology 2010;56(6):598-603.
2010: Donald M Bers
Digitalis and Na/Ca exchange: old dog learns new mitochondrial tricks.
Journal of molecular and cellular cardiology 2010;49(5):713-4.
2010: Donald M Bers
CaMKII inhibition in heart failure makes jump to human.
Circulation research 2010;107(9):1044-6.
2010: Hiroyuki Nakayama; Ilona Bodi; Marjorie Maillet; Jaime DeSantiago; Timothy L Domeier; Katsuhiko Mikoshiba; John N Lorenz; Lothar A Blatter; Donald M Bers; Jeffery D Molkentin
The IP3 receptor regulates cardiac hypertrophy in response to select stimuli.
Circulation research 2010;107(5):659-66.
2010: Eleonora Grandi; Stefano Morotti; Kenneth S Ginsburg; Stefano Severi; Donald M Bers
Interplay of voltage and Ca-dependent inactivation of L-type Ca current.
Progress in biophysics and molecular biology 2010;103(1):44-50.
2010: Jerry Curran; Kathy Hayes Brown; Demetrio J Santiago; Steven M Pogwizd; Donald M Bers; Thomas R Shannon
Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II.
Journal of molecular and cellular cardiology 2010;49(1):25-32.
2010: Tao Guo; Razvan L Cornea; Sabine Huke; Emmanuel Camors; Yi Yang; Eckard Picht; Bradley R Fruen; Donald M Bers
Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks.
Circulation research 2010;106(11):1743-52.
2010: Andreas Rinne; Nidhi Kapur; Jeffery D Molkentin; Steven M Pogwizd; Donald M Bers; Kathrin Banach; Lothar A Blatter
Isoform- and tissue-specific regulation of the Ca(2+)-sensitive transcription factor NFAT in cardiac myocytes and heart failure.
American journal of physiology. Heart and circulatory physiology 2010;298(6):H2001-9.
2010: Demetrio J Santiago; Jerald W Curran; Donald M Bers; W Jonathan Lederer; Michael D Stern; Eduardo Ríos; Thomas R Shannon
Ca sparks do not explain all ryanodine receptor-mediated SR Ca leak in mouse ventricular myocytes.
Biophysical journal 2010;98(10):2111-20.
2010: Donald M Bers
Calcium channels are ganging up in the sarcolemma.
Circulation research 2010;106(4):625-6.
2010: Donald M Bers; Kenneth S Ginsburg
Minding the store of Ca2+ during ischaemia/reperfusion.
Cardiovascular research 2010;85(4):641-2.
2010: Tong Zhang; Tao Guo; Shikha Mishra; Nancy Dalton; Evangelia G Kranias; Kirk L Peterson; Donald M Bers; Joan Heller Brown
Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice.
Circulation research 2010;106(2):354-62.
2010: Leif Hove-Madsen; S Baudet; Donald M Bers
Making and using calcium-selective mini- and microelectrodes.
Methods in cell biology 2010;99():67-89.
2010: Donald M Bers; Chris W Patton; Richard Nuccitelli
A practical guide to the preparation of Ca(2+) buffers.
Methods in cell biology 2010;99():1-26.
2010: Eleonora Grandi; Francesco S Pasqualini; Donald M Bers
A novel computational model of the human ventricular action potential and Ca transient.
Journal of molecular and cellular cardiology 2010;48(1):112-21.
2009: Paul J Schaeffer; Jaime DeSantiago; John Yang; Thomas P Flagg; Attila Kovacs; Carla Weinheimer; Michael Courtois; Teresa C Leone; Colin G Nichols; Donald M Bers; Daniel P Kelly
Impaired contractile function and calcium handling in hearts of cardiac-specific calcineurin b1-deficient mice.
American journal of physiology. Heart and circulatory physiology 2009;297(4):H1263-73.
2009: Julie Bossuyt; Sanda Despa; Fei Han; Zhanjia Hou; Seth L Robia; Jerry B Lingrel; Donald M Bers
Isoform specificity of the Na/K-ATPase association and regulation by phospholemman.
The Journal of biological chemistry 2009;284(39):26749-57.
2009: Fei Han; Amy L Tucker; Jerry B Lingrel; Sanda Despa; Donald M Bers
Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman.
American journal of physiology. Cell physiology 2009;297(3):C699-705.
2009: Donald M Bers; Eleonora Grandi
Calcium/calmodulin-dependent kinase II regulation of cardiac ion channels.
Journal of cardiovascular pharmacology 2009;54(3):180-7.
2009: Stefan Wagner; Elena Hacker; Eleonora Grandi; Sarah L Weber; Nataliya Dybkova; Samuel Sossalla; Thomas Sowa; Larissa Fabritz; Paulus Kirchhof; Donald M Bers; Lars S Maier
Ca/calmodulin kinase II differentially modulates potassium currents.
Circulation. Arrhythmia and electrophysiology 2009;2(3):285-94.
2009: Tatyana N Andrienko; Eckard Picht; Donald M Bers
Mitochondrial free calcium regulation during sarcoplasmic reticulum calcium release in rat cardiac myocytes.
Journal of molecular and cellular cardiology 2009;46(6):1027-36.
2009: Elizabeth Murphy; Donald M Bers; Rosario Rizzuto
Mitochondria: from basic biology to cardiovascular disease.
Journal of molecular and cellular cardiology 2009;46(6):765-6.
2009: Donald M Bers; Sanda Despa
Na/K-ATPase--an integral player in the adrenergic fight-or-flight response.
Trends in cardiovascular medicine 2009;19(4):111-8.
2009: Haiyun Ling; Tong Zhang; Laetitia Pereira; Christopher Kable Means; Hongqiang Cheng; Yusu Gu; Nancy D Dalton; Kirk L Peterson; Ju Chen; Donald M Bers; Joan Heller Brown; Joan Heller Brown
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice.
The Journal of clinical investigation 2009;119(5):1230-40.
2009: Daniele Catalucci; Deng-Hong Zhang; Jaime DeSantiago; Franck Aimond; Guillaume Barbara; Jean Chemin; Désiré Bonci; Eckard Picht; Francesca Rusconi; Nancy Dalton; Kirk L Peterson; Sylvain Richard; Donald M Bers; Joan Heller Brown; Gianluigi Condorelli
Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability.
The Journal of cell biology 2009;184(6):923-33.
2009: Donald M Bers; Sanda Despa
Na+ transport in cardiac myocytes; Implications for excitation-contraction coupling.
IUBMB life 2009;61(3):215-21.
2009: Jason R Waggoner; Kenneth S Ginsburg; Bryan Mitton; Kobra Haghighi; Jeffrey Robbins; Donald M Bers; Evangelia G Kranias
Phospholamban overexpression in rabbit ventricular myocytes does not alter sarcoplasmic reticulum Ca transport.
American journal of physiology. Heart and circulatory physiology 2009;296(3):H698-703.
2009: Donald M Bers
Some just can't say enough in the new JMCC Point-Counterpoint feature.
Journal of molecular and cellular cardiology 2009;46(2):117.
2009: Shanshan Liang; Fan Yang; Cheng Zhou; Yue Wang; Shao Li; C K Sun; Jose Luis Puglisi; Donald M Bers; Changsen Sun; Jie Zheng
Temperature-dependent activation of neurons by continuous near-infrared laser.
Cell biochemistry and biophysics 2009;53(1):33-42.
2008: Jeffrey J Saucerman; Donald M Bers
Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes.
Biophysical journal 2008;95(10):4597-612.
2008: Qiujing Song; Jeffrey J Saucerman; Julie Bossuyt; Donald M Bers
Differential integration of Ca2+-calmodulin signal in intact ventricular myocytes at low and high affinity Ca2+-calmodulin targets.
The Journal of biological chemistry 2008;283(46):31531-40.
2008: Sabine Huke; Donald M Bers
Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes.
Biochemical and biophysical research communications 2008;376(1):80-5.
2008: Aleksey V Zima; Eckard Picht; Donald M Bers; Lothar A Blatter
Termination of cardiac Ca2+ sparks: role of intra-SR [Ca2+], release flux, and intra-SR Ca2+ diffusion.
Circulation research 2008;103(8):e105-15.
2008: Yoram Rudy; Michael J Ackerman; Donald M Bers; colleen clancy; Steven R Houser; Barry London; Andrew D McCulloch; DA Przywara; Randall L Rasmusson; R John Solaro; Natalia A Trayanova; David Van Wagoner; András Varró; James N Weiss; David Austin Lathrop
Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary.
Circulation 2008;118(11):1202-11.
2008: JJ Rice; Fei Wang; Donald M Bers; Pieter P de Tombe
Approximate model of cooperative activation and crossbridge cycling in cardiac muscle using ordinary differential equations.
Biophysical journal 2008;95(5):2368-90.
2008: Dmitry Terentyev; Zuzana Kubalova; Giorgio Valle; Alessandra Nori; Srikanth Vedamoorthyrao; Radmila Terentyeva; Serge Viatchenko-Karpinski; Donald M Bers; Simon C Williams; Pompeo Volpe; Sandor Gyorke
Modulation of SR Ca release by luminal Ca and calsequestrin in cardiac myocytes: effects of CASQ2 mutations linked to sudden cardiac death.
Biophysical journal 2008;95(4):2037-48.
2008: Jaime Desantiago; Xun Ai; Mohammed Islam; Georgia Acuna; Mark T Ziolo; Donald M Bers; Steven M Pogwizd
Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load.
Circulation research 2008;102(11):1389-97.
2008: Donald M Bers; David Eisner
Point/counterpoint: a new feature in the JMCC.
Journal of molecular and cellular cardiology 2008;44(6):949.
2008: Eileen M Kelly; Zhanjia Hou; Julie Bossuyt; Donald M Bers; Seth L Robia
Phospholamban oligomerization, quaternary structure, and sarco(endo)plasmic reticulum calcium ATPase binding measured by fluorescence resonance energy transfer in living cells.
The Journal of biological chemistry 2008;283(18):12202-11.
2008: Sanda Despa; Amy L Tucker; Donald M Bers
Phospholemman-mediated activation of Na/K-ATPase limits [Na]i and inotropic state during beta-adrenergic stimulation in mouse ventricular myocytes.
Circulation 2008;117(14):1849-55.
2008: Julie Bossuyt; Kathryn Helmstadter; Xu Wu; Hugh Clements-Jewery; Robert S Haworth; Metin Avkiran; Jody L Martin; Steven M Pogwizd; Donald M Bers
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure.
Circulation research 2008;102(6):695-702.
2008: Aleksey V Zima; Eckard Picht; Donald M Bers; Lothar A Blatter
Partial inhibition of sarcoplasmic reticulum ca release evokes long-lasting ca release events in ventricular myocytes: role of luminal ca in termination of ca release.
Biophysical journal 2008;94(5):1867-79.
2008: Donald M Bers
Calcium cycling and signaling in cardiac myocytes.
Annual review of physiology 2008;70():23-49.
2007: Eleonora Grandi; Jose L Puglisi; Stefan Wagner; Lars S Maier; Stefano Severi; Donald M Bers
Simulation of Ca-calmodulin-dependent protein kinase II on rabbit ventricular myocyte ion currents and action potentials.
Biophysical journal 2007;93(11):3835-47.
2007: Tong Zhang; Michael Kohlhaas; Johannes Backs; Shikha Mishra; William Phillips; Nataliya Dybkova; Shurong Chang; Haiyun Ling; Donald M Bers; Lars S Maier; Eric N Olson; Joan Heller Brown
CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses.
The Journal of biological chemistry 2007;282(48):35078-87.
2007: Tao Guo; Xun Ai; Thomas R Shannon; Steven M Pogwizd; Donald M Bers
Intra-sarcoplasmic reticulum free [Ca2+] and buffering in arrhythmogenic failing rabbit heart.
Circulation research 2007;101(8):802-10.
2007: Julio Altamirano; Donald M Bers
Voltage dependence of cardiac excitation-contraction coupling: unitary Ca2+ current amplitude and open channel probability.
Circulation research 2007;101(6):590-7.
2007: Donald M Bers
Going to cAMP just got more complicated.
The Journal of physiology 2007;583(Pt 2):415-6.
2007: Eckard Picht; Aleksey V Zima; Lothar A Blatter; Donald M Bers
SparkMaster: automated calcium spark analysis with ImageJ.
American journal of physiology. Cell physiology 2007;293(3):C1073-81.
2007: Erin R Higgins; Pranay Goel; Jose L Puglisi; Donald M Bers; Mark Cannell; James Sneyd
Modelling calcium microdomains using homogenisation.
Journal of theoretical biology 2007;247(4):623-44.
2007: Julio Altamirano; Donald M Bers
Effect of intracellular Ca2+ and action potential duration on L-type Ca2+ channel inactivation and recovery from inactivation in rabbit cardiac myocytes.
American journal of physiology. Heart and circulatory physiology 2007;293(1):H563-73.
2007: Sanda Despa; Donald M Bers
Functional analysis of Na+/K+-ATPase isoform distribution in rat ventricular myocytes.
American journal of physiology. Cell physiology 2007;293(1):C321-7.
2007: Emir Islamovic; Alexis Duncan; Donald M Bers; William T Gerthoffer; Ruben Mestril
Importance of small heat shock protein 20 (hsp20) C-terminal extension in cardioprotection.
Journal of molecular and cellular cardiology 2007;42(4):862-9.
2007: Xu Wu; Donald M Bers
Free and bound intracellular calmodulin measurements in cardiac myocytes.
Cell calcium 2007;41(4):353-64.
2007: Donald M Bers; Kenneth S Ginsburg
Na:Ca stoichiometry and cytosolic Ca-dependent activation of NCX in intact cardiomyocytes.
Annals of the New York Academy of Sciences 2007;1099():326-38.
2007: Lars S Maier; Donald M Bers; Joan Heller Brown
Calmodulin and Ca2+/calmodulin kinases in the heart - physiology and pathophysiology.
Cardiovascular research 2007;73(4):629-30.
2007: Sabine Huke; Donald M Bers
Temporal dissociation of frequency-dependent acceleration of relaxation and protein phosphorylation by CaMKII.
Journal of molecular and cellular cardiology 2007;42(3):590-9.
2007: Lars S Maier; Donald M Bers
Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation-contraction coupling in the heart.
Cardiovascular research 2007;73(4):631-40.
2007: Jerald Curran; Mark J Hinton; Eduardo Ríos; Donald M Bers; Thomas R Shannon
Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.
Circulation research 2007;100(3):391-8.
2007: Qunying Yuan; Guo-Chang Fan; Min Dong; Beth Altschafl; Abhinav Diwan; Xiaoping Ren; Harvey H Hahn; Wen Zhao; Jason R Waggoner; Larry R Jones; W Keith Jones; Donald M Bers; Gerald W Dorn; Hong-Sheng Wang; Héctor H Valdivia; Guoxiang Chu; Evangelia G Kranias
Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity.
Circulation 2007;115(3):300-9.
2007: Carlo G Tocchetti; Wang Wang; Jeffrey P Froehlich; Sabine Huke; Miguel A Aon; Gerald M Wilson; Giulietta Di Benedetto; Brian O'Rourke; Wei Dong Gao; David A Wink; John P Toscano; Manuela Zaccolo; Donald M Bers; Hector H Valdivia; Heping Cheng; David A Kass; Nazareno Paolocci
Nitroxyl improves cellular heart function by directly enhancing cardiac sarcoplasmic reticulum Ca2+ cycling.
Circulation research 2007;100(1):96-104.
2007: Evangelia G Kranias; Donald M Bers
Calcium and cardiomyopathies.
Sub-cellular biochemistry 2007;45():523-37.
2007: José Luis Puglisi; William H Wehrmacher; Harry L Messmore; Donald M Bers
Pulmonary arterial hypertension.
Comprehensive therapy 2007;33(4):231-6.
2007: Roger G Berry; Sanda Despa; William Fuller; Donald M Bers; Michael J Shattock
Differential distribution and regulation of mouse cardiac Na+/K+-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes.
Cardiovascular research 2007;73(1):92-100.
2007: Eckard Picht; Jaime DeSantiago; Sabine Huke; Marcia A Kaetzel; John R Dedman; Donald M Bers
CaMKII inhibition targeted to the sarcoplasmic reticulum inhibits frequency-dependent acceleration of relaxation and Ca2+ current facilitation.
Journal of molecular and cellular cardiology 2007;42(1):196-205.
2006: Fei Han; Julie Bossuyt; Sanda Despa; Amy L Tucker; Donald M Bers
Phospholemman phosphorylation mediates the protein kinase C-dependent effects on Na+/K+ pump function in cardiac myocytes.
Circulation research 2006;99(12):1376-83.
2006: Stefan Wagner; Nataliya Dybkova; Eva C L Rasenack; Claudius Jacobshagen; Larissa Fabritz; Paulus Kirchhof; Sebastian K G Maier; Tong Zhang; Gerd Hasenfuss; Joan Heller Brown; Donald M Bers; Lars S Maier
Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels.
The Journal of clinical investigation 2006;116(12):3127-38.
2006: Donald M Bers
Altered cardiac myocyte Ca regulation in heart failure.
Physiology (Bethesda, Md.) 2006;21():380-7.
2006: Donald M Bers
The beat goes on: diastolic noise that just won't quit.
Circulation research 2006;99(9):921-3.
2006: Julie Bossuyt; Sanda Despa; Jody L Martin; Donald M Bers
Phospholemman phosphorylation alters its fluorescence resonance energy transfer with the Na/K-ATPase pump.
The Journal of biological chemistry 2006;281(43):32765-73.
2006: Donald M Bers; Sanda Despa; Julie Bossuyt
Regulation of Ca2+ and Na+ in normal and failing cardiac myocytes.
Annals of the New York Academy of Sciences 2006;1080():165-77.
2006: Eckard Picht; Jaime DeSantiago; Lothar A Blatter; Donald M Bers
Cardiac alternans do not rely on diastolic sarcoplasmic reticulum calcium content fluctuations.
Circulation research 2006;99(7):740-8.
2006: Julio Altamirano; Yanxia Li; Jaime DeSantiago; Valentino Piacentino; Steven R Houser; Donald M Bers
The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+-Ca2+ exchanger function.
The Journal of physiology 2006;575(Pt 3):845-54.
2006: Lars S Maier; Mark T Ziolo; Julie Bossuyt; Anthony Persechini; Ruben Mestril; Donald M Bers
Dynamic changes in free Ca-calmodulin levels in adult cardiac myocytes.
Journal of molecular and cellular cardiology 2006;41(3):451-8.
2006: Tao Guo; Tong Zhang; Ruben Mestril; Donald M Bers
Ca2+/Calmodulin-dependent protein kinase II phosphorylation of ryanodine receptor does affect calcium sparks in mouse ventricular myocytes.
Circulation research 2006;99(4):398-406.
2006: Xu Wu; Donald M Bers
Sarcoplasmic reticulum and nuclear envelope are one highly interconnected Ca2+ store throughout cardiac myocyte.
Circulation research 2006;99(3):283-91.
2006: Donald M Bers
Cardiac ryanodine receptor phosphorylation: target sites and functional consequences.
The Biochemical journal 2006;396(1):e1-3.
2006: Kimberly N Gregory; Kenneth S Ginsburg; Ilona Bodi; Harvey Hahn; Yehia Marreez; Qiujing Song; Prabhu A Padmanabhan; Bryan Mitton; Jason R Waggoner; Federica del Monte; Woo Jin Park; Gerald W Dorn; Donald M Bers; Evangelia G Kranias
Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function.
Journal of molecular and cellular cardiology 2006;40(5):653-65.
2006: Xu Wu; Tong Zhang; Julie Bossuyt; Xiaodong Li; Timothy A McKinsey; John R Dedman; Eric N Olson; Ju Chen; Joan Heller Brown; Donald M Bers
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling.
The Journal of clinical investigation 2006;116(3):675-82.
2006: Junhui Sun; Eckard Picht; Kenneth S Ginsburg; Donald M Bers; CHARLES STEENBERGEN; Elizabeth Murphy
Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel alpha1 subunit and reduced ischemia/reperfusion injury.
Circulation research 2006;98(3):403-11.
2006: Michael Kohlhaas; Tong Zhang; Tim Seidler; Darya Zibrova; Nataliya Dybkova; Astrid Steen; Stefan Wagner; Lu Chen; Joan Heller Brown; Donald M Bers; Lars S Maier
Increased sarcoplasmic reticulum calcium leak but unaltered contractility by acute CaMKII overexpression in isolated rabbit cardiac myocytes.
Circulation research 2006;98(2):235-44.
2006: Yong Ji; Wen Zhao; Bailing Li; Jaime DeSantiago; Eckard Picht; Marcia A Kaetzel; Jo El J Schultz; Evangelia G Kranias; Donald M Bers; John R Dedman
Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility.
American journal of physiology. Heart and circulatory physiology 2006;290(2):H599-606.
2006: Timothy P Remus; Aleksey V Zima; Julie Bossuyt; Dan J Bare; Jody L Martin; Lothar A Blatter; Donald M Bers; Gregory A Mignery
Biosensors to measure inositol 1,4,5-trisphosphate concentration in living cells with spatiotemporal resolution.
The Journal of biological chemistry 2006;281(1):608-16.
2006: Donald M Bers; Sanda Despa
Cardiac myocytes Ca2+ and Na+ regulation in normal and failing hearts.
Journal of pharmacological sciences 2006;100(5):315-22.
2005: Xun Ai; Jerry W Curran; Thomas R Shannon; Donald M Bers; Steven M Pogwizd
Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure.
Circulation research 2005;97(12):1314-22.
2005: Kenneth S Ginsburg; Donald M Bers
Isoproterenol does not enhance Ca-dependent Na/Ca exchange current in intact rabbit ventricular myocytes.
Journal of molecular and cellular cardiology 2005;39(6):972-81.
2005: Thomas R Shannon; Fei Wang; Donald M Bers
Regulation of cardiac sarcoplasmic reticulum Ca release by luminal [Ca] and altered gating assessed with a mathematical model.
Biophysical journal 2005;89(6):4096-110.
2005: Fabien Brette; Sanda Despa; Donald M Bers; Clive H Orchard
Spatiotemporal characteristics of SR Ca(2+) uptake and release in detubulated rat ventricular myocytes.
Journal of molecular and cellular cardiology 2005;39(5):804-12.
2005: T R Shannon; Donald M Bers; Lothar A Blatter; Ernst Niggli
Confocal imaging of CICR events from isolated and immobilized SR vesicles.
Cell calcium 2005;38(5):497-505.
2005: Julie Bossuyt; Xun Ai; J Randall Moorman; Steven M Pogwizd; Donald M Bers
Expression and phosphorylation of the na-pump regulatory subunit phospholemman in heart failure.
Circulation research 2005;97(6):558-65.
2005: Sanda Despa; Julie Bossuyt; Fei Han; Kenneth S Ginsburg; Li-Guo Jia; Howard C Kutchai; Amy L Tucker; Donald M Bers
Phospholemman-phosphorylation mediates the beta-adrenergic effects on Na/K pump function in cardiac myocytes.
Circulation research 2005;97(3):252-9.
2005: Donald M Bers; Tao Guo
Calcium signaling in cardiac ventricular myocytes.
Annals of the New York Academy of Sciences 2005;1047():86-98.
2005: Atsushi Sanbe; Jeanne James; Volkan Tuzcu; Selman Nas; Lisa Martin; James Gulick; Hanna Osinska; Sadayappan Sakthivel; Raisa Klevitsky; Kenneth S Ginsburg; Donald M Bers; Bruce Zinman; Edward G Lakatta; Jeffrey Robbins
Transgenic rabbit model for human troponin I-based hypertrophic cardiomyopathy.
Circulation 2005;111(18):2330-8.
2005: Mark T Ziolo; Jody L Martin; Julie Bossuyt; Donald M Bers; Steven M Pogwizd
Adenoviral gene transfer of mutant phospholamban rescues contractile dysfunction in failing rabbit myocytes with relatively preserved SERCA function.
Circulation research 2005;96(8):815-7.
2005: Dan J Bare; Claudia S Kettlun; Mei Liang; Donald M Bers; Gregory A Mignery
Cardiac type 2 inositol 1,4,5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II.
The Journal of biological chemistry 2005;280(16):15912-20.
2005: Donald M Bers
Beyond beta blockers.
Nature medicine 2005;11(4):379-80.
2005: William H Wehrmacher; José Luis Puglisi; Donald M Bers; Harry L Messmore
Sudden unexpected death.
Comprehensive therapy 2005;31(3):176-80.
2004: Nils Teucher; Jürgen Prestle; Tim Seidler; Susan Currie; Elspeth B Elliott; Deborah F Reynolds; Peter Schott; Stefan Wagner; Harald Kogler; Giuseppe Inesi; Donald M Bers; Gerd Hasenfuss; Godfrey L Smith
Excessive sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression causes increased sarcoplasmic reticulum Ca2+ uptake but decreases myocyte shortening.
Circulation 2004;110(23):3553-9.
2004: Thomas R Shannon; Fei Wang; José Puglisi; Christopher Weber; Donald M Bers
A mathematical treatment of integrated Ca dynamics within the ventricular myocyte.
Biophysical journal 2004;87(5):3351-71.
2004: Rosana A Bassani; Julio Altamirano; José L Puglisi; Donald M Bers
Action potential duration determines sarcoplasmic reticulum Ca2+ reloading in mammalian ventricular myocytes.
The Journal of physiology 2004;559(Pt 2):593-609.
2004: Khuram W Chaudhary; Eric I Rossman; Valentino Piacentino; Agnes Kenessey; Chris Weber; John P Gaughan; Kaie Ojamaa; Irwin Klein; Donald M Bers; Steven R Houser; Kenneth B Margulies
Altered myocardial Ca2+ cycling after left ventricular assist device support in the failing human heart.
Journal of the American College of Cardiology 2004;44(4):837-45.
2004: Sanda Despa; Jens Kockskämper; Lothar A Blatter; Donald M Bers
Na/K pump-induced [Na](i) gradients in rat ventricular myocytes measured with two-photon microscopy.
Biophysical journal 2004;87(2):1360-8.
2004: Donald M Bers
Macromolecular complexes regulating cardiac ryanodine receptor function.
Journal of molecular and cellular cardiology 2004;37(2):417-29.
2004: Jose L Puglisi; Fei Wang; Donald M Bers
Modeling the isolated cardiac myocyte.
Progress in biophysics and molecular biology 2004;85(2-3):163-78.
2004: Thomas R Shannon; Donald M Bers
Integrated Ca2+ management in cardiac myocytes.
Annals of the New York Academy of Sciences 2004;1015():28-38.
2004: Mark T Ziolo; Lars S Maier; Valentino Piacentino; Julie Bossuyt; Steven R Houser; Donald M Bers
Myocyte nitric oxide synthase 2 contributes to blunted beta-adrenergic response in failing human hearts by decreasing Ca2+ transients.
Circulation 2004;109(15):1886-91.
2004: Kenneth S Ginsburg; Donald M Bers
Modulation of excitation-contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger.
The Journal of physiology 2004;556(Pt 2):463-80.
2004: Steven M Pogwizd; Donald M Bers
Cellular basis of triggered arrhythmias in heart failure.
Trends in cardiovascular medicine 2004;14(2):61-6.
2004: Jaime DeSantiago; Lars S Maier; Donald M Bers
Phospholamban is required for CaMKII-dependent recovery of Ca transients and SR Ca reuptake during acidosis in cardiac myocytes.
Journal of molecular and cellular cardiology 2004;36(1):67-74.
2003: Christopher R Weber; Valentino Piacentino; Steven R Houser; Donald M Bers
Dynamic regulation of sodium/calcium exchange function in human heart failure.
Circulation 2003;108(18):2224-9.
2003: Sanda Despa; Fabien Brette; Clive H Orchard; Donald M Bers
Na/Ca exchange and Na/K-ATPase function are equally concentrated in transverse tubules of rat ventricular myocytes.
Biophysical journal 2003;85(5):3388-96.
2003: Thomas R Shannon; Steven M Pogwizd; Donald M Bers
Elevated sarcoplasmic reticulum Ca2+ leak in intact ventricular myocytes from rabbits in heart failure.
Circulation research 2003;93(7):592-4.
2003: Donald M Bers; David A Eisner; Hector H Valdivia
Sarcoplasmic reticulum Ca2+ and heart failure: roles of diastolic leak and Ca2+ transport.
Circulation research 2003;93(6):487-90.
2003: Uwe Kirchhefer; Joachim Neumann; Donald M Bers; Igor B Buchwalow; Larissa Fabritz; Gabriela Hanske; Isabel Justus; Burkhard Riemann; Wilhelm Schmitz; Larry R Jones
Impaired relaxation in transgenic mice overexpressing junctin.
Cardiovascular research 2003;59(2):369-79.
2003: Stephen L Lipsius; Donald M Bers
Cardiac pacemaking: I(f) vs. Ca(2+), is it really that simple?
Journal of molecular and cellular cardiology 2003;35(8):891-3.
2003: Thomas R Shannon; Tao Guo; Donald M Bers
Ca2+ scraps: local depletions of free [Ca2+] in cardiac sarcoplasmic reticulum during contractions leave substantial Ca2+ reserve.
Circulation research 2003;93(1):40-5.
2003: Mark T Ziolo; Donald M Bers
The real estate of NOS signaling: location, location, location.
Circulation research 2003;92(12):1279-81.
2003: Sanda Despa; Donald M Bers
Na/K pump current and [Na](i) in rabbit ventricular myocytes: local [Na](i) depletion and Na buffering.
Biophysical journal 2003;84(6):4157-66.
2003: Christopher R Weber; Kenneth S Ginsburg; Donald M Bers
Cardiac submembrane [Na+] transients sensed by Na+-Ca2+ exchange current.
Circulation research 2003;92(9):950-2.
2003: Tong Zhang; Lars S Maier; Nancy Dalton; Shigeki Miyamoto; John Ross; Donald M Bers; Joan Heller Brown
The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure.
Circulation research 2003;92(8):912-9.
2003: Lars S Maier; Tong Zhang; Lu Chen; Jaime DeSantiago; Joan Heller Brown; Donald M Bers
Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release.
Circulation research 2003;92(8):904-11.
2003: Angela G Brittsan; Kenneth S Ginsburg; Guoxiang Chu; Atsuko Yatani; Beata M Wolska; Albrecht G Schmidt; Michio Asahi; David H MacLennan; Donald M Bers; Evangelia G Kranias
Chronic SR Ca2+-ATPase inhibition causes adaptive changes in cellular Ca2+ transport.
Circulation research 2003;92(7):769-76.
2003: Donald M Bers
Dynamic imaging in living cells: windows into local signaling.
Science's STKE : signal transduction knowledge environment 2003;2003(177):PE13.
2003: Valentino Piacentino; Christopher R Weber; Xiongwen Chen; Jutta Weisser-Thomas; Kenneth B Margulies; Donald M Bers; Steven R Houser
Cellular basis of abnormal calcium transients of failing human ventricular myocytes.
Circulation research 2003;92(6):651-8.
2003: Dirk von Lewinski; Burkhard Stumme; Lars S Maier; Claus Luers; Donald M Bers; Burkert Pieske
Stretch-dependent slow force response in isolated rabbit myocardium is Na+ dependent.
Cardiovascular research 2003;57(4):1052-61.
2003: Donald M Bers; William H Barry; Sanda Despa
Intracellular Na+ regulation in cardiac myocytes.
Cardiovascular research 2003;57(4):897-912.
2003: Steven M Pogwizd; Karin R Sipido; Fons Verdonck; Donald M Bers
Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis.
Cardiovascular research 2003;57(4):887-96.
2003: Burkert Pieske; Steven R Houser; Gerd Hasenfuss; Donald M Bers
Sodium and the heart: a hidden key factor in cardiac regulation.
Cardiovascular research 2003;57(4):871-2.
2002: Donald M Bers; Christopher R Weber
Na/Ca exchange function in intact ventricular myocytes.
Annals of the New York Academy of Sciences 2002;976():500-12.
2002: Christopher R Weber; Valentino Piacentino; Kenneth B Margulies; Donald M Bers; Steven R Houser
Calcium influx via I(NCX) is favored in failing human ventricular myocytes.
Annals of the New York Academy of Sciences 2002;976():478-9.
2002: Valentino Piacentino; Christopher R Weber; John P Gaughan; Kenneth B Margulies; Donald M Bers; Steven R Houser
Modulation of contractility in failing human myocytes by reverse-mode Na/Ca exchange.
Annals of the New York Academy of Sciences 2002;976():466-71.
2002: Steven M Pogwizd; Donald M Bers
Na/Ca exchange in heart failure: contractile dysfunction and arrhythmogenesis.
Annals of the New York Academy of Sciences 2002;976():454-65.
2002: Kenneth S Ginsburg; Christopher R Weber; Sanda Despa; Donald M Bers
Simultaneous measurement of [Na]i, [Ca]i, and I(NCX) in intact cardiac myocytes.
Annals of the New York Academy of Sciences 2002;976():157-8.
2002: Thomas R Shannon; Kenneth S Ginsburg; Donald M Bers
Quantitative assessment of the SR Ca2+ leak-load relationship.
Circulation research 2002;91(7):594-600.
2002: Zhuan Zhou; Donald M Bers
Time course of action of antagonists of mitochondrial Ca uptake in intact ventricular myocytes.
Pflügers Archiv : European journal of physiology 2002;445(1):132-8.
2002: Jaime DeSantiago; Lars S Maier; Donald M Bers
Frequency-dependent acceleration of relaxation in the heart depends on CaMKII, but not phospholamban.
Journal of molecular and cellular cardiology 2002;34(8):975-84.
2002: Lars S Maier; Donald M Bers
Calcium, calmodulin, and calcium-calmodulin kinase II: heartbeat to heartbeat and beyond.
Journal of molecular and cellular cardiology 2002;34(8):919-39.
2002: Rolf Brandes; Donald M Bers
Simultaneous measurements of mitochondrial NADH and Ca(2+) during increased work in intact rat heart trabeculae.
Biophysical journal 2002;83(2):587-604.
2002: Donald M Bers
Sarcoplasmic reticulum Ca release in intact ventricular myocytes.
Frontiers in bioscience : a journal and virtual library 2002;7():d1697-711.
2002: Sanda Despa; Mohammed A Islam; Christopher R Weber; Steven M Pogwizd; Donald M Bers
Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged.
Circulation 2002;105(21):2543-8.
2002: Donald M Bers
Cardiac Na/Ca exchange function in rabbit, mouse and man: what's the difference?
Journal of molecular and cellular cardiology 2002;34(4):369-73.
2002: Yanxia Li; Evangelia G Kranias; Gregory A Mignery; Donald M Bers
Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes.
Circulation research 2002;90(3):309-16.
2002: Sanda Despa; Mohammed A Islam; Steven M Pogwizd; Donald M Bers
Intracellular [Na+] and Na+ pump rate in rat and rabbit ventricular myocytes.
The Journal of physiology 2002;539(Pt 1):133-43.
2002: Christopher R Weber; Valentino Piacentino; Kenneth S Ginsburg; Steven R Houser; Donald M Bers
Na(+)-Ca(2+) exchange current and submembrane [Ca(2+)] during the cardiac action potential.
Circulation research 2002;90(2):182-9.
2002: Donald M Bers
Calcium and cardiac rhythms: physiological and pathophysiological.
Circulation research 2002;90(1):14-7.
2002: Donald M Bers
Cardiac excitation-contraction coupling.
Nature 2002;415(6868):198-205.
2002: Donald M Bers; Steven M Pogwizd; Klaus Schlotthauer
Upregulated Na/Ca exchange is involved in both contractile dysfunction and arrhythmogenesis in heart failure.
Basic research in cardiology 2002;97 Suppl 1():I36-42.
2002: Steven M Pogwizd; Donald M Bers
Calcium cycling in heart failure: the arrhythmia connection.
Journal of cardiovascular electrophysiology 2002;13(1):88-91.
2001: Mark T Ziolo; H Katoh; Donald M Bers
Expression of inducible nitric oxide synthase depresses beta-adrenergic-stimulated calcium release from the sarcoplasmic reticulum in intact ventricular myocytes.
Circulation 2001;104(24):2961-6.
2001: Mark T Ziolo; H Katoh; Donald M Bers
Positive and negative effects of nitric oxide on Ca(2+) sparks: influence of beta-adrenergic stimulation.
American journal of physiology. Heart and circulatory physiology 2001;281(6):H2295-303.
2001: J L Puglisi; Donald M Bers
LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport.
American journal of physiology. Cell physiology 2001;281(6):C2049-60.
2001: Yanxia Li; Donald M Bers
A cardiac dihydropyridine receptor II-III loop peptide inhibits resting Ca(2+) sparks in ferret ventricular myocytes.
The Journal of physiology 2001;537(Pt 1):17-26.
2001: Donald M Bers; Mark T Ziolo
When is cAMP not cAMP? Effects of compartmentalization.
Circulation research 2001;89(5):373-5.
2001: Steven M Pogwizd; Klaus Schlotthauer; L Li; W Yuan; Donald M Bers
Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness.
Circulation research 2001;88(11):1159-67.
2001: T R Shannon; G Chu; Evangelia G Kranias; Donald M Bers
Phospholamban decreases the energetic efficiency of the sarcoplasmic reticulum Ca pump.
The Journal of biological chemistry 2001;276(10):7195-201.
2001: Christopher R Weber; Kenneth S Ginsburg; K D Philipson; Thomas R Shannon; Donald M Bers
Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes.
The Journal of general physiology 2001;117(2):119-31.
2000: Lars S Maier; Donald M Bers; Burkert Pieske
Differences in Ca(2+)-handling and sarcoplasmic reticulum Ca(2+)-content in isolated rat and rabbit myocardium.
Journal of molecular and cellular cardiology 2000;32(12):2249-58.
2000: Konrad Frank; Carola Gabriella Tilgmann; T R Shannon; Donald M Bers; Evangelia G Kranias
Regulatory role of phospholamban in the efficiency of cardiac sarcoplasmic reticulum Ca2+ transport.
Biochemistry 2000;39(46):14176-82.
2000: K Schlotthauer; Donald M Bers
Sarcoplasmic reticulum Ca(2+) release causes myocyte depolarization. Underlying mechanism and threshold for triggered action potentials.
Circulation research 2000;87(9):774-80.
2000: Donald M Bers
Calcium fluxes involved in control of cardiac myocyte contraction.
Circulation research 2000;87(4):275-81.
2000: H Katoh; Klaus Schlotthauer; Donald M Bers
Transmission of information from cardiac dihydropyridine receptor to ryanodine receptor: evidence from BayK 8644 effects on resting Ca(2+) sparks.
Circulation research 2000;87(2):106-11.
2000: Hiroshi Satoh; K S Ginsburg; K Qing; Hajime Terada; Hideharu Hayashi; Donald M Bers
KB-R7943 block of Ca(2+) influx via Na(+)/Ca(2+) exchange does not alter twitches or glycoside inotropy but prevents Ca(2+) overload in rat ventricular myocytes.
Circulation 2000;101(12):1441-6.
2000: L Li; Jaime DeSantiago; G Chu; Evangelia G Kranias; Donald M Bers
Phosphorylation of phospholamban and troponin I in beta-adrenergic-induced acceleration of cardiac relaxation.
American journal of physiology. Heart and circulatory physiology 2000;278(3):H769-79.
2000: Z Zhou; Donald M Bers
Ca2+ influx via the L-type Ca2+ channel during tail current and above current reversal potential in ferret ventricular myocytes.
The Journal of physiology 2000;523 Pt 1():57-66.
2000: Thomas R Shannon; Kenneth S Ginsburg; Donald M Bers
Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration.
Biophysical journal 2000;78(1):334-43.
2000: Thomas R Shannon; Kenneth S Ginsburg; Donald M Bers
Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes.
Biophysical journal 2000;78(1):322-33.
1999: Steven M Pogwizd; M Qi; W Yuan; Allen M Samarel; Donald M Bers
Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure.
Circulation research 1999;85(11):1009-19.
1999: J L Puglisi; W Yuan; J W Bassani; Donald M Bers
Ca(2+) influx through Ca(2+) channels in rabbit ventricular myocytes during action potential clamp: influence of temperature.
Circulation research 1999;85(6):e7-e16.
1999: PS Haddock; William A Coetzee; E Cho; L Porter; H Katoh; Donald M Bers; M Saleet Jafri; Michael Artman
Subcellular [Ca2+]i gradients during excitation-contraction coupling in newborn rabbit ventricular myocytes.
Circulation research 1999;85(5):415-27.
1999: R Brandes; Donald M Bers
Analysis of the mechanisms of mitochondrial NADH regulation in cardiac trabeculae.
Biophysical journal 1999;77(3):1666-82.
1999: Burkert Pieske; Lars S Maier; Donald M Bers; Gerd Hasenfuss
Ca2+ handling and sarcoplasmic reticulum Ca2+ content in isolated failing and nonfailing human myocardium.
Circulation research 1999;85(1):38-46.
1999: Donald M Bers; Edward Perez-Reyes
Ca channels in cardiac myocytes: structure and function in Ca influx and intracellular Ca release.
Cardiovascular research 1999;42(2):339-60.
1998: H Satoh; H Katoh; P Velez; Michael Fill; Donald M Bers
Bay K 8644 increases resting Ca2+ spark frequency in ferret ventricular myocytes independent of Ca influx: contrast with caffeine and ryanodine effects.
Circulation research 1998;83(12):1192-204.
1998: Guoxiang Chu; L Li; Yoji Sato; Judy M Harrer; Vivek J Kadambi; Brian D Hoit; Donald M Bers; Evangelia G Kranias
Pentameric assembly of phospholamban facilitates inhibition of cardiac function in vivo.
The Journal of biological chemistry 1998;273(50):33674-80.
1998: B M Cadre; M Qi; Diane M Eble; Thomas R Shannon; Donald M Bers; Allen M Samarel
Cyclic stretch down-regulates calcium transporter gene expression in neonatal rat ventricular myocytes.
Journal of molecular and cellular cardiology 1998;30(11):2247-59.
1998: Thomas R Shannon; Kenneth S Ginsburg; Donald M Bers
Reverse mode of the sarcoplasmic reticulum Ca pump limits sarcoplasmic reticulum Ca uptake in permeabilized and voltage-clamped myocytes.
Annals of the New York Academy of Sciences 1998;853():350-2.
1998: Donald M Bers; L Li; H Satoh; E McCall
Factors that control sarcoplasmic reticulum calcium release in intact ventricular myocytes.
Annals of the New York Academy of Sciences 1998;853():157-77.
1998: Donald M Bers; Michael Fill
Coordinated feet and the dance of ryanodine receptors.
Science (New York, N.Y.) 1998;281(5378):790-1.
1998: Klaus Schlotthauer; J Schattmann; Donald M Bers; Lars S Maier; U Schütt; K Minami; Hanjörg Just; Gerd Hasenfuss; Burkert Pieske
Frequency-dependent changes in contribution of SR Ca2+ to Ca2+ transients in failing human myocardium assessed with ryanodine.
Journal of molecular and cellular cardiology 1998;30(7):1285-94.
1998: R Brandes; Lars S Maier; Donald M Bers
Regulation of mitochondrial [NADH] by cytosolic [Ca2+] and work in trabeculae from hypertrophic and normal rat hearts.
Circulation research 1998;82(11):1189-98.
1998: Rosana A Bassani; T R Shannon; Donald M Bers
Passive Ca2+ binding in ventricular myocardium of neonatal and adult rats.
Cell calcium 1998;23(6):433-42.
1998: Jörg Hüser; Donald M Bers; Lothar A Blatter
Subcellular properties of [Ca2+]i transients in phospholamban-deficient mouse ventricular cells.
The American journal of physiology 1998;274(5 Pt 2):H1800-11.
1998: Mohammed A Matlib; Z Zhou; S Knight; S Ahmed; K M Choi; Jeanette A Krause Bauer; R Phillips; R Altschuld; Yasuhiro Katsube; Nicholas Sperelakis; Donald M Bers
Oxygen-bridged dinuclear ruthenium amine complex specifically inhibits Ca2+ uptake into mitochondria in vitro and in situ in single cardiac myocytes.
The Journal of biological chemistry 1998;273(17):10223-31.
1998: Lars S Maier; R Brandes; B Pieske; Donald M Bers
Effects of left ventricular hypertrophy on force and Ca2+ handling in isolated rat myocardium.
The American journal of physiology 1998;274(4 Pt 2):H1361-70.
1998: E McCall; Kenneth S Ginsburg; Rosana A Bassani; Thomas R Shannon; M Qi; Allen M Samarel; Donald M Bers
Ca flux, contractility, and excitation-contraction coupling in hypertrophic rat ventricular myocytes.
The American journal of physiology 1998;274(4 Pt 2):H1348-60.
1998: L Li; G Chu; Evangelia G Kranias; Donald M Bers
Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects.
The American journal of physiology 1998;274(4 Pt 2):H1335-47.
1998: Kenneth S Ginsburg; Christopher R Weber; Donald M Bers
Control of maximum sarcoplasmic reticulum Ca load in intact ferret ventricular myocytes. Effects Of thapsigargin and isoproterenol.
The Journal of general physiology 1998;111(4):491-504.
1998: Z Zhou; M A Matlib; Donald M Bers
Cytosolic and mitochondrial Ca2+ signals in patch clamped mammalian ventricular myocytes.
The Journal of physiology 1998;507 ( Pt 2)():379-403.
1998: Diane M Eble; B M Cadre; M Qi; Donald M Bers; Allen M Samarel
Contractile activity modulates atrial natriuretic factor gene expression in neonatal rat ventricular myocytes.
Journal of molecular and cellular cardiology 1998;30(1):55-60.
1997: Duraisamy Balaguru; PS Haddock; J L Puglisi; Donald M Bers; William A Coetzee; Michael Artman
Role of the sarcoplasmic reticulum in contraction and relaxation of immature rabbit ventricular myocytes.
Journal of molecular and cellular cardiology 1997;29(10):2747-57.
1997: Donald M Bers
Ca2+ sparks. Jumping the gap from the cell to cardiac muscle.
Circulation research 1997;81(4):636-8.
1997: Thomas R Shannon; Donald M Bers
Assessment of intra-SR free [Ca] and buffering in rat heart.
Biophysical journal 1997;73(3):1524-31.
1997: Rosana A Bassani; José W M Bassani; S L Lipsius; Donald M Bers
Diastolic SR Ca efflux in atrial pacemaker cells and Ca-overloaded myocytes.
The American journal of physiology 1997;273(2 Pt 2):H886-92.
1997: M Qi; J L Puglisi; Kenneth L Byron; Kaie Ojamaa; I Klein; Donald M Bers; Allen M Samarel
Myosin heavy chain gene expression in neonatal rat heart cells: effects of [Ca2+]i and contractile activity.
The American journal of physiology 1997;273(2 Pt 1):C394-403.
1997: L Li; H Satoh; Kenneth S Ginsburg; Donald M Bers
The effect of Ca(2+)-calmodulin-dependent protein kinase II on cardiac excitation-contraction coupling in ferret ventricular myocytes.
The Journal of physiology 1997;501 ( Pt 1)():17-31.
1997: L M Delbridge; H Satoh; W Yuan; J W Bassani; M Qi; Kenneth S Ginsburg; Allen M Samarel; Donald M Bers
Cardiac myocyte volume, Ca2+ fluxes, and sarcoplasmic reticulum loading in pressure-overload hypertrophy.
The American journal of physiology 1997;272(5 Pt 2):H2425-35.
1997: M Qi; Thomas R Shannon; D E Euler; Donald M Bers; Allen M Samarel
Downregulation of sarcoplasmic reticulum Ca(2+)-ATPase during progression of left ventricular hypertrophy.
The American journal of physiology 1997;272(5 Pt 2):H2416-24.
1997: H Satoh; Lothar A Blatter; Donald M Bers
Effects of [Ca2+]i, SR Ca2+ load, and rest on Ca2+ spark frequency in ventricular myocytes.
The American journal of physiology 1997;272(2 Pt 2):H657-68.
1997: Hiroshi Satoh; Hideharu Hayashi; Lothar A Blatter; Donald M Bers
BayK 8644 increases resting calcium spark frequency in ferret ventricular myocytes.
Heart and vessels 1997;Suppl 12():58-61.
1997: Donald M Bers
Ca transport during contraction and relaxation in mammalian ventricular muscle.
Basic research in cardiology 1997;92 Suppl 1():1-10.
1997: R Brandes; Donald M Bers
Intracellular Ca2+ increases the mitochondrial NADH concentration during elevated work in intact cardiac muscle.
Circulation research 1997;80(1):82-7.
1996: José W M Bassani; Rosana A Bassani; Donald M Bers
A method to estimate mitochondrial Ca2+ uptake in intact cardiac myocytes.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1996;29(12):1699-707.
1996: E McCall; L Li; H Satoh; Thomas R Shannon; Lothar A Blatter; Donald M Bers
Effects of FK-506 on contraction and Ca2+ transients in rat cardiac myocytes.
Circulation research 1996;79(6):1110-21.
1996: Ana Gomez; Heping Cheng; William Lederer; Donald M Bers
Ca2+ diffusion and sarcoplasmic reticulum transport both contribute to [Ca2+]i decline during Ca2+ sparks in rat ventricular myocytes.
The Journal of physiology 1996;496 ( Pt 2)():575-81.
1996: M Qi; José W M Bassani; Donald M Bers; Allen M Samarel
Phorbol 12-myristate 13-acetate alters SR Ca(2+)-ATPase gene expression in cultured neonatal rat heart cells.
The American journal of physiology 1996;271(3 Pt 2):H1031-9.
1996: R Brandes; Donald M Bers
Increased work in cardiac trabeculae causes decreased mitochondrial NADH fluorescence followed by slow recovery.
Biophysical journal 1996;71(2):1024-35.
1996: W Yuan; Kenneth S Ginsburg; Donald M Bers
Comparison of sarcolemmal calcium channel current in rabbit and rat ventricular myocytes.
The Journal of physiology 1996;493 ( Pt 3)():733-46.
1996: J L Puglisi; Rosana A Bassani; José W M Bassani; J N Amin; Donald M Bers
Temperature and relative contributions of Ca transport systems in cardiac myocyte relaxation.
The American journal of physiology 1996;270(5 Pt 2):H1772-8.
1996: Donald M Bers; José W M Bassani; Rosana A Bassani
Na-Ca exchange and Ca fluxes during contraction and relaxation in mammalian ventricular muscle.
Annals of the New York Academy of Sciences 1996;779():430-42.
1996: H Satoh; L M Delbridge; Lothar A Blatter; Donald M Bers
Surface:volume relationship in cardiac myocytes studied with confocal microscopy and membrane capacitance measurements: species-dependence and developmental effects.
Biophysical journal 1996;70(3):1494-504.
1996: E McCall; Donald M Bers
BAY K 8644 depresses excitation-contraction coupling in cardiac muscle.
The American journal of physiology 1996;270(3 Pt 1):C878-84.
1996: Donald M Bers
Measurement of calcium transport in heart using modern approaches.
New horizons (Baltimore, Md.) 1996;4(1):36-44.
1996: L M Delbridge; José W M Bassani; Donald M Bers
Steady-state twitch Ca2+ fluxes and cytosolic Ca2+ buffering in rabbit ventricular myocytes.
The American journal of physiology 1996;270(1 Pt 1):C192-9.
1996: E McCall; L V Hryshko; V M Stiffel; D M Christensen; Donald M Bers
Possible functional linkage between the cardiac dihydropyridine and ryanodine receptor: acceleration of rest decay by Bay K 8644.
Journal of molecular and cellular cardiology 1996;28(1):79-93.
1995: Rosana A Bassani; José W M Bassani; Donald M Bers
Relaxation in ferret ventricular myocytes: role of the sarcolemmal Ca ATPase.
Pflügers Archiv : European journal of physiology 1995;430(4):573-8.
1995: José W M Bassani; W Yuan; Donald M Bers
Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes.
The American journal of physiology 1995;268(5 Pt 1):C1313-9.
1995: Rosana A Bassani; Donald M Bers
Rate of diastolic Ca release from the sarcoplasmic reticulum of intact rabbit and rat ventricular myocytes.
Biophysical journal 1995;68(5):2015-22.
1995: José W M Bassani; Rosana A Bassani; Donald M Bers
Calibration of indo-1 and resting intracellular [Ca]i in intact rabbit cardiac myocytes.
Biophysical journal 1995;68(4):1453-60.
1995: W Yuan; Donald M Bers
Protein kinase inhibitor H-89 reverses forskolin stimulation of cardiac L-type calcium current.
The American journal of physiology 1995;268(3 Pt 1):C651-9.
1995: Rosana A Bassani; A Mattiazzi; Donald M Bers
CaMKII is responsible for activity-dependent acceleration of relaxation in rat ventricular myocytes.
The American journal of physiology 1995;268(2 Pt 2):H703-12.
1995: Donald M Bers; J R Berlin
Kinetics of [Ca]i decline in cardiac myocytes depend on peak [Ca]i.
The American journal of physiology 1995;268(1 Pt 1):C271-7.
1994: Rosana A Bassani; Donald M Bers
Na-Ca exchange is required for rest-decay but not for rest-potentiation of twitches in rabbit and rat ventricular myocytes.
Journal of molecular and cellular cardiology 1994;26(10):1335-47.
1994: Joshua R Berlin; J W Bassani; Donald M Bers
Intrinsic cytosolic calcium buffering properties of single rat cardiac myocytes.
Biophysical journal 1994;67(4):1775-87.
1994: W Yuan; Donald M Bers
Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin-dependent protein kinase.
The American journal of physiology 1994;267(3 Pt 2):H982-93.
1994: A Mattiazzi; L Hove-Madsen; Donald M Bers
Protein kinase inhibitors reduce SR Ca transport in permeabilized cardiac myocytes.
The American journal of physiology 1994;267(2 Pt 2):H812-20.
1994: José W M Bassani; M Qi; Allen M Samarel; Donald M Bers
Contractile arrest increases sarcoplasmic reticulum calcium uptake and SERCA2 gene expression in cultured neonatal rat heart cells.
Circulation research 1994;74(5):991-7.
1994: Rosana A Bassani; José W M Bassani; Donald M Bers
Relaxation in ferret ventricular myocytes: unusual interplay among calcium transport systems.
The Journal of physiology 1994;476(2):295-308.
1994: José W M Bassani; Rosana A Bassani; Donald M Bers
Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms.
The Journal of physiology 1994;476(2):279-93.
1994: Edward Perez-Reyes; W Yuan; X Wei; Donald M Bers
Regulation of the cloned L-type cardiac calcium channel by cyclic-AMP-dependent protein kinase.
FEBS letters 1994;342(2):119-23.
1994: S Baudet; L Hove-Madsen; Donald M Bers
How to make and use calcium-specific mini- and microelectrodes.
Methods in cell biology 1994;40():93-113.
1994: Donald M Bers; C W Patton; R Nuccitelli
A practical guide to the preparation of Ca2+ buffers.
Methods in cell biology 1994;40():3-29.
1993: L Hove-Madsen; Donald M Bers
Sarcoplasmic reticulum Ca2+ uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes.
Circulation research 1993;73(5):820-8.
1993: S Baudet; R Shaoulian; Donald M Bers
Effects of thapsigargin and cyclopiazonic acid on twitch force and sarcoplasmic reticulum Ca2+ content of rabbit ventricular muscle.
Circulation research 1993;73(5):813-9.
1993: Donald M Bers; José W M Bassani; Rosana A Bassani
Competition and redistribution among calcium transport systems in rabbit cardiac myocytes.
Cardiovascular research 1993;27(10):1772-7.
1993: Donald M Bers; Rosana A Bassani; José W M Bassani; S Baudet; L V Hryshko
Paradoxical twitch potentiation after rest in cardiac muscle: increased fractional release of SR calcium.
Journal of molecular and cellular cardiology 1993;25(9):1047-57.
1993: José W M Bassani; Rosana A Bassani; Donald M Bers
Twitch-dependent SR Ca accumulation and release in rabbit ventricular myocytes.
The American journal of physiology 1993;265(2 Pt 1):C533-40.
1993: Donald M Bers; V M Stiffel
Ratio of ryanodine to dihydropyridine receptors in cardiac and skeletal muscle and implications for E-C coupling.
The American journal of physiology 1993;264(6 Pt 1):C1587-93.
1993: L Hove-Madsen; Donald M Bers
Passive Ca buffering and SR Ca uptake in permeabilized rabbit ventricular myocytes.
The American journal of physiology 1993;264(3 Pt 1):C677-86.
1993: José W M Bassani; Rosana A Bassani; Donald M Bers
Ca2+ cycling between sarcoplasmic reticulum and mitochondria in rabbit cardiac myocytes.
The Journal of physiology 1993;460():603-21.
1992: L Hove-Madsen; Donald M Bers
Indo-1 binding to protein in permeabilized ventricular myocytes alters its spectral and Ca binding properties.
Biophysical journal 1992;63(1):89-97.
1992: Rosana A Bassani; José W M Bassani; Donald M Bers
Mitochondrial and sarcolemmal Ca2+ transport reduce [Ca2+]i during caffeine contractures in rabbit cardiac myocytes.
The Journal of physiology 1992;453():591-608.
1992: L V Hryshko; Donald M Bers
Citrate decreases Ca current and changes selectivity of cardiac Ca channels.
Advances in experimental medicine and biology 1992;311():413-5.
1992: L V Hryshko; Donald M Bers
Citrate alters Ca channel gating and selectivity in rabbit ventricular myocytes.
The American journal of physiology 1992;262(1 Pt 1):C191-8.
1991: Donald M Bers
Ca regulation in cardiac muscle.
Medicine and science in sports and exercise 1991;23(10):1157-62.
1991: W Y Lew; L V Hryshko; Donald M Bers
Dihydropyridine receptors are primarily functional L-type calcium channels in rabbit ventricular myocytes.
Circulation research 1991;69(4):1139-45.
1991: Donald M Bers; L V Hryshko; S M Harrison; D D Dawson
Citrate decreases contraction and Ca current in cardiac muscle independent of its buffering action.
The American journal of physiology 1991;260(5 Pt 1):C900-9.
1991: James G Tidball; J E Cederdahl; Donald M Bers
Quantitative analysis of regional variability in the distribution of transverse tubules in rabbit myocardium.
Cell and tissue research 1991;264(2):293-8.
1991: Donald M Bers; A Peskoff
Diffusion around a cardiac calcium channel and the role of surface bound calcium.
Biophysical journal 1991;59(3):703-21.
1991: Donald M Bers
Species differences and the role of sodium-calcium exchange in cardiac muscle relaxation.
Annals of the New York Academy of Sciences 1991;639():375-85.
1990: L V Hryshko; Donald M Bers
Ca current facilitation during postrest recovery depends on Ca entry.
The American journal of physiology 1990;259(3 Pt 2):H951-61.
1990: Donald M Bers; D M Christensen
Functional interconversion of rest decay and ryanodine effects in rabbit and rat ventricle depends on Na/Ca exchange.
Journal of molecular and cellular cardiology 1990;22(6):715-23.
1990: Donald M Bers; William Lederer; J R Berlin
Intracellular Ca transients in rat cardiac myocytes: role of Na-Ca exchange in excitation-contraction coupling.
The American journal of physiology 1990;258(5 Pt 1):C944-54.
1990: S M Harrison; Donald M Bers
Modification of temperature dependence of myofilament Ca sensitivity by troponin C replacement.
The American journal of physiology 1990;258(2 Pt 1):C282-8.
1990: S M Harrison; Donald M Bers
Temperature dependence of myofilament Ca sensitivity of rat, guinea pig, and frog ventricular muscle.
The American journal of physiology 1990;258(2 Pt 1):C274-81.
1990: William Lederer; J R Berlin; N M Cohen; R W Hadley; Donald M Bers; Mark Cannell
Excitation-contraction coupling in heart cells. Roles of the sodium-calcium exchange, the calcium current, and the sarcoplasmic reticulum.
Annals of the New York Academy of Sciences 1990;588():190-206.
1989: L V Hryshko; V Stiffel; Donald M Bers
Rapid cooling contractures as an index of sarcoplasmic reticulum calcium content in rabbit ventricular myocytes.
The American journal of physiology 1989;257(5 Pt 2):H1369-77.
1989: Donald M Bers; John H B Bridge; Kenneth W Spitzer
Intracellular Ca2+ transients during rapid cooling contractures in guinea-pig ventricular myocytes.
The Journal of physiology 1989;417():537-53.
1989: Donald M Bers; John H B Bridge
Relaxation of rabbit ventricular muscle by Na-Ca exchange and sarcoplasmic reticulum calcium pump. Ryanodine and voltage sensitivity.
Circulation research 1989;65(2):334-42.
1989: S M Harrison; Donald M Bers
Correction of proton and Ca association constants of EGTA for temperature and ionic strength.
The American journal of physiology 1989;256(6 Pt 1):C1250-6.
1989: M J Shattock; Donald M Bers
Rat vs. rabbit ventricle: Ca flux and intracellular Na assessed by ion-selective microelectrodes.
The American journal of physiology 1989;256(4 Pt 1):C813-22.
1989: S M Harrison; Donald M Bers
Influence of temperature on the calcium sensitivity of the myofilaments of skinned ventricular muscle from the rabbit.
The Journal of general physiology 1989;93(3):411-28.
1989: Donald M Bers
SR Ca loading in cardiac muscle preparations based on rapid-cooling contractures.
The American journal of physiology 1989;256(1 Pt 1):C109-20.
1988: Donald M Bers; John H B Bridge
Effect of acetylstrophanthidin on twitches, microscopic tension fluctuations and cooling contractures in rabbit ventricle.
The Journal of physiology 1988;404():53-69.
1988: J G Tidball; R Smith; M J Shattock; Donald M Bers
Differences in action potential configuration in ventricular trabeculae correlate with differences in density of transverse tubule-sarcoplasmic reticulum couplings.
Journal of molecular and cellular cardiology 1988;20(6):539-46.
1988: A Peskoff; Donald M Bers
Electrodiffusion of ions approaching the mouth of a conducting membrane channel.
Biophysical journal 1988;53(6):863-75.
1988: Donald M Bers; D M Christensen; T X Nguyen
Can Ca entry via Na-Ca exchange directly activate cardiac muscle contraction?
Journal of molecular and cellular cardiology 1988;20(5):405-14.
1987: M J Shattock; Donald M Bers
Inotropic response to hypothermia and the temperature-dependence of ryanodine action in isolated rabbit and rat ventricular muscle: implications for excitation-contraction coupling.
Circulation research 1987;61(6):761-71.
1987: Donald M Bers
Mechanisms contributing to the cardiac inotropic effect of Na pump inhibition and reduction of extracellular Na.
The Journal of general physiology 1987;90(4):479-504.
1987: Donald M Bers
Ryanodine and the calcium content of cardiac SR assessed by caffeine and rapid cooling contractures.
The American journal of physiology 1987;253(3 Pt 1):C408-15.
1987: K T MacLeod; Donald M Bers
Effects of rest duration and ryanodine on changes of extracellular [Ca] in cardiac muscle from rabbits.
The American journal of physiology 1987;253(3 Pt 1):C398-407.
1987: S M Harrison; Donald M Bers
The effect of temperature and ionic strength on the apparent Ca-affinity of EGTA and the analogous Ca-chelators BAPTA and dibromo-BAPTA.
Biochimica et biophysica acta 1987;925(2):133-43.
1987: M J Shattock; K C Warner; J G Tidball; Donald M Bers
Two different electrophysiological responses to ryanodine: evidence for two populations of muscles isolated from the rabbit right ventricle.
Journal of molecular and cellular cardiology 1987;19(8):751-62.
1987: Donald M Bers; J H Bridge; K T MacLeod
The mechanism of ryanodine action in rabbit ventricular muscle evaluated with Ca-selective microelectrodes and rapid cooling contractures.
Canadian journal of physiology and pharmacology 1987;65(4):610-8.
1986: Donald M Bers; L A Allen; Y Kim
Calcium binding to cardiac sarcolemmal vesicles: potential role as a modifier of contraction.
The American journal of physiology 1986;251(6 Pt 1):C861-71.
1986: C O Malecot; Donald M Bers; B G Katzung
Biphasic contractions induced by milrinone at low temperature in ferret ventricular muscle: role of the sarcoplasmic reticulum and transmembrane calcium influx.
Circulation research 1986;59(2):151-62.
1986: Donald M Bers; K T MacLeod
Cumulative depletions of extracellular calcium in rabbit ventricular muscle monitored with calcium-selective microelectrodes.
Circulation research 1986;58(6):769-82.
1986: J L Sutko; Donald M Bers; J P Reeves
Postrest inotropy in rabbit ventricle: Na+-Ca2+ exchange determines sarcoplasmic reticulum Ca2+ content.
The American journal of physiology 1986;250(4 Pt 2):H654-61.
1985: Donald M Bers
Ca influx and sarcoplasmic reticulum Ca release in cardiac muscle activation during postrest recovery.
The American journal of physiology 1985;248(3 Pt 2):H366-81.
1985: Donald M Bers; K D Philipson; A Peskoff
Calcium at the surface of cardiac plasma membrane vesicles: cation binding, surface charge screening, and Na-Ca exchange.
The Journal of membrane biology 1985;85(3):251-61.
1985: Donald M Bers; D B Merrill
The role of Ca influx in cardiac muscle excitation-contraction coupling. Assessment by extracellular Ca microelectrodes.
Advances in myocardiology 1985;6():49-57.
1983: Donald M Bers
Early transient depletion of extracellular Ca during individual cardiac muscle contractions.
The American journal of physiology 1983;244(3):H462-8.
1982: Donald M Bers
A simple method for the accurate determination of free [Ca] in Ca-EGTA solutions.
The American journal of physiology 1982;242(5):C404-8.
1982: Donald M Bers; D Ellis
Intracellular calcium and sodium activity in sheep heart Purkinje fibres. Effect of changes of external sodium and intracellular pH.
Pflügers Archiv : European journal of physiology 1982;393(2):171-8.
1982: J M Jarmakani; T Nakanishi; B L George; Donald M Bers
Effect of extracellular calcium on myocardial mechanical function in the neonatal rabbit.
Developmental pharmacology and therapeutics 1982;5(1-2):1-13.
1981: Donald M Bers; K D Philipson; G A Langer
Cardiac contractility and sarcolemmal calcium binding in several cardiac muscle preparations.
The American journal of physiology 1981;240(4):H576-83.
1980: K D Philipson; Donald M Bers; A Y Nishimoto
The role of phospholipids in the Ca2+ binding of isolated cardiac sarcolemma.
Journal of molecular and cellular cardiology 1980;12(11):1159-73.
1980: Donald M Bers; K D Philipson; A Y Nishimoto
Sodium-calcium exchange and sidedness of isolated cardiac sarcolemmal vesicles.
Biochimica et biophysica acta 1980;601(2):358-71.
1980: K D Philipson; Donald M Bers; A Y Nishimoto; G A Langer
Binding of Ca2+ and Na+ to sarcolemmal membranes: relation to control of myocardial contractility.
The American journal of physiology 1980;238(3):H373-8.
1979: Donald M Bers; G A Langer
Uncoupling cation effects on cardiac contractility and sarcolemmal Ca2+ binding.
The American journal of physiology 1979;237(3):H332-41.
1979: Donald M Bers
Isolation and characterization of cardiac sarcolemma.
Biochimica et biophysica acta 1979;555(1):131-46.