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Jean-François Pittet
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35
Matthay, Michael
17
Wiener-Kronish, Jeanine
9
Ganter, Michael
9
Modelska, Katharina
8
Mackersie, Robert
8
Roux, Jeremie
8
Folkesson, Hans
7
Sheppard, Dean
7
Pespeni, Melissa
6
McElroy, Mary
6
Brohi, Karim
5
Frank, James
5
Morabito, Diane
5
Kudoh, Ichidai
5
Laffon, Marc
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All Publications
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2009: Chesebro Brian B; Rahn Pamela; Carles Michel; Esmon Charles T; Xu Jun; Brohi Karim; Frith Daniel; Pittet Jean-François; Cohen Mitchell J
Increase in activated protein C mediates acute traumatic coagulopathy in mice.
Shock (Augusta, Ga.) 2009;32(6):659-65.
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2008: Song Yuanlin; Pittet Jean Francois; Huang Xiaozhu; He Hong; Lynch Susan V; Violette Shelia M; Weinreb Paul H; Horan Gerald S; Carmago Amua; Sawa Yoriko; Bernstein Xin Liu; Wiener-Kronish Jeanine P
Role of integrin alphav beta6 in acute lung injury induced by Pseudomonas aeruginosa.
Infection and immunity 2008;76(6):2325-32.
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2008: Brohi Karim; Cohen Mitchell J; Ganter Michael T; Schultz Marcus J; Levi Marcel; Mackersie Robert C; Pittet Jean-François
Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis.
The Journal of trauma 2008;64(5):1211-7; discussion 1217.
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2008: Ganter Michael T; Roux Jérémie; Miyazawa Byron; Howard Marybeth; Frank James A; Su George; Sheppard Dean; Violette Shelia M; Weinreb Paul H; Horan Gerald S; Matthay Michael A; Pittet Jean-François
Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms.
Circulation research 2008;102(7):804-12.
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2008: Ganter Michael T; Cohen Mitchell J; Brohi Karim; Chesebro Brian B; Staudenmayer Kristan L; Rahn Pamela; Christiaans Sarah C; Bir Natasha D; Pittet Jean-François
Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma?
Annals of surgery 2008;247(2):320-6.
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2008: Frank J A; Pittet J-F; Wray C; Matthay M A
Protection from experimental ventilator-induced acute lung injury by IL-1 receptor blockade.
Thorax 2008;63(2):147-53.
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2008: Pittet Jean Francois; Song Yuanlin; Wiener-Kronish Jeanine P
Treating lung infections with anticoagulation: mechanisms matter.
Critical care medicine 2008;36(1):356-7.
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2007: Cohen Mitchell Jay; Brohi Karim; Ganter Michael T; Manley Geoffrey T; Mackersie Robert C; Pittet Jean-François
Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway.
The Journal of trauma 2007;63(6):1254-61; discussion 1261-2.
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2007: Ganter Michael T; Brohi Karim; Cohen Mitchell J; Shaffer Lisa A; Walsh Mary C; Stahl Gregory L; Pittet Jean-François
Role of the alternative pathway in the early complement activation following major trauma.
Shock (Augusta, Ga.) 2007;28(1):29-34.
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2007: Brohi Karim; Cohen Mitchell J; Ganter Michael T; Matthay Michael A; Mackersie Robert C; Pittet Jean-François
Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway?
Annals of surgery 2007;245(5):812-8.
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2007: Pespeni Melissa H; Hodnett Maki; Abayasiriwardana Keith S; Roux Jérémie; Howard Marybeth; Broaddus V Courtney; Pittet Jean-François
Sensitization of mesothelioma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by heat stress via the inhibition of the 3-phosphoinositide-dependent kinase 1/Akt pathway.
Cancer research 2007;67(6):2865-71.
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2007: Su George; Hodnett Maki; Wu Nanyan; Atakilit Amha; Kosinski Cynthia; Godzich Mika; Huang Xiao Zhu; Kim Jiyeun K; Frank James A; Matthay Michael A; Sheppard Dean; Pittet Jean-François
Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function.
American journal of respiratory cell and molecular biology 2007;36(3):377-86.
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2006: Guidot David M; Folkesson Hans G; Jain Lucky; Sznajder Jacob I; Pittet Jean-François; Matthay Michael A
Integrating acute lung injury and regulation of alveolar fluid clearance.
American journal of physiology. Lung cellular and molecular physiology 2006;291(3):L301-6.
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2006: Ganter Michael T; Ware Lorraine B; Howard Marybeth; Roux Jérémie; Gartland Brandi; Matthay Michael A; Fleshner Monika; Pittet Jean-François
Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury.
American journal of physiology. Lung cellular and molecular physiology 2006;291(3):L354-61.
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2006: Godzich M; Hodnett M; Frank J A; Su G; Pespeni M; Angel A; Howard M B; Matthay M A; Pittet J F
Activation of the stress protein response prevents the development of pulmonary edema by inhibiting VEGF cell signaling in a model of lung ischemia-reperfusion injury in rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(9):1519-21.
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2006: Tang Julin F; Pittet Jean-Francois; Ganter Michael T
Bring rapidly degradable hydroxyethyl starch to the United States.
Anesthesiology 2006;104(5):1105-6; author reply 1106.
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2006: Hashimoto Tomoki; Pittet Jean-Francois
Angiopoietin-2: modulator of vascular permeability in acute lung injury?
PLoS medicine 2006;3(3):e113.
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2006: Ganter Michael T; Pittet Jean-François
Bombesin-like peptides: modulators of inflammation in acute lung injury?
American journal of respiratory and critical care medicine 2006;173(1):1-2.
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2005: Pespeni Melissa; Mackersie Robert C; Lee Hyon; Morabito Diane; Hodnett Maki; Howard Marybeth; Pittet Jean-François
Serum levels of Hsp60 correlate with the development of acute lung injury after trauma.
The Journal of surgical research 2005;126(1):41-7.
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2005: Kallet Richard H; Jasmer Robert M; Pittet Jean-Francois; Tang Julin F; Campbell Andre R; Dicker Rochelle; Hemphill Claude; Luce John M
Clinical implementation of the ARDS network protocol is associated with reduced hospital mortality compared with historical controls.
Critical care medicine 2005;33(5):925-9.
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2005: Roux Jérémie; Kawakatsu Hisaaki; Gartland Brandi; Pespeni Melissa; Sheppard Dean; Matthay Michael A; Canessa Cecilia M; Pittet Jean-François
Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway.
The Journal of biological chemistry 2005;280(19):18579-89.
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2005: Pespeni Melissa; Hodnett Maki; Pittet Jean-Francois
In vivo stress preconditioning.
Methods (San Diego, Calif.) 2005;35(2):158-64.
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2005: Lee H; Pespeni M; Roux J; Dennery P A; Matthay M A; Pittet J F
HO-1 induction restores c-AMP-dependent lung epithelial fluid transport following severe hemorrhage in rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(2):287-9.
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2005: Pittet Jean-Francois; Lee Hyon; Pespeni Melissa; O'Mahony Allison; Roux Jeremie; Welch William J
Stress-induced inhibition of the NF-kappaB signaling pathway results from the insolubilization of the IkappaB kinase complex following its dissociation from heat shock protein 90.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):384-94.
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2004: Dicker Rochelle A; Morabito Diane J; Pittet Jean-Francois; Campbell Andre R; Mackersie Robert C
Acute respiratory distress syndrome criteria in trauma patients: why the definitions do not work.
The Journal of trauma 2004;57(3):522-6; discussion 526-8.
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2004: Kallet Richard H; Alonso James A; Pittet Jean-François; Matthay Michael A
Prognostic value of the pulmonary dead-space fraction during the first 6 days of acute respiratory distress syndrome.
Respiratory care 2004;49(9):1008-14.
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2004: Chiron B; Laffon M; Ferrandiere M; Pittet J F; Marret H; Mercier C
Standard preoxygenation technique versus two rapid techniques in pregnant patients.
International journal of obstetric anesthesia 2004;13(1):11-4.
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2003: Frank James; Roux Jérémie; Kawakatsu Hisaaki; Su George; Dagenais André; Berthiaume Yves; Howard Marybeth; Canessa Cecilia M; Fang Xiaohui; Sheppard Dean; Matthay Michael A; Pittet Jean-François
Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism.
The Journal of biological chemistry 2003;278(45):43939-50.
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2003: Chiron Bruno; Laffon Marc; Ferrandière Martine; Pittet Jean-François
Postdural puncture headache in a parturient with sickle cell disease: use of an epidural colloid patch.
Canadian journal of anaesthesia = Journal canadien d'anesthésie 2003;50(8):812-4.
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2003: Siobal Mark S; Kallet Richard H; Pittet Jean-François; Warnecke Edna L; Kraemer Roger W; Venkayya Rajeev V; Tang Julin F
Description and evaluation of a delivery system for aerosolized prostacyclin.
Respiratory care 2003;48(8):742-53.
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2003: Holland Martin C; Mackersie Robert C; Morabito Diane; Campbell Andre R; Kivett Valerie A; Patel Rajiv; Erickson Vanessa R; Pittet Jean-Francois
The development of acute lung injury is associated with worse neurologic outcome in patients with severe traumatic brain injury.
The Journal of trauma 2003;55(1):106-11.
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2003: Frank James A; Pittet Jean-Francois; Lee Hyon; Godzich Micaela; Matthay Michael A
High tidal volume ventilation induces NOS2 and impairs cAMP- dependent air space fluid clearance.
American journal of physiology. Lung cellular and molecular physiology 2003;284(5):L791-8.
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2002: Nuckton Thomas J; Alonso James A; Kallet Richard H; Daniel Brian M; Pittet Jean-François; Eisner Mark D; Matthay Michael A
Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome.
The New England journal of medicine 2002;346(17):1281-6.
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2002: Pittet Jean-François; Lee H; Morabito Diane; Howard M B; Welch William J; Mackersie Robert C
Serum levels of Hsp 72 measured early after trauma correlate with survival.
The Journal of trauma 2002;52(4):611-7; discussion 617.
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2002: Laffon Marc; Jayr Christian; Barbry Pascal; Wang Ybing; Folkesson Hans G; Pittet Jean-Francois; Clerici Christine; Matthay Michael A
Lidocaine induces a reversible decrease in alveolar epithelial fluid clearance in rats.
Anesthesiology 2002;96(2):392-9.
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2002: Pittet J F; Lu L N; Geiser T; Lee H; Matthay M A; Welch W J
Stress preconditioning attenuates oxidative injury to the alveolar epithelium of the lung following haemorrhage in rats.
The Journal of physiology 2002;538(Pt 2):583-97.
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2001: Pittet J F; Griffiths M J; Geiser T; Kaminski N; Dalton S L; Huang X; Brown L A; Gotwals P J; Koteliansky V E; Matthay M A; Sheppard D
TGF-beta is a critical mediator of acute lung injury.
The Journal of clinical investigation 2001;107(12):1537-44.
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2001: Pittet J F; Lu L N; Morris D G; Modelska K; Welch W J; Carey H V; Roux J; Matthay M A
Reactive nitrogen species inhibit alveolar epithelial fluid transport after hemorrhagic shock in rats.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6301-10.
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2000: Kallet R H; Katz J A; Pittet J F; Ghermey J; Siobal M; Alonso J A; Marks J D
Measuring intra-esophageal pressure to assess transmural pulmonary arterial occlusion pressure in patients with acute lung injury: a case series and review.
Respiratory care 2000;45(9):1072-84.
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2000: Guidot D M; Modelska K; Lois M; Jain L; Moss I M; Pittet J F; Brown L A
Ethanol ingestion via glutathione depletion impairs alveolar epithelial barrier function in rats.
American journal of physiology. Lung cellular and molecular physiology 2000;279(1):L127-35.
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2000: Kaminski N; Allard J D; Pittet J F; Zuo F; Griffiths M J; Morris D; Huang X; Sheppard D; Heller R A
Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1778-83.
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2000: Eberhard L W; Morabito D J; Matthay M A; Mackersie R C; Campbell A R; Marks J D; Alonso J A; Pittet J F
Initial severity of metabolic acidosis predicts the development of acute lung injury in severely traumatized patients.
Critical care medicine 2000;28(1):125-31.
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1999: Modelska K; Pittet J F; Folkesson H G; Courtney Broaddus V; Matthay M A
Acid-induced lung injury. Protective effect of anti-interleukin-8 pretreatment on alveolar epithelial barrier function in rabbits.
American journal of respiratory and critical care medicine 1999;160(5 Pt 1):1450-6.
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1999: Laffon M; Pittet J F; Modelska K; Matthay M A; Young D M
Interleukin-8 mediates injury from smoke inhalation to both the lung endothelial and the alveolar epithelial barriers in rabbits.
American journal of respiratory and critical care medicine 1999;160(5 Pt 1):1443-9.
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1999: Laffon M; Lu L N; Modelska K; Matthay M A; Pittet J F
alpha-adrenergic blockade restores normal fluid transport capacity of alveolar epithelium after hemorrhagic shock.
The American journal of physiology 1999;277(4 Pt 1):L760-8.
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1999: Miyazaki H; Broaddus V C; Wiener-Kronish J P; Sawa T; Pittet J F; Kravchenko V; Mathison J C; Nishizawa H; Hattori S; Yamakawa T; Yamada H; Kudoh I
The effects of two antiinflammatory pretreatments on bacterial-induced lung injury.
Anesthesiology 1999;90(6):1650-62.
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1999: Modelska K; Matthay M A; Brown L A; Deutch E; Lu L N; Pittet J F
Inhibition of beta-adrenergic-dependent alveolar epithelial clearance by oxidant mechanisms after hemorrhagic shock.
The American journal of physiology 1999;276(5 Pt 1):L844-57.
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1999: Munger J S; Huang X; Kawakatsu H; Griffiths M J; Dalton S L; Wu J; Pittet J F; Kaminski N; Garat C; Matthay M A; Rifkin D B; Sheppard D
The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis.
Cell 1999;96(3):319-28.
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1998: Cammarano W B; Pittet J F; Weitz S; Schlobohm R M; Marks J D
Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients.
Critical care medicine 1998;26(4):676-84.
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1998: Pittet J F; Kudoh I; Wiener-Kronish J P
Endothelial exposure to Pseudomonas aeruginosa proteases increases the vulnerability of the alveolar epithelium to a second injury.
American journal of respiratory cell and molecular biology 1998;18(1):129-35.
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1998: Matthay M A; Pittet J F; Jayr C
Just say NO to inhaled nitric oxide for the acute respiratory distress syndrome.
Critical care medicine 1998;26(1):1-2.
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1997: McElroy M C; Pittet J F; Allen L; Wiener-Kronish J P; Dobbs L G
Biochemical detection of type I cell damage after nitrogen dioxide-induced lung injury in rats.
The American journal of physiology 1997;273(6 Pt 1):L1228-34.
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1997: Modelska K; Matthay M A; McElroy M C; Pittet J F
Upregulation of alveolar liquid clearance after fluid resuscitation for hemorrhagic shock in rats.
The American journal of physiology 1997;273(2 Pt 1):L305-14.
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1997: McElroy M C; Wiener-Kronish J P; Miyazaki H; Sawa T; Modelska K; Dobbs L G; Pittet J F
Nitric oxide attenuates lung endothelial injury caused by sublethal hyperoxia in rats.
The American journal of physiology 1997;272(4 Pt 1):L631-8.
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1997: Pittet J F; Mackersie R C; Martin T R; Matthay M A
Biological markers of acute lung injury: prognostic and pathogenetic significance.
American journal of respiratory and critical care medicine 1997;155(4):1187-205.
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1996: Pittet J F; Brenner T J; Modelska K; Matthay M A
Alveolar liquid clearance is increased by endogenous catecholamines in hemorrhagic shock in rats.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;81(2):830-7.
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1996: Folkesson H G; Pittet J F; Nitenberg G; Matthay M A
Transforming growth factor-alpha increases alveolar liquid clearance in anesthetized ventilated rats.
The American journal of physiology 1996;271(2 Pt 1):L236-44.
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1996: Hashimoto S; Pittet J F; Hong K; Folkesson H; Bagby G; Kobzik L; Frevert C; Watanabe K; Tsurufuji S; Wiener-Kronish J
Depletion of alveolar macrophages decreases neutrophil chemotaxis to Pseudomonas airspace infections.
The American journal of physiology 1996;270(5 Pt 1):L819-28.
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1996: Sawa T; Miyazaki H; Pittet J F; Widdicombe J H; Gropper M A; Hashimoto S; Conrad D J; Folkesson H G; Debs R; Forsayeth J R; Fox B; Wiener-Kronish J P
Intraluminal water increases expression of plasmid DNA in rat lung.
Human gene therapy 1996;7(8):933-41.
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1996: Pittet J F; Hashimoto S; Pian M; McElroy M C; Nitenberg G; Wiener-Kronish J P
Exotoxin A stimulates fluid reabsorption from distal airspaces of lung in anesthetized rats.
The American journal of physiology 1996;270(2 Pt 1):L232-41.
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1995: Breuss J M; Gallo J; DeLisser H M; Klimanskaya I V; Folkesson H G; Pittet J F; Nishimura S L; Aldape K; Landers D V; Carpenter W
Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling.
Journal of cell science 1995;108 ( Pt 6)():2241-51.
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1995: Pittet J F; Wiener-Kronish J P; Serikov V; Matthay M A
Resistance of the alveolar epithelium to injury from septic shock in sheep.
American journal of respiratory and critical care medicine 1995;151(4):1093-100.
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1995: McElroy M C; Pittet J F; Hashimoto S; Allen L; Wiener-Kronish J P; Dobbs L G
A type I cell-specific protein is a biochemical marker of epithelial injury in a rat model of pneumonia.
The American journal of physiology 1995;268(2 Pt 1):L181-6.
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1995: Kudoh I; Ohtake M; Nishizawa H; Kurahashi K; Hattori S; Okumura F; Pittet J F; Wiener-Kronish J
The effect of pentoxifylline on acid-induced alveolar epithelial injury.
Anesthesiology 1995;82(2):531-41.
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1994: Kudoh I; Wiener-Kronish J P; Hashimoto S; Pittet J F; Frank D
Exoproduct secretions of Pseudomonas aeruginosa strains influence severity of alveolar epithelial injury.
The American journal of physiology 1994;267(5 Pt 1):L551-6.
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1994: Pittet J F; Wiener-Kronish J P; McElroy M C; Folkesson H G; Matthay M A
Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats.
The Journal of clinical investigation 1994;94(2):663-71.
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1994: Jayr C; Garat C; Meignan M; Pittet J F; Zelter M; Matthay M A
Alveolar liquid and protein clearance in anesthetized ventilated rats.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;76(6):2636-42.
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1994: Massion P P; Inoue H; Richman-Eisenstat J; Grunberger D; Jorens P G; Housset B; Pittet J F; Wiener-Kronish J P; Nadel J A
Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro.
The Journal of clinical investigation 1994;93(1):26-32.
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1993: Wiener-Kronish J P; Sakuma T; Kudoh I; Pittet J F; Frank D; Dobbs L; Vasil M L; Matthay M A
Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(4):1661-9.
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1993: Pittet J F; Matthay M A; Pier G; Grady M; Wiener-Kronish J P
Pseudomonas aeruginosa-induced lung and pleural injury in sheep. Differential protective effect of circulating versus alveolar immunoglobulin G antibody.
The Journal of clinical investigation 1993;92(3):1221-8.
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1993: Sakuma T; Pittet J F; Jayr C; Matthay M A
Alveolar liquid and protein clearance in the absence of blood flow or ventilation in sheep.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(1):176-85.
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1992: Espiritu R F; Pittet J F; Matthay M A; Goetzl E J
Neuropeptides in pulmonary edema fluid of adult respiratory distress syndrome.
Inflammation 1992;16(5):509-17.
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1991: Smedira N; Gates L; Hastings R; Jayr C; Sakuma T; Pittet J F; Matthay M A
Alveolar and lung liquid clearance in anesthetized rabbits.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;70(4):1827-35.
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