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Mikaël Pittet

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Chemicals & Drugs

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Melanoma

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Virna Cortez-Retamozo; Martin Etzrodt; Jose-Luiz Figueiredo; Reza Forghani; Rostic Gorbatov; Yoshiko Iwamoto; Rainer Kohler; Wilson Kuswanto; Brett Marinelli; Mari Mino-Kenudson; Matthias Nahrendorf; Andita Newton; Peter Panizzi; Ferdinando Pucci; Philipp J Rauch; Russell Ryan; Selena W Sio; Filip K Swirski; Ralph Weissleder; Gregory Wojtkiewicz; Ramnik Xavier; John W Chen; Aleksey Chudnovskiy; Mikaël J Pittet
Angiotensin II drives the production of tumor-promoting macrophages.
Martin Etzrodt; Frederic Geissmann; Etienne Meylan; Matthias Nahrendorf; Andita Newton; Aylwin Ng; Pedro Romero; Filip K Swirski; Ralph Weissleder; Moritz Wildgruber; Thomas Wurdinger; Ramnik Xavier; Jimmy Zhao; David Baltimore; Virna Cortez-Retamozo; Mikaël J Pittet
Regulation of monocyte functional heterogeneity by miR-146a and Relb.
Virna Cortez-Retamozo; Martin Etzrodt; Jose-Luiz Figueiredo; Reza Forghani; Rostic Gorbatov; Yoshiko Iwamoto; Victor Koteliansky; Brett Marinelli; Matthias Nahrendorf; Andita Newton; Tatiana I Novobrantseva; Daniel G Anderson; Cedric Berger; John W Chen; Aleksey Chudnovskiy; Philipp J Rauch; Russell J H Ryan; Filip K Swirski; Ralph Weissleder; Mikaël J Pittet
Origins of tumor-associated macrophages and neutrophils.

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All Publications

2013: Virna Cortez-Retamozo; Martin Etzrodt; Jose-Luiz Figueiredo; Reza Forghani; Rostic Gorbatov; Yoshiko Iwamoto; Rainer Kohler; Wilson Kuswanto; Brett Marinelli; Mari Mino-Kenudson; Matthias Nahrendorf; Andita Newton; Peter Panizzi; Ferdinando Pucci; Philipp J Rauch; Russell Ryan; Selena W Sio; Filip K Swirski; Ralph Weissleder; Gregory Wojtkiewicz; Ramnik Xavier; John W Chen; Aleksey Chudnovskiy; Mikaël J Pittet
Angiotensin II drives the production of tumor-promoting macrophages.
Immunity 2013;38(2):296-308.
2012: Martin Etzrodt; Frederic Geissmann; Etienne Meylan; Matthias Nahrendorf; Andita Newton; Aylwin Ng; Pedro Romero; Filip K Swirski; Ralph Weissleder; Moritz Wildgruber; Thomas Wurdinger; Ramnik Xavier; Jimmy Zhao; David Baltimore; Virna Cortez-Retamozo; Mikaël J Pittet
Regulation of monocyte functional heterogeneity by miR-146a and Relb.
Cell reports 2012;1(4):317-24.
2012: Virna Cortez-Retamozo; Martin Etzrodt; Jose-Luiz Figueiredo; Reza Forghani; Rostic Gorbatov; Yoshiko Iwamoto; Victor Koteliansky; Brett Marinelli; Matthias Nahrendorf; Andita Newton; Tatiana I Novobrantseva; Daniel G Anderson; Cedric Berger; John W Chen; Aleksey Chudnovskiy; Philipp J Rauch; Russell J H Ryan; Filip K Swirski; Ralph Weissleder; Mikaël J Pittet
Origins of tumor-associated macrophages and neutrophils.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(7):2491-6.
2012: Philipp J Rauch; Clinton S Robbins; Igor Theurl; Elizabeth Tiglao; Michael T Waring; Georg F Weber; Ralph Weissleder; Adam T Chicoine; Aleksey Chudnovskiy; Martin Etzrodt; Jose-Luiz Figueiredo; Rostic Gorbatov; Ingo Hilgendorf; Yoshiko Iwamoto; Majd Mouded; Matthias Nahrendorf; Mikaël J Pittet; Filip K Swirski
Innate response activator B cells protect against microbial sepsis.
Science (New York, N.Y.) 2012;335(6068):597-601.
2012: Florian Leuschner; Peter Libby; Brett Marinelli; Michael A Moskowitz; Aleksey Chudnovskiy; Partha Dutta; Rostic Gorbatov; John M Higgins; Yoshiko Iwamoto; Edmund Keliher; Won Woo Lee; Peter Panizzi; Mikaël J Pittet; Philipp J Rauch; Clinton Robbins; Brena Sena; Filip K Swirski; Takuya Ueno; Ying Wei; Ralph Weissleder; Matthias Nahrendorf
Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis.
The Journal of experimental medicine 2012;209(1):123-37.
2012: Virna Cortez-Retamozo; Martin Etzrodt; Mikaël J Pittet
Regulation of macrophage and dendritic cell responses by their lineage precursors.
Journal of innate immunity 2012;4(5-6):411-23.
2011: Mikaël J Pittet; Filip K Swirski
Monocytes link atherosclerosis and cancer.
European journal of immunology 2011;41(9):2519-22.
2011: Matthias Nahrendorf; Edmund Keliher; Brett Marinelli; Florian Leuschner; Clinton S Robbins; Robert E Gerszten; Mikaël J Pittet; Filip K Swirski; Ralph Weissleder
Detection of macrophages in aortic aneurysms by nanoparticle positron emission tomography-computed tomography.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(4):750-7.
2011: Yin Xia; Virna Cortez-Retamozo; Vera Niederkofler; Rishard Salie; Shanzhuo Chen; Tarek A Samad; Charles C Hong; Silvia Arber; Jatin M Vyas; Ralph Weissleder; Mikaël J Pittet; Herbert Y Lin
Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(3):1369-76.
2011: David Issadore; Huilin Shao; Jaehoon Chung; Andita Newton; Mikaël J Pittet; Ralph Weissleder; Hakho Lee
Self-assembled magnetic filter for highly efficient immunomagnetic separation.
Lab on a chip 2011;11(1):147-51.
2010: Florian Leuschner; Peter Panizzi; Isabel Chico-Calero; Won Woo Lee; Takuya Ueno; Virna Cortez-Retamozo; Peter Waterman; Rostic Gorbatov; Brett Marinelli; Yoshiko Iwamoto; Aleksey Chudnovskiy; Jose-Luiz Figueiredo; David E Sosnovik; Mikaël J Pittet; Filip K Swirski; Ralph Weissleder; Matthias Nahrendorf
Angiotensin-converting enzyme inhibition prevents the release of monocytes from their splenic reservoir in mice with myocardial infarction.
Circulation research 2010;107(11):1364-73.
2010: Matthias Nahrendorf; Edmund Keliher; Brett Marinelli; Peter Waterman; Paolo Fumene Feruglio; Lioubov Fexon; Misha Pivovarov; Filip K Swirski; Mikaël J Pittet; Claudio Vinegoni; Ralph Weissleder
Hybrid PET-optical imaging using targeted probes.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(17):7910-5.
2009: Matthias Nahrendorf; Peter Waterman; Greg Thurber; Kevin Groves; Milind Rajopadhye; Peter Panizzi; Brett Marinelli; Elena Aikawa; Mikaël J Pittet; Filip K Swirski; Ralph Weissleder
Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(10):1444-51.
2009: Filip K Swirski; Ralph Weissleder; Mikaël J Pittet
Heterogeneous in vivo behavior of monocyte subsets in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(10):1424-32.
2009: Filip K Swirski; Matthias Nahrendorf; Martin Etzrodt; Moritz Wildgruber; Virna Cortez-Retamozo; Peter Panizzi; Jose-Luiz Figueiredo; Rainer H Kohler; Aleksey Chudnovskiy; Peter Waterman; Elena Aikawa; Thorsten R Mempel; Peter Libby; Ralph Weissleder; Mikaël J Pittet
Identification of splenic reservoir monocytes and their deployment to inflammatory sites.
Science (New York, N.Y.) 2009;325(5940):612-6.
2009: Antoine Leimgruber; Cedric Berger; Virna Cortez-Retamozo; Martin Etzrodt; Andita P Newton; Peter Waterman; Jose-Luiz Figueiredo; Rainer H Kohler; Natalie Elpek; Thorsten R Mempel; Filip K Swirski; Matthias Nahrendorf; Ralph Weissleder; Mikaël J Pittet
Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle.
Neoplasia (New York, N.Y.) 2009;11(5):459-68, 2 p following 468.
2009: Moritz Wildgruber; Hakho Lee; Aleksey Chudnovskiy; Tae-Jong Yoon; Martin Etzrodt; Mikaël J Pittet; Matthias Nahrendorf; Kevin Croce; Peter Libby; Ralph Weissleder; Filip K Swirski
Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors.
PloS one 2009;4(5):e5663.
2008: Stanley Y Shaw; Elizabeth C Westly; Mikaël J Pittet; Aravind Subramanian; Stuart L Schreiber; Ralph Weissleder
Perturbational profiling of nanomaterial biologic activity.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(21):7387-92.
2008: Ralph Weissleder; Mikaël J Pittet
Imaging in the era of molecular oncology.
Nature 2008;452(7187):580-9.
2008: Fay C Magnusson; Roland S Liblau; Harald von Boehmer; Mikaël J Pittet; Je-Wook Lee; Shannon Turley; Khashayarsha Khazaie
Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.
Gastroenterology 2008;134(4):1028-37.
2008: Mikaël J Pittet; Thorsten R Mempel
Regulation of T-cell migration and effector functions: insights from in vivo imaging studies.
Immunological reviews 2008;221():107-29.
2007: Matthias Nahrendorf; Filip K Swirski; Elena Aikawa; Lars Stangenberg; Thomas Wurdinger; Jose-Luiz Figueiredo; Peter Libby; Ralph Weissleder; Mikaël J Pittet
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions.
The Journal of experimental medicine 2007;204(12):3037-47.
2007: Mikaël J Pittet; Jan Grimm; Cedric Berger; Takahiko Tamura; Gregory Wojtkiewicz; Matthias Nahrendorf; Pedro Romero; Filip K Swirski; Ralph Weissleder
In vivo imaging of T cell delivery to tumors after adoptive transfer therapy.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(30):12457-61.
2007: Jenny M Tam; Rabi Upadhyay; Mikaël J Pittet; Ralph Weissleder; Umar Mahmood
Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging.
Molecular imaging 2007;6(4):269-76.
2007: Matthias Nahrendorf; David E Sosnovik; Peter Waterman; Filip K Swirski; Ashvin N Pande; Elena Aikawa; Jose-Luiz Figueiredo; Mikaël J Pittet; Ralph Weissleder
Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct.
Circulation research 2007;100(8):1218-25.
2007: Pedro Romero; Alfred Zippelius; Isabel Kurth; Mikaël J Pittet; Cedric Touvrey; Emanuela M Iancu; Patricia Corthesy; Estelle Devevre; Daniel E Speiser; Nathalie Rufer
Four functionally distinct populations of human effector-memory CD8+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4112-9.
2007: Filip K Swirski; Cedric Berger; Jose-Luiz Figueiredo; Thorsten R Mempel; Ulrich H von Andrian; Mikaël J Pittet; Ralph Weissleder
A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses.
PloS one 2007;2(10):e1075.
2007: Filip K Swirski; Peter Libby; Elena Aikawa; Pilar Alcaide; Francis W Luscinskas; Ralph Weissleder; Mikaël J Pittet
Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata.
The Journal of clinical investigation 2007;117(1):195-205.
2006: Filip K Swirski; Mikaël J Pittet; Moritz Kircher; Elena Aikawa; Farouc A Jaffer; Peter Libby; Ralph Weissleder
Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10340-5.
2006: Thorsten R Mempel; Mikaël J Pittet; Khashayarsha Khazaie; Wolfgang Weninger; Ralph Weissleder; Harald von Boehmer; Ulrich H von Andrian
Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation.
Immunity 2006;25(1):129-41.
2006: Rachel Tréhin; Jose-Luiz Figueiredo; Mikaël J Pittet; Ralph Weissleder; Lee Josephson; Umar Mahmood
Fluorescent nanoparticle uptake for brain tumor visualization.
Neoplasia (New York, N.Y.) 2006;8(4):302-11.
2006: Mikaël J Pittet; Asma Gati; Frédérique-Anne Le Gal; Gilles Bioley; Philippe Guillaume; Magda De Smedt; Jean Plum; Daniel E Speiser; Jean-Charles Cerottini; Pierre-Yves Dietrich; Pedro Romero; Alfred Zippelius
Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2330-6.
2006: Mikaël J Pittet; Filip K Swirski; Frederick Reynolds; Lee Josephson; Ralph Weissleder
Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles.
Nature protocols 2006;1(1):73-9.
2005: M Montes; Nathalie Rufer; Victor Appay; Severine Reynard; Mikaël J Pittet; D E Speiser; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero; S Leyvraz
Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy.
Clinical and experimental immunology 2005;142(2):292-302.
2005: Mei-Ling Chen; Mikaël J Pittet; Leonid Gorelik; Richard A Flavell; Ralph Weissleder; Harald von Boehmer; Khashayarsha Khazaie
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):419-24.
2004: Norbert Meidenbauer; Alfred Zippelius; Mikaël J Pittet; Monika Laumer; Sandra Vogl; Jana Heymann; Michael Rehli; Barbara Seliger; Stephan Schwarz; Frédérique-Anne Le Gal; Pierre-Yves Dietrich; Reinhard Andreesen; Pedro Romero; Andreas Mackensen
High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma.
Cancer research 2004;64(17):6319-26.
2004: Daniel E Speiser; Mikaël J Pittet; Philippe Guillaume; Norbert Lubenow; Eric Hoffman; Jean-Charles Cerottini; Pedro Romero
Ex vivo analysis of human antigen-specific CD8+ T-cell responses: quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2004;27(4):298-308.
2004: Danielle Liénard; Donata Rimoldi; Marie Marchand; Pierre-Yves Dietrich; Nicolas van Baren; Christine Geldhof; Pascal Batard; Philippe Guillaume; Maha Ayyoub; Mikaël J Pittet; Alfred Zippelius; Katharina Fleischhauer; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero; Daniel E Speiser
Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA.
Cancer immunity 2004;4():4.
2004: Alfred Zippelius; Pascal Batard; Verena Rubio-Godoy; Gilles Bioley; Danielle Liénard; Ferdy Lejeune; Donata Rimoldi; Philippe Guillaume; Norbert Meidenbauer; Andreas Mackensen; Nathalie Rufer; Norbert Lubenow; Daniel Speiser; Jean-Charles Cerottini; Pedro Romero; Mikaël J Pittet
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.
Cancer research 2004;64(8):2865-73.
2004: Alfred Zippelius; Gilles Bioley; Frédérique-Anne Le Gal; Nathalie Rufer; Marlene Brandes; Pascal Batard; Magda De Smedt; Jean Plum; Daniel E Speiser; Jean-Charles Cerottini; Pierre-Yves Dietrich; Pedro Romero; Mikaël J Pittet
Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):2773-7.
2003: Daniel E Speiser; Mikaël J Pittet; Donata Rimoldi; Philippe Guillaume; Immanuel F Luescher; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells.
Seminars in cancer biology 2003;13(6):461-72.
2003: Nathalie Rufer; Alfred Zippelius; Pascal Batard; Mikaël J Pittet; Isabel Kurth; Patricia Corthesy; Jean-Charles Cerottini; Serge Leyvraz; Eddy Roosnek; Markus Nabholz; Pedro Romero
Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions.
Blood 2003;102(5):1779-87.
2003: Mikaël J Pittet; Verena Rubio-Godoy; Gilles Bioley; Philippe Guillaume; Pascal Batard; Daniel Speiser; Immanuel F Luescher; Jean-Charles Cerottini; Pedro Romero; Alfred Zippelius
Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):1844-9.
2003: Pierre-Yves Dietrich; Frédérique-Anne Le Gal; Valérie Dutoit; Mikaël J Pittet; Lydie Trautman; Alfred Zippelius; Isabelle Cognet; Valérie Widmer; Paul R Walker; Olivier Michielin; Philippe Guillaume; Thierry Connerotte; Francine Jotereau; Pierre G Coulie; Pedro Romero; Jean-Charles Cerottini; Marc Bonneville; Danila Valmori
Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):5103-9.
2003: Maha Ayyoub; Alfred Zippelius; Mikaël J Pittet; Donata Rimoldi; Danila Valmori; Jean-Charles Cerottini; Pedro Romero; Ferdy Lejeune; Danielle Liénard; Daniel E Speiser
Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):669-77.
2002: Pedro Romero; Danila Valmori; Mikaël J Pittet; Alfred Zippelius; Donata Rimoldi; Frédéric Lévy; Valérie Dutoit; Maha Ayyoub; Verena Rubio-Godoy; Olivier Michielin; Philippe Guillaume; Pascal Batard; Immanuel F Luescher; Ferdy Lejeune; Danielle Liénard; Nathalie Rufer; Pierre-Yves Dietrich; Daniel E Speiser; Jean-Charles Cerottini
Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma.
Immunological reviews 2002;188():81-96.
2002: Valérie Dutoit; Verena Rubio-Godoy; Mikaël J Pittet; Alfred Zippelius; Pierre-Yves Dietrich; Frédérique Anne Legal; Philippe Guillaume; Pedro Romero; Jean-Charles Cerottini; Richard A Houghten; Clemencia Pinilla; Danila Valmori
Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans.
The Journal of experimental medicine 2002;196(2):207-16.
2002: Mikaël J Pittet; Alfred Zippelius; Danila Valmori; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Melan-A/MART-1-specific CD8 T cells: from thymus to tumor.
Trends in immunology 2002;23(7):325-8.
2002: Danila Valmori; Valérie Dutoit; Valerie Schnuriger; Anne-Lise Quiquerez; Mikaël J Pittet; Philippe Guillaume; Verena Rubio-Godoy; Paul R Walker; Donata Rimoldi; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Pierre-Yves Dietrich
Vaccination with a Melan-A peptide selects an oligoclonal T cell population with increased functional avidity and tumor reactivity.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4231-40.
2002: Daniel E Speiser; Danielle Liénard; Mikaël J Pittet; Pascal Batard; Donata Rimoldi; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero
In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells.
European journal of immunology 2002;32(3):731-41.
2002: Tessa C C Kerre; Greet De Smet; Magda De Smedt; Alfred Zippelius; Mikaël J Pittet; Anton Langerak; José De Bosscher; Fritz Offner; Bart Vandekerckhove; Jean Plum
Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cells.
Blood 2002;99(5):1620-6.
2002: Alfred Zippelius; Mikaël J Pittet; Pascal Batard; Nathalie Rufer; Magda De Smedt; Philippe Guillaume; Kim Ellefsen; Danila Valmori; Danielle Liénard; Jean Plum; H Robson MacDonald; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Thymic selection generates a large T cell pool recognizing a self-peptide in humans.
The Journal of experimental medicine 2002;195(4):485-94.
2001: Daniel E Speiser; Marco COLONna; Maha Ayyoub; M Cella; Mikaël J Pittet; Pascal Batard; Danila Valmori; Philippe Guillaume; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero
The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6165-70.
2001: Mikaël J Pittet; Alfred Zippelius; Daniel E Speiser; M Assenmacher; Philippe Guillaume; Danila Valmori; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7634-40.
2001: Mikaël J Pittet; Daniel E Speiser; Danielle Liénard; Danila Valmori; Philippe Guillaume; Valérie Dutoit; Donata Rimoldi; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):796s-803s.
2001: Daniel E Speiser; M Migliaccio; Mikaël J Pittet; Danila Valmori; Danielle Liénard; F Lejeune; Patrick Reichenbach; Philippe Guillaume; I Lüscher; Jean-Charles Cerottini; Pedro Romero
Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells.
European journal of immunology 2001;31(2):459-66.
2000: Danila Valmori; Valérie Dutoit; Danielle Liénard; Donata Rimoldi; Mikaël J Pittet; Patrick Champagne; Kim Ellefsen; U Sahin; Daniel Speiser; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients.
Cancer research 2000;60(16):4499-506.
2000: Mikaël J Pittet; Daniel E Speiser; Danila Valmori; Jean-Charles Cerottini; Pedro Romero
Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1148-52.
1999: Daniel E Speiser; Mikaël J Pittet; Danila Valmori; R Dunbar; Donata Rimoldi; Danielle Liénard; H Robson MacDonald; Jean-Charles Cerottini; Vincenzo Cerundolo; Pedro Romero
In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes.
The Journal of experimental medicine 1999;190(6):775-82.
1999: Mikaël J Pittet; Danila Valmori; P R Dunbar; Daniel E Speiser; Danielle Liénard; Ferdy Lejeune; Katharina Fleischhauer; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.
The Journal of experimental medicine 1999;190(5):705-15.
1999: Danila Valmori; Mikaël J Pittet; C Vonarbourg; Donata Rimoldi; Danielle Liénard; Daniel Speiser; R Dunbar; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376.
Cancer research 1999;59(16):4050-5.
1999: Daniel E Speiser; Danila Valmori; Donata Rimoldi; Mikaël J Pittet; Danielle Liénard; Vincenzo Cerundolo; H Robson MacDonald; Jean-Charles Cerottini; Pedro Romero
CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients.
European journal of immunology 1999;29(6):1990-9.
1999: Danila Valmori; Mikaël J Pittet; Donata Rimoldi; Danielle Liénard; R Dunbar; Vincenzo Cerundolo; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
An antigen-targeted approach to adoptive transfer therapy of cancer.
Cancer research 1999;59(9):2167-73.
1998: Pedro Romero; P R Dunbar; Danila Valmori; Mikaël J Pittet; G S Ogg; Donata Rimoldi; J L Chen; Danielle Liénard; Jean-Charles Cerottini; Vincenzo Cerundolo
Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes.
The Journal of experimental medicine 1998;188(9):1641-50.