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Bryce Plapp

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Bryce V Plapp; Tea Lanisnik Rizner; Natalia Y Kedishvili; Edmund Maser; Peter J O'Brien
Chemico-Biological Interactions. Enzymology and molecular biology of carbonyl metabolism 16. Introduction.
Bryce V Plapp; Aditi Khanna; Ann Ting-I Lee; John M Pryor
Bradykinetic alcohol dehydrogenases make yeast fitter for growth in the presence of allyl alcohol.
Bryce V Plapp; S Ramaswamy
Atomic-resolution structures of horse liver alcohol dehydrogenase with NAD(+) and fluoroalcohols define strained Michaelis complexes.

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All Publications

2013: Bryce V Plapp; Tea Lanisnik Rizner; Natalia Y Kedishvili; Edmund Maser; Peter J O'Brien
Chemico-Biological Interactions. Enzymology and molecular biology of carbonyl metabolism 16. Introduction.
Chemico-biological interactions 2013;202(1-3):1.
2013: Bryce V Plapp; Aditi Khanna; Ann Ting-I Lee; John M Pryor
Bradykinetic alcohol dehydrogenases make yeast fitter for growth in the presence of allyl alcohol.
Chemico-biological interactions 2013;202(1-3):104-10.
2012: Bryce V Plapp; S Ramaswamy
Atomic-resolution structures of horse liver alcohol dehydrogenase with NAD(+) and fluoroalcohols define strained Michaelis complexes.
Biochemistry 2012;51(19):4035-48.
2011: T Geoffrey Flynn; Natalia Kedishvili; Edmund Maser; Peter J O'Brien; Bryce V Plapp
Enzymology and Molecular Biology of Carbonyl Metabolism, 15th International Meeting on Enzymology and Molecular Biology of Carbonyl Metabolism. Introduction.
Chemico-biological interactions 2011;191(1-3):1.
2011: Timothy John Herdendorf; Bryce V Plapp
Origins of the high catalytic activity of human alcohol dehydrogenase 4 studied with horse liver A317C alcohol dehydrogenase.
Chemico-biological interactions 2011;191(1-3):42-7.
2010: Bryce V Plapp
Conformational changes and catalysis by alcohol dehydrogenase.
Archives of biochemistry and biophysics 2010;493(1):3-12.
2009: Suresh Pal; Doo-Hong Park; Bryce V Plapp
Activity of yeast alcohol dehydrogenases on benzyl alcohols and benzaldehydes: characterization of ADH1 from Saccharomyces carlsbergensis and transition state analysis.
Chemico-biological interactions 2009;178(1-3):16-23.
2005: Xixuan H Collins; Shawn D Harmon; Terry L Kaduce; Kristine B Berst; Xiang Fang; Steven A Moore; T Verugopal Raju; John R Falck; Neal L Weintraub; Gregg Duester; Bryce V Plapp; Arthur A Spector
Omega-oxidation of 20-hydroxyeicosatetraenoic acid (20-HETE) in cerebral microvascular smooth muscle and endothelium by alcohol dehydrogenase 4.
The Journal of biological chemistry 2005;280(39):33157-64.
2005: Elena G Kovaleva; Bryce V Plapp
Deprotonation of the horse liver alcohol dehydrogenase-NAD+ complex controls formation of the ternary complexes.
Biochemistry 2005;44(38):12797-808.
2004: Laurie A LeBrun; Doo-Hong Park; S Ramaswamy; Bryce V Plapp
Participation of histidine-51 in catalysis by horse liver alcohol dehydrogenase.
Biochemistry 2004;43(11):3014-26.
2004: Patrik Strömberg; Stefan Svensson; Kristine B Berst; Bryce V Plapp; Jan-Olov Höög
Enzymatic mechanism of low-activity mouse alcohol dehydrogenase 2.
Biochemistry 2004;43(5):1323-8.
2003: Hirekodathakallu Thulasiram; Bryce V Plapp
Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism.
The Journal of biological chemistry 2003;278(38):36699-706.
2003: Jon K Rubach; Bryce V Plapp
Amino acid residues in the nicotinamide binding site contribute to catalysis by horse liver alcohol dehydrogenase.
Biochemistry 2003;42(10):2907-15.
2003: Bryce V Plapp; Kristine B Berst
Specificity of human alcohol dehydrogenase 1C*2 (gamma2gamma2) for steroids and simulation of the uncompetitive inhibition of ethanol metabolism.
Chemico-biological interactions 2003;143-144():183-93.
2002: Jon K Rubach; Bryce V Plapp
Mobility of fluorobenzyl alcohols bound to liver alcohol dehydrogenases as determined by NMR and X-ray crystallographic studies.
Biochemistry 2002;41(52):15770-9.
2001: Jon K Rubach; S Ramaswamy; Bryce V Plapp
Contributions of valine-292 in the nicotinamide binding site of liver alcohol dehydrogenase and dynamics to catalysis.
Biochemistry 2001;40(42):12686-94.
2001: Bryce V Plapp; Jennifer L Mitchell; Kristine B Berst
Mouse alcohol dehydrogenase 4: kinetic mechanism, substrate specificity and simulation of effects of ethanol on retinoid metabolism.
Chemico-biological interactions 2001;130-132(1-3):445-56.
2000: H A Charlier; Bryce V Plapp
Kinetic cooperativity of human liver alcohol dehydrogenase gamma(2).
The Journal of biological chemistry 2000;275(16):11569-75.
1999: S Ramaswamy; Doo-Hong Park; Bryce V Plapp
Substitutions in a flexible loop of horse liver alcohol dehydrogenase hinder the conformational change and unmask hydrogen transfer.
Biochemistry 1999;38(42):13951-9.
1999: Laurie A LeBrun; Bryce V Plapp
Control of coenzyme binding to horse liver alcohol dehydrogenase.
Biochemistry 1999;38(38):12387-93.
1999: Gregg Duester; Jaume Farrés; Michael R Felder; R S Holmes; Jan-Olov Höög; Xavier Parés; Bryce V Plapp; Shih-Jiun Yin; H Jörnvall
Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family.
Biochemical pharmacology 1999;58(3):389-95.
1999: F Fan; Bryce V Plapp
Probing the affinity and specificity of yeast alcohol dehydrogenase I for coenzymes.
Archives of biochemistry and biophysics 1999;367(2):240-9.
1999: Bryce V Plapp; V K Chadha; Kevin Leidal; H Cho; M Scholze; JF Schindler; Kristine B Berst; S Ramaswamy
Uncompetitive inhibitors of alcohol dehydrogenases.
Advances in experimental medicine and biology 1999;463():295-303.
1998: F Strasser; J Dey; M R Eftink; Bryce V Plapp
Activation of horse liver alcohol dehydrogenase upon substitution of tryptophan 314 at the dimer interface.
Archives of biochemistry and biophysics 1998;358(2):369-76.
1998: Hong Deng; JF Schindler; Kristine B Berst; Bryce V Plapp; Robert Callender
A Raman spectroscopic characterization of bonding in the complex of horse liver alcohol dehydrogenase with NADH and N-cyclohexylformamide.
Biochemistry 1998;37(40):14267-78.
1998: JF Schindler; Kristine B Berst; Bryce V Plapp
Inhibition of human alcohol dehydrogenases by formamides.
Journal of medicinal chemistry 1998;41(10):1696-701.
1998: H Cho; Bryce V Plapp
Specificity of alcohol dehydrogenases for sulfoxides.
Biochemistry 1998;37(13):4482-9.
1997: S Ramaswamy; M Scholze; Bryce V Plapp
Binding of formamides to liver alcohol dehydrogenase.
Biochemistry 1997;36(12):3522-7.
1997: H Cho; S Ramaswamy; Bryce V Plapp
Flexibility of liver alcohol dehydrogenase in stereoselective binding of 3-butylthiolane 1-oxides.
Biochemistry 1997;36(2):382-9.
1997: F Strasser; M N Huyng; Bryce V Plapp
Activity of liver alcohol dehydrogenases on steroids.
Advances in experimental medicine and biology 1997;414():313-20.
1995: F Fan; Bryce V Plapp
Substitutions of isoleucine residues at the adenine binding site activate horse liver alcohol dehydrogenase.
Biochemistry 1995;34(14):4709-13.
1994: S Ramaswamy; Hans Eklund; Bryce V Plapp
Structures of horse liver alcohol dehydrogenase complexed with NAD+ and substituted benzyl alcohols.
Biochemistry 1994;33(17):5230-7.
1994: S Ramaswamy; D A Kratzer; A D Hershey; Paul H Rogers; Arthur Arnone; Hans Eklund; Bryce V Plapp
Crystallization and preliminary crystallographic studies of Saccharomyces cerevisiae alcohol dehydrogenase I.
Journal of molecular biology 1994;235(2):777-9.
1994: Bryce V Plapp
Control of alcohol metabolism.
EXS 1994;71():311-22.
1994: Hans Eklund; S Ramaswamy; Bryce V Plapp; Mustapha El-Ahmad; O Danielsson; Jan-Olov Höög; Hans Jörnvall
Crystallographic investigations of alcohol dehydrogenases.
EXS 1994;71():269-77.
1993: G L Shearer; K Kim; K M Lee; C K Wang; Bryce V Plapp
Alternative pathways and reactions of benzyl alcohol and benzaldehyde with horse liver alcohol dehydrogenase.
Biochemistry 1993;32(41):11186-94.
1993: David Green; Hong-Wei Sun; Bryce V Plapp
Inversion of the substrate specificity of yeast alcohol dehydrogenase.
The Journal of biological chemistry 1993;268(11):7792-8.
1993: Bryce V Plapp; David Green; Hong-Wei Sun; D H Park; K Kim
Substrate specificity of alcohol dehydrogenases.
Advances in experimental medicine and biology 1993;328():391-400.
1992: D R Light; M S Dennis; I J Forsythe; C C Liu; David Green; D A Kratzer; Bryce V Plapp
Alpha-isoenzyme of alcohol dehydrogenase from monkey liver. Cloning, expression, mechanism, coenzyme, and substrate specificity.
The Journal of biological chemistry 1992;267(18):12592-9.
1992: Hong-Wei Sun; Bryce V Plapp
Progressive sequence alignment and molecular evolution of the Zn-containing alcohol dehydrogenase family.
Journal of molecular evolution 1992;34(6):522-35.
1992: D H Park; Bryce V Plapp
Interconversion of E and S isoenzymes of horse liver alcohol dehydrogenase. Several residues contribute indirectly to catalysis.
The Journal of biological chemistry 1992;267(8):5527-33.
1991: D H Park; Bryce V Plapp
Isoenzymes of horse liver alcohol dehydrogenase active on ethanol and steroids. cDNA cloning, expression, and comparison of active sites.
The Journal of biological chemistry 1991;266(20):13296-302.
1991: F Fan; J A Lorenzen; Bryce V Plapp
An aspartate residue in yeast alcohol dehydrogenase I determines the specificity for coenzyme.
Biochemistry 1991;30(26):6397-401.
1991: Bryce V Plapp; A J Ganzhorn; R M Gould; David Green; T Jacobi; E Warth; D A Kratzer
Catalysis by yeast alcohol dehydrogenase.
Advances in experimental medicine and biology 1991;284():241-51.
1990: R M Gould; Bryce V Plapp
Substitution of arginine for histidine-47 in the coenzyme binding site of yeast alcohol dehydrogenase I.
Biochemistry 1990;29(23):5463-8.
1990: V C Sekhar; Bryce V Plapp
Rate constants for a mechanism including intermediates in the interconversion of ternary complexes by horse liver alcohol dehydrogenase.
Biochemistry 1990;29(18):4289-95.
1988: V C Sekhar; Bryce V Plapp
Mechanism of binding of horse liver alcohol dehydrogenase and nicotinamide adenine dinucleotide.
Biochemistry 1988;27(14):5082-8.
1988: K M Lee; K F Dahlhauser; Bryce V Plapp
Reactivity of horse liver alcohol dehydrogenase with 3-methylcyclohexanols.
Biochemistry 1988;27(9):3528-32.
1988: A J Ganzhorn; Bryce V Plapp
Carboxyl groups near the active site zinc contribute to catalysis in yeast alcohol dehydrogenase.
The Journal of biological chemistry 1988;263(11):5446-54.
1987: A J Ganzhorn; David Green; Alfred D Hershey; R M Gould; Bryce V Plapp
Kinetic characterization of yeast alcohol dehydrogenases. Amino acid residue 294 and substrate specificity.
The Journal of biological chemistry 1987;262(8):3754-61.
1987: Bryce V Plapp; M Parsons; Kevin Leidal; B A Baggenstoss; J R Ferm; S S Wear
Characterization of alcohol dehydrogenase from cultured rat hepatoma (HTC) cells.
Progress in clinical and biological research 1987;232():203-15.
1987: Bryce V Plapp; A J Ganzhorn; R M Gould; David Green; Alfred D Hershey
Structure and function in yeast alcohol dehydrogenases.
Progress in clinical and biological research 1987;232():227-36.
1986: Bryce V Plapp; D C Sogin; R T Dworschack; D P Bohlken; C Woenckhaus; R Jeck
Kinetics of native and modified liver alcohol dehydrogenase with coenzyme analogues: isomerization of enzyme-nicotinamide adenine dinucleotide complex.
Biochemistry 1986;25(19):5396-402.
1985: V K Chadha; Kevin Leidal; Bryce V Plapp
Inhibition of liver alcohol dehydrogenase and ethanol metabolism by 3-substituted thiolane 1-oxides.
Journal of medicinal chemistry 1985;28(1):36-40.
1984: Bryce V Plapp; Kevin Leidal; R K Smith; B P Murch
Kinetics of inhibition of ethanol metabolism in rats and the rate-limiting role of alcohol dehydrogenase.
Archives of biochemistry and biophysics 1984;230(1):30-8.
1984: V K Chadha; Bryce V Plapp
Inactivation of horse liver alcohol dehydrogenase by modification of cysteine residue 174 with 3-bromopropionic acid.
Biochemistry 1984;23(2):216-21.
1983: R W Fries; D P Bohlken; B P Murch; Kevin Leidal; Bryce V Plapp
omega-haloalkyl esters of 5'-adenosine monophosphate as potential active-site-directed reagents for dehydrogenases.
Archives of biochemistry and biophysics 1983;225(1):110-5.
1983: V K Chadha; Kevin Leidal; Bryce V Plapp
Inhibition by carboxamides and sulfoxides of liver alcohol dehydrogenase and ethanol metabolism.
Journal of medicinal chemistry 1983;26(6):916-22.
1981: P H Mundill; R W Fries; C Woenckhaus; Bryce V Plapp
Sulfonate analogues of adenosine nucleotides as inhibitors of nucleotide-binding enzymes.
Journal of medicinal chemistry 1981;24(4):474-7.
1981: W S Chen; D P Bohlken; Bryce V Plapp
Inactivation of liver alcohol dehydrogenases and inhibition of ethanol metabolism by ambivalent active-site-directed reagents.
Journal of medicinal chemistry 1981;24(2):190-3.
1980: W S Chen; D P Bohlken; Bryce V Plapp
In vivo evaluation of ambivalent active-site-directed inactivators of liver alcohol dehydrogenase.
Advances in experimental medicine and biology 1980;132():129-35.