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Leonidas Platanias

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Unno Kenji; Zhou Ying; Zimmerman Todd; Platanias Leonidas C; Wickrema Amittha
Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma.
Eklund Elizabeth A; Platanias Leonidas C
Screening for microRNAs in myelodysplastic syndromes.
Kroczynska Barbara; Kaur Surinder; Platanias Leonidas C
Growth suppressive cytokines and the AKT/mTOR pathway.

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All Publications

2009: Unno Kenji; Zhou Ying; Zimmerman Todd; Platanias Leonidas C; Wickrema Amittha
Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma.
Leukemia & lymphoma 2009;50(11):1865-71.
2009: Eklund Elizabeth A; Platanias Leonidas C
Screening for microRNAs in myelodysplastic syndromes.
Leukemia & lymphoma 2009;50(11):1735-6.
2009: Kroczynska Barbara; Kaur Surinder; Platanias Leonidas C
Growth suppressive cytokines and the AKT/mTOR pathway.
Cytokine 2009;48(1-2):138-43.
2009: Katsoulidis Efstratios; Carayol Nathalie; Woodard Jennifer; Konieczna Iwona; Majchrzak-Kita Beata; Jordan Alison; Sassano Antonella; Eklund Elizabeth A; Fish Eleanor N; Platanias Leonidas C
Role of Schlafen 2 (SLFN2) in the generation of interferon alpha-induced growth inhibitory responses.
The Journal of biological chemistry 2009;284(37):25051-64.
2009: Joshi Sonali; Kaur Surinder; Redig Amanda J; Goldsborough Katy; David Kevin; Ueda Takeshi; Watanabe-Fukunaga Rie; Baker Darren P; Fish Eleanor N; Fukunaga Rikiro; Platanias Leonidas C
Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(29):12097-102.
2009: Hussain Azhar R; Ahmed Maqbool; Ahmed Saeeda O; Al-Thari Sara; Khan Asma S; Razack Shirin; Platanias Leonidas C; Al-Kuraya Khawla S; Uddin Shahab
Proteasome inhibitor MG-132 mediated expression of p27Kip1 via S-phase kinase protein 2 degradation induces cell cycle coupled apoptosis in primary effusion lymphoma cells.
Leukemia & lymphoma 2009;50(7):1204-13.
2009: Platanias Leonidas C
Biological responses to arsenic compounds.
The Journal of biological chemistry 2009;284(28):18583-7.
2009: Kroczynska Barbara; Kaur Surinder; Katsoulidis Efstratios; Majchrzak-Kita Beata; Sassano Antonella; Kozma Sara C; Fish Eleanor N; Platanias Leonidas C
Interferon-dependent engagement of eukaryotic initiation factor 4B via S6 kinase (S6K)- and ribosomal protein S6K-mediated signals.
Molecular and cellular biology 2009;29(10):2865-75.
2009: Altman Jessica K; Platanias Leonidas C
Prospects for mTOR targeting in adult T cell leukemia.
Leukemia & lymphoma 2009;50(4):525-6.
2009: Redig Amanda J; Sassano Antonella; Majchrzak-Kita Beata; Katsoulidis Efstratios; Liu Hui; Altman Jessica K; Fish Eleanor N; Wickrema Amittha; Platanias Leonidas C
Activation of protein kinase C{eta} by type I interferons.
The Journal of biological chemistry 2009;284(16):10301-14.
2009: Sassano Antonella; Lo Iacono Marco; Antico Giovanni; Jordan Alison; Uddin Shahab; Calogero Raffaele A; Platanias Leonidas C
Regulation of leukemic cell differentiation and retinoid-induced gene expression by statins.
Molecular cancer therapeutics 2009;8(3):615-25.
2009: Minhajuddin Mohd; Bijli Kaiser M; Fazal Fabeha; Sassano Antonella; Nakayama Keiichi I; Hay Nissim; Platanias Leonidas C; Rahman Arshad
Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells.
The Journal of biological chemistry 2009;284(7):4052-61.
2008: Kaur Surinder; Sassano Antonella; Joseph Ajith M; Majchrzak-Kita Beata; Eklund Elizabeth A; Verma Amit; Brachmann Saskia M; Fish Eleanor N; Platanias Leonidas C
Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):7316-23.
2008: Navas Tony; Zhou Li; Estes Myka; Haghnazari Edwin; Nguyen Aaron N; Mo Yongkai; Pahanish Perry; Mohindru Mani; Cao Tim; Higgins Linda S; Platanias Leonidas C; List Alan; Verma Amit
Inhibition of p38alpha MAPK disrupts the pathological loop of proinflammatory factor production in the myelodysplastic syndrome bone marrow microenvironment.
Leukemia & lymphoma 2008;49(10):1963-75.
2008: Hussain Azhar R; Ahmed Maqbool; Al-Jomah Naif A; Khan Asma S; Manogaran Pulicat; Sultana Mehar; Abubaker Jehad; Platanias Leonidas C; Al-Kuraya Khawla S; Uddin Shahab
Curcumin suppresses constitutive activation of nuclear factor-kappa B and requires functional Bax to induce apoptosis in Burkitt's lymphoma cell lines.
Molecular cancer therapeutics 2008;7(10):3318-29.
2008: Zhou Li; Nguyen Aaron N; Sohal Davendra; Ying Ma Jing; Pahanish Perry; Gundabolu Krishna; Hayman Josh; Chubak Adam; Mo Yongkai; Bhagat Tushar D; Das Bhaskar; Kapoun Ann M; Navas Tony A; Parmar Simrit; Kambhampati Suman; Pellagatti Andrea; Braunchweig Ira; Zhang Ying; Wickrema Amittha; Medicherla Satyanarayana; Boultwood Jacqueline; Platanias Leonidas C; Higgins Linda S; List Alan F; Bitzer Markus; Verma Amit
Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.
Blood 2008;112(8):3434-43.
2008: Kaur Surinder; Katsoulidis Efstratios; Platanias Leonidas C
Akt and mRNA translation by interferons.
Cell cycle (Georgetown, Tex.) 2008;7(14):2112-6.
2008: Woodard Jennifer; Sassano Antonella; Hay Nissim; Platanias Leonidas C
Statin-dependent suppression of the Akt/mammalian target of rapamycin signaling cascade and programmed cell death 4 up-regulation in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(14):4640-9.
2008: Redig Amanda J; Platanias Leonidas C
Protein kinase C signalling in leukemia.
Leukemia & lymphoma 2008;49(7):1255-62.
2008: Uddin Shahab; Platanias Leonidas C
Sphingosine kinase is an attractive target for novel pharmacological interventions in non-Hodgkin lymphomas.
Leukemia & lymphoma 2008;49(5):850-1.
2008: Murooka Thomas T; Rahbar Ramtin; Platanias Leonidas C; Fish Eleanor N
CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1.
Blood 2008;111(10):4892-901.
2008: Dolniak Blazej; Katsoulidis Efstratios; Carayol Nathalie; Altman Jessica K; Redig Amanda J; Tallman Martin S; Ueda Takeshi; Watanabe-Fukunaga Rie; Fukunaga Rikiro; Platanias Leonidas C
Regulation of arsenic trioxide-induced cellular responses by Mnk1 and Mnk2.
The Journal of biological chemistry 2008;283(18):12034-42.
2008: Katsoulidis Efstratios; Sassano Antonella; Majchrzak-Kita Beata; Carayol Nathalie; Yoon Patrick; Jordan Alison; Druker Brian J; Fish Eleanor N; Platanias Leonidas C
Suppression of interferon (IFN)-inducible genes and IFN-mediated functional responses in BCR-ABL-expressing cells.
The Journal of biological chemistry 2008;283(16):10793-803.
2008: Kannan-Thulasiraman Padma; Dolniak Blazej; Kaur Surinder; Sassano Antonella; Kalvakolanu Dhananjaya V; Hay Nissim; Platanias Leonidas C
Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids.
Biochemical and biophysical research communications 2008;368(4):983-9.
2008: Kaur Surinder; Sassano Antonella; Dolniak Blazej; Joshi Sonali; Majchrzak-Kita Beata; Baker Darren P; Hay Nissim; Fish Eleanor N; Platanias Leonidas C
Role of the Akt pathway in mRNA translation of interferon-stimulated genes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(12):4808-13.
2008: Altman Jessica K; Platanias Leonidas C
Exploiting the mammalian target of rapamycin pathway in hematologic malignancies.
Current opinion in hematology 2008;15(2):88-94.
2008: Konieczna Iwona; Horvath Elizabeth; Wang Hao; Lindsey Stephan; Saberwal Gurveen; Bei Ling; Huang Weiqi; Platanias Leonidas; Eklund Elizabeth A
Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia.
The Journal of clinical investigation 2008;118(3):853-67.
2008: Carayol Nathalie; Katsoulidis Efstratios; Sassano Antonella; Altman Jessica K; Druker Brian J; Platanias Leonidas C
Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway.
The Journal of biological chemistry 2008;283(13):8601-10.
2008: Sassano Antonella; Platanias Leonidas C
Statins in tumor suppression.
Cancer letters 2008;260(1-2):11-9.
2008: Altman Jessica K; Yoon Patrick; Katsoulidis Efstratios; Kroczynska Barbara; Sassano Antonella; Redig Amanda J; Glaser Heather; Jordan Alison; Tallman Martin S; Hay Nissim; Platanias Leonidas C
Regulatory effects of mammalian target of rapamycin-mediated signals in the generation of arsenic trioxide responses.
The Journal of biological chemistry 2008;283(4):1992-2001.
2007: Redig Amanda J; Platanias Leonidas C
The protein kinase C (PKC) family of proteins in cytokine signaling in hematopoiesis.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2007;27(8):623-36.
2007: Ma X; Kalakonda S; Srinivasula S M; Reddy S P; Platanias L C; Kalvakolanu D V
GRIM-19 associates with the serine protease HtrA2 for promoting cell death.
Oncogene 2007;26(33):4842-9.
2007: Sassano Antonella; Katsoulidis Efstratios; Antico Giovanni; Altman Jessica K; Redig Amanda J; Minucci Saverio; Tallman Martin S; Platanias Leonidas C
Suppressive effects of statins on acute promyelocytic leukemia cells.
Cancer research 2007;67(9):4524-32.
2007: Hussain Azhar R; Al-Jomah Naif A; Siraj Abdul K; Manogaran Pulicat; Al-Hussein Khalid; Abubaker Jehad; Platanias Leonidas C; Al-Kuraya Khawla S; Uddin Shahab
Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells.
Cancer research 2007;67(8):3888-97.
2007: Bijli Kaiser M; Minhajuddin Mohd; Fazal Fabeha; O'Reilly Michael A; Platanias Leonidas C; Rahman Arshad
c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells.
American journal of physiology. Lung cellular and molecular physiology 2007;292(2):L396-404.
2007: Kaur Surinder; Lal Lakhvir; Sassano Antonella; Majchrzak-Kita Beata; Srikanth Maya; Baker Darren P; Petroulakis Emmanuel; Hay Nissim; Sonenberg Nahum; Fish Eleanor N; Platanias Leonidas C
Regulatory effects of mammalian target of rapamycin-activated pathways in type I and II interferon signaling.
The Journal of biological chemistry 2007;282(3):1757-68.
2007: Layden Brian T; Joseph Mathew; Tallman Martin S; Platanias Leonidas C
Acute lymphoblastic leukemia in a patient with chronic cyanoacrylate exposure.
Acta haematologica 2007;118(4):242-3.
2006: Navas Tony A; Mohindru Mani; Estes Myka; Ma Jing Ying; Sokol Lubomir; Pahanish Perry; Parmar Simrit; Haghnazari Edwin; Zhou Li; Collins Robert; Kerr Irene; Nguyen Aaron N; Xu Yin; Platanias Leonidas C; List Alan A; Higgins Linda S; Verma Amit
Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors.
Blood 2006;108(13):4170-7.
2006: Yoon Patrick; Giafis Nick; Smith Jessica; Mears Heather; Katsoulidis Efstratios; Sassano Antonella; Altman Jessica; Redig Amanda J; Tallman Martin S; Platanias Leonidas C
Activation of mammalian target of rapamycin and the p70 S6 kinase by arsenic trioxide in BCR-ABL-expressing cells.
Molecular cancer therapeutics 2006;5(11):2815-23.
2006: Gidron Adi; Platanias Leonidas C
MTHFR polymorphisms and the development of acute leukemia: does it really matter?
Leukemia & lymphoma 2006;47(10):2002-3.
2006: Kannan-Thulasiraman Padma; Katsoulidis Efstratios; Tallman Martin S; Arthur J Simon C; Platanias Leonidas C
Activation of the mitogen- and stress-activated kinase 1 by arsenic trioxide.
The Journal of biological chemistry 2006;281(32):22446-52.
2006: Giafis Nick; Katsoulidis Efstratios; Sassano Antonella; Tallman Martin S; Higgins Linda S; Nebreda Angel R; Davis Roger J; Platanias Leonidas C
Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses.
Cancer research 2006;66(13):6763-71.
2006: Rahbar Ramtin; Murooka Thomas T; Hinek Anna A; Galligan Carole L; Sassano Antonella; Yu Celeste; Srivastava Kishore; Platanias Leonidas C; Fish Eleanor N
Vaccinia virus activation of CCR5 invokes tyrosine phosphorylation signaling events that support virus replication.
Journal of virology 2006;80(14):7245-59.
2006: Platanias Leonidas C
Vitamin D and acute promyelocytic leukemia.
Leukemia & lymphoma 2006;47(4):581.
2006: Hussain A R; Al-Rasheed M; Manogaran P S; Al-Hussein K A; Platanias L C; Al Kuraya K; Uddin S
Curcumin induces apoptosis via inhibition of PI3'-kinase/AKT pathway in acute T cell leukemias.
Apoptosis : an international journal on programmed cell death 2006;11(2):245-54.
2005: Kaur Surinder; Uddin Shahab; Platanias Leonidas C
The PI3' kinase pathway in interferon signaling.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2005;25(12):780-7.
2005: Katsoulidis Efstratios; Li Yongzhong; Mears Heather; Platanias Leonidas C
The p38 mitogen-activated protein kinase pathway in interferon signal transduction.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2005;25(12):749-56.
2005: Platanias Leonidas C
Introduction: interferon signals: what is classical and what is nonclassical?
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2005;25(12):732.
2005: Katsoulidis Efstratios; Li Yongzhong; Yoon Patrick; Sassano Antonella; Altman Jessica; Kannan-Thulasiraman Padma; Balasubramanian Lakshmi; Parmar Simrit; Varga John; Tallman Martin S; Verma Amit; Platanias Leonidas C
Role of the p38 mitogen-activated protein kinase pathway in cytokine-mediated hematopoietic suppression in myelodysplastic syndromes.
Cancer research 2005;65(19):9029-37.
2005: Uddin Shahab; Hussain Azhar R; Manogaran Pulicat S; Al-Hussein Khaled; Platanias Leonidas C; Gutierrez Marina I; Bhatia Kishor G
Curcumin suppresses growth and induces apoptosis in primary effusion lymphoma.
Oncogene 2005;24(47):7022-30.
2005: Parmar Simrit; Smith Jessica; Sassano Antonella; Uddin Shahab; Katsoulidis Efstratios; Majchrzak Beata; Kambhampati Suman; Eklund Elizabeth A; Tallman Martin S; Fish Eleanor N; Platanias Leonidas C
Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells.
Blood 2005;106(7):2436-43.
2005: Roy Sanjit K; Shuman Jon D; Platanias Leonidas C; Shapiro Paul S; Reddy Sekhar P M; Johnson Peter F; Kalvakolanu Dhananjaya V
A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{beta}-dependent gene expression in response to interferon-{gamma}.
The Journal of biological chemistry 2005;280(26):24462-71.
2005: Emerling Brooke M; Platanias Leonidas C; Black Emma; Nebreda Angel R; Davis Roger J; Chandel Navdeep S
Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling.
Molecular and cellular biology 2005;25(12):4853-62.
2005: Platanias Leonidas C
Mechanisms of type-I- and type-II-interferon-mediated signalling.
Nature reviews. Immunology 2005;5(5):375-86.
2005: Kaur Surinder; Parmar Simrit; Smith Jessica; Katsoulidis Efstratios; Li Yongzhong; Sassano Antonella; Majchrzak Beata; Uddin Shahab; Tallman Martin S; Fish Eleanor N; Platanias Leonidas C
Role of protein kinase C-delta (PKC-delta) in the generation of the effects of IFN-alpha in chronic myelogenous leukemia cells.
Experimental hematology 2005;33(5):550-7.
2005: Huang Xiaoke; Chen Shan; Xu Li; Liu Yueqin; Deb Dilip K; Platanias Leonidas C; Bergan Raymond C
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells.
Cancer research 2005;65(8):3470-8.
2005: Ghias Kulsoom; Ma Chunguang; Gandhi Varsha; Platanias Leonidas C; Krett Nancy L; Rosen Steven T
8-Amino-adenosine induces loss of phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2, and Akt kinase: role in induction of apoptosis in multiple myeloma.
Molecular cancer therapeutics 2005;4(4):569-77.
2005: Li Yongzhong; Batra Sandeep; Sassano Antonella; Majchrzak Beata; Levy David E; Gaestel Matthias; Fish Eleanor N; Davis Roger J; Platanias Leonidas C
Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons.
The Journal of biological chemistry 2005;280(11):10001-10.
2005: Lal Lakhvir; Li Yongzhong; Smith Jessica; Sassano Antonella; Uddin Shahab; Parmar Simrit; Tallman Martin S; Minucci Saverio; Hay Nissim; Platanias Leonidas C
Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells.
Blood 2005;105(4):1669-77.
2005: Buonamici Silvia; Li Donglan; Mikhail Fady M; Sassano Antonella; Platanias Leonidas C; Colamonici Oscar; Anastasi John; Nucifora Giuseppina
EVI1 abrogates interferon-alpha response by selectively blocking PML induction.
The Journal of biological chemistry 2005;280(1):428-36.
2005: Parmar Simrit; Platanias Leonidas C
Interferons.
Cancer treatment and research 2005;126():45-68.
2005: Sassano Antonella; Verma Amit; Platanias Leonidas C
Mitogen-activated protein kinase pathways in interferon signaling.
Methods in molecular medicine 2005;116():135-50.
2004: Mori Yasuji; Ishida Wataru; Bhattacharyya Swati; Li Yongzhong; Platanias Leonidas C; Varga John
Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts.
Arthritis and rheumatism 2004;50(12):4008-21.
2004: Zhu Chunliu; Saberwal Gurveen; Lu Yufeng; Platanias Leonidas C; Eklund Elizabeth A
The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1.
The Journal of biological chemistry 2004;279(49):50874-85.
2004: Uddin Shahab; Platanias Leonidas C
Mechanisms of type-I interferon signal transduction.
Journal of biochemistry and molecular biology 2004;37(6):635-41.
2004: Kambhampati Suman; Verma Amit; Li Yongzhong; Parmar Simrit; Sassano Antonella; Platanias Leonidas C
Signalling pathways activated by all-trans-retinoic acid in acute promyelocytic leukemia cells.
Leukemia & lymphoma 2004;45(11):2175-85.
2004: Munshi Hidayatullah G; Wu Yi I; Mukhopadhyay Subhendu; Ottaviano Adam J; Sassano Antonella; Koblinski Jennifer E; Platanias Leonidas C; Stack M Sharon
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
The Journal of biological chemistry 2004;279(37):39042-50.
2004: Mukhopadhyay Subhendu; Munshi Hidayatullah G; Kambhampati Suman; Sassano Antonella; Platanias Leonidas C; Stack M Sharon
Calcium-induced matrix metalloproteinase 9 gene expression is differentially regulated by ERK1/2 and p38 MAPK in oral keratinocytes and oral squamous cell carcinoma.
The Journal of biological chemistry 2004;279(32):33139-46.
2004: Uddin Shahab; Hussain Azhar; Al-Hussein Khaled; Platanias Leonidas C; Bhatia Kishor G
Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.
Biochemical and biophysical research communications 2004;320(3):932-8.
2004: Srivastava Kishore K; Batra Sandeep; Sassano Antonella; Li Yongzhong; Majchrzak Beata; Kiyokawa Hiroaki; Altman Amnon; Fish Eleanor N; Platanias Leonidas C
Engagement of protein kinase C-theta in interferon signaling in T-cells.
The Journal of biological chemistry 2004;279(29):29911-20.
2004: Parmar Simrit; Katsoulidis Efstratios; Verma Amit; Li Yongzhong; Sassano Antonella; Lal Lakhvir; Majchrzak Beata; Ravandi Farhad; Tallman Martin S; Fish Eleanor N; Platanias Leonidas C
Role of the p38 mitogen-activated protein kinase pathway in the generation of the effects of imatinib mesylate (STI571) in BCR-ABL-expressing cells.
The Journal of biological chemistry 2004;279(24):25345-52.
2004: Li Yongzhong; Srivastava Kishore K; Platanias Leonidas C
Mechanisms of type I interferon signaling in normal and malignant cells.
Archivum immunologiae et therapiae experimentalis 2004;52(3):156-63.
2004: Lekmine Fatima; Sassano Antonella; Uddin Shahab; Smith Jessica; Majchrzak Beata; Brachmann Saskia M; Hay Nissim; Fish Eleanor N; Platanias Leonidas C
Interferon-gamma engages the p70 S6 kinase to regulate phosphorylation of the 40S S6 ribosomal protein.
Experimental cell research 2004;295(1):173-82.
2004: Li Yongzhong; Sassano Antonella; Majchrzak Beata; Deb Dilip K; Levy David E; Gaestel Matthias; Nebreda Angel R; Fish Eleanor N; Platanias Leonidas C
Role of p38alpha Map kinase in Type I interferon signaling.
The Journal of biological chemistry 2004;279(2):970-9.
2004: Platanias Leonidas C; Eklund Elizabeth A
Hematology grants workshop.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2004;():473-80.
2003: Verma Amit; Kambhampati Suman; Parmar Simrit; Platanias Leonidas C
Jak family of kinases in cancer.
Cancer metastasis reviews 2003;22(4):423-34.
2003: Parmar Simrit; Platanias Leonidas C
Interferons: mechanisms of action and clinical applications.
Current opinion in oncology 2003;15(6):431-9.
2003: Deonarain Raj; Verma Amit; Porter Andrew C G; Gewert Dirk R; Platanias Leonidas C; Fish Eleanor N
Critical roles for IFN-beta in lymphoid development, myelopoiesis, and tumor development: links to tumor necrosis factor alpha.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13453-8.
2003: Uddin Shahab; Lekmine Fatima; Sassano Antonella; Rui Halgeir; Fish Eleanor N; Platanias Leonidas C
Role of Stat5 in type I interferon-signaling and transcriptional regulation.
Biochemical and biophysical research communications 2003;308(2):325-30.
2003: Kambhampati Suman; Li Yongzhong; Verma Amit; Sassano Antonella; Majchrzak Beata; Deb Dilip K; Parmar Simrit; Giafis Nick; Kalvakolanu Dhananjaya V; Rahman Arshad; Uddin Shahab; Minucci Saverio; Tallman Martin S; Fish Eleanor N; Platanias Leonidas C
Activation of protein kinase C delta by all-trans-retinoic acid.
The Journal of biological chemistry 2003;278(35):32544-51.
2003: Hayes Steven A; Huang Xiaoke; Kambhampati Suman; Platanias Leonidas C; Bergan Raymond C
p38 MAP kinase modulates Smad-dependent changes in human prostate cell adhesion.
Oncogene 2003;22(31):4841-50.
2003: Deb Dilip K; Sassano Antonella; Lekmine Fatima; Majchrzak Beata; Verma Amit; Kambhampati Suman; Uddin Shahab; Rahman Arshad; Fish Eleanor N; Platanias Leonidas C
Activation of protein kinase C delta by IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(1):267-73.
2003: Lekmine Fatima; Uddin Shahab; Sassano Antonella; Parmar Simrit; Brachmann Saskia M; Majchrzak Beata; Sonenberg Nahum; Hay Nissim; Fish Eleanor N; Platanias Leonidas C
Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.
The Journal of biological chemistry 2003;278(30):27772-80.
2003: Platanias Leonidas C
Map kinase signaling pathways and hematologic malignancies.
Blood 2003;101(12):4667-79.
2003: Platanias Leonidas C
The p38 mitogen-activated protein kinase pathway and its role in interferon signaling.
Pharmacology & therapeutics 2003;98(2):129-42.
2002: Verma Amit; Mohindru Mani; Deb Dilip K; Sassano Antonella; Kambhampati Suman; Ravandi Farhad; Minucci Saverio; Kalvakolanu Dhananjaya V; Platanias Leonidas C
Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide.
The Journal of biological chemistry 2002;277(47):44988-95.
2002: Verma Amit; Stock Wendy; Lait Marcy; Ferrer Karen; Quinn John; Platanias Leonidas C
Actinomycosis presenting as an oral ulcer in a neutropenic patient.
Southern medical journal 2002;95(9):1105.
2002: Verma Amit; Deb Dilip K; Sassano Antonella; Kambhampati Suman; Wickrema Amittha; Uddin Shahab; Mohindru Mani; Van Besien Koen; Platanias Leonidas C
Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):5984-8.
2002: Roy Sanjit K; Hu Junbo; Meng Qingjun; Xia Ying; Shapiro Paul S; Reddy Sekhar P M; Platanias Leonidas C; Lindner Daniel J; Johnson Peter F; Pritchard Catrin; Pagés Gilles; Pouyssegur Jacques; Kalvakolanu Dhananjaya V
MEKK1 plays a critical role in activating the transcription factor C/EBP-beta-dependent gene expression in response to IFN-gamma.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):7945-50.
2002: Verma Amit; Platanias Leonidas C
Signaling via the interferon-alpha receptor in chronic myelogenous leukemia cells.
Leukemia & lymphoma 2002;43(4):703-9.
2002: Uddin Shahab; Sassano Antonella; Deb Dilip K; Verma Amit; Majchrzak Beata; Rahman Arshad; Malik Asrar B; Fish Eleanor N; Platanias Leonidas C
Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.
The Journal of biological chemistry 2002;277(17):14408-16.
2002: Lekmine Fatima; Sassano Antonella; Uddin Shahab; Majchrzak Beata; Miura Osamu; Druker Brian J; Fish Eleanor N; Imamoto Akira; Platanias Leonidas C
The CrkL adapter protein is required for type I interferon-dependent gene transcription and activation of the small G-protein Rap1.
Biochemical and biophysical research communications 2002;291(4):744-50.
2002: Verma Amit; Deb Dilip K; Sassano Antonella; Uddin Shahab; Varga John; Wickrema Amittha; Platanias Leonidas C
Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-beta on normal hematopoiesis.
The Journal of biological chemistry 2002;277(10):7726-35.
2002: Mahmud Dolores L; G-Amlak Maaza; Deb Dilip K; Platanias Leonidas C; Uddin Shahab; Wickrema Amittha
Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells.
Oncogene 2002;21(10):1556-62.
2002: Deonarain Raj; Chan David C M; Platanias Leonidas C; Fish Eleanor N
Interferon-alpha/beta-receptor interactions: a complex story unfolding.
Current pharmaceutical design 2002;8(24):2131-7.
2002: Verma Amit; Stock Wendy; Norohna Sandhya; Shah Rajul; Bradlow Basil; Platanias Leonidas C
Progressive transformation of germinal centers. Report of 2 cases and review of the literature.
Acta haematologica 2002;108(1):33-8.
2001: Masters J; Hinek A A; Uddin S; Platanias L C; Zeng W; McFadden G; Fish E N
Poxvirus infection rapidly activates tyrosine kinase signal transduction.
The Journal of biological chemistry 2001;276(51):48371-5.
2001: Mayer I A; Verma A; Grumbach I M; Uddin S; Lekmine F; Ravandi F; Majchrzak B; Fujita S; Fish E N; Platanias L C
The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells.
The Journal of biological chemistry 2001;276(30):28570-7.
2001: Wong M; Uddin S; Majchrzak B; Huynh T; Proudfoot A E; Platanias L C; Fish E N
Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells.
The Journal of biological chemistry 2001;276(14):11427-31.
2001: Grumbach I M; Mayer I A; Uddin S; Lekmine F; Majchrzak B; Yamauchi H; Fujita S; Druker B; Fish E N; Platanias L C
Engagement of the CrkL adaptor in interferon alpha signalling in BCR-ABL-expressing cells.
British journal of haematology 2001;112(2):327-36.
2001: Alsayed Y; Uddin S; Mahmud N; Lekmine F; Kalvakolanu D V; Minucci S; Bokoch G; Platanias L C
Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid.
The Journal of biological chemistry 2001;276(6):4012-9.
2001: Hu J; Roy S K; Shapiro P S; Rodig S R; Reddy S P; Platanias L C; Schreiber R D; Kalvakolanu D V
ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-beta-dependent gene transcription in response to interferon-gamma.
The Journal of biological chemistry 2001;276(1):287-97.
2000: Du J; Alsayed Y M; Xin F; Ackerman S J; Platanias L C
Engagement of the CrkL adapter in interleukin-5 signaling in eosinophils.
The Journal of biological chemistry 2000;275(42):33167-75.
2000: Uddin S; Lekmine F; Sharma N; Majchrzak B; Mayer I; Young P R; Bokoch G M; Fish E N; Platanias L C
The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon alpha-dependent transcriptional activation but not serine phosphorylation of Stat proteins.
The Journal of biological chemistry 2000;275(36):27634-40.
2000: Uddin S; Kottegoda S; Stigger D; Platanias L C; Wickrema A
Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitors.
Biochemical and biophysical research communications 2000;275(1):16-9.
2000: Alsayed Y; Modi S; Uddin S; Mahmud N; Druker B J; Fish E N; Hoffman R; Platanias L C
All-trans-retinoic acid induces tyrosine phosphorylation of the CrkL adapter in acute promyelocytic leukemia cells.
Experimental hematology 2000;28(7):826-32.
2000: Uddin S; Majchrzak B; Wang P C; Modi S; Khan M K; Fish E N; Platanias L C
Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
Biochemical and biophysical research communications 2000;270(1):158-62.
2000: Alsayed Y; Uddin S; Ahmad S; Majchrzak B; Druker B J; Fish E N; Platanias L C
IFN-gamma activates the C3G/Rap1 signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(4):1800-6.
2000: Usha L; Bradlow B; Stock W; Platanias L C
CD5+ immunophenotype in the bone marrow but not in the peripheral blood in a patient with hairy cell leukemia.
Acta haematologica 2000;103(4):210-3.
1999: Platanias L C; Fish E N
Signaling pathways activated by interferons.
Experimental hematology 1999;27(11):1583-92.
1999: Uddin S; Majchrzak B; Woodson J; Arunkumar P; Alsayed Y; Pine R; Young P R; Fish E N; Platanias L C
Activation of the p38 mitogen-activated protein kinase by type I interferons.
The Journal of biological chemistry 1999;274(42):30127-31.
1999: Wickrema A; Uddin S; Sharma A; Chen F; Alsayed Y; Ahmad S; Sawyer S T; Krystal G; Yi T; Nishada K; Hibi M; Hirano T; Platanias L C
Engagement of Gab1 and Gab2 in erythropoietin signaling.
The Journal of biological chemistry 1999;274(35):24469-74.
1999: Platanias L C; Uddin S; Bruno E; Korkmaz M; Ahmad S; Alsayed Y; Van Den Berg D; Druker B J; Wickrema A; Hoffman R
CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors.
Experimental hematology 1999;27(8):1315-21.
1999: Grumbach I M; Fish E N; Uddin S; Majchrzak B; Colamonici O R; Figulla H R; Heim A; Platanias L C
Activation of the Jak-Stat pathway in cells that exhibit selective sensitivity to the antiviral effects of IFN-beta compared with IFN-alpha.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(7):797-801.
1999: Wickrema A; Chen F; Namin F; Yi T; Ahmad S; Uddin S; Chen Y H; Feldman L; Stock W; Hoffman R; Platanias L C
Defective expression of the SHP-1 phosphatase in polycythemia vera.
Experimental hematology 1999;27(7):1124-32.
1999: Chen Y H; Lavelle D; DeSimone J; Uddin S; Platanias L C; Hankewych M
Growth inhibition of a human myeloma cell line by all-trans retinoic acid is not mediated through downregulation of interleukin-6 receptors but through upregulation of p21(WAF1).
Blood 1999;94(1):251-9.
1999: Nadeau O W; Domanski P; Usacheva A; Uddin S; Platanias L C; Pitha P; Raz R; Levy D; Majchrzak B; Fish E; Colamonici O R
The proximal tyrosines of the cytoplasmic domain of the beta chain of the type I interferon receptor are essential for signal transducer and activator of transcription (Stat) 2 activation. Evidence that two Stat2 sites are required to reach a threshold of interferon alpha-induced Stat2 tyrosine phosphorylation that allows normal formation of interferon-stimulated gene factor 3.
The Journal of biological chemistry 1999;274(7):4045-52.
1999: Fish E N; Uddin S; Korkmaz M; Majchrzak B; Druker B J; Platanias L C
Activation of a CrkL-stat5 signaling complex by type I interferons.
The Journal of biological chemistry 1999;274(2):571-3.
1998: Uddin S; Grumbach I M; Yi T; Colamonici O R; Platanias L C
Interferon alpha activates the tyrosine kinase Lyn in haemopoietic cells.
British journal of haematology 1998;101(3):446-9.
1998: Platanias L C; Domanski P; Nadeau O W; Yi T; Uddin S; Fish E; Neel B G; Colamonici O R
Identification of a domain in the beta subunit of the type I interferon (IFN) receptor that exhibits a negative regulatory effect in the growth inhibitory action of type I IFNs.
The Journal of biological chemistry 1998;273(10):5577-81.
1998: Domanski P; Nadeau O W; Platanias L C; Fish E; Kellum M; Pitha P; Colamonici O R
Differential use of the betaL subunit of the type I interferon (IFN) receptor determines signaling specificity for IFNalpha2 and IFNbeta.
The Journal of biological chemistry 1998;273(6):3144-7.
1998: Sun W H; Pabon C; Alsayed Y; Huang P P; Jandeska S; Uddin S; Platanias L C; Rosen S T
Interferon-alpha resistance in a cutaneous T-cell lymphoma cell line is associated with lack of STAT1 expression.
Blood 1998;91(2):570-6.
1997: Ahmad S; Alsayed Y M; Druker B J; Platanias L C
The type I interferon receptor mediates tyrosine phosphorylation of the CrkL adaptor protein.
The Journal of biological chemistry 1997;272(48):29991-4.
1997: Domanski P; Fish E; Nadeau O W; Witte M; Platanias L C; Yan H; Krolewski J; Pitha P; Colamonici O R
A region of the beta subunit of the interferon alpha receptor different from box 1 interacts with Jak1 and is sufficient to activate the Jak-Stat pathway and induce an antiviral state.
The Journal of biological chemistry 1997;272(42):26388-93.
1997: Uddin S; Fish E N; Sher D; Gardziola C; Colamonici O R; Kellum M; Pitha P M; White M F; Platanias L C
The IRS-pathway operates distinctively from the Stat-pathway in hematopoietic cells and transduces common and distinct signals during engagement of the insulin or interferon-alpha receptors.
Blood 1997;90(7):2574-82.
1997: Uddin S; Sher D A; Alsayed Y; Pons S; Colamonici O R; Fish E N; White M F; Platanias L C
Interaction of p59fyn with interferon-activated Jak kinases.
Biochemical and biophysical research communications 1997;235(1):83-8.
1997: Uddin S; Fish E N; Sher D A; Gardziola C; White M F; Platanias L C
Activation of the phosphatidylinositol 3-kinase serine kinase by IFN-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2390-7.
1997: Uddin S; Sweet M; Colamonici O R; Krolewski J J; Platanias L C
The vav proto-oncogene product (p95vav) interacts with the Tyk-2 protein tyrosine kinase.
FEBS letters 1997;403(1):31-4.
1996: Jiao H; Berrada K; Yang W; Tabrizi M; Platanias L C; Yi T
Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1.
Molecular and cellular biology 1996;16(12):6985-92.
1996: Platanias L C; Uddin S; Domanski P; Colamonici O R
Differences in interferon alpha and beta signaling. Interferon beta selectively induces the interaction of the alpha and betaL subunits of the type I interferon receptor.
The Journal of biological chemistry 1996;271(39):23630-3.
1996: Uddin S; Gardziola C; Dangat A; Yi T; Platanias L C
Interaction of the c-cbl proto-oncogene product with the Tyk-2 protein tyrosine kinase.
Biochemical and biophysical research communications 1996;225(3):833-8.
1996: Uddin S; Yetter A; Katzav S; Hofmann C; White M F; Platanias L C
Insulin-like growth factor-1 induces rapid tyrosine phosphorylation of the vav proto-oncogene product.
Experimental hematology 1996;24(5):622-7.
1996: Platanias L C; Uddin S; Yetter A; Sun X J; White M F
The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2.
The Journal of biological chemistry 1996;271(1):278-82.
1995: Uddin S; Chamdin A; Platanias L C
Interaction of the transcriptional activator Stat-2 with the type I interferon receptor.
The Journal of biological chemistry 1995;270(42):24627-30.
1995: Yetter A; Uddin S; Krolewski J J; Jiao H; Yi T; Platanias L C
Association of the interferon-dependent tyrosine kinase Tyk-2 with the hematopoietic cell phosphatase.
The Journal of biological chemistry 1995;270(31):18179-82.
1995: Uddin S; Yenush L; Sun X J; Sweet M E; White M F; Platanias L C
Interferon-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3'-kinase.
The Journal of biological chemistry 1995;270(27):15938-41.
1995: Colamonici O R; Platanias L C; Domanski P; Handa R; Gilmour K C; Diaz M O; Reich N; Pitha-Rowe P
Transmembrane signaling by the alpha subunit of the type I interferon receptor is essential for activation of the JAK kinases and the transcriptional factor ISGF3.
The Journal of biological chemistry 1995;270(14):8188-93.
1995: Uddin S; Katzav S; White M F; Platanias L C
Insulin-dependent tyrosine phosphorylation of the vav protooncogene product in cells of hematopoietic origin.
The Journal of biological chemistry 1995;270(13):7712-6.
1994: Platanias L C; Uddin S; Colamonici O R
Tyrosine phosphorylation of the alpha and beta subunits of the type I interferon receptor. Interferon-beta selectively induces tyrosine phosphorylation of an alpha subunit-associated protein.
The Journal of biological chemistry 1994;269(27):17761-4.
1994: Colamonici O R; Domanski P; Krolewski J J; Fu X Y; Reich N C; Pfeffer L M; Sweet M E; Platanias L C
Interferon alpha (IFN alpha) signaling in cells expressing the variant form of the type I IFN receptor.
The Journal of biological chemistry 1994;269(8):5660-5.
1994: Platanias L C; Sweet M E
Interferon alpha induces rapid tyrosine phosphorylation of the vav proto-oncogene product in hematopoietic cells.
The Journal of biological chemistry 1994;269(5):3143-6.
1993: Platanias L C; Golomb H M
Hairy cell leukaemia.
Baillière's clinical haematology 1993;6(4):887-98.
1993: Platanias L C; Pfeffer L M; Cruciani R; Colamonici O R
Characterization of the alpha subunit of the IFN-alpha receptor. Evidence of N- and O-linked glycosylation and association with other surface proteins.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(8 Pt 1):3382-8.
1992: Platanias L C; Pfeffer L M; Barton K P; Vardiman J W; Golomb H M; Colamonici O R
Expression of the IFN alpha receptor in hairy cell leukaemia.
British journal of haematology 1992;82(3):541-6.
1992: Platanias L C; Colamonici O R
Interferon alpha induces rapid tyrosine phosphorylation of the alpha subunit of its receptor.
The Journal of biological chemistry 1992;267(33):24053-7.
1992: Colamonici O R; Domanski P; Platanias L C; Diaz M O
Correlation between interferon (IFN) alpha resistance and deletion of the IFN alpha/beta genes in acute leukemia cell lines suggests selection against the IFN system.
Blood 1992;80(3):744-9.
1992: Colamonici O R; Pfeffer L M; D'Alessandro F; Platanias L C; Gregory S A; Rosolen A; Nordan R; Cruciani R A; Diaz M O
Multichain structure of the IFN-alpha receptor on hematopoietic cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(7):2126-32.
1991: Platanias L C; Ratain M J
Hairy cell leukaemia: the role of alpha interferon.
European journal of cancer (Oxford, England : 1990) 1991;27 Suppl 4():S53-7.
1990: Platanias L C; Larson R A; Vardiman J W; Reisel H; Golomb H M; McKeithan T W
Complex rearrangement of the T cell receptor in large granular lymphocytosis associated with myeloid suppression.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1990;4(12):863-5.

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