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Robin Plevin

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Juliane Schroeder; Stuart Woods; H Adrienne McGachy; Robin Plevin; James Alexander
T cell hypo-responsiveness against Leishmania major in MAP kinase phosphatase (MKP) 2 deficient C57BL/6 mice does not alter the healer disease phenotype.
Anne Crilly; Lynette Dunning; John C Lockhart; Iain B McInnes; Mohammad B Nickdel; Helen Palmer; Robin Plevin; William R Ferrell
Immunomodulatory role of proteinase-activated receptor-2.
Lewis MacKenzie; Peter McArdle; Pamela McCall; Andrew Paul; Robin Plevin; Morag Seywright; Claire Tanahill; Mark Underwood; Claire Adams; Jamie Catlow; Sophia Hatziieremia; Simon Mackay; Joanne Edwards
Nuclear factor κB predicts poor outcome in patients with hormone-naive prostate cancer with high nuclear androgen receptor.

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All Publications

2013: Juliane Schroeder; Stuart Woods; H Adrienne McGachy; Robin Plevin; James Alexander
T cell hypo-responsiveness against Leishmania major in MAP kinase phosphatase (MKP) 2 deficient C57BL/6 mice does not alter the healer disease phenotype.
PLoS neglected tropical diseases 2013;7(2):e2064.
2012: Anne Crilly; Lynette Dunning; John C Lockhart; Iain B McInnes; Mohammad B Nickdel; Helen Palmer; Robin Plevin; William R Ferrell
Immunomodulatory role of proteinase-activated receptor-2.
Annals of the rheumatic diseases 2012;71(9):1559-66.
2012: Lewis MacKenzie; Peter McArdle; Pamela McCall; Andrew Paul; Robin Plevin; Morag Seywright; Claire Tanahill; Mark Underwood; Claire Adams; Jamie Catlow; Sophia Hatziieremia; Simon Mackay; Joanne Edwards
Nuclear factor κB predicts poor outcome in patients with hormone-naive prostate cancer with high nuclear androgen receptor.
Human pathology 2012;43(9):1491-500.
2012: Margaret R Cunningham; Gwyn W Gould; Kathryn A McIntosh; Graeme Milligan; Stuart Mundell; Mary Nilsson; John D Pediani; Alexandra E Cooke; Joris Robben; Robin Plevin
Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4).
The Journal of biological chemistry 2012;287(20):16656-69.
2012: Ahmed Lawan; Thikryat Neamatallah; Sameer Al-Harthi; Sulaiman Alnasser; Juliane Schroeder; Muhannad Shweash; Emma Torrance; Robin Plevin
MKP-2: out of the DUSP-bin and back into the limelight.
Biochemical Society transactions 2012;40(1):235-9.
2012: Carly Gamble; Ka Ho Ho; Kathryn McIntosh; Robin Plevin; Rebecca Scott; Andrew Paul
Inhibitory kappa B Kinases as targets for pharmacological regulation.
British journal of pharmacology 2012;165(4):802-19.
2012: Shalmali Patkar; Robin Plevin; Rothwelle Tate; Michel Modo; Hilary V O Carswell
Conditionally immortalised neural stem cells promote functional recovery and brain plasticity after transient focal cerebral ischaemia in mice.
Stem cell research 2012;8(1):14-25.
2011: Muhannad Shweash; Juliane Schroeder; H Adrienne McGachy; James Alexander; Clare E Bryant; Owain Millington; Jeremy C Mottram; Thikryat Neamatallah; Robin Plevin
Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression.
Molecular immunology 2011;48(15-16):1800-8.
2011: Ahmed Lawan; Sameer Al-Harthi; Laurence Cadalbert; Anthony G McCluskey; Muhannad Shweash; Gianluca Grassia; Anne Grant; Marie Boyd; Susan Currie; Robin Plevin
Deletion of the dual specific phosphatase-4 (DUSP-4) gene reveals an essential non-redundant role for MAP kinase phosphatase-2 (MKP-2) in proliferation and cell survival.
The Journal of biological chemistry 2011;286(15):12933-43.
2010: William R Ferrell; Elizabeth B Kelso; John C Lockhart; Robin Plevin; Iain B McInnes
Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis.
Annals of the rheumatic diseases 2010;69(11):2051-4.
2010: Mashael Al-Mutairi; Sameer Al-Harthi; Laurence Cadalbert; Robin Plevin
Over-expression of mitogen-activated protein kinase phosphatase-2 enhances adhesion molecule expression and protects against apoptosis in human endothelial cells.
British journal of pharmacology 2010;161(4):782-98.
2010: Jennifer M Milner; Amit Patel; Rosemary Davidson; Tracey E Swingler; Antoine Desilets; David A Young; Elizabeth B Kelso; Simon T Donell; Tim E Cawston; Ian Clark; William R Ferrell; Robin Plevin; John C Lockhart; Richard Leduc; Andrew D Rowan
Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis.
Arthritis and rheumatism 2010;62(7):1955-66.
2010: Laurence C Cadalbert; Callum Sloss; Margaret Cunningham; Mashael Al-Mutairi; Alan McIntire; Janet Shipley; Robin Plevin
Differential regulation of MAP kinase activation by a novel splice variant of human MAP kinase phosphatase-2.
Cellular signalling 2010;22(3):357-65.
2010: Kathryn McIntosh; Margaret R Cunningham; Laurence Cadalbert; John Lockhart; Gary Boyd; William R Ferrell; Robin Plevin
Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRs.
Cellular signalling 2010;22(2):265-73.
2010: Mashael S Al-Mutairi; Laurence C Cadalbert; H Adrienne McGachy; Muhannad Shweash; Juliane Schroeder; Magdalena Kurnik; Callum Sloss; Clare E Bryant; James Alexander; Robin Plevin
MAP kinase phosphatase-2 plays a critical role in response to infection by Leishmania mexicana.
PLoS pathogens 2010;6(11):e1001192.
2009: Fui Goon Goh; Pei Yuen Ng; Mary Nilsson; Toru Kanke; Robin Plevin
Dual effect of the novel peptide antagonist K-14585 on proteinase-activated receptor-2-mediated signalling.
British journal of pharmacology 2009;158(7):1695-704.
2009: Toru Kanke; Mototsugu Kabeya; Satoko Kubo; S Kondo; K Yasuoka; J Tagashira; H Ishiwata; Masako Saka; T Furuyama; T Nishiyama; T Doi; Yukio Hattori; Atsufumi Kawabata; M R Cunningham; Robin Plevin
Novel antagonists for proteinase-activated receptor 2: inhibition of cellular and vascular responses in vitro and in vivo.
British journal of pharmacology 2009;158(1):361-71.
2008: T K Monaghan; C Pou; Christopher J MacKenzie; Robin Plevin; Eve M Lutz
Neurotrophic actions of PACAP-38 and LIF on human neuroblastoma SH-SY5Y cells.
Journal of molecular neuroscience : MN 2008;36(1-3):45-56.
2008: Fui Goon Goh; Callum Sloss; Margaret Cunningham; Mary Nilsson; Laurence Cadalbert; Robin Plevin
G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 NFkappaB serine 536 phosphorylation in human keratinocytes.
Cellular signalling 2008;20(7):1267-74.
2008: T K Monaghan; Christopher J MacKenzie; Robin Plevin; Eve M Lutz
PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases.
Journal of neurochemistry 2008;104(1):74-88.
2007: H S Palmer; Elizabeth Kelso; John C Lockhart; Christian P Sommerhoff; Robin Plevin; F G Goh; William R Ferrell
Protease-activated receptor 2 mediates the proinflammatory effects of synovial mast cells.
Arthritis and rheumatism 2007;56(11):3532-40.
2007: Fatema Habeeb; Graham Stables; Fiona Bradbury; Stephanie Nong; Pamela Cameron; Robin Plevin; Valerie A Ferro
The inner gel component of Aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells.
Methods (San Diego, Calif.) 2007;42(4):388-93.
2007: Kathryn A McIntosh; Robin Plevin; William R Ferrell; John C Lockhart
The therapeutic potential of proteinase-activated receptors in arthritis.
Current opinion in pharmacology 2007;7(3):334-8.
2007: E Ritchie; Masako Saka; Christopher MacKenzie; Robert M Drummond; C Wheeler-Jones; Toru Kanke; Robin Plevin
Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells.
British journal of pharmacology 2007;150(8):1044-54.
2007: Christopher J MacKenzie; Elwyn Ritchie; Andrew Paul; Robin Plevin
IKKalpha and IKKbeta function in TNFalpha-stimulated adhesion molecule expression in human aortic smooth muscle cells.
Cellular signalling 2007;19(1):75-80.
2006: S Hatziieremia; Alexander I Gray; Valerie A Ferro; Andrew Paul; Robin Plevin
The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages.
British journal of pharmacology 2006;149(2):188-98.
2006: Trevor J Bushell; Robin Plevin; stuart cobb; Andrew J Irving
Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes.
Neuropharmacology 2006;50(6):714-25.
2006: Tomoko Smyth; Hayley J Harris; Andrew Brown; Sabine Tötemeyer; Belinda A Farnfield; Duncan J Maskell; Makoto Matsumoto; Robin Plevin; Louise C Alldridge; Clare E Bryant
Differential modulatory effects of annexin 1 on nitric oxide synthase induction by lipopolysaccharide in macrophages.
Immunology 2006;117(3):340-9.
2006: Elizabeth Kelso; John C Lockhart; Todd Hembrough; Lynette Dunning; Robin Plevin; Morley D Hollenberg; Christian P Sommerhoff; John S McLean; William R Ferrell
Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation.
The Journal of pharmacology and experimental therapeutics 2006;316(3):1017-24.
2005: Laurence Cadalbert; Callum Sloss; Pamela Cameron; Robin Plevin
Conditional expression of MAP kinase phosphatase-2 protects against genotoxic stress-induced apoptosis by binding and selective dephosphorylation of nuclear activated c-jun N-terminal kinase.
Cellular signalling 2005;17(10):1254-64.
2005: Almudena Bermejo Gomez; Christopher MacKenzie; Andrew Paul; Robin Plevin
Selective inhibition of inhibitory kappa B kinase-beta abrogates induction of nitric oxide synthase in lipopolysaccharide-stimulated rat aortic smooth muscle cells.
British journal of pharmacology 2005;146(2):217-25.
2005: Scott R Macfarlane; Callum Sloss; Pamela Cameron; Toru Kanke; Roderick C McKenzie; Robin Plevin
The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes.
British journal of pharmacology 2005;145(4):535-44.
2005: Callum Sloss; Laurence Cadalbert; Stephen G Finn; Stephen J Fuller; Robin Plevin
Disruption of two putative nuclear localization sequences is required for cytosolic localization of mitogen-activated protein kinase phosphatase-2.
Cellular signalling 2005;17(6):709-16.
2005: Toru Kanke; Hiroyuki Ishiwata; Mototsugu Kabeya; Masako Saka; Takeshi Doi; Yukio Hattori; Atsufumi Kawabata; Robin Plevin
Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, [3H]2-furoyl-LIGRL-NH2, to human PAR2.
British journal of pharmacology 2005;145(2):255-63.
2004: Pamela Cameron; Adrienne McGachy; Mary Anderson; Andrew Paul; Graham H Coombs; Jeremy C Mottram; James Alexander; Robin Plevin
Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3297-304.
2004: Hamid Reza Kazerani; Robin Plevin; Junichi Kawagoe; Toru Kanke; Brian L Furman
Lack of effect of proteinase-activated receptor-2 (PAR-2) deletion on the pathophysiological changes produced by lipopolysaccharide in the mouse: comparison with dexamethasone.
The Journal of pharmacy and pharmacology 2004;56(8):1015-20.
2004: Atsufumi Kawabata; Toru Kanke; Daiki Yonezawa; Tsuyoshi Ishiki; Masako Saka; Mototsugu Kabeya; Fumiko Sekiguchi; Satoko Kubo; Ryotaro Kuroda; Masahiro Iwaki; Kousaku Katsura; Robin Plevin
Potent and metabolically stable agonists for protease-activated receptor-2: evaluation of activity in multiple assay systems in vitro and in vivo.
The Journal of pharmacology and experimental therapeutics 2004;309(3):1098-107.
2004: Michael J Seatter; Robert M Drummond; Toru Kanke; Scott R Macfarlane; Morley D Hollenberg; Robin Plevin
The role of the C-terminal tail in protease-activated receptor-2-mediated Ca2+ signalling, proline-rich tyrosine kinase-2 activation, and mitogen-activated protein kinase activity.
Cellular signalling 2004;16(1):21-9.
2003: Pamela Cameron; Susan J Smith; Mark A Giembycz; Dino Rotondo; Robin Plevin
Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release.
British journal of pharmacology 2003;140(7):1320-30.
2003: Christopher J MacKenzie; Andrew Paul; Susan Wilson; Rainer de Martin; Andrew H Baker; Robin Plevin
Enhancement of lipopolysaccharide-stimulated JNK activity in rat aortic smooth muscle cells by pharmacological and adenovirus-mediated inhibition of inhibitory kappa B kinase signalling.
British journal of pharmacology 2003;139(5):1041-9.
2003: William R Ferrell; John C Lockhart; Elizabeth Kelso; Lynette Dunning; Robin Plevin; Stephen E Meek; Andrew J H Smith; Gary D Hunter; John S McLean; Frances McGarry; Robert Ramage; Lu Jiang; Toru Kanke; Junichi Kawagoe
Essential role for proteinase-activated receptor-2 in arthritis.
The Journal of clinical investigation 2003;111(1):35-41.
2002: Pamela Cameron; Deborah Bingham; Andrew Paul; Martin Pavelka; Scott Cameron; Dino Rotondo; Robin Plevin
Essential role for verotoxin in sustained stress-activated protein kinase and nuclear factor kappa B signaling, stimulated by Escherichia coli O157:H7 in Vero cells.
Infection and immunity 2002;70(10):5370-80.
2002: Junichi Kawagoe; Toshiaki Takizawa; Jiro Matsumoto; Masaki Tamiya; Stephen E Meek; Andrew J H Smith; Gary D Hunter; Robin Plevin; Naohiro Saito; Toru Kanke; Mikio Fujii; Yasushi Wada
Effect of protease-activated receptor-2 deficiency on allergic dermatitis in the mouse ear.
Japanese journal of pharmacology 2002;88(1):77-84.
2001: L Liu; Andrew Paul; Christopher J MacKenzie; C Bryant; Anne Graham; Robin Plevin
Nuclear factor kappa B is involved in lipopolysaccharide-stimulated induction of interferon regulatory factor-1 and GAS/GAF DNA-binding in human umbilical vein endothelial cells.
British journal of pharmacology 2001;134(8):1629-38.
2001: L J Torrie; Christopher J MacKenzie; Andrew Paul; Robin Plevin
Hydrogen peroxide-mediated inhibition of lipopolysaccharide-stimulated inhibitory kappa B kinase activity in rat aortic smooth muscle cells.
British journal of pharmacology 2001;134(2):393-401.
2001: Toru Kanke; Scott R Macfarlane; Michael J Seatter; E Davenport; Andrew Paul; R C McKenzie; Robin Plevin
Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes.
The Journal of biological chemistry 2001;276(34):31657-66.
2001: Scott R Macfarlane; Michael J Seatter; Toru Kanke; Gary D Hunter; Robin Plevin
Proteinase-activated receptors.
Pharmacological reviews 2001;53(2):245-82.
2001: C J Robinson; Callum Sloss; Robin Plevin
Inactivation of JNK activity by mitogen-activated protein kinase phosphatase-2 in EAhy926 endothelial cells is dependent upon agonist-specific JNK translocation to the nucleus.
Cellular signalling 2001;13(1):29-41.
2000: Andrew Paul; L J Torrie; GJ McLaren; Charles Kennedy; G W Gould; Robin Plevin
P2Y receptor-mediated inhibition of tumor necrosis factor alpha -stimulated stress-activated protein kinase activity in EAhy926 endothelial cells.
The Journal of biological chemistry 2000;275(18):13243-9.
1999: Louise C Alldridge; H J Harris; Robin Plevin; R Hannon; Clare E Bryant
The annexin protein lipocortin 1 regulates the MAPK/ERK pathway.
The Journal of biological chemistry 1999;274(53):37620-8.
1999: Vera P Krymskaya; Raymond B Penn; MJ Orsini; P H Scott; Robin Plevin; Trevor R Walker; Andrew Eszterhas; Yassine Amrani; Edwin R Chilvers; Reynold A Panettieri
Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation.
The American journal of physiology 1999;277(1 Pt 1):L65-78.
1999: Andrew Paul; A Cuenda; Clare E Bryant; J Murray; Edwin R Chilvers; P Cohen; GW Gould; Robin Plevin
Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages.
Cellular signalling 1999;11(7):491-7.
1998: David J Welsh; P Scott; Robin Plevin; Roger M Wadsworth; Andrew J Peacock
Hypoxia enhances cellular proliferation and inositol 1,4, 5-triphosphate generation in fibroblasts from bovine pulmonary artery but not from mesenteric artery.
American journal of respiratory and critical care medicine 1998;158(6):1757-62.
1998: Pamela H Scott; Andrew Paul; CM Belham; Andrew J Peacock; Roger M Wadsworth; GW Gould; D Welsh; Robin Plevin
Hypoxic stimulation of the stress-activated protein kinases in pulmonary artery fibroblasts.
American journal of respiratory and critical care medicine 1998;158(3):958-62.
1998: S M Laird; Anne Graham; Andrew Paul; GW Gould; C Kennedy; Robin Plevin
Tumour necrosis factor stimulates stress-activated protein kinases and the inhibition of DNA synthesis in cultures of bovine aortic endothelial cells.
Cellular signalling 1998;10(7):473-80.
1998: Andrew J Peacock; P Scott; Robin Plevin; Roger M Wadsworth; D Welsh
Hypoxia enhances proliferation and generation of IP3 in pulmonary artery fibroblasts but not in those from the mesenteric circulation.
Chest 1998;114(1 Suppl):24S.
1997: Andrew Paul; S Wilson; CM Belham; C J Robinson; Pamela H Scott; GW Gould; Robin Plevin
Stress-activated protein kinases: activation, regulation and function.
Cellular signalling 1997;9(6):403-10.
1997: Fiona Thomson; Thomas Jess; C Moyes; Robin Plevin; Gwyn W Gould
Evidence for ras- and rho-dependent pathways in the regulation of glucose transport by growth factors.
Biochemical Society transactions 1997;25(3):472S.
1997: Fiona Thomson; Thomas Jess; C Moyes; Robin Plevin; Gwyn W Gould
Characterization of the intracellular signalling pathways that underlie growth-factor-stimulated glucose transport in Xenopus oocytes: evidence for ras- and rho-dependent pathways of phosphatidylinositol 3-kinase activation.
The Biochemical journal 1997;325 ( Pt 3)():637-43.
1997: Robin Plevin; K Malarkey; D Aidulis; A McLees; GW Gould
Cyclic AMP inhibitors inhibits PDGF-stimulated mitogen-activated protein kinase activity in rat aortic smooth muscle cells via inactivation of c-Raf-1 kinase and induction of MAP kinase phosphatase-1.
Cellular signalling 1997;9(3-4):323-8.
1997: Alan Pemberton; CM Belham; John F Huntley; Robin Plevin; Hugh Miller
Sheep mast cell proteinase-1, a serine proteinase with both tryptase- and chymase-like properties, is inhibited by plasma proteinase inhibitors and is mitogenic for bovine pulmonary artery fibroblasts.
The Biochemical journal 1997;323 ( Pt 3)():719-25.
1997: Andrew Paul; C Bryant; MF Lawson; Edwin R Chilvers; Robin Plevin
Dissociation of lipopolysaccharide-mediated induction of nitric oxide synthase and inhibition of DNA synthesis in RAW 264.7 macrophages and rat aortic smooth muscle cells.
British journal of pharmacology 1997;120(8):1439-44.
1997: Andrew Paul; K Doherty; Robin Plevin
Differential regulation by protein kinase C isoforms of nitric oxide synthase induction in RAW 264.7 macrophages and rat aortic smooth muscle cells.
British journal of pharmacology 1997;120(5):940-6.
1997: Pamela H Scott; CM Belham; Andrew J Peacock; Robin Plevin
Intracellular signalling pathways that regulate vascular cell proliferation: effect of hypoxia.
Experimental physiology 1997;82(2):317-26.
1997: CM Belham; Pamela H Scott; D P Twomey; GW Gould; Roger M Wadsworth; Robin Plevin
Evidence that thrombin-stimulated DNA synthesis in pulmonary arterial fibroblasts involves phosphatidylinositol 3-kinase-dependent p70 ribosomal S6 kinase activation.
Cellular signalling 1997;9(1):109-16.
1996: CM Belham; Rothwelle J Tate; Pamela H Scott; Alan Pemberton; Hugh Miller; Roger M Wadsworth; G W Gould; Robin Plevin
Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases.
The Biochemical journal 1996;320 ( Pt 3)():939-46.
1996: C J Robinson; Pamela H Scott; A B Allan; Thomas Jess; G W Gould; Robin Plevin
Treatment of vascular smooth muscle cells with antisense phosphorothioate oligodeoxynucleotides directed against p42 and p44 mitogen-activated protein kinases abolishes DNA synthesis in response to platelet-derived growth factor.
The Biochemical journal 1996;320 ( Pt 1)():123-7.
1996: Pamela H Scott; CM Belham; J al-Hafidh; Edwin R Chilvers; Andrew J Peacock; G W Gould; Robin Plevin
A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells.
The Biochemical journal 1996;318 ( Pt 3)():965-71.
1996: Robin Plevin; Pamela H Scott; C J Robinson; G W Gould
Efficacy of agonist-stimulated MEK activation determines the susceptibility of mitogen-activated protein (MAP) kinase to inhibition in rat aortic smooth muscle cells.
The Biochemical journal 1996;318 ( Pt 2)():657-63.
1996: Thomas Jess; CM Belham; Fiona Thomson; Pamela H Scott; Robin Plevin; G W Gould
Phosphatidylinositol 3'-kinase, but not p70 ribosomal S6 kinase, is involved in membrane protein recycling: wortmannin inhibits glucose transport and downregulates cell-surface transferrin receptor numbers independently of any effect on fluid-phase endocytosis in fibroblasts.
Cellular signalling 1996;8(4):297-304.
1996: Fiona Thomson; C Moyes; Pamela H Scott; Robin Plevin; G W Gould
Lysophosphatidic acid stimulates glucose transport in Xenopus oocytes via a phosphatidylinositol 3'-kinase with distinct properties.
The Biochemical journal 1996;316 ( Pt 1)():161-6.
1996: Anne Graham; A McLees; K Malarkey; G W Gould; Robin Plevin
Role of receptor desensitization, phosphatase induction and intracellular cyclic AMP in the termination of mitogen-activated protein kinase activity in UTP-stimulated EAhy 926 endothelial cells.
The Biochemical journal 1996;315 ( Pt 2)():563-9.
1996: Anne Graham; A McLees; C Kennedy; G W Gould; Robin Plevin
Stimulation by the nucleotides, ATP and UTP of mitogen-activated protein kinase in EAhy 926 endothelial cells.
British journal of pharmacology 1996;117(6):1341-7.
1996: K Malarkey; A McLees; Andrew Paul; G W Gould; Robin Plevin
The role of protein kinase C in activation and termination of mitogen-activated protein kinase activity in angiotensin II-stimulated rat aortic smooth-muscle cells.
Cellular signalling 1996;8(2):123-9.
1995: A Paul; Robin Plevin
Cell signalling events involved in mediating the induction of nitric oxide synthase in macrophages and vascular smooth muscle cells.
Biochemical Society transactions 1995;23(4):1029-33.
1995: K Malarkey; Edwin R Chilvers; M F Lawson; Robin Plevin
Stimulation by endothelin-1 of mitogen-activated protein kinases and DNA synthesis in bovine tracheal smooth muscle cells.
British journal of pharmacology 1995;116(4):2267-73.
1995: K Malarkey; CM Belham; Andrew Paul; Anne Graham; A McLees; Pamela H Scott; Robin Plevin
The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors.
The Biochemical journal 1995;309 ( Pt 2)():361-75.
1995: Asif Ahmed; M A Shoaibi; Robin Plevin; Stephen K Smith
Oestradiol-17 beta modulates PAF-evoked phospholipase D activity but not inositide-lipid hydrolysis in human endometrial cell line, HEC-1B.
Cellular signalling 1995;7(4):403-9.
1995: A McLees; Anne Graham; K Malarkey; G W Gould; Robin Plevin
Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of mitogen-activated protein kinase by protein kinase C- and pertussis toxin-dependent pathways in the endothelial cell line EAhy 926.
The Biochemical journal 1995;307 ( Pt 3)():743-8.
1995: D M Aidulis; K Malarkey; A McLees; G W Gould; Robin Plevin
The permissive effect of serum on the inhibition of mitogen-activated protein kinase by forskolin in vascular smooth muscle cells.
Biochemical Society transactions 1995;23(2):341S.
1995: A McLees; Anne Graham; K Malarkey; G W Gould; Robin Plevin
Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of pp42 mitogen-activated protein kinase by protein kinase C and protein kinase A in EAhy926 cells.
Biochemical Society transactions 1995;23(2):339S.
1995: A Paul; R H Pendreigh; Robin Plevin
Protein kinase C and tyrosine kinase pathways regulate lipopolysaccharide-induced nitric oxide synthase activity in RAW 264.7 murine macrophages.
British journal of pharmacology 1995;114(2):482-8.
1994: G W Gould; Thomas Jess; glenn andrews; J J Herbst; Robin Plevin; E Michael Gibbs
Evidence for a role of phosphatidylinositol 3-kinase in the regulation of glucose transport in Xenopus oocytes.
The Journal of biological chemistry 1994;269(43):26622-5.
1994: D Stephen Charnock-Jones; Andrew M Sharkey; C A Boocock; Asif Ahmed; Robin Plevin; N Ferrara; Stephen K Smith
Vascular endothelial growth factor receptor localization and activation in human trophoblast and choriocarcinoma cells.
Biology of reproduction 1994;51(3):524-30.
1994: M K Saville; Anne Graham; K Malarkey; A Paterson; G W Gould; Robin Plevin
Regulation of endothelin-1- and lysophosphatidic acid-stimulated tyrosine phosphorylation of focal adhesion kinase (pp125fak) in Rat-1 fibroblasts.
The Biochemical journal 1994;301 ( Pt 2)():407-14.
1994: Asif Ahmed; S O Sage; Robin Plevin; M A Shoaibi; A M Sharkey; Stephen K Smith
Functional platelet-activating factor receptors linked to inositol lipid hydrolysis, calcium mobilization and tyrosine kinase activity in the human endometrial HEC-1B cell line.
Journal of reproduction and fertility 1994;101(2):459-66.
1994: Robin Plevin; N A Kellock; M J Wakelam; Roger M Wadsworth
Regulation by hypoxia of endothelin-1-stimulated phospholipase D activity in sheep pulmonary artery cultured smooth muscle cells.
British journal of pharmacology 1994;112(1):311-5.
1994: G W Gould; N W Merrall; Sally Martin; Thomas Jess; I W Campbell; D M Calderhead; E Michael Gibbs; G D Holman; Robin Plevin
Growth factor-induced stimulation of hexose transport in 3T3-L1 adipocytes: evidence that insulin-induced translocation of GLUT4 is independent of activation of MAP kinase.
Cellular signalling 1994;6(3):313-20.
1994: C P Briscoe; Robin Plevin; Michael J O Wakelam
Rapid desensitization and resensitization of bombesin-stimulated phospholipase D activity in Swiss 3T3 cells.
The Biochemical journal 1994;298 ( Pt 1)():61-7.
1994: Asif Ahmed; Robin Plevin; M A Shoaibi; S A Fountain; R A Ferriani; Stephen K Smith
Basic FGF activates phospholipase D in endothelial cells in the absence of inositol-lipid hydrolysis.
The American journal of physiology 1994;266(1 Pt 1):C206-12.
1993: N W Merrall; Robin Plevin; G W Gould
Growth factors, mitogens, oncogenes and the regulation of glucose transport.
Cellular signalling 1993;5(6):667-75.
1993: N W Merrall; Robin Plevin; G W Gould
MAP kinase may play a role in the early phase of glucose transport in insulin treated 3T3-L1 fibroblasts.
Biochemical Society transactions 1993;21(4):355S.
1993: N W Merrall; Robin Plevin; David Stokoe; P Cohen; A R Nebreda; G W Gould
Mitogen-activated protein kinase (MAP kinase), MAP kinase kinase and c-Mos stimulate glucose transport in Xenopus oocytes.
The Biochemical journal 1993;295 ( Pt 2)():351-5.
1993: N W Merrall; Michael J O Wakelam; Robin Plevin; G W Gould
Insulin and platelet-derived growth factor acutely stimulate glucose transport in 3T3-L1 fibroblasts independently of protein kinase C.
Biochimica et biophysica acta 1993;1177(2):191-8.
1992: Robin Plevin; A Stewart; A Paul; Michael J O Wakelam
Vasopressin-stimulated [3H]-inositol phosphate and [3H]-phosphatidylbutanol accumulation in A10 vascular smooth muscle cells.
British journal of pharmacology 1992;107(1):109-15.
1992: Robin Plevin; Michael J O Wakelam
Rapid desensitization of vasopressin-stimulated phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine hydrolysis questions the role of these pathways in sustained diacylglycerol formation in A10 vascular-smooth-muscle cells.
The Biochemical journal 1992;285 ( Pt 3)():759-66.
1992: Asif Ahmed; R A Ferriani; Robin Plevin; Stephen K Smith
Platelet-activating factor mediates phosphatidylcholine hydrolysis by phospholipase D in human endometrium.
Biology of reproduction 1992;47(1):59-65.
1991: Robin Plevin; E E MacNulty; S Palmer; Michael J O Wakelam
Differences in the regulation of endothelin-1- and lysophosphatidic-acid-stimulated Ins(1,4,5)P3 formation in rat-1 fibroblasts.
The Biochemical journal 1991;280 ( Pt 3)():609-15.
1991: Robin Plevin; S J Cook; S Palmer; Michael J O Wakelam
Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Evidence for activation of phosphoinositidase C and phosphatidylcholine-specific phospholipase D.
The Biochemical journal 1991;279 ( Pt 2)():559-65.
1991: S Palmer; Robin Plevin; Michael J O Wakelam
Homologous desensitization of bombesin-stimulated Ins(1,4,5)P3 production in Swiss 3T3 fibroblasts.
Biochemical Society transactions 1991;19(2):101S.
1991: Robin Plevin; E E MacNulty; S Palmer; Michael J O Wakelam
Differences in the coupling of ET-1 and LPA receptors in Ins(1,4,5)P3 formation in Rat-1 fibroblasts.
Biochemical Society transactions 1991;19(2):100S.
1990: E E MacNulty; Robin Plevin; Michael J O Wakelam
Stimulation of the hydrolysis of phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine by endothelin, a complete mitogen for Rat-1 fibroblasts.
The Biochemical journal 1990;272(3):761-6.
1990: Robin Plevin; S Palmer; S D Gardner; Michael J O Wakelam
Regulation of bombesin-stimulated inositol 1,4,5-trisphosphate generation in Swiss 3T3 fibroblasts by a guanine-nucleotide-binding protein.
The Biochemical journal 1990;268(3):605-10.
1990: S J Cook; Robin Plevin; S Palmer; Michael J O Wakelam
Bombesin and platelet-derived growth factor stimulate phosphatidylcholine breakdown by a common mechanism.
Biochemical Society transactions 1990;18(3):484-5.
1990: E E MacNulty; Robin Plevin; Michael J O Wakelam
Endothelin stimulates phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine hydrolysis in Rat-1 cells.
Biochemical Society transactions 1990;18(3):482-3.
1990: S J Cook; S Palmer; Robin Plevin; Michael J O Wakelam
Mass measurement of inositol 1,4,5-trisphosphate and sn-1,2-diacylglycerol in bombesin-stimulated Swiss 3T3 mouse fibroblasts.
The Biochemical journal 1990;265(2):617-20.
1988: Robin Plevin; B J Parsons; P Butcher; J A Poat
The possible involvement of changes in phosphoinositol turnover in the responses of renal sodium transport to noradrenaline.
Biochemical pharmacology 1988;37(11):2121-4.