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Karl Plössl

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Limin Wang; Zhihao Zha; Brian P Lieberman; Karl Plössl; Hongwen Qiao; Wenchao Qu; Hank F Kung
Synthesis and evaluation of 18F labeled alanine derivatives as potential tumor imaging agents.
Hongwen Qiao; Zhihao Zha; Lin Zhu; Brian P Lieberman; Karl Plössl; Hank F Kung
Synthesis and evaluation of novel tropane derivatives as potential PET imaging agents for the dopamine transporter.
Jingying Liu; Lin Zhu; Karl Plössl; Brian P Lieberman; Hank F Kung
Synthesis and evaluation of novel N-fluoropyridyl derivatives of tropane as potential PET imaging agents for the dopamine transporter.

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2012: Limin Wang; Zhihao Zha; Brian P Lieberman; Karl Plössl; Hongwen Qiao; Wenchao Qu; Hank F Kung
Synthesis and evaluation of 18F labeled alanine derivatives as potential tumor imaging agents.
Nuclear medicine and biology 2012;39(7):933-43.
2012: Hongwen Qiao; Zhihao Zha; Lin Zhu; Brian P Lieberman; Karl Plössl; Hank F Kung
Synthesis and evaluation of novel tropane derivatives as potential PET imaging agents for the dopamine transporter.
Bioorganic & medicinal chemistry letters 2012;22(13):4303-6.
2011: Jingying Liu; Lin Zhu; Karl Plössl; Brian P Lieberman; Hank F Kung
Synthesis and evaluation of novel N-fluoropyridyl derivatives of tropane as potential PET imaging agents for the dopamine transporter.
Bioorganic & medicinal chemistry letters 2011;21(10):2962-5.
2011: Limin Wang; Brian P Lieberman; Karl Plössl; Wenchao Qu; Hank F Kung
Synthesis and comparative biological evaluation of L- and D-isomers of 18F-labeled fluoroalkyl phenylalanine derivatives as tumor imaging agents.
Nuclear medicine and biology 2011;38(3):301-12.
2011: Limin Wang; Wenchao Qu; Brian P Lieberman; Karl Plössl; Hank F Kung
Synthesis, uptake mechanism characterization and biological evaluation of (18)F labeled fluoroalkyl phenylalanine analogs as potential PET imaging agents.
Nuclear medicine and biology 2011;38(1):53-62.
2010: Yajing Liu; Lin Zhu; Karl Plössl; Seok-Rye Choi; Hongwen Qiao; Xiaotao Sun; Song Li; Zhihao Zha; Hank F Kung
Optimization of automated radiosynthesis of [18F]AV-45: a new PET imaging agent for Alzheimer's disease.
Nuclear medicine and biology 2010;37(8):917-25.
2010: Lin Zhu; Yajing Liu; Karl Plössl; Brian Lieberman; Jingying Liu; Hank F Kung
An improved radiosynthesis of [18F]AV-133: a PET imaging agent for vesicular monoamine transporter 2.
Nuclear medicine and biology 2010;37(2):133-41.
2008: Karl Plössl; Rajesh Chandra; Wenchao Qu; Brian P Lieberman; Mei-Ping Kung; Rong Zhou; Bin Huang; Hank F Kung
A novel gallium bisaminothiolate complex as a myocardial perfusion imaging agent.
Nuclear medicine and biology 2008;35(1):83-90.
2006: Andrew B Newberg; Nancy Wintering; Karl Plössl; John Hochold; Michael G Stabin; Marianne Watson; Daniel M Skovronsky; Christopher M Clark; Mei-Ping Kung; Hank F Kung
Safety, biodistribution, and dosimetry of 123I-IMPY: a novel amyloid plaque-imaging agent for the diagnosis of Alzheimer's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(5):748-54.
2006: Paul D Acton; Andrew B Newberg; Karl Plössl; P David Mozley
Comparison of region-of-interest analysis and human observers in the diagnosis of Parkinson's disease using [99mTc]TRODAT-1 and SPECT.
Physics in medicine and biology 2006;51(3):575-85.
2004: Hank F Kung; Suzanne Newman; Seok-Rye Choi; Shunichi Oya; Catherine Hou; Zhi-Ping Zhuang; Paul D Acton; Karl Plössl; Jeffrey Winkler; Mei-Ping Kung
2-(2-(dimethylaminomethyl)phenoxy)-5-iodophenylamine: an improved serotonin transporter imaging agent.
Journal of medicinal chemistry 2004;47(21):5258-64.
2004: Andrew B Newberg; Karl Plössl; P David Mozley; James B Stubbs; Nancy Wintering; Michelle Udeshi; Abass Alavi; Tomi Kauppinen; Hank F Kung
Biodistribution and imaging with (123)I-ADAM: a serotonin transporter imaging agent.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(5):834-41.
2003: Hang F Kung; Mei-Ping Kung; Zhi-Ping Zhuang; Catherine Hou; Chi-Wan Lee; Karl Plössl; Bing Zhuang; Daniel M Skovronsky; Virginia M-Y Lee; John Q Trojanowski
Iodinated tracers for imaging amyloid plaques in the brain.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2003;5(6):418-26.
2003: Alberto Auricchio; Paul D Acton; Markus Hildinger; Jean-Pierre Louboutin; Karl Plössl; Erin O'Connor; Hank F Kung; James M Wilson
In vivo quantitative noninvasive imaging of gene transfer by single-photon emission computerized tomography.
Human gene therapy 2003;14(3):255-61.
2003: Zhi-Ping Zhuang; Mei-Ping Kung; Alan Wilson; Chi-Wan Lee; Karl Plössl; Catherine Hou; David M Holtzman; Hank F Kung
Structure-activity relationship of imidazo[1,2-a]pyridines as ligands for detecting beta-amyloid plaques in the brain.
Journal of medicinal chemistry 2003;46(2):237-43.
2002: Paul D Acton; Catherine Hou; Mei-Ping Kung; Karl Plössl; Cindy L Keeney; Hank F Kung
Occupancy of dopamine D2 receptors in the mouse brain measured using ultra-high-resolution single-photon emission tomography and [123]IBF.
European journal of nuclear medicine and molecular imaging 2002;29(11):1507-15.
2002: Paul D Acton; Seok-Rye Choi; Karl Plössl; Hank F Kung
Quantification of dopamine transporters in the mouse brain using ultra-high resolution single-photon emission tomography.
European journal of nuclear medicine and molecular imaging 2002;29(5):691-8.
2002: Paul D Acton; Mei-Ping Kung; Catherine Hou; Karl Plössl; Cindy Keeney; Hank F Kung
Ultra-high resolution single photon emission tomography imaging of the mouse striatum.
European journal of nuclear medicine and molecular imaging 2002;29(3):446.
2001: Hank F Kung; Chi-Wan Lee; Zhi-Ping Zhuang; Mei-Ping Kung; Catherine Hou; Karl Plössl
Novel stilbenes as probes for amyloid plaques.
Journal of the American Chemical Society 2001;123(50):12740-1.
2001: Zhi-Ping Zhuang; Mei-Ping Kung; Catherine Hou; Karl Plössl; Daniel M Skovronsky; Tamar L Gur; John Q Trojanowski; Virginia M-Y Lee; Hank F Kung
IBOX(2-(4'-dimethylaminophenyl)-6-iodobenzoxazole): a ligand for imaging amyloid plaques in the brain.
Nuclear medicine and biology 2001;28(8):887-94.
2001: Paul D Acton; Seok-Rye Choi; Catherine Hou; Karl Plössl; Hank F Kung
Quantification of serotonin transporters in nonhuman primates using [(123)I]ADAM and SPECT.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(10):1556-62.
2001: Seok-Rye Choi; B Yang; Karl Plössl; S Chumpradit; Shiaw-Pyng Wey; Paul D Acton; K Wheeler; R H Mach; Hank F Kung
Development of a Tc-99m labeled sigma-2 receptor-specific ligand as a potential breast tumor imaging agent.
Nuclear medicine and biology 2001;28(6):657-66.
2001: Chi-Wan Lee; Zhi-Ping Zhuang; Mei-Ping Kung; Karl Plössl; Daniel M Skovronsky; Tamar L Gur; Catherine Hou; John Q Trojanowski; Virginia M-Y Lee; Hank F Kung
Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene in strong base: probes for amyloid plaques in the brain.
Journal of medicinal chemistry 2001;44(14):2270-5.
2001: Zhi-Ping Zhuang; Mei-Ping Kung; Catherine Hou; Daniel M Skovronsky; Tamar L Gur; Karl Plössl; John Q Trojanowski; Virginia M-Y Lee; Hank F Kung
Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates.
Journal of medicinal chemistry 2001;44(12):1905-14.
2000: Paul D Acton; Philipp T Meyer; P David Mozley; Karl Plössl; Hank F Kung
Simplified quantification of dopamine transporters in humans using [99mTc]TRODAT-1 and single-photon emission tomography.
European journal of nuclear medicine 2000;27(11):1714-8.
2000: P David Mozley; Jay S Schneider; Paul D Acton; Karl Plössl; Matthew B Stern; Andrew Siderowf; N A Leopold; P Y Li; Abass Alavi; Hank F Kung
Binding of [99mTc]TRODAT-1 to dopamine transporters in patients with Parkinson's disease and in healthy volunteers.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2000;41(4):584-9.
1999: P David Mozley; Paul D Acton; ED Barraclough; Karl Plössl; Ruben C Gur; Abass Alavi; A Mathur; Janet R Saffer; Hank F Kung
Effects of age on dopamine transporters in healthy humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(11):1812-7.
1999: M Mu; Mei-Ping Kung; Karl Plössl; Paul D Acton; P David Mozley; Hank F Kung
A simplified method to determine [99mTc]TRODAT-1 in human plasma.
Nuclear medicine and biology 1999;26(7):821-5.
1999: Paul D Acton; M Mu; Karl Plössl; Catherine Hou; M Siciliano; Zhi-Ping Zhuang; Shunichi Oya; Seok-Rye Choi; Hank F Kung
Single-photon emission tomography imaging of serotonin transporters in the nonhuman primate brain with [(123)I]ODAM.
European journal of nuclear medicine 1999;26(10):1359-62.
1999: Paul D Acton; Mei-Ping Kung; M Mu; Karl Plössl; Catherine Hou; M Siciliano; Shunichi Oya; Hank F Kung
Single-photon emission tomography imaging of serotonin transporters in the non-human primate brain with the selective radioligand [(123)I]IDAM.
European journal of nuclear medicine 1999;26(8):854-61.
1999: Seok-Rye Choi; Mei-Ping Kung; Karl Plössl; SK Meegalla; Hank F Kung
An improved kit formulation of a dopamine transporter imaging agent: [Tc-99m]TRODAT-1.
Nuclear medicine and biology 1999;26(4):461-6.
1999: Paul D Acton; SA Kushner; Mei-Ping Kung; P David Mozley; Karl Plössl; Hank F Kung
Simplified reference region model for the kinetic analysis of [99mTc]TRODAT-1 binding to dopamine transporters in nonhuman primates using single-photon emission tomography.
European journal of nuclear medicine 1999;26(5):518-26.
1999: SH Dresel; Mei-Ping Kung; X F Huang; Karl Plössl; Catherine Hou; SK Meegalla; G Patselas; M Mu; Janet R Saffer; Hank F Kung
Simultaneous SPECT studies of pre- and postsynaptic dopamine binding sites in baboons.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(4):660-6.
1999: SH Dresel; Mei-Ping Kung; X Huang; Karl Plössl; Catherine Hou; Chyng-Yann Shiue; Jonathan Karp; Hank F Kung
In vivo imaging of serotonin transporters with [99mTc]TRODAT-1 in nonhuman primates.
European journal of nuclear medicine 1999;26(4):342-7.
1999: Zhi-Ping Zhuang; Karl Plössl; Mei-Ping Kung; M Mu; Hank F Kung
Neutral and stereospecific Tc-99m complexes: [99mTc]N-benzyl-3,4-di-(N-2-mercaptoethyl)-amino-pyrrolidines (P-BAT).
Nuclear medicine and biology 1999;26(2):217-24.
1999: SA Kushner; WT McElgin; Mei-Ping Kung; P David Mozley; Karl Plössl; SK Meegalla; M Mu; SH Dresel; JM Vessotskie; N Lexow; Hank F Kung
Kinetic modeling of [99mTc]TRODAT-1: a dopamine transporter imaging agent.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(1):150-8.
1998: P David Mozley; James B Stubbs; Karl Plössl; SH Dresel; ED Barraclough; Abass Alavi; Luis Araujo; Hank F Kung
Biodistribution and dosimetry of TRODAT-1: a technetium-99m tropane for imaging dopamine transporters.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(12):2069-76.
1998: SK Meegalla; Karl Plössl; Mei-Ping Kung; DA Stevenson; M Mu; SA Kushner; L M Liable-Sands; A L Rheingold; Hank F Kung
Specificity of diastereomers of [99mTc]TRODAT-1 as dopamine transporter imaging agents.
Journal of medicinal chemistry 1998;41(4):428-36.
1998: Shunichi Oya; Karl Plössl; Mei-Ping Kung; DA Stevenson; Hank F Kung
Small and neutral Tc(v)O BAT, bisaminoethanethiol (N2S2) complexes for developing new brain imaging agents.
Nuclear medicine and biology 1998;25(2):135-40.
1998: SH Dresel; Mei-Ping Kung; Karl Plössl; SK Meegalla; Hank F Kung
Pharmacological effects of dopaminergic drugs on in vivo binding of [99mTc]TRODAT-1 to the central dopamine transporters in rats.
European journal of nuclear medicine 1998;25(1):31-9.
1997: Mei-Ping Kung; DA Stevenson; Karl Plössl; SK Meegalla; A Beckwith; W D Essman; M Mu; I Lucki; Hank F Kung
[99mTc]TRODAT-1: a novel technetium-99m complex as a dopamine transporter imaging agent.
European journal of nuclear medicine 1997;24(4):372-80.
1997: SK Meegalla; Karl Plössl; Mei-Ping Kung; S Chumpradit; DA Stevenson; SA Kushner; WT McElgin; P David Mozley; Hank F Kung
Synthesis and characterization of technetium-99m-labeled tropanes as dopamine transporter-imaging agents.
Journal of medicinal chemistry 1997;40(1):9-17.
1996: Hank F Kung; H J Kim; Mei-Ping Kung; SK Meegalla; Karl Plössl; H K Lee
Imaging of dopamine transporters in humans with technetium-99m TRODAT-1.
European journal of nuclear medicine 1996;23(11):1527-30.
1996: SK Meegalla; Karl Plössl; Mei-Ping Kung; S Chumpradit; DA Stevenson; D Frederick; Hank F Kung
Tc-99m-labeled tropanes as dopamine transporter imaging agents.
Bioconjugate chemistry 1996;7(4):421-9.