Eckhard Podack

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Schreiber T H; Podack E R
A critical analysis of the tumour immunosurveillance controversy for 3-MCA-induced sarcomas.
Podack Eckhard R
How to polymerize in order to survive.
Schreiber Taylor H; Deyev Vadim V; Rosenblatt Joseph D; Podack Eckhard R
Tumor-induced suppression of CTL expansion and subjugation by gp96-Ig vaccination.

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All Publications

2009: Schreiber T H; Podack E R
A critical analysis of the tumour immunosurveillance controversy for 3-MCA-induced sarcomas.
British journal of cancer 2009;101(3):381-6.
2009: Podack Eckhard R
How to polymerize in order to survive.
Immunity 2009;30(5):668-70.
2009: Schreiber Taylor H; Deyev Vadim V; Rosenblatt Joseph D; Podack Eckhard R
Tumor-induced suppression of CTL expansion and subjugation by gp96-Ig vaccination.
Cancer research 2009;69(5):2026-33.
2008: Xiao Yanping; Motomura Seiichi; Podack Eckhard R
APRIL (TNFSF13) regulates collagen-induced arthritis, IL-17 production and Th2 response.
European journal of immunology 2008;38(12):3450-8.
2008: Tang Ce; Yamada Hisakata; Shibata Kensuke; Muta Hiromi; Wajjwalku Worawidh; Podack Eckhard R; Yoshikai Yasunobu
A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(9):6316-27.
2008: Fang Lei; Adkins Becky; Deyev Vadim; Podack Eckhard R
Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation.
The Journal of experimental medicine 2008;205(5):1037-48.
2008: Strbo Natasa; Podack Eckhard R
Secreted heat shock protein gp96-Ig: an innovative vaccine approach.
American journal of reproductive immunology (New York, N.Y. : 1989) 2008;59(5):407-16.
2008: Oizumi Satoshi; Deyev Vadim; Yamazaki Koichi; Schreiber Taylor; Strbo Natasa; Rosenblatt Joseph; Podack Eckhard R
Surmounting tumor-induced immune suppression by frequent vaccination or immunization in the absence of B cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(4):394-401.
2008: Sun Xun; Somada Shinichi; Shibata Kensuke; Muta Hiromi; Yamada Hisakata; Yoshihara Hirofumi; Honda Kuniomi; Nakamura Kazuhiko; Takayanagi Ryhoichi; Tani Kenzaburo; Podack Eckhard R; Yoshikai Yasunobu
A critical role of CD30 ligand/CD30 in controlling inflammatory bowel diseases in mice.
Gastroenterology 2008;134(2):447-58.
2008: Nam Sang-Yun; Kim Young-Hyun; Do Jeong-Su; Choi Yun-Hwa; Seo Hyo-Jung; Yi Ho-Keun; Hwang Pyung-Han; Song Chang-Ho; Lee Hern-Ku; Kim Jeong-Su; Podack Eckhard R
CD30 supports lung inflammation.
International immunology 2008;20(2):177-84.
2007: Podack Eckhard R; Raez Luis E
Allogeneic tumor-cell-based vaccines secreting endoplasmic reticulum chaperone gp96.
Expert opinion on biological therapy 2007;7(11):1679-88.
2007: Yi Kyung H; Nechushtan Hovav; Bowers William J; Walker Gail R; Zhang Yu; Pham Dien G; Podack Eckhard R; Federoff Howard J; Tolba Khaled A; Rosenblatt Joseph D
Adoptively transferred tumor-specific T cells stimulated ex vivo using herpes simplex virus amplicons encoding 4-1BBL persist in the host and show antitumor activity in vivo.
Cancer research 2007;67(20):10027-37.
2007: Oizumi Satoshi; Strbo Natasa; Pahwa Savita; Deyev Vadim; Podack Eckhard R
Molecular and cellular requirements for enhanced antigen cross-presentation to CD8 cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2310-7.
2007: Podack Eckhard R; Deyev Vadim; Shiratsuchi Motoaki
Pore formers of the immune system.
Advances in experimental medicine and biology 2007;598():325-41.
2006: Raez Luis E; Rosenblatt Joseph D; Podack Eckhard R
Present and future of lung cancer vaccines.
Expert opinion on emerging drugs 2006;11(3):445-59.
2006: Lee Kelvin P; Raez Luis E; Podack Eckhard R
Heat shock protein-based cancer vaccines.
Hematology/oncology clinics of North America 2006;20(3):637-59.
2006: Strbo Natasa; Laskarin Gordana; Bogovic Crncic Tatjana; Juretic Frankovic Koraljka; Bedenicki Ivica; Sotosek Tokmadzic Vlatka; Randic Ljiljana; Le Bouteiller Philippe; Tabiasco Julie; Podack Eckhard R; Rukavina Daniel
Short-term cytolytic mediators' expression in decidual lymphocytes is enhanced by interleukin-15.
American journal of reproductive immunology (New York, N.Y. : 1989) 2006;55(3):217-25.
2005: Raez Luis E; Fein Steven; Podack Eckhard R
Lung cancer immunotherapy.
Clinical medicine & research 2005;3(4):221-8.
2005: Nishimura Hitoshi; Yajima Toshiki; Muta Hiromi; Podack Eckhard R; Tani Kenzaburo; Yoshikai Yasunobu
A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4627-34.
2005: Raez Luis E; Santos Edgardo S; Mudad Raja; Podack Eckhard R
Clinical trials targeting lung cancer with active immunotherapy: the scope of vaccines.
Expert review of anticancer therapy 2005;5(4):635-44.
2005: Zimmerman Zachary; Shatry Alwi; Deyev Vadim; Podack Eckhard; Mammolenti Michele; Blazar Bruce R; Yagita Hideo; Levy Robert B
Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necrosis factor family effector pathways.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(8):576-86.
2004: Blazar Bruce R; Levy Robert B; Mak Tak W; Panoskaltsis-Mortari Angela; Muta Hiromi; Jones Monica; Roskos Melinda; Serody Jonathan S; Yagita Hideo; Podack Eckhard R; Taylor Patricia A
CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):2933-41.
2004: Raez Luis E; Cassileth Peter A; Schlesselman James J; Sridhar Kasi; Padmanabhan Swaminathan; Fisher Eva Z; Baldie Paulette A; Podack Eckhard R
Allogeneic vaccination with a B7.1 HLA-A gene-modified adenocarcinoma cell line in patients with advanced non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(14):2800-7.
2004: Marks Lianne; Altman Norman H; Podack Eckhard R; Levy Robert B
Donor T cells lacking Fas ligand and perforin retain the capacity to induce severe GvHD in minor histocompatibility antigen mismatched bone-marrow transplantation recipients.
Transplantation 2004;77(6):804-12.
2003: Raez Luis E; Cassileth Peter A; Schlesselman James J; Padmanabhan Swaminathan; Fisher Eva Z; Baldie Paulette A; Sridhar Kasi; Podack Eckhard R
Induction of CD8 T-cell-Ifn-gamma response and positive clinical outcome after immunization with gene-modified allogeneic tumor cells in advanced non-small-cell lung carcinoma.
Cancer gene therapy 2003;10(11):850-8.
2003: Dix Richard D; Podack Eckhard R; Cousins Scott W
Murine cytomegalovirus retinitis during retrovirus-induced immunodeficiency (MAIDS) in mice: interleukin-2 immunotherapy correlates with increased intraocular levels of perforin mRNA.
Antiviral research 2003;59(2):111-9.
2003: Gulan Gordan; Ravlic-Gulan Jagoda; Strbo Natasa; Sotosek Vlatka; Nemec Boris; Matovinovic Damir; Rubinic Dusan; Podack Eckhard R; Rukavina Daniel
Systemic and local expression of perforin in lymphocyte subsets in acute and chronic rheumatoid arthritis.
The Journal of rheumatology 2003;30(4):660-70.
2003: Strbo Natasa; Oizumi Satoshi; Sotosek-Tokmadzic Vlatka; Podack Eckhard R
Perforin is required for innate and adaptive immunity induced by heat shock protein gp96.
Immunity 2003;18(3):381-90.
2003: Dix Richard D; Podack Eckhard R; Cousins Scott W
Loss of the perforin cytotoxic pathway predisposes mice to experimental cytomegalovirus retinitis.
Journal of virology 2003;77(6):3402-8.
2003: Dai Jie; Liu Bei; Caudill Marissa M; Zheng Hong; Qiao Yi; Podack Ekhard R; Li Zihai
Cell surface expression of heat shock protein gp96 enhances cross-presentation of cellular antigens and the generation of tumor-specific T cell memory.
Cancer immunity : a journal of the Academy of Cancer Immunology 2003;3():1.
2002: Podack Eckhard R; Strbo Natasa; Sotosec Vlatka; Muta Hiromi
CD30-governor of memory T cells?
Annals of the New York Academy of Sciences 2002;975():101-13.
2002: Strbo Natasa; Yamazaki Koichi; Lee Kelvin; Rukavina Daniel; Podack Eckhard R
Heat shock fusion protein gp96-Ig mediates strong CD8 CTL expansion in vivo.
American journal of reproductive immunology (New York, N.Y. : 1989) 2002;48(4):220-5.
2002: Laskarin Gordana; Tokmadzic Vlatka S; Strbo Natasa; Bogovic Tatjana; Szekeres-Bartho Julia; Randic Ljiljana; Podack Eckhard R; Rukavina Daniel
Progesterone induced blocking factor (PIBF) mediates progesterone induced suppression of decidual lymphocyte cytotoxicity.
American journal of reproductive immunology (New York, N.Y. : 1989) 2002;48(4):201-9.
2002: Tokmadzic Vlatka S; Tsuji Yoshiyuki; Bogovic Tatjana; Laskarin Gordana; Cupurdija Kristijan; Strbo Natasa; Koyama Koji; Okamura Haruki; Podack Eckhard R; Rukavina Daniel
IL-18 is present at the maternal-fetal interface and enhances cytotoxic activity of decidual lymphocytes.
American journal of reproductive immunology (New York, N.Y. : 1989) 2002;48(4):191-200.
2002: Pár Gabriella; Rukavina Daniel; Podack Eckhard R; Horányi Margit; Szekeres-Barthó Júlia; Hegedüs Géza; Paál Mária; Szereday László; Mózsik Gyula; Pár Alajos
Decrease in CD3-negative-CD8dim(+) and Vdelta2/Vgamma9 TcR+ peripheral blood lymphocyte counts, low perforin expression and the impairment of natural killer cell activity is associated with chronic hepatitis C virus infection.
Journal of hepatology 2002;37(4):514-22.
2002: Nam Sang Yun; Cho Kyong Shin; Heo Young Moon; Ha Jong Cheon; Kim Young Hyun; Keun Yi Ho; Han Hwang Pyong; Kim Hyung Min; Podack Eckhard R
Regulation of lymphocyte clustering by CD30-mediated ICAM-1 up-regulation.
Cellular immunology 2002;219(1):38-47.
2002: Harlin Helena; Podack Eckhard; Boothby Mark; Alegre Maria-Luisa
TCR-independent CD30 signaling selectively induces IL-13 production via a TNF receptor-associated factor/p38 mitogen-activated protein kinase-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(5):2451-9.
2002: Merger M; Viney J L; Borojevic R; Steele-Norwood D; Zhou P; Clark D A; Riddell R; Maric R; Podack E R; Croitoru K
Defining the roles of perforin, Fas/FasL, and tumour necrosis factor alpha in T cell induced mucosal damage in the mouse intestine.
Gut 2002;51(2):155-63.
2002: Kawasaki C; Ohshima K; Muta H; Muta K; Deyev V; Podack E R; Kikuchi M
Prognostic value of Bcl 10 rearrangement in diffuse large B-cell lymphoma.
Leukemia & lymphoma 2002;43(4):823-6.
2002: Metkar Sunil S; Wang Baikun; Aguilar-Santelises Miguel; Raja Srikumar M; Uhlin-Hansen Lars; Podack Eckhard; Trapani Joseph A; Froelich Christopher J
Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.
Immunity 2002;16(3):417-28.
2001: Toomey N L; Deyev V V; Wood C; Boise L H; Scott D; Liu L H; Cabral L; Podack E R; Barber G N; Harrington W J
Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma.
Oncogene 2001;20(48):7029-40.
2001: Ohshima K; Kawasaki C; Muta H; Muta K; Deyev V; Haraoka S; Suzumiya J; Podack E R; Kikuchi M
CD10 and Bcl10 expression in diffuse large B-cell lymphoma: CD10 is a marker of improved prognosis.
Histopathology 2001;39(2):156-62.
2001: Ohshima K; Muta H; Kawasaki C; Muta K; Deyev V; Kanda M; Kumano Y; Podack E R; Kikuchi M
Bcl10 expression, rearrangement and mutation in MALT lymphoma: correlation with expression of nuclear factor-kappaB.
International journal of oncology 2001;19(2):283-9.
2001: Jiang Z; Podack E; Levy R B
Major histocompatibility complex-mismatched allogeneic bone marrow transplantation using perforin and/or Fas ligand double-defective CD4(+) donor T cells: involvement of cytotoxic function by donor lymphocytes prior to graft-versus-host disease pathogenesis.
Blood 2001;98(2):390-7.
2001: Hnatyszyn H J; Podack E R; Young A K; Seivright R; Spruill G; Kraus G
The use of real-time PCR and fluorogenic probes for rapid and accurate genotyping of newborn mice.
Molecular and cellular probes 2001;15(3):169-75.
2000: Muta H; Boise L H; Fang L; Podack E R
CD30 signals integrate expression of cytotoxic effector molecules, lymphocyte trafficking signals, and signals for proliferation and apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5105-11.
2000: Rukavina D; Podack E R
Abundant perforin expression at the maternal-fetal interface: guarding the semiallogeneic transplant?
Immunology today 2000;21(4):160-3.
2000: Prpic L; Strbo N; Sotosek V; Gruber F; Podack E R; Rukavina D
Assessment of perforin expression in peripheral blood lymphocytes in psoriatic patients during exacerbation of disease.
Acta dermato-venereologica. Supplementum 2000;(211):14-6.
1999: Laskarin G; Strbo N; Sotosek V; Rukavina D; Faust Z; Szekeres-Bartho J; Podack E R
Progesterone directly and indirectly affects perforin expression in cytolytic cells.
American journal of reproductive immunology (New York, N.Y. : 1989) 1999;42(5):312-20.
1999: Lee R K; Cai J P; Deyev V; Gill P S; Cabral L; Wood C; Agarwal R P; Xia W; Boise L H; Podack E; Harrington W J
Azidothymidine and interferon-alpha induce apoptosis in herpesvirus-associated lymphomas.
Cancer research 1999;59(21):5514-20.
1999: Yamazaki K; Nguyen T; Podack E R
Cutting edge: tumor secreted heat shock-fusion protein elicits CD8 cells for rejection.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5178-82.
1999: Yamazaki K; Spruill G; Rhoderick J; Spielman J; Savaraj N; Podack E R
Small cell lung carcinomas express shared and private tumor antigens presented by HLA-A1 or HLA-A2.
Cancer research 1999;59(18):4642-50.
1999: Schoell W M; Mirhashemi R; Liu B; Janicek M F; Podack E R; Penalver M A; Averette H E
Generation of tumor-specific cytotoxic T lymphocytes by stimulation with HPV type 16 E7 peptide-pulsed dendritic cells: an approach to immunotherapy of cervical cancer.
Gynecologic oncology 1999;74(3):448-55.
1999: Sotosek V; Laskarin G; Strbo N; Dohr G; Blaschitz A; Podack E R; Rukavina D
Decidual macrophages are the population of decidual adherent cells which regulates perforin expression in cytolytic cells.
American journal of reproductive immunology (New York, N.Y. : 1989) 1999;42(2):76-82.
1999: Petito C K; Kerza-Kwiatecki A P; Gendelman H E; McCarthy M; Nath A; Podack E R; Shapshak P; Wiley C A
Review: neuronal injury in HIV infection.
Journal of neurovirology 1999;5(4):327-41.
1999: Strbo N; Laskarin G; Sotosek V; Randic L J; Podack E R; Rukavina D
Modulation of perforin expression in the decidual and peripheral blood cytotoxic lymphocytes in culture.
American journal of reproductive immunology (New York, N.Y. : 1989) 1999;42(1):14-21.
1999: Podack E R
How to induce involuntary suicide: the need for dipeptidyl peptidase I.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8312-4.
1999: Chiarle R; Podda A; Prolla G; Podack E R; Thorbecke G J; Inghirami G
CD30 overexpression enhances negative selection in the thymus and mediates programmed cell death via a Bcl-2-sensitive pathway.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):194-205.
1998: Spielman J; Lee R K; Podack E R
Perforin/Fas-ligand double deficiency is associated with macrophage expansion and severe pancreatitis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):7063-70.
1998: Simpson S J; De Jong Y P; Shah S A; Comiskey M; Wang B; Spielman J A; Podack E R; Mizoguchi E; Bhan A K; Terhorst C
Consequences of Fas-ligand and perforin expression by colon T cells in a mouse model of inflammatory bowel disease.
Gastroenterology 1998;115(4):849-55.
1998: Rukavina D; Laskarin G; Rubesa G; Strbo N; Bedenicki I; Manestar D; Glavas M; Christmas S E; Podack E R
Age-related decline of perforin expression in human cytotoxic T lymphocytes and natural killer cells.
Blood 1998;92(7):2410-20.
1998: Du Z; Ricordi C; Inverardi L; Podack E; Pastori R L
Efficient ex vivo inhibition of perforin and Fas ligand expression by chimeric tRNA-hammerhead ribozymes.
Human gene therapy 1998;9(11):1551-60.
1998: Bennett M; Taylor P A; Austin M; Baker M B; Schook L B; Rutherford M; Kumar V; Podack E R; Mohler K M; Levy R B; Blazar B R
Cytokine and cytotoxic pathways of NK cell rejection of class I-deficient bone marrow grafts: influence of mouse colony environment.
International immunology 1998;10(6):785-90.
1998: Gilfillan M C; Noel P J; Podack E R; Reiner S L; Thompson C B
Expression of the costimulatory receptor CD30 is regulated by both CD28 and cytokines.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(5):2180-7.
1997: Telford W G; Nam S Y; Podack E R; Miller R A
CD30-regulated apoptosis in murine CD8 T cells after cessation of TCR signals.
Cellular immunology 1997;182(2):125-36.
1997: Uno T; Chen P W; Murray T G; Podack E R; Ksander B R
Gene transfer of the CD80 costimulatory molecule into ocular melanoma cells using a novel episomal vector.
Investigative ophthalmology & visual science 1997;38(12):2531-9.
1997: Rukavina D; Podack E R; Rubesa G; Spanjol-Pandelo S; Randic L
Down-regulated expression of perforin-positive/CD16+ cells in the peripheral blood lymphocytes in the first trimester of pregnancy and up-regulation at the end of pregnancy.
American journal of reproductive immunology (New York, N.Y. : 1989) 1997;38(3):189-96.
1997: Gudelj L; Christmas S E; Laskarin G; Johnson P M; Podack E R; Rukavina D
Membrane phenotype and expression of perforin and serine esterases by CD3- peripheral blood and decidual granular lymphocyte-derived clones.
American journal of reproductive immunology (New York, N.Y. : 1989) 1997;38(3):162-7.
1997: Gulan G; Podack E R; Rukavina D; Gudelj L; Rubesa G; Petrovic O; Johnson P M; Christmas S E
Perforin-expressing lymphocytes in peripheral blood and decidua of human first-trimester pathological pregnancies.
American journal of reproductive immunology (New York, N.Y. : 1989) 1997;38(1):9-18.
1997: Du Z; Ricordi C; Podack E; Pastori R L
In vitro characterization of hammerhead ribozymes against perforin and fas-ligand RNA.
Transplantation proceedings 1997;29(4):2224-5.
1997: Selvaggi G; Ricordi C; Podack E; Inverardi L
Mechanisms of rejection of nonvascularized grafts: the role of perforin and Fas.
Transplantation proceedings 1997;29(4):2075-6.
1997: Stohl W; Elliott J E; Li L; Podack E R; Lynch D H; Jacob C O
Impaired nonrestricted cytolytic activity in systemic lupus erythematosus: involvement of a pathway independent of Fas, tumor necrosis factor, and extracellular ATP that is associated with little detectable perforin.
Arthritis and rheumatism 1997;40(6):1130-7.
1997: Ivanov V N; Lee R K; Podack E R; Malek T R
Regulation of Fas-dependent activation-induced T cell apoptosis by cAMP signaling: a potential role for transcription factor NF-kappa B.
Oncogene 1997;14(20):2455-64.
1997: Rubesa G; Podack E R; Sepcic J; Rukavina D
Increased perforin expression in multiple sclerosis patients during exacerbation of disease in peripheral blood lymphocytes.
Journal of neuroimmunology 1997;74(1-2):198-204.
1997: Nakamura T; Lee R K; Nam S Y; Podack E R; Bottomly K; Flavell R A
Roles of IL-4 and IFN-gamma in stabilizing the T helper cell type 1 and 2 phenotype.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(6):2648-53.
1997: Nakamura T; Lee R K; Nam S Y; Al-Ramadi B K; Koni P A; Bottomly K; Podack E R; Flavell R A
Reciprocal regulation of CD30 expression on CD4+ T cells by IL-4 and IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2090-8.
1997: Baker M B; Riley R L; Podack E R; Levy R B
Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1366-71.
1997: Pericle F; Epling-Burnette P K; Podack E R; Wei S; Djeu J Y
CD40-CD40L interactions provide "third-party" costimulation for T cell response against B7-1-transfected human breast tumor cells.
Journal of leukocyte biology 1997;61(2):201-8.
1996: Selvaggi G; Ricordi C; Podack E R; Inverardi L
The role of the perforin and Fas pathways of cytotoxicity in skin graft rejection.
Transplantation 1996;62(12):1912-5.
1996: Nishio M; Spielman J; Lee R K; Nelson D L; Podack E R
CD80 (B7.1) and CD54 (intracellular adhesion molecule-1) induce target cell susceptibility to promiscuous cytotoxic T cell lysis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4347-53.
1996: Chen P W; Geer D C; Podack E R; Ksander B R
Tumor cells transfected with B7-1 and interleukin-12 cDNA induce protective immunity.
Annals of the New York Academy of Sciences 1996;795():325-7.
1996: Du Z; Ricordi C; Podack E; Pastori R L
A hammerhead ribozyme that cleaves perforin and fas-ligand RNAs in vitro.
Biochemical and biophysical research communications 1996;226(3):595-600.
1996: Nishio M; Podack E R
Rapid induction of tumor necrosis factor cytotoxicity in naive splenic T cells by simultaneous CD80 (B7.1) and CD54 (ICAM-1) co-stimulation.
European journal of immunology 1996;26(9):2160-4.
1996: Lee R K; Spielman J; Zhao D Y; Olsen K J; Podack E R
Perforin, Fas ligand, and tumor necrosis factor are the major cytotoxic molecules used by lymphokine-activated killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(5):1919-25.
1996: Lee R K; Spielman J; Podack E R
Bcl-2 protects against Fas-based but not perforin-based T cell-mediated cytolysis.
International immunology 1996;8(7):991-1000.
1996: Baker M B; Altman N H; Podack E R; Levy R B
The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice.
The Journal of experimental medicine 1996;183(6):2645-56.
1996: Hameed A; Podack E R; Fox W M; Schafer R W; Sherman M E
Detection of perforin in human peritoneal fluid T-lymphocytes.
Acta cytologica 1996;40(3):401-7.
1996: Liu B; Podack E R; Allison J P; Malek T R
Generation of primary tumor-specific CTL in vitro to immunogenic and poorly immunogenic mouse tumors.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1117-25.
1996: Rukavina D; Balen-Marunic S; Rubesa G; Orlic P; Vujaklija K; Podack E R
Perforin expression in peripheral blood lymphocytes in rejecting and tolerant kidney transplant recipients.
Transplantation 1996;61(2):285-91.
1996: Bowen M A; Lee R K; Miragliotta G; Nam S Y; Podack E R
Structure and expression of murine CD30 and its role in cytokine production.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):442-9.
1995: Baker M B; Podack E R; Levy R B
Perforin- and Fas-mediated cytotoxic pathways are not required for allogeneic resistance to bone marrow grafts in mice.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1995;1(2):69-73.
1995: Baker M; Podack E R; Levy R B
Fas and perforin cytotoxic pathways are not the major effector mechanisms in allogeneic resistance to bone marrow.
Annals of the New York Academy of Sciences 1995;770():368-9.
1995: Levy R B; Baker M; Podack E R
Perforin-deficient T cells can induce acute graft-versus-host disease after transplantation of MHC-matched or MHC disparate allogeneic bone marrow.
Annals of the New York Academy of Sciences 1995;770():366-7.
1995: Selvaggi G; Inverardi L; Levy R B; Brendel M D; Spielman J; Mintz D H; Podack E R; Ricordi C
Abrogation of graft-versus-host disease following allotransplantation of cytotoxically deficient bone marrow across major histocompatibility barriers.
Annals of the New York Academy of Sciences 1995;770():339-44.
1995: Selvaggi G; Inverardi L; Levy R B; Mintz D H; Podack E R; Ricordi C
Tolerance induction to islet allografts following infusion of perforin deficient bone marrow.
Transplantation proceedings 1995;27(6):3193.
1995: Ivanov V N; Deng G; Podack E R; Malek T R
Pleiotropic effects of Bcl-2 on transcription factors in T cells: potential role of NF-kappa B p50-p50 for the anti-apoptotic function of Bcl-2.
International immunology 1995;7(11):1709-20.
1995: Deng G; Podack E R
Deoxyribonuclease induction in apoptotic cytotoxic T lymphocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(8):665-9.
1995: Rukavina D; Rubesa G; Gudelj L; Haller H; Podack E R
Characteristics of perforin expressing lymphocytes within the first trimester decidua of human pregnancy.
American journal of reproductive immunology (New York, N.Y. : 1989) 1995;33(5):394-404.
1995: Hameed A; Fox W M; Kurman R J; Hruban R H; Podack E R
Perforin expression in human cell-mediated luteolysis.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 1995;14(2):151-7.
1995: Hameed A; Fox W M; Kurman R J; Hruban R H; Podack E R
Perforin expression in endometrium during the menstrual cycle.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 1995;14(2):143-50.
1995: Isaaz S; Baetz K; Olsen K; Podack E; Griffiths G M
Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway.
European journal of immunology 1995;25(4):1071-9.
1995: Podack E R
Functional significance of two cytolytic pathways of cytotoxic T lymphocytes.
Journal of leukocyte biology 1995;57(4):548-52.
1995: Lichtenheld M G; Podack E R; Levy R B
Transgenic control of perforin gene expression. Functional evidence for two separate control regions.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(5):2153-63.
1995: Cassileth P A; Podack E; Sridhar K; Savaraj N; Hanlon J
Phase I study of transfected cancer cells expressing the interleukin-2 gene product in limited stage small cell lung cancer.
Human gene therapy 1995;6(3):369-83.
1995: Ohe Y; Zhao D; Saijo N; Podack E R
Construction of a novel bovine papillomavirus vector without detectable transforming activity suitable for gene transfer.
Human gene therapy 1995;6(3):325-33.
1995: Konjevic G; Schlesinger B; Cheng L; Olsen K J; Podack E R; Spuzic I
Analysis of perforin expression in human peripheral blood lymphocytes, CD56+ natural killer cell subsets and its induction by interleukin-2.
Immunological investigations 1995;24(3):499-507.
1995: Podack E R
Execution and suicide: cytotoxic lymphocytes enforce Draconian laws through separate molecular pathways.
Current opinion in immunology 1995;7(1):11-6.
1995: Podack E R
Perforin, killer cells and gene transfer immunotherapy for cancer.
Current topics in microbiology and immunology 1995;198():121-30.
1994: Wu Z; Podack E R; McKenzie J M; Olsen K J; Zakarija M
Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease.
Clinical and experimental immunology 1994;98(3):470-7.
1994: Miskovsky E P; Liu A Y; Pavlat W; Viveen R; Stanhope P E; Finzi D; Fox W M; Hruban R H; Podack E R; Siliciano R F
Studies of the mechanism of cytolysis by HIV-1-specific CD4+ human CTL clones induced by candidate AIDS vaccines.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(6):2787-99.
1994: Ohira T; Ohe Y; Heike Y; Podack E R; Olsen K J; Nishio K; Nishio M; Miyahara Y; Funayama Y; Ogasawara H
Gene therapy for Lewis lung carcinoma with tumor necrosis factor and interleukin 2 cDNAs co-transfected subline.
Gene therapy 1994;1(4):269-75.
1994: Kägi D; Ledermann B; Bürki K; Seiler P; Odermatt B; Olsen K J; Podack E R; Zinkernagel R M; Hengartner H
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice.
Nature 1994;369(6475):31-7.
1994: Lopez-Cepero M; Garcia-Sanz J A; Herbert L; Riley R; Handel M E; Podack E R; Lopez D M
Soluble and membrane-bound TNF-alpha are involved in the cytotoxic activity of B cells from tumor-bearing mice against tumor targets.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(7):3333-41.
1994: Ohira T; Ohe Y; Heike Y; Podack E R; Olsen K J; Nishio K; Nishio M; Miyahara Y; Funayama Y; Ogasawara H
In vitro and in vivo growth of B16F10 melanoma cells transfected with interleukin-4 cDNA and gene therapy with the transfectant.
Journal of cancer research and clinical oncology 1994;120(11):631-5.
1993: Bowen M A; Olsen K J; Cheng L; Avila D; Podack E R
Functional effects of CD30 on a large granular lymphoma cell line, YT. Inhibition of cytotoxicity, regulation of CD28 and IL-2R, and induction of homotypic aggregation.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(11):5896-906.
1993: García-Sanz J A; Podack E R
Regulation of perforin gene expression in a T cell hybrid with inducible cytolytic activity.
European journal of immunology 1993;23(8):1877-83.
1993: Ohe Y; Podack E R; Olsen K J; Miyahara Y; Miura K; Saito H; Koishihara Y; Ohsugi Y; Ohira T; Nishio K
Interleukin-6 cDNA transfected Lewis lung carcinoma cells show unaltered net tumour growth rate but cause weight loss and shortened survival in syngeneic mice.
British journal of cancer 1993;67(5):939-44.
1993: Ohmori T; Podack E R; Nishio K; Takahashi M; Miyahara Y; Takeda Y; Kubota N; Funayama Y; Ogasawara H; Ohira T
Apoptosis of lung cancer cells caused by some anti-cancer agents (MMC, CPT-11, ADM) is inhibited by bcl-2.
Biochemical and biophysical research communications 1993;192(1):30-6.
1993: Deng G; Podack E R
Suppression of apoptosis in a cytotoxic T-cell line by interleukin 2-mediated gene transcription and deregulated expression of the protooncogene bcl-2.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2189-93.
1993: Ohe Y; Podack E R; Olsen K J; Miyahara Y; Ohira T; Miura K; Nishio K; Saijo N
Combination effect of vaccination with IL2 and IL4 cDNA transfected cells on the induction of a therapeutic immune response against Lewis lung carcinoma cells.
International journal of cancer. Journal international du cancer 1993;53(3):432-7.
1992: Lichtenheld M G; Podack E R
Structure and function of the murine perforin promoter and upstream region. Reciprocal gene activation or silencing in perforin positive and negative cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(8):2619-26.
1992: Keane R W; Tallent M W; Podack E R
Resistance and susceptibility of neural cells to lysis by cytotoxic lymphocytes and by cytolytic granules.
Transplantation 1992;54(3):520-6.
1992: Lu P; Garcia-Sanz J A; Lichtenheld M G; Podack E R
Perforin expression in human peripheral blood mononuclear cells. Definition of an IL-2-independent pathway of perforin induction in CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(11):3354-60.
1992: Hameed A; Olsen K J; Cheng L; Fox W M; Hruban R H; Podack E R
Immunohistochemical identification of cytotoxic lymphocytes using human perforin monoclonal antibody.
The American journal of pathology 1992;140(5):1025-30.
1992: Nelson P J; Geller R L; Podack E; Bach F H
Molecular events in late stages of T-cell functional maturation.
Scandinavian journal of immunology 1992;35(3):311-20.
1992: Podack E R
Perforin: structure, function, and regulation.
Current topics in microbiology and immunology 1992;178():175-84.
1991: Clément M V; Haddad P; Soulié A; Benvenuti C; Lichtenheld M G; Podack E R; Sigaux N; Sasportes M
Perforin and granzyme B as markers for acute rejection in heart transplantation.
International immunology 1991;3(11):1175-81.
1991: Podack E R; Hengartner H; Lichtenheld M G
A central role of perforin in cytolysis?
Annual review of immunology 1991;9():129-57.
1991: Podack E R; Kupfer A
T-cell effector functions: mechanisms for delivery of cytotoxicity and help.
Annual review of cell biology 1991;7():479-504.
1990: Meri S; Morgan B P; Wing M; Jones J; Davies A; Podack E; Lachmann P J
Human protectin (CD59), an 18-20-kD homologous complement restriction factor, does not restrict perforin-mediated lysis.
The Journal of experimental medicine 1990;172(1):367-70.
1990: Asch E; Podack E
Vitronectin binds to activated human platelets and plays a role in platelet aggregation.
The Journal of clinical investigation 1990;85(5):1372-8.
1989: Nagler-Anderson C; Lichtenheld M; Eisen H N; Podack E R
Perforin mRNA in primary peritoneal exudate cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(11):3440-3.
1989: Lichtenheld M G; Podack E R
Structure of the human perforin gene. A simple gene organization with interesting potential regulatory sequences.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(12):4267-74.
1989: Podack E R
Killer lymphocytes and how they kill.
Current opinion in cell biology 1989;1(5):929-33.
1989: Bach F H; Geller R L; Nelson P J; Panzer S; Gromo G; Benfield M R; Inverardi L; Podack E R; Witson J C; Houchins J P
A "minimal signal-stepwise activation" analysis of functional maturation of T lymphocytes.
Immunological reviews 1989;111():35-57.
1989: Müller C; Kägi D; Aebischer T; Odermatt B; Held W; Podack E R; Zinkernagel R M; Hengartner H
Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus.
European journal of immunology 1989;19(7):1253-9.
1989: Hameed A; Olsen K J; Lee M K; Lichtenheld M G; Podack E R
Cytolysis by Ca-permeable transmembrane channels. Pore formation causes extensive DNA degradation and cell lysis.
The Journal of experimental medicine 1989;169(3):765-77.
1989: Lowrey D M; Aebischer T; Olsen K; Lichtenheld M; Rupp F; Hengartner H; Podack E R
Cloning, analysis, and expression of murine perforin 1 cDNA, a component of cytolytic T-cell granules with homology to complement component C9.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(1):247-51.
1989: Preissner K P; Podack E R; Müller-Eberhard H J
SC5b-7, SC5b-8 and SC5b-9 complexes of complement: ultrastructure and localization of the S-protein (vitronectin) within the macromolecules.
European journal of immunology 1989;19(1):69-75.
1989: Hoffman M; Mittelman A; Dworkin B; Rosenthal W; Beneck D; Gafney E; Arlin Z; Levitt D; Podack E
Severe intrahepatic cholestasis in patients treated with recombinant interleukin-2 and lymphokine-activated killer cells.
Journal of cancer research and clinical oncology 1989;115(2):175-8.
1989: Podack E R; Hengartner H
Structure of perforin and its role in cytolysis.
The Year in immunology 1989;6():245-61.
1989: Podack E R; Olsen K J; Lowrey D M; Lichtenheld M
Structure and function of perforin.
Current topics in microbiology and immunology 1989;140():11-7.
1989: Podack E R
Granule-mediated cytolysis of target cells.
Current topics in microbiology and immunology 1989;140():1-9.
1989: Ascensao J L; Liu S J; Caro J; Podack E; Mittelman A; Zanjani E D; Zhao Y L
Erythropoiesis in cancer patients undergoing immunotherapy.
Advances in experimental medicine and biology 1989;271():197-204.
1988: Hameed A; Lowrey D M; Lichtenheld M; Podack E R
Characterization of three serine esterases isolated from human IL-2 activated killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(9):3142-7.
1988: Lichtenheld M G; Olsen K J; Lu P; Lowrey D M; Hameed A; Hengartner H; Podack E R
Structure and function of human perforin.
Nature 1988;335(6189):448-51.
1988: Lowrey D M; Hameed A; Lichtenheld M; Podack E R
Isolation and characterization of cytotoxic granules from human lymphokine (interleukin 2) activated killer cells.
Cancer research 1988;48(16):4681-8.
1988: Podack E R; Lowrey D M; Lichtenheld M; Olsen K J; Aebischer T; Binder D; Rupp F; Hengartner H
Structure, function and expression of murine and human perforin 1 (P1).
Immunological reviews 1988;103():203-11.
1988: Podack E R; Lowrey D M; Lichtenheld M; Hameed A
Function of granule perforin and esterases in T cell-mediated reactions. Components required for delivery of molecules to target cells.
Annals of the New York Academy of Sciences 1988;532():292-302.
1987: Koren H; Goldfarb R; Henkart P; Bleackley C; Bonavida B; Granger G; Palladino M; Podack E; Reynolds C; Ruddle N
Proposal for classification of leukocyte-associated cytolytic molecules: Denver, Colorado, September 28, 1986.
Journal of leukocyte biology 1987;41(5):447-9.
1987: Groscurth P; Qiao B Y; Podack E R; Hengartner H
Cellular localization of perforin 1 in murine cloned cytotoxic T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(9):2749-52.
1987: Lowrey D M; Rupp F; Aebischer T; Grey P; Hengartner H; Podack E R
Primary sequence homology between the effector molecules that mediate complement and T-lymphocyte cytotoxicity.
Annales de l'Institut Pasteur. Immunology 1987;138(2):296-300.
1987: Podack E R; Penichet K O; Lin B Y; Chiao J W; Mittelman A
Increased cytotoxicity and CD16 (Leu 11) expression in long-term, IL-2-activated human peripheral blood mononuclear cells.
Blood cells 1987;13(1-2):117-22.
1987: Liu S J; Ascensão J L; Podack E; Lin B Y; Arlin Z; Lutton J; Gafney E; Baskind P; Mittelman A
Cellular interactions in hemopoiesis.
Blood cells 1987;13(1-2):101-10.
1986: Young J D; Cohn Z A; Podack E R
The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities.
Science (New York, N.Y.) 1986;233(4760):184-90.
1986: Young J D; Podack E R; Cohn Z A
Properties of a purified pore-forming protein (perforin 1) isolated from H-2-restricted cytotoxic T cell granules.
The Journal of experimental medicine 1986;164(1):144-55.
1986: Podack E R; Dahlbäck B; Griffin J H
Interaction of S-protein of complement with thrombin and antithrombin III during coagulation. Protection of thrombin by S-protein from antithrombin III inactivation.
The Journal of biological chemistry 1986;261(16):7387-92.
1986: Young J D; Hengartner H; Podack E R; Cohn Z A
Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity.
Cell 1986;44(6):849-59.
1986: Young J D; Nathan C F; Podack E R; Palladino M A; Cohn Z A
Functional channel formation associated with cytotoxic T-cell granules.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(1):150-4.
1986: Podack E R
Molecular mechanisms of cytolysis by complement and by cytolytic lymphocytes.
Journal of cellular biochemistry 1986;30(2):133-70.
1985: Podack E R; Young J D; Cohn Z A
Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(24):8629-33.
1985: Pressner K T; Podack E R; Müller-Eberhard H J
Self-association of the seventh component of human complement (C7): dimerization and polymerization.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(1):452-8.
1985: Preissner K T; Podack E R; Müller-Eberhard H J
The membrane attack complex of complement: relation of C7 to the metastable membrane binding site of the intermediate complex C5b-7.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(1):445-51.
1985: Dahlbäck B; Podack E R
Characterization of human S protein, an inhibitor of the membrane attack complex of complement. Demonstration of a free reactive thiol group.
Biochemistry 1985;24(9):2368-74.
1985: Tschopp J; Podack E R; Müller-Eberhard H J
The membrane attack complex of complement: C5b-8 complex as accelerator of C9 polymerization.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(1):495-9.
1985: Podack E R; Konigsberg P J; Acha-Orbea H; Pircher H; Hengartner H
Cytolytic T-cell granules: biochemical properties and functional specificity.
Advances in experimental medicine and biology 1985;184():99-119.
1984: DiScipio R G; Gehring M R; Podack E R; Kan C C; Hugli T E; Fey G H
Nucleotide sequence of cDNA and derived amino acid sequence of human complement component C9.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(23):7298-302.
1984: Podack E R; Konigsberg P J
Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization.
The Journal of experimental medicine 1984;160(3):695-710.
1984: Podack E R
Molecular composition of the tubular structure of the membrane attack complex of complement.
The Journal of biological chemistry 1984;259(13):8641-7.
1984: Podack E R; Tschopp J
Membrane attack by complement.
Molecular immunology 1984;21(7):589-603.
1984: Tschopp J; Engel A; Podack E R
Molecular weight of poly(C9). 12 to 18 C9 molecules form the transmembrane channel of complement.
The Journal of biological chemistry 1984;259(3):1922-8.
1984: Podack E R; Preissner K T; Müller-Eberhard H J
Inhibition of C9 polymerization within the SC5b-9 complex of complement by S-protein.
Acta pathologica, microbiologica, et immunologica Scandinavica. Supplement 1984;284():89-96.
1983: Dennert G; Podack E R
Cytolysis by H-2-specific T killer cells. Assembly of tubular complexes on target membranes.
The Journal of experimental medicine 1983;157(5):1483-95.
1983: Vogel C W; Plückthun A; Podack E R; Dennis E A; Müller-Eberhard H J
The membrane attack complex of complement and its precursor proteins lack phospholipase activity.
Molecular immunology 1983;20(4):377-82.
1983: Podack E R; Dennert G
Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells.
Nature 1983;302(5907):442-5.
1982: Podack E R; Tschopp J
Circular polymerization of the ninth component of complement. Ring closure of the tubular complex confers resistance to detergent dissociation and to proteolytic degradation.
The Journal of biological chemistry 1982;257(24):15204-12.
1982: Tschopp J; Podack E R; Müller-Eberhard H J
Ultrastructure of the membrane attack complex of complement: detection of the tetramolecular C9-polymerizing complex C5b-8.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(23):7474-8.
1982: Harriman G R; Podack E R; Braude A I; Corbeil L C; Esser A F; Curd J G
Activation of complement by serum-resistant Neisseria gonorrhoeae. Assembly of the membrane attack complex without subsequent cell death.
The Journal of experimental medicine 1982;156(4):1235-49.
1982: Tschopp J; Müller-Eberhard H J; Podack E R
Formation of transmembrane tubules by spontaneous polymerization of the hydrophilic complement protein C9.
Nature 1982;298(5874):534-8.
1982: Podack E R; Tschoop J; Müller-Eberhard H J
Molecular organization of C9 within the membrane attack complex of complement. Induction of circular C9 polymerization by the C5b-8 assembly.
The Journal of experimental medicine 1982;156(1):268-82.
1982: Podack E R; Müller-Eberhard H J; Horst H; Hoppe W
Membrane attach complex of complement (MAC): three-dimensional analysis of MAC-phospholipid vesicle recombinants.
Journal of immunology (Baltimore, Md. : 1950) 1982;128(5):2353-7.
1982: Podack E R; Tschopp J
Polymerization of the ninth component of complement (C9): formation of poly(C9) with a tubular ultrastructure resembling the membrane attack complex of complement.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(2):574-8.
1981: Harriman G R; Esser A F; Podack E R; Wunderlich A C; Braude A I; Lint T F; Curd J G
The role of C9 in complement-mediated killing of Neisseria.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(6):2386-90.
1981: Hu V W; Esser A F; Podack E R; Wisnieski B J
The membrane attack mechanism of complement: photolabeling reveals insertion of terminal proteins into target membrane.
Journal of immunology (Baltimore, Md. : 1950) 1981;127(1):380-6.
1981: Podack E R; Stoffel W; Esser A F; Müller-Eberhard H J
Membrane attack complex of complement: distribution of subunits between the hydrocarbon phase of target membranes and water.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(7):4544-8.
1981: Tschopp J; Podack E R
Membranolysis by the ninth component of human complement.
Biochemical and biophysical research communications 1981;100(3):1409-14.
1981: Horn W; Opferkuch W; Podack E R
Suppression of the anti-erythrocyte immune response in mice by the C5b--9 complex of complement.
Immunology 1981;43(2):303-9.
1981: Podack E R; Müller-Eberhard H J
Membrane attack complex of complement. Evidence for its dimeric structure based on hybrid formation.
The Journal of biological chemistry 1981;256(7):3145-8.
1980: Podack E R; Müller-Eberhard H J
SC5b-9 complex of complement: formation of the dimeric membrane attack complex by removal of S-protein.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(4):1779-83.
1980: Podack E R; Esser A F; Biesecker G; Müller-Eberhard H J
Membrane attack complex of complement: a structural analysis of its assembly.
The Journal of experimental medicine 1980;151(2):301-13.
1980: Isenman D E; Podack E R; Cooper N R
The interaction of C5 with C3b in free solution: a sufficient condition for cleavage by a fluid phase C3/C5 convertase.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(1):326-31.
1980: Podack E R; Müller-Eberhard H J
Limited proteolysis of C5b-6: functional stability of the degraded complex.
Journal of immunology (Baltimore, Md. : 1950) 1980;124(1):332-6.
1979: Podack E R; Müller-Eberhard H J
Isolation of human S-protein, an inhibitor of the membrane attack complex of complement.
The Journal of biological chemistry 1979;254(19):9808-14.
1979: Podack E R; Kolb W P; Esser A F; Müller-Eberhard H J
Structural similarities between C6 and C7 of human complement.
Journal of immunology (Baltimore, Md. : 1950) 1979;123(3):1071-7.
1979: Bauer J; Podack E R; Valet G
Determination of the number of lytic sites in biconcave and spheroid erythrocyte ghosts after complement lysis.
Journal of immunology (Baltimore, Md. : 1950) 1979;122(5):2032-6.
1979: Kolb W P; Kolb L M; Podack E R
C1q: isolation from human serum in high yield by affinity chromatography and development of a highly sensitive hemolytic assay.
Journal of immunology (Baltimore, Md. : 1950) 1979;122(5):2103-11.
1979: Schreiber R D; Morrison D C; Podack E R; Müller-Eberhard H J
Bactericidal activity of the alternative complement pathway generated from 11 isolated plasma proteins.
The Journal of experimental medicine 1979;149(4):870-82.
1979: Esser A F; Kolb W P; Podack E R; Müller-Eberhard H J
Molecular reorganization of lipid bilayers by complement: a possible mechanism for membranolysis.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(3):1410-4.
1979: Biesecker G; Podack E R; Halverson C A; Müller-Eberhard H J
C5b-9 dimer: isolation from complement lysed cells and ultrastructural identification with complement-dependent membrane lesions.
The Journal of experimental medicine 1979;149(2):448-58.
1979: Podack E R; Biesecker G; Müller-Eberhard H J
Membrane attack complex of complement: generation of high-affinity phospholipid binding sites by fusion of five hydrophilic plasma proteins.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(2):897-901.
1979: Bartholomew R M; Podack E R; Esser A F
Quantitation of the membrane attack complex of complement in an air-driven ultracentrifuge.
Journal of immunological methods 1979;31(3-4):351-60.
1978: Podack E R; Müller-Eberhard H J
Binding of desoxycholate, phosphatidylcholine vesicles, lipoprotein and of the S-protein to complexes of terminal complement components.
Journal of immunology (Baltimore, Md. : 1950) 1978;121(3):1025-30.
1978: Podack E R; Biesecker G; Kolb W P; Müller-Eberhard H J
The C5b-6 complex: reaction with C7, C8, C9.
Journal of immunology (Baltimore, Md. : 1950) 1978;121(2):484-90.
1978: Podack E R; Kolb W P; Müller-Eberhard H J
The C5b-6 complex: formation, isolation, and inhibition of its activity by lipoprotein and the S-protein of human serum.
Journal of immunology (Baltimore, Md. : 1950) 1978;120(6):1841-8.
1977: Podack E R; Kolb W P; Müller-Eberhard H J
The SC5b-7 complex: formation, isolation, properties, and subunit composition.
Journal of immunology (Baltimore, Md. : 1950) 1977;119(6):2024-9.
1976: Podack E R; Kolb W P; Muller-Eberhard H J
The C5b-9 complex: subunit composition of the classical and alternative pathway-generated complex.
Journal of immunology (Baltimore, Md. : 1950) 1976;116(5):1431-4.
1976: Podack E R; Kolb W P; Müller-Eberhard H J
Purification of the sixth and seventh component of human complement without loss of hemolytic activity.
Journal of immunology (Baltimore, Md. : 1950) 1976;116(2):263-9.
1974: Podack E R; Saathoff G; Seubert
On the mechanism and control of the malonyl-CoA-dependent chain elongation of fatty acids. The malonyl-transfer reaction.
European journal of biochemistry / FEBS 1974;50(1):237-43.
1974: Seubert W; Podack E R; Saathoff G
Proceedings: Mechanism of microsomal chain elongation of fatty acids.
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1974;355(10):1255-6.
1974: Podack E R; Lakomek M; Saathoff G; Seubert W
On the mechanism and control of the malonyl-CoA-dependent chain elongation of fatty acids. Characterization of hexenoyl-CoA reductase from liver and adrenal cortex as a constituent of the microsomal chain elongation.
European journal of biochemistry / FEBS 1974;45(1):13-23.
1973: Seubert W; Podack E R
Mechanisms and physiological roles of fatty acid chain elongation in microsomes and mitochondria.
Molecular and cellular biochemistry 1973;1(1):29-40.
1972: Podack E R; Seubert W
[2,3-trans-Hexenoyl-CoA-reductase and 2,3-trans-decenoyl-CoA-reductase as components of microsomal, malonyl-CoA-dependent or mitochondrial acetyl CoA dependent chain prolongation of fatty acids]
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1972;353(10):1557.
1972: Podack E R; Seubert W
On the mechanism of malonyl-CoA independent fatty acid synthesis. II. Isolation, properties and subcellular location of trans-2,3-hexenoyl-CoA and trans-2,3-decenoyl-CoA reductase.
Biochimica et biophysica acta 1972;280(2):235-47.
1972: Podack E R; Seubert W
[Isolation, subcellular localization, properties and physiological significance of 2,3-trans-decenyl-CoA-reductase from rat liver]
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1972;353(5):744-5.

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