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Marcia Podlisny

Research Profile

Disorders

Alzheimer's Disease

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Anatomy

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Publications

TOP 3
Dominic M Walsh; Igor Klyubin; Ganesh M Shankar; Matthew Townsend; Julia V Fadeeva; V Betts; Marcia B Podlisny; James P Cleary; Karen K. Hsiao Ashe; Michael J Rowan; Dennis J Selkoe
The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.
Dominic M Walsh; Matthew Townsend; Marcia B Podlisny; Ganesh M Shankar; Julia V Fadeeva; Omar M A El-Agnaf; Dean Hartley; Dennis J Selkoe
Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation.
Dennis J Selkoe; Marcia B Podlisny
Deciphering the genetic basis of Alzheimer's disease.

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All Publications

2005: Dominic M Walsh; Igor Klyubin; Ganesh M Shankar; Matthew Townsend; Julia V Fadeeva; V Betts; Marcia B Podlisny; James P Cleary; Karen K. Hsiao Ashe; Michael J Rowan; Dennis J Selkoe
The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.
Biochemical Society transactions 2005;33(Pt 5):1087-90.
2005: Dominic M Walsh; Matthew Townsend; Marcia B Podlisny; Ganesh M Shankar; Julia V Fadeeva; Omar M A El-Agnaf; Dean Hartley; Dennis J Selkoe
Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(10):2455-62.
2002: Dennis J Selkoe; Marcia B Podlisny
Deciphering the genetic basis of Alzheimer's disease.
Annual review of genomics and human genetics 2002;3():67-99.
2000: Dominic M Walsh; B P Tseng; R E Rydel; Marcia B Podlisny; Dennis J Selkoe
The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain.
Biochemistry 2000;39(35):10831-9.
1998: Wei Qiao Qiu; Dominic M Walsh; Z Ye; K Vekrellis; Jimin Zhang; Marcia B Podlisny; Marsha Rich Rosner; A Safavi; Louis B Hersh; Dennis J Selkoe
Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation.
The Journal of biological chemistry 1998;273(49):32730-8.
1998: Marcia B Podlisny; Dominic M Walsh; P Amarante; Beth L Ostaszewski; Evelyn R Stimson; John E Maggio; David B Teplow; Dennis J Selkoe
Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.
Biochemistry 1998;37(11):3602-11.
1997: Weiming Xia; Jimin Zhang; Dora Kholodenko; Martin Citron; Marcia B Podlisny; David B Teplow; Christian Haass; Peter Seubert; Edward H Koo; Dennis J Selkoe
Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins.
The Journal of biological chemistry 1997;272(12):7977-82.
1997: Marcia B Podlisny; Martin Citron; P Amarante; R Sherrington; Weiming Xia; Jimin Zhang; Thekla S Diehl; Georges Levesque; Paul E Fraser; Christian Haass; Edward H Koo; Peter Seubert; Peter St George-Hyslop; David B Teplow; Dennis J Selkoe
Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.
Neurobiology of disease 1997;3(4):325-37.
1996: Jochen Walter; Anja Capell; J Grünberg; B Pesold; A Schindzielorz; R Prior; Marcia B Podlisny; Paul E Fraser; Peter St George-Hyslop; Dennis J Selkoe; Christian Haass
The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum.
Molecular medicine (Cambridge, Mass.) 1996;2(6):673-91.
1996: Dennis J Selkoe; T Yamazaki; Martin Citron; Marcia B Podlisny; Edward H Koo; David B Teplow; Christian Haass
The role of APP processing and trafficking pathways in the formation of amyloid beta-protein.
Annals of the New York Academy of Sciences 1996;777():57-64.
1995: Marcia B Podlisny; Beth L Ostaszewski; Sharon Squazzo; Edward H Koo; R E Rydell; David B Teplow; Dennis J Selkoe
Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture.
The Journal of biological chemistry 1995;270(16):9564-70.
1993: Marcia B Podlisny; DT Stephenson; M P Frosch; D R Tolan; I Lieberburg; JA Clemens; Dennis J Selkoe
Microinjection of synthetic amyloid beta-protein in monkey cerebral cortex fails to produce acute neurotoxicity.
The American journal of pathology 1993;142(1):17-24.
1992: Marcia B Podlisny; DT Stephenson; M P Frosch; I Lieberburg; JA Clemens; Dennis J Selkoe
Synthetic amyloid beta-protein fails to produce specific neurotoxicity in monkey cerebral cortex.
Neurobiology of aging 1992;13(5):561-7.
1991: Marcia B Podlisny; D R Tolan; Dennis J Selkoe
Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease.
The American journal of pathology 1991;138(6):1423-35.
1990: Marcia B Podlisny; ANDREW MAMMEN; Michael G Schlossmacher; M R Palmert; Steven G Younkin; Dennis J Selkoe
Detection of soluble forms of the beta-amyloid precursor protein in human plasma.
Biochemical and biophysical research communications 1990;167(3):1094-101.
1990: M R Palmert; Marcia B Podlisny; todd golde; M L Cohen; Dora M. Kovacs; Rudolph E Tanzi; James Gusella; Peter J Whitehouse; D S Witker; Tilman Oltersdorf
Analysis of the beta-amyloid protein precursor of Alzheimer's disease: mRNAs and protein products.
Advances in neurology 1990;51():181-4.
1990: Dennis J Selkoe; Marcia B Podlisny; A Gronbeck; ANDREW MAMMEN; Kenneth S Kosik
Molecular relation of amyloid filaments and paired helical filaments in Alzheimer's disease.
Advances in neurology 1990;51():171-9.
1989: M R Palmert; Sandra L Siedlak; Marcia B Podlisny; Barry D Greenberg; Earl R Shelton; H W Chan; M Usiak; Dennis J Selkoe; George Perry; Steven G Younkin
Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein.
Biochemical and biophysical research communications 1989;165(1):182-8.
1989: M R Palmert; Marcia B Podlisny; D S Witker; Tilman Oltersdorf; Linda Younkin; Dennis J Selkoe; Steven G Younkin
The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(16):6338-42.
1989: M R Palmert; Marcia B Podlisny; todd golde; M L Cohen; Dora M. Kovacs; Rudolph E Tanzi; James Gusella; Peter J Whitehouse; D S Witker; Tilman Oltersdorf
The beta amyloid protein precursor: mRNAs, membrane-associated forms, and soluble derivatives.
Progress in clinical and biological research 1989;317():971-84.
1988: M R Palmert; Marcia B Podlisny; D S Witker; Tilman Oltersdorf; Linda Younkin; Dennis J Selkoe; Steven G Younkin
Antisera to an amino-terminal peptide detect the amyloid protein precursor of Alzheimer's disease and recognize senile plaques.
Biochemical and biophysical research communications 1988;156(1):432-7.
1988: Dennis J Selkoe; Marcia B Podlisny; Catherine Joachim; E A Vickers; Gloria Lee; Lawrence C Fritz; Tilman Oltersdorf
Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(19):7341-5.
1987: Marcia B Podlisny; Gloria Lee; Dennis J Selkoe
Gene dosage of the amyloid beta precursor protein in Alzheimer's disease.
Science (New York, N.Y.) 1987;238(4827):669-71.