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Steven Pogwizd

Research Profile

Disorders

Living Beings

Rabbits

Anatomy

Chemicals & Drugs

Procedures

Body Surface Potential Mapping

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Phosphorylation

Physiology

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Publications

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Jonathan L Respress; Natale Rolim; Darlene G Skapura; Kristine Skårdal; Ralph J van Oort; Niels Voigt; Xun Ai; Angela deAlmeida; Sayali S Dixit; Dobromir Dobrev; William S Lawrence; Na Li; Steven M Pogwizd; Thomas Wieland; Ulrik Wisløff; Xander H T Wehrens
Role of RyR2 phosphorylation at S2814 during heart failure progression.
Carolyn M Johnson; Steven M Pogwizd
Focal initiation of sustained and nonsustained ventricular tachycardia in a canine model of ischemic cardiomyopathy.
Jose Osorio; Steven M Pogwizd; Robert P Robichaux; Shannon Stephens; Ronald E Stickney; Paul B Tabereaux; Derek J Dosdall; Jeffrey D Kerby; Raymond E Ideker
Effect of chest compressions on ventricular activation.

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2012: Jonathan L Respress; Natale Rolim; Darlene G Skapura; Kristine Skårdal; Ralph J van Oort; Niels Voigt; Xun Ai; Angela deAlmeida; Sayali S Dixit; Dobromir Dobrev; William S Lawrence; Na Li; Steven M Pogwizd; Thomas Wieland; Ulrik Wisløff; Xander H T Wehrens
Role of RyR2 phosphorylation at S2814 during heart failure progression.
Circulation research 2012;110(11):1474-83.
2012: Carolyn M Johnson; Steven M Pogwizd
Focal initiation of sustained and nonsustained ventricular tachycardia in a canine model of ischemic cardiomyopathy.
Journal of cardiovascular electrophysiology 2012;23(5):543-52.
2012: Jose Osorio; Steven M Pogwizd; Robert P Robichaux; Shannon Stephens; Ronald E Stickney; Paul B Tabereaux; Derek J Dosdall; Jeffrey D Kerby; Raymond E Ideker
Effect of chest compressions on ventricular activation.
The American journal of cardiology 2012;109(5):670-4.
2011: Xun Ai; Aiyang Jiang; Yunbo Ke; R John Solaro; Steven M Pogwizd
Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43.
Cardiovascular research 2011;92(1):106-14.
2011: Chengzong Han; Cheryl R Killingsworth; Steven M Pogwizd; Bin He
Noninvasive imaging of three-dimensional cardiac activation sequence during pacing and ventricular tachycardia.
Heart rhythm : the official journal of the Heart Rhythm Society 2011;8(8):1266-72.
2011: Chengzong Han; Cheryl R Killingsworth; Steven M Pogwizd; Bin He
Noninvasive reconstruction of the three-dimensional ventricular activation sequence during pacing and ventricular tachycardia in the rabbit heart.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2011;2011():1684-7.
2010: Jerry Curran; Kathy Hayes Brown; Demetrio J Santiago; Steven M Pogwizd; Donald M Bers; Thomas R Shannon
Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II.
Journal of molecular and cellular cardiology 2010;49(1):25-32.
2010: Li Li; Qi Jin; Derek J Dosdall; Jian Huang; Steven M Pogwizd; Raymond E Ideker
Activation becomes highly organized during long-duration ventricular fibrillation in canine hearts.
American journal of physiology. Heart and circulatory physiology 2010;298(6):H2046-53.
2010: Andreas Rinne; Nidhi Kapur; Jeffery D Molkentin; Steven M Pogwizd; Donald M Bers; Kathrin Banach; Lothar A Blatter
Isoform- and tissue-specific regulation of the Ca(2+)-sensitive transcription factor NFAT in cardiac myocytes and heart failure.
American journal of physiology. Heart and circulatory physiology 2010;298(6):H2001-9.
2010: Xun Ai; Weiwei Zhao; Steven M Pogwizd
Connexin43 knockdown or overexpression modulates cell coupling in control and failing rabbit left ventricular myocytes.
Cardiovascular research 2010;85(4):751-62.
2009: Raymond E Ideker; Jack M Rogers; Vladimir G Fast; Li Li; G Neal Kay; Steven M Pogwizd
Can mapping differentiate microreentry from a focus in the ventricle?
Heart rhythm : the official journal of the Heart Rhythm Society 2009;6(11):1666-9.
2008: Chengzong Han; Zhongming Liu; Xin Zhang; Steven M Pogwizd; Bin He
Noninvasive three-dimensional cardiac activation imaging from body surface potential maps: a computational and experimental study on a rabbit model.
IEEE transactions on medical imaging 2008;27(11):1622-30.
2008: Jaime Desantiago; Xun Ai; Mohammed Islam; Georgia Acuna; Mark T Ziolo; Donald M Bers; Steven M Pogwizd
Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load.
Circulation research 2008;102(11):1389-97.
2008: Mina Attin; Raymond E Ideker; Steven M Pogwizd
Mechanistic insights into ventricular arrhythmias from mapping studies in humans.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(6 Suppl):S53-8.
2008: Julie Bossuyt; Kathryn Helmstadter; Xu Wu; Hugh Clements-Jewery; Robert S Haworth; Metin Avkiran; Jody L Martin; Steven M Pogwizd; Donald M Bers
Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure.
Circulation research 2008;102(6):695-702.
2007: Tao Guo; Xun Ai; Thomas R Shannon; Steven M Pogwizd; Donald M Bers
Intra-sarcoplasmic reticulum free [Ca2+] and buffering in arrhythmogenic failing rabbit heart.
Circulation research 2007;101(8):802-10.
2007: Traian M Anghel; Steven M Pogwizd
Creating a cardiac pacemaker by gene therapy.
Medical & biological engineering & computing 2007;45(2):145-55.
2006: Chenguang Liu; Xin Zhang; Zhongming Liu; Steven M Pogwizd; Bin He
Three-dimensional myocardial activation imaging in a rabbit model.
IEEE transactions on bio-medical engineering 2006;53(9):1813-20.
2006: Peter J Lee; Steven M Pogwizd
Micropatterns of propagation.
Advances in cardiology 2006;42():86-106.
2005: Xun Ai; Jerry W Curran; Thomas R Shannon; Donald M Bers; Steven M Pogwizd
Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure.
Circulation research 2005;97(12):1314-22.
2005: Xin Zhang; Indiresha Ramachandra; Zhongming Liu; Basharat Muneer; Steven M Pogwizd; Bin He
Noninvasive three-dimensional electrocardiographic imaging of ventricular activation sequence.
American journal of physiology. Heart and circulatory physiology 2005;289(6):H2724-32.
2005: Julie Bossuyt; Xun Ai; J Randall Moorman; Steven M Pogwizd; Donald M Bers
Expression and phosphorylation of the na-pump regulatory subunit phospholemman in heart failure.
Circulation research 2005;97(6):558-65.
2005: Mark T Ziolo; Jody L Martin; Julie Bossuyt; Donald M Bers; Steven M Pogwizd
Adenoviral gene transfer of mutant phospholamban rescues contractile dysfunction in failing rabbit myocytes with relatively preserved SERCA function.
Circulation research 2005;96(8):815-7.
2005: Xun Ai; Steven M Pogwizd
Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A.
Circulation research 2005;96(1):54-63.
2004: Steven M Pogwizd; Donald M Bers
Cellular basis of triggered arrhythmias in heart failure.
Trends in cardiovascular medicine 2004;14(2):61-6.
2003: Christopher M Glenn; Steven M Pogwizd
Gene therapy to develop a genetically engineered cardiac pacemaker.
The Journal of cardiovascular nursing 2003;18(5):330-6.
2003: Thomas R Shannon; Steven M Pogwizd; Donald M Bers
Elevated sarcoplasmic reticulum Ca2+ leak in intact ventricular myocytes from rabbits in heart failure.
Circulation research 2003;93(7):592-4.
2003: Steven M Pogwizd
Prevention of ischemia-induced reentrant ventricular arrhythmias by a peptide that enhances gap junctional conductance.
Journal of cardiovascular electrophysiology 2003;14(5):521-3.
2003: Steven M Pogwizd; Karin R Sipido; Fons Verdonck; Donald M Bers
Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis.
Cardiovascular research 2003;57(4):887-96.
2003: Steven M Pogwizd
Clinical potential of sodium-calcium exchanger inhibitors as antiarrhythmic agents.
Drugs 2003;63(5):439-52.
2002: Steven M Pogwizd; Donald M Bers
Na/Ca exchange in heart failure: contractile dysfunction and arrhythmogenesis.
Annals of the New York Academy of Sciences 2002;976():454-65.
2002: Sanda Despa; Mohammed A Islam; Christopher R Weber; Steven M Pogwizd; Donald M Bers
Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged.
Circulation 2002;105(21):2543-8.
2002: Francesca J Davis; Madhu Gupta; Steven M Pogwizd; Emile A Bacha; Valluvan Jeevanandam; Mahesh P Gupta
Increased expression of alternatively spliced dominant-negative isoform of SRF in human failing hearts.
American journal of physiology. Heart and circulatory physiology 2002;282(4):H1521-33.
2002: Sanda Despa; Mohammed A Islam; Steven M Pogwizd; Donald M Bers
Intracellular [Na+] and Na+ pump rate in rat and rabbit ventricular myocytes.
The Journal of physiology 2002;539(Pt 1):133-43.
2002: Donald M Bers; Steven M Pogwizd; Klaus Schlotthauer
Upregulated Na/Ca exchange is involved in both contractile dysfunction and arrhythmogenesis in heart failure.
Basic research in cardiology 2002;97 Suppl 1():I36-42.
2002: Steven M Pogwizd; Donald M Bers
Calcium cycling in heart failure: the arrhythmia connection.
Journal of cardiovascular electrophysiology 2002;13(1):88-91.
2001: Steven M Pogwizd; Klaus Schlotthauer; L Li; W Yuan; Donald M Bers
Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness.
Circulation research 2001;88(11):1159-67.
1999: Steven M Pogwizd; M Qi; W Yuan; Allen M Samarel; Donald M Bers
Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure.
Circulation research 1999;85(11):1009-19.