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Guy Poirier

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Chemicals & Drugs

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Jana Krietsch; Marie-Christine Caron; Chantal Ethier; Jean-Philippe Gagné; Michael Hendzel; Guy G Poirier; Michèle Rouleau; Julien Vignard; Michel Vincent; Jean-Yves Masson
PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks.
Maxim Isabelle; Jean-Philippe Gagné; Imed-Eddine Gallouzi; Guy G Poirier
Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly(ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation.
Jean-Philippe Gagné; Maxim Isabelle; Isabelle Kelly; Jana Krietsch; Kyung-Mee Moon; Eric Paquet; Emilie Pic; Michel Boutin; Chantal Ethier; Leonard J Foster; Guy G Poirier
Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress.

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All Publications

2012: Jana Krietsch; Marie-Christine Caron; Chantal Ethier; Jean-Philippe Gagné; Michael Hendzel; Guy G Poirier; Michèle Rouleau; Julien Vignard; Michel Vincent; Jean-Yves Masson
PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks.
Nucleic acids research 2012;40(20):10287-301.
2012: Maxim Isabelle; Jean-Philippe Gagné; Imed-Eddine Gallouzi; Guy G Poirier
Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly(ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation.
Journal of cell science 2012;125(Pt 19):4555-66.
2012: Jean-Philippe Gagné; Maxim Isabelle; Isabelle Kelly; Jana Krietsch; Kyung-Mee Moon; Eric Paquet; Emilie Pic; Michel Boutin; Chantal Ethier; Leonard J Foster; Guy G Poirier
Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress.
Nucleic acids research 2012;40(16):7788-805.
2012: Maxim Isabelle; Imed-Eddine Gallouzi; Guy G Poirier
PARP1 parylation promotes silent locus transmission in the nucleolus: the suspicion confirmed.
Molecular cell 2012;45(6):706-7.
2012: Anand G Patel; Guy G Poirier; Silvana B De Lorenzo; Karen Flatten; Scott H Kaufmann
Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitro.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(6):1655-62.
2011: Ho Chul Kang; Han Seok Ko; Byoung Dae Lee; Yunjong Lee; Yun-Il Lee; Guy G Poirier; Joo-Ho Shin; Shaida A Andrabi; Zhikai Chi; Valina Dawson; Jean-Philippe Gagné; Ted M Dawson
Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(34):14103-8.
2011: Shaida A Andrabi; Zhikai Chi; Ted M Dawson; Jean-François Haince; Ho Chul Kang; Raymond C Koehler; Yun-Il Lee; Guy G Poirier; Andrew B West; Jian-Min Zhang; Valina Dawson
Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death.
Nature medicine 2011;17(6):692-9.
2011: Jean-Philippe Gagné; Jean-François Haince; Emilie Pic; Guy G Poirier
Affinity-based assays for the identification and quantitative evaluation of noncovalent poly(ADP-ribose)-binding proteins.
Methods in molecular biology (Clifton, N.J.) 2011;780():93-115.
2011: Yingfei Wang; No Soo Kim; Jean-Francois Haince; Ho Chul Kang; Karen K David; Shaida A Andrabi; Guy G Poirier; Valina Dawson; Ted M Dawson
Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos).
Science signaling 2011;4(167):ra20.
2010: Maxim Isabelle; Xavier Moreel; Jean-Philippe Gagné; Michèle Rouleau; Chantal Ethier; Pierre Gagné; Michael J Hendzel; Guy G Poirier
Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry.
Proteome science 2010;8():22.
2009: Nicolas Parent; Eric Winstall; Myriam Beauchemin; Claudie Paquet; Guy G Poirier; Richard Bertrand
Proteomic analysis of enriched lysosomes at early phase of camptothecin-induced apoptosis in human U-937 cells.
Journal of proteomics 2009;72(6):960-73.
2009: Jean-Philippe Gagné; Xavier Moreel; Pierre Gagné; Yves Labelle; Arnaud Droit; Mélissa Chevalier-Paré; Sylvie Bourassa; Darin McDonald; Michael Hendzel; claude prigent; Guy G Poirier
Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase.
Journal of proteome research 2009;8(2):1014-29.
2009: Jiarui Ding; Jinhong Shi; Guy G Poirier; Fang-Xiang Wu
A novel approach to denoising ion trap tandem mass spectra.
Proteome science 2009;7():9.
2009: An-Min Zou; Fang-Xiang Wu; Jia-Rui Ding; Guy G Poirier
Quality assessment of tandem mass spectra using support vector machine (SVM).
BMC bioinformatics 2009;10 Suppl 1():S49.
2008: Annie Lauzier; Anne-Marie Simao-Beaunoir; Sylvie Bourassa; Guy G Poirier; Brian Talbot; Carole Beaulieu
Effect of potato suberin on Streptomyces scabies proteome.
Molecular plant pathology 2008;9(6):753-62.
2008: Danielle Caron; Eric Winstall; Yutaka Inaguma; Sébastien Michaud; Francine Lettre; Sylvie Bourassa; Isabelle Kelly; Guy G Poirier; Robert L Faure; Robert M Tanguay
Proteomic characterization of mouse cytosolic and membrane prostate fractions: high levels of free SUMO peptides are androgen-regulated.
Journal of proteome research 2008;7(10):4492-9.
2008: Alexandra Côté-Martin; Cary A. Moody; Amélie Fradet-Turcotte; Claudia M D'Abramo; Michael Lehoux; Simon Joubert; Guy G Poirier; Benoit Coulombe; Laimonis A Laimins; Jacques Archambault
Human papillomavirus E1 helicase interacts with the WD repeat protein p80 to promote maintenance of the viral genome in keratinocytes.
Journal of virology 2008;82(3):1271-83.
2008: Jean-François Haince; Darin McDonald; Amélie Rodrigue; Ugo Déry; Jean-Yves Masson; Michael Hendzel; Guy G Poirier
PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites.
The Journal of biological chemistry 2008;283(2):1197-208.
2008: Fang-Xiang Wu; Pierre Gagné; Arnaud Droit; Guy G Poirier
Quality assessment of peptide tandem mass spectra.
BMC bioinformatics 2008;9 Suppl 6():S13.
2008: Marilena Cojocaru; Célia Jeronimo; Diane Forget; Annie Bouchard; Dominique Bergeron; Pierre Côte; Guy G Poirier; Jack Greenblatt; Benoit Coulombe
Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription.
The Biochemical journal 2008;409(1):139-47.
2007: Jolyne Drummelsmith; Eric Winstall; Michel G Bergeron; Guy G Poirier; Marc Ouellette
Comparative proteomics analyses reveal a potential biomarker for the detection of vancomycin-intermediate Staphylococcus aureus strains.
Journal of proteome research 2007;6(12):4690-702.
2007: Chantal Ethier; Yves Labelle; Guy G Poirier
PARP-1-induced cell death through inhibition of the MEK/ERK pathway in MNNG-treated HeLa cells.
Apoptosis : an international journal on programmed cell death 2007;12(11):2037-49.
2007: Marc F Poitras; David W Koh; Seong-Woon Yu; Shaida A Andrabi; Allen S Mandir; Guy G Poirier; Valina Dawson; Ted M Dawson
Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain.
Neuroscience 2007;148(1):198-211.
2007: Célia Jeronimo; Diane Forget; Annie Bouchard; Qintong Li; Gordon Chua; Christian Poitras; Cynthia Thérien; Dominique Bergeron; Sylvie Bourassa; Jack Greenblatt; Benoit Chabot; Guy G Poirier; Timothy R Hughes; Mathieu Blanchette; David H Price; Benoit Coulombe
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
Molecular cell 2007;27(2):262-74.
2007: Jean-François Haince; Sergei Kozlov; Valina Dawson; Ted M Dawson; Michael Hendzel; Martin F Lavin; Guy G Poirier
Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents.
The Journal of biological chemistry 2007;282(22):16441-53.
2007: Nuri Gueven; Olivier J Becherel; Orla Howe; Philip Chen; Jean-François Haince; Marie-Eve Ouellet; Guy G Poirier; N Waterhouse; M Fusser; Bernd Epe; Josiane Ménissier de Murcia; Gilbert de Murcia; C H McGowan; Robert Parton; Carmel Mothersill; Padraic Grattan-Smith; Martin F Lavin
A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance.
Cell death and differentiation 2007;14(6):1149-61.
2007: Hélène Sénéchal; Guy G Poirier; Benoit Coulombe; Laimonis A Laimins; Jacques Archambault
Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4.
Virology 2007;358(1):10-7.
2007: Michèle Rouleau; D McDonald; Pierre Gagné; Marie-Eve Ouellet; Arnaud Droit; Joanna M Hunter; Stephanie Dutertre; claude prigent; Michael Hendzel; Guy G Poirier
PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery.
Journal of cellular biochemistry 2007;100(2):385-401.
2007: Xiaoling Li; Masaaki Nemoto; Z Xu; Seong-Woon Yu; Mika Shimoji; Shaida A Andrabi; Jean-François Haince; Guy G Poirier; Ted M Dawson; Valina Dawson; Raymond C Koehler
Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus.
Neuroscience 2007;144(1):56-65.
2007: Arnaud Droit; Joanna M Hunter; Michèle Rouleau; Chantal Ethier; Aude Picard-Cloutier; David Bourgais; Guy G Poirier
PARPs database: a LIMS systems for protein-protein interaction data mining or laboratory information management system.
BMC bioinformatics 2007;8():483.
2007: Jean-Philippe Gagné; Chantal Ethier; Pierre Gagné; Geneviève Mercier; Marie-Eve Bonicalzi; Anne-Marie Mes-Masson; Arnaud Droit; Eric Winstall; Maxim Isabelle; Guy G Poirier
Comparative proteome analysis of human epithelial ovarian cancer.
Proteome science 2007;5():16.
2006: Shaida A Andrabi; No Soo Kim; Seong-Woon Yu; Hongmin Wang; David W Koh; Masayuki Sasaki; Judith A Klaus; Takashi Otsuka; Zhizheng Zhang; Raymond C Koehler; Patricia D Hurn; Guy G Poirier; Valina Dawson; Ted M Dawson
Poly(ADP-ribose) (PAR) polymer is a death signal.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18308-13.
2006: Seong-Woon Yu; Shaida A Andrabi; Hongmin Wang; No Soo Kim; Guy G Poirier; Ted M Dawson; Valina Dawson
Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18314-9.
2006: Jean-François Haince; Michèle Rouleau; Guy G Poirier
Transcription. Gene expression needs a break to unwind before carrying on.
Science (New York, N.Y.) 2006;312(5781):1752-3.
2006: Jean-Philippe Gagné; Michael Hendzel; Arnaud Droit; Guy G Poirier
The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives.
Current opinion in cell biology 2006;18(2):145-51.
2006: Jean-François Haince; Marie-Eve Ouellet; Darin McDonald; Michael Hendzel; Guy G Poirier
Dynamic relocation of poly(ADP-ribose) glycohydrolase isoforms during radiation-induced DNA damage.
Biochimica et biophysica acta 2006;1763(2):226-37.
2006: Fang-Xiang Wu; Pierre Gagné; Arnaud Droit; Guy G Poirier
RT-PSM, a real-time program for peptide-spectrum matching with statistical significance.
Rapid communications in mass spectrometry : RCM 2006;20(8):1199-208.
2005: Jean-Philippe Gagné; Marie-Eve Bonicalzi; Pierre Gagné; Marie-Eve Ouellet; Michael Hendzel; Guy G Poirier
Poly(ADP-ribose) glycohydrolase is a component of the FMRP-associated messenger ribonucleoparticles.
The Biochemical journal 2005;392(Pt 3):499-509.
2005: Jean-François Haince; Michèle Rouleau; Michael Hendzel; Jean-Yves Masson; Guy G Poirier
Targeting poly(ADP-ribosyl)ation: a promising approach in cancer therapy.
Trends in molecular medicine 2005;11(10):456-63.
2005: Jean-Philippe Gagné; Pierre Gagné; Joanna M Hunter; Marie-Eve Bonicalzi; Jean-François Lemay; Isabelle Kelly; Cecile Le Page; Diane Provencher; Anne-Marie Mes-Masson; Arnaud Droit; David Bourgais; Guy G Poirier
Proteome profiling of human epithelial ovarian cancer cell line TOV-112D.
Molecular and cellular biochemistry 2005;275(1-2):25-55.
2005: Fang-Xiang Wu; Guy G Poirier; W J Zhang
Inferring gene regulatory networks with time delays using a genetic algorithm.
Systems biology 2005;152(2):67-74.
2005: Marie-Eve Bonicalzi; Jean-François Haince; Arnaud Droit; Guy G Poirier
Regulation of poly(ADP-ribose) metabolism by poly(ADP-ribose) glycohydrolase: where and when?
Cellular and molecular life sciences : CMLS 2005;62(7-8):739-50.
2005: Arnaud Droit; Guy G Poirier; Joanna M Hunter
Experimental and bioinformatic approaches for interrogating protein-protein interactions to determine protein function.
Journal of molecular endocrinology 2005;34(2):263-80.
2004: David W Koh; Ann M Lawler; Marc F Poitras; Masayuki Sasaki; Sigrid Wattler; Michael Nehls; Tobias Stoeger; Guy G Poirier; Valina Dawson; Ted M Dawson
Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(51):17699-704.
2004: Hongmin Wang; Seong-Woon Yu; David W Koh; Jasmine Lew; Carmen Coombs; William J Bowers; Howard Federoff; Guy G Poirier; Ted M Dawson; Valina Dawson
Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(48):10963-73.
2004: Michèle Rouleau; Rémy A Aubin; Guy G Poirier
Poly(ADP-ribosyl)ated chromatin domains: access granted.
Journal of cell science 2004;117(Pt 6):815-25.
2004: Jean-François Haince; Guy G Poirier; James B Kirkland
Nonisotopic methods for determination of poly(ADP-ribose) levels and detection of poly(ADP-ribose) polymerase.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2004;Chapter 18():Unit18.7.
2003: Marie-Eve Bonicalzi; Momchil D Vodenicharov; Miryan Coulombe; Jean-Philippe Gagné; Guy G Poirier
Alteration of poly(ADP-ribose) glycohydrolase nucleocytoplasmic shuttling characteristics upon cleavage by apoptotic proteases.
Biology of the cell / under the auspices of the European Cell Biology Organization 2003;95(9):635-44.
2003: Véronique J Bouchard; Michèle Rouleau; Guy G Poirier
PARP-1, a determinant of cell survival in response to DNA damage.
Experimental hematology 2003;31(6):446-54.
2003: Sonya Wieler; Jean-Philippe Gagné; Homayoun Vaziri; Guy G Poirier; Samuel Benchimol
Poly(ADP-ribose) polymerase-1 is a positive regulator of the p53-mediated G1 arrest response following ionizing radiation.
The Journal of biological chemistry 2003;278(21):18914-21.
2003: Jean-Philippe Gagné; Joanna M Hunter; Benoît Labrecque; Benoit Chabot; Guy G Poirier
A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins.
The Biochemical journal 2003;371(Pt 2):331-40.
2002: Nicolas Lacoste; Rhea T Utley; Joanna M Hunter; Guy G Poirier; Jacques Côte
Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.
The Journal of biological chemistry 2002;277(34):30421-4.
2002: Seong-Woon Yu; Hongmin Wang; Marc F Poitras; Carmen Coombs; William J Bowers; Howard Federoff; Guy G Poirier; Ted M Dawson; Valina Dawson
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor.
Science (New York, N.Y.) 2002;297(5579):259-63.
2002: Daria Pereg; Eric Dewailly; Guy G Poirier; Pierre Ayotte
Environmental exposure to polychlorinated biphenyls and placental CYP1A1 activity in Inuit women from northern Québec.
Environmental health perspectives 2002;110(6):607-12.
2002: Ann C Boyonoski; Jennifer C Spronck; Robert M Jacobs; Girish M Shah; Guy G Poirier; James B Kirkland
Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats.
The Journal of nutrition 2002;132(1):115-20.
2002: Ann C Boyonoski; Jennifer C Spronck; Lisa M Gallacher; Robert M Jacobs; Girish M Shah; Guy G Poirier; James B Kirkland
Niacin deficiency decreases bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats.
The Journal of nutrition 2002;132(1):108-14.
2001: D D'Amours; Frederic Sallmann; V M Dixit; Guy G Poirier
Gain-of-function of poly(ADP-ribose) polymerase-1 upon cleavage by apoptotic proteases: implications for apoptosis.
Journal of cell science 2001;114(Pt 20):3771-8.
2001: Jean-Philippe Gagné; Rashmi G Shah; Guy G Poirier
Analysis of ADP-ribose polymer sizes in intact cells.
Molecular and cellular biochemistry 2001;224(1-2):183-5.
2001: L Davidovic; Momchil D Vodenicharov; EB Affar; Guy G Poirier
Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism.
Experimental cell research 2001;268(1):7-13.
2001: S Gobeil; C C Boucher; D Nadeau; Guy G Poirier
Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases.
Cell death and differentiation 2001;8(6):588-94.
2001: EB Affar; M Germain; Eric Winstall; Momchil D Vodenicharov; Rashmi G Shah; G S Salvesen; Guy G Poirier
Caspase-3-mediated processing of poly(ADP-ribose) glycohydrolase during apoptosis.
The Journal of biological chemistry 2001;276(4):2935-42.
2000: Allen S Mandir; Marc F Poitras; A R Berliner; William Joseph Herring; DB Guastella; A Feldman; Guy G Poirier; ZQ Wang; Ted M Dawson; Valina Dawson
NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(21):8005-11.
2000: Momchil D Vodenicharov; Frederic Sallmann; Masahiko S Satoh; Guy G Poirier
Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1.
Nucleic acids research 2000;28(20):3887-96.
2000: Frederic Sallmann; Momchil D Vodenicharov; Z Q Wang; Guy G Poirier
Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks.
The Journal of biological chemistry 2000;275(20):15504-11.
2000: Ann C Boyonoski; Lisa M Gallacher; M M ApSimon; Robert M Jacobs; Girish M Shah; Guy G Poirier; James B Kirkland
Niacin deficiency in rats increases the severity of ethylnitrosourea-induced anemia and leukopenia.
The Journal of nutrition 2000;130(5):1102-7.
2000: Patrick Levallois; Pierre Ayotte; R Louchini; Thérèse Desrosiers; H Baribeau; D Phaneuf; Suzanne Gingras; P Dumas; John Zee; Guy G Poirier
Sources of nitrate exposure in residents of rural areas in Quebec, Canada.
Journal of exposure analysis and environmental epidemiology 2000;10(2):188-95.
1999: M Germain; EB Affar; D D'Amours; V M Dixit; G S Salvesen; Guy G Poirier
Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7.
The Journal of biological chemistry 1999;274(40):28379-84.
1999: Eric Winstall; EB Affar; R Shah; Sylvie Bourassa; Anna Scovassi; Guy G Poirier
Preferential perinuclear localization of poly(ADP-ribose) glycohydrolase.
Experimental cell research 1999;251(2):372-8.
1999: D D'Amours; S Desnoyers; I D'Silva; Guy G Poirier
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions.
The Biochemical journal 1999;342 ( Pt 2)():249-68.
1999: EB Affar; PJ Duriez; Rashmi G Shah; Eric Winstall; M Germain; C Boucher; Sylvie Bourassa; James B Kirkland; Guy G Poirier
Immunological determination and size characterization of poly(ADP-ribose) synthesized in vitro and in vivo.
Biochimica et biophysica acta 1999;1428(2-3):137-46.
1999: J Lagueux; Daria Pereg; Pierre Ayotte; Eric Dewailly; Guy G Poirier
Cytochrome P450 CYP1A1 enzyme activity and DNA adducts in placenta of women environmentally exposed to organochlorines.
Environmental research 1999;80(4):369-82.
1999: EB Affar; Rashmi G Shah; Guy G Poirier
Poly(ADP-ribose) turnover in quail myoblast cells: relation between the polymer level and its catabolism by glycohydrolase.
Molecular and cellular biochemistry 1999;193(1-2):127-35.
1999: Ann C Boyonoski; Lisa M Gallacher; M M ApSimon; Robert M Jacobs; Girish M Shah; Guy G Poirier; James B Kirkland
Niacin deficiency increases the sensitivity of rats to the short and long term effects of ethylnitrosourea treatment.
Molecular and cellular biochemistry 1999;193(1-2):83-7.
1999: Kumiko Samejima; Phyllis A Svingen; Guriqbal S Basi; T Kottke; Peter W Mesner; L Stewart; F Durrieu; Guy G Poirier; E S Alnemri; J J Champoux; Scott H Kaufmann; William C Earnshaw
Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis.
The Journal of biological chemistry 1999;274(7):4335-40.
1999: I D'Silva; J D Pelletier; J Lagueux; D D'Amours; M A Chaudhry; Michael Weinfeld; Susan Lees-Miller; Guy G Poirier
Relative affinities of poly(ADP-ribose) polymerase and DNA-dependent protein kinase for DNA strand interruptions.
Biochimica et biophysica acta 1999;1430(1):119-26.
1999: Eric Winstall; EB Affar; R Shah; Sylvie Bourassa; Anna Scovassi; Guy G Poirier
Poly(ADP-ribose) glycohydrolase is present and active in mammalian cells as a 110-kDa protein.
Experimental cell research 1999;246(2):395-8.
1998: I D'Silva; Guy G Poirier; Michèle C Heath
Activation of cysteine proteases in cowpea plants during the hypersensitive response--a form of programmed cell death.
Experimental cell research 1998;245(2):389-99.
1998: Frederic Sallmann; Y D Plancke; Guy G Poirier
Rapid detection of poly(ADP-ribose) polymerase by enzyme-linked immunosorbent assay during its purification and improvement of its purification.
Molecular and cellular biochemistry 1998;185(1-2):199-203.
1998: EB Affar; M Dufour; Guy G Poirier; D Nadeau
Isolation, purification and partial characterization of chloragocytes from the earthworm species Lumbricus terrestris.
Molecular and cellular biochemistry 1998;185(1-2):123-33.
1998: D D'Amours; M Germain; K Orth; V M Dixit; Guy G Poirier
Proteolysis of poly(ADP-ribose) polymerase by caspase 3: kinetics of cleavage of mono(ADP-ribosyl)ated and DNA-bound substrates.
Radiation research 1998;150(1):3-10.
1998: EB Affar; PJ Duriez; Rashmi G Shah; Frederic Sallmann; Sylvie Bourassa; JH Küpper; Alexander Bürkle; Guy G Poirier
Immunodot blot method for the detection of poly(ADP-ribose) synthesized in vitro and in vivo.
Analytical biochemistry 1998;259(2):280-3.
1997: JC Hoflack; M J Durand; Guy G Poirier; A Maul; Paule Vasseur
Alteration in methyl-methanesulfonate-induced poly(ADP-ribosyl)ation by 2-butoxyethanol in Syrian hamster embryo cells.
Carcinogenesis 1997;18(12):2333-8.
1997: PE Warburton; CA Cooke; Sylvie Bourassa; O Vafa; B A Sullivan; Gail Stetten; Giorgio Gimelli; D Warburton; Chris Tyler-Smith; Kevin Sullivan; Guy G Poirier; William C Earnshaw
Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres.
Current biology : CB 1997;7(11):901-4.
1997: J Diogène; M Dufour; Guy G Poirier; D Nadeau
Extrusion of earthworm coelomocytes: comparison of the cell populations recovered from the species Lumbricus terrestris, Eisenia fetida and Octolasion tyrtaeum.
Laboratory animals 1997;31(4):326-36.
1997: J Lagueux; EB Affar; D Nadeau; Pierre Ayotte; Eric Dewailly; Guy G Poirier
A microassay for the detection of low levels of cytochrome P450 O-deethylation activities with alkoxyresorufin substrates.
Molecular and cellular biochemistry 1997;175(1-2):125-9.
1997: Homayoun Vaziri; M D West; Rich Allsopp; TS Davison; Y S Wu; Cheryl H Arrowsmith; Guy G Poirier; Samuel Benchimol
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.
The EMBO journal 1997;16(19):6018-33.
1997: Michael Weinfeld; M A Chaudhry; D D'Amours; J D Pelletier; Guy G Poirier; Lawrence F Povirk; Susan Lees-Miller
Interaction of DNA-dependent protein kinase and poly(ADP-ribose) polymerase with radiation-induced DNA strand breaks.
Radiation research 1997;148(1):22-8.
1997: D D'Amours; PJ Duriez; K Orth; Rashmi G Shah; V M Dixit; W C Earnshaw; E S Alnemri; Guy G Poirier
Purification of the death substrate poly(ADP-ribose) polymerase.
Analytical biochemistry 1997;249(1):106-8.
1997: Rashmi G Shah; J Lagueux; S Kapur; Patrick Levallois; Pierre Ayotte; M Tremblay; John Zee; Guy G Poirier
Determination of genotoxicity of the metabolites of the pesticides Guthion, Sencor, Lorox, Reglone, Daconil and Admire by 32P-postlabeling.
Molecular and cellular biochemistry 1997;169(1-2):177-84.
1997: A Takahashi; Pascal J Goldschmidt-Clermont; E S Alnemri; T Fernandes-Alnemri; K Yoshizawa-Kumagaya; K Nakajima; M Sasada; Guy G Poirier; William C Earnshaw
Inhibition of ICE-related proteases (caspases) and nuclear apoptosis by phenylarsine oxide.
Experimental cell research 1997;231(1):123-31.
1997: L Van Gool; Ralph Meyer; E Tobiasch; Celina Cziepluch; Jean-Claude Jauniaux; Antoaneta Mincheva; Peter Lichter; Guy G Poirier; Alexander Bürkle; JH Küpper
Overexpression of human poly(ADP-ribose) polymerase in transfected hamster cells leads to increased poly(ADP-ribosyl)ation and cellular sensitization to gamma irradiation.
European journal of biochemistry / FEBS 1997;244(1):15-20.
1997: PJ Duriez; S Desnoyers; JC Hoflack; Girish M Shah; B Morelle; Sylvie Bourassa; Guy G Poirier; B Talbot
Characterization of anti-peptide antibodies directed towards the automodification domain and apoptotic fragment of poly (ADP-ribose) polymerase.
Biochimica et biophysica acta 1997;1334(1):65-72.
1997: Frederic Sallmann; Sylvie Bourassa; J Saint-Cyr; Guy G Poirier
Characterization of antibodies specific for the caspase cleavage site on poly(ADP-ribose) polymerase: specific detection of apoptotic fragments and mapping of the necrotic fragments of poly(ADP-ribose) polymerase.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1997;75(4):451-6.
1997: JC Hoflack; Paule Vasseur; Guy G Poirier
Glycol ethers induce death and necrosis in human leukemia cells.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1997;75(4):415-25.