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Miriam Poirier

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Chemicals & Drugs

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Kaarthik John; Gail McMullen; Ofelia A Olivero; Igor P Pogribny; Frederick A Beland; Mona I Churchwell; M Margaret Pratt; Miriam C Poirier
Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days.
Miriam C Poirier
Chemical-induced DNA damage and human cancer risk.
Yongmin Liu; Phuonggiang Nguyen; Tara Z Baris; Miriam C Poirier
Molecular analysis of mitochondrial compromise in rodent cardiomyocytes exposed long term to nucleoside reverse transcriptase inhibitors (NRTIs).

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2012: Kaarthik John; Gail McMullen; Ofelia A Olivero; Igor P Pogribny; Frederick A Beland; Mona I Churchwell; M Margaret Pratt; Miriam C Poirier
Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days.
Carcinogenesis 2012;33(11):2236-41.
2012: Miriam C Poirier
Chemical-induced DNA damage and human cancer risk.
Discovery medicine 2012;14(77):283-8.
2012: Yongmin Liu; Phuonggiang Nguyen; Tara Z Baris; Miriam C Poirier
Molecular analysis of mitochondrial compromise in rodent cardiomyocytes exposed long term to nucleoside reverse transcriptase inhibitors (NRTIs).
Cardiovascular toxicology 2012;12(2):123-34.
2011: Tracey Einem Lindeman; Miriam C Poirier; Rao L Divi
The resveratrol analogue, 2,3',4,5'-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzo[a]pyrene-DNA adduct formation in MCF-7 cells exposed to benzo[a]pyrene.
Mutagenesis 2011;26(5):629-35.
2011: M Margaret Pratt; Senait Afework; Kaarthik John; Allan B MacLean; David H Phillips; Miriam C Poirier
Polycyclic aromatic hydrocarbon (PAH) exposure and DNA adduct semi-quantitation in archived human tissues.
International journal of environmental research and public health 2011;8(7):2675-91.
2011: M Margaret Pratt; Leon C King; Linda D Adams; Kaarthik John; Paul Sirajuddin; Ofelia A Olivero; David K Manchester; Radim J Sram; David M DeMarini; Miriam C Poirier
Assessment of multiple types of DNA damage in human placentas from smoking and nonsmoking women in the Czech Republic.
Environmental and molecular mutagenesis 2011;52(1):58-68.
2010: Rao L Divi; Tracey L Einem; Sarah L Leonard Fletcher; Marie E Shockley; Maryanne M Kuo; Marisa C St Claire; Anthony Cook; Kunio Nagashima; Steven W Harbaugh; Jeffrey W Harbaugh; Miriam C Poirier
Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs).
Toxicological sciences : an official journal of the Society of Toxicology 2010;118(1):191-201.
2010: Kaarthik John; Rao L Divi; Channa Keshava; Christine C Orozco; Marie E Schockley; Diana L Richardson; Miriam C Poirier; Joginder Nath; Ainsley Weston
CYP1A1 and CYP1B1 gene expression and DNA adduct formation in normal human mammary epithelial cells exposed to benzo[a]pyrene in the absence or presence of chlorophyllin.
Cancer letters 2010;292(2):254-60.
2010: Salina M Torres; Rao L Divi; Dale M Walker; Consuelo L McCash; Meghan M Carter; Matthew J Campen; Tracey L Einem; Yvonne Chu; Steven K Seilkop; Huining Kang; Miriam C Poirier; Vernon E Walker
In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue.
Cardiovascular toxicology 2010;10(2):87-99.
2010: Ofelia A Olivero; Irma L Vazquez; Catherine C Cooch; Jessica Ming; Emily Keller; Mia Yu; Jennifer P Borojerdi; Hannan M Braun; Edward McKee; Miriam C Poirier
Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells.
Toxicological sciences : an official journal of the Society of Toxicology 2010;115(1):109-17.
2010: Salina M Torres; Thomas H March; Meghan M Carter; Consuelo L McCash; Steven K Seilkop; Miriam C Poirier; Dale M Walker; Vernon E Walker
In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue.
Cardiovascular toxicology 2010;10(1):37-50.
2009: Mia Yu; Yvona Ward; Miriam C Poirier; Ofelia A Olivero
Centrosome amplification induced by the antiretroviral nucleoside reverse transcriptase inhibitors lamivudine, stavudine, and didanosine.
Environmental and molecular mutagenesis 2009;50(8):718-24.
2009: Dale M Walker; Adriana E Kajon; Salina M Torres; Meghan M Carter; Consuelo L McCash; James A Swenberg; Patricia B Upton; Andrew W Hardy; Ofelia A Olivero; Gene M Shearer; Miriam C Poirier; Vernon E Walker
WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication.
Environmental and molecular mutagenesis 2009;50(6):460-72.
2009: Jennifer P Borojerdi; Jessica Ming; Catherine Cooch; Yvona Ward; Cristina Semino-Mora; Mia Yu; Hannan M Braun; Barbara J Taylor; Miriam C Poirier; Ofelia A Olivero
Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells.
Mutation research 2009;665(1-2):67-74.
2009: Kaarthik John; Narasimhan Ragavan; M Margaret Pratt; Paras B Singh; Salah Al-Buheissi; Shyam S Matanhelia; David H Phillips; Miriam C Poirier; Francis L Martin
Quantification of phase I/II metabolizing enzyme gene expression and polycyclic aromatic hydrocarbon-DNA adduct levels in human prostate.
The Prostate 2009;69(5):505-19.
2009: Channa Keshava; Rao L Divi; Tracey L Einem; Diana L Richardson; Sarah L Leonard; Nagalakshmi Keshava; Miriam C Poirier; Ainsley Weston
Chlorophyllin significantly reduces benzo[a]pyrene-DNA adduct formation and alters cytochrome P450 1A1 and 1B1 expression and EROD activity in normal human mammary epithelial cells.
Environmental and molecular mutagenesis 2009;50(2):134-44.
2009: Laura J Schild-Hay; Tarek A Leil; Rao L Divi; Ofelia A Olivero; Ainsley Weston; Miriam C Poirier
Tamoxifen induces expression of immune response-related genes in cultured normal human mammary epithelial cells.
Cancer research 2009;69(3):1150-5.
2009: Miriam C Poirier; Ofelia A Olivero; Andrew W Hardy; Genoveffa Franchini; Jennifer P Borojerdi; Vernon E Walker; Dale M Walker; Gene M Shearer
Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo.
AIDS research and therapy 2009;6():24.
2008: Lauren A Courter; Andreas Luch; Tamara Musafia-Jeknic; Volker M Arlt; Kay Fischer; Robert J Bildfell; Cliff Pereira; David H Phillips; Miriam C Poirier; William M Baird
The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo.
Cancer letters 2008;265(1):135-47.
2008: Ofelia A Olivero; Jessica M Ming; Shreyasi Das; Irma L Vazquez; Diana L Richardson; Ainsley Weston; Miriam C Poirier
Human inter-individual variability in metabolism and genotoxic response to zidovudine.
Toxicology and applied pharmacology 2008;228(2):158-64.
2008: Rao L Divi; Daniel R Doerge; Nathan C Twaddle; Marie E Shockley; Marisa C St Claire; Jeffrey W Harbaugh; Steven W Harbaugh; Miriam C Poirier
Metabolism and pharmacokinetics of the combination Zidovudine plus Lamivudine in the adult Erythrocebus patas monkey determined by liquid chromatography-tandem mass spectrometric analysis.
Toxicology and applied pharmacology 2008;226(2):206-11.
2007: M Margaret Pratt; Paul Sirajuddin; Miriam C Poirier; Mark Schiffman; Andrew G. Glass; David R Scott; Brenda B Rush; Ofelia A Olivero; Philip E Castle
Polycyclic aromatic hydrocarbon-DNA adducts in cervix of women infected with carcinogenic human papillomavirus types: an immunohistochemistry study.
Mutation research 2007;624(1-2):114-23.
2007: Rao L Divi; Sarah L Leonard; Brettania L Walker; Maryanne M Kuo; Marie E Shockley; Marisa C St Claire; Kunio Nagashima; Steven W Harbaugh; Jeffrey W Harbaugh; Miriam C Poirier
Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age.
Toxicological sciences : an official journal of the Society of Toxicology 2007;99(1):203-13.
2007: Marc Gunter; Rao L Divi; Martin Kulldorff; Roel Vermeulen; Kathryn J Haverkos; Maryanne M Kuo; Paul T Strickland; Miriam C Poirier; Nathaniel Rothman; Rashmi Sinha
Leukocyte polycyclic aromatic hydrocarbon-DNA adduct formation and colorectal adenoma.
Carcinogenesis 2007;28(7):1426-9.
2007: Salina M Torres; Dale M Walker; Meghan M Carter; Dennis L Cook; Consuelo L McCash; Edmund M Cordova; Ofelia A Olivero; Miriam C Poirier; Vernon E Walker
Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations.
Environmental and molecular mutagenesis 2007;48(3-4):224-38.
2007: Patricia A Escobar; Ofelia A Olivero; Nancy A Wade; Elaine J Abrams; Carol J Nesel; Roberta B Ness; Richard D Day; Billy W Day; Quanxin Meng; J Patrick O'Neill; Dale M Walker; Miriam C Poirier; Vernon E Walker; William L Bigbee
Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.
Environmental and molecular mutagenesis 2007;48(3-4):330-43.
2007: Vernon E Walker; Miriam C Poirier
Special issue on health risks of perinatal exposure to nucleoside reverse transcriptase inhibitors.
Environmental and molecular mutagenesis 2007;48(3-4):159-65.
2007: Quanxin Meng; Ofelia A Olivero; Michael J Fasco; Ronald Bellisario; Laurence S Kaminsky; Kenneth A Pass; Nancy A Wade; Elaine J Abrams; Carol J Nesel; Roberta B Ness; William L Bigbee; J Patrick O'Neill; Dale M Walker; Miriam C Poirier; Vernon E Walker
Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs.
Environmental and molecular mutagenesis 2007;48(3-4):307-21.
2007: Rao L Divi; Kathryn J Haverkos; Juliette A Humsi; Marie E Shockley; Chandrasekhar Thamire; Kunio Nagashima; Ofelia A Olivero; Miriam C Poirier
Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to Zidovudine.
Environmental and molecular mutagenesis 2007;48(3-4):179-89.
2007: Rao L Divi; Sarah L Leonard; Maryanne M Kuo; Kunio Nagashima; Chandrasekhar Thamire; Marisa C St Claire; Nancy A Wade; Vernon E Walker; Miriam C Poirier
Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity.
Environmental and molecular mutagenesis 2007;48(3-4):201-9.
2007: Hilde E van Gijssel; Tarek A Leil; Wendy C Weinberg; Rao L Divi; Ofelia A Olivero; Miriam C Poirier
Cisplatin-DNA damage in p21WAF1/Cip1 deficient mouse keratinocytes exposed to cisplatin.
Mutagenesis 2007;22(1):49-54.
2006: Brinda Mahadevan; Vikram Arora; Laura J Schild; Channa Keshava; Melissa L Cate; Patrick L Iversen; Miriam C Poirier; Ainsley Weston; Cliff Pereira; William M Baird
Reduction in tamoxifen-induced CYP3A2 expression and DNA adducts using antisense technology.
Molecular carcinogenesis 2006;45(2):118-25.
2005: Frederick A Beland; Mona I Churchwell; Linda S Von Tungeln; Shoujun Chen; Peter P Fu; Sandra J Culp; Bernadette Schoket; Erika Gyorffy; János Minárovits; Miriam C Poirier; Elise D Bowman; Ainsley Weston; Daniel R Doerge
High-performance liquid chromatography electrospray ionization tandem mass spectrometry for the detection and quantitation of benzo[a]pyrene-DNA adducts.
Chemical research in toxicology 2005;18(8):1306-15.
2005: Channa Keshava; Rao L Divi; Diana L Whipkey; Bonnie L Frye; Erin C McCanlies; Maryanne Kuo; Miriam C Poirier; Ainsley Weston
Induction of CYP1A1 and CYP1B1 and formation of carcinogen-DNA adducts in normal human mammary epithelial cells treated with benzo[a]pyrene.
Cancer letters 2005;221(2):213-24.
2005: Ofelia A Olivero; Agueda M Tejera; Juan J Fernandez; Barbara J Taylor; Shreyasi Das; Rao L Divi; Miriam C Poirier
Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells.
Mutagenesis 2005;20(2):139-46.
2005: Laura J Schild; David H Phillips; Martin R Osborne; Alan Hewer; Frederick A Beland; Mona I Churchwell; Karen Brown; Margaret Gaskell; Elizabeth Wright; Miriam C Poirier
Hepatic DNA adduct dosimetry in rats fed tamoxifen: a comparison of methods.
Mutagenesis 2005;20(2):115-24.
2005: Maureen R Gwinn; Channa Keshava; Ofelia A Olivero; Juliette A Humsi; Miriam C Poirier; Ainsley Weston
Transcriptional signatures of normal human mammary epithelial cells in response to benzo[a]pyrene exposure: a comparison of three microarray platforms.
Omics : a journal of integrative biology 2005;9(4):334-50.
2005: Rao L Divi; Sarah L Leonard; Maryanne M Kuo; Brettania L Walker; Christine C Orozco; Marisa C St Claire; Kunio Nagashima; Steven W Harbaugh; Jeffrey W Harbaugh; Chandrasekhar Thamire; Craig A Sable; Miriam C Poirier
Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors.
Cardiovascular toxicology 2005;5(3):333-46.
2004: Miriam C Poirier; Ofelia A Olivero; Dale M Walker; Vernon E Walker
Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs.
Toxicology and applied pharmacology 2004;199(2):151-61.
2004: Miriam C Poirier
Chemical-induced DNA damage and human cancer risk.
Nature reviews. Cancer 2004;4(8):630-7.
2004: Erika Gyorffy; Lívia Anna; Zoltán Gyori; Judit Segesdi; János Minárovits; Ibolya Soltész; Szilárd Kostic; Attila Csekeo; Miriam C Poirier; Bernadette Schoket
DNA adducts in tumour, normal peripheral lung and bronchus, and peripheral blood lymphocytes from smoking and non-smoking lung cancer patients: correlations between tissues and detection by 32P-postlabelling and immunoassay.
Carcinogenesis 2004;25(7):1201-9.
2004: Rao L Divi; Vernon E Walker; Nancy A Wade; Kunio Nagashima; Steven K Seilkop; Mary Ellen Adams; Carol J Nesel; J Patrick O'Neill; Elaine J Abrams; Miriam C Poirier
Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir.
AIDS (London, England) 2004;18(7):1013-21.
2004: Hilde E van Gijssel; Laura J Schild; Danielle L Watt; Mark J Roth; Guo-Qing Wang; Sanford M Dawsey; Paul S Albert; You-Lin Qiao; Philip R Taylor; Zhi-Wei Dong; Miriam C Poirier
Polycyclic aromatic hydrocarbon-DNA adducts determined by semiquantitative immunohistochemistry in human esophageal biopsies taken in 1985.
Mutation research 2004;547(1-2):55-62.
2004: Dale M Walker; Miriam C Poirier; Matthew J Campen; Dennis L Cook; Rao L Divi; Kunio Nagashima; Amie K Lund; Patsy Y Cossey; Fletcher F Hahn; Vernon E Walker
Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.
Cardiovascular toxicology 2004;4(2):133-53.
2004: Mariana Gerschenson; Vi Nguyen; Ember L Ewings; Andrea Ceresa; Jaclyn A Shaw; Marisa C St Claire; Kunio Nagashima; Steven W Harbaugh; Jeffrey W Harbaugh; Ofelia A Olivero; Rao L Divi; Paul S Albert; Miriam C Poirier
Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine.
AIDS research and human retroviruses 2004;20(1):91-100.
2003: Laura J Schild; Rao L Divi; Frederick A Beland; Mona I Churchwell; Daniel R Doerge; Gonçalo Gamboa da Costa; M Matilde Marques; Miriam C Poirier
Formation of tamoxifen-DNA adducts in multiple organs of adult female cynomolgus monkeys dosed with tamoxifen for 30 days.
Cancer research 2003;63(18):5999-6003.
2003: Shinya Shibutani; Naomi Suzuki; Y R Santosh Laxmi; Laura J Schild; Rao L Divi; Arthur P Grollman; Miriam C Poirier
Identification of tamoxifen-DNA adducts in monkeys treated with tamoxifen.
Cancer research 2003;63(15):4402-6.
2003: Miriam C Poirier; Laura J Schild
The genotoxicity of tamoxifen: extent and consequences, Kona, Hawaii, January 23, 2003.
Mutagenesis 2003;18(4):395-9.
2003: Miriam C Poirier; Rao L Divi; Lena Al-Harthi; Ofelia A Olivero; Vi Nguyen; Brettania Walker; Alan L Landay; Vernon E Walker; Man E Charurat; William A Blattner
Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers.
Journal of acquired immune deficiency syndromes (1999) 2003;33(2):175-83.
2002: Rao L Divi; Frederick A Beland; Peter P Fu; Linda S Von Tungeln; Bernadette Schoket; Johanna Eltz Camara; Monica Ghei; Nathaniel Rothman; Rashmi Sinha; Miriam C Poirier
Highly sensitive chemiluminescence immunoassay for benzo[a]pyrene-DNA adducts: validation by comparison with other methods, and use in human biomonitoring.
Carcinogenesis 2002;23(12):2043-9.
2002: Hilde E van Gijssel; Rao L Divi; Ofelia A Olivero; Mark J Roth; Guo-Qing Wang; Sanford M Dawsey; Paul S Albert; You-Lin Qiao; Philip R Taylor; Zhi-Wei Dong; Jeffrey A Schrager; David E Kleiner; Miriam C Poirier
Semiquantitation of polycyclic aromatic hydrocarbon-DNA adducts in human esophagus by immunohistochemistry and the automated cellular imaging system.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(12):1622-9.
2002: Ofelia A Olivero; Juan J Fernandez; Brendan Antiochos; Jessica L Wagner; Marisa E St Claire; Miriam C Poirier
Transplacental genotoxicity of combined antiretroviral nucleoside analogue therapy in Erythrocebus patas monkeys.
Journal of acquired immune deficiency syndromes (1999) 2002;29(4):323-9.
2001: Aizen J Marrogi; Mohammed A Khan; Hilde E van Gijssel; Judith A Welsh; H Rahim; Anthony Demetris; K V Kowdley; S Perwez Hussain; jagadeesan nair; Helmut Bartsch; N Okby; Miriam C Poirier; KG Ishak; Curtis C Harris
Oxidative stress and p53 mutations in the carcinogenesis of iron overload-associated hepatocellular carcinoma.
Journal of the National Cancer Institute 2001;93(21):1652-5.
2001: Mariana Gerschenson; V T Nguyen; M C St Claire; Steven W Harbaugh; Jeffrey W Harbaugh; Laurie A Proia; Miriam C Poirier
Chronic stavudine exposure induces hepatic mitochondrial toxicity in adult Erythrocebus patas monkeys.
Journal of human virology 2001;4(6):335-42.
2001: Rao L Divi; Yvonne P Dragan; Henry C Pitot; Miriam C Poirier
Immunohistochemical localization and semi-quantitation of hepatic tamoxifen-DNA adducts in rats exposed orally to tamoxifen.
Carcinogenesis 2001;22(10):1693-9.
2001: Mariana Gerschenson; C Y Paik; E L Gaukler; Bhalchandra A Diwan; Miriam C Poirier
Cisplatin exposure induces mitochondrial toxicity in pregnant rats and their fetuses.
Reproductive toxicology (Elmsford, N.Y.) 2001;15(5):525-31.
2001: Ofelia A Olivero; M K Reddy; S M Pietras; Miriam C Poirier
Plasma drug levels compared with DNA incorporation of 3'-azido-3'-deoxythymidine (AZT) in adult cynomolgus (Macaca fascicularis) monkeys.
Experimental biology and medicine (Maywood, N.J.) 2001;226(5):446-9.
2000: Quanxin Meng; Dale M Walker; Ofelia A Olivero; X Shi; Brendan Antiochos; Miriam C Poirier; Vernon E Walker
Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12667-71.
2000: Mariana Gerschenson; Miriam C Poirier
Fetal patas monkeys sustain mitochondrial toxicity as a result of in utero zidovudine exposure.
Annals of the New York Academy of Sciences 2000;918():269-81.
2000: Ofelia A Olivero; Gene M Shearer; Claire Chougnet; Andrea Kovacs; R Baker; Alice Stek; M M Khoury; Miriam C Poirier
Incorporation of zidovudine into cord blood DNA of infants and peripheral blood DNA of their HIV-1-positive mothers.
Annals of the New York Academy of Sciences 2000;918():262-8.
2000: Mark J Roth; Sanford M Dawsey; G Wang; Joseph A Tangrea; B Zhou; D Luke Ratnasinghe; Karen Woodson; Ofelia A Olivero; Miriam C Poirier; Bonnie L Frye; Philip R Taylor; Ainsley Weston
Association between GSTM1*0 and squamous dysplasia of the esophagus in the high risk region of Linxian, China.
Cancer letters 2000;156(1):73-81.
2000: E L Ewings; Mariana Gerschenson; Marisa C St Claire; Kunio Nagashima; B Skopets; Steven W Harbaugh; Jeffrey W Harbaugh; Miriam C Poirier
Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria.
Journal of acquired immune deficiency syndromes (1999) 2000;24(2):100-5.
2000: Mariana Gerschenson; S W Erhart; C Y Paik; Marisa C St Claire; Kunio Nagashima; B Skopets; Steven W Harbaugh; Jeffrey W Harbaugh; W Quan; Miriam C Poirier
Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3'-azido-3'-deoxythymidine.
AIDS research and human retroviruses 2000;16(7):635-44.
2000: Aneta Bialkowska; Karol Bialkowski; Mariana Gerschenson; Bhalchandra A Diwan; A B Jones; Ofelia A Olivero; Miriam C Poirier; Lucy M Anderson; Kazimierz S Kasprzak; MA Sipowicz
Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT).
Carcinogenesis 2000;21(5):1059-62.
2000: William Slikker; Ofelia A Olivero; Patterson Tucker; Miriam C Poirier
Potential toxicities of HIV therapeutics in the developing infant.
Teratology 2000;61(5):397-8.
2000: Bhalchandra A Diwan; Ofelia A Olivero; Miriam C Poirier
Absence of structural or functional alterations in male and female reproductive organs of F1 and F2 generations derived from female mice exposed to 3'-azido-3'-deoxythymidine during pregnancy.
Toxicology letters 2000;115(1):9-15.
2000: Q Meng; T Su; Ofelia A Olivero; Miriam C Poirier; X Shi; X Ding; Vernon E Walker
Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine.
Toxicological sciences : an official journal of the Society of Toxicology 2000;54(2):322-9.
2000: Miriam C Poirier; Regina M Santella; A Weston
Carcinogen macromolecular adducts and their measurement.
Carcinogenesis 2000;21(3):353-9.
1999: Miriam C Poirier; Patterson Tucker; W Slikker; Ofelia A Olivero
Incorporation of 3'-azido-3'-deoxythymidine (AZT) into fetal DNA and fetal tissue distribution of drug after infusion of pregnant late-term rhesus macaques with a human-equivalent AZT dose.
Journal of acquired immune deficiency syndromes (1999) 1999;22(5):477-83.
1999: Bhalchandra A Diwan; CW Riggs; Daniel Logsdon; Diana C Haines; Ofelia A Olivero; Jerry M Rice; S H Yuspa; Miriam C Poirier; Lucy M Anderson
Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice.
Toxicology and applied pharmacology 1999;161(1):82-99.
1999: HE Sussman; Ofelia A Olivero; Quanxin Meng; S M Pietras; Miriam C Poirier; J Patrick O'Neill; Barry A Finette; Michael J Bauer; Vernon E Walker
Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT.
Mutation research 1999;429(2):249-59.
1999: Rao L Divi; Martin R Osborne; Alan Hewer; David H Phillips; Miriam C Poirier
Tamoxifen-DNA adduct formation in rat liver determined by immunoassay and 32P-postlabeling.
Cancer research 1999;59(19):4829-33.
1999: Bernadette Schoket; Miriam C Poirier; G Mayer; G Török; A Kolozsi-Ringelhann; G Bognár; William L Bigbee; I Vincze
Biomonitoring of human genotoxicity induced by complex occupational exposures.
Mutation research 1999;445(2):193-203.
1999: Ofelia A Olivero; R Parikka; Miriam C Poirier; Kirsi Vähäkangas
3'-azido-3'-deoxythymidine (AZT) transplacental perfusion kinetics and DNA incorporation in normal human placentas perfused with AZT.
Mutation research 1999;428(1-2):41-7.
1999: Ofelia A Olivero; Gene M Shearer; Claire Chougnet; Andrea Kovacs; Alan L Landay; R Baker; Alice Stek; M M Khoury; Laurie A Proia; Harold A Kessler; Beverly E Sha; R E Tarone; Miriam C Poirier
Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero.
AIDS (London, England) 1999;13(8):919-25.
1999: Frederick A Beland; Daniel R Doerge; Mona I Churchwell; Miriam C Poirier; Bernadette Schoket; M Matilde Marques
Synthesis, characterization, and quantitation of a 4-aminobiphenyl-DNA adduct standard.
Chemical research in toxicology 1999;12(1):68-77.
1998: Z Zhang; Bhalchandra A Diwan; Lucy M Anderson; Daniel Logsdon; Ofelia A Olivero; Diana C Haines; Jerry M Rice; Stuart H Yuspa; Miriam C Poirier
Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3'-azido-2',3'-dideoxythymidine.
Molecular carcinogenesis 1998;23(1):45-51.
1998: Miriam C Poirier; Ainsley Weston; Bernadette Schoket; H Shamkhani; CF Pan; Melissa A McDiarmid; B G Scott; D P Deeter; J M Heller; David Jacobson-Kram; Nathaniel Rothman
Biomonitoring of United States Army soldiers serving in Kuwait in 1991.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(6):545-51.
1997: Ofelia A Olivero; Lucy M Anderson; Bhalchandra A Diwan; Diana C Haines; Steven W Harbaugh; T J Moskal; A B Jones; Jerry M Rice; CW Riggs; Daniel Logsdon; Stuart H Yuspa; Miriam C Poirier
Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.
Journal of the National Cancer Institute 1997;89(21):1602-8.
1997: Z Zhang; Miriam C Poirier
Cisplatin-DNA adduct determination in the hepatic albumin gene as compared to whole genomic DNA.
Chemical research in toxicology 1997;10(9):971-7.
1997: Ofelia A Olivero; P K Chang; D M Lopez-Larraza; M C Semino-Mora; Miriam C Poirier
Preferential formation and decreased removal of cisplatin-DNA adducts in Chinese hamster ovary cell mitochondrial DNA as compared to nuclear DNA.
Mutation research 1997;391(1-2):79-86.
1997: Miriam C Poirier
DNA adducts as exposure biomarkers and indicators of cancer risk.
Environmental health perspectives 1997;105 Suppl 4():907-12.
1997: Miriam C Poirier; Frederick A Beland
Aromatic amine DNA adduct formation in chronically-exposed mice: considerations for human comparison.
Mutation research 1997;376(1-2):177-84.
1997: A J Giurgiovich; Lucy M Anderson; A B Jones; Lee F Dove; T J Moskal; Jerry M Rice; Ofelia A Olivero; Miriam C Poirier
Transplacental cisplatin exposure induces persistent fetal mitochondrial and genomic DNA damage in patas monkeys.
Reproductive toxicology (Elmsford, N.Y.) 1997;11(1):95-100.
1997: A J Giurgiovich; Bhalchandra A Diwan; Ofelia A Olivero; Lucy M Anderson; Jerry M Rice; Miriam C Poirier
Elevated mitochondrial cisplatin-DNA adduct levels in rat tissues after transplacental cisplatin exposure.
Carcinogenesis 1997;18(1):93-6.
1996: Miriam C Poirier; Ainsley Weston
Human DNA adduct measurements: state of the art.
Environmental health perspectives 1996;104 Suppl 5():883-93.
1996: A J Giurgiovich; Bhalchandra A Diwan; K B Lee; Lucy M Anderson; Jerry M Rice; Miriam C Poirier
Cisplatin-DNA adduct formation in maternal and fetal rat tissues after transplacental cisplatin exposure.
Carcinogenesis 1996;17(8):1665-9.
1995: Miriam C Poirier; N F Fullerton; B A Smith; F A Beland
DNA adduct formation and tumorigenesis in mice during the chronic administration of 4-aminobiphenyl at multiple dose levels.
Carcinogenesis 1995;16(12):2917-21.
1995: Nathaniel Rothman; Peter G Shields; Miriam C Poirier; A M Harrington; D Patrick Ford; Paul T Strickland
The impact of glutathione s-transferase M1 and cytochrome P450 1A1 genotypes on white-blood-cell polycyclic aromatic hydrocarbon-DNA adduct levels in humans.
Molecular carcinogenesis 1995;14(1):63-8.
1995: D H Kang; Nathaniel Rothman; Miriam C Poirier; A Greenberg; C H Hsu; Brian S Schwartz; M E Baser; John Groopman; Ainsley Weston; Paul T Strickland
Interindividual differences in the concentration of 1-hydroxypyrene-glucuronide in urine and polycyclic aromatic hydrocarbon-DNA adducts in peripheral white blood cells after charbroiled beef consumption.
Carcinogenesis 1995;16(5):1079-85.
1995: Ofelia A Olivero; C Semino; A Kassim; D M Lopez-Larraza; Miriam C Poirier
Preferential binding of cisplatin to mitochondrial DNA of Chinese hamster ovary cells.
Mutation research 1995;346(4):221-30.
1995: Bernadette Schoket; Miriam C Poirier; I Vincze
Biomonitoring of genotoxic exposure in aluminium plant workers by determination of DNA adducts in human peripheral blood lymphocytes.
The Science of the total environment 1995;163(1-3):153-63.
1994: Ofelia A Olivero; F A Beland; N F Fullerton; Miriam C Poirier
Vaginal epithelial DNA damage and expression of preneoplastic markers in mice during chronic dosing with tumorigenic levels of 3'-azido-2',3'-dideoxythymidine.
Cancer research 1994;54(23):6235-42.
1994: Miriam C Poirier; F A Beland
DNA adduct measurements and tumor incidence during chronic carcinogen exposure in rodents.
Environmental health perspectives 1994;102 Suppl 6():161-5.
1994: H Shamkhani; Lucy M Anderson; Cassandra Henderson; T J Moskal; C D Runowicz; L F Dove; A B Jones; Stephen G Chaney; Jerry M Rice; Miriam C Poirier
DNA adducts in human and patas monkey maternal and fetal tissues induced by platinum drug chemotherapy.
Reproductive toxicology (Elmsford, N.Y.) 1994;8(3):207-16.
1993: Bernadette Schoket; W A Doty; I Vincze; Paul T Strickland; G M Ferri; Giorgio Assennato; Miriam C Poirier
Increased sensitivity for determination of polycyclic aromatic hydrocarbon-DNA adducts in human DNA samples by dissociation-enhanced lanthanide fluoroimmunoassay (DELFIA).
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1993;2(4):349-53.
1993: Nathaniel Rothman; A Correa-Villaseñor; D Patrick Ford; Miriam C Poirier; R Haas; J A Hansen; T O'Toole; Paul T Strickland
Contribution of occupation and diet to white blood cell polycyclic aromatic hydrocarbon-DNA adducts in wildland firefighters.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1993;2(4):341-7.
1993: Miriam C Poirier
Antisera specific for carcinogen-DNA adducts and carcinogen-modified DNA: applications for detection of xenobiotics in biological samples.
Mutation research 1993;288(1):31-8.
1993: S Gupta-Burt; H Shamkhani; Eddie Reed; Robert E Tarone; Carmen J Allegra; L H Pai; Miriam C Poirier
Relationship between patient response in ovarian and breast cancer and platinum drug-DNA adduct formation.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1993;2(3):229-34.
1993: Cassandra Henderson; G Elia; D Garfinkel; Miriam C Poirier; H Shamkhani; C D Runowicz
Platinum chemotherapy during pregnancy for serous cystadenocarcinoma of the ovary.
Gynecologic oncology 1993;49(1):92-4.
1993: Bernadette Schoket; David H Phillips; Miriam C Poirier; I Vincze
DNA adducts in peripheral blood lymphocytes from aluminum production plant workers determined by 32P-postlabeling and enzyme-linked immunosorbent assay.
Environmental health perspectives 1993;99():307-9.
1993: Nathaniel Rothman; Miriam C Poirier; R A Haas; A Correa-Villasenor; P Ford; J A Hansen; T O'Toole; Paul T Strickland
Association of PAH-DNA adducts in peripheral white blood cells with dietary exposure to polyaromatic hydrocarbons.
Environmental health perspectives 1993;99():265-7.
1993: Ainsley Weston; Elise D Bowman; Peter G Shields; G E Trivers; Miriam C Poirier; Regina Santella; D K Manchester
Detection of polycyclic aromatic hydrocarbon-DNA adducts in human lung.
Environmental health perspectives 1993;99():257-9.
1993: Giorgio Assennato; G M Ferri; M S Tockman; Miriam C Poirier; Bernadette Schoket; A Porro; V Corrado; Paul T Strickland
Biomarkers of carcinogen exposure and cancer risk in a coke plant.
Environmental health perspectives 1993;99():237-9.
1993: Miriam C Poirier; Eddie Reed; H Shamkhani; Robert E Tarone; S Gupta-Burt
Platinum drug-DNA interactions in human tissues measured by cisplatin-DNA enzyme-linked immunosorbent assay and atomic absorbance spectroscopy.
Environmental health perspectives 1993;99():149-54.
1993: Ofelia A Olivero; Miriam C Poirier
Preferential incorporation of 3'-azido-2',3'-dideoxythymidine into telomeric DNA and Z-DNA-containing regions of Chinese hamster ovary cells.
Molecular carcinogenesis 1993;8(2):81-8.
1992: Miriam C Poirier; F A Beland
DNA adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: implications for DNA adduct-based human cancer risk assessment.
Chemical research in toxicology 1992;5(6):749-55.
1992: L H Pai; S M Swain; D J Venzon; Eddie Reed; Miriam C Poirier; S Gupta-Burt; A M Denicoff; Carmen J Allegra
Therapy of patients with metastatic breast cancer with 5-fluorouracil, leucovorin and carboplatin.
Anti-cancer drugs 1992;3(5):463-9.
1992: Miriam C Poirier; Eddie Reed; C L Litterst; D Katz; S Gupta-Burt
Persistence of platinum-ammine-DNA adducts in gonads and kidneys of rats and multiple tissues from cancer patients.
Cancer research 1992;52(1):149-53.
1992: Miriam C Poirier; H Shamkhani; Eddie Reed; Robert E Tarone; S Gupta-Burt
DNA adducts induced by platinum drug chemotherapeutic agents in human tissues.
Progress in clinical and biological research 1992;374():197-212.
1991: Miriam C Poirier; N F Fullerton; T Kinouchi; B A Smith; F A Beland
Comparison between DNA adduct formation and tumorigenesis in livers and bladders of mice chronically fed 2-acetylaminofluorene.
Carcinogenesis 1991;12(5):895-900.
1991: Miriam C Poirier; Ainsley Weston
DNA adduct determination in humans.
Progress in clinical and biological research 1991;372():205-18.
1990: Eddie Reed; S Gupta-Burt; C L Litterst; Miriam C Poirier
Characterization of the DNA damage recognized by an antiserum elicited against cis-diamminedichloroplatinum (II)-modified DNA.
Carcinogenesis 1990;11(12):2117-21.
1990: Miriam C Poirier; N F Fullerton; E D Patterson; F A Beland
DNA adduct formation and removal in hepatic chromatin fractions from rats chronically fed 2-acetylaminofluorene.
Carcinogenesis 1990;11(8):1343-7.
1990: Nathaniel Rothman; Miriam C Poirier; M E Baser; J A Hansen; C Gentile; Elise D Bowman; Paul T Strickland
Formation of polycyclic aromatic hydrocarbon-DNA adducts in peripheral white blood cells during consumption of charcoal-broiled beef.
Carcinogenesis 1990;11(7):1241-3.
1990: Ofelia A Olivero; C Semino; Miriam C Poirier
Localization of DNA adducts induced by N-acetoxy-N-2-acetylaminofluorene in Chinese hamster ovary cells using electron microscopy and colloidal gold.
Genes, chromosomes & cancer 1990;2(2):130-6.
1990: Henry Hennings; R A Shores; Miriam C Poirier; Eddie Reed; Robert E Tarone; Stuart H Yuspa
Enhanced malignant conversion of benign mouse skin tumors by cisplatin.
Journal of the National Cancer Institute 1990;82(10):836-40.
1990: Eddie Reed; Y Ostchega; Seth M Steinberg; Stuart H Yuspa; R C Young; R F Ozols; Miriam C Poirier
Evaluation of platinum-DNA adduct levels relative to known prognostic variables in a cohort of ovarian cancer patients.
Cancer research 1990;50(8):2256-60.
1990: Ofelia A Olivero; H Huitfeldt; Miriam C Poirier
Chromosome site-specific immunohistochemical detection of DNA adducts in N-acetoxy-2-acetylaminofluorene--exposed Chinese hamster ovary cells.
Molecular carcinogenesis 1990;3(1):37-43.
1990: Miriam C Poirier; Ainsley Weston; S Gupta-Burt; Eddie Reed
Measurement of DNA adducts by immunoassays.
Basic life sciences 1990;53():1-11.
1990: R J Parker; Miriam C Poirier; F Bostick-Bruton; J Vionnet; Vilhelm A Bohr; Eddie Reed
Peripheral blood leukocytes as a surrogate marker for cisplatin drug resistance: studies of adduct levels and the repair gene ERCC1.
Basic life sciences 1990;53():251-61.
1989: S H Liou; David Jacobson-Kram; Miriam C Poirier; D Nguyen; Paul T Strickland; M S Tockman
Biological monitoring of fire fighters: sister chromatid exchange and polycyclic aromatic hydrocarbon-DNA adducts in peripheral blood cells.
Cancer research 1989;49(17):4929-35.
1989: Miriam C Poirier; F A Beland; F H Deal; James A Swenberg
DNA adduct formation and removal in specific liver cell populations during chronic dietary administration of 2-acetylaminofluorene.
Carcinogenesis 1989;10(6):1143-5.
1989: Miriam C Poirier; S H Liou; Eddie Reed; Paul T Strickland; M S Tockman
Determination of carcinogen-DNA adducts by immunoassay.
Journal of UOEH 1989;11 Suppl():353-67.
1989: Ainsley Weston; D K Manchester; Miriam C Poirier; J S Choi; G E Trivers; Dean L Mann; Curtis C Harris
Derivative fluorescence spectral analysis of polycyclic aromatic hydrocarbon-DNA adducts in human placenta.
Chemical research in toxicology 1989;2(2):104-8.
1988: Eddie Reed; R F Ozols; Robert E Tarone; Stuart H Yuspa; Miriam C Poirier
The measurement of cisplatin-DNA adduct levels in testicular cancer patients.
Carcinogenesis 1988;9(10):1909-11.
1988: Ainsley Weston; James Willey; D K Manchester; V L Wilson; Bernard Brooks; J S Choi; Miriam C Poirier; G E Trivers; M J Newman; Dean L Mann
Dosimeters of human exposure to carcinogens: polycyclic aromatic hydrocarbon-macromolecular adducts.
IARC scientific publications 1988;(89):181-9.
1988: Miriam C Poirier; Merrill J Egorin; A M Fichtinger-Schepman; Stuart H Yuspa; Eddie Reed
DNA adducts of cisplatin and carboplatin in tissues of cancer patients.
IARC scientific publications 1988;(89):313-20.