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Katerina Politi

Research Profile

Living Beings

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Chemicals & Drugs

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Publications

TOP 3
Ho-June Lee; Shiva Malek; Mark Merchant; Valentina Pirazzoli; Katerina Politi; Gabriele Schaefer; Lily Shao; Steve Sideris; Savita Ubhayakar; Robert L Yauch; Xiaofen Ye; Emily Chan; Timothy P Heffron; Hank La; Jeff Settleman
Noncovalent wild-type-sparing inhibitors of EGFR T790M.
Ken Takezawa; Valentina Pirazzoli; Katerina Politi; Gregory J Riely; Xiaoling Song; Paula J Spitzler; Maria E Arcila; Elisa de Stanchina; Yelena Y Janjigian; Mark G Kris; Marc Ladanyi; Mary Ann Melnick; Vincent A Miller; Caroline A Nebhan; Kadoaki Ohashi; William Pao
HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation.
Ayumu Taguchi; Harold E Varmus; Chee-Hong Wong; Qing Zhang; Alice Chin; Ronald A DePinho; Daniela M Dinulescu; Vitor M Faça; Adi F Gazdar; Gary Goodman; Karen Kelly-Spratt; Christopher J Kemp; Raju Kucherlapati; William W Lockwood; Kwon-Sik Park; Sharon J Pitteri; Katerina Politi; Julien Sage; Samir M Hanash
Lung cancer signatures in plasma based on proteome profiling of mouse tumor models.

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All Publications

2013: Ho-June Lee; Shiva Malek; Mark Merchant; Valentina Pirazzoli; Katerina Politi; Gabriele Schaefer; Lily Shao; Steve Sideris; Savita Ubhayakar; Robert L Yauch; Xiaofen Ye; Emily Chan; Timothy P Heffron; Hank La; Jeff Settleman
Noncovalent wild-type-sparing inhibitors of EGFR T790M.
Cancer discovery 2013;3(2):168-81.
2012: Ken Takezawa; Valentina Pirazzoli; Katerina Politi; Gregory J Riely; Xiaoling Song; Paula J Spitzler; Maria E Arcila; Elisa de Stanchina; Yelena Y Janjigian; Mark G Kris; Marc Ladanyi; Mary Ann Melnick; Vincent A Miller; Caroline A Nebhan; Kadoaki Ohashi; William Pao
HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation.
Cancer discovery 2012;2(10):922-33.
2011: Ayumu Taguchi; Harold E Varmus; Chee-Hong Wong; Qing Zhang; Alice Chin; Ronald A DePinho; Daniela M Dinulescu; Vitor M Faça; Adi F Gazdar; Gary Goodman; Karen Kelly-Spratt; Christopher J Kemp; Raju Kucherlapati; William W Lockwood; Kwon-Sik Park; Sharon J Pitteri; Katerina Politi; Julien Sage; Samir M Hanash
Lung cancer signatures in plasma based on proteome profiling of mouse tumor models.
Cancer cell 2011;20(3):289-99.
2010: Katerina Politi; Pang-Dian Fan; Ronglai Shen; Maureen Zakowski; Harold Varmus
Erlotinib resistance in mouse models of epidermal growth factor receptor-induced lung adenocarcinoma.
Disease models & mechanisms 2010;3(1-2):111-9.
2008: George Trimis; Ioulia Chatzistamou; Katerina Politi; Hippokratis Kiaris; Athanasios G Papavassiliou
Expression of p21waf1/Cip1 in stromal fibroblasts of primary breast tumors.
Human molecular genetics 2008;17(22):3596-600.
2008: Katrina Podsypanina; Katerina Politi; Levi J Beverly; Harold Varmus
Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(13):5242-7.
2008: Qing Zhang; Rajasree Menon; Eric W Deutsch; Sharon J Pitteri; Vitor M Faca; Hong Wang; Lisa F Newcomb; Ronald A DePinho; Nabeel Bardeesy; Daniela M Dinulescu; Kenneth E Hung; Raju Kucherlapati; Tyler Jacks; Katerina Politi; Ruedi Aebersold; Gilbert S Omenn; David States; Samir M Hanash
A mouse plasma peptide atlas as a resource for disease proteomics.
Genome biology 2008;9(6):R93.
2007: Yixuan Gong; Romel Somwar; Katerina Politi; Marissa N Balak; Juliann Chmielecki; Xuejun Jiang; William Pao
Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas.
PLoS medicine 2007;4(10):e294.
2007: Lucia Regales; Marissa N Balak; Yixuan Gong; Katerina Politi; Ayana Sawai; Carl Le; Jason A Koutcher; David B Solit; Neal Rosen; Maureen F Zakowski; William Pao
Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors.
PloS one 2007;2(8):e810.
2006: Gregory J Riely; Katerina Politi; Vincent A Miller; William Pao
Update on epidermal growth factor receptor mutations in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7232-41.
2006: David C Christiani; William Pao; James DeMartini; R Ilona Linnoila; Alvin M Malkinson; Amir Onn; Katerina Politi; Michael Sharp; Kwok-Kin Wong; Kwok Kim
BAC consensus conference, November 4-6, 2004: epidemiology, pathogenesis, and preclinical models.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(9 Suppl):S2-7.
2006: Christos Cheretis; Frank Dietrich; Ioulia Chatzistamou; Katerina Politi; Eirini Angelidou; Hippokratis Kiaris; Souren Mkrtchian; Helen Koutselini
Expression of ERp29, an endoplasmic reticulum secretion factor in basal-cell carcinoma.
The American Journal of dermatopathology 2006;28(5):410-2.
2006: Apostolos Klinakis; Matthias Szabolcs; Katerina Politi; Hippokratis Kiaris; Spyros Artavanis-Tsakonas; Argiris Efstratiadis
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9262-7.
2006: Katerina Politi; Maureen F Zakowski; Pang-Dian Fan; Emily A Schonfeld; William Pao; Harold Varmus
Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors.
Genes & development 2006;20(11):1496-510.
2005: William Pao; Vincent A Miller; Katerina Politi; Gregory J Riely; Romel Somwar; Maureen F Zakowski; Mark G Kris; Harold Varmus
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain.
PLoS medicine 2005;2(3):e73.
2005: Harold Varmus; William Pao; Katerina Politi; Katrina Podsypanina; Yi-Chieh Nancy Du
Oncogenes come of age.
Cold Spring Harbor symposia on quantitative biology 2005;70():1-9.
2004: Katerina Politi; Nikki Feirt; Jan Kitajewski
Notch in mammary gland development and breast cancer.
Seminars in cancer biology 2004;14(5):341-7.
2004: William Pao; Vincent A Miller; Maureen F Zakowski; Jennifer Doherty; Katerina Politi; Inderpal S Sarkaria; Bhuvanesh Singh; Robert T Heelan; Valerie W Rusch; Lucinda Fulton; Elaine R Mardis; Doris Kupfer; Richard Wilson; Mark G Kris; Harold Varmus
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(36):13306-11.
2004: Hippokratis Kiaris; Katerina Politi; Lisa M Grimm; Matthias Szabolcs; Peter Fisher; Argiris Efstratiadis; Spyros Artavanis-Tsakonas
Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium.
The American journal of pathology 2004;165(2):695-705.
2004: Katerina Politi; Ana Kljuic; Matthias Szabolcs; Peter Fisher; Thomas Ludwig; Argiris Efstratiadis
'Designer' tumors in mice.
Oncogene 2004;23(8):1558-65.
2004: Katerina Politi; Matthias Szabolcs; Peter Fisher; Ana Kljuic; Thomas Ludwig; Argiris Efstratiadis
A mouse model of uterine leiomyosarcoma.
The American journal of pathology 2004;164(1):325-36.
2002: Shouhong Xuan; Tadahiro Kitamura; Jun Nakae; Katerina Politi; Yoshiaki Kido; Peter E Fisher; Manrico Morroni; Saverio Cinti; Morris F White; Pedro L Herrera; Domenico Accili; Argiris Efstratiadis
Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor.
The Journal of clinical investigation 2002;110(7):1011-9.
1996: G Scita; N Darwiche; E Greenwald; M Rosenberg; Katerina Politi; LUIGI DE LUCA
Retinoic acid down-regulation of fibronectin and retinoic acid receptor alpha proteins in NIH-3T3 cells. Blocks of this response by ras transformation.
The Journal of biological chemistry 1996;271(11):6502-8.