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Leon Poller

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Leon Poller; S Ibrahim; Jørgen Jespersen; A Pattison
Coagulometer international sensitivity index (ISI) derivation, a rapid method using the prothrombin time/international normalized ratio (PT/INR) Line: a multicenter study.
Leon Poller; Jørgen Jespersen; S Ibrahim
Artificially depleted plasmas are not necessarily commutable with native patient plasmas for International Sensitivity Index calibration and International Normalized Ratio derivation: a rebuttal.
Leon Poller; Jørgen Jespersen; Trevor Baglin; Campbell Cowan; Jennifer George; Saied A Ibrahim
Application of the UK NHS Improvement Anticoagulation Commissioning Support Document for 'safety indicators' in atrial fibrillation. Results of the European Action on Anticoagulation study.

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All Publications

2012: Leon Poller; S Ibrahim; Jørgen Jespersen; A Pattison
Coagulometer international sensitivity index (ISI) derivation, a rapid method using the prothrombin time/international normalized ratio (PT/INR) Line: a multicenter study.
Journal of thrombosis and haemostasis : JTH 2012;10(7):1379-84.
2012: Leon Poller; Jørgen Jespersen; S Ibrahim
Artificially depleted plasmas are not necessarily commutable with native patient plasmas for International Sensitivity Index calibration and International Normalized Ratio derivation: a rebuttal.
Journal of thrombosis and haemostasis : JTH 2012;10(6):1197-8; author reply 1198-200.
2012: Leon Poller; Jørgen Jespersen; Trevor Baglin; Campbell Cowan; Jennifer George; Saied A Ibrahim
Application of the UK NHS Improvement Anticoagulation Commissioning Support Document for 'safety indicators' in atrial fibrillation. Results of the European Action on Anticoagulation study.
Journal of clinical pathology 2012;65(5):452-6.
2011: Leon Poller; Saied Ibrahim; Jørgen Jespersen; Albert Pattison
INR derivation with the PT/INR Line simplified using a spreadsheet from the world wide web.
Journal of clinical pathology 2011;64(10):930-2.
2011: Saied A Ibrahim; Jørgen Jespersen; Albert Pattison; Leon Poller
Evaluation of European Concerted Action on Anticoagulation lyophilized plasmas for INR derivation using the PT/INR line.
American journal of clinical pathology 2011;135(5):732-40.
2011: Leon Poller; S Ibrahim; Michelle Keown; A Pattison; Jørgen Jespersen
The prothrombin time/international normalized ratio (PT/INR) Line: derivation of local INR with commercial thromboplastins and coagulometers--two independent studies.
Journal of thrombosis and haemostasis : JTH 2011;9(1):140-8.
2010: Leon Poller; Saied Ibrahim; Michelle Keown; Albert Pattison; Jørgen Jespersen
Simplified method for international normalized ratio (INR) derivation based on the prothrombin time/INR line: an international study.
Clinical chemistry 2010;56(10):1608-17.
2009: Leon Poller; Michelle Keown; Saied Ibrahim; Gordon Lowe; Marco Moia; Alexander G Turpie; Christopher Roberts; A M H P van den Besselaar; Felix J M van der Meer; Armando Tripodi; Gualtiero Palareti; Caroline Shiach; Stirling Bryan; Meyer Samama; Michael Burgess-Wilson; Anthony Heagerty; Peter Maccallum; David Wright; Jørgen Jespersen
A multicentre randomised assessment of the DAWN AC computer-assisted oral anticoagulant dosage program.
Thrombosis and haemostasis 2009;101(3):487-94.
2009: Leon Poller
Precision and accuracy of CoaguChek S and XS monitors: the need for external quality assessment.
Thrombosis and haemostasis 2009;101(3):419-21.
2008: Leon Poller; Michelle Keown; Saied Ibrahim; Gordon Lowe; Marco Moia; Alexander G Turpie; Christopher Roberts; A M H P van den Besselaar; Felix J M van der Meer; Armando Tripodi; Gualtiero Palareti; Jørgen Jespersen
A multicentre randomised clinical endpoint study of PARMA 5 computer-assisted oral anticoagulant dosage.
British journal of haematology 2008;143(2):274-83.
2008: Leon Poller; Michelle Keown; S Ibrahim; G Lowe; M Moia; A G Turpie; C Roberts; A M H P van den Besselaar; Felix J M van der Meer; Armando Tripodi; G Palareti; Caroline Shiach; Stirling Bryan; M Samama; M Burgess-Wilson; A Heagerty; P Maccallum; D Wright; Jørgen Jespersen
An international multicenter randomized study of computer-assisted oral anticoagulant dosage vs. medical staff dosage.
Journal of thrombosis and haemostasis : JTH 2008;6(6):935-43.
2007: Leon Poller; Michelle Keown; S Ibrahim; A M H P van den Besselaar; C Roberts; K Stevenson; Armando Tripodi; A Pattison; Jørgen Jespersen
Comparison of local International Sensitivity Index calibration and 'Direct INR' methods in correction of locally reported International Normalized Ratios: an international study.
Journal of thrombosis and haemostasis : JTH 2007;5(5):1002-9.
2006: Piet Meijer; Cornelis Kluft; Leon Poller; Felix J M van der Meer; Michelle Keown; Saied Ibrahim; A M H P van den Besselaar; Armando Tripodi; Jørgen Jespersen
A national field study of quality assessment of CoaguChek point-of-care testing prothrombin time monitors.
American journal of clinical pathology 2006;126(5):756-61.
2006: Leon Poller; Michelle Keown; Saied A Ibrahim; Felix J M van der Meer; A M H P van den Besselaar; Armando Tripodi; Jørgen Jespersen; Pieter Meijer; Cornelis Kluft
Quality assessment of CoaguChek point-of-care prothrombin time monitors: comparison of the European community-approved procedure and conventional external quality assessment.
Clinical chemistry 2006;52(10):1843-7.
2005: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Caroline Shiach; Jørgen Jespersen
European Concerted Action on Anticoagulation. A multicentre calibration study of WHO international reference preparations for thromboplastin, rabbit (RBT/90) and human (rTF/95).
Journal of clinical pathology 2005;58(6):667-9.
2004: A M H P van den Besselaar; TW Barrowcliffe; L L Houbouyan-Réveillard; Jørgen Jespersen; M Johnston; Leon Poller; Armando Tripodi
Guidelines on preparation, certification, and use of certified plasmas for ISI calibration and INR determination.
Journal of thrombosis and haemostasis : JTH 2004;2(11):1946-53.
2004: Jack Ansell; Jack Hirsh; Leon Poller; Henry Bussey; Alan Jacobson; Elaine M Hylek
The pharmacology and management of the vitamin K antagonists: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Chest 2004;126(3 Suppl):204S-233S.
2004: A M H P van den Besselaar; Leon Poller; A Tripodi
Definition of the International Normalized Ratio (INR) and its consequences for the calibration procedure of thromboplastin preparations: a rebuttal.
Journal of thrombosis and haemostasis : JTH 2004;2(8):1490-1; reply 1492-4.
2004: Leon Poller
International Normalized Ratios (INR): the first 20 years.
Journal of thrombosis and haemostasis : JTH 2004;2(6):849-60.
2004: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Caroline Shiach; Jørgen Jespersen
European concerted action on anticoagulation. Quality assessment of the CoaguChek Mini and TAS PT-NC point-of-care whole-blood prothrombin time monitors.
Clinical chemistry 2004;50(3):537-44.
2003: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Caroline Shiach; Jørgen Jespersen
European Concerted Action on Anticoagulation. Correction of displayed international normalized ratio on two point-of-care test whole-blood prothrombin time monitors (CoaguChek Mini and TAS PT-NC) by independent international sensitivity index calibration.
British journal of haematology 2003;122(6):944-9.
2003: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Caroline Shiach; Jørgen Jespersen
Reliability of international normalised ratios from two point of care test systems: comparison with conventional methods.
BMJ (Clinical research ed.) 2003;327(7405):30.
2003: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Caroline Shiach; Jørgen Jespersen
European Concerted Action on Anticoagulation (ECAA): an assessment of a method for ISI calibration of two whole blood point-of-care PT monitor systems based on lyophilized plasmas using whole blood equivalent PT.
Journal of thrombosis and haemostasis : JTH 2003;1(4):766-72.
2003: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Jørgen Jespersen; Caroline Shiach
European concerted action on anticoagulation. Minimum numbers of lyophilized plasma samples for ISI calibration of CoaguChek and TAS point-of-care whole blood prothrombin time monitors.
American journal of clinical pathology 2003;119(2):232-40.
2003: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Caroline Shiach; Jørgen Jespersen
European Concerted Action on Anticoagulation (ECAA). An assessment of lyophilised plasmas for ISI calibration of CoaguChek and TAS whole blood prothrombin time monitors.
Journal of clinical pathology 2003;56(2):114-9.
2002: Leon Poller; Michelle Keown; Nikhil Chauhan; Caroline Shiach; A M H P van den Besselaar; Armando Tripodi; Jørgen Jespersen
European Concerted Action on Anticoagulation (ECAA): International Normalized Ratio variability of CoaguChek and TAS point-of-care testing whole blood prothrombin time monitors.
Thrombosis and haemostasis 2002;88(6):992-5.
2002: Caroline Shiach; Bonnie Campbell; Leon Poller; Michelle Keown; Nikhil Chauhan
Reliability of point-of-care prothrombin time testing in a community clinic: a randomized crossover comparison with hospital laboratory testing.
British journal of haematology 2002;119(2):370-5.
2002: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Caroline Shiach; Jørgen Jespersen
European Concerted Action on Anticoagulation. Evaluation of a method for International Sensitivity Index calibration of two point-of-care prothrombin time (PT) monitoring systems (CoaguChek Mini and TAS PT-NC) with fresh plasmas based on whole-blood equivalent PT.
Clinical chemistry 2002;48(10):1672-80.
2002: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Caroline Shiach; Jørgen Jespersen
European Concerted Action on Anticoagulation (ECAA). Minimum number of centres for reliable International Sensitivity Index calibration of CoaguChek and TAS point-of-care whole blood monitors.
Thrombosis research 2002;107(1-2):61-6.
2002: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Jørgen Jespersen; Caroline Shiach
Minimum numbers of fresh whole blood and plasma samples from patients and healthy subjects for ISI calibration of CoaguChek and RapidPointCoag monitors.
American journal of clinical pathology 2002;117(6):892-9.
2002: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Caroline Shiach; Jørgen Jespersen
European Concerted Action on Anticoagulation--comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors.
Thrombosis and haemostasis 2002;87(5):859-66.
2002: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Armando Tripodi; Jørgen Jespersen; Caroline Shiach; M H Horellou; D Dias; N Egberg; J A Iriarte; I Kontopoulou-Griva; B Otridge
European Concerted Action on Anticoagulation (ECAA): multicentre international sensitivity index calibration of two types of point-of-care prothrombin time monitor systems.
British journal of haematology 2002;116(4):844-50.
2002: Leon Poller; Michelle Keown; Nikhil Chauhan; A M H P van den Besselaar; Joyce Meeuwisse-Braun; Armando Tripodi; Mariagrazia Clerici; Jørgen Jespersen
European concerted action on anticoagulation. Use of plasma samples to derive international sensitivity index for whole-blood prothrombin time monitors.
Clinical chemistry 2002;48(2):255-60.
2001: Jack Ansell; Jack Hirsh; JE Dalen; Henry Bussey; D Anderson; Leon Poller; Alan Jacobson; D Deykin; D Matchar
Managing oral anticoagulant therapy.
Chest 2001;119(1 Suppl):22S-38S.
2001: Jack Hirsh; JE Dalen; D R Anderson; Leon Poller; Henry Bussey; Jack Ansell; D Deykin
Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range.
Chest 2001;119(1 Suppl):8S-21S.
1999: Leon Poller; Michelle Keown; S A Shepherd; Caroline Shiach; S Tabeart
The effects of freeze drying and freeze drying additives on the prothrombin time and the international sensitivity index.
Journal of clinical pathology 1999;52(10):744-8.
1999: Leon Poller; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
Correction for lack of coincidence of normal and abnormal calibration slopes in ISI determination.
Thrombosis and haemostasis 1999;81(6):935-9.
1999: Leon Poller; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
The effect of sample size on fresh plasma thromboplastin ISI determination.
British journal of haematology 1999;105(3):655-63.
1998: Leon Poller; Caroline Shiach; P K MacCallum; A M Johansen; Anna-Marie Bloch Münster; A Magalhães; Jørgen Jespersen
Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation.
Lancet 1998;352(9139):1505-9.
1998: Jack Hirsh; JE Dalen; D R Anderson; Leon Poller; Henry Bussey; Jack Ansell; D Deykin; John T Brandt
Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range.
Chest 1998;114(5 Suppl):445S-469S.
1998: Leon Poller; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
The European Concerted Action on Anticoagulation (ECAA): field studies of coagulometer effects on the ISI of ECAA thromboplastins.
Thrombosis and haemostasis 1998;80(4):615-23.
1998: RB Fairweather; Jack Ansell; A M H P van den Besselaar; John T Brandt; Henry Bussey; Leon Poller; DA Triplett; Richard H White
College of American Pathologists Conference XXXI on laboratory monitoring of anticoagulant therapy: laboratory monitoring of oral anticoagulant therapy.
Archives of pathology & laboratory medicine 1998;122(9):768-81.
1998: Leon Poller; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
A comparison of linear and orthogonal regression analysis for local INR determination in ECAA coagulometer studies. European Concerted Action on Anticoagulation.
British journal of haematology 1998;102(4):910-7.
1998: Leon Poller; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
A comparison of artificially-depleted, lyophilized coumarin and fresh coumarin plasmas in thromboplastin calibration. European Concerted Action on Anticoagulation.
British journal of haematology 1998;101(3):462-7.
1998: Leon Poller
Screening INR deviation of local prothrombin time systems.
Journal of clinical pathology 1998;51(5):356-9.
1998: Leon Poller; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
The importance of "like to like" ISI calibrations with freeze dried plasmas. European Concerted Action on Anticoagulation.
Journal of clinical pathology 1998;51(4):275-9.
1998: Leon Poller; TW Barrowcliffe; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
Minimum lyophilized plasma requirement for ISI calibration. European Concerted Action on Anticoagulation.
American journal of clinical pathology 1998;109(2):196-204.
1998: D Wright; Leon Poller; J M Thomson; A Sidebotham; C F Hirst; P Hirsch
A longitudinal study of the factor VII rise during pregnancy.
Thrombosis and haemostasis 1998;79(2):328-30.
1998: Leon Poller; TW Barrowcliffe; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
The European Concerted Action on Anticoagulation (ECAA) evaluation of a set of lyophilized normal plasmas to establish the normal prothrombin time for coagulometer systems.
Thrombosis and haemostasis 1998;79(1):122-8.
1997: Leon Poller; TW Barrowcliffe; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
A simplified statistical method for local INR using linear regression. European Concerted Action on Anticoagulation.
British journal of haematology 1997;98(3):640-7.
1997: A M H P van den Besselaar; CJ van Rijn; D A Taberner; L J Goodman; Leon Poller; K Clarke
Heat stability of two candidate international reference preparations for recombinant human tissue factor.
Thrombosis and haemostasis 1997;78(2):852-4.
1997: D Wright; Leon Poller; J M Thomson; G E Burrows; C F Hirst; A Sidebotham
The effect of hormone replacement therapy of the age-related rise of factor VIIc, and its activity state.
Thrombosis research 1997;85(6):455-64.
1996: Leon Poller; TW Barrowcliffe; A M H P van den Besselaar; Jørgen Jespersen; Armando Tripodi; D Houghton
European Concerted Action on Anticoagulation (ECAA)-the multicentre calibration of rabbit and human ECAA reference thromboplastins. Steering Committee.
Thrombosis and haemostasis 1996;76(6):977-82.
1995: Leon Poller; D A Triplett; J Hirsh; J Carroll; K Clarke
A comparison of lyophilized artificially depleted plasmas and lyophilized plasmas from patients receiving warfarin in correcting for coagulometer effects on international normalized ratios.
American journal of clinical pathology 1995;103(3):366-71.
1995: Leon Poller; D A Triplett; J Hirsh; J Carroll; K Clarke
The value of plasma calibrants in correcting coagulometer effects on international normalized ratios. An international multicenter study.
American journal of clinical pathology 1995;103(3):358-65.
1994: Leon Poller; M Samama
Laboratory monitoring of oral anticoagulant therapy.
Clinics in laboratory medicine 1994;14(4):813-23.
1994: Leon Poller; D Houghton; J Carroll
The reliability of the mean normal prothrombin time of fresh plasmas and of the normal value from a lyophilized 'normal' plasma in prothrombin ratio determination.
British journal of haematology 1994;88(4):866-73.
1994: Leon Poller; J Pulford; K J Stevenson; P Cooper; G Gamble; J M Thomson
Long-term stability studies on the WHO IRP for thromboplastin (human plain BCT/253).
Thrombosis and haemostasis 1994;72(5):682-4.
1994: Leon Poller; J M Thomson; D A Taberner; D K Clarke
The correction of coagulometer effects on international normalized ratios: a multicentre evaluation.
British journal of haematology 1994;86(1):112-7.
1993: D Wright; Leon Poller; J M Thomson; E Gowland; G E Burrows
The inter-relationship of factor VII and its activity state with plasma lipids in healthy male adults.
British journal of haematology 1993;85(2):348-51.
1993: Leon Poller; D A Taberner; J M Thomson; J Morris; R S Mibashan; N K Shinton
Effect of the choice of WHO International Reference Preparation for thromboplastin on International Normalised Ratios.
Journal of clinical pathology 1993;46(1):64-6.
1992: C F Hirst; Leon Poller
The cause of turbidity in lyophilised plasmas and its effects on coagulation tests.
Journal of clinical pathology 1992;45(8):701-3.
1992: C F Hirst; J Hewitt; Leon Poller
Trace levels of factor VIII in substrate plasma.
British journal of haematology 1992;81(2):305-6.
1992: Leon Poller
Therapeutic ranges for oral anticoagulation in different thromboembolic disorders.
Annals of hematology 1992;64(2):52-9.
1992: K Clarke; D A Taberner; J M Thomson; J A Morris; Leon Poller
Assessment of value of calibrated lyophilised plasmas to determine International Sensitivity Index for coagulometers.
Journal of clinical pathology 1992;45(1):58-60.
1990: P K MacCallum; J M Thomson; Leon Poller
Effects of fixed minidose warfarin on coagulation and fibrinolysis following major gynaecological surgery.
Thrombosis and haemostasis 1990;64(4):511-5.
1990: J M Thomson; D A Taberner; Leon Poller
Automation and prothrombin time: a United Kingdom field study of two widely used coagulometers.
Journal of clinical pathology 1990;43(8):679-84.
1990: Leon Poller; P K MacCallum; J M Thomson; W Kerns
Reduction of factor VII coagulant activity (VIIC), a risk factor for ischaemic heart disease, by fixed dose warfarin: a double blind crossover study.
British heart journal 1990;63(4):231-3.
1990: D A Taberner; Leon Poller; J M Thomson
Quality control of the prothrombin time and international normalized ratios. National and international schemes.
La Ricerca in clinica e in laboratorio 1990;20(1):59-69.
1989: Leon Poller; J M Thomson; D A Taberner
Use of the activated partial thromboplastin time for monitoring heparin therapy: problems and possible solutions.
La Ricerca in clinica e in laboratorio 1989;19(4):363-70.
1989: D A Taberner; Leon Poller; J M Thomson; G Lemon; F J Weighill
Randomized study of adjusted versus fixed low dose heparin prophylaxis of deep vein thrombosis in hip surgery.
The British journal of surgery 1989;76(9):933-5.
1989: Leon Poller; J Hirsh
Special report: a simple system for the derivation of International Normalized Ratios for the reporting of prothrombin time results with North American thromboplastin reagents.
American journal of clinical pathology 1989;92(1):124-6.
1989: Leon Poller; J M Thomson; D A Taberner
Effect of automation on prothrombin time test in NEQAS surveys.
Journal of clinical pathology 1989;42(1):97-100.
1989: D A Taberner; Leon Poller; J M Thomson; K V Darby
Effect of international sensitivity index (ISI) of thromboplastins on precision of international normalised ratios (INR)
Journal of clinical pathology 1989;42(1):92-6.
1988: Leon Poller
A simple nomogram for the derivation of international normalised ratios for the standardisation of prothrombin times.
Thrombosis and haemostasis 1988;60(1):18-20.
1988: Leon Poller; D A Taberner; J M Thomson; K V Darby
Survey of prothrombin time in National External Quality Assessment Scheme exercises (1980-87).
Journal of clinical pathology 1988;41(4):361-4.
1988: A McKernan; J M Thomson; Leon Poller
The reliability of international normalized ratios during short-term oral anticoagulant treatment.
Clinical and laboratory haematology 1988;10(1):63-71.
1987: Leon Poller; A McKernan; J M Thomson; M Elstein; P J Hirsch; J B Jones
Fixed minidose warfarin: a new approach to prophylaxis against venous thrombosis after major surgery.
British medical journal (Clinical research ed.) 1987;295(6609):1309-12.
1987: J M Thomson; D A Taberner; Leon Poller
Rabbit (to replace human) brain material in anticoagulant control.
Lancet 1987;1(8532):559.
1987: Leon Poller
INR--calibration of the therapeutic range.
Advances in experimental medicine and biology 1987;214():95-112.
1987: K P Schofield; J M Thomson; Leon Poller
Protein C response to induction and withdrawal of oral anticoagulant treatment.
Clinical and laboratory haematology 1987;9(3):255-62.
1986: J M Thomson; K V Darby; Leon Poller
Calibration of BCT/441, the ICSH reference preparation for thromboplastin.
Thrombosis and haemostasis 1986;55(3):379-82.
1986: K J Stevenson; A C Easton; A Curry; J M Thomson; Leon Poller
The reliability of activated partial thromboplastin time methods and the relationship to lipid composition and ultrastructure.
Thrombosis and haemostasis 1986;55(2):250-8.
1983: K J Stevenson; A C Easton; J M Thomson; Leon Poller
Lipid class composition and heparin sensitivity in the activated partial thromboplastin time.
Thrombosis and haemostasis 1983;50(2):601-3.