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David Pompliano

Research Profile

Living Beings

Escherichia coli

Chemicals & Drugs

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Drug Design

Procedures

Disorders

Bacterial Infections

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Publications

TOP 3
John Kulp; John L Kulp; David L Pompliano; Frank Guarnieri
Diverse fragment clustering and water exclusion identify protein hot spots.
Iñigo Angulo-Barturen; María Belén Jiménez-Díaz; Teresa Mulet; Joaquín Rullas; Esperanza Herreros; Santiago Ferrer; Elena Jiménez; arvin mendoza; Javier Regadera; Philip J Rosenthal; Ian Bathurst; David L Pompliano; Federico Gómez de las Heras; Domingo Gargallo-Viola
A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes.
John S Bradley; Robert Guidos; Steve Baragona; John G Bartlett; Ethan Rubinstein; George G Zhanel; Michael D Tino; David L Pompliano; Frank Tally; Praveen Tipirneni; Glenn S Tillotson; John H Powers; Glenn S Tillotson
Anti-infective research and development--problems, challenges, and solutions.

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All Publications

2011: John Kulp; John L Kulp; David L Pompliano; Frank Guarnieri
Diverse fragment clustering and water exclusion identify protein hot spots.
Journal of the American Chemical Society 2011;133(28):10740-3.
2008: Iñigo Angulo-Barturen; María Belén Jiménez-Díaz; Teresa Mulet; Joaquín Rullas; Esperanza Herreros; Santiago Ferrer; Elena Jiménez; arvin mendoza; Javier Regadera; Philip J Rosenthal; Ian Bathurst; David L Pompliano; Federico Gómez de las Heras; Domingo Gargallo-Viola
A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes.
PloS one 2008;3(5):e2252.
2007: John S Bradley; Robert Guidos; Steve Baragona; John G Bartlett; Ethan Rubinstein; George G Zhanel; Michael D Tino; David L Pompliano; Frank Tally; Praveen Tipirneni; Glenn S Tillotson; John H Powers; Glenn S Tillotson
Anti-infective research and development--problems, challenges, and solutions.
The Lancet infectious diseases 2007;7(1):68-78.
2007: David J Payne; Michael N Gwynn; David J Holmes; David L Pompliano
Drugs for bad bugs: confronting the challenges of antibacterial discovery.
Nature reviews. Drug discovery 2007;6(1):29-40.
2006: Robert Copeland; David L Pompliano; Thomas D Meek
Drug-target residence time and its implications for lead optimization.
Nature reviews. Drug discovery 2006;5(9):730-9.
2003: Ekaterina V Bobkova; Yong Ping Yan; Douglas Jordan; Michael Kurilla; David L Pompliano
Catalytic properties of mutant 23 S ribosomes resistant to oxazolidinones.
The Journal of biological chemistry 2003;278(11):9802-7.
2002: Maria D F S Barbosa; Siqi Lin; Jay A Markwalder; Jonathan A Mills; Joseph A DeVito; Christopher A Teleha; Vasudha Garlapati; Charles Liu; Andy Thompson; George L Trainor; Michael Kurilla; David L Pompliano
Regulated expression of the Escherichia coli lepB gene as a tool for cellular testing of antimicrobial compounds that inhibit signal peptidase I in vitro.
Antimicrobial agents and chemotherapy 2002;46(11):3549-54.
2002: Maria D F S Barbosa; Harold O Ross; Milton C Hillman; Raymond P Meade; Michael Kurilla; David L Pompliano
A multitarget assay for inhibitors of membrane-associated steps of peptidoglycan biosynthesis.
Analytical biochemistry 2002;306(1):17-22.
2002: Yi Zhang; Fude Yang; Yeh-Chih Kao; Michael Kurilla; David L Pompliano; ira dicker
Homogenous assays for Escherichia coli DnaB-stimulated DnaG primase and DnaB helicase and their use in screening for chemical inhibitors.
Analytical biochemistry 2002;304(2):174-9.
2002: Joseph A DeVito; Jonathan A Mills; Veronica G Liu; Anjana Agarwal; Christine F Sizemore; Zhongjie Yao; Daniel M Stoughton; Maria Grazia Cappiello; Maria D F S Barbosa; Lorie A Foster; David L Pompliano
An array of target-specific screening strains for antibacterial discovery.
Nature biotechnology 2002;20(5):478-83.
2002: Fude Yang; ira dicker; Michael Kurilla; David L Pompliano
PolC-type polymerase III of Streptococcus pyogenes and its use in screening for chemical inhibitors.
Analytical biochemistry 2002;304(1):110-6.
2002: Maria D F S Barbosa; Gaoyun Yang; Jie Fang; Michael Kurilla; David L Pompliano
Development of a whole-cell assay for peptidoglycan biosynthesis inhibitors.
Antimicrobial agents and chemotherapy 2002;46(4):943-6.
2002: Cynthia R Pennise; Nafsika H Georgopapadakou; R Dale Collins; Nilsa R Graciani; David L Pompliano
A continuous fluorometric assay of myristoyl-coenzyme A:protein N-myristoyltransferase.
Analytical biochemistry 2002;300(2):275-7.
2001: U Patel; Yong Ping Yan; F W Hobbs; J Kaczmarczyk; AM Slee; David L Pompliano; Michael Kurilla; Ekaterina V Bobkova
Oxazolidinones mechanism of action: inhibition of the first peptide bond formation.
The Journal of biological chemistry 2001;276(40):37199-205.