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Bruce Ponder

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Daechun Kang; Masaharu Kogure; Yoshihiko Maehara; Koichi Matsuda; Yusuke Nakamura; David E Neal; Bruce A J Ponder; Gouji Toyokawa; Tatsuhiko Tsunoda; Yuka Yamane; Hyun-Soo Cho; Helen I Field; Shinya Hayami; Yukiko Iwai; Ryuji Hamamoto
The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Hyun-Soo Cho; Yataro Daigo; Helen I Field; Shinya Hayami; Noriko Ikawa; John D Kelly; Yoshihiko Maehara; Kazuhiro Maejima; Ken Masuda; Yusuke Nakamura; David E Neal; Bruce A J Ponder; Gouji Toyokawa; Tatsuhiko Tsunoda; Yuka Yamane; Ryuji Hamamoto
The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
Masashi Takawa; Gouji Toyokawa; Tatsuhiko Tsunoda; Koji Ueda; Yuka Yamane; Takayuki Akasu; Yutaka Atomi; Hyun-Soo Cho; Naoshi Dohmae; Helen I Field; Shinya Hayami; Yukiko Iwai; Takaaki Kobayashi; Masaharu Kogure; Kazuhiro Maejima; Akiko Masuda; Yusuke Nakamura; Shin-ichi Ohnuma; Bruce A J Ponder; Masanori Sugiyama; Ryuji Hamamoto
Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.

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All Publications

2013: Daechun Kang; Masaharu Kogure; Yoshihiko Maehara; Koichi Matsuda; Yusuke Nakamura; David E Neal; Bruce A J Ponder; Gouji Toyokawa; Tatsuhiko Tsunoda; Yuka Yamane; Hyun-Soo Cho; Helen I Field; Shinya Hayami; Yukiko Iwai; Ryuji Hamamoto
The histone methyltransferase Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) is involved in human carcinogenesis.
Genes, chromosomes & cancer 2013;52(2):126-39.
2012: Hyun-Soo Cho; Yataro Daigo; Helen I Field; Shinya Hayami; Noriko Ikawa; John D Kelly; Yoshihiko Maehara; Kazuhiro Maejima; Ken Masuda; Yusuke Nakamura; David E Neal; Bruce A J Ponder; Gouji Toyokawa; Tatsuhiko Tsunoda; Yuka Yamane; Ryuji Hamamoto
The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene.
International journal of cancer. Journal international du cancer 2012;131(3):E179-89.
2012: Masashi Takawa; Gouji Toyokawa; Tatsuhiko Tsunoda; Koji Ueda; Yuka Yamane; Takayuki Akasu; Yutaka Atomi; Hyun-Soo Cho; Naoshi Dohmae; Helen I Field; Shinya Hayami; Yukiko Iwai; Takaaki Kobayashi; Masaharu Kogure; Kazuhiro Maejima; Akiko Masuda; Yusuke Nakamura; Shin-ichi Ohnuma; Bruce A J Ponder; Masanori Sugiyama; Ryuji Hamamoto
Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression.
Cancer research 2012;72(13):3217-27.
2012: Hyun-Soo Cho; Yataro Daigo; Helen I Field; Shinya Hayami; Noriko Ikawa; Akihiro Ito; Yoshihiko Maehara; Ken Masuda; Yusuke Nakamura; Shin-ichi Ohnuma; Bruce A J Ponder; Tadahiro Shimazu; Gouji Toyokawa; Eiju Tsuchiya; Minoru Yoshida; Ryuji Hamamoto
Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B.
Nature communications 2012;3():1072.
2011: Gouji Toyokawa; Tatsuhiko Tsunoda; Masanori Yoshimatsu; Hyun-Soo Cho; Helen I Field; Shinya Hayami; Yukiko Iwai; John D Kelly; Yoshihiko Maehara; Kazuhiro Maejima; Yusuke Nakamura; David E Neal; Bruce A J Ponder; Noriaki Shimizu; Masashi Takawa; Hirotoshi Tanaka; Ryuji Hamamoto
The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Cancer prevention research (Philadelphia, Pa.) 2011;4(12):2051-61.
2011: Kerstin B Meyer; Martin O'Reilly; Patricia Porter-Gill; Radhika Prathalingam; Ludmila Prokunina-Olsson; Stefan Ambs; Jason Carroll; Maya Ghoussaini; Ana-Teresa Maia; Bruce A J Ponder
A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression.
PLoS genetics 2011;7(7):e1002165.
2011: Masashi Takawa; Gouji Toyokawa; Eiju Tsuchiya; Yuka Yamane; Takayuki Akasu; Yutaka Atomi; Hyun-Soo Cho; Yataro Daigo; Helen I Field; Yukiko Iwai; Takaaki Kobayashi; Masaki Kunizaki; Kazuhiro Maejima; Ken Masuda; Yusuke Nakamura; Bruce A J Ponder; Masanori Sugiyama; Katsunori Takagi; Ryuji Hamamoto
Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
Cancer science 2011;102(7):1298-305.
2011: Hyun-Soo Cho; Takehiro Suzuki; Naoshi Dohmae; Shinya Hayami; Motoko Unoki; Masanori Yoshimatsu; Gouji Toyokawa; Masashi Takawa; Taiping Chen; Julia K Kurash; Helen I Field; Bruce A J Ponder; Yusuke Nakamura; Ryuji Hamamoto
Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells.
Cancer research 2011;71(3):655-60.
2011: Masanori Yoshimatsu; Gouji Toyokawa; Shinya Hayami; Motoko Unoki; Tatsuhiko Tsunoda; Helen I Field; John D Kelly; David E Neal; Yoshihiko Maehara; Bruce A J Ponder; Yusuke Nakamura; Ryuji Hamamoto
Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
International journal of cancer. Journal international du cancer 2011;128(3):562-73.
2011: Shinya Hayami; John D Kelly; Hyun-Soo Cho; Masanori Yoshimatsu; Motoko Unoki; Tatsuhiko Tsunoda; Helen I Field; David E Neal; Hiroki Yamaue; Bruce A J Ponder; Yusuke Nakamura; Ryuji Hamamoto
Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers.
International journal of cancer. Journal international du cancer 2011;128(3):574-86.
2010: Karen A Pooley; Jonathan Tyrer; Mitul Shah; Kristy E Driver; Jean Leyland; Judith Brown; Tina Audley; Lesley McGuffog; Bruce A J Ponder; Paul D P Pharoah; Douglas F Easton; Alison M Dunning
No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(7):1862-5.
2010: Karen A Pooley; Manjinder S Sandhu; Jonathan Tyrer; Mitul Shah; Kristy E Driver; Robert N Luben; Sheila A Bingham; Bruce A J Ponder; Paul D P Pharoah; Kay-Tee Khaw; Douglas F Easton; Alison M Dunning
Telomere length in prospective and retrospective cancer case-control studies.
Cancer research 2010;70(8):3170-6.
2009: Nasim Mavaddat; Alison M Dunning; Bruce A J Ponder; Douglas F Easton; Paul D Pharoah
Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(1):255-9.
2008: Karen A Pooley; Caroline Baynes; Kristy E Driver; Jonathan Tyrer; Elizabeth M Azzato; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(12):3482-9.
2008: Honglin Song; Thibaud Koessler; Shahana Ahmed; Susan J Ramus; Susanne Krüger Kjaer; Richard A DiCioccio; Eva Wozniak; Estrid Hogdall; Alice S Whittemore; Valerie McGuire; Bruce A J Ponder; Clare Turnbull; Sarah Hines; Nazneen Rahman; Rosalind A Eeles; Douglas F Easton; Simon A Gayther; Alison M Dunning; Paul D P Pharoah
Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.
Cancer research 2008;68(21):8837-42.
2008: Andrea Mann; Estrid Hogdall; Susan J Ramus; Richard A DiCioccio; Claus Hogdall; Lydia Quaye; Valerie McGuire; Alice S Whittemore; Mitul Shah; David Greenberg; Douglas F Easton; Bruce A J Ponder; Susanne Krüger Kjaer; Simon A Gayther; Deborah J Thompson; Paul D P Pharoah; Honglin Song
Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.
European journal of cancer (Oxford, England : 1990) 2008;44(15):2259-65.
2008: Lydia Quaye; Simon A Gayther; Susan J Ramus; Richard A Di Cioccio; Valerie McGuire; Estrid Hogdall; Claus Hogdall; Jan Blaakr; Douglas F Easton; Bruce A J Ponder; Ian Jacobs; Susanne Kruger Kjaer; Alice S Whittemore; Celeste L Pearce; Paul D P Pharoah; Honglin Song
The effects of common genetic variants in oncogenes on ovarian cancer survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5833-9.
2008: Gillian C Barnett; Mitul Shah; Karen Redman; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah
Risk factors for the incidence of breast cancer: do they affect survival from the disease?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(20):3310-6.
2008: Paul D P Pharoah; Antonis C Antoniou; Douglas F Easton; Bruce A J Ponder
Polygenes, risk prediction, and targeted prevention of breast cancer.
The New England journal of medicine 2008;358(26):2796-803.
2008: Kerstin B Meyer; Ana-Teresa Maia; Martin O'Reilly; Andrew E Teschendorff; Suet-Feung Chin; Carlos Caldas; Bruce A J Ponder
Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer.
PLoS biology 2008;6(5):e108.
2008: Kristy E Driver; Honglin Song; Fabienne LESUEUR; Shahana Ahmed; Nuno Barbosa-Morais; Jonathan Tyrer; Bruce A J Ponder; Douglas F Easton; Paul D P Pharoah; Alison M Dunning
Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.
Carcinogenesis 2008;29(2):333-41.
2008: Frances Mulvany; Bruce A J Ponder
Breast Cancer Research--the first ten years.
Breast cancer research : BCR 2008;10(2):103.
2007: Susan J Ramus; Patricia A Harrington; Carole Pye; Richard A DiCioccio; Mark J Cox; Kim Garlinghouse-Jones; Ingrid Oakley-Girvan; Ian J Jacobs; Richard M Hardy; Alice S Whittemore; Bruce A J Ponder; M Steven Piver; Paul D P Pharoah; Simon A Gayther
Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer.
Human mutation 2007;28(12):1207-15.
2007: Sergio Ruiz-Llorente; Cristina Montero-Conde; Roger L Milne; Christian M Moya; Arancha Cebrián; Rocío Letón; Alberto Cascón; Fátima Mercadillo; Iñigo Landa; Salud Borrego; Guiomar Pérez de Nanclares; Cristina Alvarez-Escolá; José Angel Díaz-Pérez; Angel Carracedo; Miguel Urioste; Anna González-Neira; Javier Benítez; Pilar Santisteban; Joaquín Dopazo; Bruce A J Ponder; Mercedes Robledo
Association study of 69 genes in the ret pathway identifies low-penetrance loci in sporadic medullary thyroid carcinoma.
Cancer research 2007;67(19):9561-7.
2007: Miriam Udler; Ana-Teresa Maia; Arancha Cebrian; Clement Brown; David Greenberg; Mitul Shah; Carlos Caldas; Alison M Dunning; Douglas Easton; Bruce A J Ponder; Paul Pharoah
Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(21):3015-23.
2007: Susan J Ramus; Patricia A Harrington; Carole Pye; Susan Peock; Margaret R Cook; Mark J Cox; Ian J Jacobs; Richard A DiCioccio; Alice S Whittemore; M Steven Piver; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah; Simon A Gayther
Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis. Mutation in brief #964. Online.
Human mutation 2007;28(5):525-6.
2007: David J Samuelson; Stephanie E Hesselson; Beth A Aperavich; Yunhong Zan; Jill D Haag; Amy Trentham-Dietz; John M Hampton; Bob Mau; Kai-Shun Chen; Caroline Baynes; Kay-Tee Khaw; Robert Luben; Barbara Perkins; Mitul Shah; Paul D P Pharoah; Alison M Dunning; Douglas F Easton; Bruce A J Ponder; Michael N Gould
Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6299-304.
2007: Paul D P Pharoah; Jonathan Tyrer; Alison M Dunning; Douglas F Easton; Bruce A J Ponder
Association between common variation in 120 candidate genes and breast cancer risk.
PLoS genetics 2007;3(3):e42.
2007: Caroline Baynes; Catherine S Healey; Karen A Pooley; Serena Scollen; Robert N Luben; Deborah J Thompson; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.
Breast cancer research : BCR 2007;9(2):R27.
2007: Honglin Song; Susan J Ramus; Susanne Krüger Kjaer; Estrid Hogdall; Richard A DiCioccio; Alice S Whittemore; Valerie McGuire; Claus Hogdall; Ian J Jacobs; Douglas F Easton; Bruce A J Ponder; Alison M Dunning; Simon A Gayther; Paul D P Pharoah
Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer.
PloS one 2007;2(3):e268.
2006: Patrick R Benusiglio; Paul D P Pharoah; Paula L Smith; Fabienne LESUEUR; Donald M Conroy; Robert N Luben; G Dew; Clare Jordan; Alison M Dunning; Douglas F Easton; Bruce A J Ponder
HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer.
British journal of cancer 2006;95(12):1689-95.
2006: Mark D Sternlicht; Alison M Dunning; Dan H Moore; Paul D P Pharoah; David Ginzinger; Koei Chin; Joe Gray; Frederic M Waldman; Bruce A J Ponder; Zena Werb
Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(11):2107-14.
2006: Honglin Song; Susan J Ramus; Lydia Quaye; Richard A DiCioccio; Jonathan Tyrer; Emma Lomas; Danielle Shadforth; Estrid Hogdall; Claus Hogdall; Valerie McGuire; Alice S Whittemore; Douglas F Easton; Bruce A J Ponder; Susanne Krüger Kjaer; Paul D P Pharoah; Simon A Gayther
Common variants in mismatch repair genes and risk of invasive ovarian cancer.
Carcinogenesis 2006;27(11):2235-42.
2006: Honglin Song; Susan J Ramus; Danielle Shadforth; Lydia Quaye; Susanne Krüger Kjaer; Richard A DiCioccio; Alison M Dunning; Estrid Hogdall; Claus Hogdall; Alice S Whittemore; Valerie McGuire; Fabienne LESUEUR; Douglas F Easton; Ian J Jacobs; Bruce A J Ponder; Simon A Gayther; Paul D P Pharoah
Common variants in RB1 gene and risk of invasive ovarian cancer.
Cancer research 2006;66(20):10220-6.
2006: Aaron N Cranston; Cristiana Carniti; Kim Oakhill; Elzbieta Radzio-Andzelm; Eric A Stone; Andy McCallion; Shirley Hodgson; Sue Clarke; Piera Mondellini; Jean Leyland; Marco A Pierotti; Joanne Whittaker; Susan S Taylor; Italia Bongarzone; Bruce A J Ponder
RET is constitutively activated by novel tandem mutations that alter the active site resulting in multiple endocrine neoplasia type 2B.
Cancer research 2006;66(20):10179-87.
2006: Mohamed K El-Tanani; Frederick Charles Campbell; Paul Crowe; Pauline Erwin; D Paul Harkin; Paul Pharoah; Bruce A J Ponder; Philip S Rudland
BRCA1 suppresses osteopontin-mediated breast cancer.
The Journal of biological chemistry 2006;281(36):26587-601.
2006: M Z Oestergaard; Jonathan Tyrer; Arancha Cebrian; Mitul Shah; Alison M Dunning; Bruce A J Ponder; Douglas F Easton; Paul D P Pharoah
Interactions between genes involved in the antioxidant defence system and breast cancer risk.
British journal of cancer 2006;95(4):525-31.
2006: Ruth Warren; Jane Skinner; Evis Sala; Erika Denton; Mitch Dowsett; Elizabeth Folkerd; Catherine S Healey; Alison M Dunning; Deborah Doody; Bruce A J Ponder; Robert N Luben; Nicholas E Day; Douglas Easton
Associations among mammographic density, circulating sex hormones, and polymorphisms in sex hormone metabolism genes in postmenopausal women.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(8):1502-8.
2006: Arancha Cebrian; Paul D P Pharoah; Shahana Ahmed; Santiago Ropero; Mario F Fraga; Paula L Smith; Donald M Conroy; Robert Luben; Barbara Perkins; Douglas F Easton; Alison M Dunning; Manel Esteller; Bruce A J Ponder
Genetic variants in epigenetic genes and breast cancer risk.
Carcinogenesis 2006;27(8):1661-9.
2006: Aaron N Cranston; Cristiana Carniti; Sam Martin; Piera Mondellini; Yvette Hooks; Jean Leyland; Shirley Hodgson; Sue Clarke; Marco A Pierotti; Bruce A J Ponder; Italia Bongarzone
A novel activating mutation in the RET tyrosine kinase domain mediates neoplastic transformation.
Molecular endocrinology (Baltimore, Md.) 2006;20(7):1633-43.
2006: Fabienne LESUEUR; Honglin Song; Shahana Ahmed; Craig Luccarini; Clare Jordan; Robert Luben; Douglas F Easton; Alison M Dunning; Paul D P Pharoah; Bruce A J Ponder
Single-nucleotide polymorphisms in the RB1 gene and association with breast cancer in the British population.
British journal of cancer 2006;94(12):1921-6.
2006: Karen A Pooley; Catherine S Healey; Paula L Smith; Paul D P Pharoah; Deborah Thompson; Louise Tee; Judith West; Clare Jordan; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
Association of the progesterone receptor gene with breast cancer risk: a single-nucleotide polymorphism tagging approach.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(4):675-82.
2006: Cristiana Carniti; Sara Belluco; Elena Riccardi; Aaron N Cranston; Piera Mondellini; Bruce A J Ponder; Eugenio Scanziani; Marco A Pierotti; Italia Bongarzone
The Ret(C620R) mutation affects renal and enteric development in a mouse model of Hirschsprung's disease.
The American journal of pathology 2006;168(4):1262-75.
2006: Arancha Cebrian; Paul D P Pharoah; Shahana Ahmed; Paula L Smith; Craig Luccarini; Robert Luben; Karen Redman; Hannah Munday; Douglas F Easton; Alison M Dunning; Bruce A J Ponder
Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer.
Cancer research 2006;66(2):1225-33.
2006: Fabienne LESUEUR; Arancha Cebrian; Mercedes Robledo; Patricia Niccoli-Sire; Karl-Axel Svensson; Stephane Pinson; Jean Leyland; Joanne Whittaker; Paul D P Pharoah; Bruce A J Ponder
Polymorphisms in RET and its coreceptors and ligands as genetic modifiers of multiple endocrine neoplasia type 2A.
Cancer research 2006;66(2):1177-80.
2006: Ali S Alzahrani; Manjinder S Sandhu; Robert N Luben; Deborah Thompson; Caroline Baynes; Karen A Pooley; Craig Luccarini; Hannah Munday; Barbara Perkins; Paula Smith; Paul D P Pharoah; Nicholas J Wareham; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer.
Human molecular genetics 2006;15(1):1-10.
2005: Patrick R Benusiglio; Craig Luccarini; Oluseun Ajai; Bruce A J Ponder; Paul D P Pharoah
Reply: a bias in genotyping of the ERBB2 (HER2) Ile655Val variant.
Carcinogenesis 2005;26(12):2213.
2005: Annika Auranen; Honglin Song; Christy Waterfall; Richard A DiCioccio; Bettina Kuschel; Susanne Krüger Kjaer; Estrid Hogdall; Claus Hogdall; John Stratton; Alice S Whittemore; Douglas F Easton; Bruce A J Ponder; Karen L Novik; Alison M Dunning; Simon A Gayther; Paul D P Pharoah
Polymorphisms in DNA repair genes and epithelial ovarian cancer risk.
International journal of cancer. Journal international du cancer 2005;117(4):611-8.
2005: Miriam Böckmann; Gero Hilken; Anke Schmidt; Aaron N Cranston; Andrea Tannapfel; Matthias Drosten; Andrea Frilling; Bruce A J Ponder; Brigitte M Pützer
Novel SRESPHP peptide mediates specific binding to primary medullary thyroid carcinoma after systemic injection.
Human gene therapy 2005;16(11):1267-75.
2005: Arancha Cebrian; Fabienne LESUEUR; Sam Martin; Jean Leyland; Shahana Ahmed; Craig Luccarini; Paula L Smith; Robert Luben; Joanne Whittaker; Paul D P Pharoah; Alison M Dunning; Bruce A J Ponder
Polymorphisms in the initiators of RET (rearranged during transfection) signaling pathway and susceptibility to sporadic medullary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 2005;90(11):6268-74.
2005: Fabienne LESUEUR; Paul D P Pharoah; Stewart Laing; Shahana Ahmed; Clare Jordan; Paula L Smith; Robert Luben; Nicholas J Wareham; Douglas F Easton; Alison M Dunning; Bruce A J Ponder
Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer.
Human molecular genetics 2005;14(16):2349-56.
2005: Bettina Kuschel; Georgia Chenevix-Trench; Amanda B Spurdle; Xiaoqing Chen; John L Hopper; Graham G Giles; Margret McCredie; Jenny Chang-Claude; Catherine S Gregory; Nicholas E Day; Douglas F Easton; Bruce A J Ponder; Alison M Dunning; Paul D P Pharoah
Common polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not associated with breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(7):1828-31.
2005: Paul D P Pharoah; Alison M Dunning; Bruce A J Ponder; Douglas F Easton
The reliable identification of disease-gene associations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(6):1362.
2005: Fabienne LESUEUR; Arancha Cebrian; Aaron N Cranston; Jean Leyland; T M Faid; M R Clements; Mercedes Robledo; Joanne Whittaker; Bruce A J Ponder
Germline homozygous mutations at codon 804 in the RET protooncogene in medullary thyroid carcinoma/multiple endocrine neoplasia type 2A patients.
The Journal of clinical endocrinology and metabolism 2005;90(6):3454-7.
2005: Alberto Cascon; Arancha Cebrian; Marina Pollan; Sergio Ruiz-Llorente; Cristina Montero-Conde; Rocio Leton; Ruth Gutierrez; Fabienne LESUEUR; Roger L Milne; Olga Gonzalez-Albarran; Tomas Lucas-Morante; Javier Benitez; Bruce A J Ponder; Mercedes Robledo
Succinate dehydrogenase D variants do not constitute a risk factor for developing C cell hyperplasia or sporadic medullary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 2005;90(4):2127-30.
2005: Sheng-ping Hu; Nicholas E Day; D R Li; R N Luben; Ke-Li Cai; T Ou-Yang; Biao Li; X Z Lu; Bruce A J Ponder
Further evidence for an HLA-related recessive mutation in nasopharyngeal carcinoma among the Chinese.
British journal of cancer 2005;92(5):967-70.
2005: Bruce A J Ponder; A Antoniou; Alison M Dunning; Douglas F Easton; Paul D P Pharoah
Polygenic inherited predisposition to breast cancer.
Cold Spring Harbor symposia on quantitative biology 2005;70():35-41.
2005: Patrick R Benusiglio; Fabienne LESUEUR; Craig Luccarini; Joan McIntosh; Robert N Luben; Paula Smith; Alison M Dunning; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah
Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs.
BMC cancer 2005;5():81.
2005: Patrick R Benusiglio; Fabienne LESUEUR; Craig Luccarini; Donald M Conroy; Mitul Shah; Douglas F Easton; Nicholas E Day; Alison M Dunning; Paul D P Pharoah; Bruce A J Ponder
Common ERBB2 polymorphisms and risk of breast cancer in a white British population: a case-control study.
Breast cancer research : BCR 2005;7(2):R204-9.
2004: Gordon MacPherson; Catherine S Healey; M Dawn Teare; Sabapathy P Balasubramanian; M W R Reed; Paul D P Pharoah; Bruce A J Ponder; Mark Meuth; Nitai P Bhattacharyya; Angela Cox
Association of a common variant of the CASP8 gene with reduced risk of breast cancer.
Journal of the National Cancer Institute 2004;96(24):1866-9.
2004: Alice S Whittemore; Raymond R Balise; Paul D P Pharoah; Richard A DiCioccio; Ingrid Oakley-Girvan; Susan J Ramus; M Daly; M B Usinowicz; Kim Garlinghouse-Jones; Bruce A J Ponder; Saundra S Buys; R Senie; Irene L Andrulis; E John; John L Hopper; M Steven Piver
Oral contraceptive use and ovarian cancer risk among carriers of BRCA1 or BRCA2 mutations.
British journal of cancer 2004;91(11):1911-5.
2004: Paul D P Pharoah; Alison M Dunning; Bruce A J Ponder; Douglas F Easton
Association studies for finding cancer-susceptibility genetic variants.
Nature reviews. Cancer 2004;4(11):850-60.
2004: Richard A DiCioccio; Honglin Song; Christy Waterfall; Makoto T Kimura; Hiroki Nagase; Valerie McGuire; Estrid Hogdall; Mitul N Shah; Robert N Luben; Douglas F Easton; Ian J Jacobs; Bruce A J Ponder; Alice S Whittemore; Simon A Gayther; Paul D P Pharoah; Susan Kruger-Kjaer
STK15 polymorphisms and association with risk of invasive ovarian cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2004;13(10):1589-94.
2004: Matthias Drosten; Gero Hilken; Miriam Böckmann; Florian Rödicker; Nikica Mise; Aaron N Cranston; Uta Dahmen; Bruce A J Ponder; Brigitte M Pützer
Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma.
Journal of the National Cancer Institute 2004;96(16):1231-9.
2004: Alison M Dunning; Mitch Dowsett; Catherine S Healey; Louise Tee; Robert N Luben; Elizabeth Folkerd; Karen L Novik; Livia Kelemen; Saeko Ogata; Paul D P Pharoah; Douglas F Easton; Nicholas E Day; Bruce A J Ponder
Polymorphisms associated with circulating sex hormone levels in postmenopausal women.
Journal of the National Cancer Institute 2004;96(12):936-45.
2004: Yataro Daigo; Ichiro Takayama; Bruce A J Ponder; Carlos Caldas; Sean M Ward; Kenton M Sanders; Masayuki A Fujino
Novel human, mouse and xenopus genes encoding a member of the RAS superfamily of low-molecular-weight GTP-binding proteins and its downregulation in W/WV mouse jejunum.
Journal of gastroenterology and hepatology 2004;19(2):211-7.
2004: Bruce A Werness; Susan J Ramus; Richard A DiCioccio; Alice S Whittemore; Kim Garlinghouse-Jones; Ingrid Oakley-Girvan; Yoshiaki Tsukada; Patricia Harrington; Simon A Gayther; Bruce A J Ponder; M Steven Piver
Histopathology, FIGO stage, and BRCA mutation status of ovarian cancers from the Gilda Radner Familial Ovarian Cancer Registry.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2004;23(1):29-34.
2003: Luke Hughes-Davies; David Huntsman; Margarida Ruas; François Fuks; Jacqueline Bye; Suet-Feung Chin; Jonathon Milner; Lindsay A Brown; Forrest Hsu; Blake Gilks; Torsten Nielsen; Michael Schulzer; Stephen Chia; Joseph Ragaz; Anthony Cahn; Lori Linger; Hilal Ozdag; Elena Cattaneo; Ekaterina S. Jordanova; Edward Schuuring; David S Yu; Ashok R Venkitaraman; Bruce A J Ponder; Aidan Doherty; Samuel A J R Aparicio; David Bentley; Charles Theillet; Chris P Ponting; Carlos Caldas; Tony Kouzarides
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.
Cell 2003;115(5):523-35.
2003: Aaron N Cranston; Bruce A J Ponder
Modulation of medullary thyroid carcinoma penetrance suggests the presence of modifier genes in a RET transgenic mouse model.
Cancer research 2003;63(16):4777-80.
2003: Bettina Kuschel; Annika Auranen; C S Gregory; Nicholas E Day; Douglas F Easton; Bruce A J Ponder; Alison M Dunning; Paul D P Pharoah
Common polymorphisms in checkpoint kinase 2 are not associated with breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(8):809-12.
2003: Amanda E. Toland; Paraskevi Briassouli; John P de Koning; Jian-Hua Mao; Jinwei Yuan; Florence Chan; Lucy MacCarthy-Morrogh; Bruce A J Ponder; Hiroki Nagase; John Burn; Sarah Ball; Maria Almeida; Spiros Linardopoulos; Allan Balmain
Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human.
Nature genetics 2003;34(4):403-12.
2003: Yataro Daigo; Ichiro Takayama; Bruce A J Ponder; Carlos Caldas; Sean M Ward; Kenton M Sanders; Masayuki A Fujino
Differential gene expression profile in the small intestines of mice lacking pacemaker interstitial cells of Cajal.
BMC gastroenterology 2003;3():17.
2003: Yataro Daigo; Ichiro Takayama; Bruce A J Ponder; Carlos Caldas; Sean M Ward; Kenton M Sanders; Masayuki A Fujino
Differential gene expression in the murine gastric fundus lacking interstitial cells of Cajal.
BMC gastroenterology 2003;3():14.
2003: Alison M Dunning; Peter D Ellis; Simon McBride; Heidi L Kirschenlohr; Catherine S Healey; Paul R Kemp; Robert N Luben; Jenny Chang-Claude; Arto Mannermaa; Vesa Kataja; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder; James C Metcalfe
A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.
Cancer research 2003;63(10):2610-5.
2003: Annika Auranen; Amanda B Spurdle; Xiaoqing Chen; Julian M Lipscombe; David M Purdie; John L Hopper; Adele Green; Catherine S Healey; Karen Redman; Alison M Dunning; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder; Georgia Chenevix-Trench; Karen L Novik
BRCA2 Arg372Hispolymorphism and epithelial ovarian cancer risk.
International journal of cancer. Journal international du cancer 2003;103(3):427-30.
2003: Susan J Ramus; Paul D P Pharoah; Patricia Harrington; Carole Pye; Bruce A Werness; Lynda Bobrow; Ayse Ayhan; Dagan Wells; Ami Fishman; Martin Gore; Richard A DiCioccio; M Steven Piver; Alice S Whittemore; Bruce A J Ponder; Simon A Gayther
BRCA1/2 mutation status influences somatic genetic progression in inherited and sporadic epithelial ovarian cancer cases.
Cancer research 2003;63(2):417-23.
2003: Andreas Weinhaeusel; Annemarie Behmel; Bruce A J Ponder; Oskar A Haas; Bruno Niederle; Alois Gessl; Heinrich Vierhapper; Roswitha Pfragner
Long-term follow up of a "sporadic" unilateral pheochromocytoma revealing multiple endocrine neoplasia MEN2A-2 in an elderly woman.
Endocrine pathology 2003;14(4):375-82.
2003: V Craig Jordan; Bruce A J Ponder
Introducing a new section to Breast Cancer Research: endocrinology and hormone therapy.
Breast cancer research : BCR 2003;5(6):281-3.
2003: Stephen M Edwards; Zsofia Kote-Jarai; Julia Meitz; Rifat A Hamoudi; Questa Hope; Peter Osin; Rachel Jackson; Christine Southgate; Rashmi Singh; Alison Falconer; David P Dearnaley; Audrey Ardern-Jones; Annette Murkin; Anna Dowe; Jo Kelly; Sue Williams; Richard Oram; Margaret Stevens; Dawn M Teare; Bruce A J Ponder; Simon A Gayther; Douglas F Easton; Rosalind A Eeles
Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.
American journal of human genetics 2003;72(1):1-12.
2002: H Ozdağ; SJ Batley; A Försti; N Gopalakrishna Iyer; Yataro Daigo; J Boutell; Mark J Arends; Bruce A J Ponder; Tony Kouzarides; Carlos Caldas
Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not in primary tumours.
British journal of cancer 2002;87(10):1162-5.
2002: Paul D P Pharoah; Bruce A J Ponder
The genetics of ovarian cancer.
Best practice & research. Clinical obstetrics & gynaecology 2002;16(4):449-68.
2002: Ellen L Goode; Alison M Dunning; Bettina Kuschel; Catherine S Healey; Nicholas E Day; Bruce A J Ponder; Douglas F Easton; Paul P D Pharoah
Effect of germ-line genetic variation on breast cancer survival in a population-based study.
Cancer research 2002;62(11):3052-7.
2002: Bettina Kuschel; Annika Auranen; Simon McBride; Karen L Novik; Antonis Antoniou; Julian M Lipscombe; Nicholas E Day; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah; Alison M Dunning
Variants in DNA double-strand break repair genes and breast cancer susceptibility.
Human molecular genetics 2002;11(12):1399-407.
2002: Paul D P Pharoah; Antonis Antoniou; Martin Bobrow; Ron L Zimmern; Douglas F Easton; Bruce A J Ponder
Polygenic susceptibility to breast cancer and implications for prevention.
Nature genetics 2002;31(1):33-6.
2002: Irina V Tereschenko; Victoria M Basham; Bruce A J Ponder; Paul D P Pharoah
BRCA1 and BRCA2 mutations in Russian familial breast cancer.
Human mutation 2002;19(2):184.
2002: Victoria M Basham; Julian M Lipscombe; Joanna M Ward; Simon A Gayther; Bruce A J Ponder; Douglas F Easton; Paul D P Pharoah
BRCA1 and BRCA2 mutations in a population-based study of male breast cancer.
Breast cancer research : BCR 2002;4(1):R2.
2001: Victoria M Basham; Paul D P Pharoah; Catherine S Healey; Robert N Luben; Nicholas E Day; Douglas F Easton; Bruce A J Ponder; Alison M Dunning
Polymorphisms in CYP1A1 and smoking: no association with breast cancer risk.
Carcinogenesis 2001;22(11):1797-800.
2001: L Reynolds; K Jones; Douglas J Winton; Aaron N Cranston; Carol Houghton; Louise Howard; Bruce A J Ponder; DP Smith
C-cell and thyroid epithelial tumours and altered follicular development in transgenic mice expressing the long isoform of MEN 2A RET.
Oncogene 2001;20(30):3986-94.
2001: Antonis C Antoniou; Paul D P Pharoah; GJ McMullan; Nicholas E Day; Bruce A J Ponder; Douglas Easton
Evidence for further breast cancer susceptibility genes in addition to BRCA1 and BRCA2 in a population-based study.
Genetic epidemiology 2001;21(1):1-18.
2001: Bruce A J Ponder
Cancer genetics.
Nature 2001;411(6835):336-41.
2001: Yataro Daigo; Suet-Feung Chin; Kylie L Gorringe; Lynda Bobrow; Bruce A J Ponder; Paul D P Pharoah; Carlos Caldas
Degenerate oligonucleotide primed-polymerase chain reaction-based array comparative genomic hybridization for extensive amplicon profiling of breast cancers : a new approach for the molecular analysis of paraffin-embedded cancer tissue.
The American journal of pathology 2001;158(5):1623-31.
2001: Bettina Kuschel; Simon A Gayther; Douglas F Easton; Bruce A J Ponder; Paul D P Pharoah
Apparent human BRCA1 knockout caused by mispriming during polymerase chain reaction: implications for genetic testing.
Genes, chromosomes & cancer 2001;31(1):96-8.
2001: Susan J Ramus; Ami Fishman; Paul D P Pharoah; S Yarkoni; M Altaras; Bruce A J Ponder
Ovarian cancer survival in Ashkenazi Jewish patients with BRCA1 and BRCA2 mutations.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2001;27(3):278-81.
2000: Alison M Dunning; Francine Durocher; Catherine S Healey; M Dawn Teare; Simon McBride; F Carlomagno; Chun-Fang Xu; Elisabeth Dawson; S Rhodes; S Ueda; E Lai; Robert N Luben; E J Van Rensburg; Arto Mannermaa; Vesa Kataja; G Rennart; Carl Bruder; Ian Purvis; Douglas Easton; Bruce A J Ponder
The extent of linkage disequilibrium in four populations with distinct demographic histories.
American journal of human genetics 2000;67(6):1544-54.
2000: Bruce A Werness; Susan J Ramus; Alice S Whittemore; Kim Garlinghouse-Jones; Ingrid Oakley-Girvan; Richard A DiCioccio; Yoshiaki Tsukada; Bruce A J Ponder; M Steven Piver
Histopathology of familial ovarian tumors in women from families with and without germline BRCA1 mutations.
Human pathology 2000;31(11):1420-4.
2000: Catherine S Healey; Alison M Dunning; M Dawn Teare; D Chase; L Parker; J Burn; Jenny Chang-Claude; Arto Mannermaa; Vesa Kataja; David Huntsman; Paul D P Pharoah; Robert N Luben; Douglas F Easton; Bruce A J Ponder
A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability.
Nature genetics 2000;26(3):362-4.
2000: Bruce A Werness; Susan J Ramus; Alice S Whittemore; Kim Garlinghouse-Jones; Ingrid Oakley-Girvan; Richard A DiCioccio; Yoshiaki Tsukada; Bruce A J Ponder; M Steven Piver
Primary ovarian dysgerminoma in a patient with a germline BRCA1 mutation.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2000;19(4):390-4.
2000: David Huen; M Elsdon; Bruce A J Ponder
The Drosophila Ret gene is transcribed in multiple alternatively spliced forms.
Molecular & general genetics : MGG 2000;264(3):335-40.
2000: Simon A Gayther; KA de Foy; Patricia Harrington; Paul Pharoah; WD Dunsmuir; Stephen M Edwards; CE Gillett; Audrey Ardern-Jones; David P Dearnaley; Douglas F Easton; D Ford; R J Shearer; RS Kirby; Anna Dowe; Jo Kelly; Michael R Stratton; Bruce A J Ponder; D Barnes; Rosalind A Eeles
The frequency of germ-line mutations in the breast cancer predisposition genes BRCA1 and BRCA2 in familial prostate cancer. The Cancer Research Campaign/British Prostate Group United Kingdom Familial Prostate Cancer Study Collaborators.
Cancer research 2000;60(16):4513-8.
2000: P A Russell; Paul D P Pharoah; KA de Foy; Susan J Ramus; I Symmonds; A Wilson; I Scott; Bruce A J Ponder; Simon A Gayther
Frequent loss of BRCA1 mRNA and protein expression in sporadic ovarian cancers.
International journal of cancer. Journal international du cancer 2000;87(3):317-21.
2000: Bruce A Werness; P Parvatiyar; Susan J Ramus; Alice S Whittemore; Kim Garlinghouse-Jones; Ingrid Oakley-Girvan; Richard A DiCioccio; Jonathan S Wiest; Yoshiaki Tsukada; Bruce A J Ponder; M Steven Piver
Ovarian carcinoma in situ with germline BRCA1 mutation and loss of heterozygosity at BRCA1 and TP53.
Journal of the National Cancer Institute 2000;92(13):1088-91.
2000: S Sutcliffe; Paul D P Pharoah; Douglas F Easton; Bruce A J Ponder
Ovarian and breast cancer risks to women in families with two or more cases of ovarian cancer.
International journal of cancer. Journal international du cancer 2000;87(1):110-7.
2000: C H Knowles; S A Gayther; M Scott; Susan J Ramus; P Anand; Norman S Williams; Bruce A J Ponder
Idiopathic slow-transit constipation is not associated with mutations of the RET proto-oncogene or GDNF.
Diseases of the colon and rectum 2000;43(6):851-7.
2000: Paul D P Pharoah; Julian M Lipscombe; Karen Redman; Nicholas E Day; Douglas F Easton; Bruce A J Ponder
Familial predisposition to breast cancer in a British population: implications for prevention.
European journal of cancer (Oxford, England : 1990) 2000;36(6):773-9.
2000: F Carlomagno; Neil G Burnet; I Turesson; J Nyman; John H Peacock; Alison M Dunning; Bruce A J Ponder; S P Jackson
Comparison of DNA repair protein expression and activities between human fibroblast cell lines with different radiosensitivities.
International journal of cancer. Journal international du cancer 2000;85(6):845-9.
2000: Sunil R Lakhani; barry gusterson; Jocelyne Jacquemier; John P Sloane; T J Anderson; M J van de Vijver; D Venter; A Freeman; A Antoniou; Lesley McGuffog; E Smyth; C M Steel; N Haites; R J Scott; David E Goldgar; Susan L Neuhausen; PA Daly; W Ormiston; Ross McManus; Siegfried Scherneck; Bruce A J Ponder; P Andrew Futreal; Julian Peto; D Stoppa-Lyonnet; Y J Bignon; Michael R Stratton
The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):782-9.
2000: Simon A Gayther; SJ Batley; L Linger; Andrew J Bannister; K Thorpe; Suet-Feung Chin; Yataro Daigo; P Russell; A Wilson; HM Sowter; J D Delhanty; Bruce A J Ponder; Tony Kouzarides; Carlos Caldas
Mutations truncating the EP300 acetylase in human cancers.
Nature genetics 2000;24(3):300-3.
2000: Catherine S Healey; Alison M Dunning; Francine Durocher; Dawn M Teare; Paul D P Pharoah; Robert N Luben; Douglas F Easton; Bruce A J Ponder
Polymorphisms in the human aromatase cytochrome P450 gene (CYP19) and breast cancer risk.
Carcinogenesis 2000;21(2):189-93.
2000: Antonis C Antoniou; Simon A Gayther; JF Stratton; Bruce A J Ponder; Douglas F Easton
Risk models for familial ovarian and breast cancer.
Genetic epidemiology 2000;18(2):173-90.
1999: Carlos Caldas; Fátima Carneiro; H T Lynch; J Yokota; G L Wiesner; S M Powell; Frank R Lewis; David Huntsman; P D Pharoah; Janusz A Jankowski; PM MacLeod; H Vogelsang; G Keller; K G Park; Frances M Richards; Eamonn R Maher; Simon A Gayther; Carla Oliveira; Nicola Grehan; D Wight; Raquel Seruca; franco roviello; Bruce A J Ponder; C E Jackson
Familial gastric cancer: overview and guidelines for management.
Journal of medical genetics 1999;36(12):873-80.
1999: JF Stratton; Debra A Thompson; Lynda Bobrow; N Dalal; Martin Gore; Tim BISHOP; I Scott; G Evans; P Daly; Douglas F Easton; Bruce A J Ponder
The genetic epidemiology of early-onset epithelial ovarian cancer: a population-based study.
American journal of human genetics 1999;65(6):1725-32.
1999: Alison M Dunning; Simon McBride; J Gregory; Francine Durocher; Nicola A Foster; Catherine S Healey; N Smith; Paul D P Pharoah; Robert N Luben; Douglas F Easton; Bruce A J Ponder
No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer.
Carcinogenesis 1999;20(11):2131-5.
1999: Alison M Dunning; Catherine S Healey; Paul D P Pharoah; M Dawn Teare; Bruce A J Ponder; Douglas F Easton
A systematic review of genetic polymorphisms and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(10):843-54.
1999: Simon A Gayther; P Russell; Patricia Harrington; Antonis C Antoniou; Douglas F Easton; Bruce A J Ponder
The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes.
American journal of human genetics 1999;65(4):1021-9.
1999: F Carlomagno; J Chang-Claude; Alison M Dunning; Bruce A J Ponder
Determination of the frequency of the common 657Del5 Nijmegen breakage syndrome mutation in the German population: no association with risk of breast cancer.
Genes, chromosomes & cancer 1999;25(4):393-5.
1999: Bruce A J Ponder
Costs, benefits and limitations of genetic testing for cancer risk.
British journal of cancer 1999;80 Suppl 1():46-50.
1999: H Lee; A H Trainer; LS Friedman; FC Thistlethwaite; Martin J Evans; Bruce A J Ponder; Ashok R Venkitaraman
Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.
Molecular cell 1999;4(1):1-10.
1999: Susan J Ramus; Lynda Bobrow; Paul D P Pharoah; D S Finnigan; Ami Fishman; M Altaras; Patricia A Harrington; Simon A Gayther; Bruce A J Ponder; LS Friedman
Increased frequency of TP53 mutations in BRCA1 and BRCA2 ovarian tumours.
Genes, chromosomes & cancer 1999;25(2):91-6.
1999: Bruce A J Ponder
The phenotypes associated with ret mutations in the multiple endocrine neoplasia type 2 syndrome.
Cancer research 1999;59(7 Suppl):1736s-1741s; discussion 1742s.
1999: B Csokay; Nóra Udvarhelyi; Zoltán Sulyok; I Besznyak; Susan J Ramus; Bruce A J Ponder; Edith Olah
High frequency of germ-line BRCA2 mutations among Hungarian male breast cancer patients without family history.
Cancer research 1999;59(5):995-8.
1999: Paul D P Pharoah; Douglas F Easton; D L Stockton; Simon A Gayther; Bruce A J Ponder
Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group.
Cancer research 1999;59(4):868-71.
1998: Charis Eng; Gerry A Thomas; Donna Neuberg; L M Mulligan; Catherine S Healey; Carol Houghton; A Frilling; F Raue; E Dillwyn Williams; Bruce A J Ponder
Mutation of the RET proto-oncogene is correlated with RET immunostaining in subpopulations of cells in sporadic medullary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 1998;83(12):4310-3.
1998: Simon A Gayther; Paul D P Pharoah; Bruce A J Ponder
The genetics of inherited breast cancer.
Journal of mammary gland biology and neoplasia 1998;3(4):365-76.
1998: Simon A Gayther; K L Gorringe; Susan J Ramus; David Huntsman; franco roviello; Nicola Grehan; José Carlos Machado; E Pinto; Raquel Seruca; K Halling; PM MacLeod; S M Powell; C E Jackson; Bruce A J Ponder; Carlos Caldas
Identification of germ-line E-cadherin mutations in gastric cancer families of European origin.
Cancer research 1998;58(18):4086-9.
1998: Simon A Gayther; Bruce A J Ponder
Clues to the function of the tumour susceptibility gene BRCA2.
Disease markers 1998;14(1):1-8.
1998: Alison M Dunning; Catherine S Healey; Paul D P Pharoah; Nicola A Foster; Julian M Lipscombe; Karen Redman; Douglas F Easton; Nicholas E Day; Bruce A J Ponder
No association between a polymorphism in the steroid metabolism gene CYP17 and risk of breast cancer.
British journal of cancer 1998;77(11):2045-7.
1998: Susan L Neuhausen; A K Godwin; R Gershoni-Baruch; E Schubert; Judy E Garber; D Stoppa-Lyonnet; Edith Olah; B Csokay; OM Serova; Fiona Lalloo; A Osorio; Michael Stratton; Kenneth Offit; J Boyd; MA Caligo; R J Scott; A Schofield; E Teugels; M Schwab; Lisa A Cannon-Albright; D Timothy Bishop; Douglas Easton; J Benitez; Mary-Claire King; Bruce A J Ponder; B Weber; Peter Devilee; Ake Borg; Steven A Narod; David E Goldgar
Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study.
American journal of human genetics 1998;62(6):1381-8.
1998: Italia Bongarzone; E Vigano; Luisella Alberti; Maria Grazia Borrello; Barbara Pasini; Angela Greco; Piera Mondellini; D P Smith; Bruce A J Ponder; Giovanni Romeo; Marco A Pierotti
Full activation of MEN2B mutant RET by an additional MEN2A mutation or by ligand GDNF stimulation.
Oncogene 1998;16(18):2295-301.
1998: J F Stratton; Paul Pharoah; S K Smith; Douglas Easton; Bruce A J Ponder
A systematic review and meta-analysis of family history and risk of ovarian cancer.
British journal of obstetrics and gynaecology 1998;105(5):493-9.
1998: KA de Foy; Simon A Gayther; W H Colledge; S Crockett; I V Scott; Martin J Evans; Bruce A J Ponder
Mutation analysis of the c-mos proto-oncogene in human ovarian teratomas.
British journal of cancer 1998;77(10):1642-4.
1998: LS Friedman; FC Thistlethwaite; Ketan J Patel; VP Yu; H Lee; Ashok R Venkitaraman; K J Abel; Mark B L Carlton; S M Hunter; William H Colledge; Martin J Evans; Bruce A J Ponder
Thymic lymphomas in mice with a truncating mutation in Brca2.
Cancer research 1998;58(7):1338-43.
1998: Roswitha Pfragner; Annemarie Behmel; D P Smith; Bruce A J Ponder; Gernot Wirnsberger; I Rinner; S Porta; T Henn; Bruno Niederle
First continuous human pheochromocytoma cell line: KNA. Biological, cytogenetic and molecular characterization of KNA cells.
Journal of neurocytology 1998;27(3):175-86.
1998: CM Phelan; Ake Borg; Marguerite Cuny; DN Crichton; T Baldersson; T I Andersen; MA Caligo; Rosette Lidereau; Annika Lindblom; S Seitz; D Kelsell; U Hamann; P Rio; S Thorlacius; Janos Papp; Edith Olah; Bruce A J Ponder; Y J Bignon; Siegfried Scherneck; Rosa B Barkardottir; A L Borresen-Dale; Jorunn E Eyfjörd; Charles Theillet; Alastair Thompson; Catharina Larsson
Consortium study on 1280 breast carcinomas: allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters.
Cancer research 1998;58(5):1004-12.
1998: D Ford; Douglas F Easton; Michael Stratton; Steven A Narod; David E Goldgar; Peter Devilee; Tim BISHOP; B Weber; G Lenoir; Jenny Chang-Claude; H Sobol; MD Teare; Jeffery Struewing; Adalgeir Arason; Siegfried Scherneck; Julian Peto; T R Rebbeck; P Tonin; Susan L Neuhausen; Rosa B Barkardottir; Jorunn E Eyfjord; H Lynch; Bruce A J Ponder; Simon A Gayther; M Zelada-Hedman
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
American journal of human genetics 1998;62(3):676-89.
1998: Ketan J Patel; VP Yu; H Lee; A Corcoran; FC Thistlethwaite; Martin J Evans; William H Colledge; LS Friedman; Bruce A J Ponder; Ashok R Venkitaraman
Involvement of Brca2 in DNA repair.
Molecular cell 1998;1(3):347-57.
1998: Barry R Davies; SD Worsley; Bruce A J Ponder
Expression of E-cadherin, alpha-catenin and beta-catenin in normal ovarian surface epithelium and epithelial ovarian cancers.
Histopathology 1998;32(1):69-80.
1998: Bruce A J Ponder
Inherited predisposition to breast cancer.
Biochemical Society symposium 1998;63():223-30.
1998: Barry R Davies; Nelly Auersperg; SD Worsley; Bruce A J Ponder
Transfection of rat ovarian surface epithelium with erb-B2/neu induces transformed phenotypes in vitro and the tumorigenic phenotype in vivo.
The American journal of pathology 1998;152(1):297-306.
1997: Simon A Gayther; P Barski; SJ Batley; L Li; KA de Foy; S N Cohen; Bruce A J Ponder; Carlos Caldas
Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours.
Oncogene 1997;15(17):2119-26.
1997: DP Smith; Carol Houghton; Bruce A J Ponder
Germline mutation of RET codon 883 in two cases of de novo MEN 2B.
Oncogene 1997;15(10):1213-7.
1997: Paul D P Pharoah; Nicholas E Day; Stephen W Duffy; Douglas F Easton; Bruce A J Ponder
Family history and the risk of breast cancer: a systematic review and meta-analysis.
International journal of cancer. Journal international du cancer 1997;71(5):800-9.
1997: Carlos Caldas; Bruce A J Ponder
Cancer genes and molecular oncology in the clinic.
Lancet 1997;349 Suppl 2():SII16-8.
1997: Susan J Ramus; Zsofia Kote-Jarai; LS Friedman; M van der Looij; Simon A Gayther; B Csokay; Bruce A J Ponder; Edith Olah
Analysis of BRCA1 and BRCA2 mutations in Hungarian families with breast or breast-ovarian cancer.
American journal of human genetics 1997;60(5):1242-6.
1997: Simon A Gayther; Patricia Harrington; P Russell; G Kharkevich; R F Garkavtseva; Bruce A J Ponder
Frequently occurring germ-line mutations of the BRCA1 gene in ovarian cancer families from Russia.
American journal of human genetics 1997;60(5):1239-42.
1997: Jonathon Milner; Bruce A J Ponder; Luke Hughes-Davies; M Seltmann; Tony Kouzarides
Transcriptional activation functions in BRCA2.
Nature 1997;386(6627):772-3.
1997: JF Stratton; Simon A Gayther; P Russell; J Dearden; Martin Gore; P Blake; Douglas Easton; Bruce A J Ponder
Contribution of BRCA1 mutations to ovarian cancer.
The New England journal of medicine 1997;336(16):1125-30.
1997: Simon A Gayther; Bruce A J Ponder
Mutations of the BRCA1 and BRCA2 genes and the possibilities for predictive testing.
Molecular medicine today 1997;3(4):168-74.
1997: M J Lorenzo; G D Gish; Carol Houghton; T J Stonehouse; T Pawson; Bruce A J Ponder; DP Smith
RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2.
Oncogene 1997;14(7):763-71.
1997: Alison M Dunning; M Chiano; N R Smith; J Dearden; M Gore; S Oakes; C Wilson; Michael Stratton; Julian Peto; Douglas Easton; David Clayton; Bruce A J Ponder
Common BRCA1 variants and susceptibility to breast and ovarian cancer in the general population.
Human molecular genetics 1997;6(2):285-9.
1997: SD Worsley; Bruce A J Ponder; Barry R Davies
Overexpression of cyclin D1 in epithelial ovarian cancers.
Gynecologic oncology 1997;64(2):189-95.
1997: LS Friedman; Simon A Gayther; T Kurosaki; D Gordon; B Noble; G Casey; Bruce A J Ponder; H Anton-Culver
Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population.
American journal of human genetics 1997;60(2):313-9.
1997: Simon A Gayther; J Mangion; P Russell; Sheila Seal; Rita Barfoot; Bruce A J Ponder; Michael R Stratton; Douglas Easton
Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene.
Nature genetics 1997;15(1):103-5.
1997: Susan J Ramus; LS Friedman; Simon A Gayther; Bruce A J Ponder; Lynda Bobrow; M van der Looji; Janos Papp; Edith Olah
A breast/ovarian cancer patient with germline mutations in both BRCA1 and BRCA2.
Nature genetics 1997;15(1):14-5.
1996: Janos Papp; B Csokay; P Bosze; Z Zalay; J Toth; Bruce A J Ponder; Edith Olah
Allele loss from large regions of chromosome 17 is common only in certain histological subtypes of ovarian carcinomas.
British journal of cancer 1996;74(10):1592-7.
1996: Sylvie Mazoyer; Alison M Dunning; OM Serova; J Dearden; Nadine Puget; Catherine S Healey; Simon A Gayther; J Mangion; Michael R Stratton; Henry T Lynch; David E Goldgar; Bruce A J Ponder; Gilbert M Lenoir
A polymorphic stop codon in BRCA2.
Nature genetics 1996;14(3):253-4.
1996: N J Froggatt; C Brassett; D J Koch; D G Evans; S V Hodgson; Bruce A J Ponder; Eamonn R Maher
Mutation screening of MSH2 and MLH1 mRNA in hereditary non-polyposis colon cancer syndrome.
Journal of medical genetics 1996;33(9):726-30.
1996: K A Foster; Patricia Harrington; J Kerr; P Russell; R A DiCioccio; I V Scott; I Jacobs; G Chenevix-Trench; Bruce A J Ponder; Simon A Gayther
Somatic and germline mutations of the BRCA2 gene in sporadic ovarian cancer.
Cancer research 1996;56(16):3622-5.
1996: Charis Eng; K A Foster; Catherine S Healey; Carol Houghton; Simon A Gayther; Lois M Mulligan; Bruce A J Ponder
Mutation analysis of the c-mos proto-oncogene and the endothelin-B receptor gene in medullary thyroid carcinoma and phaeochromocytoma.
British journal of cancer 1996;74(3):339-41.
1996: Charis Eng; Lois M Mulligan; Catherine S Healey; Carol Houghton; A Frilling; F Raue; Gerry A Thomas; Bruce A J Ponder
Heterogeneous mutation of the RET proto-oncogene in subpopulations of medullary thyroid carcinoma.
Cancer research 1996;56(9):2167-70.
1996: Deborah J Marsh; Scott D Andrew; Charis Eng; Diana L Learoyd; A G Capes; R Pojer; A L Richardson; Carol Houghton; Lois M Mulligan; Bruce A J Ponder; Bruce G Robinson
Germline and somatic mutations in an oncogene: RET mutations in inherited medullary thyroid carcinoma.
Cancer research 1996;56(6):1241-3.
1996: Simon A Gayther; Patricia Harrington; P Russell; G Kharkevich; R F Garkavtseva; Bruce A J Ponder
Rapid detection of regionally clustered germ-line BRCA1 mutations by multiplex heteroduplex analysis. UKCCCR Familial Ovarian Cancer Study Group.
American journal of human genetics 1996;58(3):451-6.
1996: CM Phelan; Timothy R Rebbeck; Barbara L Weber; Peter Devilee; M H Ruttledge; H T Lynch; Gilbert M Lenoir; Michael R Stratton; D F Easton; Bruce A J Ponder; Lisa A Cannon-Albright; Catharina Larsson; D E Goldgar; Steven A Narod
Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus.
Nature genetics 1996;12(3):309-11.
1996: Y F Mak; Bruce A J Ponder
RET oncogene.
Current opinion in genetics & development 1996;6(1):82-6.
1996: Susan L Neuhausen; Sylvie Mazoyer; L Friedman; Michael Stratton; Kenneth Offit; A Caligo; Gail Tomlinson; Lisa A Cannon-Albright; D Timothy Bishop; D Kelsell; E Solomon; B Weber; Fergus J. Couch; Jeffery Struewing; Patricia N Tonin; Francine Durocher; Steven A Narod; Mark H Skolnick; G Lenoir; OM Serova; Bruce A J Ponder; D Stoppa-Lyonnet; Douglas Easton; Mary-Claire King; David E Goldgar
Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study.
American journal of human genetics 1996;58(2):271-80.
1996: Bruce A J Ponder; D Smith
The MEN II syndromes and the role of the ret proto-oncogene.
Advances in cancer research 1996;70():179-222.
1995: Simon A Gayther; W Warren; Sylvie Mazoyer; P A Russell; Patricia Harrington; M Chiano; Sheila Seal; Rifat A Hamoudi; E J van Rensburg; Alison M Dunning; R Love; G Evans; Douglas Easton; D Clayton; Michael R Stratton; Bruce A J Ponder
Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation.
Nature genetics 1995;11(4):428-33.
1995: R S Cornelis; Susan L Neuhausen; O Johansson; Adalgeir Arason; D Kelsell; Bruce A J Ponder; Patricia N Tonin; U Hamann; A Lindblom; P Lalle
High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCAl-linked families. The Breast Cancer Linkage Consortium.
Genes, chromosomes & cancer 1995;13(3):203-10.
1995: Charis Eng; Lois M Mulligan; D P Smith; Catherine S Healey; A Frilling; F Raue; H P Neumann; M A Ponder; Bruce A J Ponder
Low frequency of germline mutations in the RET proto-oncogene in patients with apparently sporadic medullary thyroid carcinoma.
Clinical endocrinology 1995;43(1):123-7.
1995: Sylvie Mazoyer; Simon A Gayther; M A Nagai; S A Smith; Alison M Dunning; E J van Rensburg; H Albertsen; Raymond White; Bruce A J Ponder
A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dIg-A.
Genomics 1995;28(1):25-31.
1995: N J Froggatt; J Koch; R Davies; D G Evans; A Clamp; O W Quarrell; J Weissenbach; S V Hodgson; Bruce A J Ponder; David Barton
Genetic linkage analysis in hereditary non-polyposis colon cancer syndrome.
Journal of medical genetics 1995;32(5):352-7.
1995: M J Lorenzo; Charis Eng; Lois M Mulligan; T J Stonehouse; Catherine S Healey; Bruce A J Ponder; D P Smith
Multiple mRNA isoforms of the human RET proto-oncogene generated by alternate splicing.
Oncogene 1995;10(7):1377-83.
1995: N J Froggatt; Johanna A Joyce; R Davies; D Gareth; R Evans; Bruce A J Ponder; David Barton; Eamonn R Maher
A frequent hMSH2 mutation in hereditary non-polyposis colon cancer syndrome.
Lancet 1995;345(8951):727.
1995: Charis Eng; D P Smith; Lois M Mulligan; Catherine S Healey; Marketa Zvelebil; T J Stonehouse; M A Ponder; C E Jackson; M D Waterfield; Bruce A J Ponder
A novel point mutation in the tyrosine kinase domain of the RET proto-oncogene in sporadic medullary thyroid carcinoma and in a family with FMTC.
Oncogene 1995;10(3):509-13.
1995: Bruce A J Ponder
Mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2.
Cancer surveys 1995;25():195-205.
1994: Gerald L Feldman; M Kambouris; Gary B Talpos; Lois M Mulligan; Bruce A J Ponder; C E Jackson
Clinical value of direct DNA analysis of the RET proto-oncogene in families with multiple endocrine neoplasia type 2A.
Surgery 1994;116(6):1042-7.
1994: E Gardner; Lois M Mulligan; Charis Eng; Catherine S Healey; J B Kwok; M A Ponder; Bruce A J Ponder
Haplotype analysis of MEN 2 mutations.
Human molecular genetics 1994;3(10):1771-4.
1994: Charis Eng; Victoria Murday; S Seal; S Mohammed; Shirley V Hodgson; M A Chaudary; I S Fentiman; Bruce A J Ponder; R A Eeles
Cowden syndrome and Lhermitte-Duclos disease in a family: a single genetic syndrome with pleiotropy?
Journal of medical genetics 1994;31(6):458-61.
1994: Lois M Mulligan; Charis Eng; Catherine S Healey; M A Ponder; Gerald L Feldman; P Li; C E Jackson; Bruce A J Ponder
A de novo mutation of the RET proto-oncogene in a patient with MEN 2A.
Human molecular genetics 1994;3(6):1007-8.
1994: Bruce A J Ponder
The gene causing multiple endocrine neoplasia type 2 (MEN 2).
Annals of medicine 1994;26(3):199-203.
1994: R McMahon; Lois M Mulligan; Catherine S Healey; S J Payne; M Ponder; Malcolm A Ferguson-Smith; David Barton; Bruce A J Ponder
Direct, non-radioactive detection of mutations in multiple endocrine neoplasia type 2A families.
Human molecular genetics 1994;3(4):643-6.
1994: Charis Eng; Michael Stratton; Bruce A J Ponder; Victoria Murday; Douglas Easton; N Sacks; M Watson; R Eeles
Familial cancer syndromes.
Lancet 1994;343(8899):709-13.
1994: Richard Wooster; Anne-Marie Cleton-Jansen; N Collins; J Mangion; R S Cornelis; Colin S Cooper; Barry A Gusterson; Bruce A J Ponder; A von Deimling; O D Wiestler
Instability of short tandem repeats (microsatellites) in human cancers.
Nature genetics 1994;6(2):152-6.
1994: D P Smith; Charis Eng; Bruce A J Ponder
Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes and Hirschsprung disease.
Journal of cell science. Supplement 1994;18():43-9.
1993: Michael S Jackson; Predrag Slijepcevic; Bruce A J Ponder
The organisation of repetitive sequences in the pericentromeric region of human chromosome 10.
Nucleic acids research 1993;21(25):5865-74.
1993: S A Smith; Bruce A J Ponder
Predisposing genes in breast and ovarian cancer: an overview.
Tumori 1993;79(5):291-6.
1993: J B Kwok; E Gardner; J P Warner; Bruce A J Ponder; Lois M Mulligan
Structural analysis of the human ret proto-oncogene using exon trapping.
Oncogene 1993;8(9):2575-82.
1993: Richard Wooster; D Ford; J Mangion; Bruce A J Ponder; J Peto; Douglas F Easton; Michael R Stratton
Absence of linkage to the ataxia telangiectasia locus in familial breast cancer.
Human genetics 1993;92(1):91-4.
1993: Douglas F Easton; M A Ponder; S M Huson; Bruce A J Ponder
An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): evidence for modifying genes.
American journal of human genetics 1993;53(2):305-13.
1993: Charis Eng; Bruce A J Ponder
The role of gene mutations in the genesis of familial cancers.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(10):910-9.
1993: Donald R Love; E Gardner; Bruce A J Ponder
A polymorphic dinucleotide repeat at the ZNF22 locus.
Human molecular genetics 1993;2(4):491.
1993: Donald R Love; E Gardner; Bruce A J Ponder
A polymorphic dinucleotide repeat at the D10S141 locus.
Human molecular genetics 1993;2(4):491.
1993: S A Smith; Douglas F Easton; D Ford; Julian Peto; K Anderson; D Averill; Michael Stratton; M Ponder; C Pye; Bruce A J Ponder
Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21.
American journal of human genetics 1993;52(4):767-76.
1993: A Tunnacliffe; L Liu; J K Moore; MA Leversha; Michael S Jackson; L Papi; Malcolm A Ferguson-Smith; H J Thiesen; Bruce A J Ponder
Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution.
Nucleic acids research 1993;21(6):1409-17.
1993: Ian J Jacobs; S A Smith; Roger W Wiseman; P Andrew Futreal; T Harrington; R J Osborne; Vanessa Leech; A Molyneux; Andrew Berchuck; Bruce A J Ponder
A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus.
Cancer research 1993;53(6):1218-21.
1993: S E Mole; Lois M Mulligan; Catherine S Healey; Bruce A J Ponder; A Tunnacliffe
Localisation of the gene for multiple endocrine neoplasia type 2A to a 480 kb region in chromosome band 10q11.2.
Human molecular genetics 1993;2(3):247-52.
1993: Lois M Mulligan; E Gardner; B A Smith; C G Mathew; Bruce A J Ponder
Genetic events in tumour initiation and progression in multiple endocrine neoplasia type 2.
Genes, chromosomes & cancer 1993;6(3):166-77.
1993: S E Mole; Michael S Jackson; T Tokino; Y Nakamura; Bruce A J Ponder
Assignment of fifty-four cosmid clones to five regions of chromosome 10.
Genomics 1993;15(2):457-8.
1993: Bruce A J Ponder
Genetic screening for multiple endocrine neoplasia type 2.
Experimental and clinical endocrinology 1993;101(1):53-6.
1993: H Telenius; D de Vos; Elisabeth Blennow; L R Willat; Bruce A J Ponder; Nigel P Carter
Chromatid contamination can impair the purity of flow-sorted metaphase chromosomes.
Cytometry 1993;14(1):97-101.
1992: Elisabeth Blennow; H Telenius; Catharina Larsson; D de Vos; S Bajalica; Bruce A J Ponder; Magnus Nordenskjöld
Complete characterization of a large marker chromosome by reverse and forward chromosome painting.
Human genetics 1992;90(4):371-4.
1992: Lois M Mulligan; E Gardner; Bruce A J Ponder
An SphI polymorphism at the ZNF22 locus.
Human molecular genetics 1992;1(7):551.
1992: J A Chambers; E Gardner; R Hauptmann; Bruce A J Ponder; Lois M Mulligan
TaqI polymorphisms at the annexin VIII locus (ANX8).
Human molecular genetics 1992;1(7):550.
1992: Lois M Mulligan; E Gardner; Bruce A J Ponder
An SphI polymorphism at the vinculin locus (VCL).
Human molecular genetics 1992;1(7):550.
1992: Richard Wooster; J Mangion; R Eeles; S Smith; M Dowsett; D Averill; P Barrett-Lee; Douglas F Easton; Bruce A J Ponder; Michael R Stratton
A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome.
Nature genetics 1992;2(2):132-4.
1992: S A Smith; Douglas F Easton; D G Evans; Bruce A J Ponder
Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome.
Nature genetics 1992;2(2):128-31.
1992: Michael S Jackson; S E Mole; Bruce A J Ponder
Characterisation of a boundary between satellite III and alphoid sequences on human chromosome 10.
Nucleic acids research 1992;20(18):4781-7.
1992: L Papi; A Tunnacliffe; Bruce A J Ponder
Dinucleotide repeat polymorphism at the RBP3 locus in chromosome band 10q11.2.
Human molecular genetics 1992;1(6):450.
1992: Lois M Mulligan; E Gardner; H Telenius; Bruce A J Ponder
Complementary physical and genetic techniques map the vinculin (VCL) gene on chromosome 10q.
Genomics 1992;13(4):1347-9.
1992: M F Rousseau-Merck; A Tunnacliffe; Roland Berger; Bruce A J Ponder; H J Thiesen
A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10.
Genomics 1992;13(3):845-8.
1992: H Telenius; Nigel P Carter; C E Bebb; Magnus Nordenskjöld; Bruce A J Ponder; A Tunnacliffe
Degenerate oligonucleotide-primed PCR: general amplification of target DNA by a single degenerate primer.
Genomics 1992;13(3):718-25.
1992: Bruce A J Ponder
Neurofibromatosis: from gene to phenotype.
Seminars in cancer biology 1992;3(3):115-20.
1992: Weiming XU; Lois M Mulligan; M A Ponder; L Liu; B A Smith; C G Mathew; Bruce A J Ponder
Loss of NF1 alleles in phaeochromocytomas from patients with type I neurofibromatosis.
Genes, chromosomes & cancer 1992;4(4):337-42.
1992: Bruce A J Ponder
Molecular genetics of cancer.
BMJ (Clinical research ed.) 1992;304(6836):1234-6.
1992: William Warren; R A Eeles; Bruce A J Ponder; Douglas F Easton; D Averill; M A Ponder; K Anderson; A M Evans; R DeMars; R Love
No evidence for germline mutations in exons 5-9 of the p53 gene in 25 breast cancer families.
Oncogene 1992;7(5):1043-6.
1992: H Telenius; A H Pelmear; A Tunnacliffe; Nigel P Carter; Annemarie Behmel; Malcolm A Ferguson-Smith; Magnus Nordenskjöld; Roswitha Pfragner; Bruce A J Ponder
Cytogenetic analysis by chromosome painting using DOP-PCR amplified flow-sorted chromosomes.
Genes, chromosomes & cancer 1992;4(3):257-63.
1992: Douglas J Winton; L Howard; Bruce A J Ponder
Possible non-functional crypts in small intestine defined using mouse aggregation chimaeras.
Epithelial cell biology 1992;1(2):59-64.
1992: D L Duffy; A M Macdonald; Douglas F Easton; Bruce A J Ponder; N G Martin
Is the genetics of moliness simply the genetics of sun exposure? A path analysis of nevus counts and risk factors in British twins.
Cytogenetics and cell genetics 1992;59(2-3):194-6.
1992: Douglas F Easton; G M Cox; A M Macdonald; Bruce A J Ponder
The study of nevi in British twins: study design and description of the data set.
Cytogenetics and cell genetics 1992;59(2-3):165-6.
1992: X Weiming; Q Yu; L Lizhi; M Ponder; M Wallace; X Gangfeng; Bruce A J Ponder
Molecular analysis of neurofibromatosis type 1 mutations.
Human mutation 1992;1(6):474-7.
1991: Douglas F Easton; G M Cox; A M Macdonald; Bruce A J Ponder
Genetic susceptibility to naevi--a twin study.
British journal of cancer 1991;64(6):1164-7.
1991: Lois M Mulligan; E Gardner; L Papi; Bruce A J Ponder
A new polymorphism in the ret protooncogene (RET).
Nucleic acids research 1991;19(20):5795.
1991: E Gardner; B Rydberg; Peter Karran; Bruce A J Ponder
Localization of the human O6-methylguanine-DNA methyltransferase gene to chromosome 10q24.33-qter.
Genomics 1991;11(2):475-6.
1991: Weiming XU; L Liu; D M Black; Bruce A J Ponder
A BglII polymorphism in the human NF1 gene.
Nucleic acids research 1991;19(17):4798.
1991: Weiming XU; L Liu; M Ponder; Bruce A J Ponder
A TaqI polymorphism in the human NF1 gene.
Nucleic acids research 1991;19(16):4570.
1991: Weiming XU; L Liu; Bruce A J Ponder
A BamHI polymorphism in the human EVI2A gene (human homolog of the murine gene Evi-2).
Nucleic acids research 1991;19(9):2520.
1991: C G Mathew; Douglas F Easton; Y Nakamura; Bruce A J Ponder
Presymptomatic screening for multiple endocrine neoplasia type 2A with linked DNA markers. The MEN 2A International Collaborative Group.
Lancet 1991;337(8732):7-11.
1990: Douglas J Winton; Nigel J Gooderham; Alan R Boobis; D S Davies; Bruce A J Ponder
Mutagenesis of mouse intestine in vivo using the Dlb-1 specific locus test: studies with 1,2-dimethylhydrazine, dimethylnitrosamine, and the dietary mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Cancer research 1990;50(24):7992-6.
1990: Eamonn R Maher; E Bentley; J R W Yates; David Barton; A Jennings; I W Fellows; M A Ponder; Bruce A J Ponder; C Benjamin; R Harris
Mapping of von Hippel-Lindau disease to chromosome 3p confirmed by genetic linkage analysis.
Journal of the neurological sciences 1990;100(1-2):27-30.
1990: R A Norum; R G Lafreniere; L W O'Neal; T F Nikolai; J P Delaney; J C Sisson; H Sobol; G M Lenoir; Bruce A J Ponder; H F Willard
Linkage of the multiple endocrine neoplasia type 2B gene (MEN2B) to chromosome 10 markers linked to MEN2A.
Genomics 1990;8(2):313-7.
1990: Douglas J Winton; Bruce A J Ponder
Stem-cell organization in mouse small intestine.
Proceedings. Biological sciences / The Royal Society 1990;241(1300):13-8.
1990: Bruce A J Ponder
Inherited predisposition to cancer.
Trends in genetics : TIG 1990;6(7):213-8.
1990: H Telenius; C G Mathew; Y Nakamura; D F Easton; J Clark; H P Neumann; W H Ziegler; A Schinzel; Bruce A J Ponder
Application of linked DNA markers to screening families with multiple endocrine neoplasia type 2A.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1990;16(2):134-40.
1990: Bruce A J Ponder
Prospects for genetic diagnosis of inherited predisposition to cancer.
Trends in biotechnology 1990;8(4):98-104.
1990: Bruce A J Ponder
Multiple endocrine neoplasia type 2.
BMJ (Clinical research ed.) 1990;300(6723):484-5.
1990: D Jadayel; P Fain; Meena Upadhyaya; M A Ponder; S M Huson; J Carey; A Fryer; C G Mathew; David Barker; Bruce A J Ponder
Paternal origin of new mutations in von Recklinghausen neurofibromatosis.
Nature 1990;343(6258):558-9.
1990: H Telenius; J Clark; E Marcus; Nicola J Royle; Alec J Jeffreys; Bruce A J Ponder; C G Mathew
Minisatellite DNA profiles: rapid sample identification in linkage analysis.
Human heredity 1990;40(2):77-80.
1989: D J Winton; John Peacock; Bruce A J Ponder
Effect of gamma radiation at high- and low-dose rate on a novel in vivo mutation assay in mouse intestine.
Mutagenesis 1989;4(5):404-6.
1989: D J Winton; M A Blount; Bruce A J Ponder
Polyclonal origin of mouse skin papillomas.
British journal of cancer 1989;60(1):59-63.
1989: R M Landsvater; C G Mathew; B A Smith; E M Marcus; Gerard te Meerman; Cornelis J M Lips; R A Geerdink; Y Nakamura; Bruce A J Ponder; Charles H C M Buys
Development of multiple endocrine neoplasia type 2A does not involve substantial deletions of chromosome 10.
Genomics 1989;4(3):246-50.
1989: Douglas F Easton; M A Ponder; T Cummings; R F Gagel; H H Hansen; S Reichlin; A H Tashjian; M Telenius-Berg; Bruce A J Ponder
The clinical and screening age-at-onset distribution for the MEN-2 syndrome.
American journal of human genetics 1989;44(2):208-15.
1989: M Telenius-Berg; M A Ponder; B Berg; Bruce A J Ponder; S Werner
Quality of life after bilateral adrenalectomy in MEN 2.
Henry Ford Hospital medical journal 1989;37(3-4):160-3.
1988: E M Marcus; B A Smith; H Telenius; R M Landsvater; Charles H C M Buys; S Ferrari; Bruce A J Ponder; C G Mathew
BclI RFLP for the human vimentin gene.
Nucleic acids research 1988;16(18):9068.
1988: D J Winton; M A Blount; Bruce A J Ponder
A clonal marker induced by mutation in mouse intestinal epithelium.
Nature 1988;333(6172):463-6.
1988: Bruce A J Ponder; Nick Finer; R Coffey; C L Harmer; M Maisey; M G Ormerod; Marcus E Pembrey; M A Ponder; P Rosswick; S Shalet
Family screening in medullary thyroid carcinoma presenting without a family history.
The Quarterly journal of medicine 1988;67(252):299-308.
1988: K S Chin; C G Mathew; S L Fong; C D Bridges; Bruce A J Ponder
Styl RFLP recognised by a human IRBP cDNA localised to chromosome 10.
Nucleic acids research 1988;16(4):1645.
1988: Bruce A J Ponder; M A Ponder; R Coffey; Marcus E Pembrey; R F Gagel; M Telenius-Berg; P Semple; Douglas F Easton
Risk estimation and screening in families of patients with medullary thyroid carcinoma.
Lancet 1988;1(8582):397-401.
1987: Mark H Skolnick; Bruce A J Ponder; B Seizinger
Linkage of NF1 to 12 chromosome 17 markers: a summary of eight concurrent reports.
Genomics 1987;1(4):382-3.
1987: Bruce A J Ponder
Familial cancer: opportunities for clinical practice and research.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 1987;13(6):463-73.
1987: C G Mathew; K Thorpe; D F Easton; C Carter; C Wallis; Z Wong; A J Jeffreys; Bruce A J Ponder
Linkage analysis of British and Indian families with Von Recklinghausen neurofibromatosis.
Journal of medical genetics 1987;24(9):524-6.
1987: C G Mathew; B A Smith; K Thorpe; Z Wong; Nicola J Royle; Alec J Jeffreys; Bruce A J Ponder
Deletion of genes on chromosome 1 in endocrine neoplasia.
Nature 1987;328(6130):524-6.
1987: G H Schmidt; M A Blount; Bruce A J Ponder
Immunochemical demonstration of the clonal organization of chimaeric mouse epidermis.
Development (Cambridge, England) 1987;100(3):535-41.
1987: Bruce A J Ponder; A J Jeffreys; N E Hartley; C Carter; Douglas F Easton; H Telenius; M Telenius-Berg
Application of minisatellite DNA probes to linkage in MEN-2.
Henry Ford Hospital medical journal 1987;35(2-3):161-3.
1987: C Carter; Douglas F Easton; C G Mathew; G Welander; H Telenius; M Telenius-Berg; Bruce A J Ponder
Exclusion of linkage of loci on chromosome 19 with multiple endocrine neoplasia, type 2.
Cytogenetics and cell genetics 1987;45(1):33-7.