FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Prem Ponka

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Co-author Network

Publications

TOP 3
Marc R Mikhael; Sameer Apte; Shan Soe-Lin; Prem Ponka
Nitrogen monoxide inhibits haem synthesis in mouse reticulocytes.
Megan Whitnall; Federica Saletta; Tim G St Pierre; Yohan Suryo Rahmanto; Adam J Fleming; Lucía Gutiérrez; Michael L-H Huang; Francisco J Lázaro; Hiu Chuen Lok; Marc R Mikhael; Prem Ponka; Des R Richardson
Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia.
Donghoon Yoon; Prem Ponka; Josef T Prchal
Hypoxia. 5. Hypoxia and hematopoiesis.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Prem Ponka (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Marc R Mikhael; Sameer Apte; Shan Soe-Lin; Prem Ponka
Nitrogen monoxide inhibits haem synthesis in mouse reticulocytes.
The Biochemical journal 2013;451(1):61-7.
2012: Megan Whitnall; Federica Saletta; Tim G St Pierre; Yohan Suryo Rahmanto; Adam J Fleming; Lucía Gutiérrez; Michael L-H Huang; Francisco J Lázaro; Hiu Chuen Lok; Marc R Mikhael; Prem Ponka; Des R Richardson
Identification of nonferritin mitochondrial iron deposits in a mouse model of Friedreich ataxia.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(50):20590-5.
2011: Donghoon Yoon; Prem Ponka; Josef T Prchal
Hypoxia. 5. Hypoxia and hematopoiesis.
American journal of physiology. Cell physiology 2011;300(6):C1215-22.
2010: Louay Mardini; Jadwiga Gasiorek; Anna Derjuga; Lucie Carrière; Matthias Schranzhofer; Barry H Paw; Prem Ponka; Volker Blank
Antagonistic roles of the ERK and p38 MAPK signalling pathways in globin expression, haem biosynthesis and iron uptake.
The Biochemical journal 2010;432(1):145-51.
2010: Marc Mikhael; Alex Sheftel; Prem Ponka
Ferritin does not donate its iron for haem synthesis in macrophages.
The Biochemical journal 2010;429(3):463-71.
2010: Shan Soe-Lin; Sameer S Apte; Marc R Mikhael; Lidia K Kayembe; Guangjun Nie; Prem Ponka
Both Nramp1 and DMT1 are necessary for efficient macrophage iron recycling.
Experimental hematology 2010;38(8):609-17.
2010: Des R Richardson; Darius J R Lane; Erika M Becker; Michael L-H Huang; Megan Whitnall; Alex D Sheftel; Yohan Suryo Rahmanto; Prem Ponka
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(24):10775-82.
2010: Monika Horvathova; Prem Ponka; Vladimir Divoky
Molecular basis of hereditary iron homeostasis defects.
Hematology (Amsterdam, Netherlands) 2010;15(2):96-111.
2010: Des R Richardson; Michael L-H Huang; Megan Whitnall; Erika M Becker; Prem Ponka; Yohan Suryo Rahmanto
The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich's ataxia.
Journal of molecular medicine (Berlin, Germany) 2010;88(4):323-9.
2009: Michael Li-Hsuan Huang; Erika M Becker; Megan Whitnall; Prem Ponka; Yohan Suryo Rahmanto; Des R Richardson
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16381-6.
2009: Gabriela Peslova; Jiri Petrak; Katerina Kuzelova; Ivan Hrdy; Petr Halada; Philip W Kuchel; Shan Soe-Lin; Prem Ponka; Robert Sutak; Erika Becker; Michael Li-Hsuan Huang; Des R Richardson; Yohan Suryo Rahmanto; Daniel Vyoral
Hepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in blood.
Blood 2009;113(24):6225-36.
2009: Shan Soe-Lin; Sameer S Apte; Billy Andriopoulos; Marc C Andrews; Matthias Schranzhofer; Tanya Kahawita; Daniel Garcia-Santos; Prem Ponka
Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5960-5.
2009: Suh Young Jeong; Khizr I Rathore; Katrin Schulz; Prem Ponka; paolo arosio; Samuel David
Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(3):610-9.
2009: Alex Sheftel; Des R Richardson; Josef Prchal; Prem Ponka
Mitochondrial iron metabolism and sideroblastic anemia.
Acta haematologica 2009;122(2-3):120-33.
2008: Khizr I Rathore; Bradley J Kerr; Adriana Redensek; Rubèn López-Vales; Suh Young Jeong; Prem Ponka; Samuel David
Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(48):12736-47.
2008: An-Sheng Zhang; Francois Canonne-Hergaux; Samantha Gruenheid; Philippe Gros; Prem Ponka
Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms.
Experimental hematology 2008;36(10):1227-35.
2008: Shan Soe-Lin; Alex Sheftel; Brandi Wasyluk; Prem Ponka
Nramp1 equips macrophages for efficient iron recycling.
Experimental hematology 2008;36(8):929-37.
2008: Megan Whitnall; Robert Sutak; Xiangcong Xu; Erika M Becker; Marc R Mikhael; Prem Ponka; Yohan Suryo Rahmanto; Des R Richardson
The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9757-62.
2008: Natasha Szuber; Joan L Buss; Shan Soe-Lin; Hady Felfly; Marie Trudel; Prem Ponka
Alternative treatment paradigm for thalassemia using iron chelators.
Experimental hematology 2008;36(7):773-85.
2007: Alex Sheftel; An-Sheng Zhang; Claire Brown; orian shirihai; Prem Ponka
Direct interorganellar transfer of iron from endosome to mitochondrion.
Blood 2007;110(1):125-32.
2007: Martin Sterba; Olga Popelová; Tomás Simůnek; Yvona Mazurová; Anna Potácová; Michaela Adamcová; Ivana Guncová; Helena Kaiserová; Vladimír Palicka; Prem Ponka; Vladimír Gersl
Iron chelation-afforded cardioprotection against chronic anthracycline cardiotoxicity: a study of salicylaldehyde isonicotinoyl hydrazone (SIH).
Toxicology 2007;235(3):150-66.
2007: Alex Sheftel; Sangwon Kim; Prem Ponka
Non-heme induction of heme oxygenase-1 does not alter cellular iron metabolism.
The Journal of biological chemistry 2007;282(14):10480-6.
2007: Anna Potácová; Michaela Adamcová; H Cajnáková; L Hrbatová; Martin Sterba; Olga Popelová; T Simůnek; Prem Ponka; Vladimír Gersl
Evaluation of ECG time intervals in a rabbit model of anthracycline-induced cardiomyopathy: a useful tool for assessment of cardioprotective agents.
Physiological research / Academia Scientiarum Bohemoslovaca 2007;56(2):251-4.
2006: Martin Sterba; Olga Popelová; Tomas Simunek; Yvona Mazurová; Anna Potácová; Michaela Adamcová; Helena Kaiserová; Prem Ponka; Vladimír Gersl
Cardioprotective effects of a novel iron chelator, pyridoxal 2-chlorobenzoyl hydrazone, in the rabbit model of daunorubicin-induced cardiotoxicity.
The Journal of pharmacology and experimental therapeutics 2006;319(3):1336-47.
2006: Megan Whitnall; Jonathan Howard; Prem Ponka; Des R Richardson
A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14901-6.
2006: Guangjun Nie; Guohua Chen; Alex Sheftel; Kostas Pantopoulos; Prem Ponka
In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin.
Blood 2006;108(7):2428-34.
2006: Donghoon Yoon; Yves D Pastore; Vladimir Divoky; Enli Liu; Agnieszka E Mlodnicka; Karin Rainey; Prem Ponka; Gregg L Semenza; Armin Schumacher; Josef T Prchal
Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development.
The Journal of biological chemistry 2006;281(35):25703-11.
2006: Marc Mikhael; Sangwon Kim; Matthias Schranzhofer; Shan Soe-Lin; Shan S Lin; Alex Sheftel; Ernst W Mullner; Prem Ponka
Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide.
The FEBS journal 2006;273(16):3828-36.
2006: Petra Kovaríková; Jirí Klimes; Martin Sterba; Olga Popelová; Vladimír Gersl; Prem Ponka
HPLC determination of a novel aroylhydrazone iron chelator (o-108) in rabbit plasma and its application to a pilot pharmacokinetic study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;838(2):107-12.
2006: Ralph N Watts; Clare Hawkins; Prem Ponka; Des R Richardson
Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7670-5.
2006: An-Sheng Zhang; Alex Sheftel; Prem Ponka
The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling.
Experimental hematology 2006;34(5):593-8.
2005: C Mouralian; Joan L Buss; B Stranix; J Chin; Prem Ponka
Mobilization of iron from cells by hydroxyquinoline-based chelators.
Biochemical pharmacology 2005;71(1-2):214-22.
2005: Monika Priwitzerova; Guangjun Nie; Alex Sheftel; Dagmar Pospisilova; Vladimir Divoky; Prem Ponka
Functional consequences of the human DMT1 (SLC11A2) mutation on protein expression and iron uptake.
Blood 2005;106(12):3985-7.
2005: Martin Sterba; T Simůnek; Yvona Mazurová; Michaela Adamcová; Olga Popelová; J Kaplanova; Prem Ponka; Vladimír Gersl
Safety and tolerability of repeated administration of pyridoxal 2-chlorobenzoyl hydrazone in rabbits.
Human & experimental toxicology 2005;24(11):581-9.
2005: Petra Kovaríková; Jirí Klimes; Martin Stĕrba; Olga Popelová; Milan Mokrý; Vladimír Gersl; Prem Ponka
Development of high-performance liquid chromatographic determination of salicylaldehyde isonicotinoyl hydrazone in rabbit plasma and application of this method to an in vivo study.
Journal of separation science 2005;28(12):1300-6.
2005: Tomás Simůnek; Christa Boer; R Arthur Bouwman; Ronald Vlasblom; Amanda M G Versteilen; Martin Sterba; Vladimír Gersl; Radomír Hrdina; Prem Ponka; Jaap J de Lange; Walter J Paulus; René J P Musters
SIH--a novel lipophilic iron chelator--protects H9c2 cardiomyoblasts from oxidative stress-induced mitochondrial injury and cell death.
Journal of molecular and cellular cardiology 2005;39(2):345-54.
2005: Carine Fillebeen; Ana María Rivas-Estilla; Martin Bisaillon; Prem Ponka; Martina U Muckenthaler; Matthias W Hentze; Antonis E Koromilas; Kostas Pantopoulos
Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus.
The Journal of biological chemistry 2005;280(10):9049-57.
2005: T Simůnek; Ivona Klimtová; Jana Kaplanová; Martin Sterba; Yvona Mazurová; Michaela Adamcová; Radomír Hrdina; Vladimír Gersl; Prem Ponka
Study of daunorubicin cardiotoxicity prevention with pyridoxal isonicotinoyl hydrazone in rabbits.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;51(3):223-31.
2005: Ian Napier; Prem Ponka; Des R Richardson
Iron trafficking in the mitochondrion: novel pathways revealed by disease.
Blood 2005;105(5):1867-74.
2005: Guangjun Nie; Alex Sheftel; Sangwon Kim; Prem Ponka
Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis.
Blood 2005;105(5):2161-7.
2005: Martha P Mims; Yongli Guan; Dagmar Pospisilova; Monika Priwitzerova; Karel Indrak; Prem Ponka; Vladimir Divoky; Josef T Prchal
Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload.
Blood 2005;105(3):1337-42.
2005: An-Sheng Zhang; Alex Sheftel; Prem Ponka
Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria.
Blood 2005;105(1):368-75.
2004: William E Crowe; Lilia M Maglova; Prem Ponka; John Russell
Human cytomegalovirus-induced host cell enlargement is iron dependent.
American journal of physiology. Cell physiology 2004;287(4):C1023-30.
2004: Monika Priwitzerova; Dagmar Pospisilova; Josef T Prchal; Karel Indrak; Alice Hlobilkova; Vladimir Mihal; Prem Ponka; Vladimir Divoky
Severe hypochromic microcytic anemia caused by a congenital defect of the iron transport pathway in erythroid cells.
Blood 2004;103(10):3991-2.
2004: Prem Ponka
Hereditary causes of disturbed iron homeostasis in the central nervous system.
Annals of the New York Academy of Sciences 2004;1012():267-81.
2004: Mark J Koury; Prem Ponka
New insights into erythropoiesis: the roles of folate, vitamin B12, and iron.
Annual review of nutrition 2004;24():105-31.
2004: Joan L Buss; Jiri Neuzil; Prem Ponka
Oxidative stress mediates toxicity of pyridoxal isonicotinoyl hydrazone analogs.
Archives of biochemistry and biophysics 2004;421(1):1-9.
2004: Sangwon Kim; Simon S Wing; Prem Ponka
S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathway.
Molecular and cellular biology 2004;24(1):330-7.
2003: Gabriela Link; Prem Ponka; Abraham M Konijn; William Breuer; Ioav Cabantchik; Chaim Hershko
Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells.
Blood 2003;101(10):4172-9.
2003: Sangwon Kim; Prem Ponka
Role of nitric oxide in cellular iron metabolism.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2003;16(1):125-35.
2003: Joan L Buss; Emmanuele Arduini; Kyle C Shephard; Prem Ponka
Lipophilicity of analogs of pyridoxal isonicotinoyl hydrazone (PIH) determines the efflux of iron complexes and toxicity in K562 cells.
Biochemical pharmacology 2003;65(3):349-60.
2003: Ralph N Watts; Prem Ponka; Des R Richardson
Effects of nitrogen monoxide and carbon monoxide on molecular and cellular iron metabolism: mirror-image effector molecules that target iron.
The Biochemical journal 2003;369(Pt 3):429-40.
2003: Joan L Buss; Prem Ponka
Hydrolysis of pyridoxal isonicotinoyl hydrazone and its analogs.
Biochimica et biophysica acta 2003;1619(2):177-86.
2003: Joan L Buss; Jiri Neuzil; Nina Gellert; Christian Weber; Prem Ponka
Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties.
Biochemical pharmacology 2003;65(2):161-72.
2003: Michaela Adamcová; Martin Sterba; Ivona Klimtová; Tomás Simůnek; Radomír Hrdina; Vladimír Gersl; Prem Ponka
Cardiac troponins following repeated administration of an iron chelator--salicylaldehyde isonicotinoyl hydrazone (SIH)--in rabbits.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové 2003;46(4):171-4.
2003: Ivona Klimtová; Tomás Simůnek; Yvona Mazurová; Jana Kaplanová; Martin Sterba; Radomír Hrdina; Vladimír Gersl; Michaela Adamcová; Prem Ponka
A study of potential toxic effects after repeated 10-week administration of a new iron chelator--salicylaldehyde isonicotinoyl hydrazone (SIH) to rabbits.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové 2003;46(4):163-70.
2002: Joan L Buss; Emmanuele Arduini; Prem Ponka
Mobilization of intracellular iron by analogs of pyridoxal isonicotinoyl hydrazone (PIH) is determined by the membrane permeability of the iron-chelator complexes.
Biochemical pharmacology 2002;64(12):1689-701.
2002: Sangwon Kim; Prem Ponka
Nitric oxide-mediated modulation of iron regulatory proteins: implication for cellular iron homeostasis.
Blood cells, molecules & diseases 2002;29(3):400-10.
2002: Jian Wang; Joan L Buss; Guohua Chen; Prem Ponka; Kostas Pantopoulos
The prolyl 4-hydroxylase inhibitor ethyl-3,4-dihydroxybenzoate generates effective iron deficiency in cultured cells.
FEBS letters 2002;529(2-3):309-12.
2002: Prem Ponka
Rare causes of hereditary iron overload.
Seminars in hematology 2002;39(4):249-62.
2002: Sangwon Kim; Prem Ponka
Nitrogen monoxide-mediated control of ferritin synthesis: implications for macrophage iron homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12214-9.
2002: Joan L Buss; Jiri Neuzil; Prem Ponka
The role of oxidative stress in the toxicity of pyridoxal isonicotinoyl hydrazone (PIH) analogues.
Biochemical Society transactions 2002;30(4):755-7.
2002: Prem Ponka; Alex Sheftel; An-Sheng Zhang
Iron targeting to mitochondria in erythroid cells.
Biochemical Society transactions 2002;30(4):735-8.
2002: Lioba Lobmayr; Thomas Sauer; Iris Killisch; Matthias Schranzhofer; Robert B Wilson; Prem Ponka; Hartmut Beug; Ernst W Müllner
Transferrin receptor hyperexpression in primary erythroblasts is lost on transformation by avian erythroblastosis virus.
Blood 2002;100(1):289-98.
2002: Erika M Becker; Judith Greer; Prem Ponka; Des R Richardson
Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization.
Blood 2002;99(10):3813-22.
2002: Joan L Buss; Marcelo Hermes-Lima; Prem Ponka
Pyridoxal isonicotinoyl hydrazone and its analogues.
Advances in experimental medicine and biology 2002;509():205-29.
2002: Michaela Adamcová; Jarmila Machácková; Vladimír Gersl; V Pelouch; T Simůnek; Ivona Klimtová; Radomír Hrdina; Prem Ponka
Cardiac troponin T following repeated administration of pyridoxal isonicotinoyl hydrazone in rabbits.
Physiological research / Academia Scientiarum Bohemoslovaca 2002;51(5):443-8.
2002: Prem Ponka; Sangwon Kim
S-nitrosothiols control breathing and oxygen homeostasis.
Redox report : communications in free radical research 2002;7(1):5-7.
2001: François Canonne-Hergaux; An-Sheng Zhang; Prem Ponka; Philippe Gros
Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice.
Blood 2001;98(13):3823-30.
2001: D R Richardson; C Mouralian; Prem Ponka; E Becker
Development of potential iron chelators for the treatment of Friedreich's ataxia: ligands that mobilize mitochondrial iron.
Biochimica et biophysica acta 2001;1536(2-3):133-40.
2000: Marcelo Hermes-Lima; Prem Ponka; HM Schulman
The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) and its analogues prevent damage to 2-deoxyribose mediated by ferric iron plus ascorbate.
Biochimica et biophysica acta 2000;1523(2-3):154-60.
2000: Frederick Nestel; R N Greene; K Kichian; Prem Ponka; Wayne S Lapp
Activation of macrophage cytostatic effector mechanisms during acute graft-versus-host disease: release of intracellular iron and nitric oxide-mediated cytostasis.
Blood 2000;96(5):1836-43.
2000: Chun-Nam Lok; Prem Ponka
Identification of an erythroid active element in the transferrin receptor gene.
The Journal of biological chemistry 2000;275(31):24185-90.
2000: Sangwon Kim; Prem Ponka
Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2.
The Journal of biological chemistry 2000;275(9):6220-6.
1999: Sangwon Kim; Prem Ponka
Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2.
The Journal of biological chemistry 1999;274(46):33035-42.
1999: Prem Ponka; Chun-Nam Lok
The transferrin receptor: role in health and disease.
The international journal of biochemistry & cell biology 1999;31(10):1111-37.
1999: Prem Ponka
Cell biology of heme.
The American journal of the medical sciences 1999;318(4):241-56.
1999: Chun-Nam Lok; Prem Ponka
Identification of a hypoxia response element in the transferrin receptor gene.
The Journal of biological chemistry 1999;274(34):24147-52.
1999: François Canonne-Hergaux; Samantha Gruenheid; Prem Ponka; Philippe Gros
Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron.
Blood 1999;93(12):4406-17.
1999: Prem Ponka
Cellular iron metabolism.
Kidney international. Supplement 1999;69():S2-11.
1999: Marcelo Hermes-Lima; Natacha C F Santos; J Yan; M Andrews; HM Schulman; Prem Ponka
EPR spin trapping and 2-deoxyribose degradation studies of the effect of pyridoxal isonicotinoyl hydrazone (PIH) on *OH formation by the Fenton reaction.
Biochimica et biophysica acta 1999;1426(3):475-82.
1999: Emanuel Necas; Karel Sulc; J H Zivný; Viktor Sykora; Prem Ponka
Red blood cell degradation products modify responsiveness of erythropoietin gene to hypoxia.
Advances in experimental medicine and biology 1999;471():427-37.
1998: Marcelo Hermes-Lima; E Nagy; Prem Ponka; HM Schulman
The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) protects plasmid pUC-18 DNA against *OH-mediated strand breaks.
Free radical biology & medicine 1998;25(8):875-80.
1998: Emanuel Necas; Prem Ponka
Ureter obliteration transiently depresses erythropoietin production.
European journal of clinical investigation 1998;28(11):918-23.
1998: Prem Ponka; C Beaumont; D R Richardson
Function and regulation of transferrin and ferritin.
Seminars in hematology 1998;35(1):35-54.
1997: Jacob Golenser; Abraham J Domb; D Teomim; A Tsafack; O Nisim; Prem Ponka; W Eling; Ioav Cabantchik
The treatment of animal models of malaria with iron chelators by use of a novel polymeric device for slow drug release.
The Journal of pharmacology and experimental therapeutics 1997;281(3):1127-35.
1997: D R Richardson; Prem Ponka
The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells.
Biochimica et biophysica acta 1997;1331(1):1-40.
1997: Prem Ponka
Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells.
Blood 1997;89(1):1-25.
1997: M Bhattacharya; Prem Ponka; Pierre Hardy; N Hanna; Daya R Varma; Pierre Lachapelle; Sylvain Chemtob
Prevention of postasphyxia electroretinal dysfunction with a pyridoxal hydrazone.
Free radical biology & medicine 1997;22(1-2):11-6.
1996: D R Richardson; Prem Ponka; D Vyoral
Distribution of iron in reticulocytes after inhibition of heme synthesis with succinylacetone: examination of the intermediates involved in iron metabolism.
Blood 1996;87(8):3477-88.
1995: D R Richardson; E H Tran; Prem Ponka
The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents.
Blood 1995;86(11):4295-306.
1995: D R Richardson; Prem Ponka
Identification of a mechanism of iron uptake by cells which is stimulated by hydroxyl radicals generated via the iron-catalysed Haber-Weiss reaction.
Biochimica et biophysica acta 1995;1269(2):105-14.
1995: D R Richardson; V Neumannova; E Nagy; Prem Ponka
The effect of redox-related species of nitrogen monoxide on transferrin and iron uptake and cellular proliferation of erythroleukemia (K562) cells.
Blood 1995;86(8):3211-9.
1995: D R Richardson; V Neumannova; Prem Ponka
Nitrogen monoxide decreases iron uptake from transferrin but does not mobilise iron from prelabelled neoplastic cells.
Biochimica et biophysica acta 1995;1266(3):250-60.
1994: D R Richardson; Prem Ponka
The iron metabolism of the human neuroblastoma cell: lack of relationship between the efficacy of iron chelation and the inhibition of DNA synthesis.
The Journal of laboratory and clinical medicine 1994;124(5):660-71.
1994: Marcelo Hermes-Lima; E M Wang; H M Schulman; Kenneth Storey; Prem Ponka
Deoxyribose degradation catalyzed by Fe(III)-EDTA: kinetic aspects and potential usefulness for submicromolar iron measurements.
Molecular and cellular biochemistry 1994;137(1):65-73.
1994: Prem Ponka; D R Richardson; J T Edward; F L Chubb
Iron chelators of the pyridoxal isonicotinoyl hydrazone class. Relationship of the lipophilicity of the apochelator to its ability to mobilise iron from reticulocytes in vitro.
Canadian journal of physiology and pharmacology 1994;72(6):659-66.
1994: R Y Chan; Christian Seiser; H M Schulman; Lukas C Kühn; Prem Ponka
Regulation of transferrin receptor mRNA expression. Distinct regulatory features in erythroid cells.
European journal of biochemistry / FEBS 1994;220(3):683-92.
1994: D Richardson; Prem Ponka; E Baker
The effect of the iron(III) chelator, desferrioxamine, on iron and transferrin uptake by the human malignant melanoma cell.
Cancer research 1994;54(3):685-9.
1994: Prem Ponka; H M Schulman
Distinct features of iron metabolism in erythroid cells: implications for heme synthesis regulation.
Advances in experimental medicine and biology 1994;356():173-87.
1993: R Y Chan; H M Schulman; Prem Ponka
Expression of ferrochelatase mRNA in erythroid and non-erythroid cells.
The Biochemical journal 1993;292 ( Pt 2)():343-9.
1993: Prem Ponka; H M Schulman
Regulation of heme biosynthesis: distinct regulatory features in erythroid cells.
Stem cells (Dayton, Ohio) 1993;11 Suppl 1():24-35.
1992: R Y Chan; Prem Ponka; H M Schulman
Transferrin-receptor-independent but iron-dependent proliferation of variant Chinese hamster ovary cells.
Experimental cell research 1992;202(2):326-36.
1989: H M Schulman; Prem Ponka; A Wilczynska; Y Gauthier; Gopalan Shyamala
Transferrin receptor and ferritin levels during murine mammary gland development.
Biochimica et biophysica acta 1989;1010(1):1-6.
1988: Prem Ponka; D Richardson; E Baker; H M Schulman; J T Edward
Effect of pyridoxal isonicotinoyl hydrazone and other hydrazones on iron release from macrophages, reticulocytes and hepatocytes.
Biochimica et biophysica acta 1988;967(1):122-9.
1988: J Laskey; I Webb; H M Schulman; Prem Ponka
Evidence that transferrin supports cell proliferation by supplying iron for DNA synthesis.
Experimental cell research 1988;176(1):87-95.
1988: Prem Ponka; H M Schulman; J Martinez-Medellin
Haem inhibits iron uptake subsequent to endocytosis of transferrin in reticulocytes.
The Biochemical journal 1988;251(1):105-9.
1986: J D Laskey; Prem Ponka; H M Schulman
Control of heme synthesis during Friend cell differentiation: role of iron and transferrin.
Journal of cellular physiology 1986;129(2):185-92.
1985: Prem Ponka; H M Schulman
Acquisition of iron from transferrin regulates reticulocyte heme synthesis.
The Journal of biological chemistry 1985;260(27):14717-21.
1985: Prem Ponka; H M Schulman
Regulation of heme synthesis in erythroid cells: hemin inhibits transferrin iron utilization but not protoporphyrin synthesis.
Blood 1985;65(4):850-7.
1984: Prem Ponka; R W Grady; A Wilczynska; H M Schulman
The effect of various chelating agents on the mobilization of iron from reticulocytes in the presence and absence of pyridoxal isonicotinoyl hydrazone.
Biochimica et biophysica acta 1984;802(3):477-89.
1984: A Wilczynska; Prem Ponka; H M Schulman
Transferrin receptors and iron utilization in DMSO-inducible and -uninducible Friend erythroleukemia cells.
Experimental cell research 1984;154(2):561-6.
1982: Prem Ponka; H M Schulman; A Wilczynska
Ferric pyridoxal isonicotinoyl hydrazone can provide iron for heme synthesis in reticulocytes.
Biochimica et biophysica acta 1982;718(2):151-6.
1982: Prem Ponka; A Wilczynska; H M Schulman
Iron utilization in rabbit reticulocytes. A study using succinylacetone as an inhibitor or heme synthesis.
Biochimica et biophysica acta 1982;720(1):96-105.
1981: H M Schulman; Prem Ponka
The stimulation of globin synthesis by cobalt in reticulocytes with inhibited heme synthesis.
Biochimica et biophysica acta 1981;654(1):166-8.
1981: H M Schulman; A Wilczynska; Prem Ponka
Transferrin and iron uptake by human lymphoblastoid and K-562 cells.
Biochemical and biophysical research communications 1981;100(4):1523-30.