Prem Ponka

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Huang Michael Li-Hsuan; Becker Erika M; Whitnall Megan; Rahmanto Yohan Suryo; Ponka Prem; Richardson Des R
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant.
Peslova Gabriela; Petrak Jiri; Kuzelova Katerina; Hrdy Ivan; Halada Petr; Kuchel Philip W; Soe-Lin Shan; Ponka Prem; Sutak Robert; Becker Erika; Huang Michael Li-Hsuan; Rahmanto Yohan Suryo; Richardson Des R; Vyoral Daniel
Hepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in blood.
Soe-Lin Shan; Apte Sameer S; Andriopoulos Billy; Andrews Marc C; Schranzhofer Matthias; Kahawita Tanya; Garcia-Santos Daniel; Ponka Prem
Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo.

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2009: Huang Michael Li-Hsuan; Becker Erika M; Whitnall Megan; Rahmanto Yohan Suryo; Ponka Prem; Richardson Des R
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16381-6.
2009: Peslova Gabriela; Petrak Jiri; Kuzelova Katerina; Hrdy Ivan; Halada Petr; Kuchel Philip W; Soe-Lin Shan; Ponka Prem; Sutak Robert; Becker Erika; Huang Michael Li-Hsuan; Rahmanto Yohan Suryo; Richardson Des R; Vyoral Daniel
Hepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in blood.
Blood 2009;113(24):6225-36.
2009: Soe-Lin Shan; Apte Sameer S; Andriopoulos Billy; Andrews Marc C; Schranzhofer Matthias; Kahawita Tanya; Garcia-Santos Daniel; Ponka Prem
Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5960-5.
2009: Jeong Suh Young; Rathore Khizr I; Schulz Katrin; Ponka Prem; Arosio Paolo; David Samuel
Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(3):610-9.
2009: Sheftel Alex D; Richardson Des R; Prchal Josef; Ponka Prem
Mitochondrial iron metabolism and sideroblastic anemia.
Acta haematologica 2009;122(2-3):120-33.
2008: Rathore Khizr I; Kerr Bradley J; Redensek Adriana; López-Vales Rubèn; Jeong Suh Young; Ponka Prem; David Samuel
Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(48):12736-47.
2008: Zhang An-Sheng; Canonne-Hergaux Francois; Gruenheid Samantha; Gros Philippe; Ponka Prem
Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms.
Experimental hematology 2008;36(10):1227-35.
2008: Soe-Lin Shan; Sheftel Alex D; Wasyluk Brandi; Ponka Prem
Nramp1 equips macrophages for efficient iron recycling.
Experimental hematology 2008;36(8):929-37.
2008: Whitnall Megan; Rahmanto Yohan Suryo; Sutak Robert; Xu Xiangcong; Becker Erika M; Mikhael Marc R; Ponka Prem; Richardson Des R
The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9757-62.
2008: Szuber Natasha; Buss Joan L; Soe-Lin Shan; Felfly Hady; Trudel Marie; Ponka Prem
Alternative treatment paradigm for thalassemia using iron chelators.
Experimental hematology 2008;36(7):773-85.
2007: Sheftel Alex D; Zhang An-Sheng; Brown Claire; Shirihai Orian S; Ponka Prem
Direct interorganellar transfer of iron from endosome to mitochondrion.
Blood 2007;110(1):125-32.
2007: Sterba Martin; Popelová Olga; Simunek Tomás; Mazurová Yvona; Potácová Anna; Adamcová Michaela; Guncová Ivana; Kaiserová Helena; Palicka Vladimír; Ponka Premysl; Gersl Vladimír
Iron chelation-afforded cardioprotection against chronic anthracycline cardiotoxicity: a study of salicylaldehyde isonicotinoyl hydrazone (SIH).
Toxicology 2007;235(3):150-66.
2007: Sheftel Alex D; Kim Sangwon F; Ponka Prem
Non-heme induction of heme oxygenase-1 does not alter cellular iron metabolism.
The Journal of biological chemistry 2007;282(14):10480-6.
2007: Potácová A; Adamcová M; Cajnáková H; Hrbatová L; Sterba M; Popelová O; Simunek T; Ponka P; Gersl V
Evaluation of ECG time intervals in a rabbit model of anthracycline-induced cardiomyopathy: a useful tool for assessment of cardioprotective agents.
Physiological research / Academia Scientiarum Bohemoslovaca 2007;56(2):251-4.
2006: Sterba Martin; Popelová Olga; Simunek Tomás; Mazurová Yvona; Potácová Anna; Adamcová Michaela; Kaiserová Helena; Ponka Premysl; Gersl Vladimír
Cardioprotective effects of a novel iron chelator, pyridoxal 2-chlorobenzoyl hydrazone, in the rabbit model of daunorubicin-induced cardiotoxicity.
The Journal of pharmacology and experimental therapeutics 2006;319(3):1336-47.
2006: Whitnall Megan; Howard Jonathan; Ponka Prem; Richardson Des R
A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14901-6.
2006: Nie Guangjun; Chen Guohua; Sheftel Alex D; Pantopoulos Kostas; Ponka Prem
In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin.
Blood 2006;108(7):2428-34.
2006: Yoon Donghoon; Pastore Yves D; Divoky Vladimir; Liu Enli; Mlodnicka Agnieszka E; Rainey Karin; Ponka Premysl; Semenza Gregg L; Schumacher Armin; Prchal Josef T
Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development.
The Journal of biological chemistry 2006;281(35):25703-11.
2006: Mikhael Marc; Kim Sangwon F; Schranzhofer Matthias; Soe-Lin Shan; Sheftel Alex D; Mullner Ernst W; Ponka Prem
Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide.
The FEBS journal 2006;273(16):3828-36.
2006: Kovaríková Petra; Klimes Jirí; Sterba Martin; Popelová Olga; Gersl Vladimír; Ponka Premysl
HPLC determination of a novel aroylhydrazone iron chelator (o-108) in rabbit plasma and its application to a pilot pharmacokinetic study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;838(2):107-12.
2006: Watts Ralph N; Hawkins Clare; Ponka Prem; Richardson Des R
Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7670-5.
2006: Zhang An-Sheng; Sheftel Alex D; Ponka Prem
The anemia of "haemoglobin-deficit" (hbd/hbd) mice is caused by a defect in transferrin cycling.
Experimental hematology 2006;34(5):593-8.
2005: Mouralian C; Buss J L; Stranix B; Chin J; Ponka P
Mobilization of iron from cells by hydroxyquinoline-based chelators.
Biochemical pharmacology 2005;71(1-2):214-22.
2005: Priwitzerova Monika; Nie Guangjun; Sheftel Alex D; Pospisilova Dagmar; Divoky Vladimir; Ponka Prem
Functional consequences of the human DMT1 (SLC11A2) mutation on protein expression and iron uptake.
Blood 2005;106(12):3985-7.
2005: Sterba M; Simunek T; Mazurová Y; Adamcová M; Popelová O; Kaplanova J; Ponka P; Gersl V
Safety and tolerability of repeated administration of pyridoxal 2-chlorobenzoyl hydrazone in rabbits.
Human & experimental toxicology 2005;24(11):581-9.
2005: Kovaríková Petra; Klimes Jirí; Sterba Martin; Popelová Olga; Mokrý Milan; Gersl Vladimír; Ponka Premysl
Development of high-performance liquid chromatographic determination of salicylaldehyde isonicotinoyl hydrazone in rabbit plasma and application of this method to an in vivo study.
Journal of separation science 2005;28(12):1300-6.
2005: Simunek Tomás; Boer Christa; Bouwman R Arthur; Vlasblom Ronald; Versteilen Amanda M G; Sterba Martin; Gersl Vladimír; Hrdina Radomír; Ponka Premysl; de Lange Jaap J; Paulus Walter J; Musters René J P
SIH--a novel lipophilic iron chelator--protects H9c2 cardiomyoblasts from oxidative stress-induced mitochondrial injury and cell death.
Journal of molecular and cellular cardiology 2005;39(2):345-54.
2005: Simunek T; Klimtová I; Kaplanová J; Sterba M; Mazurová Y; Adamcová M; Hrdina R; Gersl V; Ponka P
Study of daunorubicin cardiotoxicity prevention with pyridoxal isonicotinoyl hydrazone in rabbits.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;51(3):223-31.
2005: Fillebeen Carine; Rivas-Estilla Ana Maria; Bisaillon Martin; Ponka Prem; Muckenthaler Martina; Hentze Matthias W; Koromilas Antonis E; Pantopoulos Kostas
Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus.
The Journal of biological chemistry 2005;280(10):9049-57.
2005: Napier Ian; Ponka Prem; Richardson Des R
Iron trafficking in the mitochondrion: novel pathways revealed by disease.
Blood 2005;105(5):1867-74.
2005: Nie Guangjun; Sheftel Alex D; Kim Sangwon F; Ponka Prem
Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis.
Blood 2005;105(5):2161-7.
2005: Mims Martha P; Guan Yongli; Pospisilova Dagmar; Priwitzerova Monika; Indrak Karel; Ponka Prem; Divoky Vladimir; Prchal Josef T
Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload.
Blood 2005;105(3):1337-42.
2005: Zhang An-Sheng; Sheftel Alex D; Ponka Prem
Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria.
Blood 2005;105(1):368-75.
2004: Crowe William E; Maglova Lilia M; Ponka Prem; Russell John M
Human cytomegalovirus-induced host cell enlargement is iron dependent.
American journal of physiology. Cell physiology 2004;287(4):C1023-30.
2004: Priwitzerova Monika; Pospisilova Dagmar; Prchal Josef T; Indrak Karel; Hlobilkova Alice; Mihal Vladimir; Ponka Prem; Divoky Vladimir
Severe hypochromic microcytic anemia caused by a congenital defect of the iron transport pathway in erythroid cells.
Blood 2004;103(10):3991-2.
2004: Ponka Prem
Hereditary causes of disturbed iron homeostasis in the central nervous system.
Annals of the New York Academy of Sciences 2004;1012():267-81.
2004: Buss Joan L; Neuzil Jiri; Ponka Prem
Oxidative stress mediates toxicity of pyridoxal isonicotinoyl hydrazone analogs.
Archives of biochemistry and biophysics 2004;421(1):1-9.
2004: Kim Sangwon; Wing Simon S; Ponka Prem
S-nitrosylation of IRP2 regulates its stability via the ubiquitin-proteasome pathway.
Molecular and cellular biology 2004;24(1):330-7.
2004: Koury Mark J; Ponka Prem
New insights into erythropoiesis: the roles of folate, vitamin B12, and iron.
Annual review of nutrition 2004;24():105-31.
2003: Link Gabriela; Ponka Prem; Konijn Abraham M; Breuer William; Cabantchik Z Ioav; Hershko Chaim
Effects of combined chelation treatment with pyridoxal isonicotinoyl hydrazone analogs and deferoxamine in hypertransfused rats and in iron-loaded rat heart cells.
Blood 2003;101(10):4172-9.
2003: Kim Sangwon; Ponka Prem
Role of nitric oxide in cellular iron metabolism.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2003;16(1):125-35.
2003: Buss Joan L; Arduini Emmanuele; Shephard Kyle C; Ponka Prem
Lipophilicity of analogs of pyridoxal isonicotinoyl hydrazone (PIH) determines the efflux of iron complexes and toxicity in K562 cells.
Biochemical pharmacology 2003;65(3):349-60.
2003: Watts Ralph N; Ponka Prem; Richardson Des R
Effects of nitrogen monoxide and carbon monoxide on molecular and cellular iron metabolism: mirror-image effector molecules that target iron.
The Biochemical journal 2003;369(Pt 3):429-40.
2003: Buss Joan L; Ponka Prem
Hydrolysis of pyridoxal isonicotinoyl hydrazone and its analogs.
Biochimica et biophysica acta 2003;1619(2):177-86.
2003: Buss Joan L; Neuzil Jiri; Gellert Nina; Weber Christian; Ponka Prem
Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties.
Biochemical pharmacology 2003;65(2):161-72.
2003: Adamcová Michaela; Sterba Martin; Klimtová Ivona; Simunek Tomás; Hrdina Radomír; Gersl Vladimír; Ponka Premysl
Cardiac troponins following repeated administration of an iron chelator--salicylaldehyde isonicotinoyl hydrazone (SIH)--in rabbits.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové 2003;46(4):171-4.
2003: Klimtová Ivona; Simunek Tomás; Mazurová Yvona; Kaplanová Jana; Sterba Martin; Hrdina Radomír; Gersl Vladimír; Adamcová Michaela; Ponka Premysl
A study of potential toxic effects after repeated 10-week administration of a new iron chelator--salicylaldehyde isonicotinoyl hydrazone (SIH) to rabbits.
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové 2003;46(4):163-70.
2002: Buss Joan L; Arduini Emmanuele; Ponka Prem
Mobilization of intracellular iron by analogs of pyridoxal isonicotinoyl hydrazone (PIH) is determined by the membrane permeability of the iron-chelator complexes.
Biochemical pharmacology 2002;64(12):1689-701.
2002: Kim Sangwon; Ponka Prem
Nitric oxide-mediated modulation of iron regulatory proteins: implication for cellular iron homeostasis.
Blood cells, molecules & diseases 2002;29(3):400-10.
2002: Ponka Prem
Rare causes of hereditary iron overload.
Seminars in hematology 2002;39(4):249-62.
2002: Wang Jian; Buss Joan L; Chen Guohua; Ponka Prem; Pantopoulos Kostas
The prolyl 4-hydroxylase inhibitor ethyl-3,4-dihydroxybenzoate generates effective iron deficiency in cultured cells.
FEBS letters 2002;529(2-3):309-12.
2002: Kim Sangwon; Ponka Prem
Nitrogen monoxide-mediated control of ferritin synthesis: implications for macrophage iron homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12214-9.
2002: Buss J L; Neuzil J; Ponka P
The role of oxidative stress in the toxicity of pyridoxal isonicotinoyl hydrazone (PIH) analogues.
Biochemical Society transactions 2002;30(4):755-7.
2002: Ponka P; Sheftel A D; Zhang A-S
Iron targeting to mitochondria in erythroid cells.
Biochemical Society transactions 2002;30(4):735-8.
2002: Lobmayr Lioba; Sauer Thomas; Killisch Iris; Schranzhofer Matthias; Wilson Robert B; Ponka Prem; Beug Hartmut; Müllner Ernst W
Transferrin receptor hyperexpression in primary erythroblasts is lost on transformation by avian erythroblastosis virus.
Blood 2002;100(1):289-98.
2002: Becker Erika M; Greer Judith M; Ponka Prem; Richardson Des R
Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization.
Blood 2002;99(10):3813-22.
2002: Buss Joan L; Hermes-Lima Marcelo; Ponka Prem
Pyridoxal isonicotinoyl hydrazone and its analogues.
Advances in experimental medicine and biology 2002;509():205-29.
2002: Adamcová M; Machácková J; Gersl V; Pelouch V; Simunek T; Klimtová I; Hrdina R; Ponka P
Cardiac troponin T following repeated administration of pyridoxal isonicotinoyl hydrazone in rabbits.
Physiological research / Academia Scientiarum Bohemoslovaca 2002;51(5):443-8.
2002: Ponka Prem; Kim Sangwon
S-nitrosothiols control breathing and oxygen homeostasis.
Redox report : communications in free radical research 2002;7(1):5-7.
2001: Canonne-Hergaux F; Zhang A S; Ponka P; Gros P
Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice.
Blood 2001;98(13):3823-30.
2001: Richardson D R; Mouralian C; Ponka P; Becker E
Development of potential iron chelators for the treatment of Friedreich's ataxia: ligands that mobilize mitochondrial iron.
Biochimica et biophysica acta 2001;1536(2-3):133-40.
2000: Hermes-Lima M; Ponka P; Schulman H M
The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) and its analogues prevent damage to 2-deoxyribose mediated by ferric iron plus ascorbate.
Biochimica et biophysica acta 2000;1523(2-3):154-60.
2000: Nestel F P; Greene R N; Kichian K; Ponka P; Lapp W S
Activation of macrophage cytostatic effector mechanisms during acute graft-versus-host disease: release of intracellular iron and nitric oxide-mediated cytostasis.
Blood 2000;96(5):1836-43.
2000: Lok C N; Ponka P
Identification of an erythroid active element in the transferrin receptor gene.
The Journal of biological chemistry 2000;275(31):24185-90.
2000: Kim S; Ponka P
Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2.
The Journal of biological chemistry 2000;275(9):6220-6.
1999: Kim S; Ponka P
Control of transferrin receptor expression via nitric oxide-mediated modulation of iron-regulatory protein 2.
The Journal of biological chemistry 1999;274(46):33035-42.
1999: Ponka P; Lok C N
The transferrin receptor: role in health and disease.
The international journal of biochemistry & cell biology 1999;31(10):1111-37.
1999: Ponka P
Cell biology of heme.
The American journal of the medical sciences 1999;318(4):241-56.
1999: Lok C N; Ponka P
Identification of a hypoxia response element in the transferrin receptor gene.
The Journal of biological chemistry 1999;274(34):24147-52.
1999: Canonne-Hergaux F; Gruenheid S; Ponka P; Gros P
Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron.
Blood 1999;93(12):4406-17.
1999: Ponka P
Cellular iron metabolism.
Kidney international. Supplement 1999;69():S2-11.
1999: Hermes-Lima M; Santos N C; Yan J; Andrews M; Schulman H M; Ponka P
EPR spin trapping and 2-deoxyribose degradation studies of the effect of pyridoxal isonicotinoyl hydrazone (PIH) on *OH formation by the Fenton reaction.
Biochimica et biophysica acta 1999;1426(3):475-82.
1999: Necas E; Sulc K; Zivný J H; Sýkora V; Ponka P
Red blood cell degradation products modify responsiveness of erythropoietin gene to hypoxia.
Advances in experimental medicine and biology 1999;471():427-37.
1998: Hermes-Lima M; Nagy E; Ponka P; Schulman H M
The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) protects plasmid pUC-18 DNA against *OH-mediated strand breaks.
Free radical biology & medicine 1998;25(8):875-80.
1998: Necas E; Ponka P
Ureter obliteration transiently depresses erythropoietin production.
European journal of clinical investigation 1998;28(11):918-23.
1998: Ponka P; Beaumont C; Richardson D R
Function and regulation of transferrin and ferritin.
Seminars in hematology 1998;35(1):35-54.
1997: Golenser J; Domb A; Teomim D; Tsafack A; Nisim O; Ponka P; Eling W; Cabantchik Z I
The treatment of animal models of malaria with iron chelators by use of a novel polymeric device for slow drug release.
The Journal of pharmacology and experimental therapeutics 1997;281(3):1127-35.
1997: Richardson D R; Ponka P
The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells.
Biochimica et biophysica acta 1997;1331(1):1-40.
1997: Ponka P
Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells.
Blood 1997;89(1):1-25.
1997: Bhattacharya M; Ponka P; Hardy P; Hanna N; Varma D R; Lachapelle P; Chemtob S
Prevention of postasphyxia electroretinal dysfunction with a pyridoxal hydrazone.
Free radical biology & medicine 1997;22(1-2):11-6.
1996: Richardson D R; Ponka P; Vyoral D
Distribution of iron in reticulocytes after inhibition of heme synthesis with succinylacetone: examination of the intermediates involved in iron metabolism.
Blood 1996;87(8):3477-88.
1995: Richardson D R; Tran E H; Ponka P
The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents.
Blood 1995;86(11):4295-306.
1995: Richardson D R; Ponka P
Identification of a mechanism of iron uptake by cells which is stimulated by hydroxyl radicals generated via the iron-catalysed Haber-Weiss reaction.
Biochimica et biophysica acta 1995;1269(2):105-14.
1995: Richardson D R; Neumannova V; Nagy E; Ponka P
The effect of redox-related species of nitrogen monoxide on transferrin and iron uptake and cellular proliferation of erythroleukemia (K562) cells.
Blood 1995;86(8):3211-9.
1995: Richardson D R; Neumannova V; Ponka P
Nitrogen monoxide decreases iron uptake from transferrin but does not mobilise iron from prelabelled neoplastic cells.
Biochimica et biophysica acta 1995;1266(3):250-60.
1994: Richardson D R; Ponka P
The iron metabolism of the human neuroblastoma cell: lack of relationship between the efficacy of iron chelation and the inhibition of DNA synthesis.
The Journal of laboratory and clinical medicine 1994;124(5):660-71.
1994: Hermes-Lima M; Wang E M; Schulman H M; Storey K B; Ponka P
Deoxyribose degradation catalyzed by Fe(III)-EDTA: kinetic aspects and potential usefulness for submicromolar iron measurements.
Molecular and cellular biochemistry 1994;137(1):65-73.
1994: Ponka P; Richardson D R; Edward J T; Chubb F L
Iron chelators of the pyridoxal isonicotinoyl hydrazone class. Relationship of the lipophilicity of the apochelator to its ability to mobilise iron from reticulocytes in vitro.
Canadian journal of physiology and pharmacology 1994;72(6):659-66.
1994: Chan R Y; Seiser C; Schulman H M; Kühn L C; Ponka P
Regulation of transferrin receptor mRNA expression. Distinct regulatory features in erythroid cells.
European journal of biochemistry / FEBS 1994;220(3):683-92.
1994: Richardson D; Ponka P; Baker E
The effect of the iron(III) chelator, desferrioxamine, on iron and transferrin uptake by the human malignant melanoma cell.
Cancer research 1994;54(3):685-9.
1994: Ponka P; Schulman H M
Distinct features of iron metabolism in erythroid cells: implications for heme synthesis regulation.
Advances in experimental medicine and biology 1994;356():173-87.
1993: Chan R Y; Schulman H M; Ponka P
Expression of ferrochelatase mRNA in erythroid and non-erythroid cells.
The Biochemical journal 1993;292 ( Pt 2)():343-9.
1993: Ponka P; Schulman H M
Regulation of heme biosynthesis: distinct regulatory features in erythroid cells.
Stem cells (Dayton, Ohio) 1993;11 Suppl 1():24-35.
1992: Chan R Y; Ponka P; Schulman H M
Transferrin-receptor-independent but iron-dependent proliferation of variant Chinese hamster ovary cells.
Experimental cell research 1992;202(2):326-36.
1989: Schulman H M; Ponka P; Wilczynska A; Gauthier Y; Shyamala G
Transferrin receptor and ferritin levels during murine mammary gland development.
Biochimica et biophysica acta 1989;1010(1):1-6.
1988: Ponka P; Richardson D; Baker E; Schulman H M; Edward J T
Effect of pyridoxal isonicotinoyl hydrazone and other hydrazones on iron release from macrophages, reticulocytes and hepatocytes.
Biochimica et biophysica acta 1988;967(1):122-9.
1988: Laskey J; Webb I; Schulman H M; Ponka P
Evidence that transferrin supports cell proliferation by supplying iron for DNA synthesis.
Experimental cell research 1988;176(1):87-95.
1988: Ponka P; Schulman H M; Martinez-Medellin J
Haem inhibits iron uptake subsequent to endocytosis of transferrin in reticulocytes.
The Biochemical journal 1988;251(1):105-9.
1986: Laskey J D; Ponka P; Schulman H M
Control of heme synthesis during Friend cell differentiation: role of iron and transferrin.
Journal of cellular physiology 1986;129(2):185-92.
1985: Ponka P; Schulman H M
Acquisition of iron from transferrin regulates reticulocyte heme synthesis.
The Journal of biological chemistry 1985;260(27):14717-21.
1985: Ponka P; Schulman H M
Regulation of heme synthesis in erythroid cells: hemin inhibits transferrin iron utilization but not protoporphyrin synthesis.
Blood 1985;65(4):850-7.
1984: Ponka P; Grady R W; Wilczynska A; Schulman H M
The effect of various chelating agents on the mobilization of iron from reticulocytes in the presence and absence of pyridoxal isonicotinoyl hydrazone.
Biochimica et biophysica acta 1984;802(3):477-89.
1984: Wilczynska A; Ponka P; Schulman H M
Transferrin receptors and iron utilization in DMSO-inducible and -uninducible Friend erythroleukemia cells.
Experimental cell research 1984;154(2):561-6.
1982: Ponka P; Schulman H M; Wilczynska A
Ferric pyridoxal isonicotinoyl hydrazone can provide iron for heme synthesis in reticulocytes.
Biochimica et biophysica acta 1982;718(2):151-6.
1982: Ponka P; Wilczynska A; Schulman H M
Iron utilization in rabbit reticulocytes. A study using succinylacetone as an inhibitor or heme synthesis.
Biochimica et biophysica acta 1982;720(1):96-105.
1981: Schulman H M; Ponka P
The stimulation of globin synthesis by cobalt in reticulocytes with inhibited heme synthesis.
Biochimica et biophysica acta 1981;654(1):166-8.
1981: Schulman H M; Wilczynska A; Ponka P
Transferrin and iron uptake by human lymphoblastoid and K-562 cells.
Biochemical and biophysical research communications 1981;100(4):1523-30.

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