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Bernardo Pons-Estel

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David L Morris; Joanne Nititham; Janelle A Noble; Bernardo A Pons-Estel; John D Rioux; Michael F Seldin; Kimberly E Taylor; Marta E Alarcón-Riquelme; Lisa F Barcellos; Timothy W Behrens; Chris Cotsapas; Lindsey A Criswell; Michelle M A Fernando; Patrick M Gaffney; Robert R Graham; Peter K Gregersen; John B Harley; Stephen L Hauser; Geoffrey Hom; Carl D Langefeld; Timothy J Vyse
Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.
G J Pons-Estel; Verónica Saurit; L H Silveira; D Wojdyla; Graciela S Alarcón; J L Alfaro-Lozano; G Boggio; Fernando L Cavalcanti; L T Lavras Costallat; I García de la Torre; M J Sauza Del Pozo; M H Esteva-Spinetti; L A Ramirez Gómez; M Guibert-Toledano; L Hachuel; Loreto Massardo; Bernardo A Pons-Estel
The impact of rural residency on the expression and outcome of systemic lupus erythematosus: data from a multiethnic Latin American cohort.
Mario H Cardiel; Ana Beatriz Cordeiro de Azevedo; Inês Guimarães da Silveira; Jorge A Esquivel-Valerio; Ignacio García-De La Torre; Margarita Portela Hernandez; Vianna J Khoury; Juan Carlos Marcos; Loreto Massardo; Alberto Millán; Rafael Valle Oñate; María Raquel C Pinto; Bernardo A Pons-Estel; Sebastião C Radominski; Adriana Rojas-Villarraga; Mónica P Sacnun; Verónica Saurit; Enrique Roberto Soriano; Daniel Wojdyla; Antônio C Ximenes; Francisco Ballesteros
Treatment of early rheumatoid arthritis in a multinational inception cohort of Latin American patients: the GLADAR experience.

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All Publications

2012: David L Morris; Joanne Nititham; Janelle A Noble; Bernardo A Pons-Estel; John D Rioux; Michael F Seldin; Kimberly E Taylor; Marta E Alarcón-Riquelme; Lisa F Barcellos; Timothy W Behrens; Chris Cotsapas; Lindsey A Criswell; Michelle M A Fernando; Patrick M Gaffney; Robert R Graham; Peter K Gregersen; John B Harley; Stephen L Hauser; Geoffrey Hom; Carl D Langefeld; Timothy J Vyse
Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans.
American journal of human genetics 2012;91(5):778-93.
2012: G J Pons-Estel; Verónica Saurit; L H Silveira; D Wojdyla; Graciela S Alarcón; J L Alfaro-Lozano; G Boggio; Fernando L Cavalcanti; L T Lavras Costallat; I García de la Torre; M J Sauza Del Pozo; M H Esteva-Spinetti; L A Ramirez Gómez; M Guibert-Toledano; L Hachuel; Loreto Massardo; Bernardo A Pons-Estel
The impact of rural residency on the expression and outcome of systemic lupus erythematosus: data from a multiethnic Latin American cohort.
Lupus 2012;21(13):1397-404.
2012: Mario H Cardiel; Ana Beatriz Cordeiro de Azevedo; Inês Guimarães da Silveira; Jorge A Esquivel-Valerio; Ignacio García-De La Torre; Margarita Portela Hernandez; Vianna J Khoury; Juan Carlos Marcos; Loreto Massardo; Alberto Millán; Rafael Valle Oñate; María Raquel C Pinto; Bernardo A Pons-Estel; Sebastião C Radominski; Adriana Rojas-Villarraga; Mónica P Sacnun; Verónica Saurit; Enrique Roberto Soriano; Daniel Wojdyla; Antônio C Ximenes; Francisco Ballesteros
Treatment of early rheumatoid arthritis in a multinational inception cohort of Latin American patients: the GLADAR experience.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2012;18(7):327-35.
2012: Loreto Massardo; Rubén A Montufar; Oslando Padilla; Carlos Pineda; Bernardo A Pons-Estel; Luis A Ramírez; Mónica P Sacnun; Enrique R Soriano; Daniel Wojdyla; Eduardo M Acevedo-Vásquez; Angel F Achurra-Castillo; Carlo V Caballero-Uribe; Mario H Cardiel; Licia M da Mota; José F Díaz-Coto; María H Esteva-Spinetti; Claudio M Galarza-Maldonado; Zoila M Guibert-Toledano; Jaime A Hernández; Ieda M Laurindo; Leticia Lino-Pérez; Daniel E Furst
Early rheumatoid arthritis in Latin America: low socioeconomic status related to high disease activity at baseline.
Arthritis care & research 2012;64(8):1135-43.
2012: Angelica Maria Delgado-Vega; Mikhail G Dozmorov; Emoke Endreffy; Johan Frostegård; María Francisca González-Escribano; László Kovács; Sergey V Kozyrev; Bernard R Lauwerys; Javier Martin; Belén Martínez-García; Norberto Ortego Centeno; Bernardo A Pons-Estel; Manuel Bernal Quirós; Gian Domenico Sebastiani; Lennart Truedsson; Carlos Vasconcelos; Torsten Witte; Jonathan Wren; Ying-Yu Wu; Casimiro Castillejo-López; Berta Martins da Silva; Sandra D'Alfonso; Enrique de Ramón; Marta E Alarcón-Riquelme
Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein.
Annals of the rheumatic diseases 2012;71(7):1219-26.
2012: Guillermo J Pons-Estel; Verónica Saurit; Maria J Sauza Del Pozo; Enrique R Soriano; Daniel Wojdyla; Graciela S Alarcón; Magaly Alva; Mary-Carmen Amigo; Gabriela Boggio; Fernando S Cavalcanti; Maria H Esteva-Spinetti; Marlene Guibert-Toledano; Renato A Guzman; Leticia Hachuel; Virginia Pascual-Ramos; Bernardo A Pons-Estel
Anti-malarials exert a protective effect while Mestizo patients are at increased risk of developing SLE renal disease: data from a Latin-American cohort.
Rheumatology (Oxford, England) 2012;51(7):1293-8.
2012: S E Löfgren; B Martins da Silva; Bernardo A Pons-Estel; Lennart Truedsson; C Vasconcelos; T Witte; Sandra D'Alfonso; Emoke Endreffy; J Frostegård; L Kovács; Sergey V Kozyrev; B R Lauwerys; Marta E Alarcón-Riquelme
Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene.
Genes and immunity 2012;13(3):268-74.
2012: Casimiro Castillejo-López; Sandra D'Alfonso; Angelica Maria Delgado-Vega; Nicolás Domínguez; Serena Fineschi; Johan Frostegård; Patrick M Gaffney; Gary Gilkeson; Guthridge Joel; John B Harley; Judith A James; Kenneth M Kaufman; Jennifer A Kelly; Sergey V Kozyrev; Juan R López-Egido; Rufei Lu; Javier Martin; Joan T Merrill; Kathy L Moser; David Pöllmann; Bernardo A Pons-Estel; Elena Sanchez; Elangovan Thavathiru; Torsten Witte; Jerome Wojcik; Ying-Yu Wu; José Luis Callejas; Marta E Alarcón-Riquelme
Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
Annals of the rheumatic diseases 2012;71(1):136-42.
2011: Antoine Sreih; Lakshman Subrahmanyan; Elisabet Svenungsson; Geraldine Yu; Lin Zhang; Anna-Karin Abelson; Marta E Alarcón-Riquelme; Joshua Cavett; Rana Ezzeddine; Stuart Glenn; Iva Gunnarsson; John B Harley; Avery LaChance; Lin Leng; Yuka Mizue; Ruth Montgomery; Andras Perl; Bernardo A Pons-Estel; Jane Salmon; Richard Bucala
Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus.
Arthritis and rheumatism 2011;63(12):3942-51.
2011: Mónica P Sacnun; Jaime Ferrer; Marisol Ferrer; Bernardo A Pons-Estel
[Rapidly progressive fatal interstitial lung disease in a patient with an overlap syndrome of systemic lupus erythematosus and systemic sclerosis].
Reumatología clinica 2011;7(1):61-7.
2010: Elena Sanchez; Ryan D Webb; Astrid Rasmussen; Jennifer A Kelly; Laura Riba; Kenneth M Kaufman; Ignacio Garcia-De la Torre; Jose F Moctezuma; Marco A Maradiaga-Ceceña; Mario H Cardiel-Rios; Eduardo Acevedo; Mariano Cucho-Venegas; Mercedes A Garcia; Susana Gamron; Bernardo A Pons-Estel; Carlos Vasconcelos; Javier Martin; Teresa Tusié-Luna; John B Harley; Bruce C Richardson; Amr H Sawalha; Marta E Alarcón-Riquelme
Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.
Arthritis and rheumatism 2010;62(12):3722-9.
2010: Sara E Löfgren; Angelica Maria Delgado-Vega; Caroline J Gallant; Elena Sanchez; Johan Frostegård; Lennart Truedsson; Enrique de Ramón Garrido; José M Sabio; María Francisca González-Escribano; Bernardo A Pons-Estel; Sandra D'Alfonso; Torsten Witte; Bernard R Lauwerys; Emoke Endreffy; László Kovács; Carlos Vasconcelos; Berta Martins da Silva; Javier Martín; Marta E Alarcón-Riquelme; Sergey V Kozyrev
A 3'-untranslated region variant is associated with impaired expression of CD226 in T and natural killer T cells and is associated with susceptibility to systemic lupus erythematosus.
Arthritis and rheumatism 2010;62(11):3404-14.
2010: Samuel K Shinjo; Eloísa Bonfá; Daniel Wojdyla; Eduardo F Borba; Luis A Ramirez; Hugo R Scherbarth; João C Tavares Brenol; Rosa Chacón-Diaz; Oscar J Neira; Guillermo A Berbotto; Ignacio Garcia De La Torre; Eduardo M Acevedo-Vázquez; Loreto Massardo; Leonor A Barile-Fabris; Francisco Caeiro; Luis H Silveira; Emilia I Sato; Sandra Buliubasich; Graciela S Alarcón; Bernardo A Pons-Estel
Antimalarial treatment may have a time-dependent effect on lupus survival: data from a multinational Latin American inception cohort.
Arthritis and rheumatism 2010;62(3):855-62.
2010: Sara E Löfgren; Hong Yin; Angelica Maria Delgado-Vega; Elena Sanchez; Susanna Lewén; Bernardo A Pons-Estel; Torsten Witte; Sandra D'Alfonso; Norberto Ortego Centeno; Javier Martin; Marta E Alarcón-Riquelme; Sergey V Kozyrev
Promoter insertion/deletion in the IRF5 gene is highly associated with susceptibility to systemic lupus erythematosus in distinct populations, but exerts a modest effect on gene expression in peripheral blood mononuclear cells.
The Journal of rheumatology 2010;37(3):574-8.
2009: A-K Abelson; Angelica Maria Delgado-Vega; Sergey V Kozyrev; Elena Sanchez; Rafael Velázquez-Cruz; N Eriksson; J Wojcik; M V P Linga Reddy; Guadalupe Lima; Sandra D'Alfonso; Sergio Migliaresi; Vicente Baca; L Orozco; T Witte; Norberto Ortego Centeno; H Abderrahim; Bernardo A Pons-Estel; C Gutiérrez; A Suárez; María Francisca González-Escribano; J Martin; Marta E Alarcón-Riquelme
STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk.
Annals of the rheumatic diseases 2009;68(11):1746-53.
2009: Elena Sánchez; Rogelio J Palomino-Morales; Norberto Ortego Centeno; Juan Jiménez-Alonso; Miguel A González-Gay; Miguel A López-Nevot; Julio Sánchez Román; Enrique de Ramón; María Francisca González-Escribano; Bernardo A Pons-Estel; Sandra D'Alfonso; Gian Domenico Sebastiani; Marta E Alarcón-Riquelme; Javier Martín
Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus.
Human molecular genetics 2009;18(19):3739-48.
2009: Loreto Massardo; María E Suárez-Almazor; Mario H Cardiel; Arnulfo Nava; Roger levy; Ieda Laurindo; Enrique R Soriano; Eduardo Acevedo-Vázquez; Alberto Millán; Carlos Pineda-Villaseñor; Claudio Galarza-Maldonado; Carlo V Caballero-Uribe; Rolando Espinosa-Morales; Bernardo A Pons-Estel
Management of patients with rheumatoid arthritis in Latin America: a consensus position paper from Pan-American League of Associations of Rheumatology and Grupo Latino Americano De Estudio De Artritis Reumatoide.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 2009;15(4):203-10.
2009: Angelica Maria Delgado-Vega; A-K Abelson; Elena Sanchez; T Witte; Sandra D'Alfonso; Mauro Galeazzi; J Jiménez-Alonso; Bernardo A Pons-Estel; J Martin; Marta E Alarcón-Riquelme
Replication of the TNFSF4 (OX40L) promoter region association with systemic lupus erythematosus.
Genes and immunity 2009;10(3):248-53.
2008: Michael F Seldin; Lihong Qi; Hugo R Scherbarth; Chao Tian; M Ransom; G Silva; John W Belmont; Susana Gamron; A Allievi; Simon A Palatnik; V Saurit; Sergio Paira; C Graf; C Guillerón; Luis Catoggio; C Prigione; Guillermo A Berbotto; Mercedes A García; Carlos E Perandones; Lennart Truedsson; H Abderrahim; C G Battagliotti; Bernardo A Pons-Estel; Marta Eugenia ALARCON-RIQUELME
Amerindian ancestry in Argentina is associated with increased risk for systemic lupus erythematosus.
Genes and immunity 2008;9(4):389-93.
2008: Sergey V Kozyrev; Anna-Karin Abelson; Jerome Wojcik; Ammar Zaghlool; Mv Prasad Linga Reddy; Elena Sanchez; Iva Gunnarsson; Elisabet Svenungsson; Gunnar Sturfelt; Andreas Jönsen; Lennart Truedsson; Bernardo A Pons-Estel; Torsten Witte; Sandra D'Alfonso; Nadia Barrizzone; Maria Giovanna Danieli; Carmen Gutierrez; Ana Suarez; Peter Junker; Henrik K Laustrup; Maria Francisca González-Escribano; Javier Martin; Hadi Abderrahim; Marta E Alarcón-Riquelme
Corrigendum: Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.
Nature genetics 2008;40(4):484.
2008: Sergey V Kozyrev; Anna-Karin Abelson; Jerome Wojcik; Ammar Zaghlool; M V Prasad Linga Reddy; Elena Sanchez; Iva Gunnarsson; Elisabet Svenungsson; Gunnar Sturfelt; Andreas Jönsen; Lennart Truedsson; Bernardo A Pons-Estel; Torsten Witte; Sandra D'Alfonso; Nadia Barizzone; Nadia Barrizzone; Maria Giovanna Danieli; Carmen Gutierrez; Ana Suarez; Peter Junker; Henrik K Laustrup; María Francisca González-Escribano; Javier Martin; Hadi Abderrahim; Marta E Alarcón-Riquelme
Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.
Nature genetics 2008;40(2):211-6.
2007: Sergey V Kozyrev; Susanna Lewén; Prasad M V Linga Reddy; Bernardo A Pons-Estel; Torsten Witte; Peter Junker; Henrik K Laustrup; Carmen Gutiérrez; Ana Suárez; Maria Francisca González-Escribano; Javier Martín; Marta E Alarcón-Riquelme
Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus.
Arthritis and rheumatism 2007;56(4):1234-41.
2007: Michael F Seldin; Chao Tian; Russell Shigeta; Hugo R Scherbarth; Gabriel Silva; John W Belmont; Rick Kittles; Susana Gamron; Alberto Allevi; Simon A Palatnik; Alejandro Alvarellos; Sergio Paira; Cesar Caprarulo; Carolina Guillerón; Luis Catoggio; Cristina Prigione; Guillermo A Berbotto; Mercedes A García; Carlos E Perandones; Bernardo A Pons-Estel; Marta Eugenia ALARCON-RIQUELME
Argentine population genetic structure: large variance in Amerindian contribution.
American journal of physical anthropology 2007;132(3):455-62.
2007: A K Abelson; Cecilia M Johansson; Sergey V Kozyrev; Helga Kristjansdottir; Iva Gunnarsson; Elisabet Svenungsson; Andreas Jönsen; Guadalupe Lima; Hugo R Scherbarth; Susana Gamron; A Allievi; Simon A Palatnik; Alejandro Alvarellos; Sergio Paira; C Graf; C Guillerón; Luis Catoggio; C Prigione; C G Battagliotti; Guillermo A Berbotto; Mercedes A García; Carlos E Perandones; Lennart Truedsson; Kristjan Steinsson; Gunnar Sturfelt; Bernardo A Pons-Estel; Marta E Alarcón-Riquelme
No evidence of association between genetic variants of the PDCD1 ligands and SLE.
Genes and immunity 2007;8(1):69-74.
2006: Blanca Rueda; M V Prasad Linga Reddy; Miguel A González-Gay; Alejandro Balsa; Dora Pascual-Salcedo; Ingemar F Petersson; Alicia Eimon; Sergio Paira; Hugo R Scherbarth; Bernardo A Pons-Estel; María Francisca González-Escribano; Marta E Alarcón-Riquelme; Javier Martín
Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis.
Arthritis and rheumatism 2006;54(12):3815-9.
2006: Gisela Orozco; Gema Robledo; M V P Linga Reddy; A García; Dora Pascual-Salcedo; Alejandro Balsa; Miguel A González-Gay; A Eimon; Sergio Paira; Hugo R Scherbarth; Bernardo A Pons-Estel; I F Petersson; Marta E Alarcón-Riquelme; Javier Martín
Study of the role of a functional polymorphism of MHC2TA in rheumatoid arthritis in three ethnically different populations.
Rheumatology (Oxford, England) 2006;45(11):1442-4.
2006: Robert R Graham; Sergey V Kozyrev; Emily C Baechler; M V Prasad Linga Reddy; Robert M Plenge; Jason W Bauer; Ward A Ortmann; Thearith Koeuth; María Francisca González-Escribano; Bernardo A Pons-Estel; Michelle Petri; Mark J Daly; Peter K Gregersen; Javier Martín; David Altshuler; timothy wayne behrens; Marta E Alarcón-Riquelme
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus.
Nature genetics 2006;38(5):550-5.
2005: Donato Alarcón-Segovia; Marta E Alarcón-Riquelme; Mario H Cardiel; Francisco Caeiro; Loreto Massardo; Antonio R Villa; Bernardo A Pons-Estel
Familial aggregation of systemic lupus erythematosus, rheumatoid arthritis, and other autoimmune diseases in 1,177 lupus patients from the GLADEL cohort.
Arthritis and rheumatism 2005;52(4):1138-47.
2005: M A Garcia; J C Marcos; A I Marcos; Bernardo A Pons-Estel; D Wojdyla; A Arturi; J C Babini; Luis Catoggio; D Alarcon-Segovia
Male systemic lupus erythematosus in a Latin-American inception cohort of 1214 patients.
Lupus 2005;14(12):938-46.
2004: Cecilia M Johansson; Renata Zunec; Mercedes A García; Hugo R Scherbarth; Guillermo A Tate; Sergio Paira; Sandra M Navarro; Carlos E Perandones; Susana Gamron; Alejandro Alvarellos; Cesar E Graf; Jorge Manni; Guillermo A Berbotto; Simon A Palatnik; Luis Catoggio; Cristina G Battagliotti; gian domenico sebastiani; Sergio Migliaresi; Mauro Galeazzi; Bernardo A Pons-Estel; Marta E Alarcón-Riquelme
Chromosome 17p12-q11 harbors susceptibility loci for systemic lupus erythematosus.
Human genetics 2004;115(3):230-8.
2004: Bernardo A Pons-Estel; Luis Catoggio; Mario H Cardiel; Enrique R Soriano; Silvana Gentiletti; Antonio R Villa; Isaac Abadi; Francisco Caeiro; Alejandro Alvarellos; Donato Alarcón-Segovia
The GLADEL multinational Latin American prospective inception cohort of 1,214 patients with systemic lupus erythematosus: ethnic and disease heterogeneity among "Hispanics".
Medicine 2004;83(1):1-17.
2001: Ivona Aksentijevich; Jérôme Galon; M Soares; Elizabeth Mansfield; Keith M Hull; H H Oh; Raphaela Goldbach-Mansky; Jurrien Dean; B Athreya; A J Reginato; M Henrickson; Bernardo A Pons-Estel; John O'Shea; Daniel Kastner
The tumor-necrosis-factor receptor-associated periodic syndrome: new mutations in TNFRSF1A, ancestral origins, genotype-phenotype studies, and evidence for further genetic heterogeneity of periodic fevers.
American journal of human genetics 2001;69(2):301-14.
2001: E Acevedo; O Castañeda; M Ugaz; A D Beaulieu; Bernardo A Pons-Estel; F Caeiro; N Casas; M Garza-Elizondo; F Irazoque; W Hinojosa; S Gutierrez-Ureña; K Vandormael; Diana B Rodgers; M Laurenzi
Tolerability profiles of rofecoxib (Vioxx) and Arthrotec. A comparison of six weeks treatment in patients with osteoarthritis.
Scandinavian journal of rheumatology 2001;30(1):19-24.
2000: Bernardo A Pons-Estel; C Gimenez; M Sacnun; S Gentiletti; C A Battagliotti; L S de la Pena; Charlene J Williams; Antonio J Reginato
Familial osteoarthritis and Milwaukee shoulder associated with calcium pyrophosphate and apatite crystal deposition.
The Journal of rheumatology 2000;27(2):471-80.