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Angela Popham

Research Profile

Chemicals & Drugs

Physiology

Allosteric Regulation

Anatomy

CHO Cells

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Allosteric Sites

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Publications

TOP 3
Sebastian Lazareno; V Dolezal; Angela Popham; Nigel J M Birdsall
Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity.
Sebastian Lazareno; Angela Popham; Nigel J M Birdsall
Progress toward a high-affinity allosteric enhancer at muscarinic M1 receptors.
Sebastian Lazareno; Angela Popham; Nigel J M Birdsall
Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors.

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All Publications

2004: Sebastian Lazareno; V Dolezal; Angela Popham; Nigel J M Birdsall
Thiochrome enhances acetylcholine affinity at muscarinic M4 receptors: receptor subtype selectivity via cooperativity rather than affinity.
Molecular pharmacology 2004;65(1):257-66.
2003: Sebastian Lazareno; Angela Popham; Nigel J M Birdsall
Progress toward a high-affinity allosteric enhancer at muscarinic M1 receptors.
Journal of molecular neuroscience : MN 2003;20(3):363-7.
2002: Sebastian Lazareno; Angela Popham; Nigel J M Birdsall
Analogs of WIN 62,577 define a second allosteric site on muscarinic receptors.
Molecular pharmacology 2002;62(6):1492-505.
2002: Sebastian Lazareno; Angela Popham; Nigel J M Birdsall
Towards a high-affinity allosteric enhancer at muscarinic M1 receptors.
Journal of molecular neuroscience : MN 2002;19(1-2):123-7.
2002: Parviz Gharagozloo; Sebastian Lazareno; Masao Miyauchi; Angela Popham; Nigel J M Birdsall
Substituted pentacyclic carbazolones as novel muscarinic allosteric agents: synthesis and structure-affinity and cooperativity relationships.
Journal of medicinal chemistry 2002;45(6):1259-74.
2001: Nigel J M Birdsall; Sebastian Lazareno; Angela Popham; José W Saldanha
Multiple allosteric sites on muscarinic receptors.
Life sciences 2001;68(22-23):2517-24.
2000: Sebastian Lazareno; Angela Popham; Nigel J M Birdsall
Allosteric interactions of staurosporine and other indolocarbazoles with N-[methyl-(3)H]scopolamine and acetylcholine at muscarinic receptor subtypes: identification of a second allosteric site.
Molecular pharmacology 2000;58(1):194-207.
1999: Parviz Gharagozloo; Sebastian Lazareno; Angela Popham; Nigel J M Birdsall
Allosteric interactions of quaternary strychnine and brucine derivatives with muscarinic acetylcholine receptors.
Journal of medicinal chemistry 1999;42(3):438-45.
1999: Sebastian Lazareno; B Birdsall; T Fukazawa; Parviz Gharagozloo; T Hashimoto; H Kuwano; Angela Popham; M Sugimoto; Nigel J M Birdsall
Allosteric effects of four stereoisomers of a fused indole ring system with 3H-N-methylscopolamine and acetylcholine at M1-M4 muscarinic receptors.
Life sciences 1999;64(6-7):519-26.
1998: Sebastian Lazareno; Angela Popham; Nigel J M Birdsall
Muscarinic interactions of bisindolylmaleimide analogues.
European journal of pharmacology 1998;360(2-3):281-4.
1998: Sebastian Lazareno; Parviz Gharagozloo; D Kuonen; Angela Popham; Nigel J M Birdsall
Subtype-selective positive cooperative interactions between brucine analogues and acetylcholine at muscarinic receptors: radioligand binding studies.
Molecular pharmacology 1998;53(3):573-89.
1997: Nigel J M Birdsall; T Farries; Parviz Gharagozloo; S Kobayashi; D Kuonen; Sebastian Lazareno; Angela Popham; M Sugimoto
Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes.
Life sciences 1997;60(13-14):1047-52.
1989: D W Dresser; Angela Popham; N E Herrera; J Carter
Immunoglobulin-secreting cells in close proximity to the mid-gestation mouse embryo.
Journal of reproductive immunology 1989;16(1):55-70.
1985: R J Hancock; Angela Popham; S Faruki; D W Dresser
Increases in the numbers of immunoglobulin-secreting cells in lymph nodes responding to sperm and other stimuli: possible relationship to immunosuppression.
Immunology 1985;55(2):233-9.
1983: D W Dresser; R M Parkhouse; Angela Popham
Pretreatment of mice with anti-IgD serum does not result in suppression of immune responsiveness induced by TNP-AECM-Ficoll or lipopolysaccharide.
Immunology 1983;48(3):497-501.
1982: D W Dresser; Angela Popham; R Hunt
Differences in putative minor histocompatibility but not IgH genes can prevent T-cell priming and T--B co-operation in the response of mice to sheep erythrocytes.
Immunology 1982;46(3):643-51.
1980: D W Dresser; Angela Popham
Rheumatoid factors in mice: plaque assay for homophile and heterophile rheumatoid factors.
Immunology 1980;41(3):569-77.
1980: Angela Popham; D W Dresser
Rheumatoid factors in mice: non-specific activators of heterophile rheumatoid factor production.
Immunology 1980;41(3):579-85.