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Corine Bertolotto

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Caroline Bonet; Sandy Giuliano; Jean-Philippe Lacour; Mickael Ohanna; Stéphane Rocchi; Maryline Allegra; Philippe Bahadoran; Robert Ballotti; Karine Bille; Corine Bertolotto
Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.
Yann Cheli; N Fenouille; S Giuliano; Paul Hofman; Véronique Hofman; J-P Lacour; Sophie Tartare-Deckert; M Allegra; Philippe Bahadoran; Corine Bertolotto; Robert Ballotti
Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells.
Laurent Beuret; Irwin Davidson; Mickael Ohanna; Thomas Strub; Maryline Allegra; Corine Bertolotto; Robert Ballotti
BRCA1 is a new MITF target gene.

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All Publications

2012: Caroline Bonet; Sandy Giuliano; Jean-Philippe Lacour; Mickael Ohanna; Stéphane Rocchi; Maryline Allegra; Philippe Bahadoran; Robert Ballotti; Karine Bille; Corine Bertolotto
Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.
The Journal of biological chemistry 2012;287(35):29887-98.
2012: Yann Cheli; N Fenouille; S Giuliano; Paul Hofman; Véronique Hofman; J-P Lacour; Sophie Tartare-Deckert; M Allegra; Philippe Bahadoran; Corine Bertolotto; Robert Ballotti
Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells.
Oncogene 2012;31(19):2461-70.
2011: Laurent Beuret; Irwin Davidson; Mickael Ohanna; Thomas Strub; Maryline Allegra; Corine Bertolotto; Robert Ballotti
BRCA1 is a new MITF target gene.
Pigment cell & melanoma research 2011;24(4):725-7.
2011: Mickael Ohanna; Jean-François Peyron; Caroline Robert; Stéphane Rocchi; Joséphine Zangari; Robert Ballotti; Karine Bille; Caroline Bonet; Brigitte Bressac De-Paillerets; Sandy Giuliano; Paul Hofman; Véronique Hofman; Véronique Imbert; Jean-Philippe Lacour; Corine Bertolotto
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS).
Genes & development 2011;25(12):1245-61.
2011: Y Cheli; S Guiliano; T Botton; Stéphane Rocchi; Véronique Hofman; Paul Hofman; Philippe Bahadoran; Corine Bertolotto; S Giuliano; Robert Ballotti
Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny.
Oncogene 2011;30(20):2307-18.
2011: T Tomic; Sophie Tartare-Deckert; M Allegra; Patrick Auberger; Philippe Bahadoran; Robert Ballotti; J-M Bereder; Corine Bertolotto; T Botton; M Cerezo; P Gounon; Frederic Luciano; A Puissant; Guillaume ROBERT; Stéphane Rocchi
Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.
Cell death & disease 2011;2():e199.
2010: Sandy Giuliano; Yann Cheli; Mickael Ohanna; Caroline Bonet; Laurent Beuret; Karine Bille; Agnès Loubat; Véronique Hofman; Paul Hofman; Gilles Ponzio; Philippe Bahadoran; Robert Ballotti; Corine Bertolotto
Microphthalmia-associated transcription factor controls the DNA damage response and a lineage-specific senescence program in melanomas.
Cancer research 2010;70(9):3813-22.
2010: Issam Ben Sahra; Kathiane Laurent; Sandy Giuliano; Frédéric Larbret; Gilles Ponzio; Pierre GOUNON; Yannick Le Marchand-Brustel; Sophie Giorgetti-Peraldi; Mireille Cormont; Corine Bertolotto; Marcel Deckert; Patrick Auberger; Jean-François Tanti; Frédéric Bost
Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells.
Cancer research 2010;70(6):2465-75.
2008: Caroline Hilmi; Lionel Larribere; Sandy Giuliano; Karine Bille; Jean-Paul Ortonne; Robert Ballotti; Corine Bertolotto
IGF1 promotes resistance to apoptosis in melanoma cells through an increased expression of BCL2, BCL-X(L), and survivin.
The Journal of investigative dermatology 2008;128(6):1499-505.
2008: C Hilmi; Lionel Larribere; M Deckert; S Rocchi; S Giuliano; Karine Bille; Jean-Paul Ortonne; Robert Ballotti; Corine Bertolotto
Involvement of FKHRL1 in melanoma cell survival and death.
Pigment cell & melanoma research 2008;21(2):139-46.
2007: Thierry Passeron; Julio C Valencia; Corine Bertolotto; Toshihiko Hoashi; Elodie Le Pape; Kaoruko Takahashi; Robert Ballotti; Vincent J Hearing
SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):13984-9.
2007: Laurent Beuret; Enrica Flori; Christophe Denoyelle; Karine Bille; Roser Busca; Mauro Picardo; Corine Bertolotto; Robert Ballotti
Up-regulation of MET expression by alpha-melanocyte-stimulating hormone and MITF allows hepatocyte growth factor to protect melanocytes and melanoma cells from apoptosis.
The Journal of biological chemistry 2007;282(19):14140-7.
2007: Cedric Gaggioli; Guillaume ROBERT; Corine Bertolotto; Olivier Bailet; Patricia Abbe; Anne Spadafora; Philippe Bahadoran; Jean-Paul Ortonne; Véronique Baron; Robert Ballotti; Sophie Tartare-Deckert
Tumor-derived fibronectin is involved in melanoma cell invasion and regulated by V600E B-Raf signaling pathway.
The Journal of investigative dermatology 2007;127(2):400-10.
2005: Lionel Larribere; Caroline Hilmi; Mehdi Khaled; Cedric Gaggioli; Karine Bille; Patrick Auberger; Jean-Paul Ortonne; Robert Ballotti; Corine Bertolotto
The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis.
Genes & development 2005;19(17):1980-5.
2005: Roser Buscà; Edurne Berra; Cedric Gaggioli; Mehdi Khaled; Karine Bille; Barbara Marchetti; Raphaël Thyss; Giorgos Fitsialos; Lionel Larribère; Corine Bertolotto; Thierry Virolle; Pascal Barbry; Jacques Pouysségur; Gilles Ponzio; Robert Ballotti
Hypoxia-inducible factor 1{alpha} is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells.
The Journal of cell biology 2005;170(1):49-59.
2004: Lionel Larribere; Mehdi Khaled; Sophie Tartare-Deckert; Roser Busca; Frederic Luciano; Karine Bille; Gäelle Valony; A Eychene; Patrick Auberger; Jean-Paul Ortonne; Robert Ballotti; Corine Bertolotto
PI3K mediates protection against TRAIL-induced apoptosis in primary human melanocytes.
Cell death and differentiation 2004;11(10):1084-91.
2004: Thierry Passeron; Philippe Bahadoran; Corine Bertolotto; Christine Chiaverini; Roser Buscà; Gäelle Valony; Karine Bille; Jean-Paul Ortonne; Robert Ballotti
Cyclic AMP promotes a peripheral distribution of melanosomes and stimulates melanophilin/Slac2-a and actin association.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(9):989-91.
2003: Mehdi Khaled; Lionel Larribere; Karine Bille; Jean-Paul Ortonne; Robert Ballotti; Corine Bertolotto
Microphthalmia associated transcription factor is a target of the phosphatidylinositol-3-kinase pathway.
The Journal of investigative dermatology 2003;121(4):831-6.
2002: Mehdi Khaled; Lionel Larribere; Karine Bille; Edith Aberdam; Jean-Paul Ortonne; Robert Ballotti; Corine Bertolotto
Glycogen synthase kinase 3beta is activated by cAMP and plays an active role in the regulation of melanogenesis.
The Journal of biological chemistry 2002;277(37):33690-7.
2002: Frederic Luciano; Jean-Ehrland Ricci; Magali Herrant; Corine Bertolotto; Bernard Mari; J L Cousin; Patrick Auberger
T and B leukemic cell lines exhibit different requirements for cell death: correlation between caspase activation, DFF40/DFF45 expression, DNA fragmentation and apoptosis in T cell lines but not in Burkitt's lymphoma.
Leukemia 2002;16(4):700-7.
2001: Matthew L Bilodeau; J D Greulich; Ronald L Hullinger; Corine Bertolotto; Robert Ballotti; Ourania M Andrisani
BMP-2 stimulates tyrosinase gene expression and melanogenesis in differentiated melanocytes.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2001;14(5):328-36.
2001: L Maulon; Bernard Mari; Corine Bertolotto; Jean-Ehrland Ricci; Frederic Luciano; Nathalie Belhacene; Marcel Deckert; G Baier; Patrick Auberger
Differential requirements for ERK1/2 and P38 MAPK activation by thrombin in T cells. Role of P59Fyn and PKCepsilon.
Oncogene 2001;20(16):1964-72.
2001: Jean-Ehrland Ricci; L Maulon; V Battaglione-Hofman; Corine Bertolotto; Frederic Luciano; Bernard Mari; Paul Hofman; Patrick Auberger
A Jurkat T cell variant resistant to death receptor-induced apoptosis. Correlation with heat shock protein (Hsp) 27 and 70 levels.
European cytokine network 2001;12(1):126-34.
2000: Corine Bertolotto; L Maulon; Nathalie Filippa; G Baier; Patrick Auberger
Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD.
The Journal of biological chemistry 2000;275(47):37246-50.
2000: Corine Bertolotto; Jean-Ehrland Ricci; Frederic Luciano; Bernard Mari; J C Chambard; Patrick Auberger
Cleavage of the serum response factor during death receptor-induced apoptosis results in an inhibition of the c-FOS promoter transcriptional activity.
The Journal of biological chemistry 2000;275(17):12941-7.
2000: C Verastegui; Corine Bertolotto; Karine Bille; Patricia Abbe; Jean-Paul Ortonne; Robert Ballotti
TFE3, a transcription factor homologous to microphthalmia, is a potential transcriptional activator of tyrosinase and TyrpI genes.
Molecular endocrinology (Baltimore, Md.) 2000;14(3):449-56.
1999: Walter Englaro; Philippe Bahadoran; Corine Bertolotto; Roser Buscà; Benoît Dérijard; Antonia Livolsi; Jean-François Peyron; Jean-Paul Ortonne; Robert Ballotti
Tumor necrosis factor alpha-mediated inhibition of melanogenesis is dependent on nuclear factor kappa B activation.
Oncogene 1999;18(8):1553-9.
1998: Corine Bertolotto; Patricia Abbe; TJ Hemesath; Karine Bille; David E Fisher; Jean-Paul Ortonne; Robert Ballotti
Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes.
The Journal of cell biology 1998;142(3):827-35.
1998: Edith Aberdam; Corine Bertolotto; Elena V Sviderskaya; V de Thillot; TJ Hemesath; David E Fisher; Dorothy C Bennett; Jean-Paul Ortonne; Robert Ballotti
Involvement of microphthalmia in the inhibition of melanocyte lineage differentiation and of melanogenesis by agouti signal protein.
The Journal of biological chemistry 1998;273(31):19560-5.
1998: Roser Buscà; Corine Bertolotto; Patricia Abbe; Walter Englaro; T Ishizaki; S Narumiya; P Boquet; Jean-Paul Ortonne; Robert Ballotti
Inhibition of Rho is required for cAMP-induced melanoma cell differentiation.
Molecular biology of the cell 1998;9(6):1367-78.
1998: Walter Englaro; Corine Bertolotto; Roser Buscà; A Brunet; G Pagès; Jean-Paul Ortonne; Robert Ballotti
Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation.
The Journal of biological chemistry 1998;273(16):9966-70.
1998: Corine Bertolotto; Karine Bille; Jean-Paul Ortonne; Robert Ballotti
In B16 melanoma cells, the inhibition of melanogenesis by TPA results from PKC activation and diminution of microphthalmia binding to the M-box of the tyrosinase promoter.
Oncogene 1998;16(13):1665-70.
1998: Corine Bertolotto; Roser Buscà; Patricia Abbe; Karine Bille; Edith Aberdam; Jean-Paul Ortonne; Robert Ballotti
Different cis-acting elements are involved in the regulation of TRP1 and TRP2 promoter activities by cyclic AMP: pivotal role of M boxes (GTCATGTGCT) and of microphthalmia.
Molecular and cellular biology 1998;18(2):694-702.
1996: Roser Buscà; Corine Bertolotto; Jean-Paul Ortonne; Robert Ballotti
Inhibition of the phosphatidylinositol 3-kinase/p70(S6)-kinase pathway induces B16 melanoma cell differentiation.
The Journal of biological chemistry 1996;271(50):31824-30.
1996: Corine Bertolotto; Karine Bille; Jean-Paul Ortonne; Robert Ballotti
Regulation of tyrosinase gene expression by cAMP in B16 melanoma cells involves two CATGTG motifs surrounding the TATA box: implication of the microphthalmia gene product.
The Journal of cell biology 1996;134(3):747-55.