Lourival Possani

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Corzo Gerardo; Prochnicka-Chalufour Ada; García Blanca I; Possani Lourival D; Delepierre Muriel
Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus.
Papp Ferenc; Batista Cesar V F; Varga Zoltan; Herceg Monika; Román-González Sergio A; Gaspar Rezso; Possani Lourival D; Panyi Gyorgy
Tst26, a novel peptide blocker of Kv1.2 and Kv1.3 channels from the venom of Tityus stigmurus.
Silva Edelyn C N; Camargos Thalita S; Maranhão Andrea Q; Silva-Pereira Ildinete; Silva Luciano P; Possani Lourival D; Schwartz Elisabeth F
Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum.

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All Publications

2009: Corzo Gerardo; Prochnicka-Chalufour Ada; García Blanca I; Possani Lourival D; Delepierre Muriel
Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus.
Biochimica et biophysica acta 2009;1794(11):1591-8.
2009: Papp Ferenc; Batista Cesar V F; Varga Zoltan; Herceg Monika; Román-González Sergio A; Gaspar Rezso; Possani Lourival D; Panyi Gyorgy
Tst26, a novel peptide blocker of Kv1.2 and Kv1.3 channels from the venom of Tityus stigmurus.
Toxicon : official journal of the International Society on Toxinology 2009;54(4):379-89.
2009: Silva Edelyn C N; Camargos Thalita S; Maranhão Andrea Q; Silva-Pereira Ildinete; Silva Luciano P; Possani Lourival D; Schwartz Elisabeth F
Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum.
Toxicon : official journal of the International Society on Toxinology 2009;54(3):252-61.
2009: Hernández-Salgado Kenya; Estrada Georgina; Olvera Alejandro; Coronas Fredy I; Possani Lourival D; Corzo Gerardo
Heterologous expressed toxic and non-toxic peptide variants of toxin CssII are capable to produce neutralizing antibodies against the venom of the scorpion Centruroides suffusus suffusus.
Immunology letters 2009;125(2):93-9.
2009: D'Suze Gina; Schwartz Elisabeth F; García-Gómez B I; Sevcik Carlos; Possani Lourival D
Molecular cloning and nucleotide sequence analysis of genes from a cDNA library of the scorpion Tityus discrepans.
Biochimie 2009;91(8):1010-9.
2009: Corzo Gerardo; Bernard Cedric; Clement Herlinda; Villegas Elba; Bosmans Frank; Tytgat Jan; Possani Lourival D; Darbon Herve; Alagón Alejandro
Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2.
Biochimica et biophysica acta 2009;1794(8):1190-6.
2009: González-Morales Lidia; Diego-García Elia; Segovia Lorenzo; Gutiérrez Maria del Carmen; Possani Lourival D
Venom from the centipede Scolopendra viridis Say: purification, gene cloning and phylogenetic analysis of a phospholipase A2.
Toxicon : official journal of the International Society on Toxinology 2009;54(1):8-15.
2009: Schwartz Elisabeth F; Capes E Michelle; Diego-García Elia; Zamudio Fernando Z; Fuentes Oscar; Possani Lourival D; Valdivia Héctor H
Characterization of hadrucalcin, a peptide from Hadrurus gertschi scorpion venom with pharmacological activity on ryanodine receptors.
British journal of pharmacology 2009;157(3):392-403.
2009: García-Gómez Blanca I; Olamendi-Portugal Timoteo C; Paniagua Jorge; van der Walt Jurg; Dyason Karin; Possani Lourival D
Heterologous expression of a gene that codes for Pg8, a scorpion toxin of Parabuthus granulatus, capable of generating protecting antibodies in mice.
Toxicon : official journal of the International Society on Toxinology 2009;53(7-8):770-8.
2009: Prestipino Gianfranco; Corzo Gerardo; Romeo Stefania; Murgia Anna Rosa; Zanardi Ilaria; Gurrola Georgina B; Possani Lourival D
Scorpion toxins that block transient currents (I(A)) of rat cerebellum granular cells.
Toxicology letters 2009;187(1):1-9.
2009: Espino-Solis G P; Riaño-Umbarila L; Becerril B; Possani L D
Antidotes against venomous animals: state of the art and prospectives.
Journal of proteomics 2009;72(2):183-99.
2008: Petricevich V L; Reynaud E; Cruz A H; Possani L D
Macrophage activation, phagocytosis and intracellular calcium oscillations induced by scorpion toxins from Tityus serrulatus.
Clinical and experimental immunology 2008;154(3):415-23.
2008: Corzo Gerardo; Diego-García Elia; Clement Herlinda; Peigneur Steve; Odell George; Tytgat Jan; Possani Lourival D; Alagón Alejandro
An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.
Peptides 2008;29(11):1901-8.
2008: Corzo Gerardo; Papp Ferenc; Varga Zoltan; Barraza Omar; Espino-Solis Pavel G; Rodríguez de la Vega Ricardo C; Gaspar Rezso; Panyi Gyorgy; Possani Lourival D
A selective blocker of Kv1.2 and Kv1.3 potassium channels from the venom of the scorpion Centruroides suffusus suffusus.
Biochemical pharmacology 2008;76(9):1142-54.
2008: Abdel-Mottaleb Yousra; Corzo Gerardo; Martin-Eauclaire Marie-France; Satake Honoo; Céard Brigitte; Peigneur Steve; Nambaru Praveen; Bougis Pierre-Edouard; Possani Lourival D; Tytgat Jan
A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K+ channels.
Biochemical pharmacology 2008;76(6):805-15.
2008: Restano-Cassulini Rita; Olamendi-Portugal Timoteo; Zamudio Fernando; Becerril Baltazar; Possani Lourival Domingos
Two novel ergtoxins, blockers of K+-channels, purified from the Mexican scorpion Centruroides elegans elegans.
Neurochemical research 2008;33(8):1525-33.
2008: Schwartz Elisabeth F; Camargos Thalita S; Zamudio Fernando Z; Silva Luciano P; Bloch Carlos; Caixeta Fábio; Schwartz Carlos A; Possani Lourival D
Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum.
Toxicon : official journal of the International Society on Toxinology 2008;51(8):1499-508.
2008: Olamendi-Portugal Timoteo; Batista Cesar V F; Restano-Cassulini Rita; Pando Victoria; Villa-Hernandez Oscar; Zavaleta-Martínez-Vargas Alfonso; Salas-Arruz Maria C; Rodríguez de la Vega Ricardo C; Becerril Baltazar; Possani Lourival D
Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.
Proteomics 2008;8(9):1919-32.
2008: Romeo Stefania; Corzo Gerardo; Vasile Attilio; Satake Honoo; Prestipino Gianfranco; Possani Lourival D
A positive charge at the N-terminal segment of Discrepin increases the blocking effect of K+ channels responsible for the IA currents in cerebellum granular cells.
Biochimica et biophysica acta 2008;1780(4):750-5.
2008: Espino-Solis Gerardo P; Osuna-Quintero Joel; Possani Lourival D
Molecular cloning and characterization of the alphaX subunit from CD11c/CD18 horse integrin.
Veterinary immunology and immunopathology 2008;122(3-4):326-34.
2008: Diego-García E; Abdel-Mottaleb Y; Schwartz E F; de la Vega R C Rodríguez; Tytgat J; Possani L D
Cytolytic and K+ channel blocking activities of beta-KTx and scorpine-like peptides purified from scorpion venoms.
Cellular and molecular life sciences : CMLS 2008;65(1):187-200.
2007: Petricevich Vera L; Hernández Cruz Anselmo; Coronas Fredy I V; Possani Lourival D
Toxin gamma from Tityus serrulatus scorpion venom plays an essential role in immunomodulation of macrophages.
Toxicon : official journal of the International Society on Toxinology 2007;50(5):666-75.
2007: López-Vera Estuardo; Aguilar Manuel B; Schiavon Emanuele; Marinzi Chiara; Ortiz Ernesto; Restano Cassulini Rita; Batista Cesar V F; Possani Lourival D; Heimer de la Cotera Edgar P; Peri Francesco; Becerril Baltazar; Wanke Enzo
Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.
The FEBS journal 2007;274(15):3972-85.
2007: Estrada Georgina; Garcia Blanca I; Schiavon Emanuele; Ortiz Ernesto; Cestele Sandrine; Wanke Enzo; Possani Lourival D; Corzo Gerardo
Four disulfide-bridged scorpion beta neurotoxin CssII: heterologous expression and proper folding in vitro.
Biochimica et biophysica acta 2007;1770(8):1161-8.
2007: Valdez-Cruz Norma A; Segovia Lorenzo; Corona Miguel; Possani Lourival D
Sequence analysis and phylogenetic relationship of genes encoding heterodimeric phospholipases A2 from the venom of the scorpion Anuroctonus phaiodactylus.
Gene 2007;396(1):149-58.
2007: Clement Herlinda; Odell George; Zamudio Fernando Z; Redaelli Elisa; Wanke Enzo; Alagón Alejandro; Possani Lourival D
Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels.
Toxicon : official journal of the International Society on Toxinology 2007;50(1):65-74.
2007: Batista C V F; Román-González S A; Salas-Castillo S P; Zamudio F Z; Gómez-Lagunas F; Possani L D
Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2007;146(1-2):147-57.
2007: de la Vega Ricardo C Rodríguez; Possani Lourival D
Novel paradigms on scorpion toxins that affects the activating mechanism of sodium channels.
Toxicon : official journal of the International Society on Toxinology 2007;49(2):171-80.
2007: Quintero-Hernández Veronica; Juárez-González Victor R; Ortíz-León Mauricio; Sánchez Rosalba; Possani Lourival D; Becerril Baltazar
The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies.
Molecular immunology 2007;44(6):1307-15.
2007: Diego-García Elia; Schwartz Elisabeth F; D'Suze Gina; González Sergio A Román; Batista Cesar V F; García Blanca I; de la Vega Ricardo C Rodríguez; Possani Lourival D
Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components.
Peptides 2007;28(1):31-7.
2007: Schwartz Elisabeth F; Diego-Garcia Elia; Rodríguez de la Vega Ricardo C; Possani Lourival D
Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones).
BMC genomics 2007;8():119.
2006: Schwartz Elisabeth F; Schwartz Carlos A; Gómez-Lagunas Froylan; Zamudio Fernando Z; Possani Lourival D
HgeTx1, the first K+-channel specific toxin characterized from the venom of the scorpion Hadrurus gertschi Soleglad.
Toxicon : official journal of the International Society on Toxinology 2006;48(8):1046-53.
2006: Caliskan Figen; García Blanca Ines; Coronas Fredy I V; Batista Cesar V F; Zamudio Fernando Z; Possani Lourival D
Characterization of venom components from the scorpion Androctonus crassicauda of Turkey: peptides and genes.
Toxicon : official journal of the International Society on Toxinology 2006;48(1):12-22.
2006: Schiavon Emanuele; Sacco Tiziana; Cassulini Rita Restano; Gurrola Georgina; Tempia Filippo; Possani Lourival D; Wanke Enzo
Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons.
The Journal of biological chemistry 2006;281(29):20326-37.
2006: Batista Cesar V F; D'Suze Gina; Gómez-Lagunas Froylan; Zamudio Fernando Z; Encarnación Sergio; Sevcik Carlos; Possani Lourival D
Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins.
Proteomics 2006;6(12):3718-27.
2006: Mebs Dietrich; Kuch Ulrich; Coronas Fredy I V; Batista Cesar V F; Gumprecht Andreas; Possani Lourival D
Biochemical and biological activities of the venom of the Chinese pitviper Zhaoermia mangshanensis, with the complete amino acid sequence and phylogenetic analysis of a novel Arg49 phospholipase A2 myotoxin.
Toxicon : official journal of the International Society on Toxinology 2006;47(7):797-811.
2006: Restano-Cassulini Rita; Korolkova Yuliya V; Diochot Sylvie; Gurrola Georgina; Guasti Leonardo; Possani Lourival D; Lazdunski Michel; Grishin Eugene V; Arcangeli Annarosa; Wanke Enzo
Species diversity and peptide toxins blocking selectivity of ether-a-go-go-related gene subfamily K+ channels in the central nervous system.
Molecular pharmacology 2006;69(5):1673-83.
2006: Prochnicka-Chalufour Ada; Corzo Gerardo; Satake Honoo; Martin-Eauclaire Marie-France; Murgia Anna Rosa; Prestipino Gianfranco; D'Suze Gina; Possani Lourival D; Delepierre Muriel
Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily.
Biochemistry 2006;45(6):1795-804.
2006: Abdel-Mottaleb Yousra; Coronas Fredy V; de Roodt Adolfo R; Possani Lourival D; Tytgat Jan
A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily.
FEBS letters 2006;580(2):592-6.
2006: Barona Jacqueline; Batista Cesar V F; Zamudio Fernando Z; Gomez-Lagunas Froylan; Wanke Enzo; Otero Rafael; Possani Lourival D
Proteomic analysis of the venom and characterization of toxins specific for Na+ - and K+ -channels from the Colombian scorpion Tityus pachyurus.
Biochimica et biophysica acta 2006;1764(1):76-84.
2006: Panyi G; Possani L D; Rodríguez de la Vega R C; Gáspár R; Varga Z
K+ channel blockers: novel tools to inhibit T cell activation leading to specific immunosuppression.
Current pharmaceutical design 2006;12(18):2199-220.
2005: Rodríguez de la Vega Ricardo C; Possani Lourival D
Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution.
Toxicon : official journal of the International Society on Toxinology 2005;46(8):831-44.
2005: Olamendi-Portugal Timoteo; Somodi Sándor; Fernández Juan Antonio; Zamudio Fernando Z; Becerril Baltazar; Varga Zoltán; Panyi Gyorgy; Gáspár Rezso; Possani Lourival D
Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockade Kv1.3 over IKCa1 K+ channels of T cells.
Toxicon : official journal of the International Society on Toxinology 2005;46(4):418-29.
2005: Aguilar Manuel B; López-Vera Estuardo; Ortiz Ernesto; Becerril Baltazar; Possani Lourival D; Olivera Baldomero M; Heimer de la Cotera Edgar P
A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues.
Biochemistry 2005;44(33):11130-6.
2005: Padilla Alejandro; Govezensky Tzipe; Possani Lourival D; Larralde Carlos
Mortality and antibody responses of mice to three successive episodes of experimental scorpion (Centruroides limpidus limpidus) envenomation and immunological rescue.
Toxicon : official journal of the International Society on Toxinology 2005;46(2):142-9.
2005: Rodríguez de la Vega Ricardo C; Possani Lourival D
On the evolution of invertebrate defensins.
Trends in genetics : TIG 2005;21(6):330-2.
2005: Riaño-Umbarila Lidia; Juárez-González Victor Rivelino; Olamendi-Portugal Timoteo; Ortíz-León Mauricio; Possani Lourival Domingos; Becerril Baltazar
A strategy for the generation of specific human antibodies by directed evolution and phage display. An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom.
The FEBS journal 2005;272(10):2591-601.
2005: Gazarian Karlen G; Gazarian Tatiana; Hernández Ricardo; Possani Lourival D
Immunology of scorpion toxins and perspectives for generation of anti-venom vaccines.
Vaccine 2005;23(26):3357-68.
2005: Bagdány Miklós; Batista Cesar V F; Valdez-Cruz Norma A; Somodi Sándor; Rodriguez de la Vega Ricardo C; Licea Alexei F; Varga Zoltán; Gáspár Rezso; Possani Lourival D; Panyi György
Anuroctoxin, a new scorpion toxin of the alpha-KTx 6 subfamily, is highly selective for Kv1.3 over IKCa1 ion channels of human T lymphocytes.
Molecular pharmacology 2005;67(4):1034-44.
2005: Juárez-González V R; Riaño-Umbarila L; Quintero-Hernández V; Olamendi-Portugal T; Ortiz-León M; Ortíz E; Possani L D; Becerril B
Directed evolution, phage display and combination of evolved mutants: a strategy to recover the neutralization properties of the scFv version of BCF2 a neutralizing monoclonal antibody specific to scorpion toxin Cn2.
Journal of molecular biology 2005;346(5):1287-97.
2005: Diego-García Elia; Batista Cesar V F; García-Gómez Blanca I; Lucas Sylvia; Candido Denise M; Gómez-Lagunas Froylan; Possani Lourival D
The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function.
Toxicon : official journal of the International Society on Toxinology 2005;45(3):273-83.
2004: Valdez-Cruz Norma A; Batista Cesar V F; Zamudio Fernando Z; Bosmans Frank; Tytgat Jan; Possani Lourival D
Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus.
European journal of biochemistry / FEBS 2004;271(23-24):4753-61.
2004: D'Suze Gina; Batista Cesar V F; Frau Andrea; Murgia Anna Rosa; Zamudio Fernando Z; Sevcik Carlos; Possani Lourival D; Prestipino Gianfranco
Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+ -channels (IA currents) of cerebellum granular cells.
Archives of biochemistry and biophysics 2004;430(2):256-63.
2004: Frénal Karine; Xu Chen-Qi; Wolff Nicolas; Wecker Karine; Gurrola Georgina B; Zhu Shun-Yi; Chi Cheng-Wu; Possani Lourival D; Tytgat Jan; Delepierre Muriel
Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels.
Proteins 2004;56(2):367-75.
2004: Valdez-Cruz Norma A; Dávila Sonia; Licea Alexei; Corona Miguel; Zamudio Fernando Z; García-Valdes Jesús; Boyer Leslie; Possani Lourival D
Biochemical, genetic and physiological characterization of venom components from two species of scorpions: Centruroides exilicauda Wood and Centruroides sculpturatus Ewing.
Biochimie 2004;86(6):387-96.
2004: Rodríguez de la Vega Ricardo C; Possani Lourival D
Current views on scorpion toxins specific for K+-channels.
Toxicon : official journal of the International Society on Toxinology 2004;43(8):865-75.
2004: Rodríguez de la Vega R C; García B I; D'Ambrosio C; Diego-García E; Scaloni A; Possani L D
Antimicrobial peptide induction in the haemolymph of the Mexican scorpion Centruroides limpidus limpidus in response to septic injury.
Cellular and molecular life sciences : CMLS 2004;61(12):1507-19.
2004: del Río-Portilla Federico; Hernández-Marín Elizabeth; Pimienta Genaro; Coronas Fredy V; Zamudio Fernando Z; Rodríguez de la Vega Ricardo C; Wanke Enzo; Possani Lourival D
NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity.
European journal of biochemistry / FEBS 2004;271(12):2504-16.
2004: Zhu Xinsheng; Zamudio Fernando Z; Olbinski Beth A; Possani Lourival D; Valdivia Héctor H
Activation of skeletal ryanodine receptors by two novel scorpion toxins from Buthotus judaicus.
The Journal of biological chemistry 2004;279(25):26588-96.
2004: Murgia Anna Rosa; Batista Cesar V F; Prestipino Gianfranco; Possani Lourival D
Amino acid sequence and function of a new alpha-toxin from the Amazonian scorpion Tityus cambridgei.
Toxicon : official journal of the International Society on Toxinology 2004;43(6):737-40.
2004: Valdez-Cruz Norma A; Batista Cesar V F; Possani Lourival D
Phaiodactylipin, a glycosylated heterodimeric phospholipase A from the venom of the scorpion Anuroctonus phaiodactylus.
European journal of biochemistry / FEBS 2004;271(8):1453-64.
2004: Batista Cesar V F; del Pozo Luis; Zamudio Fernando Z; Contreras Sandra; Becerril Baltazar; Wanke Enzo; Possani Lourival D
Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;803(1):55-66.
2004: D'Suze G; Sevcik C; Corona M; Zamudio F Z; Batista C V F; Coronas F I; Possani L D
Ardiscretin a novel arthropod-selective toxin from Tityus discrepans scorpion venom.
Toxicon : official journal of the International Society on Toxinology 2004;43(3):263-72.
2004: Gómez-Lagunas Froylan; Batista Cesar V F; Olamendi-Portugal Timoteo; Ramírez-Domínguez Martha E; Possani Lourival D
Inhibition of the collapse of the Shaker K+ conductance by specific scorpion toxins.
The Journal of general physiology 2004;123(3):265-79.
2004: Selisko Barbara; Cosío Gabriela; García Consuelo; Becerril Baltazar; Possani Lourival D; Horjales Eduardo
Bacterial expression, purification and functional characterization of a recombinant chimeric Fab derived from murine mAb BCF2 that neutralizes the venom of the scorpion Centruroides noxius hoffmann.
Toxicon : official journal of the International Society on Toxinology 2004;43(1):43-51.
2004: Pascual Isel; Gil-Parrado Shirley; Cisneros Miguel; Joseph-Bravo Patricia; Díaz Joaquín; Possani Lourival D; Charli Jean Louis; Chávez María
Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. in vivo effects in rodent brain.
The international journal of biochemistry & cell biology 2004;36(1):138-52.
2004: Shalabi Andree; Zamudio Fernando; Wu Xiaoyan; Scaloni Andrea; Possani Lourival D; Villereal Mitchel L
Tetrapandins, a new class of scorpion toxins that specifically inhibit store-operated calcium entry in human embryonic kidney-293 cells.
The Journal of biological chemistry 2004;279(2):1040-9.
2004: Huys Isabelle; Olamendi-Portugal Timoteo; Garcia-Gómez Blanca Ines; Vandenberghe Isabel; Van Beeumen Jozef; Dyason Karin; Clynen Elke; Zhu Shunyi; van der Walt Jurg; Possani Lourival D; Tytgat Jan
A subfamily of acidic alpha-K(+) toxins.
The Journal of biological chemistry 2004;279(4):2781-9.
2003: Guijarro J Iñaki; M'Barek Sarrah; Gómez-Lagunas Froylan; Garnier Damien; Rochat Hervé; Sabatier Jean-Marc; Possani Lourival; Delepierre Muriel;
Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels.
Protein science : a publication of the Protein Society 2003;12(9):1844-54.
2003: Guijarro J Iñaki; M'Barek Sarrah; Gómez-Lagunas Froylan; Garnier Damien; Rochat Hervé; Sabatier Jean-Marc; Possani Lourival; Delepierre Muriel;
Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels.
Protein science : a publication of the Protein Society 2003;12(9):1844-54.
2003: Coronas F V; Stankiewicz M; Batista C V F; Giraud S; Alam J M; Possani L D; Mebs D; Pelhate M
Primary structure and electrophysiological characterization of two almost identical isoforms of toxin from Isometrus vittatus (family: Buthidae) scorpion venom.
Toxicon : official journal of the International Society on Toxinology 2003;41(8):989-97.
2003: Padilla Alejandro; Govezensky Tzipe; Possani Lourival D; Larralde Carlos
Experimental envenoming of mice with venom from the scorpion Centruroides limpidus limpidus: differences in mortality and symptoms with and without antibody therapy relating to differences in age, sex and strain of mouse.
Toxicon : official journal of the International Society on Toxinology 2003;41(8):959-65.
2003: Gutiérrez María del Carmen; Abarca Carolina; Possani Lourival D
A toxic fraction from scolopendra venom increases the basal release of neurotransmitters in the ventral ganglia of crustaceans.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2003;135(2):205-14.
2003: Corona Miguel; Coronas Fredy V; Merino Enrique; Becerril Baltazar; Gutiérrez Rafael; Rebolledo-Antunez Santiago; Garcia David E; Possani Lourival D
A novel class of peptide found in scorpion venom with neurodepressant effects in peripheral and central nervous system of the rat.
Biochimica et biophysica acta 2003;1649(1):58-67.
2003: Rodríguez de la Vega Ricardo C; Merino Enrique; Becerril Baltazar; Possani Lourival D
Novel interactions between K+ channels and scorpion toxins.
Trends in pharmacological sciences 2003;24(5):222-7.
2003: Possani Lourival D
The past, present, and future of biotechnology in Mexico.
Nature biotechnology 2003;21(5):582-3.
2003: Gazarian Tatiana G; Selisko Barbara; Gurrola Georgina B; Hernández Ricardo; Possani Lourival D; Gazarian Karlen G
Potential of peptides selected from random phage-displayed libraries to mimic conformational epitopes: a study on scorpion toxin Cn2 and the neutralizing monoclonal antibody BCF2.
Combinatorial chemistry & high throughput screening 2003;6(2):119-32.
2003: Garcia Consuelo; Calderón-Aranda Emma S; Anguiano Gerardo A V; Becerril Baltazar; Possani Lourival D
Analysis of the immune response induced by a scorpion venom sub-fraction, a pure peptide and a recombinant peptide, against toxin Cn2 of Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 2003;41(4):417-27.
2003: Coronas Fredy V; de Roodt Adolfo R; Portugal Timoteo Olamendi; Zamudio Fernando Z; Batista Cesar V F; Gómez-Lagunas Froylan; Possani Lourival D
Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus.
Toxicon : official journal of the International Society on Toxinology 2003;41(2):173-9.
2003: López-González Ignacio; Olamendi-Portugal Timoteo; De la Vega-Beltrán José L; Van der Walt Jurg; Dyason Karin; Possani Lourival D; Felix Ricardo; Darszon Alberto
Scorpion toxins that block T-type Ca2+ channels in spermatogenic cells inhibit the sperm acrosome reaction.
Biochemical and biophysical research communications 2003;300(2):408-14.
2002: Vacher Hélène; Alami Meriem; Crest Marcel; Possani Lourival D; Bougis Pierre E; Martin-Eauclaire Marie-France
Expanding the scorpion toxin alpha-KTX 15 family with AmmTX3 from Androctonus mauretanicus.
European journal of biochemistry / FEBS 2002;269(24):6037-41.
2002: Corona Miguel; Gurrola Georgina B; Merino Enrique; Cassulini Rita Restano; Valdez-Cruz Norma A; García Blanca; Ramírez-Domínguez Martha E; Coronas Fredy I V; Zamudio Fernando Z; Wanke Enzo; Possani Lourival D
A large number of novel Ergtoxin-like genes and ERG K+-channels blocking peptides from scorpions of the genus Centruroides.
FEBS letters 2002;532(1-2):121-6.
2002: Olamendi-Portugal Timoteo; García Blanca Inés; López-González Ignacio; Van Der Walt Jurg; Dyason Karin; Ulens Chris; Tytgat Jan; Felix Ricardo; Darszon Alberto; Possani Lourival D
Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels.
Biochemical and biophysical research communications 2002;299(4):562-8.
2002: Batista Cesar V F; Gómez-Lagunas Froylan; Rodríguez de la Vega Ricardo C; Hajdu Péter; Panyi György; Gáspár Rezsõ; Possani Lourival D
Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities.
Biochimica et biophysica acta 2002;1601(2):123-31.
2002: Angulo Yamileth; Olamendi-Portugal Timoteo; Alape-Girón Alberto; Possani Lourival D; Lomonte Bruno
Structural characterization and phylogenetic relationships of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a Lys49 phospholipase A(2) homologue.
The international journal of biochemistry & cell biology 2002;34(10):1268-78.
2002: Possani Lourival D; Corona Miguel; Zurita Mario; Rodríguez Mario H
From noxiustoxin to scorpine and possible transgenic mosquitoes resistant to malaria.
Archives of medical research 2002;33(4):398-404.
2002: Corzo Gerardo; Villegas Elba; Gómez-Lagunas Froylan; Possani Lourival D; Belokoneva Olga S; Nakajima Terumi
Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins.
The Journal of biological chemistry 2002;277(26):23627-37.
2002: Lecchi Marzia; Redaelli Elisa; Rosati Barbara; Gurrola Georgina; Florio Tullio; Crociani Olivia; Curia Giulia; Cassulini Rita Restano; Masi Alessio; Arcangeli Annarosa; Olivotto Massimo; Schettini Gennaro; Possani Lourival D; Wanke Enzo
Isolation of a long-lasting eag-related gene-type K+ current in MMQ lactotrophs and its accommodating role during slow firing and prolactin release.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(9):3414-25.
2002: Pardo-Lopez Liliana; Zhang Mei; Liu Jie; Jiang Min; Possani Lourival D; Tseng Gea-Ny
Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule.
The Journal of biological chemistry 2002;277(19):16403-11.
2002: Batista Cesar V F; Zamudio Fernando Z; Lucas Sylvia; Fox Jay W; Frau Andrea; Prestipino Gianfranco; Possani Lourival D
Scorpion toxins from Tityus cambridgei that affect Na(+)-channels.
Toxicon : official journal of the International Society on Toxinology 2002;40(5):557-62.
2002: Ramirez-Dominguez Martha E; Olamendi-Portugal Timoteo; Garcia Ubaldo; Garcia Consuelo; Arechiga Hugo; Possani Lourival D
Cn11, the first example of a scorpion toxin that is a true blocker of Na(+) currents in crayfish neurons.
The Journal of experimental biology 2002;205(Pt 6):869-76.
2002: Pardo-López Liliana; García-Valdés Jesús; Gurrola Georgina B; Robertson Gail A; Possani Lourival D
Mapping the receptor site for ergtoxin, a specific blocker of ERG channels.
FEBS letters 2002;510(1-2):45-9.
2001: Corona M; Valdez-Cruz N A; Merino E; Zurita M; Possani L D
Genes and peptides from the scorpion Centruroides sculpturatus Ewing, that recognize Na(+)-channels.
Toxicon : official journal of the International Society on Toxinology 2001;39(12):1893-8.
2001: Goudet C; Ferrer T; Galàn L; Artiles A; Batista C F; Possani L D; Alvarez J; Aneiros A; Tytgat J
Characterization of two Bunodosoma granulifera toxins active on cardiac sodium channels.
British journal of pharmacology 2001;134(6):1195-206.
2001: Garcia-Valdes J; Zamudio F Z; Toro L; Possani L D;
Slotoxin, alphaKTx1.11, a new scorpion peptide blocker of MaxiK channels that differentiates between alpha and alpha+beta (beta1 or beta4) complexes.
FEBS letters 2001;505(3):369-73.
2001: Rocchetti M; Besana A; Gurrola G B; Possani L D; Zaza A
Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential.
The Journal of physiology 2001;534(Pt 3):721-32.
2001: Péter M; Varga Z; Hajdu P; Gáspár R; Damjanovich S; Horjales E; Possani L D; Panyi G
Effects of toxins Pi2 and Pi3 on human T lymphocyte Kv1.3 channels: the role of Glu7 and Lys24.
The Journal of membrane biology 2001;179(1):13-25.
2001: Frau A; Pisciotta M; Gurrola G B; Possani L D; Prestipino G
Synthetic undecapeptide (NTX10-20) of noxiustoxin blocks completely the I(A) potassium currents of cerebellum granular cells.
European biophysics journal : EBJ 2001;29(8):569-73.
2000: Batista C V; Gómez-Lagunas F; Lucas S; Possani L D
Tc1, from Tityus cambridgei, is the first member of a new subfamily of scorpion toxin that blocks K(+)-channels.
FEBS letters 2000;486(2):117-20.
2000: Péter M; Hajdu P; Varga Z; Damjanovich S; Possani L D; Panyi G; Gáspár R
Blockage of human T lymphocyte Kv1.3 channels by Pi1, a novel class of scorpion toxin.
Biochemical and biophysical research communications 2000;278(1):34-7.
2000: Possani L D; Merino E; Corona M; Bolivar F; Becerril B
Peptides and genes coding for scorpion toxins that affect ion-channels.
Biochimie 2000;82(9-10):861-8.
2000: Pisciotta M; Coronas F I; Bloch C; Prestipino G; Possani L D
Fast K(+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom.
Biochimica et biophysica acta 2000;1468(1-2):203-12.
2000: Scaloni A; Bottiglieri C; Ferrara L; Corona M; Gurrola G B; Batista C; Wanke E; Possani L D
Disulfide bridges of ergtoxin, a member of a new sub-family of peptide blockers of the ether-a-go-go-related K+ channel.
FEBS letters 2000;479(3):156-7.
2000: Torres-Larios A; Gurrola G B; Zamudio F Z; Possani L D
Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus.
European journal of biochemistry / FEBS 2000;267(16):5023-31.
2000: Conde R; Zamudio F Z; Rodríguez M H; Possani L D
Scorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom.
FEBS letters 2000;471(2-3):165-8.
2000: Angulo Y; Olamendi-Portugal T; Possani L D; Lomonte B
Isolation and characterization of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a new Lys49 phospholipase A2 homologue.
The international journal of biochemistry & cell biology 2000;32(1):63-71.
1999: Delepierre M; Prochnicka-Chalufour A; Boisbouvier J; Possani L D
Pi7, an orphan peptide from the scorpion Pandinus imperator: a 1H-NMR analysis using a nano-NMR Probe.
Biochemistry 1999;38(51):16756-65.
1999: Conde R; Zamudio F Z; Becerril B; Possani L D
Phospholipin, a novel heterodimeric phospholipase A2 from Pandinus imperator scp6pion venom.
FEBS letters 1999;460(3):447-50.
1999: Tytgat J; Chandy K G; Garcia M L; Gutman G A; Martin-Eauclaire M F; van der Walt J J; Possani L D
A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies.
Trends in pharmacological sciences 1999;20(11):444-7.
1999: Selisko B; Licea A F; Becerril B; Zamudio F; Possani L D; Horjales E
Antibody BCF2 against scorpion toxin Cn2 from Centuroides noxius Hoffmann: primary structure and three-dimensional model as free Fv fragment and complexed with its antigen.
Proteins 1999;37(1):130-43.
1999: Calderon-Aranda E S; Selisko B; York E J; Gurrola G B; Stewart J M; Possani L D
Mapping of an epitope recognized by a neutralizing monoclonal antibody specific to toxin Cn2 from the scorpion Centruroides noxius, using discontinuous synthetic peptides.
European journal of biochemistry / FEBS 1999;264(3):746-55.
1999: Possani L D; Becerril B; Delepierre M; Tytgat J
Scorpion toxins specific for Na+-channels.
European journal of biochemistry / FEBS 1999;264(2):287-300.
1999: D'Suze G; Zamudio F; Gómez-Lagunas F; Possani L D
A novel K+ channel blocking toxin from Tityus discrepans scorpion venom.
FEBS letters 1999;456(1):146-8.
1999: Gurrola G B; Rosati B; Rocchetti M; Pimienta G; Zaza A; Arcangeli A; Olivotto M; Possani L D; Wanke E
A toxin to nervous, cardiac, and endocrine ERG K+ channels isolated from Centruroides noxius scorpion venom.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):953-62.
1999: Pintar A; Possani L D; Delepierre M
Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels.
Journal of molecular biology 1999;287(2):359-67.
1999: Ottolia M; Babini E; Gazzotti P; Possani L D; Prestipino G
Reconstitution of a voltage and calcium dependent potassium channel from rat cerebellum.
Brain research 1999;815(2):410-3.
1999: Batista C V; da Silva L R; Sebben A; Scaloni A; Ferrara L; Paiva G R; Olamendi-Portugal T; Possani L D; Bloch C
Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta.
Peptides 1999;20(6):679-86.
1998: Tytgat J; Debont T; Rostoll K; Müller G J; Verdonck F; Daenens P; van der Walt J J; Possani L D
Purification and partial characterization of a 'short' insectotoxin-like peptide from the venom of the scorpion Parabuthus schlechteri.
FEBS letters 1998;441(3):387-91.
1998: Possani L D; Zurita M; Delepierre M; Hernández F H; Rodríguez M H
From noxiustoxin to Shiva-3, a peptide toxic to the sporogonic development of Plasmodium berghei.
Toxicon : official journal of the International Society on Toxinology 1998;36(11):1683-92.
1998: Delepierre M; Prochnicka-Chalufour A; Possani L D
1H NMR structural analysis of novel potassium blocking toxins using a nano-NMR probe.
Toxicon : official journal of the International Society on Toxinology 1998;36(11):1599-608.
1998: Boisbouvier J; Prochnicka-Chalufour A; Nieto A R; Torres J A; Nanard N; Rodriguez M H; Possani L D; Delepierre M
Structural information on a cecropin-like synthetic peptide, Shiva-3 toxic to the sporogonic development of Plasmodium berghei.
European journal of biochemistry / FEBS 1998;257(1):263-73.
1998: Selisko B; Garcia C; Becerril B; Gómez-Lagunas F; Garay C; Possani L D
Cobatoxins 1 and 2 from Centruroides noxius Hoffmann constitute a subfamily of potassium-channel-blocking scorpion toxins.
European journal of biochemistry / FEBS 1998;254(3):468-79.
1998: Martínez F; Muñoz-Garay C; Gurrola G; Darszon A; Possani L D; Becerril B
Site directed mutants of Noxiustoxin reveal specific interactions with potassium channels.
FEBS letters 1998;429(3):381-4.
1998: Olamendi-Portugal T; Gómez-Lagunas F; Gurrola G B; Possani L D
Two similar peptides from the venom of the scorpion Pandinus imperator, one highly effective blocker and the other inactive on K+ channels.
Toxicon : official journal of the International Society on Toxinology 1998;36(5):759-70.
1998: Péter M; Varga Z; Panyi G; Bene L; Damjanovich S; Pieri C; Possani L D; Gáspár R
Pandinus imperator scorpion venom blocks voltage-gated K+ channels in human lymphocytes.
Biochemical and biophysical research communications 1998;242(3):621-5.
1998: Pisciotta M; Ottolia M; Possani L D; Prestipino G
A novel toxin form the scorpion Androctonus australis blocks Shaker K+ channels expressed in Xenopus oocytes.
Biochemical and biophysical research communications 1998;242(2):287-91.
1998: Pisciotta M; Coronas F I; Possani L D; Prestipino G
The Androctonus australis garzoni scorpion venom contains toxins that selectively affect voltage-dependent K(+)-channels in cerebellum granular cells.
European biophysics journal : EBJ 1998;27(1):69-73.
1997: Ben Khalifa R; Stankiewicz M; Pelhate M; Serrano-Hernandez S E; Possani L D; Hinkel H; Mebs D
Action of babycurus-toxin 1 from the east African scorpion Babycurus centrurimorphus on the isolated cockroach giant axon.
Toxicon : official journal of the International Society on Toxinology 1997;35(7):1069-80.
1997: Becerril B; Marangoni S; Possani L D
Toxins and genes isolated from scorpions of the genus Tityus.
Toxicon : official journal of the International Society on Toxinology 1997;35(6):821-35.
1997: Zamudio F Z; Conde R; Arévalo C; Becerril B; Martin B M; Valdivia H H; Possani L D
The mechanism of inhibition of ryanodine receptor channels by imperatoxin I, a heterodimeric protein from the scorpion Pandinus imperator.
The Journal of biological chemistry 1997;272(18):11886-94.
1997: Zamudio F Z; Gurrola G B; Arévalo C; Sreekumar R; Walker J W; Valdivia H H; Possani L D
Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors.
FEBS letters 1997;405(3):385-9.
1997: García C; Becerril B; Selisko B; Delepierre M; Possani L D
Isolation, characterization and comparison of a novel crustacean toxin with a mammalian toxin from the venom of the scorpion Centruroides noxius Hoffmann.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1997;116(3):315-22.
1997: Delepierre M; Prochnicka-Chalufour A; Possani L D
A novel potassium channel blocking toxin from the scorpion Pandinus imperator: A 1H NMR analysis using a nano-NMR probe.
Biochemistry 1997;36(9):2649-58.
1997: Gómez-Lagunas F; Olamendi-Portugal T; Possani L D
Block of ShakerB K+ channels by Pi1, a novel class of scorpion toxin.
FEBS letters 1997;400(2):197-200.
1996: Selisko B; Garcia C; Becerril B; Delepierre M; Possani L D
An insect-specific toxin from Centruroides noxius Hoffmann. cDNA, primary structure, three-dimensional model and electrostatic surface potentials in comparison with other toxin variants.
European journal of biochemistry / FEBS 1996;242(2):235-42.
1996: Martinez F; Becerril B; Gurrola G B; Martin B M; Possani L D
Synthesis and expression of the gene coding for noxiustoxin, a K+ channel-blocking peptide from the venom of the scorpion Centruroides noxius.
Toxicon : official journal of the International Society on Toxinology 1996;34(11-12):1413-9.
1996: Nieto A R; Gurrola G B; Vaca L; Possani L D
Noxiustoxin 2, a novel K+ channel blocking peptide from the venom of the scorpion Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1996;34(8):913-22.
1996: Licea A F; Becerril B; Possani L D
Fab fragments of the monoclonal antibody BCF2 are capable of neutralizing the whole soluble venom from the scorpion Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1996;34(8):843-7.
1996: Gómez-Lagunas F; Olamendi-Portugal T; Zamudio F Z; Possani L D
Two novel toxins from the venom of the scorpion Pandinus imperator show that the N-terminal amino acid sequence is important for their affinities towards Shaker B K+ channels.
The Journal of membrane biology 1996;152(1):49-56.
1996: Nobile M; Noceti F; Prestipino G; Possani L D
Helothermine, a lizard venom toxin, inhibits calcium current in cerebellar granules.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1996;110(1):15-20.
1996: Zamudio F; Wolf K M; Martin B M; Possani L D; Chiappinelli V A
Two novel alpha-neurotoxins isolated from the taipan snake, Oxyuranus scutellatus, exhibit reduced affinity for nicotinic acetylcholine receptors in brain and skeletal muscle.
Biochemistry 1996;35(24):7910-6.
1996: D'Suze G; Corona F; Possani L D; Sevcik C
High performance liquid chromatography purification and amino acid sequence of toxins from the muscarinic fraction of Tityus discrepans scorpion venom.
Toxicon : official journal of the International Society on Toxinology 1996;34(5):591-8.
1996: Olamendi-Portugal T; Gómez-Lagunas F; Gurrola G B; Possani L D
A novel structural class of K+-channel blocking toxin from the scorpion Pandinus imperator.
The Biochemical journal 1996;315 ( Pt 3)():977-81.
1996: Vaca L; Licea A; Possani L D
Modulation of cell membrane potential in cultured vascular endothelium.
The American journal of physiology 1996;270(3 Pt 1):C819-24.
1996: Corona M; Zurita M; Possani L D; Becerril B
Cloning and characterization of the genomic region encoding toxin IV-5 from the scorpion Tityus serrulatus Lutz and Mello.
Toxicon : official journal of the International Society on Toxinology 1996;34(2):251-6.
1996: Dehesa-Dávila M; Ramírez A N; Zamudio F Z; Gurrola-Briones G; Liévano A; Darszon A; Possani L D
Structural and functional comparison of toxins from the venom of the scorpions Centruroides infamatus infamatus, Centruroides limpidus limpidus and Centruroides noxius.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1996;113(2):331-9.
1996: Becerril B; Corona M; Coronas F I; Zamudio F; Calderon-Aranda E S; Fletcher P L; Martin B M; Possani L D
Toxic peptides and genes encoding toxin gamma of the Brazilian scorpions Tityus bahiensis and Tityus stigmurus.
The Biochemical journal 1996;313 ( Pt 3)():753-60.
1995: Dauplais M; Gilquin B; Possani L D; Gurrola-Briones G; Roumestand C; Ménez A
Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins.
Biochemistry 1995;34(51):16563-73.
1995: Gurrola G B; Possani L D
Structural and functional features of noxiustoxin: a K+ channel blocker.
Biochemistry and molecular biology international 1995;37(3):527-35.
1995: Noceti F; Ramírez A N; Possani L D; Prestipino G
Characterization of a voltage-dependent potassium channel in squid Schwann cells reconstituted in planar lipid bilayers.
Glia 1995;15(1):33-42.
1995: Vazquez A; Tapia J V; Eliason W K; Martin B M; Lebreton F; Delepierre M; Possani L D; Becerril B
Cloning and characterization of the cDNAs encoding Na+ channel-specific toxins 1 and 2 of the scorpion Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1995;33(9):1161-70.
1995: Calderon-Aranda E S; Olamendi-Portugal T; Possani L D
The use of synthetic peptides can be a misleading approach to generate vaccines against scorpion toxins.
Vaccine 1995;13(13):1198-206.
1995: Gáspár R; Bene L; Damjanovich S; Muñoz-Garay C; Calderon-Aranda E S; Possani L D
Beta-scorpion toxin 2 from Centruroides noxius blocks voltage-gated K+ channels in human lymphocytes.
Biochemical and biophysical research communications 1995;213(2):419-23.
1995: Hérion P; Gurrola-Briones G; Del Rocío Sánchez M; Saavedra R; Possani L D
Monoclonal antibodies against noxiustoxin.
Hybridoma 1995;14(3):247-51.
1994: Dehesa-Dávila M; Martin B M; Nobile M; Prestipino G; Possani L D
Isolation of a toxin from Centruroides infamatus infamatus Koch scorpion venom that modifies Na+ permeability on chick dorsal root ganglion cells.
Toxicon : official journal of the International Society on Toxinology 1994;32(12):1487-93.
1994: Valdivia H H; Martin B M; Ramírez A N; Fletcher P L; Possani L D
Isolation and pharmacological characterization of four novel Na+ channel-blocking toxins from the scorpion Centruroides noxius Hoffmann.
Journal of biochemistry 1994;116(6):1383-91.
1994: Fletcher M D; Possani L D; Fletcher P L
Morphological studies by light and electron microscopy of pancreatic acinar cells under the effect of Tityus serrulatus venom.
Cell and tissue research 1994;278(2):255-64.
1994: Martin B M; Ramirez A N; Gurrola G B; Nobile M; Prestipino G; Possani L D
Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch.
The Biochemical journal 1994;304 ( Pt 1)():51-6.
1994: Dehesa-Dávila M; Possani L D
Scorpionism and serotherapy in Mexico.
Toxicon : official journal of the International Society on Toxinology 1994;32(9):1015-8.
1994: Lebreton F; Delepierre M; Ramírez A N; Balderas C; Possani L D
Primary and NMR three-dimensional structure determination of a novel crustacean toxin from the venom of the scorpion Centruroides limpidus limpidus Karsch.
Biochemistry 1994;33(37):11135-49.
1994: Gurrola G B; Moreno-Hagelsieb G; Zamudio F Z; García M; Soberon X; Possani L D
The disulfide bridges of toxin 2 from the scorpion Centruroides noxius Hoffmann and its three-dimensional structure calculated using the coordinates of variant 3 from Centruroides sculpturatus.
FEBS letters 1994;347(1):59-62.
1994: Nobile M; Magnelli V; Lagostena L; Mochca-Morales J; Possani L D; Prestipino G
The toxin helothermine affects potassium currents in newborn rat cerebellar granule cells.
The Journal of membrane biology 1994;139(1):49-55.
1994: Ramírez A N; Martin B M; Gurrola G B; Possani L D
Isolation and characterization of a novel toxin from the venom of the scorpion Centruroides limpidus limpidus Karsch.
Toxicon : official journal of the International Society on Toxinology 1994;32(4):479-90.
1993: Becerril B; Corona M; Mejía M C; Martin B M; Lucas S; Bolivar F; Possani L D
The genomic region encoding toxin gamma from the scorpion Tityus serrulatus contains an intron.
FEBS letters 1993;335(1):6-8.
1993: Vaca L; Gurrola G B; Possani L D; Kunze D L
Blockade of a KCa channel with synthetic peptides from noxiustoxin: a K+ channel blocker.
The Journal of membrane biology 1993;134(2):123-9.
1993: Becerril B; Vázquez A; García C; Corona M; Bolivar F; Possani L D
Cloning and characterization of cDNAs that code for Na(+)-channel-blocking toxins of the scorpion Centruroides noxius Hoffmann.
Gene 1993;128(2):165-71.
1993: Calderon-Aranda E S; Hozbor D; Possani L D
Neutralizing capacity of murine sera induced by different antigens of scorpion venom.
Toxicon : official journal of the International Society on Toxinology 1993;31(3):327-37.
1993: Vázquez A; Becerril B; Martin B M; Zamudio F; Bolívar F; Possani L D
Primary structure determination and cloning of the cDNA encoding toxin 4 of the scorpion Centruroides noxius Hoffmann.
FEBS letters 1993;320(1):43-6.
1992: Possani L D; Martin B M; Yatani A; Mochca-Morales J; Zamudio F Z; Gurrola G B; Brown A M
Isolation and physiological characterization of taicatoxin, a complex toxin with specific effects on calcium channels.
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1343-64.
1992: Valdivia H H; Martin B M; Escobar L; Possani L D
Noxiustoxin and leiurutoxin III, two homologous peptide toxins with binding properties to synaptosomal membrane K+ channels.
Biochemistry international 1992;27(6):953-62.
1992: Fletcher P L; Fletcher M D; Possani L D
Characteristics of pancreatic exocrine secretion produced by venom from the Brazilian scorpion, Tityus serrulatus.
European journal of cell biology 1992;58(2):259-70.
1992: Possani L D; Mochca-Morales J; Amezcua J; Martin B M; Prestipino G; Nobile M
Anionic currents of chick sensory neurons are affected by a phospholipase A2 purified from the venom of the taipan snake.
Biochimica et biophysica acta 1992;1134(3):210-6.
1992: Zamudio F; Saavedra R; Martin B M; Gurrola-Briones G; Hérion P; Possani L D
Amino acid sequence and immunological characterization with monoclonal antibodies of two toxins from the venom of the scorpion Centruroides noxius Hoffmann.
European journal of biochemistry / FEBS 1992;204(1):281-92.
1991: Possani L D; Martin B M; Fletcher M D; Fletcher P L
Discharge effect on pancreatic exocrine secretion produced by toxins purified from Tityus serrulatus scorpion venom.
The Journal of biological chemistry 1991;266(5):3178-85.
1990: Colden-Stanfield M; Schilling W P; Possani L D; Kunze D L
Bradykinin-induced potassium current in cultured bovine aortic endothelial cells.
The Journal of membrane biology 1990;116(3):227-38.
1990: Ramírez G A; Fletcher P L; Possani L D
Characterization of the venom from Crotalus molossus nigrescens Gloyd (black tail rattlesnake): isolation of two proteases.
Toxicon : official journal of the International Society on Toxinology 1990;28(3):285-97.
1990: Mochca-Morales J; Martin B M; Possani L D
Isolation and characterization of helothermine, a novel toxin from Heloderma horridum horridum (Mexican beaded lizard) venom.
Toxicon : official journal of the International Society on Toxinology 1990;28(3):299-309.
1989: Prestipino G; Valdivia H H; Liévano A; Darszon A; Ramírez A N; Possani L D
Purification and reconstitution of potassium channel proteins from squid axon membranes.
FEBS letters 1989;250(2):570-4.
1989: Kirsch G E; Skattebøl A; Possani L D; Brown A M
Modification of Na channel gating by an alpha scorpion toxin from Tityus serrulatus.
The Journal of general physiology 1989;93(1):67-83.
1989: Gurrola G B; Molinar-Rode R; Sitges M; Bayon A; Possani L D
Synthetic peptides corresponding to the sequence of noxiustoxin indicate that the active site of this K+ channel blocker is located on its amino-terminal portion.
Journal of neural transmission 1989;77(1):11-20.
1988: Yatani A; Kirsch G E; Possani L D; Brown A M
Effects of New World scorpion toxins on single-channel and whole cell cardiac sodium currents.
The American journal of physiology 1988;254(3 Pt 2):H443-51.
1988: Valdivia H H; Smith J S; Martin B M; Coronado R; Possani L D
Charybdotoxin and noxiustoxin, two homologous peptide inhibitors of the K+ (Ca2+) channel.
FEBS letters 1988;226(2):280-4.
1988: Ramírez A N; Gurrola G B; Martin B M; Possani L D
Isolation of several toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1988;26(9):773-83.
1988: Martin B M; Carbone E; Yatani A; Brown A M; Ramírez A N; Gurrola G B; Possani L D
Amino acid sequence and physiological characterization of toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1988;26(9):785-94.
1988: Alagón A C; Guzmán H S; Martin B M; Ramírez A N; Carbone E; Possani L D
Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch.
Comparative biochemistry and physiology. B, Comparative biochemistry 1988;89(1):153-61.
1987: Brown A M; Yatani A; Lacerda A E; Gurrola G B; Possani L D
Neurotoxins that act selectively on voltage-dependent cardiac calcium channels.
Circulation research 1987;61(4 Pt 2):I6-9.
1982: Alagón A C; Maldonado M E; Juliá J Z; Sánchez C R; Possani L D
Venom from two sub-species of Heloderma horridum (Mexican beaded lizard): general characterization and purification of N-benzoyl-L-arginine ethyl ester hydrolase.
Toxicon : official journal of the International Society on Toxinology 1982;20(2):463-75.
1980: Alagón A C; Molinar R R; Possani L D; Fletcher P L; Cronan J E; Julia J Z
Venom from the snake Bothrops asper Garman. Purification and characterization of three phospholipases A2.
The Biochemical journal 1980;185(3):695-704.
1980: Dent M A; Possani L D; Ramírez G A; Fletcher P L
Purification and characterization of two mammalian toxins from the venom of the Mexican scorpion Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1980;18(3):343-50.
1980: Possani L D; Fletcher P L; Alagón A B; Alagón A C; Juliá J Z
Purification and characterization of a mammalian toxin from venom of the Mexican scorpion, Centruroides limpidus tecomanus Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1980;18(2):175-83.

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