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Lourival Possani

Research Profile

Chemicals & Drugs

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Amino Acid Sequences

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Lorenzo Sánchez-Vásquez; Jesus Silva-Sanchez; Maria C Rodríguez; Adela Rodríguez-Romero; Georgina B Gurrola; Juana Maria Jiménez-Vargas; Carlos Muñoz-Garay; Lourival D Possani
Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin.
Figen Caliskan; Fredy I Coronas-Valderrama; Gerardo Corzo; Veronica Quintero-Hernández; Rita Restano-Cassulini; Lourival D Possani
Molecular cloning and biochemical characterization of the first Na(+)-channel α-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom.
Caroline B F Mourão; Lourival D Possani; Rita Restano-Cassulini; Eder A Barbosa; Carlos Bloch; Mari D Heghinian; Frank Marí; Elisabeth Schwartz
Characterization of a novel peptide toxin from Acanthoscurria paulensis spider venom: a distinct cysteine assignment to the HWTX-II family.

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All Publications

2013: Lorenzo Sánchez-Vásquez; Jesus Silva-Sanchez; Maria C Rodríguez; Adela Rodríguez-Romero; Georgina B Gurrola; Juana Maria Jiménez-Vargas; Carlos Muñoz-Garay; Lourival D Possani
Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin.
Biochimica et biophysica acta 2013;1830(6):3427-36.
2013: Figen Caliskan; Fredy I Coronas-Valderrama; Gerardo Corzo; Veronica Quintero-Hernández; Rita Restano-Cassulini; Lourival D Possani
Molecular cloning and biochemical characterization of the first Na(+)-channel α-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom.
Biochimie 2013;95(6):1216-22.
2013: Caroline B F Mourão; Lourival D Possani; Rita Restano-Cassulini; Eder A Barbosa; Carlos Bloch; Mari D Heghinian; Frank Marí; Elisabeth Schwartz
Characterization of a novel peptide toxin from Acanthoscurria paulensis spider venom: a distinct cysteine assignment to the HWTX-II family.
Biochemistry 2013;52(14):2440-52.
2013: Manuel B. Aguilar; Baltazar Becerril; Quentin Kaas; Estuardo López-Vera; Ernesto Ortiz; Lourival D Possani; Edgar P Heimer de la Cotera
Precursor De13.1 from Conus delessertii defines the novel G gene superfamily.
Peptides 2013;41():17-20.
2013: Karen Luna-Ramírez; Veronica Quintero-Hernández; Leonel Vargas-Jaimes; Kenneth D Winkel; Cesar V F Batista; Lourival D Possani
Characterization of the venom from the Australian scorpion Urodacus yaschenkoi: Molecular mass analysis of components, cDNA sequences and peptides with antimicrobial activity.
Toxicon : official journal of the International Society on Toxinology 2013;63():44-54.
2013: Johanna Bernáldez; Gerardo Corzo; David E García; Samanta Jiménez; Oscar Martínez; Lourival D Possani; Sergio A Román-González; Oscar Vivas; Isabel Arenas; Roberto Arreguín; Alexei Licea
A Conus regularis Conotoxin with a Novel Eight-Cysteine Framework Inhibits CaV2.2 Channels and Displays an Anti-Nociceptive Activity.
Marine drugs 2013;11(4):1188-202.
2013: Martha Pedraza Escalona; Lourival D Possani
Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects.
Frontiers in bioscience : a journal and virtual library 2013;18():572-87.
2013: Francia Garcia; Jorge F Paniagua-Solis; Lourival D Possani; Alexis Rodriguez; Gabriel Sandoval-Lopez; Villegas Villarreal Elba Crsitina; Gerardo Pavel Espino-Solis; Gerardo Corzo
Antimicrobial peptides from arachnid venoms and their microbicidal activity in the presence of commercial antibiotics.
The Journal of antibiotics 2013;66(1):3-10.
2012: Xueli Wang; Chenqi Xu; Juana Maria Jimenez-Vargas; Lourival D Possani; Shunyi Zhu
Positive selection-guided mutational analysis revealing two key functional sites of scorpion ERG K(+) channel toxins.
Biochemical and biophysical research communications 2012;429(1-2):111-6.
2012: Herlinda Clement; George V Odell; Alejandro Olvera; Laura A Palomares; Lourival D Possani; Mabel Rodríguez; Alejandro Alagón; Fernando Z Zamudio; Rosana Sánchez-López
Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.
Toxicon : official journal of the International Society on Toxinology 2012;60(7):1223-7.
2012: Herlinda Clement; Vanessa Costa de Oliveira; Alejandro Alagón; Melisa Bérnard Valle; Silvia E Hajos; Néstor R Lago; Lourival D Possani; NORMA VALDEZ Cruz; Fernando Z Zamudio; Adolfo de Roodt
Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A₂ from Bothrops (Rhinocerophis) ammodytoides venom.
Toxicon : official journal of the International Society on Toxinology 2012;60(7):1314-23.
2012: Everardo Remi Rodríguez-Rodríguez; Baltazar Becerril; Luis Gabriel Contreras-Ferrat; Luis M Ledezma-Candanoza; Timoteo Olamendi-Portugal; Lourival D Possani; Lidia Riaño-Umbarila
A single mutation in framework 2 of the heavy variable domain improves the properties of a diabody and a related single-chain antibody.
Journal of molecular biology 2012;423(3):337-50.
2012: J M Jiménez-Vargas; R Restano-Cassulini; Lourival D Possani
Toxin modulators and blockers of hERG K(+) channels.
Toxicon : official journal of the International Society on Toxinology 2012;60(4):492-501.
2012: Figen Caliskan; Fredy I V Coronas; Gerardo Corzo; Blanca Inés García; Ferhan Korkmaz; Rita Restano-Cassulini; Yalcin Sahin; Lourival D Possani
Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda.
Peptides 2012;37(1):106-12.
2012: Zoltan Varga; Christine Beeton; Luis Cardenas; Rezso Gaspar; Georgina Gurrola-Briones; Ferenc Papp; Gustavo Pedraza-Alva; Lourival D Possani; Ricardo C Rodríguez de la Vega; Yvonne Rosenstein; Rajeev B Tajhya; György Panyi
Vm24, a natural immunosuppressive peptide, potently and selectively blocks Kv1.3 potassium channels of human T cells.
Molecular pharmacology 2012;82(3):372-82.
2012: Georgina B Gurrola; Rogelio A Hernández-López; György Panyi; Cesar V F Batista; Federico del Río-Portilla; Ricardo C Rodríguez de la Vega; Saida P Salas-Castillo; Zoltan Varga; Lourival D Possani
Structure, function, and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes.
Biochemistry 2012;51(19):4049-61.
2012: J M Jimenez-Vargas; R Restano-Cassulini; Lourival D Possani
Interacting sites of scorpion toxin ErgTx1 with hERG1 K+ channels.
Toxicon : official journal of the International Society on Toxinology 2012;59(6):633-41.
2012: Veronica Quintero-Hernández; Israel Alcántara-Recillas; Luis Del Pozo-Yauner; Victor Rivelino Juárez-González; Martha Pedraza-Escalona; Lourival D Possani; Baltazar Becerril
Evaluation of three different formats of a neutralizing single chain human antibody against toxin Cn2: neutralization capacity versus thermodynamic stability.
Immunology letters 2012;143(2):152-60.
2012: Santos Ramírez-Carreto; Lourival D Possani; Veronica Quintero-Hernández; Baltazar Becerril; Gerardo Corzo; Juana María Jiménez-Vargas; Ernesto Ortiz
Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae.
Peptides 2012;34(2):290-5.
2012: Alma L Saucedo; Federico del Rio-Portilla; Muriel DELEPIERRE; Georgina Estrada; Cristiana Picco; Lourival D Possani; Gianfranco Prestipino; Gerardo Corzo
Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion Centruroides suffusus suffusus, and their effects on Nav1.5 sodium channels.
Biochimica et biophysica acta 2012;1824(3):478-87.
2012: Figen Caliskan; Fredy I V Coronas; V Quintero-Hernández; Rita Restano-Cassulini; Fernando Z Zamudio; Cesar V F Batista; Lourival D Possani
Turkish scorpion Buthacus macrocentrus: general characterization of the venom and description of Bu1, a potent mammalian Na⁺-channel α-toxin.
Toxicon : official journal of the International Society on Toxinology 2012;59(3):408-15.
2012: Emanuele Schiavon; Enzo Wanke; Gerardo Corzo; Georgina B Gurrola; Timoteo Olamendi-Portugal; Martha Pedraza-Escalona; Lourival D Possani
Negative-shift activation, current reduction and resurgent currents induced by β-toxins from Centruroides scorpions in sodium channels.
Toxicon : official journal of the International Society on Toxinology 2012;59(2):283-93.
2012: Martha Rendón-Anaya; Lourival D Possani; Luis Delaye; Alfredo Herrera-Estrella
Global transcriptome analysis of the scorpion Centruroides noxius: new toxin families and evolutionary insights from an ancestral scorpion species.
PloS one 2012;7(8):e43331.
2012: Jimmy A Guerrero-Vargas; Caroline B F Mourão; Lourival D Possani; Veronica Quintero-Hernández; Elisabeth Schwartz
Identification and phylogenetic analysis of Tityus pachyurus and Tityus obscurus novel putative Na+-channel scorpion toxins.
PloS one 2012;7(2):e30478.
2011: Veronica Quintero-Hernández; M Rendón-Anaya; E F Schwartz; Baltazar Becerril; G Corzo; E Ortiz; Lourival D Possani
Scorpion and spider venom peptides: gene cloning and peptide expression.
Toxicon : official journal of the International Society on Toxinology 2011;58(8):644-63.
2011: Itzel Amaro; Baltazar Becerril; Lidia Riaño-Umbarila; Lourival D Possani
Isolation and characterization of a human antibody fragment specific for Ts1 toxin from Tityus serrulatus scorpion.
Immunology letters 2011;139(1-2):73-9.
2011: B I García-Gómez; R Restano-Cassulini; R R Rodríguez; F I V Coronas; Lourival D Possani
Biochemical and molecular characterization of the venom from the Cuban scorpion Rhopalurus junceus.
Toxicon : official journal of the International Society on Toxinology 2011;58(1):18-27.
2011: Juan Carlos Canul-Tec; Lidia Riaño-Umbarila; Enrique Rudiño-Piñera; Baltazar Becerril; Lourival D Possani; Alfredo Torres-Larios
Structural basis of neutralization of the major toxic component from the scorpion Centruroides noxius Hoffmann by a human-derived single-chain antibody fragment.
The Journal of biological chemistry 2011;286(23):20892-900.
2011: Gerardo Pavel Espino-Solis; Georgina Estrada; Timoteo Olamendi-Portugal; Villegas Villarreal Elba Crsitina; Fernando Z Zamudio; Sandrine Cestele; Lourival D Possani; Gerardo Corzo
Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus.
Toxicon : official journal of the International Society on Toxinology 2011;57(5):739-46.
2011: J M Jimenez-Vargas; R Restano-Cassulini; V Quintero-Hernández; G B Gurrola; Lourival D Possani
Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function.
Peptides 2011;32(3):560-7.
2011: Lidia Riaño-Umbarila; Gabriel Contreras-Ferrat; Timoteo Olamendi-Portugal; Citlalli Morelos-Juárez; Gerardo Corzo; Lourival D Possani; Baltazar Becerril
Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment.
The Journal of biological chemistry 2011;286(8):6143-51.
2011: Georgina Estrada; Rita Restano-Cassulini; Ernesto Ortiz; Lourival D Possani; Gerardo Corzo
Addition of positive charges at the C-terminal peptide region of CssII, a mammalian scorpion peptide toxin, improves its affinity for sodium channels Nav1.6.
Peptides 2011;32(1):75-9.
2011: Cynthia A Hernández-Aponte; Jesus Silva-Sanchez; Veronica Quintero-Hernández; Adela Rodríguez-Romero; Cipriano Balderas; Lourival D Possani; Georgina B Gurrola
Vejovine, a new antibiotic from the scorpion venom of Vaejovis mexicanus.
Toxicon : official journal of the International Society on Toxinology 2011;57(1):84-92.
2011: L L Corrales-Garcia; Lourival D Possani; Gerardo Corzo
Expression systems of human β-defensins: vectors, purification and biological activities.
Amino acids 2011;40(1):5-13.
2011: A Rodríguez; Villegas Villarreal Elba Crsitina; H Satake; Lourival D Possani; Gerardo Corzo
Amino acid substitutions in an alpha-helical antimicrobial arachnid peptide affect its chemical properties and biological activity towards pathogenic bacteria but improves its therapeutic index.
Amino acids 2011;40(1):61-8.
2010: Ricardo C Rodríguez de la Vega; Elisabeth F Schwartz; Lourival D Possani
Mining on scorpion venom biodiversity.
Toxicon : official journal of the International Society on Toxinology 2010;56(7):1155-61.
2010: Thomas Vandendriessche; Timoteo Olamendi-Portugal; Fernando Z Zamudio; Lourival D Possani; Jan Tytgat
Isolation and characterization of two novel scorpion toxins: The alpha-toxin-like CeII8, specific for Na(v)1.7 channels and the classical anti-mammalian CeII9, specific for Na(v)1.4 channels.
Toxicon : official journal of the International Society on Toxinology 2010;56(4):613-23.
2010: Shunyi Zhu; Bin Gao; André Aumelas; Maria del Carmen Rodríguez; Humberto Lanz-Mendoza; Steve Peigneur; Elia Diego-Garcia; Marie-France Martin-Eauclaire; Jan Tytgat; Lourival D Possani
MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity.
Biochimica et biophysica acta 2010;1804(4):872-83.
2010: Elisa Redaelli; Rita Restano Cassulini; Deyanira Fuentes Silva; Herlinda Clement; Emanuele Schiavon; Fernando Z Zamudio; George Odell; Annarosa Arcangeli; Jeffrey J Clare; Alejandro Alagón; Ricardo C Rodríguez de la Vega; Lourival D Possani; Enzo Wanke
Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
The Journal of biological chemistry 2010;285(6):4130-42.
2010: Adolfo de Roodt; Fredy I V Coronas; Nestor Lago; María E González; Rodrigo D Laskowicz; Juan C Beltramino; Silvina Saavedra; Raúl A López; Gustavo J Reati; Miriam G Vucharchuk; Eduardo Bazán; Liliana Varni; Oscar D Salomón; Lourival D Possani
General biochemical and immunological characterization of the venom from the scorpion Tityus trivittatus of Argentina.
Toxicon : official journal of the International Society on Toxinology 2010;55(2-3):307-19.
2009: Gerardo P Espino-Solis; J Calderon-Amador; E S Calderon-Aranda; A F Licea; L Donis-Maturano; L Flores-Romo; Lourival D Possani
Rational design of synthetic peptides to generate antibodies that recognize in situ CD11c(+) putative dendritic cells in horse lymph nodes.
Veterinary immunology and immunopathology 2009;132(2-4):181-90.
2009: Gerardo Corzo; Ada Prochnicka-Chalufour; Blanca I García; Lourival D Possani; Muriel DELEPIERRE
Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus.
Biochimica et biophysica acta 2009;1794(11):1591-8.
2009: Ferenc Papp; Cesar V F Batista; Zoltan Varga; Monika Herceg; Sergio A Román-González; Rezso Gaspar; Lourival D Possani; György Panyi
Tst26, a novel peptide blocker of Kv1.2 and Kv1.3 channels from the venom of Tityus stigmurus.
Toxicon : official journal of the International Society on Toxinology 2009;54(4):379-89.
2009: Edelyn C N Silva; Thalita S Camargos; Andrea Q Maranhão; Ildinete Silva-Pereira; Luciano P Silva; Lourival D Possani; Elisabeth Schwartz
Cloning and characterization of cDNA sequences encoding for new venom peptides of the Brazilian scorpion Opisthacanthus cayaporum.
Toxicon : official journal of the International Society on Toxinology 2009;54(3):252-61.
2009: Kenya Hernández-Salgado; Georgina Estrada; Alejandro Olvera; Fredy I Coronas; Lourival D Possani; Gerardo Corzo
Heterologous expressed toxic and non-toxic peptide variants of toxin CssII are capable to produce neutralizing antibodies against the venom of the scorpion Centruroides suffusus suffusus.
Immunology letters 2009;125(2):93-9.
2009: Gina D'Suze; Elisabeth F Schwartz; B I García-Gómez; Carlos Sevcik; Lourival D Possani
Molecular cloning and nucleotide sequence analysis of genes from a cDNA library of the scorpion Tityus discrepans.
Biochimie 2009;91(8):1010-9.
2009: Gerardo Corzo; Cedric Bernard; Herlinda Clement; Villegas Villarreal Elba Crsitina; Frank Bosmans; Jan Tytgat; Lourival D Possani; Herve Darbon; Alejandro Alagón
Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2.
Biochimica et biophysica acta 2009;1794(8):1190-6.
2009: Lidia González-Morales; Elia Diego-García; Lorenzo Segovia; Maria del Carmen Gutiérrez; Lourival D Possani
Venom from the centipede Scolopendra viridis Say: purification, gene cloning and phylogenetic analysis of a phospholipase A2.
Toxicon : official journal of the International Society on Toxinology 2009;54(1):8-15.
2009: Elisabeth Schwartz; E Michelle Capes; Elia Diego-García; Fernando Z Zamudio; Oscar Fuentes; Lourival D Possani; Héctor H Valdivia
Characterization of hadrucalcin, a peptide from Hadrurus gertschi scorpion venom with pharmacological activity on ryanodine receptors.
British journal of pharmacology 2009;157(3):392-403.
2009: Blanca I García-Gómez; Timoteo C Olamendi-Portugal; Jorge Paniagua; Jurg van der Walt; Karin Dyason; Lourival D Possani
Heterologous expression of a gene that codes for Pg8, a scorpion toxin of Parabuthus granulatus, capable of generating protecting antibodies in mice.
Toxicon : official journal of the International Society on Toxinology 2009;53(7-8):770-8.
2009: Gianfranco Prestipino; Gerardo Corzo; Stefania Romeo; Anna Rosa Murgia; Ilaria Zanardi; Georgina B Gurrola; Lourival D Possani
Scorpion toxins that block transient currents (I(A)) of rat cerebellum granular cells.
Toxicology letters 2009;187(1):1-9.
2009: G P Espino-Solis; L Riaño-Umbarila; Baltazar Becerril; Lourival D Possani
Antidotes against venomous animals: state of the art and prospectives.
Journal of proteomics 2009;72(2):183-99.
2008: Vera L Petricevich; Enrique Reynaud; A H Cruz; Lourival D Possani
Macrophage activation, phagocytosis and intracellular calcium oscillations induced by scorpion toxins from Tityus serrulatus.
Clinical and experimental immunology 2008;154(3):415-23.
2008: Gerardo Corzo; Elia Diego-García; Herlinda Clement; Steve Peigneur; George Odell; Jan Tytgat; Lourival D Possani; Alejandro Alagón
An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.
Peptides 2008;29(11):1901-8.
2008: Gerardo Corzo; Ferenc Papp; Zoltan Varga; Omar Barraza; Pavel G Espino-Solis; Ricardo C Rodríguez de la Vega; Rezso Gaspar; Gyorgy Panyi; Lourival D Possani
A selective blocker of Kv1.2 and Kv1.3 potassium channels from the venom of the scorpion Centruroides suffusus suffusus.
Biochemical pharmacology 2008;76(9):1142-54.
2008: Yousra Abdel-Mottaleb; Gerardo Corzo; Marie-France Martin-Eauclaire; Honoo Satake; Brigitte Céard; Steve Peigneur; Praveen Nambaru; Pierre E BOUGIS; Lourival D Possani; Jan Tytgat
A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K+ channels.
Biochemical pharmacology 2008;76(6):805-15.
2008: Rita Restano-Cassulini; Timoteo Olamendi-Portugal; Fernando Z Zamudio; Baltazar Becerril; Lourival D Possani
Two novel ergtoxins, blockers of K+-channels, purified from the Mexican scorpion Centruroides elegans elegans.
Neurochemical research 2008;33(8):1525-33.
2008: Elisabeth Schwartz; Thalita S Camargos; Fernando Z Zamudio; Luciano P Silva; Carlos Bloch; Fabio Caixeta; Carlos Alberto Schwartz; Lourival D Possani
Mass spectrometry analysis, amino acid sequence and biological activity of venom components from the Brazilian scorpion Opisthacanthus cayaporum.
Toxicon : official journal of the International Society on Toxinology 2008;51(8):1499-508.
2008: Timoteo Olamendi-Portugal; Cesar V F Batista; Rita Restano-Cassulini; Victoria Pando; Oscar Villa-Hernandez; Alfonso Zavaleta-Martínez-Vargas; Maria C Salas-Arruz; Ricardo C Rodríguez de la Vega; Baltazar Becerril; Lourival D Possani
Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.
Proteomics 2008;8(9):1919-32.
2008: Gerardo P Espino-Solis; Joel Osuna-Quintero; Lourival D Possani
Molecular cloning and characterization of the alphaX subunit from CD11c/CD18 horse integrin.
Veterinary immunology and immunopathology 2008;122(3-4):326-34.
2008: Stefania Romeo; Gerardo Corzo; Attilio Vasile; Honoo Satake; Gianfranco Prestipino; Lourival D Possani
A positive charge at the N-terminal segment of Discrepin increases the blocking effect of K+ channels responsible for the IA currents in cerebellum granular cells.
Biochimica et biophysica acta 2008;1780(4):750-5.
2008: Elia Diego-García; Yousra Abdel-Mottaleb; Elisabeth Schwartz; R C Rodríguez de la Vega; Jan Tytgat; Lourival D Possani
Cytolytic and K+ channel blocking activities of beta-KTx and scorpine-like peptides purified from scorpion venoms.
Cellular and molecular life sciences : CMLS 2008;65(1):187-200.
2007: Vera L Petricevich; Anselmo Hernández Cruz; Fredy I V Coronas; Lourival D Possani
Toxin gamma from Tityus serrulatus scorpion venom plays an essential role in immunomodulation of macrophages.
Toxicon : official journal of the International Society on Toxinology 2007;50(5):666-75.
2007: Estuardo López-Vera; Manuel B. Aguilar; Emanuele Schiavon; Chiara Marinzi; Ernesto Ortiz; Rita Restano-Cassulini; Cesar V F Batista; Lourival D Possani; Edgar P Heimer-de la Cotera; Francesco Peri; Baltazar Becerril; Enzo Wanke
Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.
The FEBS journal 2007;274(15):3972-85.
2007: Georgina Estrada; Blanca I Garcia; Emanuele Schiavon; Ernesto Ortiz; Sandrine Cestele; Enzo Wanke; Lourival D Possani; Gerardo Corzo
Four disulfide-bridged scorpion beta neurotoxin CssII: heterologous expression and proper folding in vitro.
Biochimica et biophysica acta 2007;1770(8):1161-8.
2007: NORMA VALDEZ Cruz; Lorenzo Segovia; Miguel Corona; Lourival D Possani
Sequence analysis and phylogenetic relationship of genes encoding heterodimeric phospholipases A2 from the venom of the scorpion Anuroctonus phaiodactylus.
Gene 2007;396(1):149-58.
2007: Herlinda Clement; George Odell; Fernando Z Zamudio; Elisa Redaelli; Enzo Wanke; Alejandro Alagón; Lourival D Possani
Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels.
Toxicon : official journal of the International Society on Toxinology 2007;50(1):65-74.
2007: Cesar V F Batista; S A Román-González; S P Salas-Castillo; Fernando Z Zamudio; Froylan Gómez-Lagunas; Lourival D Possani
Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2007;146(1-2):147-57.
2007: Ricardo C Rodríguez de la Vega; Lourival D Possani
Novel paradigms on scorpion toxins that affects the activating mechanism of sodium channels.
Toxicon : official journal of the International Society on Toxinology 2007;49(2):171-80.
2007: Veronica Quintero-Hernández; Victor Rivelino Juárez-González; Mauricio Ortíz-León; Rosalba Sánchez; Lourival D Possani; Baltazar Becerril
The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies.
Molecular immunology 2007;44(6):1307-15.
2007: Elisabeth Schwartz; Elia Diego-Garcia; Ricardo C Rodríguez de la Vega; Lourival D Possani
Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones).
BMC genomics 2007;8():119.
2007: Elia Diego-García; Elisabeth Schwartz; Gina D'Suze; Sergio A Román González; Cesar V F Batista; Blanca Inés García; Ricardo C Rodríguez de la Vega; Lourival D Possani
Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components.
Peptides 2007;28(1):31-7.
2006: Elisabeth Schwartz; Carlos Alberto Schwartz; Froylan Gómez-Lagunas; Fernando Z Zamudio; Lourival D Possani
HgeTx1, the first K+-channel specific toxin characterized from the venom of the scorpion Hadrurus gertschi Soleglad.
Toxicon : official journal of the International Society on Toxinology 2006;48(8):1046-53.
2006: Emanuele Schiavon; Tiziana Sacco; Rita Restano Cassulini; Georgina B Gurrola; Filippo Tempia; Lourival D Possani; Enzo Wanke
Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons.
The Journal of biological chemistry 2006;281(29):20326-37.
2006: Figen Caliskan; Blanca Inés García; Fredy I V Coronas; Cesar V F Batista; Fernando Z Zamudio; Lourival D Possani
Characterization of venom components from the scorpion Androctonus crassicauda of Turkey: peptides and genes.
Toxicon : official journal of the International Society on Toxinology 2006;48(1):12-22.
2006: Cesar V F Batista; Gina D'Suze; Froylan Gómez-Lagunas; Fernando Z Zamudio; Sergio Encarnación; Carlos Sevcik; Lourival D Possani
Proteomic analysis of Tityus discrepans scorpion venom and amino acid sequence of novel toxins.
Proteomics 2006;6(12):3718-27.
2006: Dietrich Mebs; Ulrich Kuch; Fredy I V Coronas; Cesar V F Batista; Andreas Gumprecht; Lourival D Possani
Biochemical and biological activities of the venom of the Chinese pitviper Zhaoermia mangshanensis, with the complete amino acid sequence and phylogenetic analysis of a novel Arg49 phospholipase A2 myotoxin.
Toxicon : official journal of the International Society on Toxinology 2006;47(7):797-811.
2006: Rita Restano-Cassulini; Yuliya V Korolkova; Sylvie Diochot; Georgina B Gurrola; Leonardo Guasti; Lourival D Possani; Michel Lazdunski; Eugene V Grishin; Annarosa Arcangeli; Enzo Wanke
Species diversity and peptide toxins blocking selectivity of ether-a-go-go-related gene subfamily K+ channels in the central nervous system.
Molecular pharmacology 2006;69(5):1673-83.
2006: Ada Prochnicka-Chalufour; Gerardo Corzo; Honoo Satake; Marie-France Martin-Eauclaire; Anna Rosa Murgia; Gianfranco Prestipino; Gina D'Suze; Lourival D Possani; Muriel DELEPIERRE
Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily.
Biochemistry 2006;45(6):1795-804.
2006: Yousra Abdel-Mottaleb; Fredy V Coronas; Adolfo de Roodt; Lourival D Possani; Jan Tytgat
A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily.
FEBS letters 2006;580(2):592-6.
2006: György Panyi; Lourival D Possani; Ricardo C Rodríguez de la Vega; Rezso Gáspár; Zoltán Varga
K+ channel blockers: novel tools to inhibit T cell activation leading to specific immunosuppression.
Current pharmaceutical design 2006;12(18):2199-220.
2006: Jacqueline Barona; Cesar V F Batista; Fernando Z Zamudio; Froylan Gomez-Lagunas; Enzo Wanke; Rafael Otero; Lourival D Possani
Proteomic analysis of the venom and characterization of toxins specific for Na+ - and K+ -channels from the Colombian scorpion Tityus pachyurus.
Biochimica et biophysica acta 2006;1764(1):76-84.
2005: Ricardo C Rodríguez de la Vega; Lourival D Possani
Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution.
Toxicon : official journal of the International Society on Toxinology 2005;46(8):831-44.
2005: Timoteo Olamendi-Portugal; Sándor Somodi; Juan Antonio Fernández; Fernando Z Zamudio; Baltazar Becerril; Zoltán Varga; György Panyi; Rezso Gáspár; Lourival D Possani
Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockade Kv1.3 over IKCa1 K+ channels of T cells.
Toxicon : official journal of the International Society on Toxinology 2005;46(4):418-29.
2005: Manuel B. Aguilar; Estuardo López-Vera; Ernesto Ortiz; Baltazar Becerril; Lourival D Possani; Baldomero M Olivera; Edgar P Heimer-de la Cotera
A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues.
Biochemistry 2005;44(33):11130-6.
2005: Alejandro Padilla; Tzipe Govezensky; Lourival D Possani; Carlos Larralde
Mortality and antibody responses of mice to three successive episodes of experimental scorpion (Centruroides limpidus limpidus) envenomation and immunological rescue.
Toxicon : official journal of the International Society on Toxinology 2005;46(2):142-9.
2005: Ricardo C Rodríguez de la Vega; Lourival D Possani
On the evolution of invertebrate defensins.
Trends in genetics : TIG 2005;21(6):330-2.
2005: Karlen G Gazarian; Tatiana G Gazarian; Ricardo Hernández; Lourival D Possani
Immunology of scorpion toxins and perspectives for generation of anti-venom vaccines.
Vaccine 2005;23(26):3357-68.
2005: Lidia Riaño-Umbarila; Victor Rivelino Juárez-González; Timoteo Olamendi-Portugal; Mauricio Ortíz-León; Lourival D Possani; Baltazar Becerril
A strategy for the generation of specific human antibodies by directed evolution and phage display. An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom.
The FEBS journal 2005;272(10):2591-601.
2005: Miklós Bagdány; Cesar V F Batista; NORMA VALDEZ Cruz; Sándor Somodi; Ricardo C Rodriguez de la Vega; Alexei F Licea; Zoltán Varga; Rezso Gáspár; Lourival D Possani; György Panyi
Anuroctoxin, a new scorpion toxin of the alpha-KTx 6 subfamily, is highly selective for Kv1.3 over IKCa1 ion channels of human T lymphocytes.
Molecular pharmacology 2005;67(4):1034-44.
2005: Victor Rivelino Juárez-González; L Riaño-Umbarila; Veronica Quintero-Hernández; Timoteo Olamendi-Portugal; M Ortiz-León; E Ortíz; Lourival D Possani; Baltazar Becerril
Directed evolution, phage display and combination of evolved mutants: a strategy to recover the neutralization properties of the scFv version of BCF2 a neutralizing monoclonal antibody specific to scorpion toxin Cn2.
Journal of molecular biology 2005;346(5):1287-97.
2005: Elia Diego-García; Cesar V F Batista; Blanca I García-Gómez; Sylvia Lucas; Denise M Candido; Froylan Gómez-Lagunas; Lourival D Possani
The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function.
Toxicon : official journal of the International Society on Toxinology 2005;45(3):273-83.
2004: NORMA VALDEZ Cruz; Cesar V F Batista; Fernando Z Zamudio; Frank Bosmans; Jan Tytgat; Lourival D Possani
Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus.
European journal of biochemistry / FEBS 2004;271(23-24):4753-61.
2004: Gina D'Suze; Cesar V F Batista; Andrea Frau; Anna Rosa Murgia; Fernando Z Zamudio; Carlos Sevcik; Lourival D Possani; Gianfranco Prestipino
Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+ -channels (IA currents) of cerebellum granular cells.
Archives of biochemistry and biophysics 2004;430(2):256-63.
2004: Karine Frénal; Chen-Qi Xu; Nicolas Wolff; Karine Wecker; Georgina B Gurrola; Shun-Yi Zhu; Cheng-Wu Chi; Lourival D Possani; Jan Tytgat; Muriel DELEPIERRE
Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels.
Proteins 2004;56(2):367-75.
2004: Xinsheng Zhu; Fernando Z Zamudio; Beth A Olbinski; Lourival D Possani; Héctor H Valdivia
Activation of skeletal ryanodine receptors by two novel scorpion toxins from Buthotus judaicus.
The Journal of biological chemistry 2004;279(25):26588-96.
2004: Ricardo C Rodríguez de la Vega; Lourival D Possani
Current views on scorpion toxins specific for K+-channels.
Toxicon : official journal of the International Society on Toxinology 2004;43(8):865-75.
2004: NORMA VALDEZ Cruz; Sonia Dávila; Alexei F Licea; Miguel Corona; Fernando Z Zamudio; Jesús García-Valdes; Leslie Boyer; Lourival D Possani
Biochemical, genetic and physiological characterization of venom components from two species of scorpions: Centruroides exilicauda Wood and Centruroides sculpturatus Ewing.
Biochimie 2004;86(6):387-96.
2004: Ricardo C Rodríguez de la Vega; Blanca Inés García; Chiara D'Ambrosio; Elia Diego-García; A Scaloni; Lourival D Possani
Antimicrobial peptide induction in the haemolymph of the Mexican scorpion Centruroides limpidus limpidus in response to septic injury.
Cellular and molecular life sciences : CMLS 2004;61(12):1507-19.
2004: Federico del Río-Portilla; Elizabeth Hernández-Marín; Genaro Pimienta; Fredy V Coronas; Fernando Z Zamudio; Ricardo C Rodríguez de la Vega; Enzo Wanke; Lourival D Possani
NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity.
European journal of biochemistry / FEBS 2004;271(12):2504-16.
2004: Anna Rosa Murgia; Cesar V F Batista; Gianfranco Prestipino; Lourival D Possani
Amino acid sequence and function of a new alpha-toxin from the Amazonian scorpion Tityus cambridgei.
Toxicon : official journal of the International Society on Toxinology 2004;43(6):737-40.
2004: Cesar V F Batista; Luis del Pozo; Fernando Z Zamudio; Sandra Contreras; Baltazar Becerril; Enzo Wanke; Lourival D Possani
Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;803(1):55-66.
2004: NORMA VALDEZ Cruz; Cesar V F Batista; Lourival D Possani
Phaiodactylipin, a glycosylated heterodimeric phospholipase A from the venom of the scorpion Anuroctonus phaiodactylus.
European journal of biochemistry / FEBS 2004;271(8):1453-64.
2004: Gina D'Suze; Carlos Sevcik; Miguel Corona; Fernando Z Zamudio; Cesar V F Batista; Fredy I V Coronas; Lourival D Possani
Ardiscretin a novel arthropod-selective toxin from Tityus discrepans scorpion venom.
Toxicon : official journal of the International Society on Toxinology 2004;43(3):263-72.
2004: Froylan Gómez-Lagunas; Cesar V F Batista; Timoteo Olamendi-Portugal; Martha E Ramírez-Domínguez; Lourival D Possani
Inhibition of the collapse of the Shaker K+ conductance by specific scorpion toxins.
The Journal of general physiology 2004;123(3):265-79.
2004: Isabelle Huys; Timoteo Olamendi-Portugal; Blanca Ines Garcia-Gómez; Isabel Vandenberghe; Jozef Van Beeumen; Karin Dyason; Elke Clynen; Shunyi Zhu; Jurg van der Walt; Lourival D Possani; Jan Tytgat
A subfamily of acidic alpha-K(+) toxins.
The Journal of biological chemistry 2004;279(4):2781-9.
2004: Andree Shalabi; Fernando Zamudio; Xiaoyan Wu; Andrea Scaloni; Lourival D Possani; Mitchel L Villereal
Tetrapandins, a new class of scorpion toxins that specifically inhibit store-operated calcium entry in human embryonic kidney-293 cells.
The Journal of biological chemistry 2004;279(2):1040-9.
2004: Barbara Selisko; Gabriela Cosío; Consuelo García; Baltazar Becerril; Lourival D Possani; Eduardo Horjales
Bacterial expression, purification and functional characterization of a recombinant chimeric Fab derived from murine mAb BCF2 that neutralizes the venom of the scorpion Centruroides noxius hoffmann.
Toxicon : official journal of the International Society on Toxinology 2004;43(1):43-51.
2004: Isel Pascual; Shirley Gil-Parrado; Miguel Cisneros; Patricia Joseph-Bravo; Joaquín Díaz; Lourival D Possani; Jean-Louis Charli; María Chávez
Purification of a specific inhibitor of pyroglutamyl aminopeptidase II from the marine annelide Hermodice carunculata. in vivo effects in rodent brain.
The international journal of biochemistry & cell biology 2004;36(1):138-52.
2003: Miguel Corona; Fredy V Coronas; Enrique Merino; Baltazar Becerril; Rafael Gutiérrez; Santiago Rebolledo-Antunez; David E Garcia; Lourival D Possani
A novel class of peptide found in scorpion venom with neurodepressant effects in peripheral and central nervous system of the rat.
Biochimica et biophysica acta 2003;1649(1):58-67.
2003: Fredy V Coronas; Maria Stankiewicz; Cesar V F Batista; S Giraud; J M Alam; Lourival D Possani; Dietrich Mebs; Marcel Pelhate
Primary structure and electrophysiological characterization of two almost identical isoforms of toxin from Isometrus vittatus (family: Buthidae) scorpion venom.
Toxicon : official journal of the International Society on Toxinology 2003;41(8):989-97.
2003: Alejandro Padilla; Tzipe Govezensky; Lourival D Possani; Carlos Larralde
Experimental envenoming of mice with venom from the scorpion Centruroides limpidus limpidus: differences in mortality and symptoms with and without antibody therapy relating to differences in age, sex and strain of mouse.
Toxicon : official journal of the International Society on Toxinology 2003;41(8):959-65.
2003: María del Carmen Gutiérrez; Carolina Abarca; Lourival D Possani
A toxic fraction from scolopendra venom increases the basal release of neurotransmitters in the ventral ganglia of crustaceans.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2003;135(2):205-14.
2003: Ricardo C Rodríguez de la Vega; Enrique Merino; Baltazar Becerril; Lourival D Possani
Novel interactions between K+ channels and scorpion toxins.
Trends in pharmacological sciences 2003;24(5):222-7.
2003: Lourival D Possani
The past, present, and future of biotechnology in Mexico.
Nature biotechnology 2003;21(5):582-3.
2003: Tatiana G Gazarian; Barbara Selisko; Georgina B Gurrola; Ricardo Hernández; Lourival D Possani; Karlen G Gazarian
Potential of peptides selected from random phage-displayed libraries to mimic conformational epitopes: a study on scorpion toxin Cn2 and the neutralizing monoclonal antibody BCF2.
Combinatorial chemistry & high throughput screening 2003;6(2):119-32.
2003: Consuelo Garcia; Emma S Calderón-Aranda; Gerardo A V Anguiano; Baltazar Becerril; Lourival D Possani
Analysis of the immune response induced by a scorpion venom sub-fraction, a pure peptide and a recombinant peptide, against toxin Cn2 of Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 2003;41(4):417-27.
2003: Fredy V Coronas; Adolfo de Roodt; Timoteo Olamendi Portugal; Fernando Z Zamudio; Cesar V F Batista; Froylan Gómez-Lagunas; Lourival D Possani
Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus.
Toxicon : official journal of the International Society on Toxinology 2003;41(2):173-9.
2003: Ignacio López-González; Timoteo Olamendi-Portugal; José L De la Vega-Beltrán; Jurg van der Walt; Karin Dyason; Lourival D Possani; Ricardo Felix; Alberto Darszon
Scorpion toxins that block T-type Ca2+ channels in spermatogenic cells inhibit the sperm acrosome reaction.
Biochemical and biophysical research communications 2003;300(2):408-14.
2002: Cesar V F Batista; Froylan Gómez-Lagunas; Ricardo C Rodríguez de la Vega; Péter Hajdu; György Panyi; Rezso Gáspár; Lourival D Possani
Two novel toxins from the Amazonian scorpion Tityus cambridgei that block Kv1.3 and Shaker B K(+)-channels with distinctly different affinities.
Biochimica et biophysica acta 2002;1601(2):123-31.
2002: Timoteo Olamendi-Portugal; Blanca Inés García; Ignacio López-González; Jurg van der Walt; Karin Dyason; Chris Ulens; Jan Tytgat; Ricardo Felix; Alberto Darszon; Lourival D Possani
Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels.
Biochemical and biophysical research communications 2002;299(4):562-8.
2002: Miguel Corona; Georgina B Gurrola; Enrique Merino; Rita Restano Cassulini; NORMA VALDEZ Cruz; Blanca García; Martha E Ramírez-Domínguez; Fredy I V Coronas; Fernando Z Zamudio; Enzo Wanke; Lourival D Possani
A large number of novel Ergtoxin-like genes and ERG K+-channels blocking peptides from scorpions of the genus Centruroides.
FEBS letters 2002;532(1-2):121-6.
2002: Hélène Vacher; Meriem Alami; Marcel Crest; Lourival D Possani; Pierre E Bougis; Marie-France Martin-Eauclaire
Expanding the scorpion toxin alpha-KTX 15 family with AmmTX3 from Androctonus mauretanicus.
European journal of biochemistry / FEBS 2002;269(24):6037-41.
2002: Yamileth Angulo; Timoteo Olamendi-Portugal; Alberto Alape-Girón; Lourival D Possani; Bruno Lomonte
Structural characterization and phylogenetic relationships of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a Lys49 phospholipase A(2) homologue.
The international journal of biochemistry & cell biology 2002;34(10):1268-78.
2002: Lourival D Possani; Miguel Corona; Mario Zurita; Mario H Rodríguez
From noxiustoxin to scorpine and possible transgenic mosquitoes resistant to malaria.
Archives of medical research 2002;33(4):398-404.
2002: Gerardo Corzo; Villegas Villarreal Elba Crsitina; Froylan Gómez-Lagunas; Lourival D Possani; Olga S Belokoneva; Terumi Nakajima
Oxyopinins, large amphipathic peptides isolated from the venom of the wolf spider Oxyopes kitabensis with cytolytic properties and positive insecticidal cooperativity with spider neurotoxins.
The Journal of biological chemistry 2002;277(26):23627-37.
2002: Liliana Pardo-Lopez; Mei Zhang; Jie Liu; Min Jiang; Lourival D Possani; Gea-Ny Tseng
Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule.
The Journal of biological chemistry 2002;277(19):16403-11.
2002: Marzia Lecchi; Elisa Redaelli; Barbara Rosati; Georgina B Gurrola; Tullio Florio; Olivia Crociani; Giulia Curia; Rita Restano Cassulini; Alessio Masi; Annarosa Arcangeli; Massimo Olivotto; Gennaro Schettini; Lourival D Possani; Enzo Wanke
Isolation of a long-lasting eag-related gene-type K+ current in MMQ lactotrophs and its accommodating role during slow firing and prolactin release.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(9):3414-25.
2002: Cesar V F Batista; Fernando Z Zamudio; Sylvia Lucas; Jay W Fox; Andrea Frau; Gianfranco Prestipino; Lourival D Possani
Scorpion toxins from Tityus cambridgei that affect Na(+)-channels.
Toxicon : official journal of the International Society on Toxinology 2002;40(5):557-62.
2002: Martha E Ramirez-Dominguez; Timoteo Olamendi-Portugal; Ubaldo Garcia; Consuelo Garcia; Hugo Arechiga; Lourival D Possani
Cn11, the first example of a scorpion toxin that is a true blocker of Na(+) currents in crayfish neurons.
The Journal of experimental biology 2002;205(Pt 6):869-76.
2002: Liliana Pardo-López; Jesús García-Valdés; Georgina B Gurrola; Gail A Robertson; Lourival D Possani
Mapping the receptor site for ergtoxin, a specific blocker of ERG channels.
FEBS letters 2002;510(1-2):45-9.
2001: Miguel Corona; NORMA VALDEZ Cruz; Enrique Merino; Mario Zurita; Lourival D Possani
Genes and peptides from the scorpion Centruroides sculpturatus Ewing, that recognize Na(+)-channels.
Toxicon : official journal of the International Society on Toxinology 2001;39(12):1893-8.
2001: Cyril Goudet; Tania Ferrer; L Galàn; A Artiles; C F Batista; Lourival D Possani; J Alvarez; A Aneiros; Jan Tytgat
Characterization of two Bunodosoma granulifera toxins active on cardiac sodium channels.
British journal of pharmacology 2001;134(6):1195-206.
2001: J Garcia-Valdes; Fernando Z Zamudio; L Toro; Lourival D Possani; L D Possan
Slotoxin, alphaKTx1.11, a new scorpion peptide blocker of MaxiK channels that differentiates between alpha and alpha+beta (beta1 or beta4) complexes.
FEBS letters 2001;505(3):369-73.
2001: Marcella Rocchetti; Alessandra Besana; Georgina B Gurrola; Lourival D Possani; Antonio Zaza
Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential.
The Journal of physiology 2001;534(Pt 3):721-32.
2001: Andrea Frau; Marzia Pisciotta; G B Gurrola; Lourival D Possani; Gianfranco Prestipino
Synthetic undecapeptide (NTX10-20) of noxiustoxin blocks completely the I(A) potassium currents of cerebellum granular cells.
European biophysics journal : EBJ 2001;29(8):569-73.
2001: Mózes Péter; Zoltán Varga; Péter Hajdu; Rezso Gáspár; Sándor Damjanovich; E Horjales; Lourival D Possani; György Panyi
Effects of toxins Pi2 and Pi3 on human T lymphocyte Kv1.3 channels: the role of Glu7 and Lys24.
The Journal of membrane biology 2001;179(1):13-25.
2000: Cesar V F Batista; Froylan Gómez-Lagunas; Sylvia Lucas; Lourival D Possani
Tc1, from Tityus cambridgei, is the first member of a new subfamily of scorpion toxin that blocks K(+)-channels.
FEBS letters 2000;486(2):117-20.
2000: Mózes Péter; Péter Hajdu; Zoltán Varga; Sándor Damjanovich; Lourival D Possani; György Panyi; Rezso Gáspár
Blockage of human T lymphocyte Kv1.3 channels by Pi1, a novel class of scorpion toxin.
Biochemical and biophysical research communications 2000;278(1):34-7.
2000: Marzia Pisciotta; F I Coronas; C Bloch; Gianfranco Prestipino; Lourival D Possani
Fast K(+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom.
Biochimica et biophysica acta 2000;1468(1-2):203-12.
2000: Lourival D Possani; Enrique Merino; Miguel Corona; Francisco Bolivar; Baltazar Becerril
Peptides and genes coding for scorpion toxins that affect ion-channels.
Biochimie 2000;82(9-10):861-8.
2000: A Scaloni; C Bottiglieri; L Ferrara; Miguel Corona; Georgina B Gurrola; Cesar V F Batista; Enzo Wanke; Lourival D Possani
Disulfide bridges of ergtoxin, a member of a new sub-family of peptide blockers of the ether-a-go-go-related K+ channel.
FEBS letters 2000;479(3):156-7.
2000: A Torres-Larios; Georgina B Gurrola; Fernando Z Zamudio; Lourival D Possani
Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus.
European journal of biochemistry / FEBS 2000;267(16):5023-31.
2000: R Conde; Fernando Z Zamudio; M H Rodríguez; Lourival D Possani
Scorpine, an anti-malaria and anti-bacterial agent purified from scorpion venom.
FEBS letters 2000;471(2-3):165-8.
2000: Yamileth Angulo; Timoteo Olamendi-Portugal; Lourival D Possani; Bruno Lomonte
Isolation and characterization of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a new Lys49 phospholipase A2 homologue.
The international journal of biochemistry & cell biology 2000;32(1):63-71.
1999: Muriel DELEPIERRE; Ada Prochnicka-Chalufour; J Boisbouvier; Lourival D Possani
Pi7, an orphan peptide from the scorpion Pandinus imperator: a 1H-NMR analysis using a nano-NMR Probe.
Biochemistry 1999;38(51):16756-65.
1999: R Conde; Fernando Z Zamudio; Baltazar Becerril; Lourival D Possani
Phospholipin, a novel heterodimeric phospholipase A2 from Pandinus imperator scp6pion venom.
FEBS letters 1999;460(3):447-50.
1999: Jan Tytgat; K George Chandy; M L Garcia; George A Gutman; Marie-France Martin-Eauclaire; Jurg van der Walt; Lourival D Possani
A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies.
Trends in pharmacological sciences 1999;20(11):444-7.
1999: Barbara Selisko; A F Licea; Baltazar Becerril; Fernando Z Zamudio; Lourival D Possani; Eduardo Horjales
Antibody BCF2 against scorpion toxin Cn2 from Centuroides noxius Hoffmann: primary structure and three-dimensional model as free Fv fragment and complexed with its antigen.
Proteins 1999;37(1):130-43.
1999: E S Calderon-Aranda; Barbara Selisko; E J York; Georgina B Gurrola; J M Stewart; Lourival D Possani
Mapping of an epitope recognized by a neutralizing monoclonal antibody specific to toxin Cn2 from the scorpion Centruroides noxius, using discontinuous synthetic peptides.
European journal of biochemistry / FEBS 1999;264(3):746-55.
1999: Lourival D Possani; Baltazar Becerril; Muriel DELEPIERRE; J Tytgat
Scorpion toxins specific for Na+-channels.
European journal of biochemistry / FEBS 1999;264(2):287-300.
1999: Gina D'Suze; Fernando Z Zamudio; Froylan Gómez-Lagunas; Lourival D Possani
A novel K+ channel blocking toxin from Tityus discrepans scorpion venom.
FEBS letters 1999;456(1):146-8.
1999: Georgina B Gurrola; Barbara Rosati; Marcella Rocchetti; G Pimienta; Antonio Zaza; Annarosa Arcangeli; Massimo Olivotto; Lourival D Possani; Enzo Wanke
A toxin to nervous, cardiac, and endocrine ERG K+ channels isolated from Centruroides noxius scorpion venom.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(8):953-62.
1999: Alessandro Pintar; Lourival D Possani; Muriel DELEPIERRE
Solution structure of toxin 2 from centruroides noxius Hoffmann, a beta-scorpion neurotoxin acting on sodium channels.
Journal of molecular biology 1999;287(2):359-67.
1999: M Ottolia; E Babini; P Gazzotti; Lourival D Possani; Gianfranco Prestipino
Reconstitution of a voltage and calcium dependent potassium channel from rat cerebellum.
Brain research 1999;815(2):410-3.
1999: Cesar V F Batista; L R da Silva; Antonio Sebben; A Scaloni; L Ferrara; G R Paiva; Timoteo Olamendi-Portugal; Lourival D Possani; Carlos Bloch
Antimicrobial peptides from the Brazilian frog Phyllomedusa distincta.
Peptides 1999;20(6):679-86.
1998: Jan Tytgat; T Debont; K Rostoll; Gert J Müller; Fons Verdonck; P Daenens; Jurg van der Walt; Lourival D Possani
Purification and partial characterization of a 'short' insectotoxin-like peptide from the venom of the scorpion Parabuthus schlechteri.
FEBS letters 1998;441(3):387-91.
1998: Lourival D Possani; Mario Zurita; Muriel DELEPIERRE; F H Hernández; M H Rodríguez
From noxiustoxin to Shiva-3, a peptide toxic to the sporogonic development of Plasmodium berghei.
Toxicon : official journal of the International Society on Toxinology 1998;36(11):1683-92.
1998: Muriel DELEPIERRE; Ada Prochnicka-Chalufour; Lourival D Possani
1H NMR structural analysis of novel potassium blocking toxins using a nano-NMR probe.
Toxicon : official journal of the International Society on Toxinology 1998;36(11):1599-608.
1998: J Boisbouvier; Ada Prochnicka-Chalufour; A R Nieto; J A Torres; N Nanard; Mario H Rodriguez; Lourival D Possani; Muriel DELEPIERRE
Structural information on a cecropin-like synthetic peptide, Shiva-3 toxic to the sporogonic development of Plasmodium berghei.
European journal of biochemistry / FEBS 1998;257(1):263-73.
1998: F Martínez; Carlos Muñoz-Garay; Georgina B Gurrola; Alberto Darszon; Lourival D Possani; Baltazar Becerril
Site directed mutants of Noxiustoxin reveal specific interactions with potassium channels.
FEBS letters 1998;429(3):381-4.
1998: Barbara Selisko; C Garcia; Baltazar Becerril; Froylan Gómez-Lagunas; C Garay; Lourival D Possani
Cobatoxins 1 and 2 from Centruroides noxius Hoffmann constitute a subfamily of potassium-channel-blocking scorpion toxins.
European journal of biochemistry / FEBS 1998;254(3):468-79.
1998: Timoteo Olamendi-Portugal; Froylan Gómez-Lagunas; Georgina B Gurrola; Lourival D Possani
Two similar peptides from the venom of the scorpion Pandinus imperator, one highly effective blocker and the other inactive on K+ channels.
Toxicon : official journal of the International Society on Toxinology 1998;36(5):759-70.
1998: Héctor H Valdivia; Lourival D Possani
Peptide toxins as probes of ryanodine receptor structure and function.
Trends in cardiovascular medicine 1998;8(3):111-8.
1998: Mózes Péter; Zoltán Varga; György Panyi; László Bene; Sándor Damjanovich; Carlo Pieri; Lourival D Possani; Rezso Gáspár
Pandinus imperator scorpion venom blocks voltage-gated K+ channels in human lymphocytes.
Biochemical and biophysical research communications 1998;242(3):621-5.
1998: Marzia Pisciotta; M Ottolia; Lourival D Possani; Gianfranco Prestipino
A novel toxin form the scorpion Androctonus australis blocks Shaker K+ channels expressed in Xenopus oocytes.
Biochemical and biophysical research communications 1998;242(2):287-91.
1998: Marzia Pisciotta; F I Coronas; Lourival D Possani; Gianfranco Prestipino
The Androctonus australis garzoni scorpion venom contains toxins that selectively affect voltage-dependent K(+)-channels in cerebellum granular cells.
European biophysics journal : EBJ 1998;27(1):69-73.
1997: R Ben Khalifa; Maria Stankiewicz; Marcel Pelhate; S E Serrano-Hernandez; Lourival D Possani; H Hinkel; Dietrich Mebs
Action of babycurus-toxin 1 from the east African scorpion Babycurus centrurimorphus on the isolated cockroach giant axon.
Toxicon : official journal of the International Society on Toxinology 1997;35(7):1069-80.
1997: Baltazar Becerril; S Marangoni; Lourival D Possani
Toxins and genes isolated from scorpions of the genus Tityus.
Toxicon : official journal of the International Society on Toxinology 1997;35(6):821-35.
1997: Fernando Z Zamudio; R Conde; C Arévalo; Baltazar Becerril; B M Martin; Héctor H Valdivia; Lourival D Possani
The mechanism of inhibition of ryanodine receptor channels by imperatoxin I, a heterodimeric protein from the scorpion Pandinus imperator.
The Journal of biological chemistry 1997;272(18):11886-94.
1997: Fernando Z Zamudio; Georgina B Gurrola; C Arévalo; R Sreekumar; Jeffery W Walker; Héctor H Valdivia; Lourival D Possani
Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors.
FEBS letters 1997;405(3):385-9.
1997: Muriel DELEPIERRE; Ada Prochnicka-Chalufour; Lourival D Possani
A novel potassium channel blocking toxin from the scorpion Pandinus imperator: A 1H NMR analysis using a nano-NMR probe.
Biochemistry 1997;36(9):2649-58.
1997: C García; Baltazar Becerril; Barbara Selisko; Muriel DELEPIERRE; Lourival D Possani
Isolation, characterization and comparison of a novel crustacean toxin with a mammalian toxin from the venom of the scorpion Centruroides noxius Hoffmann.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1997;116(3):315-22.
1997: Froylan Gómez-Lagunas; Timoteo Olamendi-Portugal; Lourival D Possani
Block of ShakerB K+ channels by Pi1, a novel class of scorpion toxin.
FEBS letters 1997;400(2):197-200.
1996: Barbara Selisko; C Garcia; Baltazar Becerril; Muriel DELEPIERRE; Lourival D Possani
An insect-specific toxin from Centruroides noxius Hoffmann. cDNA, primary structure, three-dimensional model and electrostatic surface potentials in comparison with other toxin variants.
European journal of biochemistry / FEBS 1996;242(2):235-42.
1996: F Martinez; Baltazar Becerril; Georgina B Gurrola; Brian M Martin; Lourival D Possani
Synthesis and expression of the gene coding for noxiustoxin, a K+ channel-blocking peptide from the venom of the scorpion Centruroides noxius.
Toxicon : official journal of the International Society on Toxinology 1996;34(11-12):1413-9.
1996: A R Nieto; G B Gurrola; L Vaca; Lourival D Possani
Noxiustoxin 2, a novel K+ channel blocking peptide from the venom of the scorpion Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1996;34(8):913-22.
1996: A F Licea; Baltazar Becerril; Lourival D Possani
Fab fragments of the monoclonal antibody BCF2 are capable of neutralizing the whole soluble venom from the scorpion Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1996;34(8):843-7.
1996: Froylan Gómez-Lagunas; Timoteo Olamendi-Portugal; F Z Zamudio; Lourival D Possani
Two novel toxins from the venom of the scorpion Pandinus imperator show that the N-terminal amino acid sequence is important for their affinities towards Shaker B K+ channels.
The Journal of membrane biology 1996;152(1):49-56.
1996: Fernando Z Zamudio; K M Wolf; Brian M Martin; Lourival D Possani; Vincent A Chiappinelli
Two novel alpha-neurotoxins isolated from the taipan snake, Oxyuranus scutellatus, exhibit reduced affinity for nicotinic acetylcholine receptors in brain and skeletal muscle.
Biochemistry 1996;35(24):7910-6.
1996: M Nobile; F Noceti; Gianfranco Prestipino; Lourival D Possani
Helothermine, a lizard venom toxin, inhibits calcium current in cerebellar granules.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1996;110(1):15-20.
1996: Gina D'Suze; F Corona; Lourival D Possani; Carlos Sevcik
High performance liquid chromatography purification and amino acid sequence of toxins from the muscarinic fraction of Tityus discrepans scorpion venom.
Toxicon : official journal of the International Society on Toxinology 1996;34(5):591-8.
1996: Timoteo Olamendi-Portugal; Froylan Gómez-Lagunas; Georgina B Gurrola; Lourival D Possani
A novel structural class of K+-channel blocking toxin from the scorpion Pandinus imperator.
The Biochemical journal 1996;315 ( Pt 3)():977-81.
1996: L Vaca; A Licea; Lourival D Possani
Modulation of cell membrane potential in cultured vascular endothelium.
The American journal of physiology 1996;270(3 Pt 1):C819-24.
1996: M Corona; Mario Zurita; Lourival D Possani; Baltazar Becerril
Cloning and characterization of the genomic region encoding toxin IV-5 from the scorpion Tityus serrulatus Lutz and Mello.
Toxicon : official journal of the International Society on Toxinology 1996;34(2):251-6.
1996: M Dehesa-Dávila; A N Ramírez; F Z Zamudio; G Gurrola-Briones; A Liévano; Alberto Darszon; Lourival D Possani
Structural and functional comparison of toxins from the venom of the scorpions Centruroides infamatus infamatus, Centruroides limpidus limpidus and Centruroides noxius.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1996;113(2):331-9.
1996: Baltazar Becerril; M Corona; F I Coronas; Fernando Z Zamudio; E S Calderon-Aranda; Paul Fletcher; Brian M Martin; Lourival D Possani
Toxic peptides and genes encoding toxin gamma of the Brazilian scorpions Tityus bahiensis and Tityus stigmurus.
The Biochemical journal 1996;313 ( Pt 3)():753-60.
1995: M Dauplais; Bernard Gilquin; Lourival D Possani; G Gurrola-Briones; Christian Roumestand; André Ménez
Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins.
Biochemistry 1995;34(51):16563-73.
1995: Georgina B Gurrola; Lourival D Possani
Structural and functional features of noxiustoxin: a K+ channel blocker.
Biochemistry and molecular biology international 1995;37(3):527-35.
1995: F Noceti; A N Ramírez; Lourival D Possani; Gianfranco Prestipino
Characterization of a voltage-dependent potassium channel in squid Schwann cells reconstituted in planar lipid bilayers.
Glia 1995;15(1):33-42.
1995: A Vazquez; J V Tapia; W K Eliason; Brian M Martin; F Lebreton; Muriel DELEPIERRE; Lourival D Possani; Baltazar Becerril
Cloning and characterization of the cDNAs encoding Na+ channel-specific toxins 1 and 2 of the scorpion Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1995;33(9):1161-70.
1995: E S Calderon-Aranda; Timoteo Olamendi-Portugal; Lourival D Possani
The use of synthetic peptides can be a misleading approach to generate vaccines against scorpion toxins.
Vaccine 1995;13(13):1198-206.
1995: Rezso Gáspár; László Bene; Sándor Damjanovich; C Muñoz-Garay; E S Calderon-Aranda; Lourival D Possani
Beta-scorpion toxin 2 from Centruroides noxius blocks voltage-gated K+ channels in human lymphocytes.
Biochemical and biophysical research communications 1995;213(2):419-23.
1995: P Hérion; G Gurrola-Briones; M Del Rocío Sánchez; R Saavedra; Lourival D Possani
Monoclonal antibodies against noxiustoxin.
Hybridoma 1995;14(3):247-51.
1994: M Dehesa-Dávila; Brian M Martin; M Nobile; Gianfranco Prestipino; Lourival D Possani
Isolation of a toxin from Centruroides infamatus infamatus Koch scorpion venom that modifies Na+ permeability on chick dorsal root ganglion cells.
Toxicon : official journal of the International Society on Toxinology 1994;32(12):1487-93.
1994: Héctor H Valdivia; Brian M Martin; A N Ramírez; Paul Fletcher; Lourival D Possani
Isolation and pharmacological characterization of four novel Na+ channel-blocking toxins from the scorpion Centruroides noxius Hoffmann.
Journal of biochemistry 1994;116(6):1383-91.
1994: Brian M Martin; A N Ramirez; Georgina B Gurrola; M Nobile; Gianfranco Prestipino; Lourival D Possani
Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch.
The Biochemical journal 1994;304 ( Pt 1)():51-6.
1994: M D Fletcher; Lourival D Possani; Paul Fletcher
Morphological studies by light and electron microscopy of pancreatic acinar cells under the effect of Tityus serrulatus venom.
Cell and tissue research 1994;278(2):255-64.
1994: F Lebreton; Muriel DELEPIERRE; A N Ramírez; C Balderas; Lourival D Possani
Primary and NMR three-dimensional structure determination of a novel crustacean toxin from the venom of the scorpion Centruroides limpidus limpidus Karsch.
Biochemistry 1994;33(37):11135-49.
1994: M Dehesa-Dávila; Lourival D Possani
Scorpionism and serotherapy in Mexico.
Toxicon : official journal of the International Society on Toxinology 1994;32(9):1015-8.
1994: Georgina B Gurrola; G Moreno-Hagelsieb; Fernando Z Zamudio; M García; X Soberon; Lourival D Possani
The disulfide bridges of toxin 2 from the scorpion Centruroides noxius Hoffmann and its three-dimensional structure calculated using the coordinates of variant 3 from Centruroides sculpturatus.
FEBS letters 1994;347(1):59-62.
1994: M Nobile; V Magnelli; L Lagostena; J Mochca-Morales; Lourival D Possani; Gianfranco Prestipino
The toxin helothermine affects potassium currents in newborn rat cerebellar granule cells.
The Journal of membrane biology 1994;139(1):49-55.
1994: A N Ramírez; Brian M Martin; Georgina B Gurrola; Lourival D Possani
Isolation and characterization of a novel toxin from the venom of the scorpion Centruroides limpidus limpidus Karsch.
Toxicon : official journal of the International Society on Toxinology 1994;32(4):479-90.
1993: Baltazar Becerril; M Corona; M C Mejía; Brian M Martin; S Lucas; Francisco Bolivar; Lourival D Possani
The genomic region encoding toxin gamma from the scorpion Tityus serrulatus contains an intron.
FEBS letters 1993;335(1):6-8.
1993: Baltazar Becerril; A Vázquez; C García; M Corona; Francisco Bolivar; Lourival D Possani
Cloning and characterization of cDNAs that code for Na(+)-channel-blocking toxins of the scorpion Centruroides noxius Hoffmann.
Gene 1993;128(2):165-71.
1993: L Vaca; G B Gurrola; Lourival D Possani; Diana L Kunze
Blockade of a KCa channel with synthetic peptides from noxiustoxin: a K+ channel blocker.
The Journal of membrane biology 1993;134(2):123-9.
1993: A Vázquez; Baltazar Becerril; Brian M Martin; Fernando Z Zamudio; Francisco Bolívar; Lourival D Possani
Primary structure determination and cloning of the cDNA encoding toxin 4 of the scorpion Centruroides noxius Hoffmann.
FEBS letters 1993;320(1):43-6.
1993: E S Calderon-Aranda; D Hozbor; Lourival D Possani
Neutralizing capacity of murine sera induced by different antigens of scorpion venom.
Toxicon : official journal of the International Society on Toxinology 1993;31(3):327-37.
1992: Lourival D Possani; Brian M Martin; A Yatani; J Mochca-Morales; Fernando Z Zamudio; Georgina B Gurrola; A M Brown
Isolation and physiological characterization of taicatoxin, a complex toxin with specific effects on calcium channels.
Toxicon : official journal of the International Society on Toxinology 1992;30(11):1343-64.
1992: Héctor H Valdivia; Brian M Martin; L Escobar; Lourival D Possani
Noxiustoxin and leiurutoxin III, two homologous peptide toxins with binding properties to synaptosomal membrane K+ channels.
Biochemistry international 1992;27(6):953-62.
1992: Paul Fletcher; M D Fletcher; Lourival D Possani
Characteristics of pancreatic exocrine secretion produced by venom from the Brazilian scorpion, Tityus serrulatus.
European journal of cell biology 1992;58(2):259-70.
1992: Lourival D Possani; J Mochca-Morales; J Amezcua; Brian M Martin; Gianfranco Prestipino; M Nobile
Anionic currents of chick sensory neurons are affected by a phospholipase A2 purified from the venom of the taipan snake.
Biochimica et biophysica acta 1992;1134(3):210-6.
1992: F Zamudio; R Saavedra; Brian M Martin; G Gurrola-Briones; P Hérion; Lourival D Possani
Amino acid sequence and immunological characterization with monoclonal antibodies of two toxins from the venom of the scorpion Centruroides noxius Hoffmann.
European journal of biochemistry / FEBS 1992;204(1):281-92.
1991: Lourival D Possani; Brian M Martin; M D Fletcher; Paul Fletcher
Discharge effect on pancreatic exocrine secretion produced by toxins purified from Tityus serrulatus scorpion venom.
The Journal of biological chemistry 1991;266(5):3178-85.
1990: Margaret Stanfield; William Schilling; Lourival D Possani; Diana L Kunze
Bradykinin-induced potassium current in cultured bovine aortic endothelial cells.
The Journal of membrane biology 1990;116(3):227-38.
1990: G A Ramírez; Paul Fletcher; Lourival D Possani
Characterization of the venom from Crotalus molossus nigrescens Gloyd (black tail rattlesnake): isolation of two proteases.
Toxicon : official journal of the International Society on Toxinology 1990;28(3):285-97.
1990: J Mochca-Morales; Brian M Martin; Lourival D Possani
Isolation and characterization of helothermine, a novel toxin from Heloderma horridum horridum (Mexican beaded lizard) venom.
Toxicon : official journal of the International Society on Toxinology 1990;28(3):299-309.
1989: Gianfranco Prestipino; Héctor H Valdivia; A Liévano; Alberto Darszon; A N Ramírez; Lourival D Possani
Purification and reconstitution of potassium channel proteins from squid axon membranes.
FEBS letters 1989;250(2):570-4.
1989: G B Gurrola; R Molinar-Rode; M Sitges; A Bayon; Lourival D Possani
Synthetic peptides corresponding to the sequence of noxiustoxin indicate that the active site of this K+ channel blocker is located on its amino-terminal portion.
Journal of neural transmission 1989;77(1):11-20.
1989: Glenn E Kirsch; A Skattebøl; Lourival D Possani; Arthur M Brown
Modification of Na channel gating by an alpha scorpion toxin from Tityus serrulatus.
The Journal of general physiology 1989;93(1):67-83.
1988: A Yatani; Glenn E Kirsch; Lourival D Possani; Arthur M Brown
Effects of New World scorpion toxins on single-channel and whole cell cardiac sodium currents.
The American journal of physiology 1988;254(3 Pt 2):H443-51.
1988: Héctor H Valdivia; J S Smith; B M Martin; Roberto Coronado; Lourival D Possani
Charybdotoxin and noxiustoxin, two homologous peptide inhibitors of the K+ (Ca2+) channel.
FEBS letters 1988;226(2):280-4.
1988: A N Ramírez; Georgina B Gurrola; Brian M Martin; Lourival D Possani
Isolation of several toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1988;26(9):773-83.
1988: Brian M Martin; Emilio Carbone; A Yatani; A M Brown; A N Ramírez; Georgina B Gurrola; Lourival D Possani
Amino acid sequence and physiological characterization of toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1988;26(9):785-94.
1988: A C Alagón; H S Guzmán; Brian M Martin; A N Ramírez; Emilio Carbone; Lourival D Possani
Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch.
Comparative biochemistry and physiology. B, Comparative biochemistry 1988;89(1):153-61.
1987: Arthur M Brown; A Yatani; A E Lacerda; G B Gurrola; Lourival D Possani
Neurotoxins that act selectively on voltage-dependent cardiac calcium channels.
Circulation research 1987;61(4 Pt 2):I6-9.
1982: A C Alagón; M E Maldonado; J Z Juliá; C R Sánchez; Lourival D Possani
Venom from two sub-species of Heloderma horridum (Mexican beaded lizard): general characterization and purification of N-benzoyl-L-arginine ethyl ester hydrolase.
Toxicon : official journal of the International Society on Toxinology 1982;20(2):463-75.
1980: A C Alagón; R R Molinar; Lourival D Possani; Paul Fletcher; John E Cronan; J Z Julia
Venom from the snake Bothrops asper Garman. Purification and characterization of three phospholipases A2.
The Biochemical journal 1980;185(3):695-704.
1980: M A Dent; Lourival D Possani; G A Ramírez; Paul Fletcher
Purification and characterization of two mammalian toxins from the venom of the Mexican scorpion Centruroides noxius Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1980;18(3):343-50.
1980: Lourival D Possani; Paul Fletcher; A B Alagón; A C Alagón; J Z Juliá
Purification and characterization of a mammalian toxin from venom of the Mexican scorpion, Centruroides limpidus tecomanus Hoffmann.
Toxicon : official journal of the International Society on Toxinology 1980;18(2):175-83.