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Anthony Postle

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Marcus K Dymond; Charlotte V Hague; Anthony D Postle; George S Attard
An in vivo ratio control mechanism for phospholipid homeostasis: evidence from lipidomic studies.
Victoria Goss; Alan N Hunt; Anthony D Postle
Regulation of lung surfactant phospholipid synthesis and metabolism.
Gavin W Sewell; Philip J Smith; Roser Vega; Ann P Walker; Jacek Bielawski; Stuart L Bloom; Victoria Goss; Xianlin Han; Yusuf A Hannun; Grielof Koster; Anthony D Postle; Farooq Z Rahman; Anthony W Segal
Lipidomic profiling in Crohn's disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition.

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All Publications

2013: Marcus K Dymond; Charlotte V Hague; Anthony D Postle; George S Attard
An in vivo ratio control mechanism for phospholipid homeostasis: evidence from lipidomic studies.
Journal of the Royal Society, Interface / the Royal Society 2013;10(80):20120854.
2013: Victoria Goss; Alan N Hunt; Anthony D Postle
Regulation of lung surfactant phospholipid synthesis and metabolism.
Biochimica et biophysica acta 2013;1831(2):448-58.
2012: Gavin W Sewell; Philip J Smith; Roser Vega; Ann P Walker; Jacek Bielawski; Stuart L Bloom; Victoria Goss; Xianlin Han; Yusuf A Hannun; Grielof Koster; Anthony D Postle; Farooq Z Rahman; Anthony W Segal
Lipidomic profiling in Crohn's disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition.
The international journal of biochemistry & cell biology 2012;44(11):1839-46.
2012: Anthony D Postle
Lipidomics.
Current opinion in clinical nutrition and metabolic care 2012;15(2):127-33.
2011: Anthony D Postle; Grielof Koster; Howard W Clark; Neil G Henderson; Alan N Hunt
Analysis of lung surfactant phosphatidylcholine metabolism in transgenic mice using stable isotopes.
Chemistry and physics of lipids 2011;164(6):549-55.
2011: Christopher J Pynn; Neil G Henderson; Howard Clark; Grielof Koster; Wolfgang Bernhard; Anthony D Postle
Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo.
Journal of lipid research 2011;52(2):399-407.
2010: David A Todd; Michael J Marsh; Anne George; Neil G Henderson; Heather Barr; Seby Sebastian; Graeme Clark; Grielof Koster; Howard W Clark; Anthony D Postle
Surfactant phospholipids, surfactant proteins, and inflammatory markers during acute lung injury in children.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2010;11(1):82-91.
2009: Marco Paoli; Michela Rigoni; Grielof Koster; Ornella Rossetto; Cesare Montecucco; Anthony D Postle
Mass spectrometry analysis of the phospholipase A(2) activity of snake pre-synaptic neurotoxins in cultured neurons.
Journal of neurochemistry 2009;111(3):737-44.
2008: Marcus Dymond; George S Attard; Anthony D Postle
Testing the hypothesis that amphiphilic antineoplastic lipid analogues act through reduction of membrane curvature elastic stress.
Journal of the Royal Society, Interface / the Royal Society 2008;5(28):1371-86.
2008: Alan N Hunt; Marita Macken; Grielof Koster; Janice A Kohler; Anthony D Postle
Diclofenac mediated derangement of neuroblastoma cell lipidomic profiles is accompanied by increased phosphatidylcholine biosynthesis.
Advances in enzyme regulation 2008;48():74-87.
2007: Wolfgang Bernhard; Andreas Schmiedl; Grielof Koster; Sandra Orgeig; Christa Acevedo; Christian F Poets; Anthony D Postle
Developmental changes in rat surfactant lipidomics in the context of species variability.
Pediatric pulmonology 2007;42(9):794-804.
2007: Anthony D Postle; David C Wilton; Alan N Hunt; George S Attard
Probing phospholipid dynamics by electrospray ionisation mass spectrometry.
Progress in lipid research 2007;46(3-4):200-24.
2007: Helen Holt; SH Wild; Anthony D Postle; J Zhang; Grielof Koster; M Umpleby; F Shojaee-Moradie; KC Dewbury; Peter J Wood; David I W Phillips; Christopher D Byrne
Cortisol clearance and associations with insulin sensitivity, body fat and fatty liver in middle-aged men.
Diabetologia 2007;50(5):1024-32.
2006: Alan N Hunt; Anthony D Postle
Mass spectrometry determination of endonuclear phospholipid composition and dynamics.
Methods (San Diego, Calif.) 2006;39(2):104-11.
2006: Anthony D Postle; Linda W Gonzales; Wolfgang Bernhard; Graeme Clark; Marye H Godinez; Rodolfo I Godinez; Philip L Ballard
Lipidomics of cellular and secreted phospholipids from differentiated human fetal type II alveolar epithelial cells.
Journal of lipid research 2006;47(6):1322-31.
2006: Natalie J Miller; Anthony D Postle; Sandra Orgeig; Grielof Koster; Christopher B Daniels
The composition of pulmonary surfactant from diving mammals.
Respiratory physiology & neurobiology 2006;152(2):152-68.
2006: Masahiro Goto; Karen Piper Hanley; Josep Marcos; Peter J Wood; Sarah Wright; Anthony D Postle; Iain T Cameron; J Ian Mason; David I Wilson; Neil A Hanley
In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development.
The Journal of clinical investigation 2006;116(4):953-60.
2005: Michela Rigoni; Paola Caccin; Stephen Gschmeissner; Grielof Koster; Anthony D Postle; Ornella Rossetto; Giampietro Schiavo; Cesare Montecucco
Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures.
Science (New York, N.Y.) 2005;310(5754):1678-80.
2005: Carol J Lang; Anthony D Postle; Sandra Orgeig; Fred Possmayer; Wolfgang Bernhard; Amiya Kumar Panda; Klaus D Jürgens; William K Milsom; Kaushik Nag; Christopher B Daniels
Dipalmitoylphosphatidylcholine is not the major surfactant phospholipid species in all mammals.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(5):R1426-39.
2005: Natalie J Miller; Anthony D Postle; Samuel Schürch; W Michael Schoel; Christopher B Daniels; Sandra Orgeig
The development of the pulmonary surfactant system in California sea lions.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2005;141(2):191-9.
2004: Alan N Hunt; James G Alb; Grielof Koster; Anthony D Postle; Vytas A Bankaitis
Use of mass spectrometry-based lipidomics to probe PITPalpha (phosphatidylinositol transfer protein alpha) function inside the nuclei of PITPalpha+/+ and PITPalpha-/- cells.
Biochemical Society transactions 2004;32(Pt 6):1063-5.
2004: Alan N Hunt; H C Fenn; Graeme Clark; Marcia M Wright; Anthony D Postle; Christopher R McMaster
Lipidomic analysis of the molecular specificity of a cholinephosphotransferase in situ.
Biochemical Society transactions 2004;32(Pt 6):1060-2.
2004: Anthony D Postle; Heike Dombrowsky; H Clarke; C J Pynn; Grielof Koster; Alan N Hunt
Mass spectroscopic analysis of phosphatidylinositol synthesis using 6-deuteriated-myo-inositol: comparison of the molecular specificities and acyl remodelling mechanisms in mouse tissues and cultured cells.
Biochemical Society transactions 2004;32(Pt 6):1057-9.
2004: Alan N Hunt; Alison Skippen; Grielof Koster; Anthony D Postle; Shamshad Cockcroft
Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha.
Biochimica et biophysica acta 2004;1686(1-2):50-60.
2004: Graham C Burdge; Anthony D Postle
Selective changes to phosphatidylcholine and phosphatidylethanolamine molecular species in the developing fetal guinea pig liver and plasma.
Reproduction, nutrition, development 2004;44(6):571-82.
2004: Helen A Rodway; Alan N Hunt; Janice A Kohler; Anthony D Postle; Karen A Lillycrop
Lysophosphatidic acid attenuates the cytotoxic effects and degree of peroxisome proliferator-activated receptor gamma activation induced by 15-deoxyDelta12,14-prostaglandin J2 in neuroblastoma cells.
The Biochemical journal 2004;382(Pt 1):83-91.
2004: Wolfgang Bernhard; Christopher J Pynn; Andreas Jaworski; Gunnar A Rau; Jens Hohlfeld; Joachim Freihorst; Christian F Poets; Dieter Stoll; Anthony D Postle
Mass spectrometric analysis of surfactant metabolism in human volunteers using deuteriated choline.
American journal of respiratory and critical care medicine 2004;170(1):54-8.
2004: Alan N Hunt; Anthony D Postle
Phosphatidylcholine biosynthesis inside the nucleus: is it involved in regulating cell proliferation?
Advances in enzyme regulation 2004;44():173-86.
2003: Samantha Kew; S Wells; Frank Thies; G P McNeill; P T Quinlan; Graeme Clark; Heike Dombrowsky; Anthony D Postle; Philip Calder
The effect of eicosapentaenoic acid on rat lymphocyte proliferation depends upon its position in dietary triacylglycerols.
The Journal of nutrition 2003;133(12):4230-8.
2003: Heike Dombrowsky; Graeme Clark; Gunnar A Rau; Wolfgang Bernhard; Anthony D Postle
Molecular species compositions of lung and pancreas phospholipids in the cftr(tm1HGU/tm1HGU) cystic fibrosis mouse.
Pediatric research 2003;53(3):447-54.
2002: Ann Mander; Simon Langton Hewer; Wolfgang Bernhard; John O Warner; Anthony D Postle
Altered phospholipid composition and aggregate structure of lung surfactant is associated with impaired lung function in young children with respiratory infections.
American journal of respiratory cell and molecular biology 2002;27(6):714-21.
2002: S Brooks; Graeme Clark; S M Wright; R J Trueman; Anthony D Postle; Andrew R Cossins; Norman Maclean
Electrospray ionisation mass spectrometric analysis of lipid restructuring in the carp (Cyprinus carpio L.) during cold acclimation.
The Journal of experimental biology 2002;205(Pt 24):3989-97.
2002: Linda W Gonzales; Susan H Guttentag; Kelly C Wade; Anthony D Postle; Philip L Ballard
Differentiation of human pulmonary type II cells in vitro by glucocorticoid plus cAMP.
American journal of physiology. Lung cellular and molecular physiology 2002;283(5):L940-51.
2002: Alan N Hunt; Graeme Clark; James R Neale; Anthony D Postle
A comparison of the molecular specificities of whole cell and endonuclear phosphatidylcholine synthesis.
FEBS letters 2002;530(1-3):89-93.
2001: Wolfgang Bernhard; Andreas Gebert; Gertrud Vieten; Gunnar A Rau; Jens Hohlfeld; Anthony D Postle; Joachim Freihorst
Pulmonary surfactant in birds: coping with surface tension in a tubular lung.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(1):R327-37.
2001: Wolfgang Bernhard; Anthony D Postle; Gunnar A Rau; Joachim Freihorst
Pulmonary and gastric surfactants. A comparison of the effect of surface requirements on function and phospholipid composition.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2001;129(1):173-82.
2001: Anthony D Postle; Emma Heeley; David C Wilton
A comparison of the molecular species compositions of mammalian lung surfactant phospholipids.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2001;129(1):65-73.
2001: Alan N Hunt; Graeme Clark; George S Attard; Anthony D Postle
Highly saturated endonuclear phosphatidylcholine is synthesized in situ and colocated with CDP-choline pathway enzymes.
The Journal of biological chemistry 2001;276(11):8492-9.
2000: S M Wright; P M Hockey; G Enhorning; P Strong; K B Reid; Stephen T Holgate; R Djukanovic; Anthony D Postle
Altered airway surfactant phospholipid composition and reduced lung function in asthma.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;89(4):1283-92.
2000: Emma Heeley; Jens Hohlfeld; Norbert Krug; Anthony D Postle
Phospholipid molecular species of bronchoalveolar lavage fluid after local allergen challenge in asthma.
American journal of physiology. Lung cellular and molecular physiology 2000;278(2):L305-11.
1999: Anthony D Postle; Ann Mander; K B Reid; J Y Wang; S M Wright; M Moustaki; John O Warner
Deficient hydrophilic lung surfactant proteins A and D with normal surfactant phospholipid molecular species in cystic fibrosis.
American journal of respiratory cell and molecular biology 1999;20(1):90-8.
1998: E Heeley; S Wright; D Wilton; Anthony D Postle
Molecular species of acidic phospholipids in human lung surfactant.
Biochemical Society transactions 1998;26(3):S227.
1998: S M Wright; Alan N Hunt; Anthony D Postle
Analysis of phosphatidic acid molecular species using mass spectrometry.
Biochemical Society transactions 1998;26(3):S226.
1998: Alan N Hunt; G C Burdge; S M Wright; Anthony D Postle
S phase depletion of nuclear CTP:choline phosphate cytidylyltransferase.
Biochemical Society transactions 1998;26(3):S222.
1998: G C Burdge; Anthony D Postle
Pregnancy-associated adaptations to hepatic phosphatidylcholine biosynthesis in the guinea-pig.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1998;119(2):265-72.
1997: Ann Mander; M Petrovic; S Wright; Emma Heeley; John O Warner; Anthony D Postle
Neutrophil phosphatidylcholine (PC) composition in cystic fibrosis (CF).
Biochemical Society transactions 1997;25(4):S593.
1997: Wolfgang Bernhard; H P Haagsman; Thomas Tschernig; Christian F Poets; Anthony D Postle; Martin van Eijk; Horst von der Hardt
Conductive airway surfactant: surface-tension function, biochemical composition, and possible alveolar origin.
American journal of respiratory cell and molecular biology 1997;17(1):41-50.
1997: Ann Mander; G Keenleyside; Anthony D Postle
Membrane phosphatidylcholine composition of human lymphocytes in neonates.
Biochemical Society transactions 1997;25(2):346S.
1996: Alan N Hunt; G C Burdge; Anthony D Postle
Phospholipid composition of neonatal guinea pig liver and plasma: effect of postnatal food restriction.
Lipids 1996;31(5):489-95.
1996: A C Jones; G C Burdge; J A Warner; Anthony D Postle; J O Warner
Ontogeny of circulating leucocytes in the fetal guinea pig.
Biology of the neonate 1996;70(2):108-15.
1995: G C Burdge; A Creaney; Anthony D Postle; David C Wilton
Mammalian secreted and cytosolic phospholipase A2 show different specificities for phospholipid molecular species.
The international journal of biochemistry & cell biology 1995;27(10):1027-32.
1995: Anthony D Postle; M D Al; G C Burdge; G Hornstra
The composition of individual molecular species of plasma phosphatidylcholine in human pregnancy.
Early human development 1995;43(1):47-58.
1995: G C Burdge; Anthony D Postle
Phospholipid molecular species composition of developing fetal guinea pig brain.
Lipids 1995;30(8):719-24.
1995: G C Burdge; Anthony D Postle
Effect of maternal ethanol consumption during pregnancy on the phospholipid molecular species composition of fetal guinea-pig brain, liver and plasma.
Biochimica et biophysica acta 1995;1256(3):346-52.
1995: Y M Heung; Anthony D Postle
The molecular selectivity of phospholipase D in HL60 granulocytes.
FEBS letters 1995;364(3):250-4.
1995: Y M Heung; Anthony D Postle
Substrate selectivity of phospholipase D in HL60 granulocytes: effects of fatty acid supplementation.
Biochemical Society transactions 1995;23(2):276S.
1995: Y M Heung; Anthony D Postle
Synthesis of phosphatidyl[3H]butanol molecular species by phospholipase D in HL60 granulocytes.
Biochemical Society transactions 1995;23(2):275S.
1994: G C Burdge; Alan N Hunt; Anthony D Postle
Mechanisms of hepatic phosphatidylcholine synthesis in adult rat: effects of pregnancy.
The Biochemical journal 1994;303 ( Pt 3)():941-7.
1994: M R Ashton; Anthony D Postle; D E Smith; M A Hall
Surfactant phosphatidylcholine composition during dexamethasone treatment in chronic lung disease.
Archives of disease in childhood 1994;71(2):F114-7.
1994: G C Burdge; A J Goodale; C M Hill; P J Halford; E J Lambert; Anthony D Postle; CJ Rolles
Plasma lipid concentrations in children with cystic fibrosis: the value of a high-fat diet and pancreatic supplementation.
The British journal of nutrition 1994;71(6):959-64.
1994: G C Burdge; Anthony D Postle
Hepatic phospholipid molecular species in the guinea pig. Adaptations to pregnancy.
Lipids 1994;29(4):259-64.
1994: Anthony D Postle; G C Burdge; M D Al
Molecular species composition of plasma phosphatidylcholine in human pregnancy.
World review of nutrition and dietetics 1994;75():109-11.
1993: G C Burdge; Frank Kelly; Anthony D Postle
Synthesis of phosphatidylcholine in guinea-pig fetal lung involves acyl remodelling and differential turnover of individual molecular species.
Biochimica et biophysica acta 1993;1166(2-3):251-7.
1993: G C Burdge; Frank Kelly; Anthony D Postle
Mechanisms of hepatic phosphatidylcholine synthesis in the developing guinea pig: contributions of acyl remodelling and of N-methylation of phosphatidylethanolamine.
The Biochemical journal 1993;290 ( Pt 1)():67-73.
1992: M C McElroy; Anthony D Postle; Frank Kelly
Catalase, superoxide dismutase and glutathione peroxidase activities of lung and liver during human development.
Biochimica et biophysica acta 1992;1117(2):153-8.
1992: G C Burdge; Frank Kelly; Anthony D Postle
Mechanisms of synthesis of polyunsaturated phosphatidylcholine molecular species by guinea pig liver.
Biochemical Society transactions 1992;20(3):299S.
1992: Alan N Hunt; AR Kinkaid; David C Wilton; Anthony D Postle
Phospholipase A2 specificities determined in mixed substrate vesicles using a combination of continuous fluorescence displacement and quantitative HPLC analyses.
Biochemical Society transactions 1992;20(3):298S.
1992: M R Ashton; Anthony D Postle; M A Hall; N C Austin; D E Smith; I C Normand
Turnover of exogenous artificial surfactant.
Archives of disease in childhood 1992;67(4 Spec No):383-7.
1992: M R Ashton; Anthony D Postle; M A Hall; S L Smith; Frank Kelly; I C Normand
Phosphatidylcholine composition of endotracheal tube aspirates of neonates and subsequent respiratory disease.
Archives of disease in childhood 1992;67(4 Spec No):378-82.
1991: P A Caesar; M C McElroy; Frank Kelly; I C Normand; Anthony D Postle
Mechanisms of phosphatidylcholine acyl remodeling by human fetal lung.
American journal of respiratory cell and molecular biology 1991;5(4):363-70.
1991: Alan N Hunt; Frank Kelly; Anthony D Postle
Developmental variation in whole human lung phosphatidylcholine molecular species: a comparison with guinea pig and rat.
Early human development 1991;25(3):157-71.
1991: G C Burdge; Frank Kelly; Anthony D Postle
The biosynthesis of molecular species of phosphatidylcholine in neonatal guinea pig liver.
Biochemical Society transactions 1991;19(2):113S.
1991: G C Burdge; Frank Kelly; Anthony D Postle
The biosynthesis of phosphatidylcholine molecular species in fetal and neonatal guinea pig lung.
Biochemical Society transactions 1991;19(2):112S.
1991: Alan N Hunt; A F Bellhouse; Frank Kelly; Anthony D Postle
Late gestation changes in rat tissue phosphatidylcholine composition.
Biochemical Society transactions 1991;19(2):111S.
1990: Alan N Hunt; C S Normand; Anthony D Postle
CTP:cholinephosphate cytidylyltransferase in human and rat lung: association in vitro with cytoskeletal actin.
Biochimica et biophysica acta 1990;1043(1):19-26.
1988: P A Caesar; S J Wilson; C S Normand; Anthony D Postle
A comparison of the specificity of phosphatidylcholine synthesis by human fetal lung maintained in either organ or organotypic culture.
The Biochemical journal 1988;253(2):451-7.
1985: Anthony D Postle; Alan N Hunt; I C Normand
The proteins of human lung surfactant.
Biochimica et biophysica acta 1985;837(3):305-13.