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Sovitj Pou

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Sovitj Pou; Erin W Riscoe; Keith W Wegmann; Rolf W Winter; J Stone Doggett; David J Hinrichs; Jane Xu Kelly; Yuexin Li; Aaron Nilsen; Michael K Riscoe
Sontochin as a guide to the development of drugs against chloroquine-resistant malaria.
John Weaver; Supatra Porasuphatana; Pei Tsai; Sovitj Pou; Linda Roman; Gerald M. Rosen
A comparative study of neuronal and inducible nitric oxide synthases: generation of nitric oxide, superoxide, and hydrogen peroxide.
Pei Tsai; Jeffrey M Marra; Sovitj Pou; Michael K Bowman; Gerald M. Rosen
Is there stereoselectivity in spin trapping superoxide by 5-tert-butoxycarbonyl-5-methyl-1-pyrroline N-oxide?

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2012: Sovitj Pou; Erin W Riscoe; Keith W Wegmann; Rolf W Winter; J Stone Doggett; David J Hinrichs; Jane Xu Kelly; Yuexin Li; Aaron Nilsen; Michael K Riscoe
Sontochin as a guide to the development of drugs against chloroquine-resistant malaria.
Antimicrobial agents and chemotherapy 2012;56(7):3475-80.
2005: John Weaver; Supatra Porasuphatana; Pei Tsai; Sovitj Pou; Linda Roman; Gerald M. Rosen
A comparative study of neuronal and inducible nitric oxide synthases: generation of nitric oxide, superoxide, and hydrogen peroxide.
Biochimica et biophysica acta 2005;1726(3):302-8.
2005: Pei Tsai; Jeffrey M Marra; Sovitj Pou; Michael K Bowman; Gerald M. Rosen
Is there stereoselectivity in spin trapping superoxide by 5-tert-butoxycarbonyl-5-methyl-1-pyrroline N-oxide?
The Journal of organic chemistry 2005;70(18):7093-7.
2005: Pei Tsai; John Weaver; Guan-Liang Cao; Sovitj Pou; Linda Roman; anatoly starkov; Gerald M. Rosen
L-arginine regulates neuronal nitric oxide synthase production of superoxide and hydrogen peroxide.
Biochemical pharmacology 2005;69(6):971-9.
2004: John Weaver; Pei Tsai; Sovitj Pou; Gerald M. Rosen
Superoxide dismutase versus ferricytochrome C: determining rate constants for the spin trapping of superoxide by cyclic nitrones.
The Journal of organic chemistry 2004;69(24):8423-8.
2004: Gerald M. Rosen; Aleksandra Beselman; Pei Tsai; Sovitj Pou; Colin Mailer; Kazuhiro Ichikawa; Bruce H Robinson; Robert Nielsen; Howard J Halpern; Alexander D. Mackerell
Influence of conformation on the EPR spectrum of 5,5-dimethyl-1-hydroperoxy-1-pyrrolidinyloxyl: a spin trapped adduct of superoxide.
The Journal of organic chemistry 2004;69(4):1321-30.
2003: Pei Tsai; Kazuhiro Ichikawa; Colin Mailer; Sovitj Pou; Howard J Halpern; Bruce H Robinson; Robert Nielsen; Gerald M. Rosen
Esters of 5-carboxyl-5-methyl-1-pyrroline N-oxide: a family of spin traps for superoxide.
The Journal of organic chemistry 2003;68(20):7811-7.
2003: K. Chul Kim; B C Lee; Sovitj Pou; D Ciccolella
Effects of activation of polymorphonuclear leukocytes on airway goblet cell mucin release in a co-culture system.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2003;52(6):258-62.
2002: Gerald M. Rosen; Pei Tsai; John Weaver; Supatra Porasuphatana; Linda Roman; anatoly starkov; Gary Fiskum; Sovitj Pou
The role of tetrahydrobiopterin in the regulation of neuronal nitric-oxide synthase-generated superoxide.
The Journal of biological chemistry 2002;277(43):40275-80.
2002: Gerald M. Rosen; Pei Tsai; Sovitj Pou
Mechanism of free-radical generation by nitric oxide synthase.
Chemical reviews 2002;102(4):1191-200.
2002: Supatra Porasuphatana; Pei Tsai; Sovitj Pou; Gerald M. Rosen
Perferryl complex of nitric oxide synthase: role in secondary free radical formation.
Biochimica et biophysica acta 2002;1569(1-3):111-6.
2001: Dennis J Stuehr; Sovitj Pou; Gerald M. Rosen
Oxygen reduction by nitric-oxide synthases.
The Journal of biological chemistry 2001;276(18):14533-6.
2001: Supatra Porasuphatana; Pei Tsai; Sovitj Pou; Gerald M. Rosen
Involvement of the perferryl complex of nitric oxide synthase in the catalysis of secondary free radical formation.
Biochimica et biophysica acta 2001;1526(1):95-104.
1999: Sovitj Pou; Pei Tsai; Supatra Porasuphatana; Howard J Halpern; Gadisetti V R Chandramouli; E D Barth; Gerald M. Rosen
Spin trapping of nitric oxide by ferro-chelates: kinetic and in vivo pharmacokinetic studies.
Biochimica et biophysica acta 1999;1427(2):216-26.
1999: Sovitj Pou; L Keaton; W Surichamorn; Gerald M. Rosen
Mechanism of superoxide generation by neuronal nitric-oxide synthase.
The Journal of biological chemistry 1999;274(14):9573-80.
1998: Y I Huang; W Surichamorn; Guan-Liang Cao; M Meng; Sovitj Pou; Gerald M. Rosen; T W Salcedo; Anne M Strimpler; CA Veale; Peter R Bernstein; C M Bonuccelli
Effect of trifluoromethyl ketone-based elastase inhibitors on neutrophil function in vitro.
Journal of leukocyte biology 1998;64(3):322-30.
1998: Gerald M. Rosen; Sovitj Pou; Howard J Halpern
In vivo detection of free radicals in real time by low-frequency electron paramagnetic resonance spectroscopy.
Methods in molecular biology (Clifton, N.J.) 1998;108():27-35.
1995: Sovitj Pou; P L Davis; G L Wolf; Gerald M. Rosen
Use of nitroxides as NMR contrast enhancing agents for joints.
Free radical research 1995;23(4):353-64.
1995: Sovitj Pou; A Bhan; Vishweshwar S Bhadti; S Y Wu; Ramachandra S Hosmane; Gerald M. Rosen
The use of fluorophore-containing spin traps as potential probes to localize free radicals in cells with fluorescence imaging methods.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(11):1085-90.
1995: Sovitj Pou; S Y Nguyen; T Gladwell; Gerald M. Rosen
Does peroxynitrite generate hydroxyl radical?
Biochimica et biophysica acta 1995;1244(1):62-8.
1995: C L Ramos; Sovitj Pou; Gerald M. Rosen
Effect of anti-inflammatory drugs on myeloperoxidase-dependent hydroxyl radical generation by human neutrophils.
Biochemical pharmacology 1995;49(8):1079-84.
1995: Gerald M. Rosen; Sovitj Pou; C L Ramos; M S Cohen; Bradley E Britigan
Free radicals and phagocytic cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(2):200-9.
1994: Sovitj Pou; D E Anderson; W Surichamorn; L L Keaton; ML Tod
Biological studies of a nitroso compound that releases nitric oxide upon illumination.
Molecular pharmacology 1994;46(4):709-15.
1994: Sovitj Pou; L Keaton; W Surichamorn; P Frigillana; Gerald M. Rosen
Can nitric oxide be spin trapped by nitrone and nitroso compounds?
Biochimica et biophysica acta 1994;1201(1):118-24.
1994: Sovitj Pou; C L Ramos; T Gladwell; E Renks; M Centra; D Young; M S Cohen; Gerald M. Rosen
A kinetic approach to the selection of a sensitive spin trapping system for the detection of hydroxyl radical.
Analytical biochemistry 1994;217(1):76-83.
1994: Gerald M. Rosen; Sovitj Pou; Bradley E Britigan; M S Cohen
Spin trapping of hydroxyl radicals in biological systems.
Methods in enzymology 1994;233():105-11.
1993: Sovitj Pou; Y I Huang; A Bhan; Vishweshwar S Bhadti; Ramachandra S Hosmane; S Y Wu; Guan-Liang Cao; Gerald M. Rosen
A fluorophore-containing nitroxide as a probe to detect superoxide and hydroxyl radical generated by stimulated neutrophils.
Analytical biochemistry 1993;212(1):85-90.
1993: Sovitj Pou; M R Gunther; W S Pou; Guan-Liang Cao; J M Bator; M S Cohen; R M Burch; Gerald M. Rosen
Effect of NPC 15669, an inhibitor of neutrophil recruitment and neutrophil-mediated inflammation, on neutrophil function in vitro.
Biochemical pharmacology 1993;45(10):2123-7.
1992: Sovitj Pou; W S Pou; D S Bredt; Solomon H Snyder; Gerald M. Rosen
Generation of superoxide by purified brain nitric oxide synthase.
The Journal of biological chemistry 1992;267(34):24173-6.
1992: PS Callery; B Subramanyam; Zhi-Min Yuan; Sovitj Pou; L A Geelhaar; Kevin A Reynolds
Isotopically sensitive regioselectivity in the oxidative deamination of a homologous series of diamines catalyzed by diamine oxidase.
Chemico-biological interactions 1992;85(1):15-26.
1992: K A Haberny; Sovitj Pou; C U Eccles
Potentiation of quinolinate-induced hippocampal lesions by inhibition of NO synthesis.
Neuroscience letters 1992;146(2):187-90.
1992: L A Bynoe; John D Gottsch; Sovitj Pou; Gerald M. Rosen
Light-dependent generation of superoxide from human erythrocytes.
Photochemistry and photobiology 1992;56(3):353-6.
1992: C L Ramos; Sovitj Pou; Bradley E Britigan; M S Cohen; Gerald M. Rosen
Spin trapping evidence for myeloperoxidase-dependent hydroxyl radical formation by human neutrophils and monocytes.
The Journal of biological chemistry 1992;267(12):8307-12.
1991: L A Bynoe; Sovitj Pou; John D Gottsch; Gerald M. Rosen
Light-dependent spin trapping of hydroxyl radical from human erythrocytes.
Biochemical and biophysical research communications 1991;179(3):1305-10.
1991: Myron S Cohen; Bradley E Britigan; Y S Chai; Sovitj Pou; T L Roeder; Gerald M. Rosen
Phagocyte-derived free radicals stimulated by ingestion of iron-rich Staphylococcus aureus: a spin-trapping study.
The Journal of infectious diseases 1991;163(4):819-24.
1991: Sudha Agarwal; Mark A Reynolds; Sovitj Pou; D E Peterson; J A Charon; J B Suzuki
The effect of sanguinarine on human peripheral blood neutrophil viability and functions.
Oral microbiology and immunology 1991;6(1):51-61.
1991: Sovitj Pou; W S Pou; Gerald M. Rosen; Esam E El-Fakahany
N-hydroxylamine is not an intermediate in the conversion of L-arginine to an activator of soluble guanylate cyclase in neuroblastoma N1E-115 cells.
The Biochemical journal 1991;273 ( Pt 3)():547-52.
1991: Sovitj Pou; M Peric; Howard J Halpern; Gerald M. Rosen
Use of a low-frequency ESR spectrometer: implications for spin-trapping free radicals, in situ.
Free radical research communications 1991;12-13 Pt 1():39-46.
1991: Myron S Cohen; Bradley E Britigan; Sovitj Pou; Gerald M. Rosen
Application of spin trapping to human phagocytic cells: insight into conditions for formation and limitation of hydroxyl radical.
Free radical research communications 1991;12-13 Pt 1():17-25.
1990: Sovitj Pou; Gerald M. Rosen
Spin-trapping of superoxide by 5,5-dimethyl-1-pyrroline N-oxide: application to isolated perfused organs.
Analytical biochemistry 1990;190(2):321-5.
1990: Bradley E Britigan; Sovitj Pou; Gerald M. Rosen; D M Lilleg; Garry R Buettner
Hydroxyl radical is not a product of the reaction of xanthine oxidase and xanthine. The confounding problem of adventitious iron bound to xanthine oxidase.
The Journal of biological chemistry 1990;265(29):17533-8.
1990: John D Gottsch; Sovitj Pou; L A Bynoe; Gerald M. Rosen
Hematogenous photosensitization. A mechanism for the development of age-related macular degeneration.
Investigative ophthalmology & visual science 1990;31(9):1674-82.
1990: W S Pou; Sovitj Pou; Gerald M. Rosen; Esam E El-Fakahany
EDRF release is a common pathway in the activation of guanylate cyclase by receptor agonists and calcium ionophores.
European journal of pharmacology 1990;182(2):393-4.
1990: Gerald M. Rosen; M S Cohen; Bradley E Britigan; Sovitj Pou
Application of spin traps to biological systems.
Free radical research communications 1990;9(3-6):187-95.
1989: Sovitj Pou; M S Cohen; Bradley E Britigan; Gerald M. Rosen
Spin-trapping and human neutrophils. Limits of detection of hydroxyl radical.
The Journal of biological chemistry 1989;264(21):12299-302.
1989: Sovitj Pou; Gerald M. Rosen; Bradley E Britigan; Myron S Cohen
Intracellular spin-trapping of oxygen-centered radicals generated by human neutrophils.
Biochimica et biophysica acta 1989;991(3):459-64.
1989: Orazio Cantoni; Piero Sestili; Flaminio Nicola Cattabeni; G Bellomo; Sovitj Pou; M Cohen; P Cerutti
Calcium chelator Quin 2 prevents hydrogen-peroxide-induced DNA breakage and cytotoxicity.
European journal of biochemistry / FEBS 1989;182(2):209-12.
1989: H E Schellhorn; Sovitj Pou; C Moody; H M Hassan
An electron spin resonance study of oxyradical generation in superoxide dismutase- and catalase-deficient mutants of Escherichia coli K-12.
Archives of biochemistry and biophysics 1989;271(2):323-31.
1989: Sovitj Pou; Daniel J Hassett; Bradley E Britigan; M S Cohen; Gerald M. Rosen
Problems associated with spin trapping oxygen-centered free radicals in biological systems.
Analytical biochemistry 1989;177(1):1-6.
1987: John F W Keana; Sovitj Pou; Gerald M. Rosen
Nitroxides as potential contrast enhancing agents for MRI application: influence of structure on the rate of reduction by rat hepatocytes, whole liver homogenate, subcellular fractions, and ascorbate.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1987;5(6):525-36.
1986: E Weber; MS Sonders; M Quarum; S McLean; Sovitj Pou; John F W Keana
1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(22):8784-8.
1985: John F W Keana; Sovitj Pou
Nitroxide-doped liposomes containing entrapped oxidant: an approach to the "reduction problem" of nitroxides as MRI contrast agents.
Physiological chemistry and physics and medical NMR 1985;17(2):235-40.