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Mohammad Pourgholami

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Richard E Kast; Daniel Keizman; Kirsi Ketola; Alireza Khoshnevisan; Nicolas Magné; Christine Marosi; Kerrie McDonald; Miguel Muñoz; Ameya Paranjpe; Mohammad H Pourgholami; Iacopo Sardi; Avishay Sella; Kalkunte S Srivenugopal; Marco Tuccori; Weiguang Wang; Christian R Wirtz; John A Boockvar; Ansgar Brüning; Francesco Cappello; Wen-Wei Chang; Boris Cvek; Q Ping Dou; Alfonso Duenas-Gonzalez; Thomas Efferth; Daniele Focosi; Seyed H Ghaffari; Georg Karpel-Massler; Marc-Eric Halatsch
A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
Mohammad H Pourgholami; Parvin Ataie-Kachoie; Samina Badar; David Lawson Morris
Minocycline inhibits malignant ascites of ovarian cancer through targeting multiple signaling pathways.
Parvin Ataie-Kachoie; Mohammad H Pourgholami; David L Morris
Inhibition of the IL-6 signaling pathway: a strategy to combat chronic inflammatory diseases and cancer.

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All Publications

2013: Richard E Kast; Daniel Keizman; Kirsi Ketola; Alireza Khoshnevisan; Nicolas Magné; Christine Marosi; Kerrie McDonald; Miguel Muñoz; Ameya Paranjpe; Mohammad H Pourgholami; Iacopo Sardi; Avishay Sella; Kalkunte S Srivenugopal; Marco Tuccori; Weiguang Wang; Christian R Wirtz; John A Boockvar; Ansgar Brüning; Francesco Cappello; Wen-Wei Chang; Boris Cvek; Q Ping Dou; Alfonso Duenas-Gonzalez; Thomas Efferth; Daniele Focosi; Seyed H Ghaffari; Georg Karpel-Massler; Marc-Eric Halatsch
A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
Oncotarget 2013;4(4):502-30.
2013: Mohammad H Pourgholami; Parvin Ataie-Kachoie; Samina Badar; David Lawson Morris
Minocycline inhibits malignant ascites of ovarian cancer through targeting multiple signaling pathways.
Gynecologic oncology 2013;129(1):113-9.
2013: Parvin Ataie-Kachoie; Mohammad H Pourgholami; David L Morris
Inhibition of the IL-6 signaling pathway: a strategy to combat chronic inflammatory diseases and cancer.
Cytokine & growth factor reviews 2013;24(2):163-73.
2013: Parvin Ataie-Kachoie; David L Morris; Mohammad H Pourgholami
Minocycline suppresses interleukine-6, its receptor system and signaling pathways and impairs migration, invasion and adhesion capacity of ovarian cancer cells: in vitro and in vivo studies.
PloS one 2013;8(4):e60817.
2012: Chen-Yu Huang; Mohammad H Pourgholami; Barry J Allen
Optimizing radioimmunoconjugate delivery in the treatment of solid tumor.
Cancer treatment reviews 2012;38(7):854-60.
2012: Peyman Mirarabshahii; Krishna Pillai; Mohammad H Pourgholami; Terence C Chua; David L Morris
Diffuse malignant peritoneal mesothelioma--an update on treatment.
Cancer treatment reviews 2012;38(6):605-12.
2012: Samar Masoumi Moghaddam; David L Morris; Afshin Amini; Mohammad H Pourgholami
Significance of vascular endothelial growth factor in growth and peritoneal dissemination of ovarian cancer.
Cancer metastasis reviews 2012;31(1-2):143-62.
2012: Mohammad H Pourgholami; Samina Badar; Ahmed H Mekkawy; David L Morris
Minocycline inhibits growth of epithelial ovarian cancer.
Gynecologic oncology 2012;125(2):433-40.
2012: Yoseop Kim; David L Morris; Mohammad H Pourgholami; Martina H Stenzel
Effect of cross-linking on the performance of micelles as drug delivery carriers: a cell uptake study.
Biomacromolecules 2012;13(3):814-25.
2012: Samar Masoumi Moghaddam; Mohammad H Pourgholami; Ai-Qun Wei; Afshin Amini; David Lawson Morris
Initial report on differential expression of sprouty proteins 1 and 2 in human epithelial ovarian cancer cell lines.
Journal of oncology 2012;2012():373826.
2012: Ahmed H Mekkawy; David L Morris; Mohammad H Pourgholami
HAX1 Augments Cell Proliferation, Migration, Adhesion, and Invasion Induced by Urokinase-Type Plasminogen Activator Receptor.
Journal of oncology 2012;2012():950749.
2012: A Amini; S Masoumi Moghaddam; D L Morris; Mohammad H Pourgholami
The critical role of vascular endothelial growth factor in tumor angiogenesis.
Current cancer drug targets 2012;12(1):23-43.
2012: Afshin Amini; Samar Masoumi Moghaddam; David L Morris; Mohammad H Pourgholami
Utility of vascular endothelial growth factor inhibitors in the treatment of ovarian cancer: from concept to application.
Journal of oncology 2012;2012():540791.
2011: Yoseop Kim; Mohammad H Pourgholami; David L Morris; Martina H Stenzel
An optimized RGD-decorated micellar drug delivery system for albendazole for the treatment of ovarian cancer: from RAFT polymer synthesis to cellular uptake.
Macromolecular bioscience 2011;11(2):219-33.
2011: Li Wang; Hongmin Chen; FengHua Liu; Michele C Madigan; Carl A Power; Jingli Hao; Kate Patterson; Mohammad H Pourgholami; Philippa M O'Brien; Alan C Perkins; Yong Li
Monoclonal antibody targeting MUC1 and increasing sensitivity to docetaxel as a novel strategy in treating human epithelial ovarian cancer.
Cancer letters 2011;300(2):122-33.
2011: Li Wang; Alan C Perkins; Mohammad H Pourgholami; Julia Beretov; Hongtu Chao; Hongmin Chen; Jingli Hao; John H Kearsley; Yong Li
Anti-MUC1 monoclonal antibody (C595) and docetaxel markedly reduce tumor burden and ascites, and prolong survival in an in vivo ovarian cancer model.
PloS one 2011;6(9):e24405.
2011: Krishna Pillai; Javed Akhter; Mohammad H Pourgholami; David L Morris
Peritoneal mesothelioma in a woman who has survived for seven years: a case report.
Journal of medical case reports 2011;5():36.
2010: Ahmed H Mekkawy; Charles E de Bock; Zhen Lin; David L Morris; Yao Wang; Mohammad H Pourgholami
Novel protein interactors of urokinase-type plasminogen activator receptor.
Biochemical and biophysical research communications 2010;399(4):738-43.
2010: Yunjie Zhao; Mohammad H Pourgholami; David L Morris; J Grant Collins; Anthony I Day
Enhanced cytotoxicity of benzimidazole carbamate derivatives and solubilisation by encapsulation in cucurbit[n]uril.
Organic & biomolecular chemistry 2010;8(14):3328-37.
2010: Mohammad H Pourgholami; Levon M Khachigian; Roger G Fahmy; Samina Badar; Lisa Wang; Stephanie Wai Ling Chu; David Lawson Morris
Albendazole inhibits endothelial cell migration, tube formation, vasopermeability, VEGF receptor-2 expression and suppresses retinal neovascularization in ROP model of angiogenesis.
Biochemical and biophysical research communications 2010;397(4):729-34.
2010: Mohammad H Pourgholami; Zhao Y Cai; Stephanie W L Chu; Peter Galettis; David L Morris
The influence of ovarian cancer induced peritoneal carcinomatosis on the pharmacokinetics of albendazole in nude mice.
Anticancer research 2010;30(2):423-8.
2010: Mohammad H Pourgholami; Michael Szwajcer; Melvin Chin; Winston Liauw; Jonathan Seef; Peter Galettis; David L Morris; Matthew Links
Phase I clinical trial to determine maximum tolerated dose of oral albendazole in patients with advanced cancer.
Cancer chemotherapy and pharmacology 2010;65(3):597-605.
2010: Mohammad H Pourgholami; Zhao Y Cai; Samina Badar; Kiran Wangoo; Marianne S Poruchynsky; David L Morris
Potent inhibition of tumoral hypoxia-inducible factor 1alpha by albendazole.
BMC cancer 2010;10():143.
2009: Ahmed H Mekkawy; David L Morris; Mohammad H Pourgholami
Urokinase plasminogen activator system as a potential target for cancer therapy.
Future oncology (London, England) 2009;5(9):1487-99.
2009: Stephanie W L Chu; Samina Badar; David L Morris; Mohammad H Pourgholami
Potent inhibition of tubulin polymerisation and proliferation of paclitaxel-resistant 1A9PTX22 human ovarian cancer cells by albendazole.
Anticancer research 2009;29(10):3791-6.
2009: Mohammad H Pourgholami; Zhao Yan Cai; Lisa Wang; Samina Badar; Matthew Links; David Lawson Morris
Inhibition of cell proliferation, vascular endothelial growth factor and tumor growth by albendazole.
Cancer investigation 2009;27(2):171-7.
2008: Yunjie Zhao; Damian P Buck; David L Morris; Mohammad H Pourgholami; Anthony I Day; J Grant Collins
Solubilisation and cytotoxicity of albendazole encapsulated in cucurbit[n]uril.
Organic & biomolecular chemistry 2008;6(24):4509-15.
2008: Zahid Ghous; Javed Akhter; Mohammad H Pourgholami; David L Morris
Inhibition of hepatocellular cancer by EB1089: in vitro and in vive study.
Anticancer research 2008;28(6A):3757-61.
2008: Mohammad H Pourgholami; David L Morris
Inhibitors of vascular endothelial growth factor in cancer.
Cardiovascular & hematological agents in medicinal chemistry 2008;6(4):343-7.
2008: Mohammad H Pourgholami; Kiran T Wangoo; David L Morris
Albendazole-cyclodextrin complex: enhanced cytotoxicity in ovarian cancer cells.
Anticancer research 2008;28(5A):2775-9.
2007: Azita Khalilzadeh; Kiran T Wangoo; David L Morris; Mohammad H Pourgholami
Epothilone-paclitaxel resistant leukemic cells CEM/dEpoB300 are sensitive to albendazole: Involvement of apoptotic pathways.
Biochemical pharmacology 2007;74(3):407-14.
2007: Zhao-Yan Cai; Peter Galettis; Ying Lu; David L Morris; Mohammad H Pourgholami
Pharmacokinetics of albendazole in New Zealand white rabbits: oral versus intraperitoneal administration.
Anticancer research 2007;27(1A):417-22.
2006: Mohammad H Pourgholami; Zhao Yan Cai; Ying Lu; Lisa Wang; David L Morris
Albendazole: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation in OVCAR-3 tumor-bearing nude mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1928-35.
2005: Mohammad H Pourgholami; Javed Akhter; Lisa Wang; Ying Lu; David L Morris
Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis.
Cancer chemotherapy and pharmacology 2005;55(5):425-32.
2004: Mohammad H Pourgholami; David L Morris
1,25-Dihydroxyvitamin D3 in lipiodol for the treatment of hepatocellular carcinoma: cellular, animal and clinical studies.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):513-8.
2004: Mohammad H Pourgholami; Ying Lu; Lisa Wang; Ross W Stephens; David L Morris
Regression of Novikoff rat hepatocellular carcinoma following locoregional administration of a novel formulation of clofazimine in lipiodol.
Cancer letters 2004;207(1):37-47.
2003: Mehdi Saberi; Mohammad H Pourgholami
Estradiol alters afterdischarge threshold and acquisition of amygdala kindled seizures in male rats.
Neuroscience letters 2003;340(1):41-4.
2002: David L Morris; JL Jourdan; Ian Finlay; Thomas Gruenberger; M P The; Mohammad H Pourgholami
Hepatic intra-arterial injection of 1,25-dihydroxyvitamin D3 in lipiodol: Pilot study in patients with hepatocellular carcinoma.
International journal of oncology 2002;21(4):901-6.
2002: Javad Mirnajafi-Zadeh; Mohammad H Pourgholami
Hippocampal hyperexcitability facilitates amygdala kindling in rats.
The Indian journal of medical research 2002;116():35-40.
2001: IG Finlay; GJ Stewart; P Shirley; S Woolfe; Mohammad H Pourgholami; David L Morris
Hepatic arterial and intravenous administration of 1,25-dihydroxyvitamin D3--evidence of a clinically significant hepatic first-pass effect.
Cancer chemotherapy and pharmacology 2001;48(3):209-14.
2001: Javed Akhter; Ying Lu; Ian Finlay; Mohammad H Pourgholami; David L Morris
1alpha,25-Dihydroxyvitamin D3 and its analogues, EB1089 and CB1093, profoundly inhibit the in vitro proliferation of the human hepatoblastoma cell line HepG2.
ANZ journal of surgery 2001;71(7):414-7.
2001: Mehdi Saberi; M Jorjani; Mohammad H Pourgholami
Effects of chronic estradiol benzoate treatment on amygdala kindled seizures in male rats.
Epilepsy research 2001;46(1):45-51.
2001: Mohammad H Pourgholami; L Woon; R Almajd; Javed Akhter; P Bowery; David L Morris
In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole.
Cancer letters 2001;165(1):43-9.
2001: Mehdi Saberi; Mohammad H Pourgholami; M Jorjani
The acute effects of estradiol benzoate on amygdala-kindled seizures in male rats.
Brain research 2001;891(1-2):1-6.
2001: David L Morris; JL Jourdan; Mohammad H Pourgholami
Pilot study of albendazole in patients with advanced malignancy. Effect on serum tumor markers/high incidence of neutropenia.
Oncology 2001;61(1):42-6.
2000: Mohammad H Pourgholami; Javed Akhter; David L Morris
In vitro antiproliferative activity of a medium-chain triglyceride solution of 1,25-dihydroxyvitamin D3 in HepG2 cells.
Anticancer research 2000;20(6B):4257-60.
2000: JL Jourdan; Javed Akhter; Patricia Bowrey; Mohammad H Pourgholami; David L Morris
Hepatic intra-arterial injection of lipiodol-1,25-dihydroxyvitamin D3 for hepatocellular carcinoma in rats.
Anticancer research 2000;20(4):2739-44.
2000: IG Finlay; GJ Stewart; Mohammad H Pourgholami; Javed Akhter; David L Morris
The use of lipiodol and medium chain triglyceride as delivery agents for hepatic arterial administration of 1, 25-dihydroxyvitamin D3--a potential new treatment for hepatocellular carcinoma.
Anticancer research 2000;20(4):2705-9.
2000: Mohammad H Pourgholami; Javed Akhter; Ying Lu; David L Morris
In vitro and in vivo inhibition of liver cancer cells by 1,25-dihydroxyvitamin D3.
Cancer letters 2000;151(1):97-102.
2000: Javad Mirnajafi-Zadeh; Yaghoub Fathollahi; Mohammad H Pourgholami
Intraperitoneal and intraamygdala N(6)-cyclohexyladenosine suppress hippocampal kindled seizures in rats.
Brain research 2000;858(1):48-54.
2000: Mohammad H Pourgholami; Javed Akhter; IG Finlay; David L Morris
1,25-dihydroxyvitamin D3 dissolved in lipiodol produces a sustained antiproliferative effect in the human hepatoblastoma cell line HepG2.
Anticancer research 2000;20(2A):723-7.
1999: Javad Mirnajafi-Zadeh; Mohammad H Pourgholami; Mohammad Reza Palizvan; Mohammad Rostampour; M Fallahi
Anticonvulsant action of 2-chloroadenosine injected focally into the perirhinal cortex in amygdaloid kindled rats.
Epilepsy research 1999;37(1):37-43.
1999: Mohammad H Pourgholami; Sayeh Majzoob; Mohammad Ali Javadi; Mohammad Kamalinejad; G H Fanaee; Mohammad Sayyah
The fruit essential oil of Pimpinella anisum exerts anticonvulsant effects in mice.
Journal of ethnopharmacology 1999;66(2):211-5.
1999: Mohammad H Pourgholami; Mohammad Kamalinejad; Mohammad Ali Javadi; Sayeh Majzoob; Mohammad Sayyah
Evaluation of the anticonvulsant activity of the essential oil of Eugenia caryophyllata in male mice.
Journal of ethnopharmacology 1999;64(2):167-71.
1998: S Mohammad; A Abolhassan; Mohammad H Pourgholami
Evaluation of the anticonvulsant profile of progesterone in male amygdala-kindled rats.
Epilepsy research 1998;30(3):195-202.
1997: Mohammad H Pourgholami; Mohammad Rostampour; Javad Mirnajafi-Zadeh; Mohammad Reza Palizvan
Intra-amygdala infusion of 2-chloroadenosine suppresses amygdala-kindled seizures.
Brain research 1997;775(1-2):37-42.
1997: Mohammad H Pourgholami; Javad Mirnajafi-Zadeh; J Behzadi
Effect of intraperitoneal and intrahippocampal (CA1) 2-chloroadenosine in amygdaloid kindled rats.
Brain research 1997;751(2):259-64.
1995: Mohammad H Pourgholami; F Goshadrou
Evidence for serotonergic system involvement in the effect of morphine on gastrointestinal motility in the rat.
General pharmacology 1995;26(4):779-83.