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Alan Pourpak

Research Profile

Chemicals & Drugs

Anatomy

Tumor Cell Line

Procedures

Xenograft Model Antitumor Assays

Physiology

Cell Survival

Living Beings

Disorders

Melanoma

Concepts & Ideas

Drug Dose Response Relationship

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Publications

TOP 3
Ross O Meyers; Joshua D Lambert; Nicole Hajicek; Alan Pourpak; John A Kalaitzis; Robert T Dorr
Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid.
Lauren M Congdon; Alan Pourpak; Aluvia M Escalante; Robert T Dorr; Terry Landowski
Proteasomal inhibition stabilizes topoisomerase IIalpha protein and reverses resistance to the topoisomerase II poison ethonafide (AMP-53, 6-ethoxyazonafide).
Kexiao Guo; Alan Pourpak; Kara Beetz-Rogers; Vijay Gokhale; Daekyu Sun; Laurence H Hurley
Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene.

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All Publications

2009: Ross O Meyers; Joshua D Lambert; Nicole Hajicek; Alan Pourpak; John A Kalaitzis; Robert T Dorr
Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid.
Bioorganic & medicinal chemistry letters 2009;19(16):4752-5.
2008: Lauren M Congdon; Alan Pourpak; Aluvia M Escalante; Robert T Dorr; Terry Landowski
Proteasomal inhibition stabilizes topoisomerase IIalpha protein and reverses resistance to the topoisomerase II poison ethonafide (AMP-53, 6-ethoxyazonafide).
Biochemical pharmacology 2008;75(4):883-90.
2007: Kexiao Guo; Alan Pourpak; Kara Beetz-Rogers; Vijay Gokhale; Daekyu Sun; Laurence H Hurley
Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene.
Journal of the American Chemical Society 2007;129(33):10220-8.
2007: Alan Pourpak; Terry Landowski; Robert T Dorr
Ethonafide-induced cytotoxicity is mediated by topoisomerase II inhibition in prostate cancer cells.
The Journal of pharmacology and experimental therapeutics 2007;321(3):1109-17.
2007: Alan Pourpak; Robert T Dorr; Ross O Meyers; Marianne Powell; Steven P Stratton
Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line.
Investigational new drugs 2007;25(2):107-14.
2006: Alan Pourpak; Ross O Meyers; Betty K Samulitis; H-H Sherry Chow; Carole Y Kepler; Mary Ann Raymond; Evan M Hersh; Robert T Dorr
Preclinical antitumor activity, pharmacokinetics and pharmacodynamics of imexon in mice.
Anti-cancer drugs 2006;17(10):1179-84.

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